931:
Hackett AJ, Smith HS, Springer EL, Owens RB, Nelson-Rees WA, Riggs JL, Gardner MB (1977). "Two syngeneic cell lines from human breast tissue: the aneuploid mammary epithelial (Hs578T) and the diploid myoepithelial (Hs578Bst) cell lines".
895:
Borras M, Lacroix M (1997). "Estrogen receptor-negative/progesterone receptor-positive Evsa-T mammary tumor cells: a model for assessing the biological property of this peculiar phenotype of breast cancers".
1147:
Keydar I, Chen L, Karby S, Weiss FR, Delarea J, Radu M, Chaitcik S, Brenner HJ (1979). "Establishment and characterization of a cell line of human breast carcinoma origin".
27:
Scientists study the behaviour of isolated cells grown in the laboratory for insights into how cells function in the body in health and disease. Experiments using
967:
Kao, Jessica; Salari, Keyan; Bocanegra, Melanie; Choi, Yoon-La; Girard, Luc; Gandhi, Jeet; Kwei, Kevin A.; Hernandez-Boussard, Tina; Wang, Pei (2009-07-03).
640:
1034:
Soule HD, Vazguez J, Long A, Albert S, Brennan M (1973). "A human cell line from a pleural effusion derived from a breast carcinoma".
860:
Lasfargues EY, Coutinho WG, Redfield ES (1978). "Isolation of two human tumor epithelial cell lines from solid breast carcinomas".
969:"Molecular Profiling of Breast Cancer Cell Lines Defines Relevant Tumor Models and Provides a Resource for Cancer Gene Discovery"
784:"Establishment and characterization of a receptor-negative, hormone-nonresponsive breast cancer cell line from an Iraqi patient"
1228:
1120:
689:
638:
Lacroix M, Leclercq G (2004). "Relevance of breast cancer cell lines as models for breast tumours: an update".
1182:
Dorssers, LC; van
Agthoven, T (July 1996). "Genetic mechanisms of estrogen-independence in breast cancer".
1223:
64:
31:
are used for developing new diagnostic tests and new treatments for diseases. This is a list of major
980:
617:
For more data on the nature of TP53 mutations in breast cancer cell lines, see
Lacroix et al. (2006).
735:"A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes"
665:
1199:
1164:
1129:
1100:
1051:
1016:
998:
949:
913:
877:
842:
815:
764:
708:
657:
190:
59:
1191:
1156:
1090:
1082:
1043:
1006:
988:
941:
905:
869:
805:
795:
754:
746:
698:
649:
535:
493:
451:
409:
1118:
Engel LW, Young NA (1978). "Human breast carcinoma cells in continuous culture: a review".
122:
653:
984:
1095:
1070:
1011:
968:
810:
783:
759:
734:
1195:
909:
1217:
1160:
669:
368:
233:
198:
130:
36:
782:
Al-Shammari A, Alshami M, Umran M, Almukhtar A, Yaseen N, Raad K, Hussien A (2015).
28:
993:
750:
608:
The original list was mainly based on the work of
Lacroix and Leclercq (2004).
531:
489:
447:
405:
328:
1047:
1002:
945:
1086:
873:
439:
1020:
846:
833:
Lasfargues EY, Ozzello L (1958). "Cultivation of human breast carcinomas".
819:
768:
712:
661:
1203:
1104:
1055:
917:
17:
1168:
1133:
953:
881:
800:
703:
684:
587:
558:
516:
474:
432:
390:
355:
315:
285:
255:
220:
183:
152:
115:
565:
332:
523:
481:
397:
69:
76:
325:
Invasive ductal carcinoma, mucin-producing, signet-ring type
1069:Cailleau R, Young R, OlivΓ© M, Reeves WJ Jr (1974).
1071:"Breast tumor cell lines from pleural effusions"
8:
683:Lacroix M, Toillon RA, Leclercq G (2006).
