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Nair, Jayaprakash K; Willoughby, Jennifer L. S; Chan, Amy; Charisse, Klaus; Alam, Md. Rowshon; Wang, Qianfan; Hoekstra, Menno; Kandasamy, Pachamuthu; Kel'In, Alexander V; Milstein, Stuart; Taneja, Nate; o'Shea, Jonathan; Shaikh, Sarfraz; Zhang, Ligang; Van Der Sluis, Ronald J; Jung, Michael E; Akinc,
605:
Donald M. Marcus; Elvin A. Kabat; Gerald
Schiffman (1964). "Immunochemical Studies on Blood Groups. XXXI. Destruction of Blood Group A Activity by an Enzyme from Clostridium tertium Which Deacetylates N-Acetylgalactosamine in Intact Blood Group Substances".
634:
Akin; Hutabarat, Renta; Kuchimanchi, Satya; Fitzgerald, Kevin; Zimmermann, Tracy; Van Berkel, Theo J. C; Maier, Martin A; Rajeev, Kallanthottathil G; Manoharan, Muthiah (2014).
461:
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636:"Multivalent N-Acetylgalactosamine-Conjugated siRNA Localizes in Hepatocytes and Elicits Robust RNAi-Mediated Gene Silencing"
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InChI=1S/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)/t4-,5-,6+,7-,8+/m1/s1
316:
InChI=1/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)/t4-,5-,6+,7-,8+/m1/s1
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538:, and is concentrated in sensory nerve structures of both humans and animals.
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Except where otherwise noted, data are given for materials in their
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In humans it is the terminal carbohydrate forming the antigen of
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172 to 173 °C (342 to 343 °F; 445 to 446 K)
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therapies targeted to the liver, where it binds to the
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It is typically the first monosaccharide that connects
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66:-Acetylchondrosamine; 2-Acetamido-2-deoxy-
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640:Journal of the American Chemical Society
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534:-Acetylgalactosamine is necessary for
309:Key: OVRNDRQMDRJTHS-CBQIKETKSA-N
143:
7:
541:GalNAc is also used as a targeting
319:Key: OVRNDRQMDRJTHS-CBQIKETKBW
219:
203:
14:
676:
446:
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521:in particular forms of protein
442:(at 25 °C , 100 kPa).
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361:
1:
555:asialoglycoprotein receptors
58:GalNAc; 2-Acetamido-2-deoxy-
536:intercellular communication
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547:antisense oligonucleotides
391:221.21 g/mol
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27:
46:2-(Acetylamino)-2-deoxy-
340:O(C(CO)O(O)1NC(C)=O)1O
683:N-Acetylgalactosamine
23:-Acetylgalactosamine
685:at Wikimedia Commons
484:-Acetylgalactosamine
646:(49): 16958–16961.
620:10.1021/bi00891a023
545:in investigational
24:
585:-Acetylglucosamine
469:Infobox references
423:-Acetylglucosamine
406:Related compounds
70:-galactopyranose;
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681:Media related to
652:10.1021/ja505986a
477:Chemical compound
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262:CompTox Dashboard
125:Interactive image
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16:Chemical compound
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571:Galactosamine
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84:Identifiers
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62:-galactose;
56:Other names
20:
704:Hexosamines
559:hepatocytes
508:blood group
492:amino sugar
349:Properties
145:CHEBI:40356
699:Acetamides
693:Categories
592:References
490:), is an
387:Molar mass
250:833755V695
156:ChemSpider
112:3D model (
91:CAS Number
50:-galactose
43:IUPAC name
576:Globoside
519:threonine
496:galactose
431:Galactose
101:1811-31-0
660:25434769
587:) GlcNAc
565:See also
502:Function
412:Related
176:DrugBank
74:-Acetyl-
462:what is
460: (
217:PubChem
185:DB03567
658:
543:ligand
515:serine
488:GalNAc
457:verify
454:
333:SMILES
205:C01074
37:Names
551:siRNA
298:InChI
230:84265
165:76020
136:ChEBI
114:JSmol
656:PMID
549:and
241:UNII
196:KEGG
648:doi
644:136
616:doi
561:.
557:on
517:or
510:A.
267:EPA
220:CID
695::
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371:15
662:.
650::
622:.
618::
612:3
583:N
580:(
532:N
524:O
486:(
482:N
452:N
421:N
380:6
377:O
374:N
368:H
365:8
362:C
269:)
265:(
116:)
76:D
72:N
68:D
64:N
60:D
48:D
21:N
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