492:
49:
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McKay L, Renoir JM, Weigel NL, Wilson EM, McDonnell DP, Cidlowski JA. (2006) International Union of
Pharmacology. LXV. The pharmacology and classification of the nuclear receptor superfamily: glucocorticoid, mineralocorticoid, progesterone, and androgen receptors. Pharmacol Rev.
356:) have similar affinity for the mineralocorticoid receptor; however, glucocorticoids circulate at roughly 100 times the level of mineralocorticoids. An enzyme exists in mineralocorticoid target tissues to prevent overstimulation by glucocorticoids. This enzyme,
2925:
273:, showing mineralocorticoids in ellipse at top right. Note that it is not a strictly bounded group, but a continuum of structures with increasing mineralocorticoid effect, with the primary example aldosterone at top.
3285:
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Stewart P (2008): "The
Adrenal Cortex " In: Kronenberg, Melmed, Polonsky, Larsen (eds.) Williams Textbook of Endocrinology (11 ed)., Saunders Elsevier, Philadelphia, pp. 445–504.
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2911:
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Bennett PN and Brown MJ (2008) "Adrenal corticosteroids, antagonists, corticotropin", in
Clinical Pharmacology (10ed), Churchill Livingstone Elsevier, Publ. pp. 593–607.
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Omar, HR; Komarova, I; El-Ghonemi, M; Fathy, A; Rashad, R; Abdelmalak, HD; Yerramadha, MR; Ali, Y; Helal, E; Camporesi, EM (2012).
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Pippal JB, Fuller PJ. (2008) Structure-function relationships in the mineralocorticoid receptor. J Mol
Endocrinol. 41(6):405-13.
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2019:
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383:(the syndrome caused by elevated aldosterone) is commonly caused by either idiopathic adrenal hyperplasia or by an
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Aldosterone acts on the kidneys to provide active reabsorption of sodium and an associated passive reabsorption of
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The name mineralocorticoid derives from early observations that these hormones were involved in the retention of
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412:(the syndrome caused by underproduction of aldosterone) leads to the salt-wasting state associated with
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is known to be an inhibitor of this enzyme and chronic consumption can result in a condition known as
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Hu X, Funder JW (2006) The evolution of mineralocorticoid receptors. Mol
Endocrinol. 20(7):1471-8.
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as well as by fast nongenomic mechanisms through membrane-associated receptors and
225:
182:
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The effects of mineralocorticoids are mediated by slow genomic mechanisms through
17:
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and other disease states may also cause this situation. Acute underproduction (
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binding. After a hormone binds to the corresponding receptor, the newly formed
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405:(K+). With extreme K+ loss there is muscle weakness and eventually paralysis.
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364:), catalyzes the deactivation of glucocorticoids to 11-dehydro metabolites.
244:
197:
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591:
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11-Deoxycorticosterone (desoxycortone, deoxycortone, desoxycorticosterone)
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558:"Progesterone: An enigmatic ligand for the mineralocorticoid receptor"
122:
1363:
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299:
231:
Aldosterone is produced in the zona glomerulosa of the cortex of the
209:
205:
166:
574:
3326:
11-Dehydrocorticosterone (11-oxocorticosterone, 17-deoxycortisone)
2005:
11-Dehydrocorticosterone (11-oxocorticosterone, 17-deoxycortisone)
1663:
1373:
868:
431:
395:
193:
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323:
181:, although a number of other endogenous hormones (including
3492:
Prednicarbate (prednisolone ethylcarbonate propionate)
773:
660:
Therapeutic
Advances in Endocrinology and Metabolism
3529:
3429:
Hydrocortamate (hydrocortisone diethylaminoacetate)
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32:
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615:"Diagram of the pathways of human steroidogenesis"
3502:Prednisolamate (prednisolone diethylaminoacetate)
2020:11β-Hydroxyprogesterone (21-deoxycorticosterone)
656:"Licorice abuse: Time to send a warning message"
447:An example of a synthetic mineralocorticoid is
2317:16β,17α-Epiestriol (16β-hydroxy-17α-estradiol)
3875:Mineralocorticoids and antimineralocorticoids
3570:17α-Hydroxyprogesterone (hydroxyprogesterone)
3279:
2919:
1792:
756:
235:and its secretion is mediated principally by
8:
771:Major chemical drug groups – based upon the
613:Häggström, Mikael; Richfield, David (2014).
