307:
284:
181:
206:
313:
212:
1997:
52:
1210:
van de
Bovenkamp JH, Hau CM, Strous GJ, Buller HA, Dekker J, Einerhand AW (Jun 1998). "Molecular cloning of human gastric mucin MUC5AC reveals conserved cysteine-rich D-domains and a putative leucine zipper motif".
1260:
Samsuzzaman M, Uddin MS, Shah MA, Mathew B (August 2019). "Natural inhibitors on airway mucin: Molecular insight into the therapeutic potential targeting MUC5AC expression and production".
320:
219:
142:
747:
728:
1452:
1246:
2038:
2057:
1143:
1063:
1043:
1125:
1161:
Guyonnet
Duperat V, Audie JP, Debailleul V, Laine A, Buisine MP, Galiegue-Zouitina S, Pigny P, Degand P, Aubert JP, Porchet N (Feb 1995).
1829:
306:
958:
1869:
951:
283:
1719:
1112:
1091:
1034:. In the respiratory tract, it protects against infection by binding to inhaled pathogens, which are subsequently removed by
205:
180:
1108:
1087:
122:
1303:
Ehre C, Worthington EN, Liesman RM, Grubb BR, Barbier D, O'Neal WK, Sallenave JM, Pickles RJ, Boucher RC (2012-10-09).
1966:
1445:
319:
218:
2031:
1956:
312:
211:
1919:
1879:
1859:
1834:
796:
130:
49:
777:
773:
1430:
2067:
1894:
1438:
1163:"Characterization of the human mucin gene MUC5AC: a consensus cysteine-rich domain for 11p15 mucin genes?"
2024:
1035:
194:
1316:
1055:
109:
1899:
1824:
1711:
1688:
1652:
1624:
915:
868:
1849:
1372:"The Potential Role and Regulatory Mechanisms of MUC5AC in Chronic Obstructive Pulmonary Disease"
1285:
154:
889:
864:
1924:
1753:
1427:
provides an overview of all the structure information available in the PDB for Human Mucin-5AC
1403:
1352:
1334:
1277:
1228:
1192:
1059:
102:
42:
2008:
1839:
1656:
1609:
1393:
1383:
1342:
1324:
1269:
1220:
1182:
1174:
399:
330:
274:
229:
150:
2062:
1796:
1768:
1684:
374:
1320:
1946:
1465:
1398:
1371:
1347:
1304:
1187:
1162:
662:
657:
652:
636:
631:
626:
621:
616:
611:
606:
590:
2051:
1951:
1939:
1619:
1424:
1289:
577:
1305:"Overexpressing mouse model demonstrates the protective role of Muc5ac in the lungs"
1046:, and has also been associated with greater protection against influenza infection.
1864:
1776:
1643:
1473:
1469:
1031:
392:
171:
134:
158:
1976:
1971:
1961:
1934:
1904:
1889:
1758:
1614:
1604:
1481:
1148:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1130:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1309:
Proceedings of the
National Academy of Sciences of the United States of America
475:
1804:
1388:
1273:
291:
188:
138:
1338:
1914:
1909:
1884:
1874:
1786:
1329:
1088:
ENSG00000283158 GRCh38: Ensembl release 89: ENSG00000215182, ENSG00000283158
692:
535:
413:
358:
345:
257:
244:
146:
1407:
1356:
1281:
1224:
1232:
1196:
998:
993:
1733:
1728:
1723:
1701:
1696:
1674:
1669:
1629:
982:
822:
2004:
1781:
1664:
1461:
1017:
808:
759:
1996:
1178:
79:
75:
71:
1854:
1573:
1533:
1039:
966:
714:
1748:
1743:
1588:
1583:
1578:
1568:
1563:
1558:
1538:
1523:
1518:
1503:
1490:
677:
673:
1929:
1844:
1738:
1553:
1548:
1543:
1528:
1513:
1508:
1498:
1024:
126:
113:, MUC5, TBM, leB, mucin, mucin 5AC, oligomeric mucus/gel-forming
1434:
1038:. Overproduction of MUC-5AC can contribute to diseases such as
1247:"Entrez Gene: MUC5AC mucin 5AC, oligomeric mucus/gel-forming"
382:
2012:
547:
663:
stimulatory C-type lectin receptor signaling pathway
1817:
1795:
1767:
1710:
1683:
1651:
1642:
1597:
1489:
1480:
929:
908:
882:
857:
1104:
1102:
1100:
1083:
1081:
1079:
329:
228:
18:Protein-coding gene in the species Homo sapiens
1109:GRCm38: Ensembl release 89: ENSMUSG00000037974
2032:
1446:
8:
591:extracellular matrix structural constituent
2039:
2025:
1648:
1486:
1453:
1439:
1431:
688:
573:
370:
269:
166:
60:
1397:
1387:
1346:
1328:
1186:
1759:Structural maintenance of chromosomes 3
1075:
653:phosphatidylinositol-mediated signaling
20:
1064:chronic obstructive pulmonary disease
1044:chronic obstructive pulmonary disease
334:
295:
290:
233:
192:
187:
7:
1993:
1991:
2011:. You can help Knowledge (XXG) by
926:
905:
879:
854:
832:
813:
787:
764:
738:
719:
552:
470:
408:
387:
14:
1870:Cholesterylester transfer protein
1720:Chondroitin sulfate proteoglycans
1995:
1382:(19). Basel, Switzerland: 4437.
318:
311:
305:
282:
217:
210:
204:
179:
1030:MUC-5AC is a large gel-forming
536:More reference expression data
424:olfactory zone of nasal mucosa
1:
1370:Li J, Ye Z (September 2020).
1054:This gene has been linked to
303:
202:
2058:Genes on human chromosome 11
1967:Tumor necrosis factor alpha
2084:
1990:
1957:Thyroxine-binding proteins
1213:Biochem Biophys Res Commun
1920:Serum amyloid P component
1880:Colony-stimulating factor
1389:10.3390/molecules25194437
1274:10.1016/j.lfs.2019.05.041
1144:"Mouse PubMed Reference:"
1126:"Human PubMed Reference:"
997:
992:
988:
981:
965:
959:Chr 7: 141.34 – 141.37 Mb
946:
933:
912:
901:
886:
861:
850:
839:
835:
820:
816:
807:
794:
790:
771:
767:
758:
745:
741:
726:
722:
713:
698:
691:
687:
671:
576:
572:
560:
555:
546:
533:
510:quadriceps femoris muscle
482:
473:
420:
411:
381:
373:
369:
352:
339:
302:
281:
272:
268:
251:
238:
201:
178:
169:
165:
120:
117:
107:
100:
95:
68:
63:
46:
41:
36:
32:
28:
23:
1860:B-cell activating factor
1835:Alpha 1-antichymotrypsin
1330:10.1073/pnas.1206552109
1020:that is encoded by the
2007:-related article is a
1895:Membrane glycoproteins
1225:10.1006/bbrc.1998.8535
494:mucous cell of stomach
47:Human UniProt search:
1062:and is associated to
1036:mucociliary clearance
952:Chr 11: 1.16 – 1.2 Mb
622:extracellular exosome
490:epithelium of stomach
195:Chromosome 11 (human)
1056:mucus hypersecretion
617:extracellular region
506:olfactory epithelium
336:7 F5|7 87.23 cM
297:Chromosome 7 (mouse)
64:List of PDB id codes
37:Available structures
1900:Myelin protein zero
1825:Activin and inhibin
1625:Phytohaemagglutinin
1321:2012PNAS..10916528E
1315:(41): 16528–16533.
