244:
221:
118:
143:
495:
502:
250:
149:
1545:
1043:
are located in the amino-terminal of the protein and are responsible for NEDD1 localization in the centrosome, and the carboxy-terminal amino acids are needed for interactions with γ-tubulin. Depletion of NEDD1 causes impaired centrosome and chromatin
1498:
Takai S, Yoshida Y, Noda M, et al. (1995). "Assignment of the developmentally regulated gene NEDD1 to human chromosome 12q22 by fluorescence in situ hybridization".
257:
156:
1293:
Lüders J, Patel UK, Stearns T (2006). "GCP-WD is a gamma-tubulin targeting factor required for centrosomal and chromatin-mediated microtubule nucleation".
711:
730:
79:
1619:
1590:
1107:
1609:
1252:"NEDD1-dependent recruitment of the gamma-tubulin ring complex to the centrosome is necessary for centriole duplication and spindle assembly"
1125:
243:
1330:
Jung SY, Malovannaya A, Wei J, et al. (2005). "Proteomic analysis of steady-state nuclear hormone receptor coactivator complexes".
50:, GCP-WD, TUBGCP7, neural precursor cell expressed, developmentally down-regulated 1, NEDD1 gamma-tubulin ring complex targeting factor
954:
961:
220:
1143:
1094:
1073:
142:
117:
1090:
1069:
59:
1209:"Nek9 phosphorylation of NEDD1/GCP-WD contributes to Plk1 control of γ-tubulin recruitment to the mitotic centrosome"
256:
155:
1583:
249:
148:
775:
67:
1369:"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)"
1614:
756:
1164:"The role of NEDD1 phosphorylation by Aurora A in chromosomal microtubule nucleation and spindle function"
1576:
131:
1048:
assembly that results in the failure of microtubule nucleation and prevents proper spindle formation.
1458:
1220:
46:
912:
908:
904:
853:
849:
845:
494:
1523:
1355:
1318:
91:
1447:"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences"
937:
916:
878:
857:
501:
1515:
1486:
1433:
1398:
1347:
1310:
1281:
1238:
1195:
39:
1560:
1507:
1476:
1466:
1423:
1388:
1380:
1339:
1302:
1271:
1263:
1228:
1185:
1175:
336:
267:
211:
166:
87:
311:
1462:
1224:
1276:
1251:
1481:
1446:
1393:
1368:
1144:"Entrez Gene: NEDD1 neural precursor cell expressed, developmentally down-regulated 1"
645:
640:
635:
630:
625:
620:
604:
599:
594:
589:
584:
579:
574:
569:
564:
559:
543:
1603:
1556:
530:
1359:
1322:
1045:
329:
108:
1527:
1036:
71:
95:
1130:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1112:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1040:
412:
1233:
1208:
1180:
1163:
1028:
228:
125:
75:
1412:"Complete sequencing and characterization of 21,243 full-length human cDNAs"
675:
472:
350:
295:
282:
194:
181:
83:
1490:
1471:
1437:
1402:
1351:
1314:
1285:
1242:
1199:
1519:
1267:
1001:
996:
1343:
985:
820:
801:
1511:
1384:
1190:
1032:
787:
742:
969:
697:
1544:
1306:
1428:
1411:
1014:
Neural precursor cell expressed, developmentally down-regulated 1
660:
656:
510:
1552:
1021:
63:
1445:
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
319:
1564:
1367:
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
484:
930:
897:
871:
838:
646:
regulation of G2/M transition of mitotic cell cycle
1410:Ota T, Suzuki Y, Nishikawa T, et al. (2004).
1207:Sdelci S, Schütz M, Pinyol R, et al. (2012).
1086:
1084:
1082:
1065:
1063:
1061:
266:
165:
1250:Haren L, Remy MH, Bazin I, et al. (2006).
