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for the advancement of research into the treatment of nervous exhaustion and for her original contribution to the fundamental knowledge of the nature of myasthenia gravis, made while carrying out the routine duties of a medical officer at a large metropolitan
332:(low blood potassium levels). She also described the glucose challenge test used in diagnosing hypokalaemic periodic paralysis and the use of intravenous potassium in its treatment. During 1935, her research on myasthenia was incorporated into her
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Letter to Miss Sylvia Bates advocating controlled trial of thymectomy to ascertain its role in the management of myasthenia gravis
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to curare poisoning at that time. The first case of myasthenia gravis successfully treated with physostigmine was published in
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in 1888. The eldest of four children, her father was a solicitor. After school, she trained in medicine at the
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Aitken RS, Allot EN, Gastelden LI, Walker MB (1937). "Observations on a case of familial periodic paralysis".
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196:(17 April 1888 – 13 September 1974) was a Scottish physician who first demonstrated the effectiveness of
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Pearce JM (2005). "Mary
Broadfoot Walker (1888–1974): a historic discovery in myasthenia gravis".
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After her retirement to Croft-an-Righ in 1954, she continued to work part-time at the
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In 1935, Walker was the first to recognise the association between the condition
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In 1934, while working at St Alfege's
Hospital, Walker discovered that the
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Walker MB (1934). "Treatment of myasthenia gravis with physostigmine".
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could temporarily reverse the muscle weakness found in patients with
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Johnston JD (September 2007). "Mary
Broadfoot Walker (1888–1974)".
520:"Dr Mary Walker – A Pioneer in the Treatment of Myasthenia Gravis"
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Walker MB (1935). "Potassium chloride in myasthenia gravis".
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1935 video of the effect of prostigmin on myasthenia gravis
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687:"Some discoveries on myasthenia gravis: the background"
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Alumni of the
University of Edinburgh Medical School
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619:"Contribution to the study of Myasthenia Gravis"
357:She died on 13 September 1974 at the age of 86.
365:In 1962, Walker was the first recipient of the
111:Association of familial periodic paralysis and
354:, a clinical sign found in myasthenia gravis.
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278:Membership of the Royal College of Physicians
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345:Glasgow Royal Maternity and Women's Hospital
311:poisoning, and physostigmine was used as an
157:Glasgow Royal Maternity and Women's Hospital
793:20th-century Scottish women medical doctors
671:. Edinburgh: James Thin. 1937. p. 581.
340:, and for which she received a gold medal.
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736:Encyclopedia of the Neurological Sciences
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653:CS1 maint: multiple names: authors list (
669:Edinburgh University Calendar 1937–1938
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230:Edinburgh College of Medicine for Women
220:Mary Walker was born at Croft-an-Righ,
89:Edinburgh College of Medicine for Women
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106:Treatment of myasthenia gravis with
336:thesis which was submitted via the
200:in the treatment of the condition
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739:. Academic Press. 29 April 2014.
617:Broadfoot, Walker, Mary (1935).
350:Her 1973 article also describes
264:. In 1920 she became a salaried
260:at the 63rd General Hospital,
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803:20th-century women physicians
585:10.1016/S0140-6736(01)09382-5
558:10.1016/S0140-6736(00)94294-6
428:10.1016/S0140-6736(74)92285-5
149:St Francis' Hospital, Dulwich
367:Royal College of Physicians
326:familial periodic paralysis
206:familial periodic paralysis
181:Royal College of Physicians
171:Familial periodic paralysis
37:Dr Mary Walker in the 1920s
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210:low blood potassium levels
490:10.1007/s00415-007-0663-z
422:(7893): 1401–1403. 1974.
266:Assistant Medical Officer
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25:Dr. Mary Broadfoot Walker
685:Walker MB (April 1973).
258:Royal Army Medical Corps
216:Early life and education
183:Jean Hunter Prize (1962)
338:University of Edinburgh
242:University of Edinburgh
85:University of Edinburgh
642:Cite journal requires
352:the Mary Walker Effect
297:subcutaneous injection
290:St Benedict's Hospital
256:, she served with the
152:St Benedict's Hospital
703:10.1136/bmj.2.5857.42
286:St. Francis' Hospital
282:St Leonard's Hospital
280:. She then worked at
194:Mary Broadfoot Walker
145:St Leonard's Hospital
274:St Alfege's Hospital
140:St Alfege's Hospital
552:(5779): 1200–1201.
369:Jean Hunter Prize "
248:Career and research
798:People from Wigton
524:MG -association UK
361:Awards and honours
270:"Poor Law Service"
455:10.1159/000084268
305:myasthenia gravis
202:myasthenia gravis
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167:Myasthenia gravis
95:Years active
72:13 September 1974
16:British physician
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136:Institutions
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113:hypokalaemia
74:(1974-09-13)
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788:1974 deaths
783:1888 births
529:23 November
449:(1): 51–3.
443:Eur. Neurol
292:, Tooting.
252:During the
142:, Greenwich
772:Categories
627:1842/19381
397:References
372:hospital".
318:the Lancet
126:Profession
49:1888-04-17
478:J. Neurol
244:in 1913.
240:from the
154:, Tooting
130:physician
98:1913–1974
81:Education
691:Br Med J
606:: 47–57.
600:Clin Sci
506:29210895
498:18000738
463:15746548
313:antidote
226:Scotland
163:Research
62:Scotland
721:4572033
712:1588990
234:Glasgow
222:Wigtown
58:Wigtown
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573:Lancet
546:Lancet
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416:Lancet
309:curare
238:MB ChB
177:Awards
502:S2CID
377:Notes
262:Malta
741:ISBN
717:PMID
655:link
648:help
531:2008
494:PMID
459:PMID
328:and
208:and
69:Died
43:Born
707:PMC
699:doi
623:hdl
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Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
