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Sodium-hydrogen exchange regulatory cofactor 2

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Lamprecht G, Heil A, Baisch S, et al. (2002). "The down regulated in adenoma (dra) gene product binds to the second PDZ domain of the NHE3 kinase A regulatory protein (E3KARP), potentially linking intestinal Cl-/HCO3- exchange to Na+/H+ exchange".
1456:, Choi Eui-Ju, Sun Kang Sang (October 2002). "The Na(+)/H(+) exchanger regulatory factor 2 mediates phosphorylation of serum- and glucocorticoid-induced protein kinase 1 by 3-phosphoinositide-dependent protein kinase 1". 2147:
Imai K, Sarker AH, Akiyama K, et al. (1999). "Genomic structure and sequence of a human homologue (NTHL1/NTH1) of Escherichia coli endonuclease III with those of the adjacent parts of TSC2 and SLC9A3R2 genes".
1378:"A C-terminal motif found in the beta2-adrenergic receptor, P2Y1 receptor and cystic fibrosis transmembrane conductance regulator determines binding to the Na+/H+ exchanger regulatory factor family of PDZ proteins" 2481:
Ingraffea J, Reczek D, Bretscher A (2002). "Distinct cell type-specific expression of scaffolding proteins EBP50 and E3KARP: EBP50 is generally expressed with ezrin in specific epithelia, whereas E3KARP is not".
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Li Y, Li Jian, Straight Samuel W, Kershaw David B (June 2002). "PDZ domain-mediated interaction of rabbit podocalyxin and Na(+)/H(+) exchange regulatory factor-2".
2783: 2179:"cAMP-induced phosphorylation and inhibition of Na(+)/H(+) exchanger 3 (NHE3) are dependent on the presence but not the phosphorylation of NHE regulatory factor" 1597:
Mahon MJ, Donowitz Mark, Yun C Chris, Segre Gino V (June 2002). "Na(+)/H(+ ) exchanger regulatory factor 2 directs parathyroid hormone 1 receptor signalling".
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Li Y, Li J, Straight SW, Kershaw DB (2002). "PDZ domain-mediated interaction of rabbit podocalyxin and Na(+)/H(+) exchange regulatory factor-2".
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Mahon MJ, Donowitz M, Yun CC, Segre GV (2002). "Na(+)/H(+ ) exchanger regulatory factor 2 directs parathyroid hormone 1 receptor signalling".
2513:"Ca(2+)-dependent inhibition of Na+/H+ exchanger 3 (NHE3) requires an NHE3-E3KARP-alpha-actinin-4 complex for oligomerization and endocytosis" 1550:"Ca(2+)-dependent inhibition of Na+/H+ exchanger 3 (NHE3) requires an NHE3-E3KARP-alpha-actinin-4 complex for oligomerization and endocytosis" 5914: 5640: 5166: 2748: 1317: 2249:"E3KARP mediates the association of ezrin and protein kinase A with the cystic fibrosis transmembrane conductance regulator in airway cells" 1915:"E3KARP mediates the association of ezrin and protein kinase A with the cystic fibrosis transmembrane conductance regulator in airway cells" 1299: 5498: 3366: 3035: 2802: 326: 4508: 4002: 2928: 2923: 2848: 2817: 1209: 2448:"Plasma membrane Ca2+ ATPase isoform 2b interacts preferentially with Na+/H+ exchanger regulatory factor 2 in apical plasma membranes" 1051: 303: 5894: 5795: 4962: 3924: 3222: 3136: 2893: 2327:"Identification of EPI64, a TBC/rabGAP domain-containing microvillar protein that binds to the first PDZ domain of EBP50 and E3KARP" 2114:"NHE3 kinase A regulatory protein E3KARP binds the epithelial brush border Na+/H+ exchanger NHE3 and the cytoskeletal protein ezrin" 1707:
Sitaraman SV, Wang Lixin, Wong Michelle, Bruewer Matthias, Hobert Michael, Yun C-H, Merlin Didier, Madara James L (September 2002).
1660:"NHE3 kinase A regulatory protein E3KARP binds the epithelial brush border Na+/H+ exchanger NHE3 and the cytoskeletal protein ezrin" 1044: 3726: 1435: 133:, E3KARP, NHE3RF2, NHERF-2, NHERF2, OCTS2, SIP-1, SIP1, TKA-1, Sodium-hydrogen exchange regulatory cofactor 2, SLC9A3 regulator 2 3987: 3063: 2908: 1286: 1265: 5835: 3462: 5919: 5815: 5810: 5781: 4322: 3886: 3688: 3683: 2810: 2622:"The adenosine 2b receptor is recruited to the plasma membrane and associates with E3KARP and Ezrin upon agonist stimulation" 1709:"The adenosine 2b receptor is recruited to the plasma membrane and associates with E3KARP and Ezrin upon agonist stimulation" 1205: 225: 200: 1282: 2018:"cAMP-mediated inhibition of the epithelial brush border Na+/H+ exchanger, NHE3, requires an associated regulatory protein" 65: 3881: 3876: 3871: 3856: 3851: 3846: 3841: 3631: 2071:"Identification of EBP50: A PDZ-containing phosphoprotein that associates with members of the ezrin-radixin-moesin family" 5207: 5009: 4809: 1261: 5805: 2777:: The crystal structure of the second PDZ domain of human NHERF-2 (SLC9A3R2) interacting with a mode 1 PDZ binding motif 339: 238: 142: 3797: 4777: 1193: 4656: 332: 231: 4360: 1758:"Gp135/podocalyxin and NHERF-2 participate in the formation of a preapical domain during polarization of MDCK cells" 5924: 4729: 3232: 2841: 5386: 5042: 3535: 5790: 3678: 2741: 5574: 5840: 3662: 3429: 1335:
Poulat F, de Santa Barbara P, Desclozeaux M, Soullier S, Moniot B, Bonneaud N, Boizet B, Berta P (March 1997).
841: 150: 5531: 4058: 5800: 5432: 3161: 2370:"Loss of glomerular foot processes is associated with uncoupling of podocalyxin from the actin cytoskeleton" 1815:"Loss of glomerular foot processes is associated with uncoupling of podocalyxin from the actin cytoskeleton" 822: 1337:"The human testis determining factor SRY binds a nuclear factor containing PDZ protein interaction domains" 2284:"TAZ: a novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins" 5776: 5612: 5298: 4483: 4408: 3802: 3673: 3668: 3242: 2844: 1237: 214: 5873: 5868: 3835: 3237: 2734: 2584: 2413:"Glucocorticoid activation of Na(+)/H(+) exchanger isoform 3 revisited. The roles of SGK1 and NHERF2" 2029: 1608: 1501:"Glucocorticoid activation of Na(+)/H(+) exchanger isoform 3 revisited. The roles of SGK1 and NHERF2" 1389: 129: 5465: 3171: 2946: 1027: 994: 990: 986: 982: 956: 923: 919: 915: 911: 577: 3227: 2608: 1640: 1436:"Entrez Gene: SLC9A3R2 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2" 174: 1023: 1019: 998: 952: 948: 927: 5368: 5363: 4711: 4706: 4633: 4628: 4623: 4618: 4613: 4608: 4588: 4583: 4578: 4573: 4558: 4548: 4538: 4533: 4523: 4498: 4304: 4289: 4284: 3906: 3901: 3896: 2693: 2673: 2643: 2600: 2563: 2534: 2499: 2469: 2434: 2399: 2356: 2313: 2270: 2235: 2200: 2165: 2135: 2100: 2057: 1993: 1985: 1944: 1936: 1895: 1887: 1852: 1834: 1795: 1777: 1738: 1730: 1689: 1681: 1632: 1624: 1579: 1571: 1530: 1522: 1481: 1473: 1417: 1376:
Hall RA, Ostedgaard LS, Premont RT, Blitzer JT, Rahman N, Welsh MJ, Lefkowitz RJ (July 1998).