16:Protein-coding gene in the species Homo sapiens
1091:GRCm38: Ensembl release 89: ENSMUSG00000019988
1584:
8:
1070:GRCh38: Ensembl release 89: ENSG00000139350
1591:
1577:
671:
641:ciliary basal body-plasma membrane docking
526:
365:Skeletal muscle tissue of rectus abdominis
307:
206:
103:
1480:
1470:
1427:
1392:
1275:
1232:
1189:
1179:
393:Skeletal muscle tissue of biceps brachii
1162:Pinyol R, Scrofani J, Vernos I (2012).
1057:
20:
636:G2/M transition of mitotic cell cycle
271:
232:
227:
170:
129:
124:
7:
1541:
1539:
1563:. You can help Knowledge (XXG) by
927:
894:
868:
835:
811:
792:
766:
747:
721:
702:
626:protein localization to centrosome
489:
407:
345:
324:
14:
1543:
500:
493:
255:
248:
242:
219:
154:
147:
141:
116:
1024:and encodes the protein NEDD1.
1620:Human chromosome 12 gene stubs
511:More reference expression data
473:More reference expression data
1:
1035:through its interaction with
565:microtubule organizing center
240:
139:
1610:Genes on human chromosome 12
1451:Proc. Natl. Acad. Sci. U.S.A
1636:
1538:
1027:NEDD1 is localized in the
1234:10.1016/j.cub.2012.06.027
1181:10.1016/j.cub.2012.11.046
1126:"Mouse PubMed Reference:"
1108:"Human PubMed Reference:"
1000:
995:
991:
984:
968:
949:
934:
901:
890:
875:
842:
831:
818:
814:
799:
795:
786:
773:
769:
754:
750:
741:
728:
724:
709:
705:
696:
681:
674:
670:
654:
529:
525:
508:
492:
483:
470:
419:
410:
357:
348:
318:
310:
306:
289:
276:
239:
218:
209:
205:
188:
175:
138:
115:
106:
102:
57:
54:
44:
37:
32:
28:
23:
962:Chr 10: 92.52 – 92.56 Mb
955:Chr 12: 96.91 – 96.95 Mb
397:tibialis anterior muscle
1031:and it plays a role in
600:pericentriolar material
455:myocardium of ventricle
377:vastus lateralis muscle
1472:10.1073/pnas.242603899
459:triceps brachii muscle
1268:10.1083/jcb.200510028
234:Chromosome 10 (mouse)
132:Chromosome 12 (human)
1344:10.1210/me.2004-0476
1463:2002PNAS...9916899M
1225:2012CBio...22.1516S
590:apical part of cell
1551:This article on a
1512:10.1007/BF00225082
1385:10.1101/gr.2596504
776:ENSMUSG00000019988
614:Biological process
570:ciliary basal body
553:Cellular component
537:Molecular function
385:buccal mucosa cell
1572:
1571:
1457:(26): 16899–903.
1011:
1010:
1007:
1006:
980:
979:
945:
944:
924:
923:
886:
885:
865:
864:
827:
826:
808:
807:
782:
781:
763:
762:
737:
736:
718:
717:
666:
665:
521:
520:
517:
516:
479:
478:
466:
465:
404:
403:
302:
301:
201:
200:
96:NEDD1 - orthologs
1627:
1593:
1586:
1579:
1547:
1540:
1531:
1494:
1484:
1474:
1441:
1431:
1406:
1396:
1363:
1326:
1289:
1279:
1246:
1236:
1203:
1193:
1183:
1148:
1147:
1140:
1134:
1133:
1122:
1116:
1115:
1104:
1098:
1088:
1077:
1067:
1016:, also known as
993:
992:
964:
957:
940:
928:
919:
895:
891:RefSeq (protein)
881:
869:
860:
836:
812:
793:
767:
748:
722:
703:
672:
527:
513:
504:
497:
490:
475:
451:genital tubercle
447:digastric muscle
427:secondary oocyte
415:
413:Top expressed in
408:
389:ventricular zone
361:secondary oocyte
353:
351:Top expressed in
346:
325:
308:
298:
285:
274:
259:
252:
246:
235:
223:
207:
197:
184:
173:
158:
151:
145:
134:
120:
104:
98:
49:
42:
21:
1635:
1634:
1630:
1629:
1628:
1626:
1625:
1624:
1600:
1599:
1598:
1597:
1536:
1534:
1497:
1444:
1409:
1379:(10B): 2121–7.
