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Meprobamate

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576: 553: 56: 1125: 830:, found meprobamate useful in the alleviation of "mental symptoms": 3% of patients made a complete recovery, 29% were greatly improved, 50% were somewhat better, while 18% realized little change. Self-destructive patients became cooperative and calmer, and experienced a resumption of logical thinking. In 50% of the cases, relaxation brought about more favorable sleep habits. Following the trial, 47: 2102: 879:
In January 1960, Carter Products, Inc. and American Home Products Corporation (which marketed meprobamate as Equanil) were charged with having conspired to monopolize the market in mild tranquilizers. It was revealed that the sale of meprobamate earned $ 40,000,000 for the defendants. Of this amount,
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Meprobamate is licensed for the short-term relief of anxiety, although whether the purported antianxiety effects of meprobamate are separable from its sedative effects is not known. Its effectiveness as a selective agent for the treatment of anxiety has not been proven in humans, and is not used as
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Symptoms of meprobamate overdose include drowsiness, headache, sluggishness, unresponsiveness, or coma; loss of muscle control; severe impairment or cessation of breathing; or shock. Death has been reported with ingestion of as little as 12 g of meprobamate and survival with as much as 40 g. In an
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for which the Committee for Medicinal Products for Human Use concluded that the risks of treatment outweigh the benefits. This review was triggered by concerns from the Norwegian Medical Agency that carisoprodol (converted to meprobamate after administration) was associated with increased risk of
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in New Jersey, Berger and a chemist, Bernard John Ludwig, synthesized a chemically related tranquilizing compound, meprobamate, that overcame these three drawbacks. Wallace Laboratories, a subsidiary of Carter Products, bought the license and named their new product "Miltown" after the borough of
819:, New Jersey. Launched in 1955, it rapidly became the first blockbuster psychotropic drug in American history, becoming popular in Hollywood and gaining fame for its seemingly miraculous effects. It has since been marketed under more than 100 trade names, from Amepromat through Quivet to Zirpon. 838:
were subsequently halted. Meprobamate was found to help in the treatment of alcoholics by 1956. By 1957, over 36 million prescriptions had been filled for meprobamate in the US alone, a billion pills had been manufactured, and it accounted for fully a third of all prescriptions written. Berger,
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for all medicines containing meprobamate, "due to serious side effects seen with the medicine." The Agency's Committee for Medicinal Products for Human Use "concluded that the benefits of meprobamate do not outweigh its risks." In October 2013, Canada also withdrew marketing authorization.
969:, causing sedation and altered perception of pain. Meprobamate has the ability to activate currents even in the absence of GABA. This relatively unique property makes meprobamate exceptionally dangerous when used in combination with other GABA-mediated drugs (including 871:
promoting the drug heavily on his television show, calling himself 'Uncle Miltown'. Miltown soon became ubiquitous in 1950s American life, with 1 in 20 Americans having used it by late 1956, and popular comedians making as many jokes about the drug as they did about
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study found that meprobamate affected driving skills. Though patients reported being able to relax more easily, meprobamate did not completely alleviate their tense feelings. The disclosures came at a special scientific meeting at the
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American Home Products accounted for about two-thirds and Carter about one-third. The U.S. government sought an order mandating that Carter make its meprobamate patent available at no charge to any company desiring to use it.
1082:). For this reason, discontinuation is often achieved through an extended regimen of slowly decreasing doses over a period of weeks or even months. Alternatively, the patient may be switched to a longer-acting 5510: 5530: 802:
in 1946. However, three major drawbacks existed to the use of mephenesin as a tranquilizer: a very short duration of action, greater effect on the spinal cord than on the brain (resulting in a very low
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Production continued throughout the 1960s, but by 1970, meprobamate was listed as a controlled substance after it was discovered to cause physical and psychological dependence.
798:(or myanesin) calmed laboratory rodents without actually sedating them. Berger subsequently referred to this “tranquilizing” effect in a now-historic article, published by the 7520: 941:
Meprobamate's mechanism of action is not completely known. It has been shown in animal studies to have effects at multiple sites in the central nervous system, including the
2100:, Fries FA, Moenkemeyer K, "Verfahren zur Herstellung von 2-Methyl-2-propyl-propandiol-1,3", issued 15 November 1963, assigned to Huels Chemische Werke AG 5496: 5478: 252: 3032: 2870: 1208: 1203:[Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). 899:
disclosed that meprobamate could be addictive at doses not much above recommended. In December 1967, meprobamate was placed under abuse control amendments to the
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Meprobamate, like barbiturates, possesses an analgesic/anesthetic potential. It is also found as a component of the combination analgesic Stopayne capsules .
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addressed an evening session. He predicted the development of many chemicals "capable of changing the quality of human consciousness", in the next few years.
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The European Medicines Agency recommended suspension of marketing authorisations for meprobamate-containing medicines in the European Union in January 2012.
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and acts at the barbiturate binding site (though it is less sedating at effective doses). It is reported to have some anticonvulsant properties against
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Meprobamate, 2-methyl-2-propyl-1,3-propanediol dicarbamate is synthesized by the reaction of 2-methylvaleraldehyde with two molecules of
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was working in a laboratory of a British drug company, looking for a preservative for penicillin, when he noticed that a compound called
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DeLong RE, Phillis JW, Barraco RA (December 1985). "A possible role of endogenous adenosine in the sedative action of meprobamate".
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Meprobamate is available in 200- and 400-mg tablets for oral administration. It is also a component of the combination drug
903:. Records on production and distribution were required to be kept. Limits were placed on prescription duration and refills. 6181: 5519: 4425: 1970: 1204: 1200: 1504: 7513: 5470: 4158: 2593: 974: 472: 6329: 5126: 4076: 6808: 5194: 4305: 2838: 2578: 2145: 1773:"282 MEP (meprobamate-containing medicine) - Market Withdrawal, Effective October 28, 2013 - For Health Professionals" 900: 532: 6601: 4315: 1772: 1050:, requiring physical removal of the undissolved mass of tablets through an endoscope; therefore, administration of 823: 1749:"Questions and answers on the suspension of the marketing uthorisations for oral meprobamate-containing medicines" 7559: 4330: 4325: 4320: 2563: 2177: 910: 835: 277: 31: 4188: 6300: 6234: 5564: 4887: 4883: 4056: 1826:"Assessment of direct gating and allosteric modulatory effects of meprobamate in recombinant GABA(A) receptors" 1108:"In the January 2008 issue of Drug Safety Update, a stop press article announced the recent European review of 421: 6446: 1559:"'BEHAVIOR' DRUGS NOW ENVISIONED; Aldous Huxley Predicts They Will Bring Re-Examining of Ethics and Religion" 1201:"RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" 883:
In April 1965, meprobamate was removed from the list of tranquilizers when experts ruled that the drug was a
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Although it was marketed as being safer, meprobamate has most of the pharmacological effects and dangers of
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Phillis JW, Delong RE (June 1984). "A purinergic component in the central actions of meprobamate".
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Allen MD, Greenblatt DJ, Noel BJ (December 1977). "Meprobamate overdosage: a continuing problem".
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Meprobamate was one of the first drugs to be widely advertised to the general public, with user
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and the subsequent transformation of the resulting 2-methyl-2-propylpropan-1,3-diol into the di
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InChI=1S/C9H18N2O4/c1-3-4-9(2,5-14-7(10)12)6-15-8(11)13/h3-6H2,1-2H3,(H2,10,12)(H2,11,13)
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Ludwig BJ, Piech EC (1951). "Some Anticonvulsant Agents Derived from 1,3-Propanediols".
1266:"The pharmacological properties of α:β-dihydroxy-γ-(2-methylphenoxy)-propane (myanesin)" 575: 552: 376: 7308: 7288: 7053: 6988: 6908: 6888: 6684: 6156: 6085: 5872: 5791: 5425: 5254: 5163: 5030: 5025: 4449: 3337: 3242: 3117: 3082: 3077: 2963: 2928: 2832: 2668: 2510: 2424: 2272: 2246: 1850: 1825: 1411:
Ludwig BJ, Piech E (1951). "Some anticonvulsant agents derived from 1, 3-propanediol".
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The age of anxiety : a history of America's turbulent affair with tranquilizers
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The Age of Anxiety: A History of America's Turbulent Affair with Tranquilizers
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abuse, addiction, intoxication, and psychomotor impairment." February 2008.
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clinical director of Wallace Laboratories, described it as a relaxant of the
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Psychopharmacology for Mental Health Professionals: An Integrative Approach
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should be considered even after 4 or more hours or if levels are rising.
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LiverTox: Clinical and Research Information on Drug-Induced Liver Injury
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is widely believed to be the initial cause of actor and martial artist
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Tooltip α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor
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Goodman And Gilman's The Pharmacological Basis of Therapeutics
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List of psychotropic substances under international control
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therapy for opiate addiction) before attempting tapering.