358:11-beta hydroxysteroid dehydrogenase type II
3585:Canrenoate potassium (potassium canrenoate)
3424:Benzodrocortisone (hydrocortisone benzoate)
3350:11-Deoxycortisol (cortodoxone, cortexolone)
3048:Canrenoate potassium (potassium canrenoate)
3315:
3286:
3272:
3264:
2926:
2912:
2904:
2312:17α-Epiestriol (16α-hydroxy-17α-estradiol)
2068:
1889:
1799:
1785:
1777:
763:
749:
741:
733:at the U.S. National Library of Medicine
679:
630:
573:
536:Learn how and when to remove this message
398:due to excessive Na+ and water retention.
220:. This in turn results in an increase of
141:. Mineralocorticoids are produced in the
499:This article includes a list of general
265:
3372:16α,18-Dihydroxy-11-deoxycorticosterone
3248:Glucocorticoids and antiglucocorticoids
548:
200:in the principal cells of the cortical
145:and influence salt and water balances (
3550:7α-Thiomethylspironolactone (SC-26519)
3540:6β-Hydroxy-7α-thiomethylspironolactone
2101:Adrenosterone (11-ketoandrostenedione)
1750:Pharmacological classification systems
1117:Selective estrogen receptor modulators
337:without ligand binding interacts with
76:Corticosteroid; Mineralocorticosteroid
29:
3545:7α-Acetylthio-17α-hydroxyprogesterone
3243:Mineralocorticoid receptor modulators
2307:16β-Epiestriol (16β-hydroxyestradiol)
1397:Non-steroidal anti-inflammatory drugs
196:, as well as the active secretion of
7:
2960:Desoxycortone (desoxycorticosterone)
153:). The primary mineralocorticoid is
2477:Estradiol 3-glucuronide 17β-sulfate
1010:Angiotensin II receptor antagonists
387:. The two main resulting problems:
290:, and are able to freely cross the
189:) have mineralocorticoid function.
3880:Glucocorticoid receptor modulators
3311:Tooltip Mineralocorticoid receptor
505:it lacks sufficient corresponding
25:
3382:18-Hydroxy-11-deoxycorticosterone
2025:18-Hydroxy-11-deoxycorticosterone
1875:11β,17α,21-Trihydroxypregnenolone
329:The opposite mechanism is called
3595:Canrenone (canrenoate y-lactone)
3560:7α-Thiospironolactone (SC-24813)
3331:11-Dehydrocorticosterone acetate
1759:
1739:
1738:
490:
47:
3675:Oxprenoate potassium (RU-28318)
3453:Fludrocortisone (fludrocortone)
2226:Dihydrotestosterone glucuronide
1147:Hypothalamic–pituitary hormones
556:Baker ME, Katsu Y (July 2020).
282:Mineralocorticoids bind to the
212:in the lumenal membrane of the
137:, which in turn are a class of
3355:Cortifen (cortiphen, kortifen)
1902:3α,5α-Tetrahydrocorticosterone
418:congenital adrenal hyperplasia
1:
3870:Receptor/signaling modulators
3555:7α-Thioprogesterone (SC-8365)
2181:3α-Androstanediol glucuronide
899:Thrombolytics / fibrinolytics
424:) is often life-threatening.