658:O-glycan processing
627:extracellular space
498:conjunctival fornix
448:islet of Langerhans
444:canal of the cervix
1850:Asialoglycoprotein
1050:Clinical relevance
797:ENSMUSG00000037974
646:Biological process
600:Cellular component
584:Molecular function
159:MUC5AC - orthologs
2020:
2019:
1985:
1984:
1925:Sialoglycoprotein
1813:
1812:
1754:Platelet factor 4
1638:
1637:
1179:10.1042/bj3050211
1060:respiratory tract
1008:
1007:
1004:
1003:
977:
976:
942:
941:
923:
922:
897:
896:
876:
875:
846:
845:
829:
828:
803:
802:
784:
783:
754:
753:
735:
734:
683:
682:
568:
567:
564:
563:
542:
541:
529:
528:
467:
466:
365:
364:
264:
263:
91:
90:
87:
86:
2075:
2041:
2034:
2027:
1999:
1992:
1840:Apolipoprotein H
1649:
1610:Intrinsic factor
1487:
1455:
1448:
1441:
1432:
1412:
1411:
1401:
1391:
1367:
1361:
1360:
1350:
1332:
1300:
1294:
1293:
1257:
1251:
1250:
1243:
1237:
1236:
1207:
1201:
1200:
1190:
1158:
1152:
1151:
1140:
1134:
1133:
1122:
1116:
1106:
1095:
1085:
990:
989:
961:
954:
937:
927:
918:
906:
902:RefSeq (protein)
892:
880:
871:
855:
833:
814:
788:
765:
739:
720:
689:
574:
553:
538:
478:
476:Top expressed in
471:
416:
414:Top expressed in
409:
388:
371:
361:
348:
337:
322:
315:
309:
298:
286:
270:
260:
247:
236:
221:
214:
208:
197:
183:
167:
161:
112:
105:
82:
61:
55:
34:
33:
21:
2083:
2082:
2078:
2077:
2076:
2074:
2073:
2072:
2048:
2047:
2046:
2045:
1988:
1986:
1981:
1809:
1791:
1763:
1706:
1679:
1634:
1593:
1476:
1459:
1421:
1416:
1415:
1369:
1368:
1364:
1302:
1301:
1297:
1259:
1258:
1254:
1245:
1244:
1240:
1209:
1208:
1204:
1173:(Pt 1): 211–9.
1160:
1159:
1155:
1142:
1141:
1137:
1124:
1123:
1119:
1107:
1098:
1086:
1077:
1072:
1052:
999:View/Edit Mouse
994:View/Edit Human
957:
950:
947:Location (UCSC)
935:
914:
888:
867:
863:
778:ENSG00000283158
776:
774:ENSG00000215182
667:
641:
632:plasma membrane
595:
534:
525:
520:
516:
512:
508:
504:
500:
496:
492:
488:
474:
463:
458:
456:urinary bladder
454:
450:
446:
442:
438:
434:
432:body of stomach
430:
426:
412:
356:
343:
335:
325:
324:
323:
316:
296:
273:Gene location (
255:
242:
234:
224:
223:
222:
215:
193:
170:Gene location (
121:
108:
101:
70:
48:
19:
12:
11:
5:
2081:
2079:
2071:
2070:
2065:
2060:
2050:
2049:
2044:
2043:
2036:
2029:
2021:
2018:
2017:
2000:
1983:
1982:
1980:
1979:
1974:
1969:
1964:
1959:
1954:
1949:
1947:Thrombopoietin
1944:
1943:
1942:
1937:
1932:
1922:
1917:
1912:
1907:
1902:
1897:
1892:
1887:
1882:
1877:
1872:
1867:
1862:
1857:
1852:
1847:
1842:
1837:
1832:
1827:
1821:
1819:
1815:
1814:
1811:
1810:
1808:
1807:
1801:
1799:
1793:
1792:
1790:
1789:
1784:
1779:
1773:
1771:
1765:
1764:
1762:
1761:
1756:
1751:
1746:
1741:
1736:
1731:
1726:
1716:
1714:
1708:
1707:
1705:
1704:
1699:
1693:
1691:
1681:
1680:
1678:
1677:
1672:
1667:
1661:
1659:
1646:
1640:
1639:
1636:
1635:
1633:
1632:
1627:
1622:
1617:
1612:
1607:
1601:
1599:
1595:
1594:
1592:
1591:
1586:
1581:
1576:
1571:
1566:
1561:
1556:
1551:
1546:
1541:
1536:
1531:
1526:
1521:
1516:
1511:
1506:
1501:
1495:
1493:
1484:
1478:
1477:
1466:glycoconjugate
1460:
1458:
1457:
1450:
1443:
1435:
1429:
1428:
1420:
1419:External links
1417:
1414:
1413:
1362:
1295:
1252:
1238:
1202:
1153:
1135:
1117:
1096:
1074:
1073:
1071:
1068:
1051:
1048:
1006:
1005:
1002:
1001:
996:
986:
985:
979:
978:
975:
974:
972:
970:
963:
962:
955:
948:
944:
943:
940:
939:
931:
930:
924:
921:
920:
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903:
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898:
895:
894:
884:
883:
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843:
837:
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826:
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811:
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792:
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785:
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781:
769:
768:
762:
756:
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751:
743:
742:
736:
733:
732:
724:
723:
717:
711:
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685:
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669:
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666:
665:
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655:
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629:
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619:
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587:
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581:
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569:
566:
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562:
561:
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543:
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539:
531:
530:
527:
526:
524:
523:
519:
515:
511:
507:
503:
499:
495:
491:
487:
486:pyloric antrum
483:
480:
479:
468:
465:
464:
462:
461:
457:
453:
449:
445:
441:
437:
433:
429:
428:gastric mucosa
425:
421:
418:
417:
405:
404:
396:
385:
379:
378:
375:RNA expression
367:
366:
363:
362:
354:
350:
349:
341:
338:
333:
327:
326:
317:
310:
304:
300:
299:
294:
288:
287:
279:
278:
266:
265:
262:
261:
253:
249:
248:
240:
237:
232:
226:
225:
216:
209:
203:
199:
198:
191:
185:
184:
176:
175:
163:
162:
119:
115:
114:
106:
98:
97:
93:
92:
89:
88:
85:
84:
66:
65:
57:
56:
45:
39:
38:
30:
29:
26:
25:
17:
13:
10:
9:
6:
4:
3:
2:
2080:
2069:
2068:Protein stubs
2066:
2064:
2061:
2059:
2056:
2055:
2053:
2042:
2037:
2035:
2030:
2028:
2023:
2022:
2016:
2014:
2010:
2006:
2001:
1998:
1994:
1989:
1978:
1975:
1973:
1970:
1968:
1965:
1963:
1960:
1958:
1955:
1953:
1952:Thyroglobulin
1950:
1948:
1945:
1941:
1940:Glycophorin C
1938:
1936:
1933:
1931:
1928:
1927:
1926:
1923:
1921:
1918:
1916:
1913:
1911:
1908:
1906:
1903:
1901:
1898:
1896:
1893:
1891:
1888:
1886:
1883:
1881:
1878:
1876:
1873:
1871:
1868:
1866:
1863:
1861:
1858:
1856:
1853:
1851:
1848:
1846:
1843:
1841:
1838:
1836:
1833:
1831:
1828:
1826:
1823:
1822:
1820:
1816:
1806:
1803:
1802:
1800:
1798:
1794:
1788:
1785:
1783:
1780:
1778:
1775:
1774:
1772:
1770:
1766:
1760:
1757:
1755:
1752:
1750:
1747:
1745:
1742:
1740:
1737:
1735:
1732:
1730:
1727:
1725:
1721:
1718:
1717:
1715:
1713:
1709:
1703:
1700:
1698:
1695:
1694:
1692:
1690:
1686:
1682:
1676:
1673:
1671:
1668:
1666:
1663:
1662:
1660:
1658:
1654:
1650:
1647:
1645:
1644:Proteoglycans
1641:
1631:
1628:
1626:
1623:
1621:
1620:Peptidoglycan
1618:
1616:
1613:
1611:
1608:
1606:
1603:
1602:
1600:
1596:
1590:
1587:
1585:
1582:
1580:
1577:
1575:
1572:
1570:
1567:
1565:
1562:
1560:
1557:
1555:
1552:
1550:
1547:
1545:
1542:
1540:
1537:
1535:
1532:
1530:
1527:
1525:
1522:
1520:
1517:
1515:
1512:
1510:
1507:
1505:
1502:
1500:
1497:
1496:
1494:
1492:
1488:
1485:
1483:
1479:
1475:
1474:glycopeptides
1471:
1470:glycoproteins
1467:
1463:
1456:
1451:
1449:
1444:
1442:
1437:
1436:
1433:
1426:
1423:
1422:
1418:
1409:
1405:
1400:
1395:
1390:
1385:
1381:
1377:
1373:
1366:
1363:
1358:
1354:
1349:
1344:
1340:
1336:
1331:
1326:
1322:
1318:
1314:
1310:
1306:
1299:
1296:
1291:
1287:
1283:
1279:
1275:
1271:
1267:
1263:
1262:Life Sciences
1256:
1253:
1248:
1242:
1239:
1234:
1230:
1226:
1222:
1218:
1214:
1206:
1203:
1198:
1194:
1189:
1184:
1180:
1176:
1172:
1168:
1164:
1157:
1154:
1149:
1145:
1139:
1136:
1131:
1127:
1121:
1118:
1114:
1110:
1105:
1103:
1101:
1097:
1093:
1089:
1084:
1082:
1080:
1076:
1069:
1067:
1065:
1061:
1057:
1049:
1047:
1045:
1041:
1037:
1033:
1028:
1027:in humans.