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The Journal of Pharmacology and Experimental Therapeutics
247: 1472:. National Institute of Standards and Technology (NIST). 236: 223: 2061:"Carisoprodol and meprobamate: risks outweigh benefits" 734: 6776:
Uncompetitive pore blockers (mostly dizocilpine site):
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Tooltip Serotonin antagonist and reuptake inhibitors
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Tooltip Serotonin-norepinephrine reuptake inhibitors
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The Comparative Toxicogenomics Database: Meprobamate
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Toronto: J. Lorimer & Co. p. 27. 893:published the ruling. At the same time, the 37: 2887: 2464: 1364:"The role of serendipity in drug discovery" 7521:Metabotropic glutamate receptor modulators 5511: 5497: 5489: 2878: 2864: 2856: 2185: 2171: 2163: 1943:Brunton L, Lazo J, Parker K (2005-10-28). 1066:drug (US) (S5 in South Africa) under the 574: 551: 460: 255:(Authorized trade only, not prescriptible) 54: 45: 7528:Glutamate metabolism/transport modulators 1949:(11 ed.). McGraw-Hill Professional. 1849: 1387: 1338: 1289: 480: 5940: 2118:Journal of the American Chemical Society 913:withdrew marketing authorization in the 2207: 1438:Tone A (2009). "The Fashionable Pill". 1188: 714: 694: 671:105 to 106 Â°C (221 to 223 Â°F) 547: 440: 355: 124: 7251:Alcohols/volatile anesthetics/related: 2264:Tooltip positive allosteric modulators 2247: 565: 36: 6407:Other positive allosteric modulators: 6187:Tooltip N-Methyl-D-aspartate receptor 1068:Convention on Psychotropic Substances 828:Whitfield, Rankin County, Mississippi 520: 110: 7: 5479:GABA metabolism/transport modulators 2599:Tooltip Monoamine oxidase inhibitors 183: 7148:Ifenprodil (NR2B) site antagonists: 5096:Trichloroethane (methyl chloroform) 2584:Tooltip Tetracyclic antidepressants 1090:(in a manner similar to the use of 500: 391: 5712:Pesampator (BIIB-104, PF-04958242) 4159:11-Methoxy-12-hydroxydehydrokavain 1368:Dialogues in Clinical Neuroscience 1331:10.1111/j.1476-5381.1947.tb00341.x 1282:10.1111/j.1476-5381.1946.tb00046.x 25: 4906:Acetylglycinamide chloral hydrate 2569:Tooltip Tricyclic antidepressants 1824:Kumar M, Dillon GH (March 2016). 1646:. Cengage Learning. p. 129. 1485:"New Hope Arises On Cancer Serum" 1158:2-Methyl-2-propyl-1,3-propanediol 934:, but can exacerbate generalized 1910:European Journal of Pharmacology 1875:European Journal of Pharmacology 1830:European Journal of Pharmacology 1483:Laurence WL (28 December 1955). 1315:"The mode of action of myanesin" 605: 599: 7188:Rislenemdaz (CERC-301, MK-0657) 6135:Negative allosteric modulators: 6023:Positive allosteric modulators: 5846:Negative allosteric modulators: 5599:Positive allosteric modulators: 5326:Menthyl isovalerate (validolum) 1211:from the original on 2023-08-03 800:British Journal of Pharmacology 722:Key:NPPQSCRMBWNHMW-UHFFFAOYSA-N 6424:Tooltip Dehydroepiandrosterone 5732:Tulrampator (S-47445, CX-1632) 5627:Farampator (CX-691, ORG-24448) 4275:Allopregnanolone (brexanolone) 1470:NIST Chemistry WebBook, SRD 69 1140:via successive reactions with 771:drug. It was the best-selling 611: 593: 1: 7514:Receptor/signaling modulators 7363:Unknown/unsorted antagonists: 5927:Unknown/unsorted antagonists: 5520:Ionotropic glutamate receptor 5471:Receptor/signaling modulators 4027:Ampelopsin (dihydromyricetin) 1533:"How Mother Found Her Helper" 810:In May 1950, after moving to 5221:ergoloid (dihydroergotoxine) 4306:anabolic-androgenic steroids 3088:Butabarbital/Secbutabarbital 2893:receptor positive modulators 1922:10.1016/0014-2999(85)90149-9 1887:10.1016/0014-2999(84)90174-2 1842:10.1016/j.ejphar.2016.02.031 975:adenosine reuptake inhibitor 7212:NR2A-selective antagonists: 6744:Polyamine site antagonists: 5969:Acromelic acid (acromelate) 5555:Acromelic acid (acromelate) 3861:Triflunordazepam (Ro5-2904) 1642:Ingersoll E, Rak C (2015). 1380:10.31887/DCNS.2006.8.3/tban 1313:Berger FM (December 1947). 901:Food, Drug and Cosmetic Act 7596: 5652:Hydrochlorothiazide (HCTZ) 4189:5,6,7,8-Tetrahydroyangonin 824:Mississippi State Hospital 583:Chemical and physical data 29: 7580:NMDA receptor antagonists 7505: 6594:Glycine site antagonists: 5464: 4381:Pregnanolone (eltanolone) 2924:Chlorobutanol (cloretone) 2816: 2041:Molloy T (20 July 2018). 2006:10.3109/15563657708988216 1589:. New York: Basic Books. 1531:Dokoupil T (2009-01-22). 1444:. New York: Basic Books. 1039:Side effects and overdose 911:European Medicines Agency 909:On January 19, 2012, the 730: 705: 697:O=C(N)OCC(C)(CCC)COC(N)=O 685: 346: 53: 44: 32:Milltown (disambiguation) 6482:Competitive antagonists: 6390:Polyamine site agonists: 6376:Neboglamine (nebostinel) 5945:Tooltip Kainate receptor 5475:GABA receptor modulators 5385:sulfonmethane (sulfonal) 2158:RxList.com - Meprobamate 1513:. 1956-04-01. p. 28 1270:Br J Pharmacol Chemother 1207:(published 2023-04-04). 977:. Related drugs include 807:), and a weak activity. 7464:Pentamidine isethionate 7208:Traxoprodil (CP-101606) 6447:Epipregnanolone sulfate 2216:Tooltip 5-HT1A receptor 2028:"medicineprices.org.za" 1667:Ranzal E (1960-01-28). 1205:Diário Oficial da UniĂŁo 973:). It is also a potent 949:. Meprobamate binds to 7494:Allosteric modulators: 7429:Ipenoxazone (MLV-6976) 7084:Pethidine (meperidine) 6705:Licostinel (ACEA-1021) 6627:Apimostinel (NRX-1074) 6291:Apimostinel (NRX-1074) 6259:Glycine site agonists: 6091:Licostinel (ACEA-1021) 5802:Licostinel (ACEA-1021) 5687:Mibampator (LY-451395) 5361:Retigabine (ezogabine) 4637:Lirequinil (Ro41-3696) 4204:7,8-Dihydromethysticin 4194:5,6-Dehydromethysticin 3073:Benzylbutylbarbiturate 2256:Tooltip GABAA receptor 2079:US granted 2724720 1129: 1128:Meprobamate synthesis: 1035: 959:neuronal communication 849:University of Michigan 841:central nervous system 767:derivative used as an 7163:CO-101244 (PD-174494) 6879:Delucemine (NPS-1506) 6829:Alazocine (SKF-10047) 2098:CH granted 373026 1585:Tone, Andrea (2009). 1127: 1034: 936:tonic-clonic seizures 7183:Radiprodil (RGH-896) 7158:Buphenine (nylidrin) 6735:Rapastinel (GLYX-13) 6550:Midafotel (d-CPPene) 6457:Pregnenolone sulfate 6381:Rapastinel (GLYX-13) 6172:Pregnenolone sulfate 5913:Pregnenolone sulfate 5416:constituents (e.g., 5200:Deuterated etifoxine 4262:Neuroactive steroids 4232:Apronal (apronalide) 4084:constituents (e.g., 3701:N-Desalkylflurazepam 2491:Gabapentin enacarbil 854:Barbizon Plaza Hotel 763:, among others—is a 753:Wallace Laboratories 232:(Psychoactive drugs) 6414:-Hydroxycholesterol 6225:Homoquinolinic acid 6198:Main site agonists: 5956:Main site agonists: 5550:5-Fluorowillardiine 5547:Main site agonists: 5209:dihydroergocryptine 4521:Pyrazolopyrimidines 4179:5,6-Dihydroyangonin 4164:7,8-Dihydroyangonin 3351:3-Hydroxyphenazepam 3193:Methylphenobarbital 2130:10.1021/ja01156a086 1994:Clinical Toxicology 1425:10.1021/ja01156a086 1232:Let them eat prozac 963:reticular formation 779:due to their wider 219:(Prescription only) 41: 6762:Diethylenetriamine 6441:prasterone sulfate 6216:Homocysteic acid ( 5959:5-Bromowillardiine 5303:4-O-methylhonokiol 4966:Dichloralphenazone 4864:Methylmethaqualone 4441:Nonbenzodiazepines 4154:Desmethoxyyangonin 4149:11-Hydroxyyangonin 4144:11-Methoxyyangonin 4139:10-Methoxyyangonin 3526:Ethyl carfluzepate 3128:Cyclopentobarbital 2843:Never to phase III 1727:The New York Times 1700:The New York Times 1674:The New York Times 1564:The New York Times 1510:The New York Times 1490:The New York Times 1130: 1052:activated charcoal 1036: 890:U.S. Pharmacopoeia 773:minor tranquilizer 7537: 7536: 7388: 7344:Trichloroethylene 7289:Ethanol (alcohol) 6654: 6597:4-Cl-KYN (AV-101) 6365: 6357: 6324: 6316: 6308: 6265: 6250:Tetrazolylglycine 6219: 6157:Ethanol (alcohol) 6146:sodium thiopental 5964:5-Iodowillardiine 5873:Ethanol (alcohol) 5857:sodium thiopental 5486: 5485: 5446:MRK-409 (MK-0343) 5217:dihydroergotamine 5160:potassium bromide 5154:compounds (e.g., 5101:Trichloroethylene 4869:Nitromethaqualone 4788:Pyrazolopyridines 4290:3α-Androstanediol 4184:7,8-Dihydrokavain 3536:Ethyl loflazepate 3313:Thiotetrabarbital 2929:Ethanol (alcohol) 2853: 2852: 2425:Ethanol (alcohol) 2333:Ethyl loflazepate 2124:(12): 5779–5781. 