242:
219:
116:
141:
248:
147:
1461:
975:
transcription machinery. This gene has been implicated in the growth of several types of cancer, and inhibition of its expression inhibits the growth and spread of these cancers. Two transcript variants encoding different isoforms have been found for this gene. .
255:
154:
1278:
Zhang H, Jiang H, Wang W, Gong J, Zhang L, Chen Z, Ding Q (2012). "Expression of Med19 in bladder cancer tissues and its role on bladder cancer cell growth".
1379:
Ji-Fu E, Xing JJ, Hao LQ, Fu CG (2012). "Suppression of lung cancer metastasis-related protein 1 (LCMR1) inhibits the growth of colorectal cancer cells".
1346:"Knockdown of MED19 by lentivirus-mediated shRNA in human osteosarcoma cells inhibits cell proliferation by inducing cell cycle arrest in the G0/G1 phase"
1307:
Sun M, Jiang R, Li JD, Luo SL, Gao HW, Jin CY, Shi DL, Wang CG, Wang B, Zhang XY (2011). "MED19 promotes proliferation and tumorigenesis of lung cancer".
1518:
677:
658:
77:
1543:
1110:"MED19 and MED26 are synergistic functional targets of the RE1 silencing transcription factor in epigenetic silencing of neuronal gene expression"
1506:
1065:
1047:
1538:
1153:
Li LH, He J, Hua D, Guo ZJ, Gao Q (2011). "Lentivirus-mediated inhibition of Med19 suppresses growth of breast cancer cells in vitro".
241:
885:
1418:"Suppression of MED19 expression by shRNA induces inhibition of cell proliferation and tumorigenesis in human prostate cancer cells"
892:
218:
1034:
1013:
140:
115:
1030:
1009:
57:
254:
153:
1499:
247:
146:
722:
65:
703:
985:
968:
1492:
129:
44:
843:
796:
1237:"The role of Med19 in the proliferation and tumorigenesis of human hepatocellular carcinoma cells"
1404:
1332:
1178:
89:
868:
847:
817:
792:
1439:
1396:
1367:
1324:
1295:
1266:
1223:
1170:
1141:
972:
37:
1476:
1429:
1388:
1357:
1316:
1287:
1256:
1248:
1213:
1203:
1162:
1131:
1121:
334:
265:
209:
164:
85:
309:
1192:"Overexpression of LCMR1 is significantly associated with clinical stage in human NSCLC"
1261:
1236:
1218:
1191:
1136:
1109:
592:
587:
582:
577:
561:
556:
551:
535:
530:
525:
1532:
1522:
1472:
1362:
1345:
971:, which binds to gene-specific regulatory factors and provides support for the basal
512:
1336:
1182:
69:
1408:
327:
106:
1291:
1434:
1417:
93:
1416:
Cui X, Xu D, Lv C, Qu F, He J, Chen M, Liu Y, Gao Y, Che J, Yao Y, Yu H (2011).
1070:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1052:
National Center for
Biotechnology Information, U.S. National Library of Medicine
410:
1392:
1320:
1166:
226:
123:
73:
1208:
622:
470:
348:
293:
280:
192:
179:
81:
1443:
1400:
1371:
1328:
1299:
1270:
1227:
1190:
Chen L, Liang Z, Tian Q, Li C, Ma X, Zhang Y, Yang Z, Wang P, Li Y (2011).
1174:
1145:
1126:
1083:
1108:
Ding N, Tomomori-Sato C, Sato S, Conaway RC, Conaway JW, Boyer TG (2009).
932:
927:
1252:
916:
767:
748:
952:
734:
689:
900:
644:
1460:
607:
603:
1468:
956:
61:
593:
positive regulation of transcription by RNA polymerase II
317:
1480:
1235:
Zou SW, Ai KX, Wang ZG, Yuan Z, Yan J, Zheng Q (2011).
48:, DT2P1G7, LCMR1, MED19AS, mediator complex subunit 19
967:
The protein encoded by this gene is a subunit of the
482:
1344:Wang T, Hao L, Feng Y, Wang G, Qin D, Gu G (2011).