1366:
1338:(10): 2451–65.
1332:Mol. Endocrinol
1329:
1307:10.1038/ncb1349
1292:
1249:
1219:(16): 1516–23.
1206:
1161:
1157:
1155:Further reading
1152:
1151:
1142:
1141:
1137:
1124:
1123:
1119:
1106:
1105:
1101:
1089:
1080:
1068:
1059:
1054:
1002:View/Edit Mouse
997:View/Edit Human
960:
953:
950:Location (UCSC)
936:
915:
911:
907:
903:
877:
856:
852:
848:
844:
757:ENSG00000139350
650:
609:
548:
544:protein binding
509:
499:
498:
471:
462:
457:
453:
449:
445:
443:cardiac muscles
441:
439:right ventricle
437:
433:
429:
425:
411:
400:
395:
391:
387:
383:
379:
375:
371:
367:
363:
349:
293:
280:
272:
262:
261:
260:
253:
233:
210:Gene location (
192:
179:
171:
161:
160:
159:
152:
130:
107:Gene location (
58:
45:
38:
17:
12:
11:
5:
1633:
1631:
1623:
1622:
1617:
1615:Human proteins
1612:
1602:
1601:
1596:
1595:
1588:
1581:
1573:
1570:
1569:
1548:
1533:
1532:
1495:
1442:
1429:10.1038/ng1285
1407:
1364:
1327:
1295:Nat. Cell Biol
1290:
1247:
1204:
1158:
1156:
1153:
1150:
1149:
1135:
1117:
1099:
1078:
1056:
1055:
1053:
1050:
1009:
1008:
1005:
1004:
999:
989:
988:
982:
981:
978:
977:
975:
973:
966:
965:
958:
951:
947:
946:
943:
942:
932:
931:
925:
922:
921:
899:
898:
892:
888:
887:
884:
883:
873:
872:
866:
863:
862:
840:
839:
833:
829:
828:
825:
824:
816:
815:
809:
806:
805:
797:
796:
790:
784:
783:
780:
779:
771:
770:
764:
761:
760:
752:
751:
745:
739:
738:
735:
734:
726:
725:
719:
716:
715:
707:
706:
700:
694:
693:
688:
683:
679:
678:
668:
667:
664:
663:
652:
651:
649:
648:
643:
638:
633:
628:
623:
617:
615:
611:
610:
608:
607:
602:
597:
592:
587:
582:
577:
572:
567:
562:
556:
554:
550:
549:
547:
546:
540:
538:
534:
533:
523:
522:
519:
518:
515:
514:
506:
505:
487:
481:
480:
477:
476:
468:
467:
464:
463:
461:
460:
456:
452:
448:
444:
440:
436:
432:
431:primary oocyte
428:
424:
420:
417:
416:
405:
402:
401:
399:
398:
394:
390:
386:
382:
381:deltoid muscle
378:
374:
370:
369:biceps brachii
366:
362:
358:
355:
354:
342:
341:
333:
322:
316:
315:
312:RNA expression
304:
303:
300:
299:
291:
287:
286:
278:
275:
270:
264:
263:
254:
247:
241:
237:
236:
231:
225:
224:
216:
215:
203:
202:
199:
198:
190:
186:
185:
177:
174:
169:
163:
162:
153:
146:
140:
136:
135:
128:
122:
121:
113:
112:
100:
99:
56:
52:
51:
43:
35:
34:
30:
29:
26:
25:
15:
13:
10:
9:
6:
4:
3:
2:
1632:
1621:
1618:
1616:
1613:
1611:
1608:
1607:
1605:
1594:
1589:
1587:
1582:
1580:
1575:
1574:
1568:
1566:
1562:
1558:
1557:chromosome 12
1554:
1549:
1546:
1542:
1537:
1529:
1525:
1521:
1517:
1513:
1509:
1505:
1501:
1496:
1492:
1488:
1483:
1478:
1473:
1468:
1464:
1460:
1456:
1452:
1448:
1443:
1439:
1435:
1430:
1425:
1421:
1417:
1413:
1408:
1404:
1400:
1395:
1390:
1386:
1382:
1378:
1374:
1370:
1365:
1361:
1357:
1353:
1349:
1345:
1341:
1337:
1333:
1328:
1324:
1320:
1316:
1312:
1308:
1304:
1301:(2): 137–47.
