2034:
558:
146:(CSIs) present in diverse proteins that are exclusively shared by these pathogens. Due to their exclusivity for the MTC complex and presence in highly conserved regions of proteins, these CSIs provide novel means for functional and diagnostic studies (including potential targets for development of novel therapeutics).
202:
As MTBC diverged into different lineages, so did the expression of key and metabolic pathogenic genes, as a result of mutations introducing new TANNNT Pribnow boxes and mutations that impair the function of transcriptional repressors. This provides clear evidence that MTBC lineages probably reflect
181:
on the whole-genome level, failing the criteria to be considered independent species. The same applies to "M. canetti", "M. mungi", and "M. orygis", species not validly published. The variation is even below the accepted level for subspecies. Authors of the article note that these names do refer to
210:
The role of methylation is more elusive, the mutation inactivation pattern seems to confirm that methylases are not preserved throughout mtBC. Transcriptional adaptation can allow M. tuberculosis isolates to optimize their infectivity and transmission in subtly different environments provided by
206:
This can be seen reflected in the way that the different MTBC clades have their own transcriptomic signature. Even single-point mutations can completely change the transcriptional profile of a strain. An example is the N1177 strain, which carries a single mutation in the rpoB gene that confers
464:"Phylogenomic analysis of the species of the Mycobacterium tuberculosis complex demonstrates that Mycobacterium africanum, Mycobacterium bovis, Mycobacterium caprae, Mycobacterium microti and Mycobacterium pinnipedii are later heterotypic synonyms of Mycobacterium tuberculosis"
405:"Impact of Genomics on Clarifying the Evolutionary Relationships amongst Mycobacteria: Identification of Molecular Signatures Specific for the Tuberculosis-Complex of Bacteria with Potential Applications for Novel Diagnostics and Therapeutics"
138:
In addition, two branches exist which have phylogenetic similarities but are not completely described: the dassie and oryx bacilli. Oryx bacilli has been recently reclassified into a separate subspecies, orygis.
203:
adaptation to different human populations. In fact, modifying gene expression could be a rapid mechanism for physiological adaptation to a new environment without the need to substantially change the genome.
158:
2075:
877:
593:
720:
2068:
1537:
1819:
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1371:
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1775:
1711:
462:
Riojas, Marco A.; McGough, Katya J.; Rider-Riojas, Cristin J.; Rastogi, Nalin; HazbĂłn, Manzour
Hernando (1 January 2018).
1853:
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220:
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987:
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2011:
2004:
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Chiner-Oms Ă, Berney M, Boinett C, GonzĂĄlez-Candelas F, Young DB, Gagneux S, et al. (September 2019).
1986:
1958:
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1168:
1154:
1048:
1034:
997:
752:
732:
726:
690:
620:
579:
510:"Genome-wide mutational biases fuel transcriptional diversity in the Mycobacterium tuberculosis complex"
96:
1938:
1913:
1876:
1766:
1682:
1574:
1568:
1562:
1299:
1201:
1160:
1123:
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521:
305:
110:
77:
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1752:
1647:
871:
821:
676:
84:
1813:
182:
stable lineages with meaningful clinical distinctions, recommending that them become variants:
547:
485:
444:
426:
382:
331:
274:
243:
van Ingen J, Rahim Z, Mulder A, Boeree MJ, Simeone R, Brosch R, van
Soolingen D (April 2012).
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624:
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264:
256:
571:
349:
Vasconcellos SE, Huard RC, Niemann S, Kremer K, Santos AR, Suffys PN, Ho JL (March 2010).
150:
294:"Social and environmental factors affect tuberculosis related mortality in wild meerkats"
525:
309:
2045:
636:
542:
509:
439:
404:
377:
350:
326:
293:
269:
244:
17:
142:
Members of the MTC can be distinguished from all other bacteria by the presence of 63
2088:
2041:
1746:
1243:
1026:
912:
602:
47:
2033:
52:
351:"Distinct genotypic profiles of the two major clades of Mycobacterium africanum"
245:"Characterization of Mycobacterium orygis as M. tuberculosis complex subspecies"
89:
562:
533:
207:
resistance to rifampicin that modified transcription levels of multiple genes.
430:
367:
317:
551:
489:
480:
463:
448:
386:
335:
278:
260:
783:
557:
421:
561:
Material was copied from this source, which is available under a
468:
International
Journal of Systematic and Evolutionary Microbiology
292:
Patterson, S, Drewe, JA, Pfeiffer, DU, Clutton-Brock, TH (2017).