3635:Hydroxyprogesterone caproate
1870:17α,21-Dihydroxypregnenolone
1610:Wakefulness-promoting agents
241:adrenocorticotrophic hormone
3695:Prorenoic acid (prorenoate)
3670:Oxprenoic acid (oxprenoate)
3660:Mexrenoic acid (mexrenoate)
3590:Canrenoic acid (canrenoate)
2246:Etiocholanolone glucuronide
2231:Dihydrotestosterone sulfate
3922:
3820:Miricorilant (CORT-118335)
3295:Mineralocorticoid receptor
2151:16α-Hydroxyandrostenedione
2096:11β-Hydroxyandrostenedione
2081:11-Ketodihydrotestosterone
1260:Intravenous immunoglobulin
294:of the cell. This type of
284:mineralocorticoid receptor
99:Mineralocorticoid receptor
3862:
3204:
3001:Methylprednisolone esters
2972:Hydrocortisone (cortisol)
2768:7β-Hydroxyepiandrosterone
2763:7α-Hydroxyepiandrosterone
2091:7β-Hydroxyepiandrosterone
1734:
584:10.1016/j.bcp.2020.113976
401:Accelerated excretion of
312:hormone response elements
310:, where it binds to many
121:
46:
37:
2653:5α-Dihydrocorticosterone
2594:Pregnanediol glucuronide
2256:Testosterone glucuronide
2216:Androsterone glucuronide
2161:16α-Hydroxy-DHEA sulfate
2030:18-Hydroxycorticosterone
1982:3α,5α-Tetrahydrocortisol
1907:5α-Dihydrocorticosterone
1315:Topoisomerase inhibitors
999:renin–angiotensin system
993:Calcium channel blockers
735:Medical Subject Headings
672:10.1177/2042018812454322
370:pseudohyperaldosteronism
204:and active secretion of
27:Group of corticosteroids
3885:List of corticosteroids
3580:18,19-Dinorprogesterone
3565:16α-Hydroxyprogesterone
3458:Fludrocortisone acetate
3407:Corticosterone benzoate
3367:11β-Hydroxyprogesterone
3253:List of corticosteroids
2989:Fludrocortisone acetate
2888:11β-Hydroxyprogesterone
2883:11α-Hydroxyprogesterone
2559:20β-Dihydroprogesterone
2554:20α-Dihydroprogesterone
2549:17α-Hydroxyprogesterone
2544:16α-Hydroxyprogesterone
2472:Estradiol 3-glucuronide
1957:17α-Hydroxyprogesterone
1952:17α-Hydroxypregnenolone
1860:17α-Hydroxypregnenolone
1855:11β-Hydroxypregnenolone
619:WikiJournal of Medicine
520:more precise citations.
476:List of corticosteroids
422:hemorrhagic adrenalitis
304:receptor-ligand complex
298:becomes activated upon
3715:SC-5233 (spirolactone)
3402:Corticosterone acetate
3377:17α-Hydroxyaldosterone
3037:Antimineralocorticoids
2939:antimineralocorticoids
2688:11-Deoxycorticosterone
2663:5β-Dihydroprogesterone
2658:5α-Dihydroprogesterone
2648:3β-Dihydroprogesterone
2643:3α-Dihydroprogesterone
2569:11-Deoxycorticosterone
2564:5α-Dihydroprogesterone
2211:Androstenediol sulfate
2191:5β-Dihydrotestosterone
2035:18-Hydroxyprogesterone
2015:11-Deoxycorticosterone
1912:11-Deoxycorticosterone
1865:21-Hydroxypregnenolone
1107:Hormonal contraception
1037:Bile acid sequestrants
818:Proton-pump inhibitors
781:gastrointestinal tract
456:antimineralocorticoids
444:
306:translocates into the
274:
3434:Hydrocortisone esters
2977:Hydrocortisone esters
2878:7α-Hydroxycholesterol
2858:Calcidiol/Calcifediol
2487:Estradiol 17β-sulfate
2467:Estradiol glucuronide
2387:27-Hydroxycholesterol
2000:5α-Dihydroaldosterone
1845:-Dihydroxycholesterol
632:10.15347/wjm/2014.005
435:
416:, although classical
318:region of the target
269:
177:mineralocorticoid is
3690:Prorenoate potassium
3655:Mexrenoate potassium
3343:Desoxycortone esters
2965:Desoxycortone esters
2853:7-Dehydrocholesterol
2713:Pregnenolone sulfate
2261:Testosterone sulfate
2221:Androsterone sulfate
1716:Radiopharmaceuticals
1504:Antiparkinson agents
3575:18-Deoxyaldosterone
3507:Prednisolone esters
3360:Cortodoxone acetate
3153:Synthesis modifiers
3013:Prednisolone esters
2893:Cholesterol sulfate
2628:-Hydroxycholesterol
2520:estradiol palmitate
2502:Estriol glucuronide
2492:Estrone glucuronide
2462:Estradiol disulfate
2136:Dihydrotestosterone
2121:Dehydroandrosterone
2086:11-Ketotestosterone
1922:11-Ketoprogesterone
1836:-Hydroxycholesterol
1499:Antimigraine agents
1489:Antidementia agents
1392:Anti-inflammatories
1082:Medicated dressings
1022:Antihyperlipidemics
849:Diabetes medication
345:of targeted genes.