1094:
1010:
992:
809:
799:
758:
702:
1075:Journal of the National Cancer Institute
1036:Journal of the National Cancer Institute
934:Journal of the National Cancer Institute
862:Journal of the National Cancer Institute
835:Journal of the National Cancer Institute
46:
630:
601:
728:
726:
724:
722:
7:
553:Yes (with estrogen supplementation)
427:Yes (with estrogen supplementation)
788:Breast Cancer: Targets and Therapy
685:"p53 and breast cancer, an update"
654:10.1023/B:BREA.0000014042.54925.cc
25:
1184:Pathology, Research and Practice
1:
1196:10.1016/S0344-0338(96)80096-3
910:10.1016/S0304-3835(97)00285-1
733:Neve RM, et al. (2006).
1161:10.1016/0014-2964(79)90139-7
994:10.1371/journal.pone.0006146
35:that are primarily used in
1245:
1149:European Journal of Cancer
751:10.1016/j.ccr.2006.10.008
570:Invasive ductal carcinoma
528:Invasive ductal carcinoma
486:Invasive ductal carcinoma
402:Invasive ductal carcinoma
365:Invasive ductal carcinoma
295:Invasive ductal carcinoma
265:Invasive ductal carcinoma
230:Invasive ductal carcinoma
195:Invasive ductal carcinoma
127:Invasive ductal carcinoma
95:Invasive ductal carcinoma
690:Endocrine-Related Cancer
33:breast cancer cell lines
641:Breast Cancer Res Treat
1128:(11 Pt 2): 4327β4339.
1048:10.1093/jnci/51.5.1409
946:10.1093/jnci/58.6.1795
65:Progesterone receptors
37:breast cancer research
1087:10.1093/jnci/53.3.661
874:10.1093/jnci/61.4.967
985:2009PLoSO...4.6146K
801:10.2147/BCTT.S74509
704:10.1677/erc.1.01172
81:Tumorigenic in mice
60:Estrogen receptors
43:List of cell lines
593:
592:
16:(Redirected from
1236:
1229:Human cell lines
1208:
1207:
1179:
1173:
1172:
1144:
1138:
1137:
1115:
1109:
1108:
1098:
1066:
1060:
1059:
1042:(5): 1409β1416.
1031:
1025:
1024:
1014:
996:
964:
958:
957:
940:(6): 1795β1806.
928:
922:
921:
892:
886:
885:
857:
851:
850:
841:(6): 1131β1147.
830:
824:
823:
813:
803:
779:
773:
772:
762:
730:
717:
716:
706:
680:
674:
673:
635:
618:
615:
609:
606:
536:pleural effusion
494:pleural effusion
452:pleural effusion
410:pleural effusion
47:
21:
1244:
1243:
1239:
1238:
1237:
1235:
1234:
1233:
1214:
1213:
1212:
1211:
1181:
1180:
1176:
1146:
1145:
1141:
1121:Cancer Research
1117:
1116:
1112:
1068:
1067:
1063:
1033:
1032:
1028:
966:
965:
961:
930:
929:
925:
894:
893:
889:
859:
858:
854:
832:
831:
827:
781:
780:
776:
732:
731:
720:
682:
681:
677:
637:
636:
632:
627:
622:
621:
616:
612:
607:
603:
598:
87:External links
56:Origin of cells
45:
23:
22:
15:
12:
11:
5:
1242:
1240:
1232:
1231:
1226:
1216:
1215:
1210:
1209:
1174:
1155:(5): 659β670.
1139:
1110:
1081:(3): 661β674.
1061:
1026:
959:
923:
898:Cancer Letters
887:
868:(4): 967β978.
852:
825:
794:(7): 223β230.
774:
745:(6): 515β527.
718:
697:(2): 293β325.
675:
648:(3): 249β289.
