Knowledge (XXG)

NFAM1

Source 📝

253: 230: 127: 152: 259: 158: 1316: 1181:"Calcineurin/nuclear factors of activated T cells (NFAT)-activating and immunoreceptor tyrosine-based activation motif (ITAM)-containing protein (CNAIP), a novel ITAM-containing protein that activates the calcineurin/NFAT-signaling pathway" 266: 165: 1052: 1296: 694: 713: 88: 1385: 1361: 1216:"Novel blocker of NFAT activation inhibits IL-6 production in human myometrial arteries and reduces vascular smooth muscle cell proliferation" 1118: 1380: 1136: 252: 961: 968: 229: 1214:
Nilsson LM, Sun ZW, Nilsson J, Nordström I, Chen YW, Molkentin JD, Wide-Swensson D, Hellstrand P, Lydrup ML, Gomez MF (March 2007).
1105: 1084: 151: 126: 1101: 1080: 68: 265: 164: 1354: 258: 157: 758: 76: 1044: 739: 1347: 140: 55: 940: 936: 932: 928: 907: 899: 869: 865: 861: 857: 836: 832: 100: 944: 903: 873: 828: 1281: 1238: 1202: 48: 1331: 1271: 1263: 1230: 1192: 345: 276: 220: 175: 1215: 96: 320: 1276: 1251: 628: 623: 618: 613: 608: 603: 598: 593: 588: 583: 567: 562: 557: 552: 536: 1374: 1327: 1300: 523: 80: 338: 117: 104: 1267: 1141:
National Center for Biotechnology Information, U.S. National Library of Medicine
1123:
National Center for Biotechnology Information, U.S. National Library of Medicine
1234: 421: 1039:
The protein encoded by this gene is a type I membrane receptor that activates
237: 134: 84: 1048: 658: 481: 359: 304: 291: 203: 190: 92: 17: 1285: 1252:"Nuclear factor of activated T-cells (NFAT) plays a role in SV40 infection" 1242: 1206: 1197: 1180: 1154: 1008: 1003: 1040: 992: 803: 784: 1056: 1024: 770: 725: 976: 680: 1315: 1055:(ITAM) and is thought to regulate the signaling and development of 643: 639: 1323: 1028: 594:
positive regulation of DNA-binding transcription factor activity
72: 1179:
Yang J, Hu G, Wang SW, Li Y, Martin R, Li K, Yao Z (May 2003).
59:, CNAIP, bK126B4.4, NFAT activating protein with ITAM motif 1 1155:"Entrez Gene: NFAT activating protein with ITAM motif 1" 584:
positive regulation of B cell receptor signaling pathway
328: 1335: 493: 921: 892: 850: 821: 1097: 1095: 1093: 1076: 1074: 1072: 275: 174: 27:Protein-coding gene in the species Homo sapiens 1102:GRCm38: Ensembl release 89: ENSMUSG00000058099 1053:Immunoreceptor tyrosine-based activation motif 1355: 1250:Manley K, O'Hara BA, Atwood WJ (March 2008). 8: 1081:GRCh38: Ensembl release 89: ENSG00000235568 1051:promoters. The encoded protein contains an 1362: 1348: 1297:United States National Library of Medicine 654: 619:positive regulation of cytokine production 519: 316: 215: 112: 1275: 1196: 1021:NFAT activating protein with ITAM motif 1 537:transmembrane signaling receptor activity 1295:This article incorporates text from the 1068: 1027:that in humans is encoded by the NFAM1 589:cell surface receptor signaling pathway 29: 280: 241: 236: 179: 138: 133: 7: 1312: 1310: 609:regulation of B cell differentiation 1334:. You