1956:978-0-07-142280-2 1779:. 25 August 2021. 1451:978-0-465-08658-0 1419:(12): 5779–5781. 1062:Meprobamate is a 989:of meprobamate), 957:which interrupts 847:suppressed it. A 834:and all types of 805:therapeutic index 781:therapeutic index 742: 741: 646:Interactive image 533:CompTox Dashboard 275: 263: 250: 239: 227: 214: 148: 96:, and many others 16:(Redirected from 7587: 7560:Muscle relaxants 7386: 7339:Trichloroethanol 6899:Dextromethorphan 6652: 6436: 6425: 6421: 6363: 6355: 6322: 6314: 6306: 6263: 6217: 6188: 6184: 5946: 5942: 5777:Fanapanel (MPQX) 5537: 5533: 5513: 5506: 5499: 5490: 5205:Dihydroergolines 5122:3-Hydroxybutanal 4755:Piperidinediones 4488:Imidazopyridines 4022:6-Methylapigenin 3954:Hydroxyphenamate 3826:SH-053-R-CH3-2′F 3531:Ethyl dirazepate 3411:Chlordiazepoxide 3303:Thiobutabarbital 3015:Trifluoroethanol 3005:Trichloroethanol 2995:-Pentanol (2M2B) 2889: 2880: 2873: 2866: 2857: 2689:Alpha-2 agonists 2679:Alpha-1 blockers 2672: 2600: 2596: 2585: 2581: 2570: 2566: 2555: 2551: 2540: 2536: 2525: 2521: 2479: 2473: 2470: 2298:Chlordiazepoxide 2265: 2261: 2257: 2253: 2217: 2213: 2187: 2180: 2173: 2164: 2134: 2133: 2113: 2107: 2106: 2105: 2101: 2094: 2088: 2087: 2086: 2082: 2075: 2069: 2068: 2067:. February 2008. 2057: 2051: 2050: 2038: 2032: 2031: 2024: 2018: 2017: 1989: 1983: 1982: 1967: 1961: 1960: 1940: 1934: 1933: 1905: 1899: 1898: 1870: 1864: 1863: 1853: 1821: 1815: 1814: 1790: 1781: 1780: 1769: 1763: 1762: 1760: 1759: 1753: 1745: 1739: 1738: 1736: 1735: 1718: 1712: 1711: 1709: 1708: 1691: 1685: 1684: 1682: 1681: 1664: 1658: 1657: 1639: 1633: 1632: 1630: 1629: 1615: 1609: 1608: 1582: 1576: 1575: 1573: 1572: 1555: 1549: 1548: 1546: 1545: 1528: 1522: 1521: 1519: 1518: 1501: 1495: 1494: 1480: 1474: 1473: 1462: 1456: 1455: 1435: 1429: 1428: 1408: 1402: 1401: 1391: 1359: 1353: 1352: 1342: 1310: 1304: 1303: 1293: 1261: 1255: 1254: 1229:Healy D (2003). 1226: 1220: 1219: 1217: 1216: 1193: 1080:delirium tremens 932:absence seizures 843:, whereas other 738: 737: 648: 628: 613: 607: 601: 595: 578: 567: 556: 555: 541: 539: 524: 504: 484: 464: 444: 424: 404: 394: 393: 379: 321: 273: 270: 261: 258: 249: 246: 238: 235: 225: 222: 212: 209: 187: 146: 143: 128: 114: 58: 49: 42: 40: 21: 7595: 7594: 7590: 7589: 7588: 7586: 7585: 7584: 7540: 7539: 7538: 7533: 7501: 7399:Flufenamic acid 7334:Trichloroethane 7109:Rhynchophylline 7029:Methoxphenidine 6994:Levomilnacipran 6894:Dextromethadone 6819:α-Endopsychosin 6423: 6335:Dimethylglycine 6245:Quinolinic acid 6186: 6176: 6014:Quisqualic acid 5944: 5934: 5590:Quisqualic acid 5535: 5525: 5517: 5487: 5482: 5460: 5418:isovaleric acid 5381:Sulfonylalkanes 5279:Hopantenic acid 5263:tolfenamic acid 5251:flufenamic acid 5213:dihydroergosine 5156:lithium bromide 5115:Others/unsorted 5110: 4971:Dichloromethane 4946:Chloral hydrate 4941:Chloral betaine 4878: 4815: 4782: 4749: 4721: 4450:Cyclopyrrolones 4435: 4341:Etiocholanolone 4256: 4213: 4174:5-Hydroxykavain 4124: 4096: 4008: 3890: 3338:Benzodiazepines 3332: 3143:Ethallobarbital 3138:Enallylpropymal 3019: 3000:Tribromoethanol 2987:-Butanol (2M2P) 2933:alcoholic drink 2895: 2892: 2884: 2854: 2849: 2848: 2833:Clinical trials 2812: 2716: 2697:dexmedetomidine 2669:Antiadrenergics 2666: 2665: 2657: 2634: 2598: 2583: 2568: 2553: 2538: 2523: 2511:Antidepressants 2505: 2468: 2461: 2460: 2452: 2434: 2273:Benzodiazepines 2263: 2255: 2251: 2241: 2215: 2211: 2201: 2191: 2142: 2137: 2115: 2114: 2110: 2103: 2096: 2095: 2091: 2084: 2077: 2076: 2072: 2059: 2058: 2054: 2040: 2039: 2035: 2026: 2025: 2021: 1991: 1990: 1986: 1969: 1968: 1964: 1957: 1942: 1941: 1937: 1907: 1906: 1902: 1872: 1871: 1867: 1823: 1822: 1818: 1792: 1791: 1784: 1771: 1770: 1766: 1757: 1755: 1751: 1747: 1746: 1742: 1733: 1731: 1720: 1719: 1715: 1706: 1704: 1693: 1692: 1688: 1679: 1677: 1666: 1665: 1661: 1654: 1641: 1640: 1636: 1627: 1625: 1617: 1616: 1612: 1597: 1584: 1583: 1579: 1570: 1568: 1557: 1556: 1552: 1543: 1541: 1530: 1529: 1525: 1516: 1514: 1503: 1502: 1498: 1482: 1481: 1477: 1464: 1463: 1459: 1452: 1437: 1436: 1432: 1410: 1409: 1405: 1362:Ban TA (2006). 1361: 1360: 1356: 1312: 1311: 1307: 1263: 1262: 1258: 1243: 1228: 1227: 1223: 1214: 1212: 1195: 1194: 1190: 1186: 1154: 1122: 1097:While an acute 1060: 1041: 1023:muscle relaxant 1011: 954: 924: 887:, instead. The 836:shock treatment 812:Carter Products 789: 777:benzodiazepines 733: 731: 726: 723: 718: 713: 712: 701: 698: 693: 692: 661:1.229 g/cm 651: 626: 616: 610: 604: 598: 559: 535: 527: 507: 487: 467: 447: 427: 407: 390: 382: 362: 359: 354: 353: 319: 296:Bioavailability 288:Pharmacokinetic 282: 191: 161: 154: 135: 35: 28: 23: 22: 15: 12: 11: 5: 7593: 7591: 7583: 7582: 7577: 7572: 7567: 7562: 7557: 7552: 7542: 7541: 7535: 7534: 7532: 7531: 7524: 7517: 7506: 7503: 7502: 7500: 7499: 7487: 7486: 7476: 7471: 7466: 7461: 7456: 7451: 7446: 7441: 7436: 7431: 7426: 7421: 7416: 7411: 7406: 7401: 7396: 7391: 7383: 7378: 7373: 7368: 7356: 7351: 7346: 7341: 7336: 7331: 7326: 7321: 7316: 7311: 7309:Methoxyflurane 7306: 7301: 7296: 7291: 7286: 7281: 7276: 7271: 7266: 7261: 7256: 7244: 7239: 7227: 7222: 7217: 7205: 7200: 7195: 7190: 7185: 7180: 7175: 7170: 7165: 7160: 7155: 7150: 7141: 7136: 7131: 7126: 7121: 7116: 7111: 7106: 7101: 7096: 7091: 7086: 7081: 7076: 7071: 7066: 7061: 7056: 7054:Nitromemantine 7051: 7046: 7041: 7036: 7031: 7026: 7021: 7016: 7011: 7006: 7001: 6996: 6991: 6989:Levomethorphan 6986: 6981: 6976: 6971: 6966: 6961: 6956: 6951: 6946: 6941: 6936: 6931: 6926: 6921: 6916: 6911: 6909:Dieticyclidine 6906: 6901: 6896: 6891: 6889:Dextrallorphan 6886: 6881: 6876: 6871: 6866: 6861: 6856: 6851: 6846: 6844:Argiotoxin-636 6841: 6836: 6831: 6826: 6821: 6816: 6811: 6806: 6801: 6796: 6791: 6786: 6781: 6769: 6764: 6759: 6757:Diaminopropane 6754: 6749: 6737: 6732: 6727: 6722: 6717: 6712: 6707: 6702: 6697: 6692: 6687: 6685:Kynurenic acid 6682: 6677: 6672: 6667: 6662: 6657: 6649: 6644: 6639: 6634: 6629: 6624: 6619: 6614: 6609: 6604: 6599: 6587: 6582: 6577: 6572: 6567: 6562: 6557: 6552: 6547: 6542: 6537: 6532: 6527: 6522: 6517: 6512: 6507: 6502: 6497: 6492: 6487: 6475: 6474: 6469: 6464: 6459: 6454: 6449: 6444: 6431: 6416: 6400: 6395: 6383: 6378: 6373: 6368: 6360: 6352: 6347: 6342: 6337: 6332: 6327: 6319: 6311: 6303: 6298: 6293: 6288: 6283: 6278: 6273: 6268: 6252: 6247: 6242: 6237: 6232: 6227: 6222: 6213: 6208: 6203: 6191: 6189: 6178: 6177: 6175: 6174: 6169: 6164: 6159: 6154: 6149: 6128: 6123: 6118: 6113: 6108: 6103: 6098: 6093: 6088: 6086:Kynurenic acid 6083: 6078: 6073: 6068: 6063: 6058: 6049: 6048: 6043: 6038: 6033: 6028: 6016: 6011: 6006: 6001: 5996: 5991: 5986: 5981: 5976: 5971: 5966: 5961: 5949: 5947: 5936: 5935: 5933: 5932: 5920: 5915: 5910: 5905: 5900: 5895: 5890: 5885: 5880: 5875: 5870: 5865: 5860: 5839: 5834: 5829: 5824: 5819: 5814: 5809: 5804: 5799: 5794: 5792:Kynurenic acid 5789: 5784: 5779: 5774: 5769: 5764: 5759: 5754: 5749: 5744: 5735: 5734: 5729: 5724: 5719: 5714: 5709: 5704: 5699: 5694: 5689: 5684: 5679: 5674: 5669: 5664: 5659: 5654: 5649: 5644: 5639: 5634: 5629: 5624: 5619: 5614: 5609: 5604: 5592: 5587: 5582: 5577: 5572: 5567: 5562: 5557: 5552: 5540: 5538: 5527: 5526: 5518: 5516: 5515: 5508: 5501: 5493: 5484: 5483: 5465: 5462: 5461: 5459: 5458: 5453: 5448: 5443: 5434: 5433: 5426:valerenic acid 5411: 5406: 5396: 5378: 5373: 5368: 5363: 5358: 5353: 5348: 5343: 