629:
628:
626:
623:
620:
619:
610:
600:
599:
597:
594:
591:
590:
585:
583:
581:
579:
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568:
562:
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551:
548:
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542:
539:
529:
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519:
514:
512:
509:
506:
503:
500:
497:
487:
484:
478:
477:
472:
470:
467:
464:
461:
458:
455:
445:
444:Adenocarcinoma
442:
436:
435:
430:
428:
425:
424:No (wild-type)
422:
419:
416:
413:
403:
400:
394:
393:
388:
386:
383:
380:
377:
374:
371:
366:
363:
359:
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353:
351:
348:
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283:
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259:
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245:
242:
239:
236:
231:
228:
224:
223:
218:
216:
213:
210:
207:
204:
201:
196:
193:
187:
186:
181:
179:
177:
174:
171:
168:
165:
163:
162:Adenocarcinoma
160:
156:
155:
150:
148:
145:
142:
139:
136:
133:
128:
125:
119:
118:
113:
111:
109:
106:
104:
101:
98:
96:
93:
89:
88:
85:
82:
79:
73:
67:
62:
57:
54:
51:
44:
41:
24:
14:
13:
10:
9:
6:
4:
3:
2:
1241:
1230:
1227:
1225:
1224:Breast cancer
1222:
1221:
1219:
1205:
1201:
1197:
1193:
1190:(7): 743β51.
1189:
1185:
1178:
1175:
1170:
1166:
1162:
1158:
1154:
1150:
1143:
1140:
1135:
1131:
1127:
1123:
1122:
1114:
1111:
1106:
1102:
1097:
1092:
1088:
1084:
1080:
1076:
1072:
1065:
1062:
1057:
1053:
1049:
1045:
1041:
1037:
1030:
1027:
1022:
1018:
1013:
1008:
1004:
1000:
995:
990:
986:
982:
978:
974:
970:
963:
960:
955:
951:
947:
943:
939:
935:
927:
924:
919:
915:
911:
907:
903:
899:
891:
888:
883:
879:
875:
871:
867:
863:
856:
853:
848:
844:
840:
836:
829:
826:
821:
817:
812:
807:
802:
797:
793:
789:
785:
778:
775:
770:
766:
761:
756:
752:
748:
744:
740:
736:
729:
727:
725:
723:
719:
714:
710:
705:
700:
696:
692:
691:
686:
679:
676:
671:
667:
663:
659:
655:
651:
647:
643:
642:
634:
631:
624:
614:
611:
605:
602:
595:
589:
586:
584:
582:
580:
578:
576:
574:
572:
569:
567:
564:
563:
560:
557:
555:
552:
549:
546:
543:
540:
537:
533:
530:
527:
525:
522:
521:
518:
515:
513:
510:
507:
504:
501:
498:
495:
491:
488:
485:
483:
480:
479:
476:
473:
471:
468:
465:
462:
459:
456:
453:
449:
446:
443:
441:
438:
437:
434:
431:
429:
426:
423:
420:
417:
414:
411:
407:
404:
401:
399:
396:
395:
392:
389:
387:
384:
381:
378:
375:
372:
370:
367:
364:
361:
360:
357:
354:
352:
349:
346:
343:
340:
337:
334:
330:
327:
324:
321:
320:
317:
314:
312:
310:
307:
305:
302:
299:
297:
294:
291:
290:
287:
284:
282:
280:
277:
275:
272:
269:
267:
264:
261:
260:
257:
254:
252:
249:
246:
243:
240:
237:
235:
232:
229:
226:
225:
222:
219:
217:
214:
211:
208:
205:
202:
200:
197:
194:
192:
189:
188:
185:
182:
180:
178:
175:
172:
169:
166:
164:
161:
158:
157:
154:
151:
149:
146:
143:
140:
137:
134:
132:
129:
126:
124:
121:
120:
117:
114:
112:
110:
107:
105:
102:
99:
97:
94:
91:
90:
86:
83:
80:
78:
74:
72:amplification
71:
68:
66:
63:
61:
58:
55:
53:Primary tumor
52:
49:
48:
42:
40:
38:
34:
30:
19:
1187:
1183:
1177:
1152:
1148:
1142:
1125:
1119:
1113:
1078:
1074:
1064:
1039:
1035:
1029:
979:(7): e6146.