861:
836:
810:
785:
1026:
1024:
1022:
1005:
1003:
1001:
264:
163:
578:regulation of transcription by RNA polymerase II
16:Protein-coding gene in the species Homo sapiens
1031:GRCm38: Ensembl release 89: ENSMUSG00000027080
1500:
8:
1010:GRCh38: Ensembl release 89: ENSG00000156603
1519:United States National Library of Medicine
1507:
1493:
1084:"Entrez Gene: Mediator complex subunit 19"
618:
588:regulation of transcription, DNA-templated
508:
305:
204:
101:
1433:
1361:
1260:
1217:
1207:
1135:
1125:
1517:This article incorporates text from the
997:
955:that in humans is encoded by the MED19
18:
269:
230:
225:
168:
127:
122:
7:
1457:
1455:
1479:. You can help Knowledge (XXG) by
858:
833:
807:
782:
758:
739:
713:
694:
668:
649:
531:transcription coregulator activity
487:
405:
343:
322:
14:
1459:
1363:10.3727/096504011x12970940207760
253:
246:
240:
217:
152:
145:
139:
114:
1544:Human chromosome 11 gene stubs
471:More reference expression data
1:
1292:10.1016/j.urolonc.2010.10.003
238:
137:
1539:Genes on human chromosome 11
1435:10.5483/bmbrep.2011.44.8.547
583:transcription, DNA-templated
536:transcription factor binding
1155:Cancer Chemother. Pharmacol
945:Mediator complex subunit 19
1560:
1454:
425:medial ganglionic eminence
1393:10.1007/s11033-011-1142-2
1321:10.1007/s11010-011-0835-0
1167:10.1007/s00280-010-1468-9
1066:"Mouse PubMed Reference:"
1048:"Human PubMed Reference:"
931:
926:
922:
915:
899:
880:
865:
840:
829:
814:
789:
778:
765:
761:
746:
742:
733:
720:
716:
701:
697:
688:
675:
671:
656:
652:
643:
628:
621:
617:
601:
511:
507:
495:
490:
481:
468:
417:
408:
355:
346:
316:
308:
304:
287:
274:
237:
216:
207:
203:
186:
173:
136:
113:
104:
100:
55:
52:
42:
35:
30:
26:
21:
1196:J. Exp. Clin. Cancer Res
391:tibialis anterior muscle
1209:10.1186/1756-9966-30-18
893:Chr 2: 84.51 – 84.52 Mb
886:Chr 11: 57.7 – 57.71 Mb
1127:10.1074/jbc.M806514200
371:pancreatic ductal cell
130:Chromosome 11 (human)
1253:10.1038/aps.2010.223
445:olfactory epithelium
232:Chromosome 2 (mouse)
1241:Acta Pharmacol. Sin
1521:, which is in the
1467:This article on a
1309:Mol. Cell. Biochem
723:ENSMUSG00000027080
571:Biological process
545:Cellular component
519:Molecular function
1488:
1487:
973:RNA polymerase II
942:
941:
938:
937:
911:
910:
876:
875:
855:
854:
825:
824:
804:
803:
774:
773:
755:
754:
729:
728:
710:
709:
684:
683:
665:
664:
613:
612:
503:
502:
499:
498:
477:
476:
464:
463:
402:
401:
300:
299:
199:
198:
94:MED19 - orthologs
1551:
1509:
1502:
1495:
1463:
1456:
1447:
1437:
1412:
1375:
1365:
1340:
1303:
1274:
1264:
1231:
1221:
1211:
1186:
1149:
1139:
1129:
1094:
1093:
1091:
1090:
1080:
1074:
1073:
1062:
1056:
1055:
1044:
1038:
1028:
1017:
1007:
969:Mediator complex
924:
923:
895:
888:
871:
859:
850:
834:
830:RefSeq (protein)
820:
808:
799:
783:
759:
740:
714:
695:
669:
650:
619:
557:mediator complex
509:
488:
473:
457:primitive streak
433:ventricular zone
413:
411:Top expressed in
406:
367:secondary oocyte
363:endothelial cell
351:
349:Top expressed in
344:
323:
306:
296:
283:
272:
257:
250:
244:
233:
221:
205:
195:
182:
171:
156:
149:
143:
132:
118:
102:
96:
47:
40:
19:
1559:
1558:
1554:
1553:
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1549:
1548:
1529:
1528:
1514:
1513:
1452:
1450:
1415:
1378:
1343:
1306:
1277:
1234:
1189:
1152:
1107:
1103:
1101:Further reading
1098:
1097:
1088:
1086:
1082:
1081:
1077:
1064:
1063:
1059:
1046:
1045:
1041:
1029:
1020:
1008:
999:
994:
982:
965:
933:View/Edit Mouse
928:View/Edit Human
891:
884:
881:Location (UCSC)
867:
846:
842:
816:
795:
791:
704:ENSG00000156603
597:
566:
540:
526:protein binding
469:
460:
455:
451:
447:
443:
439:
435:
431:
427:
423:
409:
398:
393:
389:
385:
383:mucosa of ileum
381:
377:
373:
369:
365:
361:
347:
291:
278:
270:
260:
259:
258:
251:
231:
208:Gene location (
190:
177:
169:
159:
158:
157:
150:
128:
105:Gene location (
56:
43:
36:
17:
12:
11:
5:
1557:
1555:
1547:
1546:
1541:
1531:
1530:
1512:
1511:
1504:
1497:
1489:
1486:
1485:
1464:
1449:
1448:
1413:
1387:(4): 3675–81.
