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Bekes F, Hidvegi M, Zsigmond A, Lasztity R: A novel mathematical model for determining in vitro biological value of proteins and its application for non-linear optimization of the nutritional quality of feed and food formulas. In: Progress in Cereal
Science and Technology Vol. 5B, J. Holas and J.
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Fajka-Boja R, Hidvegi M, Shoenfeld Y, Ion G, Demydenko D, Tomoskozi-Farkas R, Vizler Cs, Telekes A, Resetar A, Monostori E: Fermented wheat germ extract induces apoptosis and downregulation of major histocompatibility complex class I proteins in tumor T and B cell lines. Int J Oncol 20: 563-570,
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Saiko P, Ozsvar-Kozma M, Graser G, Lackner A, Grusch M, Madlener S, Krupitza G, Jaeger W, Hidvegi M, Agarwal RP, Fritzer-Szekeres M, Szekeres T: Avemar, a nontoxic fermented wheat germ extract, attenuates the growth of sensitive and 5-FdUrd/Ara-C cross-resistant H9 human lymphoma cells through
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from 1984-1987 as assistant professor and since 1992 as professor. After finishing university, he worked in the cereal industry and was co-developer of a patented feed advisory system based on near infrared ingredient data. Hidvegi was the pioneer in the development of technologies of
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Hidvegi's first publications were about the theories of the origins of life, and the elaboration of a plausible mechanism for the biogenesis and evolution of biomembranes. He worked out the metabolic map as well as the reaction kinetics of a theoretical first living cell.
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Boros L. G, Lapis K, Szende B, Tomoskozi-Farkas R, Balogh A, Boren J, Marin S, Cascante M, Hidvegi M: Wheat germ extract decreases glucose uptake and RNA ribose formation but increases fatty acid synthesis in MIA pancreatic adenocarcinoma cells. Pancreas 23: 141-147,
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Jakab F, Shoenfeld Y, Balogh A, Nichelatti M, Hoffmann A, Kahan Zs, Lapis K, Mayer A, Sapy P, Szentpetery F, Telekes A, Thurzo L, Vagvolgyi A, Hidvegi M: A medical nutriment has supportive value in the treatment of colorectal cancer. Br J Cancer 89: 465-469,
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Balint G, Apathy A, Gaal M, Telekes A, Resetar A, Blazso G, Falkay G, Szende B, Paksy A, Ehrenfeld M, Shoenfeld Y, Hidvegi M: Effect of Avemar - a fermented wheat germ extract - on rheumatoid arthritis. Preliminary data. Clin Exp
Rheumatol 24: 325-328,
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Garami M, Schuler D, Babosa M, Borgulya G, Hauser P, Müller J, Paksy A, Szabó E, Hidvegi M, Fekete Gy: Fermented wheat germ extract reduces chemotherapy-induced febrile neutropenia in pediatric cancer patients. J Pediatric
Hematol Oncol 10: 631-635,
303:-based nutraceutical known as Avemar. In the U.S., Avemar is classified as a dietary supplement and marketed under the trade name Ave (American BioSciences, Inc.; Blauvelt, NY). In Hungary Avemar as a dietary food for cancer patients.
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Ehrenfeld M, Blank M, Shoenfeld Y, Hidvegi M: Avemar (a new benzoquinone-containing natural product) administration interferes with the Th2 response in experimental SLE and promotes amelioration of the disease. Lupus 10: 622-627,
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He received his
Bachelor of Science in 1978 and Master of Science in 1980 from Technology University Budapest. He also received his Doctor of Philosophy from Technology University Budapest in 1983.Then he taught at what is now
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In 1996 Hidvegi was co-founder of
Biromedicina (joint stock company), what is now called The First Hungarian Corporation for Cancer Research and Oncology. The company’s mission was to market Hidvegi's product Avemar, a
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Telekes A, Resetar A, Balint G, Blazso G, Falkay G, Lapis K, Raso E, Szende B, Ehrenfeld M, Shoenfeld Y, Hidvegi M. Fermented wheat germ extract (Avemar) inhibits adjuvant arthritis. Ann N Y Acad Sci 1110: 348-361,
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Stipkovits L, Lapis K, Hidvegi M, Kosa E, Glavits R, Resetar A: Testing the efficacy of fermented wheat germ extract against
Mycoplasma gallisepticum infection of chicken. Poultry Sci 11: 1844-1848, 2004.
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Hidvegi invented and hold the patent for the manufacturing process of an alfalfa-based extract (Esterin), which has been claimed to lower serum cholesterol levels (U.S patent 5,277,910 January 11, 1994).
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Hidvegi M, Raso E, Tomoskozi-Farkas R, Szende B, Paku S, Prónai L, Bocsi J, Lapis K: MSC, a new benzoquinone-containing natural product with antimetastatic effect. Cancer
Biother Radiopharm 14: 277-289,
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Hidvegi M, Raso E, Tomoskozi-Farkas R, Paku S, Lapis K, Szende B: The effect of Avemar and Avemar + vitamin C on tumor growth and metastasis in experimental animals. Anticancer Res 18: 2353-2358, 1998.
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Boros LG, Lee W-NP, Hidvegi M, Go VLW: Metabolic effects of fermented wheat germ extract with anti-tumor properties in cultured MIA pancreatic adenocarcinoma cells. Pancreas 21: 434, 2000.
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Zalatnai A, Lapis K, Szende B, Raso E, Telekes A, Resetar A, Hidvegi M: Wheat germ extract inhibits experimental colon carcinogenesis in F-344 rats. Carcinogenesis 22: 1649-1652, 2001.
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Tomoskozi-Farkas R, Hidvegi M, Lasztity R: Investigation of methoxy-substituted benzoquinone derivatives in tree samples grown in
Hungary. Acta Biol Hung 49: 79-87, 1998.
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mass-production and therapeutic use of instantized herbal extracts in
Hungary. Between 1988-1990 Hidvegi was Post-Doctoral Fellow at the Grain Research Laboratory of the
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In 2009 Hidvegi marketed a new dietary food for special medical purposes for cancer patients based on the Avemar, which was sold as
Oncomar and (in the U.S.) AvéUltra.
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Jakab F, Mayer A, Hoffmann A, Hidvegi M: First clinical data of a natural immunomodulator in colorectal cancer. Hepatogastroenterology 47: 393-395, 2000.
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Hidvegi M, Raso E, Tomoskozi-Farkas R, Lapis K, Szende B: Effect of MSC on the immune response of mice. Immunopharmacology 41: 183-186, 1999.
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Mercer LP, Haijazi H, Hidvegi M: Weanling rats display bioperiodicity of growth and food intake rates. J Nutrition 123: 1356-1362, 1993.
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You can help by adding reliable sources to this article. Contentious material about living people that is unsourced or poorly sourced
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Lasztity R, Hidvegi M (eds): Amino acid composition and biological value of cereal proteins. D. Reidel Publ Co., Boston, 1985.
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Hidvegi was born in Budapest, Hungary, on 9 November 1955. He is the son of György Hidvégi-Hoffmann and Katalin Dávid.
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Hidvegi holds a PhD and a Dr. Habil in chemistry, and an honorary professorship at the
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Lasztity R, Hidvegi M, Bata A: Saponins in food. Food Rev Int 14: 371-390, 1998.
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Kratochvil, Eds., Elsevier Publ., Amsterdam, 1983. pp. 1213–1218.
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Development of fermented wheat germ extract (Avemar/Ave)
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induction of apoptosis. Oncol Rep 21: 787-791, 2009.
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