5338: 5333: 5328: 5323: 5318: 5296: 5291: 5286: 5281: 5276: 5271: 5266: 5255:mefenamic acid 5244: 5239: 5234: 5229: 5224: 5202: 5197: 5192: 5187: 5182: 5177: 5172: 5167: 5164:sodium bromide 5149: 5139: 5134: 5129: 5124: 5118: 5116: 5112: 5111: 5109: 5108: 5103: 5098: 5093: 5088: 5083: 5078: 5073: 5068: 5063: 5058: 5053: 5048: 5043: 5038: 5033: 5031:Methoxypropane 5028: 5026:Methoxyflurane 5023: 5018: 5013: 5008: 5003: 4998: 4993: 4988: 4986:Ethyl chloride 4983: 4978: 4973: 4968: 4963: 4958: 4953: 4948: 4943: 4938: 4933: 4928: 4923: 4918: 4913: 4908: 4903: 4898: 4892: 4890: 4880: 4879: 4877: 4876: 4871: 4866: 4861: 4856: 4851: 4846: 4841: 4836: 4831: 4825: 4823: 4821:Quinazolinones 4817: 4816: 4814: 4813: 4808: 4803: 4798: 4792: 4790: 4784: 4783: 4781: 4780: 4775: 4770: 4765: 4759: 4757: 4751: 4750: 4748: 4747: 4742: 4737: 4731: 4729: 4723: 4722: 4720: 4719: 4714: 4709: 4704: 4699: 4694: 4689: 4684: 4679: 4674: 4669: 4664: 4659: 4654: 4649: 4644: 4639: 4634: 4629: 4624: 4619: 4614: 4609: 4604: 4599: 4594: 4589: 4584: 4579: 4574: 4564: 4563: 4558: 4553: 4548: 4543: 4538: 4533: 4528: 4516: 4515: 4510: 4505: 4500: 4495: 4483: 4482: 4477: 4472: 4467: 4462: 4457: 4445: 4443: 4437: 4436: 4434: 4433: 4428: 4423: 4418: 4413: 4408: 4403: 4398: 4393: 4388: 4383: 4378: 4373: 4368: 4363: 4358: 4353: 4348: 4343: 4338: 4333: 4328: 4323: 4318: 4313: 4308: 4302: 4297: 4292: 4287: 4282: 4277: 4272: 4266: 4264: 4258: 4257: 4255: 4254: 4249: 4244: 4239: 4234: 4229: 4223: 4221: 4215: 4214: 4212: 4211: 4206: 4201: 4196: 4191: 4186: 4181: 4176: 4171: 4166: 4161: 4156: 4151: 4146: 4141: 4135: 4133: 4126: 4125: 4123: 4122: 4117: 4112: 4106: 4104: 4098: 4097: 4095: 4094: 4089: 4079: 4074: 4069: 4064: 4059: 4054: 4049: 4044: 4039: 4034: 4029: 4024: 4018: 4016: 4010: 4009: 4007: 4006: 4001: 3996: 3991: 3986: 3981: 3976: 3971: 3966: 3961: 3956: 3951: 3946: 3941: 3936: 3931: 3926: 3921: 3916: 3911: 3906: 3900: 3898: 3892: 3891: 3889: 3888: 3883: 3878: 3873: 3868: 3863: 3858: 3853: 3848: 3843: 3838: 3833: 3828: 3823: 3818: 3813: 3808: 3803: 3798: 3793: 3788: 3783: 3778: 3773: 3768: 3763: 3758: 3753: 3748: 3743: 3738: 3733: 3728: 3723: 3718: 3713: 3708: 3703: 3698: 3693: 3688: 3683: 3678: 3673: 3668: 3663: 3658: 3653: 3648: 3643: 3638: 3633: 3628: 3623: 3618: 3613: 3608: 3603: 3598: 3593: 3588: 3583: 3578: 3573: 3568: 3563: 3558: 3553: 3548: 3543: 3538: 3533: 3528: 3523: 3518: 3513: 3508: 3503: 3498: 3493: 3488: 3483: 3478: 3473: 3468: 3463: 3458: 3453: 3448: 3443: 3438: 3433: 3428: 3423: 3418: 3413: 3408: 3403: 3398: 3393: 3388: 3383: 3378: 3373: 3368: 3363: 3358: 3353: 3348: 3342: 3340: 3334: 3333: 3331: 3330: 3325: 3320: 3315: 3310: 3305: 3300: 3295: 3290: 3285: 3280: 3275: 3270: 3265: 3260: 3255: 3250: 3245: 3243:Propylbarbital 3240: 3235: 3230: 3225: 3220: 3215: 3210: 3205: 3200: 3195: 3190: 3185: 3180: 3175: 3170: 3165: 3160: 3155: 3150: 3145: 3140: 3135: 3130: 3125: 3120: 3118:Crotylbarbital 3115: 3110: 3105: 3100: 3095: 3090: 3085: 3083:Brophebarbital 3080: 3078:Brallobarbital 3075: 3070: 3065: 3060: 3055: 3050: 3045: 3040: 3035: 3029: 3027: 3021: 3020: 3018: 3017: 3012: 3007: 3002: 2997: 2989: 2981: 2976: 2971: 2966: 2964:Methylpentynol 2961: 2956: 2951: 2946: 2941: 2936: 2926: 2921: 2916: 2911: 2905: 2903: 2897: 2896: 2890: 2885: 2883: 2882: 2875: 2868: 2860: 2851: 2850: 2847: 2846: 2845: 2844: 2841: 2830: 2824: 2818: 2817: 2814: 2813: 2811: 2810: 2805: 2800: 2795: 2790: 2785: 2780: 2775: 2770: 2765: 2760: 2755: 2750: 2745: 2740: 2735: 2730: 2724: 2722: 2718: 2717: 2715: 2714: 2704: 2686: 2675: 2673: 2663:Sympatholytics 2659: 2658: 2656: 2655: 2650: 2644: 2642: 2640:Antipsychotics 2636: 2635: 2633: 2632: 2627: 2622: 2617: 2612: 2591: 2576: 2561: 2546: 2531: 2515: 2513: 2507: 2506: 2504: 2503: 2498: 2493: 2488: 2482: 2480: 2466: 2458:Gabapentinoids 2454: 2453: 2451: 2450: 2444: 2442: 2436: 2435: 2433: 2432: 2427: 2422: 2417: 2412: 2402: 2392: 2380: 2375: 2370: 2365: 2360: 2355: 2350: 2345: 2340: 2335: 2330: 2325: 2320: 2315: 2310: 2305: 2300: 2295: 2290: 2285: 2280: 2268: 2266: 2249: 2243: 2242: 2240: 2239: 2234: 2229: 2223: 2221: 2209: 2203: 2202: 2192: 2190: 2189: 2182: 2175: 2167: 2161: 2160: 2155: 2149: 2141: 2140:External links 2138: 2136: 2135: 2108: 2089: 2070: 2052: 2033: 2019: 1984: 1981:on 2015-09-06. 1962: 1955: 1935: 1900: 1881:(3–4): 295–7. 1865: 1816: 1805:(3): 1383–91. 1782: 1764: 1740: 1713: 1686: 1659: 1652: 1634: 1610: 1595: 1577: 1550: 1523: 1496: 1475: 1457: 1450: 1430: 1403: 1354: 1305: 1276:(4): 265–272. 1256: 1242:978-1550287837 1241: 1221: 1199:(2023-03-31). 1187: 1185: 1182: 1181: 1180: 1175: 1170: 1165: 1160: 1153: 1150: 1121: 1118: 1099:cerebral edema 1086:agent such as 1059: 1056: 1040: 1037: 1010: 1007: 952: 923: 920: 915:European Union 896:Medical Letter 788: 785: 740: 739: 728: 727: 725: 724: 721: 719: 716: 708: 707: 706: 703: 702: 700: 699: 696: 688: 687: 686: 683: 682: 679: 673: 672: 669: 663: 662: 659: 653: 652: 650: 649: 641: 639: 631: 630: 624: 618: 617: 614: 608: 602: 596: 591: 585: 584: 580: 579: 569: 561: 560: 558: 557: 544: 542: 529: 528: 526: 525: 517: 515: 509: 508: 506: 505: 497: 495: 489: 488: 486: 485: 477: 475: 469: 468: 466: 465: 457: 455: 449: 448: 446: 445: 437: 435: 429: 428: 426: 425: 417: 415: 409: 408: 406: 405: 397: 395: 384: 383: 381: 380: 372: 370: 364: 363: 361: 360: 357: 349: 348: 347: 344: 343: 339: 338: 333: 327: 326: 323: 314: 313: 308: 302: 301: 298: 292: 291: 284: 283: 281: 280: 268: 256: 244: 233: 220: 206: 204: 198: 197: 193: 192: 190: 189: 176: 174: 168: 167: 164: 162:administration 156: 155: 153: 152: 150: 140: 138: 130: 129: 122: 116: 115: 108: 98: 97: 71: 65: 64: 60: 59: 51: 50: 26: 24: 14: 13: 10: 9: 6: 4: 3: 2: 7592: 7581: 7578: 7576: 7573: 7571: 7568: 7566: 7563: 7561: 7558: 7556: 7553: 7551: 7548: 7547: 7545: 7530: 7529: 7525: 7523: 7522: 7518: 7516: 7515: 7512: 7508: 7507: 7504: 7498: 7495: 7492: 7489: 7488: 7484: 7480: 7479:Transcrocetin 7477: 7475: 7474:Psychotridine 7472: 7470: 7467: 7465: 7462: 7460: 7457: 7455: 7454:Niflumic acid 7452: 7450: 7447: 7445: 7442: 7440: 7437: 7435: 7432: 7430: 7427: 7425: 7422: 7420: 7417: 7415: 7412: 7410: 7407: 7405: 7402: 7400: 7397: 7395: 7392: 7390: 7384: 7382: 7379: 7377: 7374: 7372: 7369: 7367: 7364: 7360: 7357: 7355: 7352: 7350: 7347: 7345: 7342: 7340: 7337: 7335: 7332: 7330: 7327: 7325: 7322: 7320: 7317: 7315: 7314:Nitrous oxide 7312: 7310: 7307: 7305: 7302: 7300: 7297: 7295: 7292: 7290: 7287: 7285: 7282: 7280: 7279:Diethyl ether 7277: 7275: 7272: 7270: 7267: 7265: 7262: 7260: 7257: 7255: 7252: 7248: 7245: 7243: 7240: 7238: 7235: 7231: 7228: 7226: 7223: 7221: 7218: 7216: 7213: 7209: 7206: 7204: 7201: 7199: 7196: 7194: 7191: 7189: 7186: 7184: 7181: 7179: 7176: 7174: 7171: 7169: 7166: 7164: 7161: 7159: 7156: 7154: 7151: 7149: 7145: 7142: 7140: 7137: 7135: 7134:Tenocyclidine 7132: 7130: 7129:Tabernanthine 7127: 7125: 7122: 7120: 7119:Rolicyclidine 7117: 7115: 7112: 7110: 7107: 7105: 7102: 7100: 7097: 7095: 7094:Phencyclidine 7092: 7090: 7089:Phencyclamine 7087: 7085: 7082: 7080: 7077: 7075: 7072: 7070: 7067: 7065: 7062: 7060: 7057: 7055: 7052: 7050: 7047: 7045: 7042: 7040: 7037: 7035: 7032: 7030: 7027: 7025: 7024:Methoxetamine 7022: 7020: 7017: 7015: 7012: 7010: 7007: 7005: 7002: 7000: 6997: 6995: 6992: 6990: 6987: 6985: 6984:Levomethadone 6982: 6980: 6977: 6975: 6972: 6970: 6967: 6965: 6962: 6960: 6957: 6955: 6952: 6950: 6947: 6945: 6944:Fluorolintane 6942: 6940: 6937: 6935: 6932: 6930: 6927: 6925: 6922: 6920: 6917: 6915: 6912: 6910: 6907: 6905: 6902: 6900: 6897: 6895: 6892: 6890: 6887: 6885: 6882: 6880: 6877: 6875: 6872: 6870: 6867: 6865: 6862: 6860: 6857: 6855: 6852: 6850: 6847: 6845: 6842: 6840: 6837: 6835: 6832: 6830: 6827: 6825: 6822: 6820: 6817: 6815: 6812: 6810: 6807: 6805: 6802: 6800: 6797: 6795: 6792: 6790: 6787: 6785: 6782: 6780: 6777: 6773: 