234:
211:
108:
133:
240:
139:
4161:
1198:(ERKs), and are involved in signaling cascades that regulate a number of cellular processes, including proliferation, differentiation, and transcriptional regulation. MAPK15 is often referred to as ERK7 or ERK8, and the latter two share 69% amino acid sequence similarity; at least one study has suggested that the two are, in fact, distinct proteins.
1267:
Due to its role in protecting genomic integrity and cell motility, MAPK15 has been identified as a potential target for cancer therapeutics. Additionally, given the putative role that MAPK15 plays in the regulation of ciliogenesis, it may be an ideal target for diseases related to human ciliary
1220:
with acetyl galactosamine (GalNAc), a process in which a sugar molecule is covalently attached to an oxygen atom on an amino acid residue. Mammalian MAPK15 is a putative regulator of the cellular localization and transcriptional activity of
1209:) that has been implicated in cancer growth and progression in humans when it is overexpressed. The exact function of MAPK15 is unknown, though a number of studies have implicated the enzyme in various cellular pathways.
2024:
2309:
1255:) and microtubule-associated proteins 1A/1B light chain 3A (MAP1LC3A, or LC3) in a process that stimulates autophagy. A number of additional proteins also interact with MAPK15, including
2017:
2010:
247:
146:
2217:
1205:
homology 3) binding motifs in its C-terminal region, and is likely activated by an SRC-dependent signaling pathway. SRC is a non-receptor tyrosine kinase (and
2765:
3604:
2068:
1487:"Extracellular signal-regulated kinase 8 (ERK8) controls estrogen-related receptor α (ERRα) cellular localization and inhibits its transcriptional activity"
3713:
2451:
2338:
1202:
854:
835:
69:
2726:
3699:
3164:
2055:
2037:
3801:
3682:
3388:
2257:
1348:
1330:
3452:
2427:
1195:
4181:
3708:
233:
2242:
1058:
3765:
3440:
1226:
1065:
210:
3880:
2697:
2687:
2372:
1783:"Activation of the Erk8 mitogen-activated protein (MAP) kinase by RET/PTC3, a constitutively active form of the RET proto-oncogene"
1415:
1216:, and MAPK15 down-regulation is correlated with increased cell motility. MAPK15 has also been found to negatively regulate protein
1634:
Colecchia D, Strambi A, Sanzone S, Iavarone C, Rossi M, Dall'Armi C, Piccioni F, Verrotti di
Pianella A, Chiariello M (Dec 2012).
3379:
1201:
In vertebrate models, ERK8 is not constitutively active, and exhibits relatively low basal kinase activity. It contains two SH3 (
3648:
3320:
2682:
2673:
1782:
1317:
1296:
1222:
4036:
1313:
132:
107:
3063:
2560:
2551:
2208:
2154:
1538:"A chromatin-bound kinase, ERK8, protects genomic integrity by inhibiting HDM2-mediated degradation of the DNA clamp PCNA"
1292:
4151:
2251:
1950:"Molecular cloning and characterization of a mitogen-activated protein kinase-associated intracellular chloride channel"
246:
145:
2002:
3275:
3093:
2589:
239:
138:
4021:
4137:
4124:
4111:
4098:
4085:
4072:
4059:
3265:
3260:
3255:
3245:
3240:
3235:
3225:
3020:
2795:
2391:
1256:
4031:
3985:
3928:
3488:
3479:
3430:
2196:
2041:
903:
57:
1781:
Iavarone C, Acunzo M, Carlomagno F, Catania A, Melillo RM, Carlomagno SM, Santoro M, Chiariello M (Apr 2006).
3933:
3788:
3211:
1166:
884:
880:
1872:"Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions"
1870:
Suzuki Y, Yamashita R, Shirota M, Sakakibara Y, Chiba J, Mizushima-Sugano J, Nakai K, Sugano S (Sep 2004).
1587:"ERK7 regulates ciliogenesis by phosphorylating the actin regulator CapZIP in cooperation with Dishevelled"
1485:
Rossi M, Colecchia D, Iavarone C, Strambi A, Piccioni F, Verrotti di
Pianella A, Chiariello M (Mar 2011).
1217:
1172:
1915:"gp120-mediated induction of the MAPK cascade is dependent on the activation state of CD4(+) lymphocytes"
3954:
3873:
2487:
4026:
1993:
3054:
1696:
1598:
1259:(CDK2), mitogen-activated protein kinase 12 (MAPK12), and lactotransferrin (LTF), among many others.
121:
44:
1233:, and is an essential factor in protecting genome stability. MAPK15 has also been shown to regulate
3990:
1251:
MAPK15 has been demonstrated to interact with gamma-aminobutyric acid receptor-associated protein (
3562:
4186:
3923:
3665:
3619:
1815:
81:
1683:
Strambi A, Mori M, Rossi M, Colecchia D, Manetti F, Carlomagno F, Botta M, Chiariello M (2013).
1041:
1020:
994:
973:
2925:
2634:
1971:
1936:
1901:
1858:
1807:
1769:
1724:
1665:
1616:
1567:
1518:
1467:
1392:
1154:
37:
3969:
3964:
3938:
3866:
3518:
2760:
2750:
2745:
2663:
2654:
2584:
2575:
2521:
2512:
2169:
1961:
1926:
1891:
1883:
1848:
1840:
1797:
1759:
1714:
1704:
1655:
1647:
1606:
1557:
1549:
1508:
1498:
1457:
1447:
1382:
1369:
Abe MK, Saelzler MP, Espinosa R, Kahle KT, Hershenson MB, Le Beau MM, Rosner MR (May 2002).
326:
257:
201:
156:
77:
4016:
4000:
3913:
3344:
2415:
2410:
2405:
1997:
1230:
1136:
301:
1700:
1602:
4165:
4054:
3995:
1853:
1828:
1719:
1684:
1660:
1635:
1562:
1537:
1513:
1486:
1462:
1435:
1239:
1206:
1178:
1896:
1871:
769:
764:
759:
754:
749:
744:
739:
734:
729:
724:
719:
714:
709:
704:
699:
694:
689:
684:
679:
674:
658:
653:
648:
643:
638:
633:
628:
623:
618:
613:
608:
603:
598:
593:
588:
583:
578:
562:
557:
552:
547:
542:
537:
532:
527:
522:
517:
4175:
3959:
3918:
2468:
2400:
504:
1819:
61:
3908:
3339:
2164:
1269:
1243:(African clawed frog) embryos by phosphorylating an actin regulator called CapZIP.
1234:
1148:
319:
98:
1748:"ERK8 down-regulates transactivation of the glucocorticoid receptor through Hic-5"
1212:
Specifically, MAPK15 expression is significantly reduced in human lung and breast
1709:
85:
4132:
4067:
3903:
3545:
3177:
3117:
3000:
2920:
2644:
1353:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1335:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1160:
4160:
1931:
1914:
1636:"MAPK15/ERK8 stimulates autophagy by interacting with LC3 and GABARAP proteins"
402:
3633:
2107:
1827:
Klevernic IV, Stafford MJ, Morrice N, Peggie M, Morton S, Cohen P (Feb 2006).