575:
27:
Closely related bacterium species that cause tuberculosis
2049:
503:
501:
499:
563:
Creative
Commons Attribution 4.0 International License
1996:
1923:
1805:
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1554:
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1235:
1193:
1147:
1102:
1093:
1066:
1025:
979:
847:
840:
654:
645:
614:
157:as far as bacterial nomenclature is concerned. The
2069:
587:
8:
2076:
2062:
1551:
1457:
1239:
1099:
844:
651:
642:
594:
580:
572:
541:
479:
438:
420:
376:
366:
325:
268:
232:
45:) is a genetically related group of
7:
2030:
2028:
398:
396:
238:
236:
211:different human host populations.
25:
2032:
556:
149:Since 2018, all members of this
403:Gupta, Radhey S. (2018-10-02).
177:are 99.21â99.92% identical to
1:
2048:. You can help Knowledge by
249:Emerging Infectious Diseases
55:in humans or other animals.
221:Nontuberculous mycobacteria
153:are considered synonyms of
2121:
2027:
534:10.1038/s41467-019-11948-6
144:conserved signature indels
64:Mycobacterium tuberculosis
33:Mycobacterium tuberculosis
298:Journal of Animal Ecology
125:Mycobacterium suricattae
118:Mycobacterium pinnipedii
90:Bacillus CalmetteâGuĂ©rin
368:10.1186/1471-2334-10-80
355:BMC Infectious Diseases
318:10.1111/1365-2656.12649
71:Mycobacterium africanum
51:species that can cause
18:M. tuberculosis complex
1538:M. fluoroanthenivorans
481:10.1099/ijsem.0.002507
261:10.3201/eid1804.110888
104:Mycobacterium canettii
773:M. ulcerans liflandii
655:M. tuberculosis group
514:Nature Communications
161:article reports that
97:Mycobacterium microti
1820:M. thermoresistibile
1513:M. frederiksbergense
1382:M. intermedium group
1359:M. interjectum group
980:M. haemophilum group
111:Mycobacterium caprae
78:Mycobacterium orygis
1997:M. elephantis group
1699:M. chlorophenolicum
1372:M. saskatchewanense
1331:M. parascrofulaceum
1216:M. nonchromogenicum
1067:M. conspicuum group
526:2019NatCo..10.3994C
310:2017JAnEc..86..442P
132:Mycobacterium mungi
85:Mycobacterium bovis
2105:Mycobacteria stubs
1899:M. madagascariense
1806:M. smegmatis group
1776:M. austroafricanum
1712:M. psychrotolerans
1555:M. fortuitum group
1194:M. hiberniae group
2057:
2056:
2025:
2024:
2021:
2020:
1924:M. chelonae group
1854:M. conceptionense
1801:
1800:
1601:M. neworleansense
1461:M. neoaurum group
1442:
1441:
1399:
1398:
1287:M. heidelbergense
1231:
1230:
1131:M. heckeshornense
1089:
1088:
1027:M. gordonae group
1021:
1020:
866:M. intracellulare
848:M. kansasii group
745:M. pseudoshottsii
422:10.3390/ht7040031
16:(Redirected from
2112:
2078:
2071:
2064:
2036:
2029:
1886:
1871:M. novocastrense
1863:
1741:
1692:
1689:M. parafortuitum
1651:
1628:
1552:
1458:
1360:
1323:
1322:M. kubicae group
1280:M. montefiorense
1253:
1240:
1148:M. celatum group
1100:
915:
883:paratuberculosis
858:
845:
829:M. kumamotonense
814:
786:
723:
665:
652:
643:
631:scotochromogenic
625:photochromogenic
596:
589:
582:
573:
566:
560:
555:
545:
505:
494:
493:
483:
459:
453:
452:
442:
424:
400:
391:
390:
380:
370:
346:
340:
339:
329:
289:
283:
282:
272:
240:
21:
2120:
2119:
2115:
2114:
2113:
2111:
2110:
2109:
2085:
2084:
2083:
2082:
2026:
2017:
1992:
1919:
1868:
1845:
1797:
1783:M. pyrenivorans
1723:
1674:
1668:M. vaccae group
1663:
1658:M. farcinogenes
1633:
1598:
1543:
1485:M. canariasense
1451:
1448:Rapidly growing
1438:
1395:
1377:
1358:
1321:
1252:M. simiae group
1251:
1244:M. simiae clade
1227:
1189:
1143:
1103:M. xenopi group
1095:
1085:
1062:
1017:
975:
968:M. scrofulaceum
911:
854:
836:
812:
805:M. lepromatosis
798:M. lepraemurium
782:
719:
670:M. tuberculosis
661:
647:
634:
628:
618:
610:
600:
570:
569:
507:
506:
497:
461:
460:
456:
409:High-Throughput
402:
401:
394:
348:
347:
343:
291:
290:
286:
242:
241:
234:
229:
217:
200:
194:, for example.