1026:
1023:
1019:
1015:
1012:
1000:
995:
991:
987:
984:
980:
973:
971:
968:
964:
960:
956:
953:
949:
945:
938:
932:
928:
925:
919:
917:
911:
907:
904:
900:
893:
891:
885:
881:
878:
872:
870:
866:
860:
856:
853:
851:RefSeq (mRNA)
849:
842:
838:
834:
831:
825:
824:
819:
815:
812:
810:
806:
799:
798:
793:
789:
786:
780:
779:
775:
770:
766:
763:
761:
757:
750:
749:
744:
740:
737:
731:
730:
725:
721:
718:
716:
712:
709:
706:
704:
701:
697:
694:
690:
686:
679:
675:
670:
664:
661:
659:
656:
654:
651:
650:
648:
645:
644:
638:
635:
633:
630:
628:
625:
623:
620:
618:
615:
613:
610:
608:
605:
604:
602:
599:
598:
592:
589:
588:
586:
583:
582:
579:
578:Gene ontology
575:
571:
559:
554:
551:
549:
545:
537:
532:
521:
517:
513:
509:
505:
501:
497:
493:
489:
485:
484:
481:
477:
472:
469:
460:muscle tissue
459:
455:
451:
447:
443:
439:
435:
431:
427:
423:
422:
419:
415:
410:
407:
406:
403:
401:
397:
395:
394:
390:
389:
386:
384:
380:
376:
372:
368:
360:
355:
351:
347:
342:
332:
328:
321:
314:
308:
301:
293:
289:
285:
280:
276:
271:
267:
259:
254:
250:
246:
241:
231:
227:
220:
213:
207:
200:
196:
190:
186:
182:
177:
173:
168:
164:
160:
156:
152:
148:
144:
140:
136:
132:
128:
124:
116:
111:
104:
99:
94:
83:
81:
77:
73:
67:
62:
59:
58:
54:
51:
44:
40:
35:
31:
27:
22:
16:
2013:expanding it
2002:
1987:
1865:4-1BB ligand
1777:Fibromodulin
1482:Mucoproteins
1379:
1375:
1365:
1312:
1308:
1298:
1265:
1261:
1255:
1241:
1219:(3): 853–9.
1216:
1212:
1205:
1170:
1166:
1156:
1147:
1138:
1129:
1120:
1053:
1032:glycoprotein
1029:
1021:
1013:
1010:
1009:
934:
916:NP_001291288
913:
887:
869:NM_001304359
862:
840:
821:
795:
772:
746:
727:
707:
702:
398:
391:
357:141,372,968
344:141,342,709
118:External IDs
69:
15:
1977:Vitronectin
1972:Uteroglobin
1962:Transcortin
1935:Glycophorin
1905:Osteonectin
1890:Lactoferrin
1615:Orosomucoid
1605:Haptoglobin
637:mucus layer
612:Golgi lumen
440:gallbladder
96:Identifiers
2052:Categories
1805:Syndecan 1
1268:: 116485.