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NHERF-2 is a scaffold protein that connects plasma membrane proteins with members of the
2588: 2033: 1612: 1393: 2351: 2326: 2214:"Regulation of phospholipase C-beta 3 activity by Na+/H+ exchanger regulatory factor 2" 2095: 2070: 1964:"Regulation of phospholipase C-beta 3 activity by Na+/H+ exchanger regulatory factor 2" 1790: 1757: 1453: 2394: 2369: 2308: 2283: 2161: 1847: 1814: 1469: 711: 695: 690: 685: 680: 675: 670: 665: 649: 644: 639: 634: 629: 624: 619: 5908: 5768: 2720: 2702: 2052: 2017: 1913:
Sun F, Hug M J, Lewarchik C M, Yun C H, Bradbury N A, Frizzell R A (September 2000).
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that plays a major role in transepithelial sodium absorption. SLC9A3R2, as well as
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This regulatory protein (factor) interacts with a sodium/hydrogen exchanger NHE3 (
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Hwang JI, Heo K, Shin K J, Kim E, Yun C, Ryu S H, Shin H S, Suh P G (June 2000).
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National Center for Biotechnology Information, U.S. National Library of Medicine
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National Center for Biotechnology Information, U.S. National Library of Medicine
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and to regulate their surface expression. It is necessary for cAMP-mediated
741: 555: 433: 378: 365: 277: 264: 166: 2792:: The crystal structure of the first PDZ domain of human NHERF-2 (SLC9A3R2) 2677: 2647: 2638: 2621: 2604: 2567: 2538: 2529: 2512: 2503: 2473: 2464: 2447: 2438: 2429: 2412: 2403: 2360: 2317: 2274: 2265: 2248: 2239: 2230: 2213: 2204: 2042: 1997: 1980: 1963: 1948: 1931: 1914: 1899: 1856: 1799: 1742: 1725: 1708: 1636: 1583: 1566: 1549: 1534: 1517: 1500: 1485: 2342: 2169: 2139: 2104: 2086: 2061: 1773: 1693: 1421: 1362: 1091: 1086: 5358: 5353: 5348: 5280: 4897: 4638: 4603: 4598: 4593: 4568: 4563: 4553: 4543: 4528: 4518: 4513: 4503: 4493: 4488: 4478: 4468: 4463: 4458: 4299: 4294: 4279: 4274: 4269: 4264: 4259: 4254: 4024: 3891: 3218: 1177: 1075: 886: 867: 2596: 1756:
Meder D, Shevchenko Anna, Simons Kai, FĂĽllekrug Joachim (January 2005).
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Kim JH, Lee-Kwon W, Park JB, Ryu SH, Yun CH, Donowitz M (June 2002).
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Sodium-hydrogen exchange regulatory cofactor 2 has been shown to
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System A & N, sodium-coupled neutral amino-acid transporter
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Takeda T, McQuistan T, Orlando R A, Farquhar M G (July 2001).
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Overview of all the structural information available in the
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high affinity glutamate and neutral amino-acid transporter
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Yun CH, Lamprecht G, Forster D V, Sidor A (October 1998).
1148:. In addition, it may also act as scaffold protein in the 2706:(Na(+)/H(+) exchange regulatory cofactor NHE-RF2) at the 2282:
Kanai F, Marignani PA, Sarbassova D, et al. (2001).
1122:(solute carrier family 9 isoform A3 regulatory factor 2) 3340:
cationic amino-acid transporter/glycoprotein-associated
402: 3365:
glycoprotein-associated/light or catalytic subunits of
2368:
Takeda T, McQuistan T, Orlando RA, Farquhar MG (2001).
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Zizak M, Lamprecht G, Steplock D, et al. (1999).
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phosphorylation, may play a role in NHE3 regulation.
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Na-independent, system-L like amino-acid transporter
1104:
Sodium-hydrogen exchange regulatory cofactor NHE-RF2
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Cystic fibrosis transmembrane conductance regulator
1012: 975: 941: 904: 2620:Sitaraman SV, Wang L, Wong M, et al. (2002). 1278: 1276: 1274: 1257: 1255: 1253: 2511:Kim JH, Lee-Kwon W, Park JB, et al. (2002). 2247:Sun F, Hug MJ, Lewarchik CM, et al. (2000). 2112:Yun CH, Lamprecht G, Forster DV, Sidor A (1998). 1499:Yun CC, Chen Yueping, Lang Florian (March 2002). 349: 248: 29:Protein-coding gene in the species Homo sapiens 2212:Hwang JI, Heo K, Shin KJ, et al. (2000). 1447: 1445: 1283:GRCm38: Ensembl release 89: ENSMUSG00000002504 2818: 2742: 1133:family and thereby helps to link them to the 8: 4205:organic cation/anion/zwitterion transporter 2446:DeMarco SJ, Chicka MC, Strehler EE (2002). 2016:Yun CH, Oh S, Zizak M, et al. (1997). 