188:M. tuberculosis
179:M. tuberculosis
155:M. tuberculosis
151:species complex
28:
23:
22:
15:
12:
11:
5:
2118:
2116:
2108:
2107:
2102:
2097:
2087:
2086:
2081:
2080:
2073:
2066:
2058:
2055:
2054:
2037:
2023:
2022:
2019:
2018:
2016:
2015:
2008:
2000:
1998:
1994:
1993:
1991:
1990:
1983:
1980:M. massiliense
1976:
1973:M. immunogenum
1969:
1962:
1955:
1948:
1935:
1927:
1925:
1921:
1920:
1918:
1917:
1903:
1902:
1893:M. confluentis
1888:
1887:
1865:
1864:
1860:M. moriokaense
1843:
1836:
1823:
1809:
1807:
1803:
1802:
1799:
1798:
1796:
1795:
1787:
1786:
1779:
1772:
1771:
1770:
1763:
1760:M. vanbaalenii
1756:
1743:
1742:
1732:M. mucogenicum
1721:
1708:
1694:
1693:
1671:
1669:
1665:
1664:
1662:
1661:
1653:
1652:
1630:
1629:
1625:M. senegalense
1595:
1594:
1591:M. houstonense
1587:
1579:
1578:
1558:
1556:
1549:
1545:
1544:
1542:
1541:
1533:
1532:
1529:M. brisbanense
1524:
1523:
1516:
1509:
1502:
1499:M. diernhoferi
1495:
1488:
1480:
1479:
1472:
1469:M. mageritense
1464:
1462:
1455:
1444:
1443:
1440:
1439:
1437:
1436:
1429:
1422:
1415:
1407:
1405:
1401:
1400:
1397:
1396:
1394:
1393:
1390:M. intermedium
1385:
1383:
1379:
1378:
1376:
1375:
1368:
1365:M. interjectum
1361:
1355:
1354:
1353:
1352:
1336:
1335:
1334:
1324:
1318:
1317:
1316:
1315:
1312:M. lentiflavum
1305:
1304:
1303:
1296:
1283:
1274:M. florentinum
1270:
1254:
1248:
1246:
1237:
1236:Short helix 18
1233:
1232:
1229:
1228:
1226:
1225:
1212:
1205:
1197:
1195:
1191:
1190:
1188:
1187:
1186:
1185:
1178:
1166:
1165:
1164:
1151:
1149:
1145:
1144:
1142:
1141:
1134:
1127:
1114:
1106:
1104:
1097:
1091:
1090:
1087:
1086:
1084:
1083:
1082:
1081:
1070:
1068:
1064:
1063:
1061:
1060:
1059:
1058:
1046:
1045:
1044:
1031:
1029:
1023:
1022:
1019:
1018:
1016:
1015:
1014:
1013:
1003:
1002:
1001:
991:
988:M. haemophilum
983:
981:
977:
976:
974:
973:
972:
971:
961:
960:
959:
952:
949:M. nebraskense
941:
940:
939:
938:
928:
927:
926:
916:
908:
907:
906:
905:
895:
894:
893:
886:
875:
859:
851:
849:
842:
838:
837:
835:
834:
833:
832:
825:
815:
809:
808:
801:
794:
787:
779:
778:
777:
776:
769:
762:
750:
749:
748:
738:
737:
736:
724:
716:
715:
708:
701:
694:
687:
680:
673:
666:
658:
656:
649:
640:
637:nonchromogenic
616:Slowly growing
612:
611:
607:Nontuberculous
601:
599:
598:
591:
584:
576:
568:
567:
495:
474:(1): 324â332.
454:
392:
341:
304:(3): 442â450.