1381:Mol. Biol. Rep
1376:
1356:(5): 193–201.
1341:
1315:(1–2): 27–33.
1304:
1275:
1232:
1187:
1150:
1120:(5): 2648–56.
1104:
1102:
1099:
1096:
1095:
1075:
1057:
1039:
1018:
996:
995:
993:
990:
989:
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981:
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964:
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936:
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919:
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904:
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541:
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492:
485:
479:
478:
475:
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465:
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461:
459:
458:
454:
450:
446:
442:
441:abdominal wall
438:
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430:
426:
422:
418:
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400:
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392:
388:
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380:
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372:
368:
364:
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353:
352:
340:
339:
331:
320:
314:
313:
310:RNA expression
302:
301:
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289:
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284:
276:
273:
268:
262:
261:
252:
245:
239:
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200:
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196:
188:
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167:
161:
160:
151:
144:
138:
134:
133:
126:
120:
119:
111:
110:
98:
97:
54:
50:
49:
41:
33:
32:
28:
27:
24:
23:
15:
13:
10:
9:
6:
4:
3:
2:
1556:
1545:
1542:
1540:
1537:
1536:
1534:
1527:
1526:
1524:
1523:public domain
1520:
1510:
1505:
1503:
1498:
1496:
1491:
1490:
1484:
1482:
1478:
1474:
1473:chromosome 11
1470:
1465:
1462:
1458:
1453:
1445:
1441:
1436:
1431:
1428:(8): 547–52.
1427:
1423:
1419:
1414:
1410:
1406:
1402:
1398:
1394:
1390:
1386:
1382:
1377:
1373:
1369:
1364:
1359:
1355:
1351:
1347:
1342:
1338:
1334:
1330:
1326:
1322:
1318:
1314:
1310:
1305:
1301:
1297:
1293:
1289:
1285:
1281:
1276:
1272:
1268:
1263:
1258:
1254:
1250:
1247:(3): 354–60.
1246:
1242:
1238:
1233:
1229:
1225:
1220:
1215:
1210:
1205:
1201:
1197:
1193:
1188:
1184:
1180:
1176:
1172:
1168:
1164:
1161:(1): 207–15.
1160:
1156:
1151:
1147:
1143:
1138:
1133:
1128:
1123:
1119:
1115:
1114:J. Biol. Chem
1111:
1106:
1105:
1100:
1085:
1079:
1076:
1071:
1067:
1061:
1058:
1053:
1049:
1043:
1040:
1036:
1032:
1027:
1025:
1023:
1019:
1015:
1011:
1006:
1004:
1002:
998:
991:
987:
984:
983:
979:
977:
974:
970:
962:
960:
958:
954:
950:
946:
934:
929:
925:
921:
918:
914:
907:
905:
902:
898:
894:
890:
887:
883:
879:
872:
870:
864:
860:
857:
851:
849:
845:
839:
835:
832:
828:
821:
819:
813:
809:
806:
800:
798:
794:
788:
784:
781:
779:RefSeq (mRNA)
777:
770:
769:
764:
760:
757:
751:
750:
745:
741:
738:
736:
732:
725:
724:
719:
715:
712:
706:
705:
700:
696:
693:
691:
687:
680:
679:
674:
670:
667:
661:
660:
655:
651:
648:
646:
642:
639:
636:
634:
631:
627:
624:
620:
616:
609:
605:
600:
594:
591:
589:
586:
584:
581:
579:
576:
575:
573:
570:
569:
563:
560:
558:
555:
553:
550:
549:
547:
544:
543:
537:
534:
532:
529:
527:
524:
523:
521:
518:
517:
514:
513:Gene ontology
510:
506:
494:
489:
486:
484:
480:
472:
467:
456:
452:
448:
444:
440:
436:
432:
428:
424:
420:
419:
416:
412:
407:
404:
394:
390:
386:
382:
378:
374:
370:
366:
362:
358:
357:
354:
350:
345:
342:
341:
338:
336:
332:
330:
329:
325:
324:
321:
319:
315:
311:
307:
303:
295:
290:
286:
282:
277:
267:
263:
256:
249:
243:
236:
228:
224:
220:
215:
211:
206:
202:
194:
189:
185:
181:
176:
166:
162:
155:
148:
142:
135:
131:
125:
121:
117:
112:
108:
103:
99:
95:
91:
87:
83:
79:
75:
71:
67:
63:
59:
51:
46:
39:
34:
29:
25:
20:
1516:
1515:
1481:expanding it
1466:
1451:
1425:
1421:
1384:
1380:
1353:
1349:
1312:
1308:
1286:(6): 920–7.