1191:
1142:
218:
115:
65:
1913:
Kinet S, Bernard F, Mongellaz C, Perreau M, Goldman FD, Taylor N (Oct 2002).
4106:
4080:
2594:
1746:
Saelzler MP, Spackman CC, Liu Y, Martinez LC, Harris JP, Abe MK (Jun 2006).
1503:
1293:
ENSG00000274205 GRCh38: Ensembl release 89: ENSG00000181085, ENSG00000274205
1213:
799:
462:
340:
285:
272:
184:
171:
73:
1966:
1949:
1940:
1905:
1862:
1829:"Characterization of the reversible phosphorylation and activation of ERK8"
1811:
1802:
1773:
1764:
1747:
1728:
1669:
1620:
1571:
1522:
1471:
1436:"ERK8 is a negative regulator of O-GalNAc glycosylation and cell migration"
1396:
1387:
1370:
1975:
1553:
1105:
1100:
2950:
2845:
2840:
2835:
1194:(mitogen-activated protein) kinase family. MAP kinases are also known as
1089:
948:
929:
1452:
3609:
3587:
3582:
3572:
3567:
3369:
3364:
3359:
3354:
3349:
3334:
3329:
2980:
2945:
2184:
2179:
2174:
1887:
1844:
1651:
1611:
1586:
1252:
915:
866:
1134:
Evolutionarily, MAPK15 is conserved in a number of species, including
4119:
3889:
3839:
3834:
3829:
3824:
3819:
3814:
3809:
3760:
3755:
3750:
3745:
3740:
3723:
3718:
3592:
3577:
3528:
3523:
3508:
3503:
3498:
3493:
3467:
3462:
3457:
3445:
3418:
3310:
3285:
2960:
2785:
2780:
2775:
2770:
2755:
2599:
2536:
2531:
2526:
2502:
2328:
2323:
2297:
2292:
2287:
2277:
2272:
2262:
2102:
2033:
1121:
1073:
821:
1371:"ERK8, a new member of the mitogen-activated protein kinase family"
4093:
3735:
3728:
3638:
3535:
3435:
3413:
3408:
3403:
3398:
3393:
3305:
3300:
3295:
3290:
3280:
3250:
3230:
3107:
3102:
3083:
3078:
3068:
3044:
3039:
3034:
3010:
3005:
2995:
2990:
2985:
2975:
2955:
2940:
2935:
2930:
2910:
2905:
2895:
2890:
2885:
2880:
2875:
2865:
2860:
2855:
2850:
2830:
2825:
2820:
2815:
2810:
2805:
2790:
2740:
2735:
2629:
2624:
2619:
2614:
2609:
2604:
2565:
2497:
2492:
2441:
2436:
2362:
2357:
2352:
2318:
2310:
3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase
2112:
2097:
2092:
2087:
2082:
2077:
784:
780:
750:
positive regulation of metaphase/anaphase transition of meiosis I
3628:
3555:
3550:
3540:
3513:
3270:
3220:
3201:
3196:
3191:
3186:
3141:
3136:
3131:
3126:
3073:
3029:
2970:
2965:
2915:
2900:
2870:
2800:
2716:
2711:
2706:
2639:
2541:
2482:
2477:
2381:
2347:
2232:
2227:
2222:
2191:
2159:
2147:
2142:
2137:
2127:
2122:
1128:
3862:
3786:
3162:
2053:
2006:
1685:"Structure prediction and validation of the ERK8 kinase domain"
3597:
2132:
2117:
1990:
1434:
Chia J, Tham KM, Gill DJ, Bard-Chapeau EA, Bard FA (2014).
3858:
685:
positive regulation of telomere maintenance via telomerase
1416:"Entrez Gene: MAPK15 mitogen-activated protein kinase 15"
309:
1585:
Miyatake K, Kusakabe M, Takahashi C, Nishida E (2015).
4149:
474:
1190:
The protein encoded by this gene is a member of the
765:
positive regulation of cell population proliferation
4045:
4009:
3978:
3947:
3896:
3800:
3698:
3681:
3664:
3647:
3618:
3478:
3378:
3319:
3210:
3176:
3116:
3092:
3053:
3019:
2725:
2696:
2672:
2653:
2574:
2550:
2511:
2467:
2450:
2426:
2390:
2371:
2337:
2308:
2241:
2207:
2067:
1034:
1013:
987:
966:
1309:
1307:
1305:
1288:
1286:
1284:
1948:Qian Z, Okuhara D, Abe MK, Rosner MR (Jan 1999).
256:
155:
48:, ERK7, ERK8, mitogen-activated protein kinase 15
720:protein localization to ciliary transition zone
16:Protein-coding gene in the species Homo sapiens
1364:
1362:
1314:GRCm38: Ensembl release 89: ENSMUSG00000063704
3874:
2069:Non-specific serine/threonine protein kinases
2018:
1120:, also known as MAPK15, ERK7, or ERK8, is an
8:
1429:
1427:
1425:
3881:
3867:
3859:
3797:
3783:
3173:
3159:
2452:Goodpasture-antigen-binding protein kinase
2064:
2050:
2025:
2011:
2003:
795:
695:positive regulation of telomerase activity
500:
297:
196:
93:
3165:Serine/threonine-specific protein kinases
2339:(isocitrate dehydrogenase (NADP+)) kinase
2056:Serine/threonine-specific protein kinases
2038:Serine/threonine-specific protein kinases
1965:
1930:
1895:
1852:
1801:
1763:
1718:
1708:
1659:
1610:
1561:
1512:
1502:
1461:
1451:
1386:
1229:(PCNA) degradation. PCNA is critical for
3700:Receptor protein serine/threonine kinase
1410:
1408:
1406:
760:cellular response to DNA damage stimulus
538:protein serine/threonine kinase activity
4156:
3683:Low-density-lipoprotein receptor kinase
1280:
755:positive regulation of spindle assembly
675:positive regulation of telomere capping
1196:extracellular signal-regulated kinases
18:
2428:Fas-activated serine/threonine kinase
1536:Groehler AL, Lannigan DA (Aug 2010).