284:
231:
230:
228:
225:
224:
223:
216:
213:
199:
196:
136:
135:
128:
121:
114:
107:
100:
93:
81:
74:
67:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
2117:
2106:
2103:
2101:
2098:
2096:
2093:
2092:
2090:
2079:
2074:
2072:
2067:
2065:
2060:
2059:
2053:
2051:
2047:
2044:article is a
2043:
2042:Mycobacterium
2038:
2035:
2031:
2014:
2013:
2012:M. holsaticum
2009:
2007:
2006:
2005:M. elephantis
2002:
2001:
1999:
1995:
1989:
1988:
1984:
1982:
1981:
1977:
1975:
1974:
1970:
1968:
1967:
1963:
1961:
1960:
1956:
1954:
1953:
1949:
1947:
1946:
1941:
1940:
1936:
1934:
1933:
1932:M. komossense
1929:
1928:
1926:
1922:
1916:
1915:
1910:
1909:
1905:
1904:
1901:
1900:
1895:
1894:
1890:
1889:
1885:
1884:
1879:
1878:
1873:
1872:
1867:
1866:
1862:
1861:
1856:
1855:
1850:
1849:
1844:
1842:
1841:
1837:
1835:
1834:
1833:M. flavescens
1829:
1828:
1824:
1822:
1821:
1816:
1815:
1811:
1810:
1808:
1804:
1794:
1793:
1789:
1788:
1785:
1784:
1780:
1778:
1777:
1773:
1769:
1768:
1764:
1762:
1761:
1757:
1755:
1754:
1750:
1749:
1748:
1745:
1744:
1740:
1739:
1734:
1733:
1728:
1727:
1726:M. aubagnense
1722:
1720:
1719:
1714:
1713:
1709:
1707:
1706:
1701:
1700:
1696:
1695:
1691:
1690:
1685:
1684:
1679:
1678:
1673:
1672:
1670:
1666:
1660:
1659:
1655:
1654:
1650:
1649:
1644:
1643:
1642:M. peregrinum
1638:
1637:
1632:
1631:
1627:
1626:
1621:
1620:
1615:
1614:
1609:
1608:
1603:
1602:
1597:
1596:
1593:
1592:
1588:
1586:
1585:
1581:
1580:
1577:
1576:
1571:
1570:
1565:
1564:
1560:
1559:
1557:
1553:
1550:
1546:
1540:
1539:
1535:
1534:
1531:
1530:
1526:
1525:
1522:
1521:
1517:
1515:
1514:
1510:
1508:
1507:
1503:
1501:
1500:
1496:
1494:
1493:
1492:M. cosmeticum
1489:
1487:
1486:
1482:
1481:
1478:
1477:
1473:
1471:
1470:
1466:
1465:
1463:
1459:
1456:
1454:
1449:
1445:
1435:
1434:
1430:
1428:
1427:
1423:
1421:
1420:
1416:
1414:
1413:
1409:
1408:
1406:
1402:
1392:
1391:
1387:
1386:
1384:
1380:
1374:
1373:
1369:
1367:
1366:
1362:
1357:
1356:
1351:
1350:
1345:
1344:
1340:
1339:
1337:
1333:
1332:
1328:
1327:
1325:
1320:
1319:
1314:
1313:
1309:
1308:
1306:
1302:
1301:
1297:
1295:
1294:
1289:
1288:
1284:
1282:
1281:
1276:
1275:
1271:
1269:
1268:
1263:
1262:
1258:
1257:
1255:
1250:
1249:
1247:
1245:
1241:
1238:
1234:
1224:
1223:
1218:
1217:
1213:
1211:
1210:
1206:
1204:
1203:
1199:
1198:
1196:
1192:
1184:
1183:
1179:
1177:
1176:
1172:
1171:
1170:
1167:
1163:
1162:
1158:
1157:
1156:
1153:
1152:
1150:
1146:
1140:
1139:
1135:
1133:
1132:
1128:
1126:
1125:
1120:
1119:
1115:
1113:
1112:
1108:
1107:
1105:
1101:
1098:
1094:Long helix 18
1092:
1080:
1079:
1078:M. conspicuum
1075:
1074:
1072:
1071:
1069:
1065:
1057:
1056:
1052:
1051:
1050:
1047:
1043:
1042:
1038:
1037:
1036:
1033:
1032:
1030:
1028:
1024:
1012:
1011:
1007:
1006:
1004:
1000:
999:
995:
994:
992:
990:
989:
985:
984:
982:
978:
970:
969:
965:
964:
962:
958:
957:
953:
951:
950:
946:
945:
943:
942:
937:
936:
932:
931:
929:
925:
924:
920:
919:
917:
914:
910:
909:
904:
903:
899:
898:
896:
892:
891:
887:
885:
884:
880:
876:
874:
873:
868:
867:
863:
862:
860:
857:
853:
852:
850:
846:
843:
839:
831:
830:
826:
824:
823:
819:
818:
816:
811:
810:
807:
806:
802:
800:
799:
795:
793:
792:
788:
785:
781:
780:
775:
774:
770:
768:
767:
763:
761:
760:
756:
755:
754:
751:
747:
746:
742:
741:
739:
735:
734:
730:
729:
728:
725:
722:
718:
717:
714:
713:
712:M. pinnipedii
709:
707:
706:
702:
700:
699:
695:
693:
692:
688:
686:
685:
681:
679:
678:
674:
672:
671:
667:
664:
660:
659:
657:
653:
650:
646:Long helix 18
644:
641:
638:
632:
626:
622:
617:
613:
608:
604:
597:
592:
590:
585:
583:
578:
577:
574:
564:
559:
553:
549:
544:
539:
535:
531:
527:
523:
519:
515:
511:
504:
502:
500:
496:
491:
487:
482:
477:
473:
469:
465:
458:
455:
450:
446:
441:
436:
432:
428:
423:
418:
414:
410:
406:
399:
397:
393:
388:
384:
379:
374:
369:
364:
360:
356:
352:
345:
342:
337:
333:
328:
323:
319:
315:
311:
307:
303:
299:
295:
288:
285:
280:
276:
271:
266:
262:
258:
254:
250:
246:
239:
237:
233:
226:
222:
219:
218:
214:
212:
208:
204:
198:Phylogenetics
197:
195:
193:
189:
186:would become
185:
180:
176:
175:M. pinnipedii
172:
168:
164:
160:
156:
152:
147:
145:
140:
134:
133:
129:
127:
126:
122:
120:
119:
115:
113:
112:
108:
106:
105:
101:
99:
98:
94:
91:
87:
86:
82:
80:
79:
75:
73:
72:
68:
66:
65:
61:
60:
59:
58:It includes:
56:
54:
50:
49:
48:Mycobacterium
44:
40:
36:
34:
19:
2100:Tuberculosis
2095:Mycobacteria
2050:expanding it
2039:
2010:
2003:
1985:
1978:
1971:
1966:M. abscessus
1964:
1957:
1952:M. aichiense
1950:
1945:M. tokaiense
1943:
1937:
1930:
1912:
1908:M. smegmatis
1906:
1897:
1891:
1881:
1875:
1869:
1858:
1852:
1846:
1840:M. monacense
1838:
1831:
1825:
1818:
1812:
1792:M. poriferae
1790:
1781:
1774:
1765:
1758:
1751:
1738:M. phocaicum
1736:
1730:
1724:
1716:
1710:
1705:M. chubuense
1703:
1697:
1687:
1681:
1675:
1656:
1646:
1640:
1634:
1623:
1617:
1613:M. fortuitum
1611:
1607:M. boenickei
1605:
1599:
1589:
1584:M. rhodesiae
1582:
1573:
1567:
1561:
1536:
1527:
1518:
1511:
1504:
1497:
1490:
1483:
1476:M. wolinskyi
1474:
1467:
1433:M. arosiense
1431:
1424:
1417:
1410:
1388:
1370:
1363:
1347:
1341:
1329:
1310:
1298:
1291:
1285:
1278:
1272:
1265:
1261:M. genavense
1259:
1220:
1214:
1209:M. hiberniae
1207:
1200:
1180:
1173:
1159:
1138:M. hassiacum
1136:
1129:
1122:
1118:M. shimoidei
1116:
1111:M. botniense
1109:
1076:
1053:
1041:M. asiaticum
1039:
1010:M. malmoense
1008:
996:
986:
966:
956:M. seoulense
954:
947:
933:
921:
902:M. bohemicum
900:
888:
882:
878:
870:
864:
827:
820:
803:
796:
789:
771:
764:
757:
743:
731:
710:
703:
696:
689:
684:M. africanum
682:
675:
668:
662:
603:Mycobacteria
517:
513:
471:
467:
457:
412:
408:
358:
354:
344:
301:
297:
287:
255:(4): 653â5.
