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his staff members from becoming infected. The likely explanation in most cases are momentary lapses. Health workers at St. Mary's worked 14 hours shifts for weeks in a row while in layers of protective clothing that were stifling in the equatorial country. All that would be required for infection is for a health worker to lose focus for a moment and, after touching a patient, slip a gloved finger under their mask to scratch an itchy nose or rub an eye. One infected St. Mary's health worker who may have been infected in this way was nurse Simon Ajok. In the early morning of 20 November, Ajok was in the Ebola ward and critical, bleeding from both his nose and gums. Fighting to breathe, Ajok pulled off his oxygen mask and coughed violently, sending a fine spray of blood and mucus against the nearby wall. He then astonished and terrified the night-shift by rising to his feet and staggering into the hallway. The night nurse on duty called Dr. Lukwiya for help. Woken out of bed, Lukwiya put on protective clothing, mask, cap, gown, apron and two pairs of gloves, but not goggles or a face shield to protect the eyes. Explanations for this range from grogginess at being newly awoken or haste to reach a colleague that he had helped train. While it will never be known for certain, the care for Simon Ajok, who died one hour after the physician arrived, is the most likely candidate for
Lukwiya's infection.
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isolation ward. The thought of infections being passed to health workers who did not directly care for Ebola patients panicked many and the nurses mutinied. The day-shift did not go to work; instead 400 health workers, nearly the entire staff of St. Mary's, gathered in the assembly hall of the nursing school. When
Lukwiya rushed down to ask what they wanted, at least one nurse yelled that the hospital should be closed. Lukwiya silenced the nurses, most of whom he had trained himself, by stating that if the hospital closed he would leave Gulu and never return. He then spoke on how he had let himself be abducted by the rebels rather than risk St. Mary's and that they would be responsible for the deaths that would result if the hospital closed. After hours of contentious discussion that extended into the afternoon, Lukwiya switched back to a conciliatory approach, stating that he would remain no matter if everyone left. The meeting ended with him and the nurses singing a song together; he had prevailed.
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Sunday, his breathing had become so laboured that he was put on a respirator. By early Monday evening the oxygen level of his blood was rising and his pulse was near normal. It appeared that he might pull through but later that evening
Lukwiya's lungs began haemorrhaging, a worst-case scenario. Lukwiya died at 1:20 am on Tuesday, 5 December 2000. When Margaret was informed and came to the ward, the body had already been put into a polyethylene bag. When she asked if they could unzip it a little so she could have a last look, she was refused; the body was too infectious to take any risks.
251:. Despite being offered a teaching position at the school, where he earned the best marks in the school's history, he appears to have never considered any other option than returning to St. Mary's. Under Lukwiya's administration the hospital tripled its capacity to 18,000 patients annually, included wounded from both sides of the conflict, and a further 500 out-patients daily. St. Mary's became easily the best hospital in northern Uganda, arguably the best in the country and one of the top hospitals in East Africa. In December 1998, Lukwiya moved his family to the capital city,
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However, despite instituting risk minimisation procedures, including wearing of robes, multiple gloves, surgical masks and goggles, hospital workers continued to fall ill. Twelve more died. At the funeral of an
Italian nun on 7 November, he attempted to rally the morale of his workers: "It is our vocation to save life. It involves risk, but when we serve with love, that is when the risk does not matter so much. When we believe our mission is to save lives, we have got to do our work."
386:. "We said malaria, but we thought Ebola," she later said. His fever grew worse through the day, a Monday, and by Wednesday was vomiting and Dr. Pierre Rollin of the CDC took blood samples for testing. A nurse who was administering an intravenous drip that evening at his home was surprised when he began speaking distinctly, though not to her: "Oh, God, I think I will die in my service. If I die, let me be the last." Then, in a clear voice, he sang "
407:, the cofounder of hospital and a mentor and friend. Teasdale had died in 1996 from AIDS, contracted after she performed surgery on an HIV-positive patient. Among the hundreds of mourners who were warned to stay back until the burial was complete were Lukwiya's children and numerous government officials, including the Minister of Health, who had rushed from Kampala after receiving word that morning.
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health care. Lukwiya was the last health worker at St. Mary's to die from Ebola. Foreign epidemiologists credit
Lukwiya with accelerating the government's public education campaign to stop the spread of the disease with his phone call to Kampala on 8 October. The number of lives possibly saved by this quick action is variously numbered in the hundreds to the thousands.
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seeking a place to sleep that was safe from rebel attacks and abduction. Until the Ebola outbreak, 9000 people sought sanctuary on the hospital grounds nightly to sleep. In a later incident, Lukwiya, his wife
Margaret and five children were lying in bed one evening listening to nearby fighting between the rebels and government forces when a
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On 6 February, the WHO declared that Uganda was Ebola-free, with no new cases in the previous 21 days. 173 people had died. While the survivability rate in previous Ebola outbreaks was as low as 10%, the
Ugandan outbreak had a survivability of nearly 50%, an increase partially attributable to better
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The crisis continued to worsen. By the third week of
October, the number of Ebola patients had increased to almost 60, overwhelming the volunteers in the isolation ward. Lukwiya ordered other nurses to assist the patients and tried to lead by example, working with Ebola patients from 7 am to 8 pm.
