242:
219:
116:
141:
507:
500:
493:
248:
147:
1757:
1161:
Rachez C, Lemon BD, Suldan Z, Bromleigh V, Gamble M, Naar AM, Erdjument-Bromage H, Tempst P, Freedman LP (Jun 1999). "Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex".
1278:"The TRAP/Mediator coactivator complex interacts directly with estrogen receptors alpha and beta through the TRAP220 subunit and directly enhances estrogen receptor function in vitro"
255:
154:
750:
731:
77:
1826:
1802:
1143:
1821:
1125:
1220:"Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators"
241:
1723:
973:
218:
1535:"A mammalian homolog of Drosophila melanogaster transcriptional coactivator intersex is a subunit of the mammalian Mediator complex"
1259:
966:
1112:
1091:
1055:
140:
115:
1108:
1735:
1087:
57:
1051:
254:
153:
1795:
247:
146:
1640:"A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology"
1063:
799:
65:
1570:"Coordination of p300-mediated chromatin remodeling and TRAP/mediator function through coactivator PGC-1alpha"
1675:"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)"
1059:
780:
776:
1605:"A mammalian mediator subunit that shares properties with Saccharomyces cerevisiae mediator subunit Cse2"
1788:
129:
1493:
1362:
1290:
1171:
949:
945:
44:
1404:"Identification and characterization of the potential promoter regions of 1031 kinds of human genes"
1218:
Ito M, Yuan CX, Malik S, Gu W, Fondell JD, Yamamura S, Fu ZY, Zhang X, Qin J, Roeder RG (Apr 1999).
1741:
1729:
898:
890:
1447:"A coregulatory role for the TRAP-mediator complex in androgen receptor-mediated gene expression"
1195:
89:
1482:"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences"
924:
894:
869:
506:
499:
1704:
1661:
1626:
1591:
1556:
1521:
1468:
1433:
1390:
1326:
1308:
1241:
1187:
37:
1772:
1351:"Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex"
1694:
1686:
1651:
1616:
1581:
1546:
1511:
1501:
1458:
1423:
1415:
1380:
1370:
1316:
1298:
1231:
1179:
334:
265:
209:
164:
492:
85:
309:
1497:
1366:
1294:
1175:
1699:
1674:
1586:
1569:
1516:
1481:
1428:
1403:
1321:
1277:
1236:
1219:
665:
660:
655:
650:
645:
640:
635:
630:
625:
609:
604:
599:
594:
578:
573:
568:
558:
553:
548:
1815:
1768:
1385:
1350:
1199:
535:
69:
327:
106:
1656:
1639:
93:
1148:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1130:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1276:
Kang, Yun Kyoung; Guermah
Mohamed; Yuan Chao-Xing; Roeder Robert G (Mar 2002).
410:
226:
123:
73:
1312:
1375:
1088:
ENSG00000175221 GRCh38: Ensembl release 89: ENSG00000282092, ENSG00000175221
695:
470:
348:
293:
280:
192:
179:
81:
1708:
1665:
1630:
1621:
1604:
1595:
1560:
1551:
1534:
1525:
1506:
1472:
1463:
1446:
1437:
1330:
1303:
1245:
1191:
1394:
1013:
1008:
997:
844:
825:
1419:
563:
1690:
811:
762:
1029:
981:
717:
1756:
1260:"Entrez Gene: THRAP5 thyroid hormone receptor associated protein 5"
1183:
680:
676:
1764:
1282:
1036:
515:
61:
1480:
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
1638:
Sato S, Tomomori-Sato C, Parmely TJ, et al. (2004).
1603:
Tomomori-Sato C, Sato S, Parmely TJ, et al. (2004).
661:
transcription initiation from RNA polymerase II promoter
641:
intracellular steroid hormone receptor signaling pathway
317:
1776:
1673:
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
1533:
Sato S, Tomomori-Sato C, Banks CA, et al. (2004).
1568:
Wallberg AE, Yamamura S, Malik S, et al. (2004).
1026:
Mediator of RNA polymerase II transcription subunit 16
482:
48:, DRIP92, THRAP5, TRAP95, mediator complex subunit 16
938:
917:
883:
862:
646:
positive regulation of transcription, DNA-templated
445:
dentate gyrus of hippocampal formation granule cell
1104:
1102:
1100:
1083:
1081:
1079:
666:positive regulation of signaling receptor activity
1402:Suzuki Y, Tsunoda T, Sese J, et al. (2001).
264:
163:
631:regulation of transcription by RNA polymerase II
16:Protein-coding gene in the species Homo sapiens
1271:
1269:
1213:
1211:
1209:
1109:GRCm38: Ensembl release 89: ENSMUSG00000013833
1796:
8:
1445:Wang Q, Sharma D, Ren Y, Fondell JD (2003).