339:heat shock proteins
187:deoxycorticosterone
3906:Mineralocorticoids
3470:Mometasone furoate
3387:19-Norprogesterone
3231:Never to phase III
2996:Methylprednisolone
2952:Mineralocorticoids
2935:Mineralocorticoids
2516:estradiol stearate
2512:Lipoidal estradiol
2442:2-Methoxyestradiol
2367:16β-Hydroxyestrone
2362:16α-Hydroxyestrone
2352:4-Methoxyestradiol
2337:4-Hydroxyestradiol
2322:2-Hydroxyestradiol
2251:Epietiocholanolone
2201:3β-Etiocholanediol
2196:3α-Etiocholanediol
1992:Mineralocorticoids
1977:5α-Dihydrocortisol
1352:Immunosuppressants
1222:Antimycobacterials
1178:Antithyroid agents
1162:Mineralocorticoids
966:Cardiac stimulants
956:Cardiac glycosides
948:cardiac therapy /
844:Anti-obesity drugs
731:Mineralocorticoids
445:
381:Hyperaldosteronism
278:Genomic mechanisms
275:
261:signaling cascades
214:intercalated cells
131:Mineralocorticoids
18:Mineralocorticoids
3893:
3892:
3858:
3857:
3519:Prednisone esters
3446:Cortisone acetate
3261:
3260:
3166:Aminoglutethimide
3025:Prednisone esters
2901:
2900:
2738:3α-Androstanediol
2607:
2606:
2482:Estradiol sulfate
2402:4-Androstenedione
2397:3β-Androstanediol
2392:3α-Androstanediol
2186:3β-Androstanediol
2176:3α-Androstanediol
2058:
2057:
1932:21-Deoxycortisone
1774:
1773:
1677:Ophthalmologicals
1387:Anabolic steroids
1290:Anticancer agents
1253:Ectoparasiticides
973:Antihypertensives
921:Antifibrinolytics
716:Dec;58(4):782-97.
562:Biochem Pharmacol
546:
545:
538:
443:mineralocorticoid
414:Addison's disease
410:Hypoaldosteronism
341:and prevents the
257:nuclear receptors
243:(ACTH) and local
218:collecting tubule
202:collecting tubule
128:
127:
94:Biological target
66:Class identifiers
60:mineralocorticoid
33:Mineralocorticoid
16:(Redirected from
3913:
3316:
3312:
3308:
3288:
3281:
3274:
3265:
2928:
2921:
2914:
2905:
2668:Allopregnanolone
2584:Allopregnanediol
2457:4-Methoxyestriol
2452:2-Methoxyestriol
2447:2-Methoxyestrone
2432:16α-Hydroxy-DHEA
2407:5-Androstenediol
2372:16-Ketoestradiol
2357:4-Methoxyestrone
2347:4-Hydroxyestrone
2342:4-Hydroxyestriol
2332:2-Hydroxyestrone
2327:2-Hydroxyestriol
2236:Etiocholanedione
2206:Androstanetriols
2156:16α-Hydroxy-DHEA
2069:
2010:11-Deoxycortisol
1927:21-Deoxycortisol
1917:11-Deoxycortisol
1890:
1801:
1794:
1787:
1778:
1763:
1742:
1741:
1726:Senotherapeutics
1580:Neuroprotectives
1575:Mood stabilizers
1474:Anti-ADHD agents
1414:Muscle relaxants
1347:Immunostimulants
1342:Immunomodulators
1174:Thyroid hormones
1112:Fertility agents
1015:Renin inhibitors
906:Antihemorrhagics
873:forming organs (
859:Dietary minerals
765:
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516:this article by
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348:Aldosterone and
335:hormone receptor
139:steroid hormones
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2984:Fludrocortisone
2946:
2932:
2902:
2897:
2868:Cholecalciferol
2835:
2816:Androstadienone
2788:Etiocholanolone
2758:7β-Hydroxy-DHEA
2753:7α-Hydroxy-DHEA
2698:Isopregnanolone
2693:Epipregnanolone
2603:
2525:
2507:Estriol sulfate
2497:Estrone sulfate