1115:, May 2017
1094:, May 2017
1070:References
402:(ortholog)
256:1,201,138
243:1,157,953
139:HomoloGene
1915:Protein S
1910:Protein C
1885:Hemopexin
1875:Clusterin
1787:Keratocan
1376:Molecules
1339:1091-6490
1290:162182150
1167:Biochem J
1014:(MUC-5AC)
1011:Mucin-5AC
890:NM_010844
865:NM_017511
693:Orthologs
607:cytoplasm
514:esophagus
147:GeneCards
1734:Brevican
1729:Neurocan
1724:Aggrecan
1702:Perlecan
1697:Testican
1675:Versican
1670:Biglycan
1630:Ovomucin
1408:32992527
1357:23012413
1282:31116959
1111:–
1090:–
1066:(COPD).
983:Wikidata
672:Sources:
522:pancreas
502:duodenum
452:appendix
2005:protein
1782:Lumican
1665:Decorin
1462:Protein
1425:PDBe-KB
1399:7582261
1348:3478656
1317:Bibcode
1233:9588204
1197:7826332
1188:1136451
1113:Ensembl
1092:Ensembl
1058:in the
1018:protein
809:UniProt
760:Ensembl
699:Species
678:QuickGO
377:pattern
235:11p15.5
103:Aliases
2063:Mucins
1855:Avidin
1534:MUC5AC
1406:
1396:
1355:
1345:
1337:
1288:
1280:
1231:
1195:
1185:
1040:asthma
1022:MUC5AC
969:search
967:PubMed
823:P98088
715:Entrez
548:BioGPS
518:cornea
436:fundus
151:MUC5AC
143:137237
135:104697
127:158373
110:MUC5AC
24:MUC5AC
2003:This
1818:Other
1749:CSPG5
1744:CSPG4
1598:Other
1589:MUC20
1584:MUC19
1579:MUC17
1574:MUC16
1569:MUC15
1564:MUC13
1559:MUC12
1539:MUC5B
1524:MUC3B
1519:MUC3A
1504:CD164
1491:Mucin
1286:S2CID
1016:is a
748:17833
708:Mouse
703:Human
674:Amigo
400:Mouse
393:Human
340:Start
275:Mouse
239:Start
172:Human
2009:stub
1930:CD43
1845:CD70
1830:ADAM
1739:CD44
1554:MUC8
1549:MUC7
1544:MUC6
1529:MUC4
1514:MUC2
1509:MUC1
1499:CD43
1472:and
1404:PMID
1353:PMID
1335:ISSN
1278:PMID
1229:PMID
1193:PMID
1042:and
1025:gene
729:4586
383:Bgee
331:Band
292:Chr.
230:Band
189:Chr.
123:OMIM
80:5AJO
76:5AJP
72:5AJN
53:RCSB
50:PDBe
1394:PMC
1384:doi
1343:PMC
1325:doi
1313:109
1270:doi
1266:231
1221:doi
1217:245
1183:PMC
1175:doi
1171:305
936:n/a
841:n/a
556:n/a
353:End
252:End
155:OMA
131:MGI
43:PDB
2054::
1797:HS
1769:KS
1722::
1712:CS
1689:CS
1685:HS
1657:DS
1653:CS
1468::
1464:,
1402:.
1392:.
1380:25
1378:.
1374:.
1351:.
1341:.
1333:.
1323:.
1311:.
1307:.
1284:.
1276:.
1264:.
1227:.
1215:.
1191:.
1181:.
1169:.
1165:.
1146:.
1128:.
1099:^
1078:^
676:/
359:bp
346:bp
258:bp
245:bp
153:;
149::
145:;
141::
137:;
133::
129:;
125::
78:,
74:,
2040:e
2033:t
2026:v
2015:.
1687:/
1655:/
1454:e
1447:t
1440:v
1410:.
1386::
1359:.
1327::
1319::
1292:.
1272::
1249:.
1235:.
1223::
1199:.
1177::
1150:.
1132:.
277:)
174:)
157::
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