1262:GRCh38: Ensembl release 89: ENSG00000065054 5760: 5747: 5686: 5422: 5411: 4928: 4917: 4100: 4089: 3727:human Na-sulfate/carboxylate cotransporter 3621: 3610: 2883: 2872: 2868: 2857: 2825: 2811: 2803: 2749: 2735: 2727: 2717:United States National Library of Medicine 2069:Reczek D, Berryman M, Bretscher A (1998). 737: 602: 390: 289: 186: 76: 2637: 2528: 2463: 2428: 2393: 2350: 2307: 2264: 2229: 2194: 2129: 2094: 2051: 2041: 1979: 1930: 1846: 1789: 1724: 1675: 1565: 1516: 1411: 1401: 1352: 2715:This article incorporates text from the 4323:Na+-dependent ascorbic acid transporter 2764: 1249: 4111:Organic anion-transporting polypeptide 1164:) in the brush border membrane of the 31: 5167:proton-coupled amino-acid transporter 3367:heterodimeric amino-acid transporters 3036:heterodimeric amino-acid transporters 354: 315: 310: 253: 212: 207: 7: 3632:proton coupled metal ion transporter 5208:sugar-phosphate/phosphate exchanger 4810:facilitative nucleoside transporter 1210:Phosphoinositide-dependent kinase-1 1108:tyrosine kinase activator protein 1 712:protein-containing complex assembly 5010:type II Na-phosphate cotransporter 3223:sodium:neurotransmitter symporters 1452:Chun J, Kwon Taegun, Lee Eunjung, 1009: 972: 938: 901: 877: 858: 832: 813: 787: 768: 572: 490: 428: 407: 25: 4963:Vesicular glutamate transporter 1 3925:Vesicular glutamate transporter 1 3798:proton oligopeptide cotransporter 1118:that in humans is encoded by the 2782: 2767: 576: 338: 331: 325: 302: 237: 230: 224: 199: 40: 4778:Na-coupled nucleoside transport 4657:multifunctional anion exchanger 3988:vesicular monoamine transporter 2411:Yun CC, Chen Y, Lang F (2002). 1925:(38). UNITED STATES: 29539–46. 1719:(36). United States: 33188–95. 1670:(40). UNITED STATES: 25856–63. 1560:(26). United States: 23714–24. 2325:Reczek D, Bretscher A (2001). 1974:(22). UNITED STATES: 16632–7. 1878:(6). United States: F1129–39. 1511:(10). United States: 7676–83. 1206:Parathyroid hormone receptor 1 587:More reference expression data 556:More reference expression data 1: 5641:multidrug and toxin extrusion 4730:fatty acid transport proteins 2947:facilitative GLUT transporter 2548:Am. J. Physiol. Renal Physiol 2162:10.1016/S0378-1119(98)00485-5 1872:Am. J. Physiol. Renal Physiol 1825:(2). United States: 289–301. 1470:10.1016/S0006-291X(02)02428-2 1458:Biochem. Biophys. Res. Commun 323: 222: 5915:Genes on human chromosome 16 5387:basolateral iron transporter 5043:nucleoside-sugar transporter 3536:sodium bile salt cotransport 3137:sodium glucose cotransporter 2022:Proc. Natl. Acad. Sci. U.S.A 1768:(2). United States: 303–13. 1464:(2). United States: 207–15. 1382:Proc. Natl. Acad. Sci. U.S.A 2842:membrane transport proteins 2560:10.1152/ajprenal.00131.2001 1884:10.1152/ajprenal.00131.2001 460:right lobe of thyroid gland 5941: 5575:Putative sugar transporter 640:protein C-terminus binding 635:signaling receptor binding 620:molecular adaptor activity 472:left lobe of thyroid gland 5890: 5759: 5746: 5696: 5685: 5421: 5410: 4927: 4916: 4099: 4088: 3620: 3609: 2882: 2871: 2867: 2856: 2762: 1607:(6891). England: 858–61. 1318:"Mouse PubMed Reference:" 1300:"Human PubMed Reference:" 1112:SRY-interacting protein 1 1090: 1085: 1081: 1074: 1058: 1039: 1016: 979: 968: 945: 908: 897: 884: 880: 865: 861: 852: 839: 835: 820: 816: 807: 794: 790: 775: 771: 762: 747: 740: 736: 720: 605: 601: 584: 575: 566: 553: 502: 493: 440: 431: 401: 393: 389: 372: 359: 322: 301: 292: 288: 271: 258: 221: 198: 189: 185: 140: 137: 127: 120: 115: 84: 79: 62: 57: 52: 48: 39: 34: 5895:solute carrier disorders 5532:Choline-like transporter 3663:electroneutral cation-Cl 2300:10.1093/emboj/19.24.6778 2196:10.1074/jbc.274.35.24753 2131:10.1074/jbc.273.40.25856 1677:10.1074/jbc.273.40.25856 1106:(NHERF-2) also known as 1052:Chr 17: 24.86 – 24.87 Mb 5433:Magnesium transporter E 3064:bicarbonate transporter 2496:10.1078/0171-9335-00218 1403:10.1073/pnas.95.15.8496 1354:10.1074/jbc.272.11.7167 518:internal carotid artery 506:external carotid artery 456:upper lobe of left lung 5828:Antiporter (exchanger) 2639:10.1074/jbc.M202522200 2530:10.1074/jbc.M200835200 2465:10.1074/jbc.M111616200 2430:10.1074/jbc.M107768200 2266:10.1074/jbc.M004961200 2231:10.1074/jbc.M001410200 2043:10.1073/pnas.94.7.3010 1981:10.1074/jbc.M001410200 1932:10.1074/jbc.M004961200 1726:10.1074/jbc.M202522200 1567:10.1074/jbc.M200835200 1518:10.1074/jbc.M107768200 1045:Chr 16: 2.03 – 2.04 Mb 676:apical plasma membrane 5920:Solute carrier family 5299:metal ion transporter 4409:mitochondrial carrier 4059:type III Na-phosphate 2343:10.1083/jcb.153.1.191 2087:10.1083/jcb.139.1.169 1774:10.1083/jcb.200407072 1238:Solute carrier family 671:extracellular exosome 468:right coronary artery 317:Chromosome 17 (mouse) 215:Chromosome 16 (human) 1131:ezrin/moesin/radixin 630:beta-catenin binding 480:left coronary artery 179:SLC9A3R2 - orthologs 80:List of PDB id codes 53:Available