735:negative regulation of cell migration
261:
222:
217:
160:
119:
114:
7:
3709:Bone morphogenetic protein receptors
2243:Dephospho-(reductase kinase) kinase
1954:The Journal of Biological Chemistry
1790:The Journal of Biological Chemistry
1752:The Journal of Biological Chemistry
1491:The Journal of Biological Chemistry
1375:The Journal of Biological Chemistry
1225:(ERRa), as well as an inhibitor of
1118:Mitogen-activated protein kinase 15
725:regulation of COPII vesicle coating
2698:G-protein coupled receptor kinases
1227:proliferating cell nuclear antigen
1031:
1010:
984:
963:
939:
920:
894:
871:
845:
826:
730:endoplasmic reticulum organization
579:intracellular anatomical structure
479:
397:
335:
314:
14:
2688:Beta adrenergic receptor kinase-2
2373:(tyrosine 3-monooxygenase) kinase
1124:that in humans is encoded by the
770:intracellular signal transduction
4159:
3380:Mitogen-activated protein kinase
245:
238:
232:
209:
144:
137:
131:
106:
3766:Anti-Müllerian hormone receptor
3649:(acetyl-CoA carboxylase) kinase
3321:(RNA-polymerase)-subunit kinase
2683:Beta adrenergic receptor kinase
2674:Beta adrenergic receptor kinase
1223:estrogen-related receptor alpha
3389:Extracellular signal-regulated
463:More reference expression data
355:olfactory zone of nasal mucosa
1:
3453:P38 mitogen-activated protein
2552:cGMP-dependent protein kinase
2513:cAMP-dependent protein kinase
2209:Pyruvate dehydrogenase kinase
2155:Ataxia telangiectasia mutated
745:regulation of cilium assembly
710:regulation of gene expression
230:
129:
2252:AMP-activated protein kinase
1710:10.1371/journal.pone.0052011
4182:Genes on human chromosome 8
3167:(EC 2.7.11.21-EC 2.7.11.30)
1542:The Journal of Cell Biology
705:protein autophosphorylation
375:right lobe of thyroid gland
4203:
3094:Elongation factor 2 kinase
2058:(EC 2.7.11.1-EC 2.7.11.20)
1932:10.1182/blood-2002-03-0819
367:left lobe of thyroid gland
4037:Michaelis–Menten kinetics
3796:
3782:
3489:MAP kinase kinase kinases
3172:
3158:
3021:Myosin light-chain kinase
2727:Ca2+/calmodulin-dependent
2392:Myosin-heavy-chain kinase
2063:
2049:
1349:"Mouse PubMed Reference:"
1331:"Human PubMed Reference:"
1257:cyclin-dependent kinase 2
1104:
1099:
1095:
1088:
1072:
1059:Chr 8: 143.72 – 143.72 Mb
1053:
1038:
1017:
1006:
991:
970:
959:
946:
942:
927:
923:
914:
901:
897:
878:
874:
865:
852:
848:
833:
829:
820:
805:
798:
794:
778:
644:bicellular tight junction
503:
499:
487:
482:
473:
460:
409:
400:
347:
338:
308:
300:
296:
279:
266:
229:
208:
199:
195:
178:
165:
128:
105:
96:
92:
55:
52:
42:
35:
30:
26:
21:
3929:Diffusion-limited enzyme
3789:Dual-specificity kinases
1066:Chr 15: 75.87 – 75.87 Mb
3212:Cyclin-dependent kinase
1833:The Biochemical Journal
1504:10.1074/jbc.M110.179523
715:regulation of autophagy
690:protein phosphorylation
553:protein kinase activity
1967:10.1074/jbc.274.3.1621
1803:10.1074/jbc.M513397200
1765:10.1074/jbc.M512418200
1388:10.1074/jbc.M112483200
1268:defects (often called
4022:Eadie–Hofstee diagram
3955:Allosteric regulation
1591:Nature Communications
1554:10.1083/jcb.201002124
1263:Clinical significance
224:Chromosome 15 (mouse)
4032:Lineweaver–Burk plot
3055:Phosphorylase kinase
584:extracellular region
518:transferase activity
122:Chromosome 8 (human)
1991:MAP Kinase Resource
1701:2013PLoSO...852011S
1603:2015NatCo...6.6666M
1453:10.7554/eLife.01828
654:cytoplasmic vesicle
533:MAP kinase activity
441:islet of Langerhans
433:seminiferous tubule
3991:Enzyme superfamily
3924:Enzyme promiscuity
3666:Tropomyosin kinase
3620:Tau-protein kinase
1996:2021-04-15 at the
1888:10.1101/gr.2435604
1845:10.1042/BJ20051288
1652:10.4161/auto.21857
1612:10.1038/ncomms7666
904:ENSMUSG00000063704
668:Biological process
619:ciliary basal body
609:cell-cell junction
572:Cellular component
528:SH3 domain binding
523:nucleotide binding
511:Molecular function
383:anterior pituitary
351:right uterine tube
86:MAPK15 - orthologs
4147:
4146:
3856:
3855:
3852:
3851:
3848:
3847:
3778:
3777:
3774:
3773:
3154:
3153:
3150:
3149:
2635:Protein kinase N1
2590:Protein kinase Cζ
1115:
1114:
1111:
1110:
1084:
1083:
1049:
1048:
1028:
1027:
1002:
1001:
981:
980:
955:
954:
936:
935:
910:
909:
891:
890:
861:
860:
842:
841:
790:
789:
563:chromatin binding
495:
494:
491:
490:
469:
468:
456:
455:
417:choroidal fissure
394:
393:
371:left uterine tube
292:
291:
191:
190:
4194:
4164:
4163:
4155:
4027:Hanes–Woolf plot
3970:Enzyme activator
3965:Enzyme inhibitor
3939:Enzyme catalysis
3883:
3876:
3869:
3860:
3798:
3784:
3431:C-Jun N-terminal
3174:
3160:
2664:Rhodopsin kinase
2655:Rhodopsin kinase
2585:Protein kinase C
2576:Protein kinase C
2561:Protein kinase G
2522:Protein kinase A
2133:Protein kinase B
2065:
2051:
2027:
2020:
2013:
2004:
1979:
1969:
1944:
1934:
1909:
1899:
1866:
1856:
1839:(Pt 1): 365–73.
1823:
1805:
1796:(15): 10567–76.
1787:
1777:
1767:
1758:(24): 16821–32.
1733:
1732:
1722:
1712:
1680:
1674:
1673:
1663:
1631:
1625:
1624:
1614:
1582:
1576:
1575:
1565:
1533:
1527:
1526:
1516:
1506:
1482:
1476:
1475:
1465:
1455:
1431:
1420:
1419:
1412:
1401:
1400:
1390:
1381:(19): 16733–43.
1366:
1357:
1356:
1345:
1339:
1338:
1327:
1321:
1311:
1300:
1290:
1097:
1096:
1068:
1061:
1044:
1032:
1023:
1011:
1007:RefSeq (protein)
997:
985:
976:
964:
940:
921:
895:
872:
846:
827:
796:
501:
480:
465:
405:
403:Top expressed in
398:
343:
341:Top expressed in
336:
315:
298:
288:
275:
264:
249:
242:
236:
225:
213:
197:
187:
174:
163:
148:
141:
135:
124:
110:
94:
88:
47:
40:
19:
4202:
4201:
4197:
4196:
4195:
4193:
4192:
4191:
4172:
4171:
4170:
4158:
4150:
4148:
4143:
4055:Oxidoreductases
4041:
4017:Enzyme kinetics
4005:
4001:List of enzymes
3974:
3943:
3914:Catalytic triad
3892:
3887:
3857:
3844:
3792:
3770:
3694:
3677:
3660:
3643:
3614:
3474:
3374:
3345:P70-S6 Kinase 1
3315:
3206:
3168:
3146:
3112:
3088:
3049:
3015:
2721:
2692:
2668:
2649:
2570:
2546:
2507:
2463:
2446:
2422:
2416:Aurora C kinase
2411:Aurora B kinase
2406:Aurora A kinase
2386:
2367:
2333:
2304:
2237:
2203:
2059:
2045:
2031:
1998:Wayback Machine
1987:
1982:
1947:
1912:
1876:Genome Research
1869:
1826:
1785:
1780:
1745:
1741:
1739:Further reading
1736:
1682:
1681:
1677:
1646:(12): 1724–40.