1803:
1789:
691:
651:regulation of transcription, DNA-templated
531:
305:
204:
101:
1698:
1655:
1620:
1585:
1550:
1515:
1505:
1462:
1427:
1384:
1374:
1320:
1302:
1235:
1075:
18:
269:
230:
225:
168:
127:
122:
7:
1753:
1751:
1349:Fondell JD, Ge H, Roeder RG (1996).
636:androgen receptor signaling pathway
1775:. You can help Knowledge (XXG) by
935:
914:
880:
859:
835:
816:
790:
767:
741:
722:
656:transcription by RNA polymerase II
569:transcription coactivator activity
554:transcription coregulator activity
487:
405:
343:
322:
14:
1032:that in humans is encoded by the
1755:
559:thyroid hormone receptor binding
505:
498:
491:
253:
246:
240:
217:
152:
145:
139:
114:
1827:Human chromosome 19 gene stubs
1056:Thyroid hormone receptor alpha
516:More reference expression data
471:More reference expression data
1:
1587:10.1016/S1097-2765(03)00391-5
1283:Proc. Natl. Acad. Sci. U.S.A.
1237:10.1016/S1097-2765(00)80463-3
238:
137:
1822:Genes on human chromosome 19
1657:10.1016/j.molcel.2004.05.006
1486:Proc. Natl. Acad. Sci. U.S.A
1355:Proc. Natl. Acad. Sci. U.S.A
1289:(5). United States: 2642–7.
626:transcription, DNA-templated
1728:human gene location in the
579:signaling receptor activity
1843:
1750:
1740:human gene details in the
549:vitamin D receptor binding
359:mucosa of transverse colon
1144:"Mouse PubMed Reference:"
1126:"Human PubMed Reference:"
1064:Cyclin-dependent kinase 8
1012:
1007:
1003:
996:
980:
961:
942:
921:
910:
887:
866:
855:
842:
838:
823:
819:
810:
797:
793:
774:
770:
761:
748:
744:
729:
725:
716:
701:
694:
690:
674:
534:
530:
513:
490:
481:
468:
417:
408:
355:
346:
316:
308:
304:
287:
274:
237:
216:
207:
203:
186:
173:
136:
113:
104:
100:
55:
52:
42:
35:
30:
26:
21:
1050:MED16 has been shown to
974:Chr 10: 79.73 – 79.74 Mb
437:Rostral migratory stream
1376:10.1073/pnas.93.16.8329
1060:Estrogen receptor alpha
429:external carotid artery
425:internal carotid artery
1622:10.1074/jbc.M312523200
1552:10.1074/jbc.C300444200
1507:10.1073/pnas.242603899
1464:10.1074/jbc.M206061200
1304:10.1073/pnas.261715899
967:Chr 19: 0.87 – 0.89 Mb
441:epithelium of stomach
232:Chromosome 10 (mouse)
130:Chromosome 19 (human)
1742:UCSC Genome Browser
1730:UCSC Genome Browser
1498:2002PNAS...9916899M
1420:10.1101/gr.gr-1640r
1367:1996PNAS...93.8329F
1295:2002PNAS...99.2642K
1176:1999Natur.398..824R
421:seminiferous tubule
375:canal of the cervix
367:right lobe of liver
1763:This article on a
1691:10.1101/gr.2596504
800:ENSMUSG00000013833
619:Biological process
588:Cellular component
564:catalytic activity
542:Molecular function
457:extraocular muscle
449:tibiofemoral joint
391:anterior pituitary
363:right uterine tube
1784:
1783:
1492:(26): 16899–903.
1023:
1022:
1019:
1018:
992:
991:
957:
956:
932:
931:
906:
905:
877:
876:
851:
850:
832:
831:
806:
805:
787:
786:
757:
756:
738:
737:
686:
685:
526:
525:
522:
521:
477:
476:
464:
463:
402:
401:
300:
299:
199:
198:
94:MED16 - orthologs
1834:
1805:
1798:
1791:
1759:
1752:
1712:
1702:
1669:
1659:
1634:
1624:
1599:
1589:
1564:
1554:
1529:
1519:
1509:
1476:
1466:
1441:
1431:
1398:
1388:
1378:
1335:
1334:
1324:
1306:
1273:
1264:
1263:
1256:
1250:
1249:
1239:
1215:
1204:
1203:
1158:
1152:
1151:
1140:
1134:
1133:
1122:
1116:
1106:
1095:
1085:
1005:
1004:
976:
969:
952:
936:
927:
915:
911:RefSeq (protein)
901:
881:
872:
860:
836:
817:
791:
768:
742:
723:
692:
605:mediator complex
532:
518:
509:
502:
495:
488:
473:
413:
411:Top expressed in
406:
351:
349:Top expressed in
344:
323:
306:
296:
283:
272:
257:
250:
244:
233:
221:
205:
195:
182:
171:
156:
149:
143:
132:
118:
102:
96:
47:
40:
19:
1842:
1841:
1837:
1836:
1835:
1833:
1832:
1831:
1812:
1811:
1810:
1809:
1748:
1720:
1715:
1685:(10B): 2121–7.