can help Knowledge (XXG) by 918: 889: 847: 818: 794: 775: 749: 730: 704: 685: 498: 416: 354: 333: 25: 599:intracellular signal transduction 1314: 440:lumbar subsegment of spinal cord 264: 257: 251: 228: 163: 156: 150: 125: 1386:Human chromosome 22 gene stubs 553:integral component of membrane 482:More reference expression data 1: 1223:Am. J. Physiol., Cell Physiol 249: 148: 1381:Genes on human chromosome 22 1268:10.1016/j.virol.2007.10.029 1043:gene promoters such as the 1402: 1309: 1235:10.1152/ajpcell.00590.2005 568:azurophil granule membrane 1137:"Mouse PubMed Reference:" 1119:"Human PubMed Reference:" 1007: 1002: 998: 991: 975: 956: 925: 896: 885: 854: 825: 814: 801: 797: 782: 778: 769: 756: 752: 737: 733: 724: 711: 707: 692: 688: 679: 664: 657: 653: 637: 522: 518: 506: 501: 492: 479: 428: 419: 366: 357: 327: 319: 315: 298: 285: 248: 227: 218: 214: 197: 184: 147: 124: 115: 111: 66: 63: 53: 46: 41: 37: 32: 969:Chr 15: 82.88 – 82.92 Mb 962:Chr 22: 42.38 – 42.43 Mb 624:neutrophil degranulation 394:tendon of biceps brachii 1198:10.1074/jbc.M211060200 629:B cell differentiation 386:pancreatic ductal cell 604:inflammatory response 452:stroma of bone marrow 243:Chromosome 15 (mouse) 141:Chromosome 22 (human) 614:signal transduction 1322:This article on a 1299:, which is in the 759:ENSMUSG00000058099 577:Biological process 546:Cellular component 530:Molecular function 448:tibiofemoral joint 402:buccal mucosa cell 1343: 1342: 1191:(19): 16797–801. 1018: 1017: 1014: 1013: 987: 986: 952: 951: 915: 914: 881: 880: 844: 843: 810: 809: 791: 790: 765: 764: 746: 745: 720: 719: 701: 700: 649: 648: 514: 513: 510: 509: 488: 487: 475: 474: 413: 412: 390:bone marrow cells 311: 310: 210: 209: 105:NFAM1 - orthologs 16:(Redirected from 1393: 1364: 1357: 1350: 1318: 1311: 1289: 1279: 1246: 1220: 1210: 1200: 1165: 1164: 1162: 1161: 1151: 1145: 1144: 1133: 1127: 1126: 1115: 1109: 1099: 1088: 1078: 1000: 999: 971: 964: 947: 919: 910: 890: 886:RefSeq (protein) 876: 848: 839: 819: 795: 776: 750: 731: 705: 686: 655: 520: 499: 484: 468:genital tubercle 424: 422:Top expressed in 417: 362: 360:Top expressed in 355: 334: 317: 307: 294: 283: 268: 261: 255: 244: 232: 216: 206: 193: 182: 167: 160: 154: 143: 129: 113: 107: 58: 51: 30: 21: 1401: 1400: 1396: 1395: 1394: 1392: 1391: 1390: 1371: 1370: 1369: 1368: 1307: 1292: 1249: 1229:(3): C1167–78. 1218: 1213: 1178: 1174: 1172:Further reading 1169: 1168: 1159: 1157: 1153: 1152: 1148: 1135: 1134: 1130: 1117: 1116: 1112: 1100: 1091: 1079: 1070: 1065: 1037: 1009:View/Edit Mouse 1004:View/Edit Human 967: 960: 957:Location (UCSC) 943: 939: 935: 931: 927: 906: 902: 898: 872: 868: 864: 860: 856: 835: 831: 827: 740:ENSG00000235568 633: 572: 563:plasma membrane 541: 480: 471: 466: 462: 458: 454: 450: 446: 442: 438: 434: 420: 409: 404: 400: 396: 392: 388: 384: 380: 376: 372: 358: 302: 289: 281: 271: 270: 269: 262: 242: 219:Gene location ( 201: 188: 180: 