6770: 6768: 6765: 6763: 6760: 6758: 6755: 6753: 6750: 6748: 6745: 6741: 6738: 6736: 6733: 6731: 6728: 6726: 6723: 6721: 6718: 6716: 6713: 6711: 6708: 6706: 6703: 6701: 6698: 6696: 6693: 6691: 6688: 6686: 6683: 6681: 6678: 6676: 6673: 6671: 6668: 6666: 6663: 6661: 6658: 6656: 6650: 6648: 6645: 6643: 6640: 6638: 6635: 6633: 6630: 6628: 6625: 6623: 6620: 6618: 6615: 6613: 6610: 6608: 6605: 6603: 6600: 6598: 6595: 6591: 6588: 6586: 6583: 6581: 6578: 6576: 6573: 6571: 6568: 6566: 6563: 6561: 6558: 6556: 6553: 6551: 6548: 6546: 6543: 6541: 6538: 6536: 6533: 6531: 6528: 6526: 6525:Kaitocephalin 6523: 6521: 6518: 6516: 6513: 6511: 6508: 6506: 6503: 6501: 6498: 6496: 6493: 6491: 6488: 6486: 6483: 6480: 6477: 6476: 6473: 6470: 6468: 6465: 6463: 6460: 6458: 6455: 6453: 6450: 6448: 6445: 6442: 6438: 6432: 6429: 6422: 6417: 6415: 6413: 6408: 6404: 6401: 6399: 6396: 6394: 6391: 6387: 6384: 6382: 6379: 6377: 6374: 6372: 6369: 6367: 6361: 6359: 6353: 6351: 6348: 6346: 6343: 6341: 6338: 6336: 6333: 6331: 6328: 6326: 6320: 6318: 6312: 6310: 6304: 6302: 6299: 6297: 6294: 6292: 6289: 6287: 6284: 6282: 6279: 6277: 6274: 6272: 6269: 6267: 6260: 6256: 6253: 6251: 6248: 6246: 6243: 6241: 6238: 6236: 6233: 6231: 6230:Ibotenic acid 6228: 6226: 6223: 6221: 6214: 6212: 6209: 6207: 6204: 6202: 6199: 6196: 6193: 6192: 6190: 6185: 6179: 6173: 6170: 6168: 6165: 6163: 6160: 6158: 6155: 6153: 6150: 6147: 6143: 6142:pentobarbital 6139: 6136: 6132: 6129: 6127: 6124: 6122: 6119: 6117: 6114: 6112: 6109: 6107: 6104: 6102: 6099: 6097: 6094: 6092: 6089: 6087: 6084: 6082: 6081:Kaitocephalin 6079: 6077: 6074: 6072: 6069: 6067: 6064: 6062: 6059: 6057: 6054: 6051: 6050: 6047: 6044: 6042: 6039: 6037: 6034: 6032: 6029: 6027: 6026:Cyclothiazide 6024: 6020: 6017: 6015: 6012: 6010: 6007: 6005: 6002: 6000: 5997: 5995: 5994:Ibotenic acid 5992: 5990: 5987: 5985: 5982: 5980: 5977: 5975: 5972: 5970: 5967: 5965: 5962: 5960: 5957: 5954: 5951: 5950: 5948: 5943: 5937: 5931: 5928: 5924: 5921: 5919: 5916: 5914: 5911: 5909: 5906: 5904: 5901: 5899: 5896: 5894: 5891: 5889: 5886: 5884: 5881: 5879: 5876: 5874: 5871: 5869: 5866: 5864: 5861: 5858: 5854: 5853:pentobarbital 5850: 5847: 5843: 5840: 5838: 5835: 5833: 5830: 5828: 5825: 5823: 5820: 5818: 5815: 5813: 5810: 5808: 5805: 5803: 5800: 5798: 5795: 5793: 5790: 5788: 5787:Kaitocephalin 5785: 5783: 5780: 5778: 5775: 5773: 5770: 5768: 5765: 5763: 5760: 5758: 5755: 5753: 5750: 5748: 5745: 5743: 5740: 5737: 5736: 5733: 5730: 5728: 5725: 5723: 5720: 5718: 5715: 5713: 5710: 5708: 5705: 5703: 5700: 5698: 5695: 5693: 5690: 5688: 5685: 5683: 5680: 5678: 5675: 5673: 5670: 5668: 5665: 5663: 5660: 5658: 5655: 5653: 5650: 5648: 5645: 5643: 5640: 5638: 5635: 5633: 5630: 5628: 5625: 5623: 5620: 5618: 5615: 5613: 5610: 5608: 5607:Cyclothiazide 5605: 5603: 5600: 5596: 5593: 5591: 5588: 5586: 5583: 5581: 5580:Ibotenic acid 5578: 5576: 5573: 5571: 5568: 5566: 5563: 5561: 5558: 5556: 5553: 5551: 5548: 5545: 5542: 5541: 5539: 5534: 5528: 5524: 5521: 5514: 5509: 5507: 5502: 5500: 5495: 5494: 5491: 5481: 5480: 5476: 5472: 5469: 5463: 5457: 5454: 5452: 5449: 5447: 5444: 5442: 5439: 5436: 5435: 5431: 5427: 5423: 5422:isovaleramide 5419: 5415: 5412: 5410: 5407: 5404: 5400: 5397: 5394: 5390: 5386: 5382: 5379: 5377: 5374: 5372: 5369: 5367: 5364: 5362: 5359: 5357: 5354: 5352: 5349: 5347: 5344: 5342: 5339: 5337: 5334: 5332: 5329: 5327: 5324: 5322: 5319: 5316: 5312: 5308: 5304: 5300: 5297: 5295: 5292: 5290: 5287: 5285: 5282: 5280: 5277: 5275: 5272: 5270: 5267: 5264: 5260: 5259:niflumic acid 5256: 5252: 5248: 5245: 5243: 5240: 5238: 5235: 5233: 5230: 5228: 5225: 5222: 5218: 5214: 5210: 5206: 5203: 5201: 5198: 5196: 5193: 5191: 5188: 5186: 5185:Clomethiazole 5183: 5181: 5180:Chlormezanone 5178: 5176: 5173: 5171: 5170:Carbamazepine 5168: 5165: 5161: 5157: 5153: 5150: 5147: 5143: 5140: 5138: 5135: 5133: 5130: 5128: 5125: 5123: 5120: 5119: 5117: 5113: 5107: 5104: 5102: 5099: 5097: 5094: 5092: 5089: 5087: 5084: 5082: 5079: 5077: 5074: 5072: 5069: 5067: 5064: 5062: 5059: 5057: 5054: 5052: 5049: 5047: 5046:Nitrous oxide 5044: 5042: 5039: 5037: 5034: 5032: 5029: 5027: 5024: 5022: 5019: 5017: 5014: 5012: 5009: 5007: 5004: 5002: 4999: 4997: 4994: 4992: 4989: 4987: 4984: 4982: 4979: 4977: 4976:Diethyl ether 4974: 4972: 4969: 4967: 4964: 4962: 4959: 4957: 4954: 4952: 4949: 4947: 4944: 4942: 4939: 4937: 4934: 4932: 4929: 4927: 4924: 4922: 4919: 4917: 4914: 4912: 4909: 4907: 4904: 4902: 4899: 4897: 4894: 4893: 4891: 4889: 4885: 4881: 4875: 4872: 4870: 4867: 4865: 4862: 4860: 4857: 4855: 4852: 4850: 4847: 4845: 4842: 4840: 4837: 4835: 4832: 4830: 4827: 4826: 4824: 4822: 4818: 4812: 4809: 4807: 4804: 4802: 4799: 4797: 4794: 4793: 4791: 4789: 4785: 4779: 4778:Pyrithyldione 4776: 4774: 4771: 4769: 4766: 4764: 4761: 4760: 4758: 4756: 4752: 4746: 4743: 4741: 4738: 4736: 4733: 4732: 4730: 4728: 4724: 4718: 4715: 4713: 4710: 4708: 4705: 4703: 4700: 4698: 4695: 4693: 4690: 4688: 4685: 4683: 4680: 4678: 4675: 4673: 4670: 4668: 4665: 4663: 4660: 4658: 4655: 4653: 4650: 4648: 4645: 4643: 4640: 4638: 4635: 4633: 4630: 4628: 4625: 4623: 4620: 4618: 4615: 4613: 4610: 4608: 4605: 4603: 4600: 4598: 4595: 4593: 4590: 4588: 4585: 4583: 4580: 4578: 4575: 4573: 4569: 4566: 4565: 4562: 4559: 4557: 4554: 4552: 4549: 4547: 4544: 4542: 4539: 4537: 4534: 4532: 4529: 4527: 4523: 4522: 4518: 4517: 4514: 4511: 4509: 4506: 4504: 4501: 4499: 4496: 4494: 4490: 4489: 4485: 4484: 4481: 4478: 4476: 4473: 4471: 4468: 4466: 4463: 4461: 4458: 4456: 4452: 4451: 4447: 4446: 4444: 4442: 4438: 4432: 4429: 4427: 4424: 4422: 4419: 4417: 4414: 4412: 4409: 4407: 4404: 4402: 4399: 4397: 4394: 4392: 4389: 4387: 4384: 4382: 4379: 4377: 4374: 4372: 4369: 4367: 4364: 4362: 4359: 4357: 4354: 4352: 4349: 4347: 4344: 4342: 4339: 4337: 4334: 4332: 4329: 4327: 4324: 4322: 4319: 4317: 4314: 4312: 4309: 4307: 4303: 4301: 4298: 4296: 4293: 4291: 4288: 4286: 4283: 4281: 4278: 4276: 4273: 4271: 4268: 4267: 4265: 4263: 4259: 4253: 4250: 4248: 4245: 4243: 4240: 4238: 4235: 4233: 4230: 4228: 4225: 4224: 4222: 4220: 4216: 4210: 4207: 4205: 4202: 4200: 4197: 4195: 4192: 4190: 4187: 4185: 4182: 4180: 4177: 4175: 4172: 4170: 4167: 4165: 4162: 4160: 4157: 4155: 4152: 4150: 4147: 4145: 4142: 4140: 4137: 4136: 4134: 4131: 4127: 4121: 4118: 4116: 4113: 4111: 4108: 4107: 4105: 4103: 4099: 4093: 4090: 4087: 4083: 4080: 4078: 4075: 4073: 4070: 4068: 4065: 4063: 4060: 4058: 4055: 4053: 4050: 4048: 4045: 4043: 4040: 4038: 4035: 4033: 4030: 4028: 4025: 4023: 4020: 4019: 4017: 4015: 4011: 4005: 4002: 4000: 3997: 3995: 3992: 3990: 3987: 3985: 3984:Phenprobamate 3982: 3980: 3977: 3975: 3972: 3970: 3967: 3965: 3962: 3960: 3957: 3955: 3952: 3950: 3949:Hexapropymate 3947: 3945: 3942: 3940: 3937: 3935: 3932: 3930: 3927: 3925: 3924:Difebarbamate 3922: 3920: 3917: 3915: 3912: 3910: 3907: 3905: 3902: 3901: 3899: 3897: 3893: 3887: 3884: 3882: 3879: 3877: 3874: 3872: 3869: 3867: 3864: 3862: 3859: 3857: 3854: 3852: 3849: 3847: 3844: 3842: 3839: 3837: 3834: 3832: 3829: 3827: 3824: 3822: 3819: 3817: 3814: 3812: 3809: 3807: 3804: 3802: 3799: 3797: 3794: 3792: 3789: 3787: 3784: 3782: 3779: 3777: 3774: 3772: 3769: 3767: 3764: 3762: 3759: 3757: 3754: 3752: 3749: 3747: 3744: 3742: 3739: 3737: 3736:Nortetrazepam 3734: 3732: 3729: 3727: 3724: 3722: 3719: 3717: 3714: 3712: 3709: 3707: 3704: 3702: 3699: 3697: 3694: 3692: 3689: 3687: 3684: 3682: 3679: 3677: 3674: 3672: 3669: 3667: 3664: 3662: 3659: 3657: 3654: 3652: 3649: 3647: 3644: 3642: 3639: 3637: 3634: 3632: 3629: 3627: 3624: 3622: 3619: 3617: 3614: 3612: 3609: 3607: 3604: 3602: 3599: 3597: 3596:Flutoprazepam 3594: 3592: 3589: 3587: 3584: 3582: 3579: 3577: 3576:Flunitrazolam 3574: 3572: 3571:Flunitrazepam 3569: 3567: 3564: 3562: 3561:Flubromazolam 3559: 3557: 3556:Flubromazepam 3554: 3552: 3549: 3547: 3544: 3542: 3539: 3537: 3534: 3532: 3529: 3527: 