structures 5466:Ammonia transporter 4361:Na/(Ca-K) exchanger 2597:10.1038/nature00816 2589:2002Natur.417..858M 2034:1997PNAS...94.3010Y 1621:10.1038/nature00816 1613:2002Natur.417..858M 1394:1998PNAS...95.8496H 686:endomembrane system 625:phosphatase binding 452:right lobe of liver 5613:Folate transporter 3034:heavy subunits of 2719:, which is in the 1144:and inhibition of 842:ENSMUSG00000002504 705:Biological process 659:Cellular component 613:Molecular function 5925:Membrane proteins 5902: 5901: 5886: 5885: 5882: 5881: 5742: 5741: 5738: 5737: 5734: 5733: 5681: 5680: 5677: 5676: 5406: 5405: 5402: 5401: 4912: 4911: 4908: 4907: 4084: 4083: 4080: 4079: 3605: 3604: 3601: 3600: 2834:Membrane proteins 2800: 2799: 2670:10.1021/bi0259103 2484:Eur. J. Cell Biol 1101: 1100: 1097: 1096: 1070: 1069: 1035: 1034: 1006: 1005: 964: 963: 935: 934: 893: 892: 874: 873: 848: 847: 829: 828: 803: 802: 784: 783: 732: 731: 597: 596: 593: 592: 562: 561: 549: 548: 487: 486: 476:left uterine tube 385: 384: 284: 283: 111: 110: 107: 106: 63:Ortholog search: 16:(Redirected from 5932: 5861: 5860: 5859: 5761: 5748: 5687: 5669:Heme transporter 5423: 5412: 4929: 4918: 4101: 4090: 3770:urea transporter 3622: 3611: 2884: 2873: 2869: 2858: 2838:carrier proteins 2827: 2820: 2813: 2804: 2786: 2771: 2751: 2744: 2737: 2728: 2681: 2664:(41): 12336–42. 2651: 2641: 2632:(36): 33188–95. 2616: 2583:(6891): 858–61. 2571: 2542: 2532: 2523:(26): 23714–24. 2507: 2477: 2467: 2458:(12): 10506–11. 2442: 2432: 2407: 2397: 2386:10.1172/JCI12539 2364: 2354: 2321: 2311: 2278: 2268: 2259:(38): 29539–46. 2243: 2233: 2208: 2198: 2173: 2143: 2133: 2124:(40): 25856–63. 2108: 2098: 2065: 2055: 2045: 2002: 2001: 1983: 1959: 1953: 1952: 1934: 1910: 1904: 1903: 1867: 1861: 1860: 1850: 1831:10.1172/JCI12539 1810: 1804: 1803: 1793: 1753: 1747: 1746: 1728: 1704: 1698: 1697: 1679: 1655: 1649: 1648: 1594: 1588: 1587: 1569: 1545: 1539: 1538: 1520: 1496: 1490: 1489: 1449: 1440: 1439: 1432: 1426: 1425: 1415: 1405: 1388:(15): 8496–501. 1373: 1367: 1366: 1356: 1332: 1326: 1325: 1314: 1308: 1307: 1296: 1290: 1280: 1269: 1259: 1182:protein kinase A 1083: 1082: 1054: 1047: 1030: 1010: 1001: 973: 969:RefSeq (protein) 959: 939: 930: 902: 878: 859: 833: 814: 788: 769: 738: 650:cadherin binding 603: 589: 580: 573: 558: 498: 496:Top expressed in 491: 436: 434:Top expressed in 429: 408: 391: 381: 368: 357: 342: 335: 329: 318: 306: 290: 280: 267: 256: 241: 234: 228: 217: 203: 187: 181: 132: 125: 102: 77: 71: 50: 49: 44: 32: 21: 5940: 5939: 5935: 5934: 5933: 5931: 5930: 5929: 5905: 5904: 5903: 5898: 5878: 5858: 5855: 5854: 5853: 5851: 5822: 5785: 5755: 5730: 5692: 5673: 5657: 5629: 5601: 5563: 5520: 5487: 5454: 5417: 5398: 5375: 5287: 5234: 5196: 5155: 5031: 4998: 4974: 4951: 4923: 4904: 4836: 4798: 4766: 4718: 4645: 4397: 4349: 4311: 4193: 4095: 4076: 4047: 4009: 3976: 3913: 3836:monocarboxylate 3824: 3786: 3758: 3715: 3651: 3616: 3597: 3524: 3451: 3430:Na/Ca exchanger 3418: 3329: 3203: 3125: 3052: 3023: 2935: 2878: 2863: 2852: 2831: 2801: 2796: 2793: 2787: 2778: 2772: 2758: 2755: 2689: 2684: 2654: 2619: 2574: 2554:(6): F1129–39. 2545: 2510: 2480: 2445: 2423:(10): 7676–83. 2410: 2374:J. Clin. Invest 2367: 2324: 2294:(24): 6778–91. 2281: 2246: 2224:(22): 16632–7. 2211: 2189:(35): 24753–8. 2176: 2146: 2111: 2068: 2015: 2011: 2009:Further reading 2006: 2005: 1961: 1960: 1956: 1912: 1911: 1907: 1869: 1868: 1864: 1819:J. Clin. Invest 1812: 1811: 1807: 1755: 1754: 1750: 1706: 1705: 1701: 1657: 1656: 1652: 1596: 1595: 1591: 1547: 1546: 1542: 1498: 1497: 1493: 1451: 1450: 1443: 1434: 1433: 1429: 1375: 1374: 1370: 1347:(11): 7167–72. 1334: 1333: 1329: 1316: 1315: 1311: 1298: 1297: 1293: 1281: 1272: 1260: 1251: 1246: 1234: 1202:Actinin alpha 4 1190: 1170:small intestine 1166:proximal tubule 1158: 1142:phosphorylation 1092:View/Edit Mouse 1087:View/Edit Human 1050: 1043: 1040:Location (UCSC) 1026: 1022: 1018: 997: 993: 989: 985: 981: 955: 951: 947: 926: 922: 918: 914: 910: 823:ENSG00000065054 716: 700: 666:plasma membrane 654: 645:protein binding 585: 554: 545: 542:right ventricle 540: 536: 532: 530:right lung lobe 528: 524: 522:ascending aorta 520: 516: 512: 508: 494: 483: 478: 474: 470: 466: 462: 458: 454: 450: 446: 432: 376: 363: 356:17|17 A3.3 355: 345: 344: 343: 336: 316: 293:Gene location ( 275: 262: 254: 244: 243: 242: 235: 213: 190:Gene location ( 141: 128: 121: 86: 64: 30: 23: 22: 15: 12: 11: 5: 5938: 5936: 5928: 5927: 5922: 5917: 5907: 5906: 5900: 5899: 5891: 5888: 5887: 5884: 5883: 5880: 5879: 5877: 5876: 5871: 5866: 5865: 5864: 5856: 5838: 5832: 5830: 5824: 5823: 5821: 5820: 5819: 5818: 5813: 5803: 5798: 5793: 5788: 5783: 5779: 5773: 5771: 5757: 5756: 5751: 5744: 5743: 5740: 5739: 5736: 5735: 5732: 5731: 5729: 5728: 5723: 5718: 5713: 5708: 5703: 5697: 5694: 5693: 5690: 