170: 169: 168: 161: 139: 116:Gene location ( 67: 54: 47: 28: 23: 22: 15: 12: 11: 5: 1399: 1397: 1389: 1388: 1383: 1373: 1372: 1367: 1366: 1359: 1352: 1344: 1341: 1340: 1319: 1291: 1290: 1247: 1211: 1175: 1173: 1170: 1167: 1166: 1146: 1128: 1110: 1089: 1067: 1066: 1064: 1061: 1036: 1033: 1016: 1015: 1012: 1011: 1006: 996: 995: 989: 988: 985: 984: 982: 980: 973: 972: 965: 958: 954: 953: 950: 949: 923: 922: 916: 913: 912: 894: 893: 887: 883: 882: 879: 878: 852: 851: 845: 842: 841: 823: 822: 816: 812: 811: 808: 807: 799: 798: 792: 789: 788: 780: 779: 773: 767: 766: 763: 762: 754: 753: 747: 744: 743: 735: 734: 728: 722: 721: 718: 717: 709: 708: 702: 699: 698: 690: 689: 683: 677: 676: 671: 666: 662: 661: 651: 650: 647: 646: 635: 634: 632: 631: 626: 621: 616: 611: 606: 601: 596: 591: 586: 580: 578: 574: 573: 571: 570: 565: 560: 555: 549: 547: 543: 542: 540: 539: 533: 531: 527: 526: 516: 515: 512: 511: 508: 507: 504: 503: 496: 490: 489: 486: 485: 477: 476: 473: 472: 470: 469: 465: 461: 457: 453: 449: 445: 441: 437: 433: 429: 426: 425: 414: 411: 410: 408: 407: 403: 399: 395: 391: 387: 383: 379: 375: 371: 367: 364: 363: 351: 350: 342: 331: 325: 324: 321:RNA expression 313: 312: 309: 308: 300: 296: 295: 287: 284: 279: 273: 272: 263: 256: 250: 246: 245: 240: 234: 233: 225: 224: 212: 211: 208: 207: 199: 195: 194: 186: 183: 178: 172: 171: 162: 155: 149: 145: 144: 137: 131: 130: 122: 121: 109: 108: 65: 61: 60: 52: 44: 43: 39: 38: 35: 34: 26: 24: 14: 13: 10: 9: 6: 4: 3: 2: 1398: 1387: 1384: 1382: 1379: 1378: 1376: 1365: 1360: 1358: 1353: 1351: 1346: 1345: 1339: 1337: 1333: 1329: 1328:chromosome 22 1325: 1320: 1317: 1313: 1308: 1305: 1304: 1302: 1301:public domain 1298: 1287: 1283: 1278: 1273: 1269: 1265: 1261: 1257: 1253: 1248: 1244: 1240: 1236: 1232: 1228: 1224: 1217: 1212: 1208: 1204: 1199: 1194: 1190: 1186: 1185:J. Biol. Chem 1182: 1177: 1176: 1171: 1156: 1150: 1147: 1142: 1138: 1132: 1129: 1124: 1120: 1114: 1111: 1107: 1103: 1098: 1096: 1094: 1090: 1086: 1082: 1077: 1075: 1073: 1069: 1062: 1060: 1058: 1054: 1050: 1046: 1042: 1034: 1032: 1030: 1026: 1022: 1010: 1005: 1001: 997: 994: 990: 983: 981: 978: 974: 970: 966: 963: 959: 955: 948: 946: 942: 938: 934: 930: 924: 920: 917: 911: 909: 905: 901: 895: 891: 888: 884: 877: 875: 871: 867: 863: 859: 853: 849: 846: 840: 838: 834: 830: 824: 820: 817: 815:RefSeq (mRNA) 813: 806: 805: 800: 796: 793: 787: 786: 781: 777: 774: 772: 768: 761: 760: 755: 751: 748: 742: 741: 736: 732: 729: 727: 723: 716: 715: 710: 706: 703: 697: 696: 691: 687: 684: 682: 678: 675: 672: 670: 667: 663: 660: 656: 652: 645: 641: 636: 630: 627: 625: 622: 620: 617: 615: 612: 610: 607: 605: 602: 600: 597: 595: 592: 590: 587: 585: 582: 581: 579: 576: 575: 569: 566: 564: 561: 559: 556: 554: 551: 550: 548: 545: 544: 538: 535: 534: 532: 529: 528: 525: 524:Gene ontology 521: 517: 505: 500: 497: 495: 491: 483: 478: 467: 463: 459: 455: 451: 447: 443: 439: 435: 431: 