1300:
1296:
1291:
1287:
1283:
1278:
1273:
1269:
1265:
1262:(4): 505–15.
1261:
1257:
1253:
1248:
1244:
1240:
1235:
1230:
1226:
1222:
1218:
1214:
1210:
1205:
1201:
1197:
1192:
1187:
1182:
1177:
1173:
1169:
1165:
1160:
1159:
1154:
1145:
1139:
1136:
1131:
1127:
1121:
1118:
1113:
1109:
1103:
1100:
1096:
1092:
1087:
1085:
1083:
1079:
1075:
1071:
1066:
1064:
1062:
1058:
1051:
1049:
1047:
1042:
1038:
1034:
1030:
1025:
1023:
1020:, is a human
1019:
1015:
1003:
998:
994:
990:
987:
983:
976:
974:
971:
967:
963:
959:
956:
952:
948:
941:
939:
933:
929:
926:
920:
918:
914:
910:
906:
900:
896:
893:
889:
882:
880:
874:
870:
867:
861:
859:
855:
851:
847:
841:
837:
834:
832:RefSeq (mRNA)
830:
823:
822:
817:
813:
810:
804:
803:
798:
794:
791:
789:
785:
778:
777:
772:
768:
765:
759:
758:
753:
749:
746:
744:
740:
733:
732:
727:
723:
720:
714:
713:
708:
704:
701:
699:
695:
692:
689:
687:
684:
680:
677:
673:
669:
662:
658:
653:
647:
644:
642:
639:
637:
634:
632:
629:
627:
624:
622:
621:cell division
619:
618:
616:
613:
612:
606:
603:
601:
598:
596:
593:
591:
588:
586:
583:
581:
578:
576:
573:
571:
568:
566:
563:
561:
558:
557:
555:
552:
551:
545:
542:
541:
539:
536:
535:
532:
531:Gene ontology
528:
524:
512:
507:
503:
496:
491:
488:
486:
482:
474:
469:
458:
454:
450:
446:
442:
438:
434:
430:
426:
422:
421:
418:
414:
409:
406:
396:
392:
388:
384:
380:
376:
372:
368:
364:
360:
359:
356:
352:
347:
344:
343:
340:
338:
334:
332:
331:
327:
326:
323:
321:
317:
313:
309:
305:
297:
292:
288:
284:
279:
273:10|10 C2
269:
265:
258:
251:
245:
238:
230:
226:
222:
217:
213:
208:
204:
196:
191:
187:
183:
178:
168:
164:
157:
150:
144:
137:
133:
127:
123:
119:
114:
110:
105:
101:
97:
93:
89:
85:
81:
77:
73:
69:
65:
61:
53:
48:
41:
36:
31:
27:
22:
19:
1565:expanding it
1550:
1535:
1503:
1499:
1454:
1450:
1419:
1415:
1376:
1372:
1335:
1331:
1298:
1294:
1259:
1256:J. Cell Biol
1255:
1216:
1212:
1174:(2): 143–9.