976:
972:
962:
937:
933:
926:
904:(1): 23β30.
901:
897:
890:
865:
861:
855:
838:
834:
828:
791:
787:
777:
742:
738:
694:
688:
678:
645:
639:
633:
613:
604:
32:
29:cell culture
26:
739:Cancer Cell
588:Cellosaurus
559:Cellosaurus
517:Cellosaurus
475:Cellosaurus
433:Cellosaurus
391:Cellosaurus
356:Cellosaurus
316:Cellosaurus
286:Cellosaurus
256:Cellosaurus
221:Cellosaurus
184:Cellosaurus
153:Cellosaurus
116:Cellosaurus
1218:Categories
625:References
532:Metastasis
490:Metastasis
448:Metastasis
440:MDA-MB-231
406:Metastasis
329:Metastasis
18:MDA-MB 231
1003:1932-6203
670:207628369
84:Reference
50:Cell line
1021:19582160
973:PLOS ONE
847:13611537
820:26300657
769:17157791
713:16728565
662:14758095
75:Mutated
1204:8880875
1105:4412247
1096:7364228
1056:4357757
1012:2702084
981:Bibcode
918:9570382
811:4536763
760:2730521
566:ZR-75-1
369:Primary
333:ascites
234:Primary
199:Primary
131:Primary
1202:
1169:228940
1167:
1134:212193
1132:
1103:
1093:
1054:
1019:
1009:
1001:
954:864756
952:
916:
882:212572
880:
845:
818:
808:
767:
757:
711:
668:
660:
362:Hs578T
322:Evsa-T
292:BT-549
262:BT-483
227:BT-474
92:600MPE
666:S2CID
596:Notes
524:T-47D
482:SkBr3
398:MCF-7
191:BT-20
159:AU565
123:AMJ13
70:ERBB2
1200:PMID
1165:PMID
1130:PMID
1101:PMID
1052:PMID
1017:PMID
999:ISSN
950:PMID
914:PMID
878:PMID
843:PMID
816:PMID
792:2015
765:PMID
709:PMID
658:PMID
77:TP53
1192:doi
1188:192
1157:doi
1091:PMC
1083:doi
1044:doi
1007:PMC
989:doi
942:doi
906:doi
902:120
870:doi
806:PMC
796:doi
755:PMC
747:doi
699:doi
650:doi
550:Yes
544:Yes
541:Yes
508:Yes
505:Yes
469:Yes
466:Yes
418:Yes
415:Yes
382:Yes
347:Yes
341:Yes
250:Yes
247:Yes
244:Yes
241:Yes
238:Yes
215:Yes
212:Yes
138:Yes
135:Yes
1220::
1198:.
1186:.
1163:.
1153:15
1151:.
1126:38
1124:.
1099:.
1089:.
1079:53
1077:.
1073:.
1050:.
1040:51
1038:.
1015:.
1005:.
997:.
987:.
975:.
971:.
948:.
938:58
936:.
912:.
900:.
876:.
866:61
864:.
839:21
837:.
814:.
804:.
790:.
786:.
763:.
753:.
743:10
741:.
737:.
721:^
707:.
695:13
693:.
687:.
664:.
656:.
646:83
644:.
547:No
511:No
502:No
499:No
463:No
460:No
457:No
421:No
385:No
379:No
376:No
373:No
338:No
209:No
206:No
203:No
141:No
39:.
1206:.
1194::
1171:.
1159::
1136:.
1107:.
1085::
1058:.
1046::
1023:.
991::
983::
977:4
956:.
944::
920:.
908::
884:.
872::
849:.
822:.
798::
771:.
749::
715:.
701::
672:.
652::
538:)
534:(
496:)
492:(
454:)
450:(
412:)
408:(
350:?
344:?
335:)
331:(
308:+
303:β
300:β
278:β
273:+
270:+
176:β
173:+
170:β
167:β
147:-
144:-
108:β
103:β
100:+
20:)
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.