1672:
1637:
1602:
1567:
1545:(50): 49671–4.
1532:
1479:
1457:(45): 42852–8.
1444:
1401:
1361:(16): 8329–33.
1348:
1344:
1342:Further reading
1339:
1338:
1275:
1274:
1267:
1258:
1257:
1253:
1217:
1216:
1207:
1170:(6730): 824–8.
1160:
1159:
1155:
1142:
1141:
1137:
1124:
1123:
1119:
1107:
1098:
1086:
1077:
1072:
1048:
1042:
1014:View/Edit Mouse
1009:View/Edit Human
972:
965:
962:Location (UCSC)
948:
944:
923:
897:
893:
889:
868:
781:ENSG00000175221
779:
777:ENSG00000282092
670:
614:
583:
574:protein binding
514:
504:
503:
497:
496:
469:
460:
455:
451:
447:
443:
439:
435:
431:
427:
423:
409:
398:
395:muscle of thigh
393:
389:
385:
381:
377:
373:
369:
365:
361:
347:
291:
278:
270:
260:
259:
258:
251:
231:
208:Gene location (
190:
177:
169:
159:
158:
157:
150:
128:
105:Gene location (
56:
43:
36:
17:
12:
11:
5:
1840:
1838:
1830:
1829:
1824:
1814:
1813:
1808:
1807:
1800:
1793:
1785:
1782:
1781:
1760:
1746:
1745:
1733:
1719:
1718:External links
1716:
1714:
1713:
1670:
1635:
1615:(7): 5846–51.
1600:
1580:(5): 1137–49.
1565:
1530:
1477:
1442:
1399:
1345:
1343:
1340:
1337:
1336:
1265:
1251:
1205:
1153:
1135:
1117:
1096:
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1016:
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985:
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954:
950:XP_006513551.1
946:XP_006513550.1
940:
939:
933:
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929:
919:
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403:
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388:
384:
380:
376:
372:
371:gastric mucosa
368:
364:
360:
356:
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352:
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339:
331:
320:
314:
313:
310:RNA expression
302:
301:
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268:
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261:
252:
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98:
97:
54:
50:
49:
41:
33:
32:
28:
27:
24:
23:
15:
13:
10:
9:
6:
4:
3:
2:
1839:
1828:
1825:
1823:
1820:
1819:
1817:
1806:
1801:
1799:
1794:
1792:
1787:
1786:
1780:
1778:
1774:
1770:
1769:chromosome 19
1766:
1761:
1758:
1754:
1749:
1743:
1739:
1738:
1734:
1731:
1727:
1726:
1722:
1721:
1717:
1710:
1706:
1701:
1696:
1692:
1688:
1684:
1680:
1676:
1671:
1667:
1663:
1658:
1653:
1650:(5): 685–91.
1649:
1645:
1641:
1636:
1632:
1628:
1623:
1618:
1614:
1610:
1609:J. Biol. Chem
1606:
1601:
1597:
1593:
1588:
1583:
1579:
1575:
1571:
1566:
1562:
1558:
1553:
1548:
1544:
1540:
1539:J. Biol. Chem
1536:
1531:
1527:
1523:
1518:
1513:
1508:
1503:
1499:
1495:
1491:
1487:
1483:
1478:
1474:
1470:
1465:
1460:
1456:
1452:
1451:J. Biol. Chem
1448:
1443:
1439:
1435:
1430:
1425:
1421:
1417:
1414:(5): 677–84.
1413:
1409:
1405:
1400:
1396:
1392:
1387:
1382:
1377:
1372:
1368:
1364:
1360:
1356:
1352:
1347:
1346:
1341:
1332:
1328:
1323:
1318:
1314:
1310:
1305:
1300:
1296:
1292:
1288:
1285:
1284:
1279:
1272:
1270:
1266:
1261:
1255:
1252:
1247:
1243:
1238:
1233:
1230:(3): 361–70.