2427:7α-Hydroxy-DHEA
2265:
2241:Etiocholanolone
2146:Epitestosterone
2141:Epiandrosterone
2111:Androstenedione
2054:
1986:
1894:Glucocorticoids
1885:Corticosteroids
1879:
1813:
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1775:
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1766:Medicine portal
1730:
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1640:Bronchodilators
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1494:Antidepressants
1484:Anticonvulsants
1432:
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1419:Bisphosphonates
1409:Corticosteroids
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1305:Spindle poisons
1295:Antimetabolites
1278:
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1152:Corticosteroids
1133:
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1093:
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884:Antithrombotics
872:
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839:Antipropulsives
835:Antidiarrhoeals
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700:Further reading
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512:Please help to
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449:fludrocortisone
437:Fludrocortisone
430:
385:adrenal adenoma
378:
376:Pathophysiology
362:Protein:HSD11B2
331:transrepression
280:
271:Steroidogenesis
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135:corticosteroids
133:are a class of
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2828:
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2811:Androstadienol
2808:
2806:3β-Androstenol
2803:
2801:3α-Androstenol
2791:
2790:
2785:
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2775:
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2743:3α-Androstenol
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314:(HREs) in the
279:
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251:Mode of action
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222:blood pressure
173:. The primary
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2318:
2315:
2313:
2310:
2308:
2305:
2303:
2302:17α-Estradiol
2300:
2298:
2295:
2293:
2290:
2288:
2285:
2283:
2280:
2277:
2276:
2274:
2272:
2268:
2262:
2259:
2257:
2254:
2252:
2249:
2247:
2244:
2242:
2239:
2237:
2234:
2232:
2229:
2227:
2224:
2222:
2219:
2217:
2214:
2212:
2209:
2207:
2204:
2202:
2199:
2197:
2194:
2192:
2189:
2187:
2184:
2182:
2179:
2177:
2174:
2171:
2170:
2167:
2164:
2162:
2159:
2157:
2154:
2152:
2149:
2147:
2144:
2142:
2139:
2137:
2134:
2132:
2129:
2127:
2124:
2122:
2119:
2117:
2114:
2112:
2109:
2107:
2104:
2102:
2099:
2097:
2094:
2092:
2089:
2087:
2084:
2082:
2079:
2078:
2076:
2074:
2070:
2067:
2065:
2061:
2051:
2048:
2046:
2043:
2041:
2038:
2036:
2033:
2031:
2028:
2026:
2023:
2021:
2018:
2016:
2013:
2011:
2008:
2006:
2003:
2001:
1998:
1997:
1995:
1993:
1989:
1983:
1980:
1978:
1975:
1972:
1971:
1968:
1965:
1963:
1960:
1958:
1955:
1953:
1950:
1948:
1945:
1943:
1940:
1938:
1935:
1933:
1930:
1928:
1925:
1923:
1920:
1918:
1915:
1913:
1910:
1908:
1905:
1903:
1900:
1899:
1897:
1895:
1891:
1888:
1886:
1882:
1876:
1873:
1871:
1868:
1866:
1863:
1861:
1858:
1856:
1853:
1851:
1848:
1846:
1844:
1839:
1837:
1835:
1830:
1828:
1825:
1824:
1822:
1820:
1816:
1812:
1809:
1802:
1797:
1795:
1790:
1788:
1783:
1782:
1779:
1767:
1762:
1758:
1756:
1753:
1751:
1748:
1746:
1737:
1736:
1733:
1727:
1724:
1722:
1719:
1717:
1714:
1712:
1709:
1707:
1704:
1703:
1701:
1698:
1694:
1689:
1683:
1680:
1678:
1675:
1674:
1672:
1669:
1665:
1661:
1655:
1648:
1646:
1643:
1641:
1638:
1636:
1635:Decongestants
1633:
1632:
1630:
1627:
1623:
1617:
1611:
1608:
1606:
1603:
1601:
1598:
1596:
1593:
1591:
1588:
1586:
1583:
1581:
1578:
1576:
1573:
1571:
1567:
1564:
1560:
1557:
1555:
1554:Dissociatives
1552:
1550:
1547:
1546:
1545:
1544:Hallucinogens
1542:
1540:
1537:
1535:
1532:
1530:
1527:
1525:
1522:
1520:
1517:
1515:
1512:
1510:
1507:
1505:
1502:
1500:
1497:
1495:
1492:
1490:
1487:
1485:
1482:
1480:
1477:
1475:
1472:
1470:
1467:
1463:
1460:
1458:
1455:
1454:
1453:
1450:
1448:
1445:
1444:
1442:
1439:
1435:
1430:
1426:
1420:
1417:
1415:
1412:
1410:
1407:
1405:
1402:
1398:
1395:
1394:
1393:
1390:
1388:
1385:
1384:
1382:
1379:
1375:
1369:
1365:
1361:
1353:
1350:
1348:
1345:
1344:
1343:
1340:
1339:
1337:
1334:
1328:
1324:
1316:
1313:
1311:
1308:
1306:
1303:
1301:
1298:
1296:
1293:
1292:
1291:
1288:
1287:
1285:
1282:
1276:
1272:
1266:
1263:
1261:
1258:
1254:
1251:
1249:
1248:Anthelmintics
1246:
1244:
1241:
1240:
1239:
1236:
1234:
1231:
1229:
1226:
1223:
1219:
1215:
1212:
1211:
1209:
1206:
1202:
1198:
1194:
1189:
1185:
1179:
1175:
1172:
1170:
1167:
1163:
1160:
1158:
1155:
1154:
1153:
1150:
1148:
1145:
1144:
1142:
1139:
1135:
1129:
1123:
1120:
1118:
1115:
1113:
1110:
1108:
1105:
1104:
1102:
1099:
1095:
1092:genitourinary
1089:
1083:
1080:
1078:
1075:
1073:
1072:Antipruritics
1070:
1068:
1065:
1063:
1060:
1059:
1057:
1054:
1050:
1046:
1038:
1035:
1033:
1030:
1028:
1025:
1024:
1023:
1020:
1016:
1013:
1011:
1008:
1006:
1003:
1002:
1001:
1000:
996:
994:
991:
989:
988:Beta blockers
986:
984:
981:
979:
976:
974:
971:
967:
964:
962:
959:
957:
954:
953:
952:
951:
946:
945:
943:
940:
936:
930:
922:
919:
917:
914:
912:
909:
908:
907:
904:
900:
897:
895:
892:
890:
889:Antiplatelets
887:
886:
885:
882:
881:
879:
876:
870:
866:
860:
857:
855:
852:
850:
847:
845:
842:
840:
836:
833:
831:
828:
826:
823:
819:
816:
814:
807:
805:
802:
801:
800:
797:
796:
794:
791:
787:
782:
778:
774:
766:
761:
759:
754:
752:
747:
746:
743:
736:
732:
729:
728:
724:
718:
714:
711:
708:
705:
704:
699:
691:
687:
682:
677:
673:
669:
665:
661:
657:
650:
647:
642:
638:
633:
628:
624:
620:
616:
609:
606:
601:
597:
593:
589:
585:
581:
576:
571:
567:
563:
559:
552:
549:
540:
537:
529:
526:November 2013
519:
515:
509:
508:
502:
497:
488:
487:
481:
477:
474:
473:
469:
467:
465:
461:
457:
452:
450:
442:
438:
434:
427:
425:
423:
419:
415:
411:
404:
400:
397:
393:
390:
389:
388:
386:
382:
375:
373:
371:
367:
363:
359:
355:
351:
346:
344:
343:transcription
340:
336:
332:
327:
325:
321:
317:
313:
309:
305:
301:
297:
293:
292:lipid bilayer
289:
285:
277:
272:
268:
264:
262:
258:
250:
248:
246:
242:
238:
234:
233:adrenal gland
229:
227:
223:
219:
215:
211:
207:
203:
199:
195:
190:
188:
184:
180:
176:
172:
168:
160:
158:
156:
152:
151:fluid balance
148:
144:
140:
136:
132:
124:
120:
115:
112:
109:
107:
103:
100:
97:
95:
91:
88:
85:
83:
79:
75:
73:
69:
64:
59:
55:
50:
45:
42:
41:
36:
31:
19:
3835:Nitrendipine
3781:
3760:Trimegestone
3685:Progesterone
3680:Pregnenolone
3640:Medrogestone
3610:Drospirenone
3536:
3487:Prednazoline
3477:Prednisolone
3181:Ketoconazole
3143:Nitrendipine
3099:
3093:Trimegestone
3083:Progesterone
3078:Medrogestone
3058:Drospirenone
3044:
3008:Prednisolone
2951:
2934:
2874:
2846:
2826:Androsterone
2821:Androstenone
2794:
2783:DHEA sulfate
2773:Androsterone
2735:Androstanes:
2734:
2718:Progesterone
2708:Pregnenolone
2703:Pregnanolone
2639:
2625:
2621:Cholestanes:
2620:
2589:Pregnanediol
2581:Metabolites:
2580:
2539:Progesterone
2531:Progestogens
2439:Metabolites:
2438:
2417:DHEA sulfate
2383:
2278:
2173:Metabolites:
2172:
2166:Testosterone
2131:DHEA sulfate
2116:Androsterone
2064:Sex steroids
1991:
1974:Metabolites:
1973:
1967:Progesterone
1962:Pregnenolone
1850:Pregnenolone
1842:
1833:
1549:Psychedelics
1519:Aphrodisiacs
1193:infestations
1169:Sex hormones
1161:
1122:Sex hormones
1067:Cicatrizants
997:
983:Vasodilators
950:antianginals
947:
799:stomach acid
798:
663:
659:
649:
622:
618:
608:
565:
561:
551:
532:
523:
504:
453:
451:(Florinef).
446:
428:Pharmacology
408:
392:Hypertension
379:
354:glucosteroid
347:
328:
308:cell nucleus
286:in the cell
281:
254:
239:but also by
230:
226:blood volume
191:
183:progesterone
164:
149:balance and
130:
129:
117:Legal status
56:, the major
38:
3845:PF-03882845
3840:Ocedurenone
3805:Esaxerenone
3790:Apararenone
3750:Spiroxasone
3740:Spirorenone
3650:Metribolone
3645:Mespirenone
3530:Antagonists
3392:Aldosterone
3217:from market
3161:Acetoxolone
3118:Esaxerenone
3108:Apararenone
2748:7-Keto-DHEA
2633:Cholesterol
2422:7-Keto-DHEA
2040:Aldosterone
1827:Cholesterol
1682:Otologicals
1654:antagonists
1620:respiratory
1595:Orexigenics
1590:Neurotoxins
1539:Euphoriants
1529:Entactogens
1524:Depressants
1514:Anxiolytics
1452:Anesthetics
1228:Antifungals
825:Antiemetics
813:antagonists
518:introducing
208:via proton
179:aldosterone
155:aldosterone
147:electrolyte
123:In Wikidata
54:Aldosterone
3830:Nimodipine
3825:Nifedipine
3815:Finerenone
3810:Felodipine
3795:Benidipine
3785:Amlodipine
3765:Vamorolone
3705:RO-14-9012
3620:Eplerenone
3600:Dicirenone
3537:Steroidal:
3514:Prednisone
3482:Prednazate
3465:Mometasone
3298:modulators
3196:Trilostane
3186:Metyrapone
3138:Nimodipine
3133:Nifedipine
3128:Finerenone
3123:Felodipine
3113:Benidipine
3103:Amlodipine
3068:Eplerenone
3045:Steroidal:
3020:Prednisone
2863:Calcitriol
2796:Pheromones
2640:Pregnanes:
1819:Precursors
1808:Endogenous
1605:Stimulants
1585:Nootropics
1559:Deliriants
1534:Entheogens
1469:Anorectics
1447:Analgesics
1300:Alkylating
1233:Antivirals
1188:infections
1062:Emollients
916:Coagulants
786:metabolism
575:2001.07822
568:: 113976.