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On the morning of 7 October 2000, Lukwiya received a phone call from Opira informing him that a mysterious illness had killed two of the hospital's student nurses, all of whom had begun bleeding or vomiting blood. Opira asked
Lukwiya for help and he arrived that evening, in time to witness the death
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Because of the risks, the burial was carried out at 4pm, as soon as it could be arranged. A team in full protective gear lowered the simple coffin, while one member continually sprayed the coffin and site with Jik bleach as a disinfectant. The location of the grave had been chosen by
Lukwiya while
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cases, in line with the WHO guidelines. The special ward was staffed by three physicians, five nurses and five nursing assistants, all volunteers. When a South African lab confirmed the Ebola outbreak on 15 October, and a WHO delegation arrived in Gulu, they were astonished at the efficiency of the
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to trade for soap. Lukwiya was one of four sons. While his mother started teaching him how to smuggle goods by bicycle, Lukwiya began to prove himself to be an extraordinary student. He came in at the top of his class in grade school, received the top school-leaving marks in the country, going on
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Matters reached a breaking point in late November. While the national epidemic had already peaked, St. Mary's endured a terrible day. In the 24-hour period ending at the dawn of 24 November, seven patients died, three of which were health workers. Two of these were nurses who did not work in the
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that had killed four (4) out of five (5) patients, stated that the sicker a patient, the more infectious they became. Dead bodies themselves were highly contagious. Lukwiya immediately recognised this as a particular problem in Acholiland, where the traditional practice was for the bereaved family
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After finishing his days in the isolation ward, Lukwiya would sit with members of the WHO, CDC and other medical teams that had set up in the hospital compound to offer assistance and take blood samples that allowed them to map the course of the disease. His main question for them was how to stop
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1989, the rebels came to St. Mary's to abduct several Italian nuns. Lukwiya managed to convince the rebels to take him instead and spent a week wandering through the brush in his physician's gown until the rebels released him. He subsequently opened the gates of the hospital compound to people
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described his image: "the fearless field commander at the center of a biological war that threatened everyone in the country". His death shocked the country. Even though the outbreak was in steep decline by the time of Lukwiya's death, it sent shockwaves through the health sector. St. Mary's
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Margaret was finally called on Thursday afternoon and she arrived the next morning. However, Lukwiya's colleagues were strict in the protocols. While she was forced to sit on a stool three feet away from his bed, she was eventually allowed to hold his foot through three layers of glove. On
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On the evening of Sunday, 26 November, two days after he had convinced the nurses to remain on the job, Margaret was startled to hear her husband's voice sound heavily congested. He told her that he had a "terrible flu". The next morning, he and Sister Maria agreed that he had
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of a third nursing student, Daniel Ayella. He had head nurse Sister Maria Di Santo bring him the charts of all unusual deaths in the past two weeks and identified 17 cases with similar symptoms. Lukwiya and Sr. Maria spent most of that night reading reports from the US
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stopped accepting Ebola patients, a number of disillusioned health workers across Gulu District quit, while some suspected Ebola patients refused to go to a hospital, reasoning that if the top medic couldn't be saved there was no point in them seeking treatment.
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named Lukwiya a role model. An annual Dr. Matthew Lukwiya Memorial Lecture began the year after his death. The lectures are sponsored by the World Health Organization and organised by the Uganda National Association of Community and Occupational Health.
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312:. That afternoon, a group of local community leaders came to the hospital reporting that entire families were dying in their villages. He ignored the usual bureaucratic protocols and placed a direct call to Dr. Sam Okware, Uganda's
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But they had implemented the manual – a very specialized recipe. They were giving highly sophisticated care. It was remarkable. There was even a little wooden device for pulling boots off they had made, exactly as the manual
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I had thought people would be unwilling to work. I thought we would be facing a situation where patients were totally neglected and an isolation ward to which people wouldn't want to come because it would just be a
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390:". Rollin came back with the results the next morning; it was Ebola. Lukwiya immediately asked to be put into the isolation ward, stating "Since I am the boss, I should show an example."
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224:, had decided that he would be their successor. He soon came to be known to his colleagues and patients as "Dr. Matthew". Many patients were victims of attacks by the rebel
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to attend university and medical school through a series of scholarships. He took a position as a medical intern at St. Mary's, a Catholic missionary hospital, in 1983.
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shell crashed through the ceiling of their house, but failed to explode. He also played an unpublicised role in advocating for a peaceful solution to the war.
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to take blood samples. By the time the team arrived, Lukwiya had already set up an
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184:(24 November 1957 – 5 December 2000) was a Ugandan physician and the supervisor of
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that caused bleeding. By the end of their review, they suspected
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operation. Dr. Simon Mardel, a member of the WHO team, stated,
296:. The literature on Ebola, largely based on a 1995 outbreak in
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he was in the isolation ward. It is next to the grave of Dr.