1283:
1279:
1244:
1240:
1199:
1195:
1158:
1154:
1117:
1113:
1087:. Retrieved
1078:
1069:
1060:
1051:
1042:
966:
948:
944:
943:
866:
844:NP_001304007
841:
815:
797:NM_001317078
790:
766:
747:
721:
702:
676:
657:
637:
632:
562:nuclear body
437:cumulus cell
429:spermatocyte
421:pineal gland
333:
326:
53:External IDs
1280:Urol. Oncol
395:skin of arm
387:sural nerve
292:84,518,559
279:84,508,746
191:57,712,221
178:57,703,710
31:Identifiers
1533:Categories
1350:Oncol. Res
1089:2018-02-06
1037:, May 2017
1016:, May 2017
992:References
337:(ortholog)
271:2|2 D
74:HomoloGene
1471:on human
1202:(1): 18.
869:NP_080161
848:NP_703151
818:NM_025885
793:NM_153450
623:Orthologs
82:GeneCards
1444:21871180
1401:21732059
1372:21542455
1337:24675844
1329:21519921
1300:21478038
1271:21372827
1228:21306606
1183:19531562
1175:20890603
1146:19049968
1033:–
1012:–
986:Mediator
980:See also
963:Function
917:Wikidata
602:Sources:
449:epiblast
1422:BMB Rep
1409:1788019
1262:4002777
1219:3045976
1137:2631966
1035:Ensembl
1014:Ensembl
953:protein
951:) is a
735:UniProt
690:Ensembl
629:Species
608:QuickGO
552:nucleus
312:pattern
170:11q12.1
70:1914234
38:Aliases
1442:
1407:
1399:
1370:
1335:
1327:
1298:
1269:
1259:
1226:
1216:
1181:
1173:
1144:
1134:
903:search
901:PubMed
768:Q8C1S0
749:A0JLT2
678:381379
659:219541
645:Entrez
483:BioGPS
379:nipple
359:oocyte
62:612385
1475:is a
1405:S2CID
1333:S2CID
1179:S2CID
949:Med19
638:Mouse
633:Human
604:Amigo
375:gonad
335:Mouse
328:Human
275:Start
210:Mouse
174:Start
107:Human
86:MED19
78:14684
45:MED19
22:MED19
1477:stub
1469:gene
1440:PMID
1397:PMID
1368:PMID
1325:PMID
1296:PMID
1267:PMID
1224:PMID
1171:PMID
1142:PMID
957:gene
453:lens
318:Bgee
266:Band
227:Chr.
165:Band
124:Chr.
58:OMIM
1430:doi
1389:doi
1358:doi
1317:doi
1313:355
1288:doi
1257:PMC
1249:doi
1214:PMC
1204:doi
1163:doi
1132:PMC
1122:doi
1118:284
491:n/a
288:End
187:End
90:OMA
66:MGI
1535::
1438:.
1426:44
1424:.
1420:.
1403:.
1395:.
1385:39
1383:.
1366:.
1354:19
1352:.
1348:.
1331:.
1323:.
1311:.
1294:.
1284:30
1282:.
1265:.
1255:.
1245:32
1243:.
1239:.
1222:.
1212:.
1200:30
1198:.
1194:.
1177:.
1169:.
1159:68
1157:.
1140:.
1130:.
1116:.
1112:.
1068:.
1050:.
1021:^
1000:^
959:.
606:/
294:bp
281:bp
193:bp
180:bp
88:;
84::
80:;
76::
72:;
68::
64:;
60::
1525:.
1508:e
1501:t
1494:v
1483:.
1446:.
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1185:.
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1092:.
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1054:.
947:(
212:)
109:)
92::
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