501:references
482:References
464:eplerenone
454:Important
175:endogenous
161:Physiology
58:endogenous
40:Drug class
3850:SM-368229
3700:Prorenone
3665:Mexrenone
3625:Gestodene
3441:Cortisone
3227:Phase III
3215:Withdrawn
3176:Enoxolone
3073:Gestodene
3053:Canrenone
2848:Vitamin D
2287:Estradiol
2279:Estranes:
2271:Estrogens
2073:Androgens
1947:Cortisone
1755:ATC codes
1721:Dressings
1706:Antidotes
1570:Sedatives
1566:Hypnotics
1275:malignant
1132:endocrine
978:Diuretics
911:Platelets
871:and blood
830:Laxatives
641:2002-4436
600:216028937
441:synthetic
245:potassium
198:potassium
3900:Category
3866:See also
3775:ZK-97894
3770:ZK-91587
3755:Tibolone
3735:SC-27169
3730:SC-19886
3710:RU-26752
3414:Cortisol
3319:Agonists
3239:See also
3191:Mitotane
2574:5α-DHDOC
2282:Estetrol
2050:Cortisol
1942:Cortisol
1811:steroids
1600:Serenics
1265:Vaccines
1032:Fibrates
854:Vitamins
804:Antacids
690:23185686
592:32305433
470:See also
366:Licorice
350:cortisol
316:promoter
296:receptor
247:levels.
111:Steroids
82:ATC code
72:Synonyms
3800:BR-4628
3720:SC-8109
2875:Others:
2514:(e.g.,
2384:Others:
2297:Estriol
2292:Estrone
1457:General
1364:muscles
1333:L03–L04
1329:disease
1281:L01–L02
1277:disease
1027:Statins
681:3498851
514:improve
322:in the
288:cytosol
216:of the
210:ATPases
206:protons
171:mineral
3210:WHO-EM
2840:Others
1841:20α,22
1764:
1743:
1691:other
1622:system
1374:joints
1327:immune
1134:system
1094:system
935:system
737:(MeSH)
688:
678:
639:
598:
590:
503:, but
333:. The
300:ligand
167:sodium
2728:THDOC
2683:DHDOC
1745:Drugs
1462:Local
1429:brain
1368:bones
869:blood
625:(1).
596:S2CID
570:arXiv
396:edema
320:genes
194:water
87:H02AA
2937:and
2778:DHEA
2412:DHEA
2126:DHEA
1372:and
1049:skin
686:PMID
637:ISSN
588:PMID
462:and
458:are
439:, a
394:and
224:and
185:and
169:, a
2943:H02
2723:THB
2678:DHC
1693:ATC
1431:and
1190:and
676:PMC
668:doi
627:doi
580:doi
566:177
352:(a
324:DNA
3902::
3420:)
3307:MR
3223::
2624:24
2518:,
1832:22
1568:/
1366:,
1216::
1205:QI
1203:,
1199:,
1176:/
837:/
784:/
684:.
674:.
662:.
658:.
635:.
621:.
617:.
594:.
586:.
578:.
564:.
560:.
466:.
372:.
326:.
263:.
228:.
157:.
3416:(
3287:e
3280:t
3273:v
2945:)
2941:(
2927:e
2920:t
2913:v
2850::
2798::
2626:S
2522:)
1843:R
1834:R
1800:e
1793:t
1786:v
1699:)
1697:V
1695:(
1670:)
1668:S
1666:(
1652:1
1650:H
1628:)
1626:R
1624:(
1440:)
1438:N
1436:(
1380:)
1378:M
1376:(
1370:,
1335:)
1331:(
1283:)
1279:(
1224:)
1220:(
1207:)
1201:P
1197:J
1195:(
1140:)
1138:H
1136:(
1100:)
1098:G
1096:(
1055:)
1053:D
1051:(
941:)
939:C
937:(
877:)
875:B
811:2
809:H
792:)
790:A
788:(
764:e
757:t
750:v
692:.
670::
664:3
643:.
629::
623:1
602:.
582::
572::
539:)
533:(
528:)
524:(
510:.
360:(
20:)
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