1633:
1632:
1628:
1584:
1583:
1579:
1535:
1534:
1530:
1497:(10): 8507–22.
1484:
1483:
1479:
1433:
1432:
1423:
1414:
1413:
1404:
1368:
1367:
1360:
1347:
1346:
1342:
1329:
1328:
1324:
1312:
1303:
1291:
1282:
1278:
1265:
1249:
1231:DNA replication
1218:O-glycosylation
1188:
1167:D. melanogaster
1106:View/Edit Mouse
1101:View/Edit Human
1064:
1057:
1054:Location (UCSC)
1040:
1019:
993:
972:
885:ENSG00000274205
883:
881:ENSG00000181085
774:
740:dopamine uptake
680:phosphorylation
663:
659:cell projection
629:meiotic spindle
624:Golgi apparatus
567:
558:kinase activity
543:protein binding
461:
452:
447:
443:
439:
437:proximal tubule
435:
431:
427:
423:
419:
415:
401:
390:
387:skin of abdomen
385:
381:
377:
373:
369:
365:
361:
357:
353:
339:
283:
270:
262:
252:
251:
250:
243:
223:
200:Gene location (
182:
169:
161:
151:
150:
149:
142:
120:
97:Gene location (
56:
43:
36:
17:
12:
11:
5:
4200:
4198:
4190:
4189:
4184:
4174:
4173:
4169:
4168:
4145:
4144:
4142:
4141:
4128:
4115:
4102:
4089:
4076:
4063:
4049:
4047:
4043:
4042:
4040:
4039:
4034:
4029:
4024:
4019:
4013:
4011:
4007:
4006:
4004:
4003:
3998:
3993:
3988:
3982:
3980:
3979:Classification
3976:
3975:
3973:
3972:
3967:
3962:
3957:
3951:
3949:
3945:
3944:
3942:
3941:
3936:
3931:
3926:
3921:
3916:
3911:
3906:
3900:
3898:
3894:
3893:
3888:
3886:
3885:
3878:
3871:
3863:
3854:
3853:
3850:
3849:
3846:
3845:
3843:
3842:
3837:
3832:
3827:
3822:
3817:
3812:
3806:
3804:
3794:
3793:
3787:
3780:
3779:
3776:
3775:
3772:
3771:
3769:
3768:
3763:
3758:
3753:
3748:
3743:
3738:
3733:
3732:
3731:
3726:
3721:
3716:
3705:
3703:
3702:(EC 2.7.11.30)
3696:
3695:
3693:
3692:
3688:
3686:
3685:(EC 2.7.11.29)
3679:
3678:
3676:
3675:
3671:
3669:
3668:(EC 2.7.11.28)
3662:
3661:
3659:
3658:
3654:
3652:
3651:(EC 2.7.11.27)
3645:
3644:
3642:
3641:
3636:
3631:
3625:
3623:
3622:(EC 2.7.11.26)
3616:
3615:
3613:
3612:
3607:
3602:
3601:
3600:
3595:
3590:
3585:
3580:
3575:
3570:
3560:
3559:
3558:
3553:
3548:
3543:
3533:
3532:
3531:
3526:
3521:
3516:
3511:
3506:
3501:
3496:
3485:
3483:
3482:(EC 2.7.11.25)
3476:
3475:
3473:
3472:
3471:
3470:
3465:
3460:
3450:
3449:
3448:
3443:
3438:
3428:
3427:
3426:
3421:
3416:
3411:
3406:
3401:
3396:
3385:
3383:
3382:(EC 2.7.11.24)
3376:
3375:
3373:
3372:
3367:
3362:
3357:
3352:
3347:
3342:
3337:
3332:
3326:
3324:
3323:(EC 2.7.11.23)
3317:
3316:
3314:
3313:
3308:
3303:
3298:
3293:
3288:
3283:
3278:
3273:
3268:
3263:
3258:
3253:
3248:
3243:
3238:
3233:
3228:
3223:
3217:
3215:
3214:(EC 2.7.11.22)
3208:
3207:
3205:
3204:
3199:
3194:
3189:
3183:
3181:
3180:(EC 2.7.11.21)
3170:
3169:
3163:
3156:
3155:
3152:
3151:
3148:
3147:
3145:
3144:
3139:
3134:
3129:
3123:
3121:
3120:(EC 2.7.11.21)
3114:
3113:
3111:
3110:
3105:
3099:
3097:
3096:(EC 2.7.11.20)
3090:
3089:
3087:
3086:
3081:
3076:
3071:
3066:
3060:
3058:
3057:(EC 2.7.11.19)
3051:
3050:
3048:
3047:
3042:
3037:
3032:
3026:
3024:
3023:(EC 2.7.11.18)
3017:
3016:
3014:
3013:
3008:
3003:
2998:
2993:
2988:
2983:
2978:
2973:
2968:
2963:
2958:
2953:
2948:
2943:
2938:
2933:
2928:
2923:
2918:
2913:
2908:
2903:
2898:
2893:
2888:
2883:
2878:
2873:
2868:
2863:
2858:
2853:
2848:
2843:
2838:
2833:
2828:
2823:
2818:
2813:
2808:
2803:
2798:
2793:
2788:
2783:
2778:
2773:
2768:
2763:
2758:
2753:
2748:
2743:
2738:
2732:
2730:
2729:(EC 2.7.11.17)
2723:
2722:
2720:
2719:
2714:
2709:
2703:
2701:
2700:(EC 2.7.11.16)
2694:
2693:
2691:
2690:
2685:
2679:
2677:
2676:(EC 2.7.11.15)
2670:
2669:
2667:
2666:
2660:
2658:
2657:(EC 2.7.11.14)
2651:
2650:
2648:
2647:
2642:
2637:
2632:
2627:
2622:
2617:
2612:
2607:
2602:
2597:
2592:
2587:
2581:
2579:
2578:(EC 2.7.11.13)
2572:
2571:
2569:
2568:
2563:
2557:
2555:
2554:(EC 2.7.11.12)
2548:
2547:
2545:
2544:
2539:
2534:
2529:
2524:
2518:
2516:
2515:(EC 2.7.11.11)
2509:
2508:
2506:
2505:
2500:
2495:
2490:
2485:
2480:
2474:
2472:
2471:(EC 2.7.11.10)
2465:
2464:
2462:
2461:
2457:
2455:
2448:
2447:
2445:
2444:
2439:
2433:
2431:
2424:
2423:
2421:
2420:
2419:
2418:
2413:
2408:
2397:
2395:
2388:
2387:
2385:
2384:
2378:
2376:
2369:
2368:
2366:
2365:
2360:
2355:
2350:
2344:
2342:
2335:
2334:
2332:
2331:
2326:
2321:
2315:
2313:
2306:
2305:
2303:
2302:
2301:
2300:
2295:
2290:
2282:
2281:
2280:
2275:
2267:
2266:
2265:
2260:
2248:
2246:
2239:
2238:
2236:
2235:
2230:
2225:
2220:
2214:
2212:
2205:
2204:
2202:
2201:
2200:
2199:
2189:
2188:
2187:
2182:
2177:
2172:
2162:
2157:
2152:
2151:
2150:
2145:
2140:
2130:
2125:
2120:
2115:
2110:
2105:
2100:
2095:
2090:
2085:
2080:
2074:
2072:
2061:
2060:
2054:
2047:
2046:
2032:
2030:
2029:
2022:
2015:
2007:
2001:
2000:
1986:
1985:External links
1983:
1981:
1980:
1945:
1925:(7): 2546–53.