361:, where they found corpses abandoned in their hospital beds.
1234:
2023 Marburg virus disease outbreak in Equatorial Guinea
551:, (last updated: 28 May 2002; accessed 4 December 2006)
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Heroes in Health Awards winner for Life time award 2020
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137:"role model", named Memorial Lecture series
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1157:(2019 miniseries based on Preston book)
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192:. He was at the forefront of the 2000
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584:"Kin of Ugandans Recount Ebola Woes"
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318:Uganda Virus Research Institute
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345:The isolation ward of nearby
549:American Medical Association
469:Biosafety level § Gabon
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135:American Medical Association
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709:Operation United Assistance
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388:Onward, Christian Soldiers
111:MSc in Tropical Pediatrics
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694:Reported cases and deaths
565:"The death of Dr Matthew"
286:World Health Organization
208:, grew up in the town of
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464:Body substance isolation
439:Viral haemorrhagic fever
355:Médecins Sans Frontières
310:viral haemorrhagic fever
61:5 December 2000 (age 43)
524:"Dr. Matthew's Passion"
424:In February 2001, the
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226:Lord's Resistance Army
222:Lucille Teasdale-Corti
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853:Taï Forest ebolavirus
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160:Health administration
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1173:Ebola virus disease
679:1976 Zaire outbreak
674:1976 Sudan outbreak
290:infectious diseases
257:Makerere University
204:Lukwiya, an ethnic
194:Ebola virus disease
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398:Burial and legacy
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1166:Miscellaneous
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1050:Salome Karwah
1048:
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1038:
1036:
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1028:
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1026:
1023:
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1008:William Close
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894:Brincidofovir
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824:
820:
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795:
792:
790:
789:2020 Équateur
787:
785:
784:Kivu epidemic
782:
780:
779:2018 Équateur
777:
775:
772:
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766:
764:
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619:
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188:, outside of
187:
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60:
56:
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41:
34:
29:
22:
19:
1470:
1453:
1437:
1420:
1406:Mengla virus
1388:
1367:
1350:
1312:The Hot Zone
1310:
1254:
1198:Marburgvirus
1196:
1153:The Hot Zone
1151:
1141:
1129:(1996 novel)
1123:
1113:
1103:
1091:The Hot Zone
1089:
1059:
1035:Kent Brantly
865:
851:
837:
825:
811:
654:
644:
610:
597:
587:
578:
570:The Observer
568:
527:
480:Epidemiology
459:Sharps waste
423:
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392:
380:
376:
367:
363:
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332:
313:
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278:
239:
219:
203:
181:
180:
166:Institutions
142:
102:
88:
18:
1531:2000 deaths
1526:1957 births
1505:Wikispecies
1455:Thamnovirus
1390:Dianlovirus
1316:(1995 book)
1183:Ebola River
1147:(2016 film)
1137:(2014 meme)
1119:(1996 film)
1109:(1995 film)
947:Triazavirin
904:Favipiravir
646:Filoviridae
269:Pentecostal
263:, took his
245:paediatrics
230:Good Friday
156:paediatrics
77:Citizenship
1520:Categories
1422:Striavirus
1352:Cuevavirus
1134:Ebola-chan
1018:Peter Piot
985:rVSV-ZEBOV
962:cAd3-ZEBOV
929:Lamivudine
729:in Nigeria
719:in Liberia
656:Ebolavirus
486:References
337:describes.
267:wife to a
265:born-again
261:Protestant
1207:Outbreaks
939:TKM-Ebola
749:in the UK
744:in the US
714:in Guinea
699:Responses
666:Outbreaks
288:(WHO) on
200:Biography
1105:Outbreak
980:Vaccines
957:Vaccines
942:(failed)
739:in Spain
689:Timeline
433:See also
334:mortuary
242:tropical
153:Tropical
71:, Uganda
52:, Uganda
1495:Commons
1464:Species
1431:Species
1399:Species
1361:Species
1337:Marburg
1295:FGI-106
1290:FGI-103
1285:BCX4430
1248:Species
1143:93 Days
919:FGI-106
914:FGI-104
909:FGI-103
889:BCX4430
805:Species
724:in Mali
471:(BSL4l)
384:malaria
253:Kampala
1408:(MLAV)
934:mAb114
298:Kikwit
235:mortar
228:. On
210:Kitgum
206:Acholi
149:Fields
131:Awards
80:Uganda
50:Kitgum
973:Drugs
952:ZMapp
924:JK-05
899:DZNep
832:RESTV
444:Ebola
373:Death
326:Ebola
302:Congo
294:Ebola
214:Sudan
1374:LLOV
1267:RAVV
1262:MARV
872:EBOV
859:TAFV
845:SUDV
819:BDBV
774:2017
769:2014
190:Gulu
69:Gulu
58:Died
43:Born
247:in
1522::
586:,
567:,
556:^
547:,
537:^
526:,
494:^
300:,
158:,
67:,
1376:)
1372:(
1099:)
637:e
630:t
623:v
113:)
109:(
99:)
95:(
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