5683: 5682: 5679: 5678: 5675: 5674: 5672: 5671: 5665: 5663: 5659: 5658: 5656: 5655: 5654: 5653: 5648: 5637: 5635: 5631: 5630: 5628: 5627: 5626: 5625: 5620: 5609: 5607: 5603: 5602: 5600: 5599: 5598: 5597: 5592: 5587: 5582: 5571: 5569: 5565: 5564: 5562: 5561: 5560: 5559: 5554: 5549: 5544: 5539: 5528: 5526: 5522: 5521: 5519: 5518: 5517: 5516: 5511: 5506: 5495: 5493: 5489: 5488: 5486: 5485: 5484: 5483: 5478: 5473: 5462: 5460: 5456: 5455: 5453: 5452: 5451: 5450: 5445: 5440: 5429: 5427: 5419: 5418: 5415: 5408: 5407: 5404: 5403: 5400: 5399: 5397: 5396: 5395: 5394: 5383: 5381: 5377: 5376: 5374: 5373: 5372: 5371: 5366: 5361: 5356: 5351: 5346: 5341: 5336: 5331: 5326: 5321: 5316: 5311: 5306: 5295: 5293: 5289: 5288: 5286: 5285: 5284: 5283: 5278: 5273: 5268: 5263: 5258: 5253: 5242: 5240: 5236: 5235: 5233: 5232: 5231: 5230: 5225: 5220: 5215: 5204: 5202: 5198: 5197: 5195: 5194: 5193: 5192: 5184: 5179: 5174: 5163: 5161: 5157: 5156: 5154: 5153: 5152: 5151: 5146: 5141: 5136: 5129: 5128: 5127: 5122: 5117: 5110: 5109: 5108: 5103: 5096: 5095: 5094: 5089: 5084: 5079: 5072: 5071: 5070: 5065: 5060: 5055: 5050: 5039: 5037: 5033: 5032: 5030: 5029: 5028: 5027: 5022: 5017: 5006: 5004: 5000: 4999: 4997: 4996: 4995: 4994: 4982: 4980: 4976: 4975: 4973: 4972: 4971: 4970: 4959: 4957: 4953: 4952: 4950: 4949: 4948: 4947: 4935: 4933: 4925: 4924: 4921: 4914: 4913: 4910: 4909: 4906: 4905: 4903: 4902: 4901: 4900: 4895: 4890: 4885: 4880: 4875: 4870: 4865: 4860: 4855: 4844: 4842: 4838: 4837: 4835: 4834: 4833: 4832: 4827: 4822: 4817: 4806: 4804: 4800: 4799: 4797: 4796: 4795: 4794: 4789: 4774: 4772: 4768: 4767: 4765: 4764: 4763: 4762: 4757: 4752: 4747: 4742: 4737: 4726: 4724: 4720: 4719: 4717: 4716: 4715: 4714: 4709: 4704: 4699: 4694: 4689: 4684: 4679: 4674: 4669: 4664: 4653: 4651: 4647: 4646: 4644: 4643: 4642: 4641: 4636: 4631: 4626: 4621: 4616: 4611: 4606: 4601: 4596: 4591: 4586: 4581: 4576: 4571: 4566: 4561: 4556: 4551: 4546: 4541: 4536: 4531: 4526: 4521: 4516: 4511: 4506: 4501: 4496: 4491: 4486: 4481: 4476: 4471: 4466: 4461: 4456: 4451: 4446: 4441: 4436: 4431: 4426: 4421: 4416: 4405: 4403: 4399: 4398: 4396: 4395: 4394: 4393: 4388: 4383: 4378: 4373: 4368: 4357: 4355: 4351: 4350: 4348: 4347: 4346: 4345: 4340: 4335: 4330: 4319: 4317: 4313: 4312: 4310: 4309: 4308: 4307: 4302: 4297: 4292: 4287: 4282: 4277: 4272: 4267: 4262: 4257: 4252: 4247: 4242: 4237: 4232: 4227: 4222: 4217: 4212: 4201: 4199: 4195: 4194: 4192: 4191: 4190: 4189: 4177: 4176: 4175: 4170: 4163: 4162: 4161: 4154: 4153: 4152: 4147: 4140: 4139: 4138: 4133: 4128: 4123: 4118: 4107: 4105: 4097: 4096: 4093: 4086: 4085: 4082: 4081: 4078: 4077: 4075: 4074: 4073: 4072: 4067: 4061:cotransporter 4055: 4053: 4049: 4048: 4046: 4045: 4044: 4043: 4038: 4033: 4017: 4015: 4011: 4010: 4008: 4007: 4006: 4005: 4000: 3995: 3984: 3982: 3978: 3977: 3975: 3974: 3973: 3972: 3967: 3962: 3957: 3952: 3947: 3942: 3937: 3932: 3921: 3919: 3915: 3914: 3912: 3911: 3910: 3909: 3904: 3899: 3894: 3889: 3884: 3879: 3874: 3869: 3864: 3859: 3854: 3849: 3844: 3832: 3830: 3826: 3825: 3823: 3822: 3821: 3820: 3815: 3810: 3805: 3794: 3792: 3788: 3787: 3785: 3784: 3783: 3782: 3777: 3766: 3764: 3760: 3759: 3757: 3756: 3755: 3754: 3749: 3744: 3739: 3734: 3723: 3721: 3717: 3716: 3714: 3713: 3712: 3711: 3706: 3701: 3696: 3691: 3686: 3681: 3676: 3671: 3665:cotransporter 3659: 3657: 3653: 3652: 3650: 3649: 3648: 3647: 3639: 3628: 3626: 3618: 3617: 3614: 3607: 3606: 3603: 3602: 3599: 3598: 3596: 3595: 3590: 3585: 3580: 3575: 3574: 3573: 3568: 3563: 3558: 3553: 3548: 3543: 3532: 3530: 3526: 3525: 3523: 3522: 3521: 3520: 3515: 3510: 3505: 3500: 3495: 3490: 3485: 3480: 3475: 3470: 3463:Na/H exchanger 3459: 3457: 3453: 3452: 3450: 3449: 3448: 3447: 3442: 3437: 3426: 3424: 3420: 3419: 3417: 3416: 3415: 3414: 3409: 3404: 3399: 3394: 3389: 3384: 3379: 3374: 3363: 3362: 3361: 3356: 3351: 3346: 3337: 3335: 3331: 3330: 3328: 3327: 3326: 3325: 3320: 3315: 3310: 3305: 3300: 3295: 3290: 3285: 3280: 3275: 3270: 3265: 3260: 3255: 3250: 3245: 3240: 3235: 3230: 3211: 3209: 3205: 3204: 3202: 3201: 3200: 3199: 3194: 3189: 3184: 3179: 3174: 3169: 3164: 3159: 3154: 3149: 3144: 3133: 3131: 3127: 3126: 3124: 3123: 3122: 3121: 3116: 3111: 3106: 3101: 3096: 3091: 3086: 3081: 3076: 3071: 3060: 3058: 3054: 3053: 3051: 3050: 3049: 3048: 3043: 3031: 3029: 3025: 3024: 3022: 3021: 3020: 3019: 3014: 3009: 3004: 2999: 2994: 2989: 2984: 2979: 2974: 2969: 2964: 2959: 2954: 2943: 2941: 2937: 2936: 2934: 2933: 2932: 2931: 2926: 2921: 2916: 2911: 2906: 2901: 2890: 2888: 2880: 2879: 2876: 2865: 2864: 2861: 2854: 2853: 2845:solute carrier 2832: 2830: 2829: 2822: 2815: 2807: 2798: 2797: 2795: 2794: 2788: 2781: 2779: 2773: 2766: 2763: 2760: 2759: 2756: 2754: 2753: 2746: 2739: 2731: 2712: 2711: 2688: 2687:External links 2685: 2683: 2682: 2652: 2617: 2572: 2543: 2508: 2478: 2443: 2408: 2380:(2): 289–301. 