1910:
1867:
1824:
1778:
1742:
1740:
1737:
1735:
1734:
1675:
1626:
1577:
1528:
1477:
1421:
1402:
1358:
1340:
1322:
1301:
1279:
1277:
1274:
1264:
1261:
1248:
1245:
1207:proto-oncogene
1187:
1184:
1137:P. troglodytes
1113:
1112:
1109:
1108:
1103:
1093:
1092:
1086:
1085:
1082:
1081:
1079:
1077:
1070:
1069:
1062:
1055:
1051:
1050:
1047:
1046:
1036:
1035:
1029:
1026:
1025:
1015:
1014:
1008:
1004:
1003:
1000:
999:
989:
988:
982:
979:
978:
968:
967:
961:
957:
956:
953:
952:
944:
943:
937:
934:
933:
925:
924:
918:
912:
911:
908:
907:
899:
898:
892:
889:
888:
876:
875:
869:
863:
862:
859:
858:
850:
849:
843:
840:
839:
831:
830:
824:
818:
817:
812:
807:
803:
802:
792:
791:
788:
787:
776:
775:
773:
772:
767:
762:
757:
752:
747:
742:
737:
732:
727:
722:
717:
712:
707:
702:
697:
692:
687:
682:
677:
671:
669:
665:
664:
662:
661:
656:
651:
646:
641:
636:
631:
626:
621:
616:
611:
606:
601:
596:
591:
586:
581:
575:
573:
569:
568:
566:
565:
560:
555:
550:
545:
540:
535:
530:
525:
520:
514:
512:
508:
507:
497:
496:
493:
492:
489:
488:
485:
484:
477:
471:
470:
467:
466:
458:
457:
454:
453:
451:
450:
446:
442:
438:
434:
430:
426:
422:
418:
414:
410:
407:
406:
395:
392:
391:
389:
388:
384:
380:
376:
372:
368:
364:
360:
356:
352:
348:
345:
344:
332:
331:
323:
312:
306:
305:
302:RNA expression
294:
293:
290:
289:
281:
277:
276:
268:
265:
260:
254:
253:
244:
237:
231:
227:
226:
221:
215:
214:
206:
205:
193:
192:
189:
188:
180:
176:
175:
167:
164:
159:
153:
152:
143:
136:
130:
126:
125:
118:
112:
111:
103:
102:
90:
89:
54:
50:
49:
41:
33:
32:
28:
27:
24:
23:
15:
13:
10:
9:
6:
4:
3:
2:
4199:
4188:
4185:
4183:
4180:
4179:
4177:
4167:
4162:
4157:
4153:
4139:
4135:
4134:
4129:
4126:
4122:
4121:
4116:
4113:
4109:
4108:
4103:
4100:
4096:
4095:
4090:
4087:
4083:
4082:
4077:
4074:
4070:
4069:
4064:
4061:
4057:
4056:
4051:
4050:
4048:
4044:
4038:
4035:
4033:
4030:
4028:
4025:
4023:
4020:
4018:
4015:
4014:
4012:
4008:
4002:
3999:
3997:
3996:Enzyme family
3994:
3992:
3989:
3987:
3984:
3983:
3981:
3977:
3971:
3968:
3966:
3963:
3961:
3960:Cooperativity
3958:
3956:
3953:
3952:
3950:
3946:
3940:
3937:
3935:
3932:
3930:
3927:
3925:
3922:
3920:
3919:Oxyanion hole
3917:
3915:
3912:
3910:
3907:
3905:
3902:
3901:
3899:
3895:
3891:
3884:
3879:
3877:
3872:
3870:
3865:
3864:
3861:
3841:
3838:
3836:
3833:
3831:
3828:
3826:
3823:
3821:
3818:
3816:
3813:
3811:
3808:
3807:
3805:
3803:
3799:
3795:
3790:
3785:
3781:
3767:
3764:
3762:
3759:
3757:
3754:
3752:
3749:
3747:
3744:
3742:
3739:
3737:
3734:
3730:
3727:
3725:
3722:
3720:
3717:
3715:
3712:
3711:
3710:
3707:
3706:
3704:
3701:
3697:
3690:
3689:
3687:
3684:
3680:
3673:
3672:
3670:
3667:
3663:
3656:
3655:
3653:
3650:
3646:
3640:
3637:
3635:
3632:
3630:
3627:
3626:
3624:
3621:
3617:
3611:
3608:
3606:
3603:
3599:
3596:
3594:
3591:
3589:
3586:
3584:
3581:
3579:
3576:
3574:
3571:
3569:
3566:
3565:
3564:
3561:
3557:
3554:
3552:
3549:
3547:
3544:
3542:
3539:
3538:
3537:
3534:
3530:
3527:
3525:
3522:
3520:
3517:
3515:
3512:
3510:
3507:
3505:
3502:
3500:
3497:
3495:
3492:
3491:
3490:
3487:
3486:
3484:
3481:
3477:
3469:
3466:
3464:
3461:
3459:
3456:
3455:
3454:
3451:
3447:
3444:
3442:
3439:
3437:
3434:
3433:
3432:
3429:
3425:
3422:
3420:
3417:
3415:
3412:
3410:
3407:
3405:
3402:
3400:
3397:
3395:
3392:
3391:
3390:
3387:
3386:
3384:
3381:
3377:
3371:
3368:
3366:
3363:
3361:
3358:
3356:
3353:
3351:
3348:
3346:
3343:
3341:
3338:
3336:
3333:
3331:
3328:
3327:
3325:
3322:
3318:
3312:
3309:
3307:
3304:
3302:
3299:
3297:
3294:
3292:
3289:
3287:
3284:
3282:
3279:
3277:
3274:
3272:
3269:
3267:
3264:
3262:
3259:
3257:
3254:
3252:
3249:
3247:
3244:
3242:
3239:
3237:
3234:
3232:
3229:
3227:
3224:
3222:
3219:
3218:
3216:
3213:
3209:
3203:
3200:
3198:
3195:
3193:
3190:
3188:
3185:
3184:
3182:
3179:
3175:
3171:
3166:
3161:
3157:
3143:
3140:
3138:
3135:
3133:
3130:
3128:
3125:
3124:
3122:
3119:
3115:
3109:
3106:
3104:
3101:
3100:
3098:
3095:
3091:
3085:
3082:
3080:
3077:
3075:
3072:
3070:
3067:
3065:
3062:
3061:
3059:
3056:
3052:
3046:
3043:
3041:
3038:
3036:
3033:
3031:
3028:
3027:
3025:
3022:
3018:
3012:
3009:
3007:
3004:
3002:
2999:
2997:
2994:
2992:
2989:
2987:
2984:
2982:
2979:
2977:
2974:
2972:
2969:
2967:
2964:
2962:
2959:
2957:
2954:
2952:
2949:
2947:
2944:
2942:
2939:
2937:
2934:
2932:
2929:
2927:
2924:
2922:
2919:
2917:
2914:
2912:
2909:
2907:
2904:
2902:
2899:
2897:
2894:
2892:
2889:
2887:
2884:
2882:
2879:
2877:
2874:
2872:
2869:
2867:
2864:
2862:
2859:
2857:
2854:
2852:
2849:
2847:
2844:
2842:
2839:
2837:
2834:
2832:
2829:
2827:
2824:
2822:
2819:
2817:
2814:
2812:
2809:
2807:
2804:
2802:
2799:
2797:
2794:
2792:
2789:
2787:
2784:
2782:
2779:
2777:
2774:
2772:
2769:
2767:
2764:
2762:
2759:
2757:
2754:
2752:
2749:
2747:
2744:
2742:
2739:
2737:
2734:
2733:
2731:
2728:
2724:
2718:
2715:
2713:
2710:
2708:
2705:
2704:
2702:
2699:
2695:
2689:
2686:
2684:
2681:
2680:
2678:
2675:
2671:
2665:
2662:
2661:
2659:
2656:
2652:
2646:
2643:
2641:
2638:
2636:
2633:
2631:
2628:
2626:
2623:
2621:
2618:
2616:
2613:
2611:
2608:
2606:
2603:
2601:
2598:
2596:
2593:
2591:
2588:
2586:
2583:
2582:
2580:
2577:
2573:
2567:
2564:
2562:
2559:
2558:
2556:
2553:
2549:
2543:
2540:
2538:
2535:
2533:
2530:
2528:
2525:
2523:
2520:
2519:
2517:
2514:
2510:
2504:
2501:
2499:
2496:
2494:
2491:
2489:
2486:
2484:
2481:
2479:
2476:
2475:
2473:
2470:
2466:
2459:
2458:
2456:
2454:(EC 2.7.11.9)
2453:
2449:
2443:
2440:
2438:
2435:
2434:
2432:
2430:(EC 2.7.11.8)
2429:
2425:
2417:
2414:
2412:
2409:
2407:
2404:
2403:
2402:
2401:Aurora kinase
2399:
2398:
2396:
2394:(EC 2.7.11.7)
2393:
2389:
2383:
2380:
2379:
2377:
2375:(EC 2.7.11.6)
2374:
2370:
2364:
2361:
2359:
2356:
2354:
2351:
2349:
2346:
2345:
2343:
2341:(EC 2.7.11.5)
2340:
2336:
2330:
2327:
2325:
2322:
2320:
2317:
2316:
2314:
2312:(EC 2.7.11.4)
2311:
2307:
2299:
2296:
2294:
2291:
2289:
2286:
2285:
2283:
2279:
2276:
2274:
2271:
2270:
2268:
2264:
2261:
2259:
2256:
2255:
2253:
2250:
2249:
2247:
2245:(EC 2.7.11.3)
2244:
2240:
2234:
2231:
2229:
2226:
2224:
2221:
2219:
2216:
2215:
2213:
2211:(EC 2.7.11.2)
2210:
2206:
2198:
2195:
2194:
2193:
2190:
2186:
2183:
2181:
2178:
2176:
2173:
2171:
2168:
2167:
2166:
2165:EIF-2 kinases
2163:
2161:
2158:
2156:
2153:
2149:
2146:
2144:
2141:
2139:
2136:
2135:
2134:
2131:
2129:
2126:
2124:
2121:
2119:
2116:
2114:
2111:
2109:
2106:
2104:
2101:
2099:
2096:
2094:
2091:
2089:
2086:
2084:
2081:
2079:
2076:
2075:
2073:
2071:(EC 2.7.11.1)
2070:
2066:
2062:
2057:
2052:
2048:
2043:
2039:
2035:
2028:
2023:
2021:
2016:
2014:
2009:
2008:
2005:
1999:
1995:
1992:
1989:
1988:
1984:
1977:
1973:
1968:
1963:
1960:(3): 1621–7.
1959:
1955:
1951:
1946:
1942:
1938:
1933:
1928:
1924:
1920:
1916:
1911:
1907:
1903:
1898:
1893:
1889:
1885:
1882:(9): 1711–8.
1881:
1877:
1873:
1868:
1864:
1860:
1855:
1850:
1846:
1842:
1838:
1834:
1830:
1825:
1821:
1817:
1813:
1809:
1804:
1799:
1795:
1791:
1784:
1779:
1775:
1771:
1766:
1761:
1757:
1753:
1749:
1744:
1743:
1738:
1730:
1726:
1721:
1716:
1711:
1706:
1702:
1698:
1695:(1): e52011.
1694:
1690:
1686:
1679:
1676:
1671:
1667:
1662:
1657:
1653:
1649:
1645:
1641:
1637:
1630:
1627:
1622:
1618:
1613:
1608:
1604:
1600:
1596:
1592:
1588:
1581:
1578:
1573:
1569:
1564:
1559:
1555:
1551:
1548:(4): 575–86.