3524: 3522: 3519: 3517: 3514: 3512: 3509: 3507: 3504: 3502: 3499: 3497: 3494: 3492: 3489: 3487: 3484: 3482: 3479: 3477: 3474: 3472: 3469: 3467: 3464: 3462: 3459: 3457: 3456:Cloniprazepam 3454: 3452: 3449: 3447: 3444: 3442: 3439: 3437: 3434: 3432: 3429: 3427: 3424: 3422: 3419: 3417: 3414: 3412: 3409: 3407: 3404: 3402: 3399: 3397: 3394: 3392: 3389: 3387: 3384: 3382: 3379: 3377: 3374: 3372: 3369: 3367: 3364: 3362: 3359: 3357: 3354: 3352: 3349: 3347: 3346:2-Oxoquazepam 3344: 3343: 3341: 3339: 3335: 3329: 3326: 3324: 3321: 3319: 3316: 3314: 3311: 3309: 3306: 3304: 3301: 3299: 3296: 3294: 3291: 3289: 3288:Thialbarbital 3286: 3284: 3283:Tetrabarbital 3281: 3279: 3276: 3274: 3271: 3269: 3268:Spirobarbital 3266: 3264: 3261: 3259: 3256: 3254: 3251: 3249: 3248:Proxibarbital 3246: 3244: 3241: 3239: 3238:Propallylonal 3236: 3234: 3231: 3229: 3226: 3224: 3221: 3219: 3218:Phenobarbital 3216: 3214: 3211: 3209: 3208:Pentobarbital 3206: 3204: 3201: 3199: 3198:Narcobarbital 3196: 3194: 3191: 3189: 3186: 3184: 3181: 3179: 3176: 3174: 3171: 3169: 3166: 3164: 3163:Heptobarbital 3161: 3159: 3156: 3154: 3151: 3149: 3146: 3144: 3141: 3139: 3136: 3134: 3133:Difebarbamate 3131: 3129: 3126: 3124: 3123:Cyclobarbital 3121: 3119: 3116: 3114: 3111: 3109: 3106: 3104: 3101: 3099: 3096: 3094: 3091: 3089: 3086: 3084: 3081: 3079: 3076: 3074: 3071: 3069: 3068:Benzobarbital 3066: 3064: 3061: 3059: 3056: 3054: 3051: 3049: 3046: 3044: 3041: 3039: 3036: 3034: 3031: 3030: 3028: 3026: 3022: 3016: 3013: 3011: 3008: 3006: 3003: 3001: 2998: 2996: 2994: 2990: 2988: 2986: 2982: 2980: 2977: 2975: 2972: 2970: 2967: 2965: 2962: 2960: 2957: 2955: 2952: 2950: 2947: 2945: 2942: 2940: 2939:Ethchlorvynol 2937: 2934: 2930: 2927: 2925: 2922: 2920: 2917: 2915: 2912: 2910: 2907: 2906: 2904: 2902: 2898: 2894: 2881: 2876: 2874: 2869: 2867: 2862: 2861: 2858: 2842: 2840: 2837: 2836: 2834: 2831: 2828: 2825: 2823: 2820: 2819: 2815: 2809: 2806: 2804: 2801: 2799: 2796: 2794: 2791: 2789: 2786: 2784: 2781: 2779: 2778:Phenaglycodol 2776: 2774: 2771: 2769: 2766: 2764: 2761: 2759: 2756: 2754: 2751: 2749: 2746: 2744: 2741: 2739: 2736: 2734: 2731: 2729: 2726: 2725: 2723: 2719: 2712: 2708: 2707:Beta blockers 2705: 2702: 2698: 2694: 2690: 2687: 2684: 2680: 2677: 2676: 2674: 2670: 2664: 2660: 2654: 2651: 2649: 2646: 2645: 2643: 2641: 2637: 2631: 2628: 2626: 2623: 2621: 2618: 2616: 2613: 2611: 2608: 2604: 2597: 2592: 2589: 2582: 2577: 2574: 2567: 2562: 2559: 2552: 2547: 2544: 2537: 2532: 2529: 2522: 2517: 2516: 2514: 2512: 2508: 2502: 2499: 2497: 2494: 2492: 2489: 2487: 2484: 2483: 2481: 2477: 2474: 2459: 2455: 2449: 2446: 2445: 2443: 2441: 2437: 2431: 2428: 2426: 2423: 2421: 2420:Chlormezanone 2418: 2416: 2413: 2410: 2406: 2403: 2400: 2399:phenobarbital 2396: 2393: 2391: 2388: 2384: 2381: 2379: 2376: 2374: 2371: 2369: 2366: 2364: 2361: 2359: 2356: 2354: 2351: 2349: 2346: 2344: 2341: 2339: 2336: 2334: 2331: 2329: 2326: 2324: 2321: 2319: 2316: 2314: 2311: 2309: 2306: 2304: 2301: 2299: 2296: 2294: 2291: 2289: 2286: 2284: 2281: 2279: 2276: 2274: 2270: 2269: 2267: 2262: 2254: 2244: 2238: 2235: 2233: 2230: 2228: 2225: 2224: 2222: 2220: 2214: 2204: 2199: 2195: 2188: 2183: 2181: 2176: 2174: 2169: 2168: 2165: 2159: 2156: 2153: 2150: 2147: 2144: 2143: 2139: 2131: 2127: 2123: 2119: 2112: 2109: 2099: 2093: 2090: 2080: 2074: 2071: 2066: 2062: 2056: 2053: 2048: 2044: 2037: 2034: 2029: 2023: 2020: 2015: 2011: 2007: 2003: 2000:(5): 501–15. 1999: 1995: 1988: 1985: 1980: 1976: 1972: 1971:"Meprobamate" 1966: 1963: 1958: 1952: 1948: 1947: 1939: 1936: 1931: 1927: 1923: 1919: 1916:(3): 359–62. 1915: 1911: 1904: 1901: 1896: 1892: 1888: 1884: 1880: 1876: 1869: 1866: 1861: 1857: 1852: 1847: 1843: 1839: 1835: 1831: 1827: 1820: 1817: 1812: 1808: 1804: 1800: 1796: 1789: 1787: 1783: 1778: 1777:Health Canada 1774: 1768: 1765: 1750: 1744: 1741: 1729: 1728: 1723: 1717: 1714: 1702: 1701: 1696: 1690: 1687: 1676: 1675: 1670: 1663: 1660: 1655: 1653:9781305537231 1649: 1645: 1638: 1635: 1624: 1620: 1614: 1611: 1606: 1602: 1598: 1596:9780786727476 1592: 1588: 1581: 1578: 1566: 1565: 1560: 1554: 1551: 1540: 1539: 1534: 1527: 1524: 1512: 1511: 1506: 1500: 1497: 1493:. p. 21. 1492: 1491: 1486: 1479: 1476: 1471: 1467: 1466:"Meprobamate" 1461: 1458: 1453: 1447: 1443: 1442: 1434: 1431: 1426: 1422: 1418: 1414: 1413:J Am Chem Soc 1407: 1404: 1399: 1395: 1390: 1385: 1381: 1377: 1374:(3): 335–44. 1373: 1369: 1365: 1358: 1355: 1350: 1346: 1341: 1336: 1332: 1328: 1325:(4): 241–50. 1324: 1320: 1316: 1309: 1306: 1301: 1297: 1292: 1287: 1283: 1279: 1275: 1271: 1267: 1260: 1257: 1252: 1248: 1244: 1238: 1234: 1233: 1225: 1222: 1210: 1206: 1202: 1198: 1192: 1189: 1183: 1179: 1178:Phenprobamate 1176: 1174: 1171: 1169: 1166: 1164: 1161: 1159: 1156: 1155: 1151: 1149: 1147: 1143: 1139: 1135: 1126: 1119: 1117: 1114: 1111: 1106: 1104: 1100: 1095: 1093: 1089: 1085: 1081: 1077: 1073: 1069: 1065: 1058:Health issues 1057: 1055: 1053: 1049: 1043: 1038: 1033: 1029: 1026: 1024: 1020: 1015: 1008: 1006: 1004: 1003:methocarbamol 1000: 996: 992: 991:phenprobamate 988: 984: 980: 976: 972: 968: 964: 960: 956: 948: 947:limbic system 944: 939: 937: 933: 929: 921: 919: 916: 912: 907: 904: 902: 898: 897: 892: 891: 886: 881: 877: 875: 874:Elvis Presley 870: 865: 863: 862:Aldous Huxley 859: 858:New York City 855: 850: 846: 845:tranquilizers 842: 837: 833: 829: 825: 820: 818: 813: 808: 806: 801: 797: 793: 786: 784: 782: 778: 774: 770: 766: 762: 758: 754: 750: 747:—marketed as 746: 736: 729: 720: 715: 711: 704: 695: 691: 684: 680: 678: 677:Boiling point 674: 670: 668: 667:Melting point 664: 660: 658: 654: 647: 643: 642: 640: 637: 632: 625: 623: 619: 592: 590: 586: 581: 577: 573: 570: 568: 566:ECHA InfoCard 562: 554: 550: 549:DTXSID3023261 546: 545: 543: 534: 530: 523: 519: 518: 516: 514: 510: 503: 499: 498: 496: 494: 490: 483: 479: 478: 476: 474: 470: 463: 459: 458: 456: 454: 450: 443: 439: 438: 436: 434: 430: 423: 419: 418: 416: 414: 410: 403: 399: 398: 396: 389: 385: 378: 374: 373: 371: 369: 365: 356: 352: 345: 340: 337: 334: 332: 328: 324: 322: 315: 312: 309: 307: 303: 299: 297: 293: 289: 285: 279: 269: 267: 257: 254: 245: 243: 234: 231: 221: 218: 208: 207: 205: 203: 199: 194: 186: 181: 178: 177: 175: 173: 169: 165: 163: 157: 151: 142: 141: 139: 137: 131: 127: 123: 121: 117: 113: 109: 107: 103: 99: 95: 91: 87: 83: 79: 75: 72: 70: 66: 63:Clinical data 61: 57: 52: 48: 43: 33: 19: 7526: 7519: 7510: 7509: 7493: 7490: 7362: 7269:Cyclopropane 7250: 7233: 7211: 7147: 7099:Propoxyphene 7069:Orphenadrine 6974:Ketobemidone 6939:Eticyclidine 6874:Coronaridine 6859:ARL-15896-AR 6775: 6743: 6719: 6655:-Cycloserine 6637:Carisoprodol 6593: 6481: 6479:Antagonists: 6478: 6411: 6406: 6389: 6317:-Cycloserine 6258: 6197: 6194: 6138:Barbiturates 6134: 6111:Selurampanel 6066:Dasolampanel 6053:Antagonists: 6052: 6022: 5955: 5952: 5926: 5863:Cyclopropane 5849:Barbiturates 5845: 5817:Selurampanel 5767:Dasolampanel 5739:Antagonists: 5738: 5722:Pramiracetam 5598: 5546: 5543: 5467: 5466: 5437: 5294:Lavender oil 5036:Nitric oxide 4956:Cryofluorane 4901:Acetophenone 4859:Methaqualone 4854:Mecloqualone 4849:Mebroqualone 4839:Diproqualone 4834:Cloroqualone 4763:Glutethimide 4567: 4519: 4486: 4448: 4421:Testosterone 4386:Progesterone 4351:Hydroxydione 4300:Androsterone 4227:Acecarbromal 4132:constituents 3968: 3919:Cyclarbamate 3909:Carisoprodol 3681:Metaclazepam 3676:Menitrazepam 3666:Meclonazepam 3661:Lormetazepam 3591:Flutemazepam 3416:Ciclotizolam 3406:Carburazepam 3298:Thiobarbital 3258:Secobarbital 3223:Phetharbital 3203:Nealbarbital 3188:Methohexital 3173:Hexobarbital 3108:Butallylonal 3103:Butobarbital 3058:Barbexaclone 3053:Aprobarbital 3038:Allobarbital 3025:Barbiturates 2992: 2984: 2974:Petrichloral 2748:Lorpiprazole 2738:Fabomotizole 2728:Benzoctamine 2630:Vortioxetine 2606: 2573:clomipramine 2528:escitalopram 2415:Carisoprodol 2408: 2395:Barbiturates 2386: 2271: 2237:Tandospirone 2121: 2117: 2111: 2092: 2073: 2064: 2055: 2046: 2036: 2030:. July 2023. 