1171:
1167:
1138:
1129:
1120:
1111:
1102:
1046:microtubules
1041:WD40 repeats
1026:
1017:
1013:
1012:
935:
913:NP_001128649
909:NP_001128648
905:NP_001128647
902:
876:
854:NM_001135177
850:NM_001135176
846:NM_001135175
843:
819:
800:
774:
755:
729:
710:
690:
685:
605:cytoskeleton
595:spindle pole
335:
328:
55:External IDs
18:
1506:(1): 96–8.
1422:(1): 40–5.
1191:10230/23504
294:92,558,282
281:92,520,608
193:96,953,780
180:96,907,224
33:Identifiers
1604:Categories
1500:Hum. Genet
1416:Nat. Genet
1373:Genome Res
1213:Curr. Biol
1168:Curr. Biol
1097:, May 2017
1076:, May 2017
1052:References
1029:centrosome
631:cell cycle
585:centrosome
339:(ortholog)
76:HomoloGene
1555:on human
1037:γ-tubulin
938:NP_032708
917:NP_690869
879:NM_008682
858:NM_152905
676:Orthologs
575:centriole
560:cytoplasm
84:GeneCards
1491:12477932
1438:14702039
1403:15489334
1360:24948585
1352:16051665
1323:27587898
1315:16378099
1286:16461362
1243:22818914
1200:23273898
1093:–
1072:–
986:Wikidata
655:Sources:
1520:7814034
1459:Bibcode
1277:2063671
1221:Bibcode
1095:Ensembl
1074:Ensembl
1033:mitosis
788:UniProt
743:Ensembl
682:Species
661:QuickGO
580:cytosol
314:pattern
172:12q23.1
40:Aliases
1528:902030
1526:
1518:
1489:
1482:139241
1479:
1436:
1401:
1394:528928
1391:
1358:
1350:
1321:
1313:
1284:
1274:
1241:
1198:
972:search
970:PubMed
821:P33215
802:Q8NHV4
712:121441
698:Entrez
485:BioGPS
435:atrium
423:zygote
64:600372
1559:is a
1524:S2CID
1356:S2CID
1319:S2CID
1018:Nedd1
731:17997
691:Mouse
686:Human
657:Amigo
373:sperm
337:Mouse
330:Human
277:Start
212:Mouse
176:Start
109:Human
88:NEDD1
72:97293
47:NEDD1
24:NEDD1
1561:stub
1553:gene
1516:PMID
1487:PMID
1434:PMID
1399:PMID
1348:PMID
1311:PMID
1282:PMID
1239:PMID
1196:PMID
1022:gene
320:Bgee
268:Band
229:Chr.
167:Band
126:Chr.
80:7439
60:OMIM
1508:doi
1477:PMC
1467:doi
1424:doi
1389:PMC
1381:doi
1340:doi
1303:doi
1272:PMC
1264:doi
1260:172
1229:doi
1186:hdl
1176:doi
290:End
189:End
92:OMA
68:MGI
1606::
1522:.
1514:.
1504:95
1502:.
1485:.
1475:.
1465:.
1455:99
1453:.
1449:.
1432:.
1420:36
1418:.
1414:.
1397:.
1387:.
1377:14
1375:.
1371:.
1354:.
1346:.
1336:19
1334:.
1317:.
1309:.
1297:.
1280:.
1270:.
1258:.
1254:.
1237:.
1227:.
1217:22
1215:.
1211:.
1194:.
1184:.
1172:23
1170:.
1166:.
1128:.
1110:.
1081:^
1060:^
1039:.
659:/
296:bp
283:bp
195:bp
182:bp
90:;
86::
82:;
78::
74:;
70::
66:;
62::
1592:e
1585:t
1578:v
1567:.
1530:.
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1493:.
1469::
1461::
1440:.
1426::
1405:.
1383::
1362:.
1342::
1325:.
1305::
1299:8
1288:.
1266::
1245:.
1231::
1223::
1202:.
1188::
1178::
1146:.
1132:.
1114:.
214:)
111:)
94::
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