2365: 2337:(1): 191–206. 2322: 2279: 2244: 2209: 2174: 2144: 2109: 2066: 2012: 2010: 2007: 2004: 2003: 1954: 1905: 1862: 1805: 1748: 1699: 1650: 1589: 1540: 1491: 1454:Suh Pann-Ghill 1441: 1427: 1368: 1327: 1309: 1291: 1270: 1248: 1247: 1245: 1242: 1241: 1240: 1233: 1230: 1189: 1186: 1157: 1154: 1099: 1098: 1095: 1094: 1089: 1079: 1078: 1072: 1071: 1068: 1067: 1065: 1063: 1056: 1055: 1048: 1041: 1037: 1036: 1033: 1032: 1014: 1013: 1007: 1004: 1003: 977: 976: 970: 966: 965: 962: 961: 943: 942: 936: 933: 932: 906: 905: 899: 895: 894: 891: 890: 882: 881: 875: 872: 871: 863: 862: 856: 850: 849: 846: 845: 837: 836: 830: 827: 826: 818: 817: 811: 805: 804: 801: 800: 792: 791: 785: 782: 781: 773: 772: 766: 760: 759: 754: 749: 745: 744: 734: 733: 730: 729: 718: 717: 715: 714: 708: 706: 702: 701: 699: 698: 696:focal adhesion 693: 688: 683: 678: 673: 668: 662: 660: 656: 655: 653: 652: 647: 642: 637: 632: 627: 622: 616: 614: 610: 609: 599: 598: 595: 594: 591: 590: 582: 581: 570: 564: 563: 560: 559: 551: 550: 547: 546: 544: 543: 539: 535: 531: 527: 523: 519: 515: 511: 507: 503: 500: 499: 488: 485: 484: 482: 481: 477: 473: 469: 465: 461: 457: 453: 449: 445: 441: 438: 437: 425: 424: 416: 405: 399: 398: 395:RNA expression 387: 386: 383: 382: 374: 370: 369: 361: 358: 353: 347: 346: 337: 330: 324: 320: 319: 314: 308: 307: 299: 298: 286: 285: 282: 281: 273: 269: 268: 260: 257: 252: 246: 245: 236: 229: 223: 219: 218: 211: 205: 204: 196: 195: 183: 182: 139: 135: 134: 126: 118: 117: 113: 112: 109: 108: 105: 104: 82: 81: 73: 72: 61: 55: 54: 46: 45: 37: 36: 28: 24: 14: 13: 10: 9: 6: 4: 3: 2: 5937: 5926: 5923: 5921: 5918: 5916: 5913: 5912: 5910: 5897: 5896: 5889: 5875: 5872: 5870: 5867: 5863: 5847: 5844: 5843: 5842: 5839: 5837: 5834: 5833: 5831: 5829: 5825: 5817: 5814: 5812: 5809: 5808: 5807: 5804: 5802: 5799: 5797: 5794: 5792: 5789: 5787: 5780: 5778: 5775: 5774: 5772: 5770: 5769:Cotransporter 5766: 5762: 5758: 5754: 5749: 5745: 5727: 5724: 5722: 5719: 5717: 5714: 5712: 5709: 5707: 5704: 5702: 5699: 5698: 5695: 5688: 5684: 5670: 5667: 5666: 5664: 5660: 5652: 5649: 5647: 5644: 5643: 5642: 5639: 5638: 5636: 5632: 5624: 5621: 5619: 5616: 5615: 5614: 5611: 5610: 5608: 5604: 5596: 5593: 5591: 5588: 5586: 5583: 5581: 5578: 5577: 5576: 5573: 5572: 5570: 5566: 5558: 5555: 5553: 5550: 5548: 5545: 5543: 5540: 5538: 5535: 5534: 5533: 5530: 5529: 5527: 5523: 5515: 5512: 5510: 5507: 5505: 5502: 5501: 5500: 5497: 5496: 5494: 5490: 5482: 5479: 5477: 5474: 5472: 5469: 5468: 5467: 5464: 5463: 5461: 5457: 5449: 5446: 5444: 5441: 5439: 5436: 5435: 5434: 5431: 5430: 5428: 5424: 5420: 5413: 5409: 5393: 5390: 5389: 5388: 5385: 5384: 5382: 5378: 5370: 5367: 5365: 5362: 5360: 5357: 5355: 5352: 5350: 5347: 5345: 5342: 5340: 5337: 5335: 5332: 5330: 5327: 5325: 5322: 5320: 5317: 5315: 5312: 5310: 5307: 5305: 5302: 5301: 5300: 5297: 5296: 5294: 5290: 5282: 5279: 5277: 5274: 5272: 5269: 5267: 5264: 5262: 5259: 5257: 5254: 5252: 5249: 5248: 5247: 5244: 5243: 5241: 5237: 5229: 5226: 5224: 5221: 5219: 5216: 5214: 5211: 5210: 5209: 5206: 5205: 5203: 5199: 5191: 5188: 5185: 5183: 5180: 5178: 5175: 5173: 5170: 5169: 5168: 5165: 5164: 5162: 5158: 5150: 5147: 5145: 5142: 5140: 5137: 5135: 5132: 5131: 5130: 5126: 5123: 5121: 5118: 5116: 5113: 5112: 5111: 5107: 5104: 5102: 5099: 5098: 5097: 5093: 5090: 5088: 5085: 5083: 5080: 5078: 5075: 5074: 5073: 5069: 5066: 5064: 5061: 5059: 5056: 5054: 5051: 5049: 5046: 5045: 5044: 5041: 5040: 5038: 5034: 5026: 5023: 5021: 5018: 5016: 5013: 5012: 5011: 5008: 5007: 5005: 5001: 4993: 4990: 4989: 4987: 4984: 4983: 4981: 4977: 4969: 4966: 4965: 4964: 4961: 4960: 4958: 4954: 4946: 4943: 4942: 4940: 4937: 4936: 4934: 4930: 4926: 4919: 4915: 4899: 4896: 4894: 4891: 4889: 4886: 4884: 4881: 4879: 4876: 4874: 4871: 4869: 4866: 4864: 4861: 4859: 4856: 4854: 4851: 4850: 4849: 4846: 4845: 4843: 4839: 4831: 4828: 4826: 4823: 4821: 4818: 4816: 4813: 4812: 4811: 4808: 4807: 4805: 4801: 4793: 4790: 4788: 4785: 4784: 4783: 4779: 4776: 4775: 4773: 4769: 4761: 4758: 4756: 4753: 4751: 4748: 4746: 4743: 4741: 4738: 4736: 4733: 4732: 4731: 4728: 4727: 4725: 4721: 4713: 4710: 4708: 4705: 4703: 4700: 4698: 4695: 4693: 4690: 4688: 4685: 4683: 4680: 4678: 4675: 4673: 4670: 4668: 4665: 4663: 4660: 4659: 4658: 4655: 4654: 4652: 4648: 4640: 4637: 4635: 4632: 4630: 4627: 4625: 4622: 4620: 4617: 4615: 4612: 4610: 4607: 4605: 4602: 4600: 4597: 4595: 4592: 4590: 4587: 4585: 4582: 4580: 4577: 4575: 4572: 4570: 4567: 4565: 4562: 4560: 4557: 4555: 4552: 4550: 4547: 4545: 4542: 4540: 4537: 4535: 4532: 4530: 4527: 4525: 4522: 4520: 4517: 4515: 4512: 4510: 4507: 4505: 4502: 4500: 4497: 4495: 4492: 4490: 4487: 4485: 4482: 4480: 4477: 4475: 4472: 4470: 4467: 4465: 4462: 4460: 4457: 4455: 4452: 4450: 4447: 4445: 