2022: 1997: 1993: 1987: 1979:the original 1974: 1965: 1945: 1938: 1913: 1909: 1903: 1878: 1874: 1868: 1833: 1829: 1819: 1802: 1798: 1776: 1767: 1756:. Retrieved 1754:. 2012-01-19 1743: 1732:. Retrieved 1730:. 1967-12-06 1725: 1716: 1705:. Retrieved 1703:. 1965-04-22 1698: 1689: 1678:. Retrieved 1672: 1662: 1643: 1637: 1626:. Retrieved 1622: 1613: 1586: 1580: 1569:. Retrieved 1567:. 1956-10-19 1562: 1553: 1542:. Retrieved 1536: 1526: 1515:. Retrieved 1508: 1499: 1488: 1478: 1469: 1460: 1440: 1433: 1416: 1412: 1406: 1371: 1367: 1357: 1322: 1318: 1308: 1273: 1269: 1259: 1231: 1224: 1213:. Retrieved 1191: 1163:Carisoprodol 1134:formaldehyde 1131: 1115: 1110:carisoprodol 1107: 1096: 1072:barbiturates 1061: 1044: 1042: 1027: 1016: 1012: 979:carisoprodol 940: 928:barbiturates 925: 922:Pharmacology 908: 905: 894: 888: 882: 878: 869:Milton Berle 866: 832:hydrotherapy 821: 809: 799: 792:Frank Berger 790: 756: 748: 744: 743: 732:   318:Elimination 202:Legal status 196:Legal status 93: 89: 85: 81: 77: 73: 7565:Anxiolytics 7459:Pentamidine 7444:Minocycline 7424:Hodgkinsine 7394:Dexanabinol 7324:Sevoflurane 7178:Isoxsuprine 7173:Haloperidol 7153:Besonprodil 7114:Rimantadine 7064:Norketamine 7059:Noribogaine 7034:Milnacipran 6999:Levorphanol 6949:Gacyclidine 6919:Dizocilpine 6914:Diphenidine 6904:Dextrorphan 6824:Alaproclate 6767:Huperzine A 6720:Meprobamate 6680:Harkoseride 6575:Perzinfotel 6452:Plazinemdor 5999:Kainic acid 5984:Domoic acid 5930:Minocycline 5918:Sevoflurane 5595:Willardiine 5570:Domoic acid 5376:Stiripentol 5371:Seproxetine 5341:Niacinamide 5321:Loreclezole 5142:Avermectins 5106:Vinyl ether 5076:Sevoflurane 5056:Paraldehyde 5006:Halopropane 4829:Afloqualone 4811:Tracazolate 4806:ICI-190,622 4796:Cartazolate 4773:Piperidione 4768:Methyprylon 4735:Fospropofol 4657:Pipequaline 4465:Pazinaclone 4455:Eszopiclone 4311:Cholesterol 4295:Androstenol 4219:Monoureides 4199:Methysticin 3999:Tetrabamate 3979:Pentabamate 3969:Meprobamate 3939:Febarbamate 3904:Carisbamate 3856:Triflubazam 3846:Tolufazepam 3806:Rilmazafone 3801:Remimazolam 3776:Proflazepam 3761:Pivoxazepam 3721:Nitrazepate 3711:Nimetazepam 3646:Lopirazepam 3616:Haloxazolam 3566:Fludiazepam 3511:Doxefazepam 3486:Delorazepam 3466:Clotiazepam 3461:Clorazepate 3426:Cinolazepam 3323:Vinbarbital 3278:Tetrabamate 3233:Probarbital 3213:Phenallymal 3178:Metharbital 3153:Febarbamate 3048:Amobarbital 2949:Isopropanol 2919:Chloralodol 2829:from market 2758:Mepiprazole 2743:Hydroxyzine 2733:Cycloserine 2711:propranolol 2653:Flupentixol 2610:Agomelatine 2588:mirtazapine 2409:meprobamate 2343:Fludiazepam 2318:Clotiazepam 2313:Clorazepate 2194:Anxiolytics 1173:Pentabamate 1064:Schedule IV 1009:Indications 967:spinal cord 860:, at which 745:Meprobamate 629: g·mol 572:100.000.306 342:Identifiers 278:Schedule IV 242:Schedule IV 120:MedlinePlus 69:Trade names 39:Meprobamate 7570:Carbamates 7544:Categories 7497:AGN-241751 7469:Piretanide 7419:Furosemide 7404:Flupirtine 7381:Conantokin 7376:Caroverine 7371:Bumetanide 7304:Isoflurane 7274:Desflurane 7264:Chloroform 7203:Safaprodil 7198:Ro 25-6981 7139:Tiletamine 7124:Sabeluzole 7104:Remacemide 7049:Neramexane 7019:Methorphan 7004:Loperamide 6979:Lanicemine 6964:Indantadol 6929:Esketamine 6924:Ephenidine 6884:Dexoxadrol 6849:Arketamine 6834:Amantadine 6794:3-MeO-PCMo 6772:Putrescine 6715:MDL-105519 6690:Kynurenine 6670:Gavestinel 6585:SDZ-220581 6545:MDL-100453 6428:prasterone 6398:Spermidine 6371:Milacemide 6276:ACC (ACPC) 6162:Evans blue 6126:Topiramate 6116:Tezampanel 6046:Isoflurane 5923:Talampanel 5908:Perampanel 5903:Isoflurane 5888:GYKI-53655 5883:GYKI-52466 5878:Evans blue 5842:Zonampanel 5832:Topiramate 5822:Tezampanel 5797:Kynurenine 5757:Caroverine 5752:Becampanel 5702:Oxiracetam 5602:Aniracetam 5523:modulators 5409:Topiramate 5399:Terpenoids 5356:Propanidid 5346:Org 25,435 5274:Flupirtine 5269:Fluoxetine 5175:Chloralose 5146:ivermectin 5051:Norflurane 5016:Isoflurane 4961:Desflurane 4951:Chloroform 4911:Aliflurane 4844:Etaqualone 4672:SB-205,384 4602:CP-615,003 4597:CL-218,872 4551:Panadiplon 4541:Lorediplon 4470:Suproclone 4431:Zuranolone 4391:Renanolone 4376:Posovolone 4356:Minaxolone 4346:Ganaxolone 4285:Alfaxalone 4280:Alfadolone 4270:Acebrochol 4237:Bromisoval 4115:Metomidate 4102:Imidazoles 4062:Hispidulin 4014:Flavonoids 3974:Nisobamate 3964:Mebutamate 3934:Ethinamate 3929:Emylcamate 3896:Carbamates 3866:Tuclazepam 3841:Tetrazepam 3796:Reclazepam 3771:Premazepam 3751:Phenazepam 3731:Nordazepam 3726:Nitrazolam 3716:Nitrazepam 3696:Motrazepam 3651:Loprazolam 3641:Lofendazam 3626:Imidazenil 3586:Flutazolam 3581:Flurazepam 3551:Fletazepam 3506:Dimdazenil 3501:Diclazepam 3481:Cyprazepam 3471:Cloxazolam 3451:Clonazolam 3446:Clonazepam 3436:Climazolam 3396:Brotizolam 3391:Bromazolam 3386:Bromazepam 3381:Bretazenil 3376:Bentazepam 3366:Arfendazam 3361:Alprazolam 3356:Adinazolam 3328:Vinylbital 3308:Thiopental 3183:Methitural 3098:Buthalital 3093:Butalbital 2944:Isobutanol 2773:Oxaflozane 2701:guanfacine 2648:Quetiapine 2625:Vilazodone 2620:Tianeptine 2603:phenelzine 2543:duloxetine 2501:Pregabalin 2486:Gabapentin 2405:Carbamates 2368:Nordazepam 2323:Cloxazolam 2308:Clonazepam 2288:Bromazepam 2283:Alprazolam 2278:Adinazolam 1836:: 149–58. 1758:2012-01-20 1734:2009-02-01 1707:2009-02-01 1680:2009-02-01 1628:2018-09-22 1571:2009-02-01 1544:2009-01-23 1517:2009-01-23 1215:2023-08-16 1184:References 999:mebutamate 796:mephenesin 769:anxiolytic 634:3D model ( 622:Molar mass 482:9I7LNY769Q 453:ChemSpider 413:IUPHAR/BPS 368:CAS Number 351:IUPAC name 306:Metabolism 7555:Hypnotics 7550:Sedatives 7511:See also: 7491:Unsorted: 7434:MDL-27266 7414:FR-115427 7409:FPL-12495 7366:ARR-15896 7294:Halothane 7284:Enflurane 7242:Magnesium 7193:Ro 8-4304 7168:Eliprodil 7079:PD-137889 7039:Morphanol 7014:Methadone 7009:Memantine 6959:Ibogamine 6934:Etoxadrol 6864:ARL-16247 6854:ARL-12495 6839:Aptiganel 6804:4-MeO-PCP 6799:3-MeO-PCP 6789:3-MeO-PCE 6752:Co 101676 6725:MRZ 2/576 6675:GV-196771 6665:Felbamate 6642:CGP-39653 6622:ACEA-1328 6617:ACEA-1011 6560:NPC-17742 6555:NPC-12626 6540:LY-274614 6535:LY-235959 6530:LY-233053 6515:CGS-19755 6510:CGP-40116 6505:CGP-39653 6500:CGP-39551 6495:CGP-37849 6485:AP5 (APV) 6386:Sarcosine 6262:β-Fluoro- 6211:Glutamate 6206:Aspartate 6195:Agonists: 6152:Enflurane 6096:LY-382884 6056:ACEA-1011 6041:Halothane 6036:Enflurane 6031:Diazoxide 6004:LY-339434 5989:Glutamate 5953:Agonists: 5898:Irampanel 5893:Halothane 5868:Enflurane 5742:ACEA-1011 5717:Piracetam 5697:ORG-26576 5692:Nooglutyl 5682:LY-503430 5677:LY-451646 5672:LY-404187 5667:LY-395153 5662:LY-392098 5647:Diazoxide 5575:Glutamate 5544:Agonists: 5468:See also: 5430:valerenol 5351:Phenytoin 5331:Monastrol 5289:Lanthanum 5284:KRM-II-81 5247:Fenamates 5242:Etifoxine 5237:Etazepine 5232:Efavirenz 5190:Darigabat 5086:Teflurane 5071:Roflurane 5066:Propylene 5011:Halothane 4996:Fluroxene 4981:Enflurane 4884:Volatiles 4801:Etazolate 4712:Viqualine 4667:RWJ-51204 4632:L-838,417 4622:Imepitoin 4592:CGS-20625 4587:CGS-13767 4572:Adipiplon 4546:Ocinaplon 4508:Saripidem 4503:Necopidem 4480:Zopiclone 4475:Suriclone 4460:Pagoclone 4366:ORG-21465 4361:ORG-20599 4252:Ectylurea 4242:Carbromal 4120:Propoxate 4110:Etomidate 4037:Baicalein 3994:Styramate 3989:Procymate 3959:Lorbamate 3944:Felbamate 3914:Clocental 3886:Zomebazam 3881:Zolazepam 3876:Zapizolam 3871:Uldazepam 3851:Triazolam 3836:Temazepam 3831:Sulazepam 3821:Ro48-8684 3816:Ro48-6791 3811:Ripazepam 3781:Pyrazolam 3756:Pinazepam 3706:Nifoxipam 3691:Midazolam 3686:Mexazolam 3671:Medazepam 3656:Lorazepam 3636:Ketazolam 3631:Irazepine 3621:Iclazepam 3611:Halazepam 3606:Gidazepam 3601:Fosazepam 3521:Estazolam 