252:
248:
209:
205:
201:
191:
187:
183:
178:
174:
170:
166:
163:M. africanum
162:
154:
148:
141:
137:
130:
123:
116:
109:
102:
95:
83:
76:
69:
62:
57:
53:tuberculosis
46:
42:
38:
32:
31:
29:
1987:M. bolletii
1959:M. chelonae
1848:M. pulveris
1636:M. septicum
1619:M. porcinum
1520:M. neoaurum
1412:M. triviale
1343:M. palustre
1293:M. parmense
1222:M. arupense
1175:M. branderi
1055:M. gordonae
923:M. kansasii
890:M. chimaera
766:M. shottsii
759:M. ulcerans
698:M. canettii
605:(including
520:(1): 3994.
2089:Categories
1827:M. duvalii
1718:M. sphagni
1677:M. obuense
1548:F/T groups
1506:M. hodleri
1426:M. tusciae
1419:M. doricum
1349:M. kubicae
1267:M. triplex
1182:M. celatum
998:M. szulgai
841:K/H groups
733:M. marinum
691:M. microti
227:References
1939:M. murale
1914:M. goodii
1877:M. brumae
1767:M. vaccae
1683:M. gilvum
1575:M. gadium
1569:M. fallax
1563:M. chitae
1453:Runyon IV
1404:Ungrouped
1300:M. simiae
1202:M. terrae
1161:M. cookii
1124:M. xenopi
935:M. gastri
791:M. leprae
705:M. caprae
431:2571-5135
415:(4): 31.
171:M. caprae
1883:M. phlei
1753:M. aurum
1648:M. alvei
879:M. avium
872:M. avium
822:M. lacus
677:M. bovis
552:31488832
490:29205127
449:30279355
387:20350321
336:28186336
279:22469053
215:See also
184:M. bovis
167:M. bovis
88:and the
1814:M. agri
1096:(other)
784:Leprosy
648:(TKHGC)
543:6728331
522:Bibcode
440:6306742
378:2859774
327:5413830
306:Bibcode
270:3309669
35:complex
881:subp.
817:other
550:
540:
488:
447:
437:
429:
385:
375:
361:: 80.
334:
324:
277:
267:
92:strain
2040:This
192:bovis
190:var.
159:IJSEM
2046:stub
1338:R2S
1326:R3N
1307:R2S
1256:R3N
1073:R2S
1005:R3N
993:R2S
963:R3N
944:R2S
930:R3N
918:R1P
897:R2S
861:R3N
740:R2S
635:R3N=
629:R2S=
548:PMID
486:PMID
445:PMID
427:ISSN
383:PMID
332:PMID
275:PMID
43:MTBC
30:The
1169:R3N
1155:R2S
1049:R2S
1035:R1P
856:MAC
813:R3N
753:R3N
727:R1P
721:MPM
663:MTC
538:PMC
530:doi
476:doi
435:PMC
417:doi
373:PMC
363:doi
322:PMC
314:doi
265:PMC
257:doi
41:or
39:MTC
2091::
1747:AV
913:GK
623:P=
621:R1
546:.
536:.
528:.
518:10
516:.
512:.
498:^
484:.
472:68
470:.
466:.
443:.
433:.
425:.
411:.
407:.
395:^
381:.
371:.
359:10
357:.
353:.
330:.
320:.
312:.
302:86
300:.
296:.
273:.
263:.
253:18
251:.
247:.
235:^
173:,
169:,
165:,
2077:e
2070:t
2063:v
2052:.
1942:/
1911:/
1896:/
1880:/
1874:/
1857:/
1851:/
1830:/
1817:/
1735:/
1729:/
1715:/
1702:/
1686:/
1680:/
1645:/
1639:/
1622:/
1616:/
1610:/
1604:/
1572:/
1566:/
1450:/
1346:/
1290:/
1277:/
1264:/
1219:/
1121:/
869:/
639:)
633:;
627:;
619:(
609:)
595:e
588:t
581:v
565:.
554:.
532::
524::
492:.
478::
451:.
419::
413:7
389:.
365::
338:.
316::
308::
281:.
259::
37:(
20:)
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