430: 427: 423: 418: 415: 405: 401: 397: 393: 389: 385: 381: 377: 373: 369: 368: 365: 361: 356: 353: 352: 349: 347: 343: 341: 340: 336: 335: 332: 330: 326: 322: 318: 314: 306: 301: 297: 293: 288: 282:15|15 E1 278: 274: 267: 260: 254: 247: 239: 235: 231: 226: 222: 217: 213: 205: 200: 196: 192: 187: 177: 173: 166: 159: 153: 146: 142: 136: 132: 128: 123: 119: 114: 110: 106: 102: 98: 94: 90: 86: 82: 78: 74: 70: 62: 57: 50: 45: 40: 36: 31: 19: 1336:expanding it 1321: 1306: 1294: 1293: 1262:(1): 48–55. 1259: 1255: 1226: 1222: 1188: 1184: 1158:. Retrieved 1149: 1140: 1131: 1122: 1113: 1038: 1020: 1019: 941:NP_001258343 937:NP_001258342 933:NP_001258341 929:NP_001258340 926: 908:NP_001358291 900:NP_001305252 897: 870:NM_001271414 866:NM_001271413 862:NM_001271412 858:NM_001271411 855: 837:NM_001371362 833:NM_001318323 826: 802: 783: 757: 738: 712: 693: 673: 668: 344: 337: 64:External IDs 18:NFAM1 (gene) 436:bone marrow 432:granulocyte 382:skin of arm 378:granulocyte 303:82,917,507 290:82,877,174 202:42,432,403 189:42,380,407 42:Identifiers 1375:Categories 1160:2018-03-13 1108:, May 2017 1087:, May 2017 1063:References 348:(ortholog) 85:HomoloGene 1326:on human 1049:TNF-alpha 945:NP_083004 904:NP_666017 874:NM_028728 829:NM_145912 659:Orthologs 93:GeneCards 1286:18031784 1256:Virology 1243:17079331 1207:12615919 1104:– 1083:– 1041:cytokine 1035:Function 993:Wikidata 638:Sources: 558:membrane 460:habenula 406:appendix 370:monocyte 1277:2289909 1106:Ensembl 1085:Ensembl 1057:B-cells 1025:protein 771:UniProt 726:Ensembl 665:Species 644:QuickGO 323:pattern 181:22q13.2 81:1921289 49:Aliases 1284:  1274:  1241:  1205:  979:search 977:PubMed 804:Q8R4V1 785:Q8NET5 695:150372 681:Entrez 494:BioGPS 456:spleen 398:spleen 73:608740 1330:is a 1219:(PDF) 1045:IL-13 1023:is a 714:74039 674:Mouse 669:Human 640:Amigo 444:blood 374:blood 346:Mouse 339:Human 286:Start 221:Mouse 185:Start 118:Human 97:NFAM1 89:12528 56:NFAM1 33:NFAM1 1332:stub 1324:gene 1282:PMID 1239:PMID 1203:PMID 1059:. . 1047:and 1029:gene 329:Bgee 277:Band 238:Chr. 176:Band 135:Chr. 69:OMIM 1272:PMC 1264:doi 1260:372 1231:doi 1227:292 1193:doi 1189:278 502:n/a 464:lip 299:End 198:End 101:OMA 77:MGI 1377:: 1280:. 1270:. 1258:. 1254:. 1237:. 1225:. 1221:. 1201:. 1187:. 1183:. 1139:. 1121:. 1092:^ 1071:^ 1031:. 642:/ 305:bp 292:bp 204:bp 191:bp 99:; 95:: 91:; 87:: 83:; 79:: 75:; 71:: 1363:e 1356:t 1349:v 1338:. 1303:. 1288:. 1266:: 1245:. 1233:: 1209:. 1195:: 1163:. 1143:. 1125:. 223:) 120:) 103:: 20:)

Index

NFAM1 (gene)
Aliases
NFAM1
OMIM
608740
MGI
1921289
HomoloGene
12528
GeneCards
NFAM1
OMA
NFAM1 - orthologs
Human
Chromosome 22 (human)
Chr.
Chromosome 22 (human)
Chromosome 22 (human)
Genomic location for NFAM1
Genomic location for NFAM1
Band
bp
bp
Mouse
Chromosome 15 (mouse)
Chr.
Chromosome 15 (mouse)
Genomic location for NFAM1
Genomic location for NFAM1
Band

Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.