4442: 4440: 4437: 4435: 4432: 4430: 4427: 4425: 4422: 4420: 4417: 4415: 4412: 4411: 4410: 4407: 4406: 4404: 4400: 4392: 4389: 4387: 4384: 4382: 4379: 4377: 4374: 4372: 4369: 4367: 4364: 4363: 4362: 4359: 4358: 4356: 4352: 4344: 4341: 4339: 4336: 4334: 4331: 4329: 4326: 4325: 4324: 4321: 4320: 4318: 4314: 4306: 4303: 4301: 4298: 4296: 4293: 4291: 4288: 4286: 4283: 4281: 4278: 4276: 4273: 4271: 4268: 4266: 4263: 4261: 4258: 4256: 4253: 4251: 4248: 4246: 4243: 4241: 4238: 4236: 4233: 4231: 4228: 4226: 4223: 4221: 4218: 4216: 4213: 4211: 4208: 4207: 4206: 4203: 4202: 4200: 4196: 4187: 4183: 4180: 4179: 4178: 4174: 4171: 4169: 4166: 4165: 4164: 4160: 4157: 4156: 4155: 4151: 4148: 4146: 4143: 4142: 4141: 4137: 4134: 4132: 4129: 4127: 4124: 4122: 4119: 4117: 4114: 4113: 4112: 4109: 4108: 4106: 4102: 4098: 4091: 4087: 4071: 4068: 4066: 4063: 4062: 4060: 4057: 4056: 4054: 4050: 4042: 4039: 4037: 4034: 4032: 4029: 4028: 4026: 4022: 4019: 4018: 4016: 4012: 4004: 4001: 3999: 3996: 3994: 3991: 3990: 3989: 3986: 3985: 3983: 3979: 3971: 3968: 3966: 3963: 3961: 3958: 3956: 3953: 3951: 3948: 3946: 3943: 3941: 3938: 3936: 3933: 3931: 3928: 3927: 3926: 3923: 3922: 3920: 3916: 3908: 3905: 3903: 3900: 3898: 3895: 3893: 3890: 3888: 3885: 3883: 3880: 3878: 3875: 3873: 3870: 3868: 3865: 3863: 3860: 3858: 3855: 3853: 3850: 3848: 3845: 3843: 3840: 3839: 3837: 3834: 3833: 3831: 3827: 3819: 3816: 3814: 3811: 3809: 3806: 3804: 3801: 3800: 3799: 3796: 3795: 3793: 3789: 3781: 3778: 3776: 3773: 3772: 3771: 3768: 3767: 3765: 3761: 3753: 3750: 3748: 3745: 3743: 3740: 3738: 3735: 3733: 3730: 3729: 3728: 3725: 3724: 3722: 3718: 3710: 3707: 3705: 3702: 3700: 3697: 3695: 3692: 3690: 3687: 3685: 3682: 3680: 3677: 3675: 3672: 3670: 3667: 3666: 3664: 3661: 3660: 3658: 3654: 3646: 3643: 3640: 3638: 3635: 3634: 3633: 3630: 3629: 3627: 3623: 3619: 3612: 3608: 3594: 3591: 3589: 3586: 3584: 3581: 3579: 3576: 3572: 3569: 3567: 3564: 3562: 3559: 3557: 3554: 3552: 3549: 3547: 3544: 3542: 3539: 3538: 3537: 3534: 3533: 3531: 3527: 3519: 3516: 3514: 3511: 3509: 3506: 3504: 3501: 3499: 3496: 3494: 3491: 3489: 3486: 3484: 3481: 3479: 3476: 3474: 3471: 3469: 3466: 3465: 3464: 3461: 3460: 3458: 3454: 3446: 3443: 3441: 3438: 3436: 3433: 3432: 3431: 3428: 3427: 3425: 3421: 3413: 3410: 3408: 3405: 3403: 3400: 3398: 3395: 3393: 3390: 3388: 3385: 3383: 3380: 3378: 3375: 3373: 3370: 3369: 3368: 3364: 3360: 3357: 3355: 3352: 3350: 3347: 3345: 3342: 3341: 3339: 3338: 3336: 3332: 3324: 3321: 3319: 3316: 3314: 3311: 3309: 3306: 3304: 3301: 3299: 3296: 3294: 3291: 3289: 3286: 3284: 3281: 3279: 3276: 3274: 3271: 3269: 3266: 3264: 3261: 3259: 3256: 3254: 3251: 3249: 3246: 3244: 3241: 3239: 3236: 3234: 3231: 3229: 3226: 3225: 3224: 3220: 3216: 3213: 3212: 3210: 3206: 3198: 3195: 3193: 3190: 3188: 3185: 3183: 3180: 3178: 3175: 3173: 3170: 3168: 3165: 3163: 3160: 3158: 3155: 3153: 3150: 3148: 3145: 3143: 3140: 3139: 3138: 3135: 3134: 3132: 3128: 3120: 3117: 3115: 3112: 3110: 3107: 3105: 3102: 3100: 3097: 3095: 3092: 3090: 3087: 3085: 3082: 3080: 3077: 3075: 3072: 3070: 3067: 3066: 3065: 3062: 3061: 3059: 3055: 3047: 3044: 3042: 3039: 3038: 3037: 3033: 3032: 3030: 3026: 3018: 3015: 3013: 3010: 3008: 3005: 3003: 3000: 2998: 2995: 2993: 2990: 2988: 2985: 2983: 2980: 2978: 2975: 2973: 2970: 2968: 2965: 2963: 2960: 2958: 2955: 2953: 2950: 2949: 2948: 2945: 2944: 2942: 2938: 2930: 2927: 2925: 2922: 2920: 2917: 2915: 2912: 2910: 2907: 2905: 2902: 2900: 2897: 2896: 2895: 2892: 2891: 2889: 2885: 2881: 2874: 2870: 2866: 2859: 2855: 2850: 2846: 2843: 2839: 2835: 2828: 2823: 2821: 2816: 2814: 2809: 2808: 2805: 2791: 2785: 2780: 2776: 2770: 2765: 2761: 2752: 2747: 2745: 2740: 2738: 2733: 2732: 2729: 2725: 2724: 2722: 2721:public domain 2718: 2709: 2705: 2704: 2699: 2695: 2691: 2690: 2686: 2679: 2675: 2671: 2667: 2663: 2659: 2653: 2649: 2645: 2640: 2635: 2631: 2627: 2626:J. Biol. Chem 2623: 2618: 2614: 2610: 2606: 2602: 2598: 2594: 2590: 2586: 2582: 2578: 2573: 2569: 2565: 2561: 2557: 2553: 2549: 2544: 2540: 2536: 2531: 2526: 2522: 2518: 2517:J. Biol. Chem 2514: 2509: 2505: 2501: 2497: 2493: 2489: 2485: 2479: 2475: 2471: 2466: 2461: 2457: 2453: 2452:J. Biol. Chem 2449: 2444: 2440: 2436: 2431: 2426: 2422: 2418: 2417:J. Biol. Chem 2414: 2409: 2405: 2401: 2396: 2391: 2387: 2383: 2379: 2375: 2371: 2366: 2362: 2358: 2353: 2348: 2344: 2340: 2336: 2332: 2328: 2323: 2319: 2315: 2310: 2305: 2301: 2297: 2293: 2289: 2285: 2280: 2276: 2272: 2267: 2262: 2258: 2254: 2253:J. Biol. Chem 2250: 2245: 2241: 2237: 2232: 2227: 2223: 2219: 2218:J. Biol. Chem 2215: 2210: 2206: 2202: 2197: 2192: 2188: 2184: 2183:J. Biol. Chem 2180: 2175: 2171: 2167: 2163: 2159: 2156:(2): 287–95. 2155: 2151: 2145: 2141: 2137: 2132: 2127: 2123: 2119: 2118:J. Biol. Chem 2115: 2110: 2106: 2102: 2097: 2092: 2088: 2084: 2081:(1): 169–79. 