1547:
1543:
1539:
1532:
1529:
1524:
1520:
1515:
1510:
1505:
1500:
1496:
1492:
1488:
1481:
1478:
1473:
1469:
1464:
1459:
1454:
1449:
1445:
1441:
1437:
1430:
1428:
1426:
1422:
1417:
1411:
1409:
1407:
1403:
1398:
1394:
1389:
1384:
1380:
1376:
1372:
1365:
1363:
1359:
1354:
1350:
1344:
1341:
1336:
1332:
1326:
1323:
1319:
1315:
1310:
1308:
1306:
1302:
1298:
1294:
1289:
1287:
1285:
1281:
1275:
1273:
1271:
1262:
1260:
1258:
1254:
1246:
1244:
1242:
1241:
1236:
1232:
1228:
1224:
1219:
1215:
1210:
1208:
1204:
1199:
1197:
1193:
1185:
1183:
1181:
1180:
1175:
1174:
1169:
1168:
1163:
1162:
1157:
1156:
1155:R. norvegicus
1151:
1150:
1145:
1144:
1139:
1138:
1132:
1130:
1127:
1123:
1119:
1107:
1102:
1098:
1094:
1091:
1087:
1080:
1078:
1075:
1071:
1067:
1063:
1060:
1056:
1052:
1045:
1043:
1037:
1033:
1030:
1024:
1022:
1016:
1012:
1009:
1005:
998:
996:
990:
986:
983:
977:
975:
969:
965:
962:
960:RefSeq (mRNA)
958:
951:
950:
945:
941:
938:
932:
931:
926:
922:
919:
917:
913:
906:
905:
900:
896:
893:
887:
886:
882:
877:
873:
870:
868:
864:
857:
856:
851:
847:
844:
838:
837:
832:
828:
825:
823:
819:
816:
813:
811:
808:
804:
801:
797:
793:
786:
782:
777:
771:
768:
766:
763:
761:
758:
756:
753:
751:
748:
746:
743:
741:
738:
736:
733:
731:
728:
726:
723:
721:
718:
716:
713:
711:
708:
706:
703:
701:
698:
696:
693:
691:
688:
686:
683:
681:
678:
676:
673:
672:
670:
667:
666:
660:
657:
655:
652:
650:
649:cell junction
647:
645:
642:
640:
637:
635:
632:
630:
627:
625:
622:
620:
617:
615:
612:
610:
607:
605:
602:
600:
599:autophagosome
597:
595:
592:
590:
587:
585:
582:
580:
577:
576:
574:
571:
570:
564:
561:
559:
556:
554:
551:
549:
546:
544:
541:
539:
536:
534:
531:
529:
526:
524:
521:
519:
516:
515:
513:
510:
509:
506:
505:Gene ontology
502:
498:
486:
481:
478:
476:
472:
464:
459:
448:
444:
440:
436:
432:
428:
424:
420:
416:
412:
411:
408:
404:
399:
396:
386:
382:
378:
374:
370:
366:
362:
358:
354:
350:
349:
346:
342:
337:
334:
333:
330:
328:
324:
322:
321:
317:
316:
313:
311:
307:
303:
299:
295:
287:
282:
278:
274:
269:
263:15|15 D3
259:
255:
248:
241:
235:
228:
220:
216:
212:
207:
203:
198:
194:
186:
181:
177:
173:
168:
158:
154:
147:
140:
134:
127:
123:
117:
113:
109:
104:
100:
95:
91:
87:
83:
79:
75:
71:
67:
63:
59:
51:
46:
39:
34:
29:
25:
20:
4133:Translocases
4130:
4117:
4104:
4091:
4078:
4068:Transferases
4065:
4052:
3909:Binding site
3423:
3340:P70S6 kinase
1957:
1953:
1922:
1918:
1879:
1875:
1836:
1832:
1793:
1789:
1755:
1751:
1692:
1688:
1678:
1643:
1639:
1629:
1594:
1590:
1580:
1545:
1541:
1531:
1494:
1490:
1480:
1443:
1439:
1378:
1374:
1352:
1343:
1334:
1325:
1270:ciliopathies
1266:
1250:
1247:Interactions
1238:
1235:ciliogenesis
1211:
1200:
1189:
1177:
1171:
1165:
1159:
1153:
1147:
1141:
1135:
1133:
1125:
1117:
1116:
1039:
1018:
992:
971:
947:
928:
902:
879:
853:
834:
814:
809:
700:MAPK cascade
639:cytoskeleton
425:right kidney
413:spermatocyte
363:right testis
325:
318:
183:143,722,458
170:143,716,340
53:External IDs
3904:Active site
3791:(EC 2.7.12)
3178:Polo kinase
3118:Polo kinase
1149:M. musculus
548:ATP binding
359:left testis
284:75,871,003
271:75,865,618
31:Identifiers
4176:Categories
4107:Isomerases
4081:Hydrolases
3948:Regulation
2469:IκB kinase
2044:2.7.11-12)
1446:: e01828.
1320:, May 2017
1299:, May 2017
1276:References
1214:carcinomas
1173:C. elegans
379:right lung
329:(ortholog)
66:HomoloGene
4187:EC 2.7.11
3986:EC number
2595:PKC alpha
1640:Autophagy
1240:X. laevis
1179:X. laevis
1143:B. taurus
1042:NP_808590
1021:NP_620590
995:NM_177922
974:NM_139021
800:Orthologs
604:centriole
594:cytoplasm
429:spermatid
74:GeneCards
4010:Kinetics
3934:Cofactor
3897:Activity
2951:KIAA0999
2846:MAPKAPK5
2841:MAPKAPK3
2836:MAPKAPK2
1994:Archived
1941:12239168
1906:15342556
1863:16336213
1820:45690153
1812:16484222
1774:16624805
1729:23326322
1689:PLOS ONE
1670:22948227
1621:25823377
1597:: 6666.
1572:20733054
1523:21190936
1472:24618899
1397:11875070
1316:–
1295:–
1186:Function
1161:D. rerio
1090:Wikidata
779:Sources:
4166:Biology
4120:Ligases
3890:Enzymes
3610:MAP3K14
3588:MAP3K11
3583:MAP3K10
3573:MAP3K13
3568:MAP3K12
3370:RPS6KC1
3365:RPS6KA1
3360:RPS6KA3
3355:RPS6KA2
3350:RPS6KB2
3335:RPS6KA4
3330:RPS6KA5
2981:Kalirin
2946:SNF1LK2
2185:EIF2AK4
2180:EIF2AK3
2034:Kinases
1976:9880541
1854:1386035
1720:3543423
1697:Bibcode
1661:3541284
1599:Bibcode
1563:2928013
1514:3048734
1463:3945522
1318:Ensembl
1297:Ensembl
1253:GABARAP
916:UniProt
867:Ensembl
806:Species
785:QuickGO
634:spindle
614:axoneme
589:nucleus