3516:Elfazepam 3491:Demoxepam 3421:Cinazepam 3401:Camazepam 3371:Avizafone 3293:Thiamylal 3228:Primidone 3158:Heptabarb 3148:Eterobarb 3113:Carbubarb 3010:Triclofos 2909:Brometone 2839:Phase III 2827:Withdrawn 2808:Validolum 2803:Tofisopam 2798:Tiagabine 2788:Picamilon 2768:Opipramol 2693:clonidine 2615:Bupropion 2558:trazodone 2448:Zopiclone 2440:Hypnotics 2430:Etifoxine 2378:Pinazepam 2363:Medazepam 2358:Lorazepam 2353:Ketazolam 2348:Halazepam 2293:Camazepam 2227:Buspirone 1623:CBC Radio 1605:302287405 1168:Lorbamate 1138:carbamate 1120:Synthesis 1103:Bruce Lee 1092:methadone 1084:gabaergic 1019:Equagesic 995:felbamate 955:receptors 765:carbamate 522:ChEMBL979 358:carbamate 331:Excretion 320:half-life 253:Anlage II 160:Routes of 134:Pregnancy 112:Monograph 106:Drugs.com 94:Zirponand 86:Amepromat 82:Meprospan 7439:Metaphit 7349:Urethane 7237:Hydrogen 7234:Cations: 7144:Tramadol 6969:Ketamine 6954:Ibogaine 6869:Budipine 6784:3-HO-PCP 6710:LU-73068 6700:L-701324 6695:L-689560 6602:5,7-DCKA 6590:Selfotel 6472:SAGE-718 6467:SAGE-301 6462:SAGE-201 6403:Spermine 6393:Neomycin 6358:-Alanine 6350:L-687414 6309:-Alanine 6266:-alanine 6255:Theanine 6121:Theanine 6019:SYM-2081 5827:Theanine 5456:TCS-1205 5451:TCS-1105 5441:α-Pinene 5414:Valerian 5389:tetronal 5366:Safranal 5315:obovatol 5311:magnolol 5307:honokiol 5137:Alogabat 5132:AA-29504 5081:Synthane 5041:Nitrogen 5021:Kerosine 5001:Gasoline 4991:Ethylene 4931:Centalun 4926:Butylene 4740:Propofol 4702:U-89843A 4682:TGSC01AA 4652:NS-11394 4617:GBLD-345 4582:CGS-9896 4577:CGS-8216 4561:Zaleplon 4556:Taniplon 4536:Indiplon 4531:Fasiplon 4526:Divaplon 4513:Zolpidem 4416:SAGE-872 4411:SAGE-689 4406:SAGE-516 4401:SAGE-324 4396:SAGE-105 4304:Certain 4247:Capuride 4209:Yangonin 4086:baicalin 4082:Skullcap 4072:Luteolin 4047:Catechin 4042:Baicalin 4032:Apigenin 4004:Tybamate 3791:Quazepam 3786:QH-II-66 3766:Prazepam 3746:Oxazolam 3741:Oxazepam 3541:Etizolam 3496:Diazepam 3476:CP-1414S 3441:Clobazam 3431:Clazolam 3318:Valofane 3273:Talbutal 3263:Sigmodal 3168:Hexethal 3063:Barbital 3043:Alphenal 3033:(-)-DMBB 2979:Propanol 2969:Pentanol 2959:Methanol 2901:Alcohols 2783:Phenibut 2763:Nicotine 2683:prazosin 2496:Phenibut 2476:blockers 2383:Prazepam 2373:Oxazepam 2338:Etizolam 2328:Diazepam 2303:Clobazam 2232:Gepirone 2219:agonists 2047:The Wrap 1860:26872987 1538:Newsweek 1398:17117615 1349:19108125 1300:19108096 1251:52286331 1209:Archived 1152:See also 1142:phosgene 1088:diazepam 987:prodrugs 983:tybamate 943:thalamus 885:sedative 817:Milltown 735:(verify) 433:DrugBank 325:10 hours 230:Class B1 172:ATC code 136:category 7483:saffron 7329:Toluene 7319:Octanol 7299:Hexanol 7254:Benzene 7230:TCN-213 7225:TCN-201 7220:MPX-007 7215:MPX-004 6809:8A-PDHQ 6747:Arcaine 6740:ZD-9379 6437:sulfate 6366:-Serine 6340:Glycine 6325:-Serine 6240:Proline 6167:NS-3763 6140:(e.g., 6131:UBP-302 6009:Proline 5851:(e.g., 5727:S-18986 5657:IDRA-21 5642:CX-1942 5637:CX-1739 5585:Proline 5403:borneol 5401:(e.g., 5393:trional 5383:(e.g., 5301:(e.g., 5299:Lignans 5249:(e.g., 5207:(e.g., 5152:Bromide 5144:(e.g., 5127:α-EMTBL 5091:Toluene 5061:Propane 4936:Chloral 4916:Benzene 4896:Acetone 4727:Phenols 4717:Y-23684 4707:U-90042 4692:TPA-023 4677:SX-3228 4662:ROD-188 4647:NS-2710 4642:NS-2664 4627:JM-1232 4612:ELB-139 4607:CTP-354 4493:Alpidem 4092:Wogonin 4067:Linarin 3546:FG-8205 3253:Reposal 2954:Menthol 2914:Butanol 2753:Mebicar 2709:(e.g., 2691:(e.g., 2681:(e.g., 2607:Others: 2601:(e.g., 2586:(e.g., 2571:(e.g., 2556:(e.g., 2541:(e.g., 2526:(e.g., 2407:(e.g., 2397:(e.g., 2390:Alpidem 2387:Others: 1930:4085561 1895:6468504 1851:4806799 1811:9067327 1389:3181823 1340:1509790 1291:1509753 1146:ammonia 1076:alcohol 971:alcohol 961:in the 787:History 757:Equanil 749:Miltown 657:Density 627:218.253 589:Formula 442:DB00371 388:PubChem 377:57-53-4 311:Hepatic 266:Class C 251:: 240:: 188:) 182: ( 180:N05BC01 149: C 126:a682077 78:Equanil 74:Miltown 18:Miltown 7359:Xylene 7259:Butane 6632:AV-101 6345:HA-966 5632:CX-717 5622:CX-614 5617:CX-546 5612:CX-516 5336:Niacin 4921:Butane 4874:SL-164 4745:Thymol 4687:TP-003 4568:Others 4371:P1-185 4331:5β-DHP 4326:5α-DHP 4321:3α-DHP 4169:Kavain 4077:Rc-OMe 2822:WHO-EM 2793:Selank 2721:Others 2104:  2085:  2065:Gov.UK 2014:608316 2012:  1953:  1928:  1893:  1858:  1848:  1809:  1650:  1603:  1593:  1448:  1396:  1386:  1347:  1337:  1298:  1288:  1249:  1239:  1197:Anvisa 1048:bezoar 1001:, and 690:SMILES 513:ChEMBL 502:D00376 276: 264: 228: 215: 90:Quivet 7354:Xenon 6814:18-MC 6779:2-MDP 6607:7-CKA 6570:PEAQX 6296:B6B21 6286:AK-51 6220:-HCA) 6183:NMDAR 6106:NS102 5837:YM90K 5532:AMPAR 5195:DEABL 4888:gases 4697:TP-13 4426:THDOC 4316:DHDOC 2595:MAOIs 2580:TeCAs 2550:SARIs 2535:SNRIs 2520:SSRIs 1752:(PDF) 761:Wyeth 710:InChI 636:JSmol 336:Renal 7449:MPEP 7389:-αAA 7247:Zinc 7074:PCPr 7044:NEFA 6730:PNQX 6660:DNQX 6647:CNQX 6580:PPDA 6565:PBPD 6435:DHEA 6420:DHEA 6330:DHPG 6281:ACPD 6271:ACBD 6235:NMDA 6201:AMAA 6101:NBQX 6076:GAMS 6071:DNQX 6061:CNQX 5979:ATPA 5974:AMPA 5812:PNQX 5807:NBQX 5782:GAMS 5772:DNQX 5762:CNQX 5747:ATPO 5707:PEPA 5565:BOAA 5560:AMPA 4498:DS-1 4130:Kava 4057:EGCG 2993:tert 2985:tert 2888:GABA 2565:TCAs 2472:VDCC 2260:PAMs 2248:GABA 2208:5-HT 2198:N05B 2010:PMID 1951:ISBN 1926:PMID 1891:PMID 1856:PMID 1807:PMID 1648:ISBN 1601:OCLC 1591:ISBN 1446:ISBN 1394:PMID 1345:PMID 1296:PMID 1247:OCLC 1237:ISBN 1144:and 1074:and 981:and 965:and 951:GABA 945:and 755:and 493:KEGG 473:UNII 462:3924 422:7225 402:4064 290:data 166:Oral 102:AHFS 6612:ACC 6520:CPP 6490:AP7 6301:CCG 5941:KAR 5227:DS2 4336:DHT 4052:EGC 2605:); 2126:doi 2002:doi 1918:doi 1914:118 1883:doi 1879:101 1846:PMC 1838:doi 1834:775 1803:280 1421:doi 1384:PMC 1376:doi 1335:PMC 1327:doi 1286:PMC 1278:doi 856:in 826:in 759:by 751:by 538:EPA 392:CID 185:WHO 7546:: 7361:; 7249:; 7232:; 7210:; 7146:; 6774:; 6742:; 6592:; 6410:24 6405:; 6388:; 6257:; 6144:, 6133:; 6021:; 5925:; 5855:, 5844:; 5597:; 5477:• 5473:• 5428:, 5424:, 5420:, 5391:, 5387:, 5313:, 5309:, 5305:, 5261:, 5257:, 5253:, 5219:, 5215:, 5211:, 5162:, 5158:, 4570:: 4524:: 4491:: 4453:: 2835:: 2699:, 2695:, 2385:; 2210:1A 2122:73 2120:. 2063:. 2045:. 2008:. 1998:11 1996:. 1973:. 1924:. 1912:. 1889:. 1877:. 1854:. 1844:. 1832:. 1828:. 1801:. 1797:. 1785:^ 1775:. 1724:. 1697:. 1671:. 1621:. 1599:. 1561:. 1535:. 1507:. 1487:. 1468:. 1417:73 1415:. 1392:. 1382:. 1370:. 1366:. 1343:. 1333:. 1321:. 1317:. 1294:. 1284:. 1272:. 1268:. 1245:. 1148:. 1025:. 1005:. 997:, 993:, 938:. 876:. 603:18 272:US 260:UK 248:DE 237:CA 224:BR 217:S4 211:AU 145:AU 92:, 88:, 84:, 80:, 76:, 7485:) 7481:( 7387:D 6653:D 6443:) 6439:( 6430:) 6426:( 6412:S 6364:L 6356:L 6323:D 6315:D 6307:D 6264:D 6218:L 6148:) 5859:) 5512:e 5505:t 5498:v 5432:) 5405:) 5395:) 5317:) 5265:) 5223:) 5166:) 5148:) 4886:/ 4088:) 2935:) 2931:( 2891:A 2879:e 2872:t 2865:v 2713:) 2703:) 2685:) 2671:) 2667:( 2590:) 2575:) 2560:) 2545:) 2530:) 2478:) 2469:δ 2467:2 2465:α 2462:( 2411:) 2401:) 2275:: 2252:R 2250:A 2212:R 2200:) 2196:( 2186:e 2179:t 2172:v 2154:. 2148:. 2132:. 2128:: 2049:. 2016:. 2004:: 1959:. 1932:. 1920:: 1897:. 1885:: 1862:. 1840:: 1813:. 1761:. 1737:. 1710:. 1683:. 1656:. 1631:. 1607:. 1574:. 1547:. 1520:. 1454:. 1427:. 1423:: 1400:. 1378:: 1372:8 1351:. 1329:: 1323:2 1302:. 1280:: 1274:1 1253:. 1218:. 1078:( 985:( 953:A 638:) 615:4 612:O 609:2 606:N 600:H 597:9 594:C 540:) 536:( 300:? 274:: 262:: 226:: 213:: 147:: 104:/ 34:. 20:)

Index

Miltown
Milltown (disambiguation)


Trade names
AHFS
Drugs.com
Monograph
MedlinePlus
a682077
Pregnancy
category

Routes of
administration

ATC code
N05BC01
WHO
Legal status
S4
Class B1
Schedule IV
Anlage II
Class C
Schedule IV
Pharmacokinetic
Bioavailability
Metabolism
Hepatic
Elimination half-life
Excretion
Renal
IUPAC name

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