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He is mentioned in documents for the first time in 1569, as having business relations with the communal director Isaac Rofe (Lékarz), subsequently his father-in-law. His first wife, Eva, who died before 1580, built with him the
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on 21 June 1689 and 16 May 1754. The only gifts dedicated by Meisel and his wife to this synagogue that have been preserved are a curtain (
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Meisel went on to build quarters and provide housing for Jews who migrated from what is now modern-day
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in Prague, which is still standing and serves today as the headquarters of the
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the enthusiasm with which the Jewish population received the gift.
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16th-century businesspeople from the Holy Roman Empire
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