304:pattern
62:2652894
38:Aliases
4152:Portal
4094:Lyases
3840:MAP2K7
3835:MAP2K6
3830:MAP2K5
3825:MAP2K4
3820:MAP2K3
3815:MAP2K2
3810:MAP2K1
3761:ACVRL1
3756:ACVR2B
3751:ACVR2A
3746:ACVR1C
3741:ACVR1B
3724:BMPR1B
3719:BMPR1A
3593:MAP3K7
3578:MAP3K9
3529:MAP3K8
3524:MAP3K7
3519:MAP3K6
3514:MAP3K5
3509:MAP3K4
3504:MAP3K3
3499:MAP3K2
3494:MAP3K1
3468:MAPK14
3463:MAPK13
3458:MAPK11
3446:MAPK10
3424:MAPK15
3419:MAPK12
3311:CDC2L1
3286:CDC2L5
2961:SNF1LK
2786:CAMK2G
2781:CAMK2D
2776:CAMK2B
2771:CAMK2A
2761:CAMK1G
2756:CAMK1D
2751:CAMK1B
2746:CAMK1A
2600:PRKCB1
2537:PRKACA
2532:PRKACB
2527:PRKACG
2503:IKBKAP
2329:BCKDHB
2324:BCKDHA
2298:PRKAG3
2293:PRKAG2
2288:PRKAG1
2278:PRKAB2
2273:PRKAB1
2263:PRKAA2
2258:PRKAA1
2103:STK38L
1974:
1939:
1904:
1897:515316
1894:
1861:
1851:
1818:
1810:
1772:
1727:
1717:
1668:
1658:
1619:
1570:
1560:
1521:
1511:
1470:
1460:
1395:
1176:, and
1126:MAPK15
1122:enzyme
1076:search
1074:PubMed
949:Q80Y86
930:Q8TD08
855:332110
836:225689
822:Entrez
475:BioGPS
449:embryo
445:embryo
162:8q24.3
78:MAPK15
45:MAPK15
22:MAPK15
4046:Types
3802:MAP2K
3736:ACVR1
3729:BMPR2
3714:BMPR1
3639:GSK-3
3480:MAP3K
3441:MAPK9
3436:MAPK8
3414:MAPK7
3409:MAPK6
3404:MAPK4
3399:MAPK3
3394:MAPK1
3306:PFTK1
3301:PCTK3
3296:PCTK2
3291:PCTK1
3281:CDK12
3276:CDK10
3251:CDKL5
3231:CDKL2
3108:STK19
3103:EEF2K
3084:PHKG2
3079:PHKG1
3069:PHKA2
3064:PHKA1
3045:MYLK4
3040:MYLK3
3035:MYLK2
3011:DCLK1
3006:Titin
2996:TRIB3
2991:TRIB2
2986:TRIB1
2976:TSSK2
2956:STK40
2941:PSKH1
2936:PRKD3
2931:PRKD2
2911:PHKG2
2906:PHKG1
2896:OBSCN
2891:NUAK2
2886:NUAK1
2881:MKNK2
2876:MKNK1
2866:MARK4
2861:MARK3
2856:MARK2
2851:MARK1
2831:STK11
2826:DAPK3
2821:DAPK2
2816:DAPK1
2811:CHEK2
2806:CHEK1
2791:CAMK4
2766:CAMK2
2741:CAMK1
2736:BRSK2
2630:PRKCQ
2625:PRKCI
2620:PRKCG
2615:PRKCH
2610:PRKCE
2605:PRKCD
2566:PRKG1
2498:IKBKG
2493:IKBKE
2442:STK10
2437:FASTK
2363:IDH3G
2358:IDH3B
2353:IDH3A
2319:BCKDK
2113:ROCK1
2098:STK38
2093:MAST2
2088:MAST1
2083:LATS2
2078:LATS1
1919:Blood
1816:S2CID
1786:(PDF)
1440:eLife
815:Mouse
810:Human
781:Amigo
327:Mouse
320:Human
267:Start
202:Mouse
166:Start
99:Human
70:16371
4138:list
4131:EC7
4125:list
4118:EC6
4112:list
4105:EC5
4099:list
4092:EC4
4086:list
4079:EC3
4073:list
4066:EC2
4060:list
4053:EC1
3629:TPK1
3605:CDC7
3563:MLKs
3556:KSR2
3551:KSR1
3546:BRAF
3541:ARAF
3536:RAFs
3271:CDK9
3266:CDK8
3261:CDK7
3256:CDK6
3246:CDK5
3241:CDK4
3236:CDK3
3226:CDK2
3221:CDK1
3202:PLK4
3197:PLK3
3192:PLK2
3187:PLK1
3142:PLK4
3137:PLK3
3132:PLK2
3127:PLK1
3074:PHKB
3030:MYLK
3001:TRIO
2971:SPEG
2966:SNRK
2926:PKD1
2921:PIM2
2916:PIM1
2901:PASK
2871:MELK
2801:CASK
2796:MLCK
2717:GRK6
2712:GRK5
2707:GRK4
2645:PKN3
2640:PKN2
2542:PRKY
2488:TBK1
2483:IKK2
2478:CHUK
2382:STK4
2348:IDH2
2233:PDK4
2228:PDK3
2223:PDK2
2218:PDK1
2197:WEE1
2192:Wee1
2160:mTOR
2148:AKT3
2143:AKT2
2138:AKT1
2128:SGK3
2123:SGK2
1972:PMID
1937:PMID
1902:PMID
1859:PMID
1808:PMID
1770:PMID
1725:PMID
1666:PMID
1617:PMID
1568:PMID
1519:PMID
1468:PMID
1393:PMID
1129:gene
310:Bgee
258:Band
219:Chr.
157:Band
116:Chr.
3634:TTK
3598:ZAK
2175:HRI
2170:PKR
2118:SGK
2108:CIT
1962:doi
1958:274
1927:doi
1923:100
1892:PMC
1884:doi
1849:PMC
1841:doi
1837:394
1798:doi
1794:281
1760:doi
1756:281
1715:PMC
1705:doi
1656:PMC
1648:doi
1607:doi
1558:PMC
1550:doi
1546:190
1509:PMC
1499:doi
1495:286
1458:PMC
1448:doi
1383:doi
1379:277
1272:).
1237:in
1203:SRC
1192:MAP
483:n/a
421:rib
280:End
179:End
82:OMA
58:MGI
4178::
2284:γ
2269:β
2254:α
2042:EC
2036::
1970:.
1956:.
1952:.
1935:.
1921:.
1917:.
1900:.
1890:.
1880:14
1878:.
1874:.
1857:.
1847:.
1835:.
1831:.
1814:.
1806:.
1792:.
1788:.
1768:.
1754:.
1750:.
1723:.
1713:.
1703:.
1691:.
1687:.
1664:.
1654:.
1642:.
1638:.
1615:.
1605:.
1593:.
1589:.
1566:.
1556:.
1544:.
1540:.
1517:.
1507:.
1493:.
1489:.
1466:.
1456:.
1442:.
1438:.
1424:^
1405:^
1391:.
1377:.
1373:.
1361:^
1351:.
1333:.
1304:^
1283:^
1182:.
1170:,
1164:,
1158:,
1152:,
1146:,
1140:,
1131:.
783:/
286:bp
273:bp
185:bp
172:bp
80:;
76::
72:;
68::
64:;
60::
4154::
4140:)
4136:(
4127:)
4123:(
4114:)
4110:(
4101:)
4097:(
4088:)
4084:(
4075:)
4071:(
4062:)
4058:(
3882:e
3875:t
3868:v
3691:-
3674:-
3657:-
2460:-
2040:(
2026:e
2019:t
2012:v
1978:.
1964::
1943:.
1929::
1908:.
1886::
1865:.
1843::
1822:.
1800::
1776:.
1762::
1731:.
1707::
1699::
1693:8
1672:.
1650::
1644:8
1623:.
1609::
1601::
1595:6
1574:.
1552::
1525:.
1501::
1474:.
1450::
1444:3
1418:.
1399:.
1385::
1355:.
1337:.
204:)
101:)
84::
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