1229:
1225:
1221:
1214:
1212:
1210:
1206:
1201:
1197:
1193:
1189:
1185:
1184:10.1038/19783
1181:
1177:
1173:
1169:
1165:
1157:
1154:
1149:
1145:
1139:
1136:
1131:
1127:
1121:
1118:
1114:
1110:
1105:
1103:
1101:
1097:
1093:
1089:
1084:
1082:
1080:
1076:
1069:
1067:
1065:
1061:
1057:
1053:
1045:
1043:
1040:
1038:
1035:
1031:
1027:
1015:
1010:
1006:
1002:
999:
995:
988:
986:
983:
979:
975:
971:
968:
964:
960:
953:
951:
947:
941:
937:
934:
928:
926:
920:
916:
913:
909:
902:
900:
896:
892:
886:
882:
879:
873:
871:
865:
861:
858:
856:RefSeq (mRNA)
854:
847:
846:
841:
837:
834:
828:
827:
822:
818:
815:
813:
809:
802:
801:
796:
792:
789:
783:
782:
778:
773:
769:
766:
764:
760:
753:
752:
747:
743:
740:
734:
733:
728:
724:
721:
719:
715:
712:
709:
707:
704:
700:
697:
693:
689:
682:
678:
673:
667:
664:
662:
659:
657:
654:
652:
649:
647:
644:
642:
639:
637:
634:
632:
629:
627:
624:
623:
621:
618:
617:
611:
608:
606:
603:
601:
598:
596:
593:
592:
590:
587:
586:
580:
577:
575:
572:
570:
567:
565:
562:
560:
557:
555:
552:
550:
547:
546:
544:
541:
540:
537:
536:Gene ontology
533:
529:
517:
512:
508:
501:
494:
489:
486:
484:
480:
472:
467:
456:
452:
448:
444:
440:
436:
432:
428:
424:
420:
419:
416:
412:
407:
404:
394:
390:
386:
382:
379:apex of heart
378:
374:
370:
366:
362:
358:
357:
354:
350:
345:
342:
341:
338:
336:
332:
330:
329:
325:
324:
321:
319:
315:
311:
307:
303:
295:
290:
286:
282:
277:
271:10|10 C1
267:
263:
256:
249:
243:
236:
228:
224:
220:
215:
211:
206:
202:
194:
189:
185:
181:
176:
166:
162:
155:
148:
142:
135:
131:
125:
121:
117:
112:
108:
103:
99:
95:
91:
87:
83:
79:
75:
71:
67:
63:
59:
51:
46:
39:
34:
29:
25:
20:
1777:expanding it
1762:
1747:
1736:
1724:
1682:
1678:
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891:NM_001163276
888:
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433:spermatocyte
333:
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53:External IDs
595:nucleoplasm
387:granulocyte
292:79,744,757
279:79,730,542
31:Identifiers
1816:Categories
1679:Genome Res
1408:Genome Res
1115:, May 2017
1094:, May 2017
1070:References
337:(ortholog)
74:HomoloGene
1767:on human
1644:Mol. Cell
1574:Mol. Cell
1313:0027-8424
1200:204992765
925:NP_005472
895:NM_198107
870:NM_005481
696:Orthologs
82:GeneCards
1709:15489334
1666:15175163
1631:14638676
1596:14636573
1561:14576168
1526:12477932
1473:12218053
1438:11337467
1331:11867769
1246:10198638
1224:Mol Cell
1192:10235266
1111:–
1090:–
1052:interact
998:Wikidata
675:Sources:
610:membrane
191:893,218
178:867,630
1494:Bibcode
1395:8710870
1363:Bibcode
1291:Bibcode
1172:Bibcode
1113:Ensembl
1092:Ensembl
812:UniProt
763:Ensembl
702:Species
681:QuickGO
600:nucleus
312:pattern
170:19p13.3
70:2158394
38:Aliases
1707:
1700:528928
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1164:Nature
1030:enzyme
1028:is an
984:search
982:PubMed
845:Q6PGF3
826:Q9Y2X0
751:216154
718:Entrez
483:BioGPS
62:604062
1771:is a
1737:MED16
1725:MED16
1386:38670
1196:S2CID
1054:with
1034:MED16
732:10025
711:Mouse
706:Human
677:Amigo
453:molar
383:gonad
335:Mouse
328:Human
275:Start
210:Mouse
174:Start
107:Human
86:MED16
78:64602
45:MED16
22:MED16
1773:stub
1765:gene
1705:PMID
1662:PMID
1627:PMID
1592:PMID
1557:PMID
1522:PMID
1469:PMID
1434:PMID
1391:PMID
1327:PMID
1309:ISSN
1242:PMID
1188:PMID
1062:and
1037:gene
318:Bgee
266:Band
227:Chr.
165:Band
124:Chr.
58:OMIM
1695:PMC
1687:doi
1652:doi
1617:doi
1613:279
1582:doi
1547:doi
1543:278
1512:PMC
1502:doi
1459:doi
1455:277
1424:PMC
1416:doi
1381:PMC
1371:doi
1317:PMC
1299:doi
1232:doi
1180:doi
1168:398
288:End
187:End
90:OMA
66:MGI
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