2080: 2076: 2072: 2067: 2063: 2059: 2054: 2049: 2044: 2039: 2035: 2031: 2028:(7): 3010–5. 2027: 2023: 2019: 2014: 2013: 2008: 1999: 1995: 1991: 1987: 1982: 1977: 1973: 1969: 1968:J. Biol. Chem 1965: 1958: 1955: 1950: 1946: 1942: 1938: 1933: 1928: 1924: 1920: 1919:J. Biol. Chem 1916: 1909: 1906: 1901: 1897: 1893: 1889: 1885: 1881: 1877: 1873: 1866: 1863: 1858: 1854: 1849: 1844: 1840: 1836: 1832: 1828: 1824: 1820: 1816: 1809: 1806: 1801: 1797: 1792: 1787: 1783: 1779: 1775: 1771: 1767: 1763: 1759: 1752: 1749: 1744: 1740: 1736: 1732: 1727: 1722: 1718: 1714: 1713:J. Biol. Chem 1710: 1703: 1700: 1695: 1691: 1687: 1683: 1678: 1673: 1669: 1665: 1664:J. Biol. Chem 1661: 1654: 1651: 1646: 1642: 1638: 1634: 1630: 1626: 1622: 1618: 1614: 1610: 1606: 1602: 1601: 1593: 1590: 1585: 1581: 1577: 1573: 1568: 1563: 1559: 1555: 1554:J. Biol. Chem 1551: 1544: 1541: 1536: 1532: 1528: 1524: 1519: 1514: 1510: 1506: 1505:J. Biol. Chem 1502: 1495: 1492: 1487: 1483: 1479: 1475: 1471: 1467: 1463: 1459: 1455: 1448: 1446: 1442: 1437: 1431: 1428: 1423: 1419: 1414: 1409: 1404: 1399: 1395: 1391: 1387: 1383: 1379: 1372: 1369: 1364: 1360: 1355: 1350: 1346: 1342: 1341:J. Biol. Chem 1338: 1331: 1328: 1323: 1319: 1313: 1310: 1305: 1301: 1295: 1292: 1288: 1284: 1279: 1277: 1275: 1271: 1267: 1263: 1258: 1256: 1254: 1250: 1243: 1239: 1236: 1235: 1231: 1229: 1227: 1223: 1219: 1215: 1211: 1207: 1203: 1199: 1195: 1187: 1185: 1183: 1179: 1175: 1171: 1167: 1163: 1155: 1153: 1151: 1147: 1143: 1139: 1136: 1132: 1127: 1125: 1121: 1117: 1114:(SIP-1) is a 1113: 1109: 1105: 1093: 1088: 1084: 1080: 1077: 1073: 1066: 1064: 1061: 1057: 1053: 1049: 1046: 1042: 1038: 1031: 1029: 1025: 1021: 1015: 1011: 1008: 1002: 1000: 996: 992: 988: 984: 978: 974: 971: 967: 960: 958: 954: 950: 944: 940: 937: 931: 929: 925: 921: 917: 913: 907: 903: 900: 898:RefSeq (mRNA) 896: 889: 888: 883: 879: 876: 870: 869: 864: 860: 857: 855: 851: 844: 843: 838: 834: 831: 825: 824: 819: 815: 812: 810: 806: 799: 798: 793: 789: 786: 780: 779: 774: 770: 767: 765: 761: 758: 755: 753: 750: 746: 743: 739: 735: 728: 724: 719: 713: 710: 709: 707: 704: 703: 697: 694: 692: 689: 687: 684: 682: 679: 677: 674: 672: 669: 667: 664: 663: 661: 658: 657: 651: 648: 646: 643: 641: 638: 636: 633: 631: 628: 626: 623: 621: 618: 617: 615: 612: 611: 608: 607:Gene ontology 604: 600: 588: 583: 579: 574: 571: 569: 565: 557: 552: 541: 537: 533: 529: 525: 521: 517: 513: 509: 505: 504: 501: 497: 492: 489: 479: 475: 471: 467: 464:right auricle 463: 459: 455: 451: 447: 444:apex of heart 443: 442: 439: 435: 430: 427: 426: 423: 421: 417: 415: 414: 410: 409: 406: 404: 400: 396: 392: 388: 380: 375: 371: 367: 362: 352: 348: 341: 334: 328: 321: 313: 309: 305: 300: 296: 291: 287: 279: 274: 270: 266: 261: 251: 247: 240: 233: 227: 220: 216: 210: 206: 202: 197: 193: 188: 184: 180: 176: 172: 168: 164: 160: 156: 152: 148: 144: 136: 131: 124: 119: 114: 103: 101: 97: 93: 89: 83: 78: 75: 74: 70: 67: 60: 56: 51: 47: 43: 38: 33: 27: 19: 5892: 4988:transporter 4941:transporter 4027:transporter 3838:transporter 3221:- dependent 2789: 2774: 2714: 2713: 2701: 2661: 2658:Biochemistry 2657: 2629: 2625: 2580: 2576: 2551: 2547: 2520: 2516: 2487: 2483: 2455: 2451: 2420: 2416: 2377: 2373: 2334: 2331:J. Cell Biol 2330: 2291: 2287: 2256: 2252: 2221: 2217: 2186: 2182: 2153: 2149: 2121: 2117: 2078: 2075:J. Cell Biol 2074: 2025: 2021: 1971: 1967: 1957: 1922: 1918: 1908: 1875: 1871: 1865: 1822: 1818: 1808: 1765: 1762:J. Cell Biol 1761: 1751: 1716: 1712: 1702: 1667: 1663: 1653: 1604: 1598: 1592: 1557: 1553: 1543: 1508: 1504: 1494: 1461: 1457: 1430: 1385: 1381: 1371: 1344: 1340: 1330: 1321: 1312: 1303: 1294: 1191: 1188:Interactions 1159: 1138:cytoskeleton 1128: 1119: 1111: 1107: 1103: 1102: 1028:NP_001344725 1017: 995:NP_001239005 991:NP_001239004 987:NP_001239002 983:NP_001123484 980: 957:NM_001357796 946: 924:NM_001252076 920:NM_001252075 916:NM_001252073 912:NM_001130012 909: 885: 866: 840: 821: 795: 776: 756: 751: 534:carotid body 514:motor neuron 510:aortic valve 418: 411: 138:External IDs 85: 26: 4848:zinc efflux 2757:PDB gallery 2490:(2): 61–8. 1110:(TKA-1) or 377:24,869,301 364:24,858,260 116:Identifiers 5909:Categories 5874:Cl-oxalate 5869:Cl-formate 5796:Na/glucose 4986:Acetyl-CoA 1289:, May 2017 1268:, May 2017 1244:References 526:right lung 448:right lung 422:(ortholog) 276:2,039,026 263:2,025,356 159:HomoloGene 5893:see also 5765:Symporter 5753:Ion pumps 1990:0021-9258 1941:0021-9258 1892:0363-6127 1839:0021-9738 1782:0021-9525 1735:0021-9258 1686:0021-9258 1629:0028-0836 1576:0021-9258 1527:0021-9258 1478:0006-291X 1024:NP_075938 1020:NP_075542 999:NP_004776 953:NM_023449 949:NM_023055 928:NM_004785 742:Orthologs 538:left lung 167:GeneCards 5862:(Band 3) 5846:Na/(Ca-K 5416:SLC41–48 5369:SLC39A14 5364:SLC39A13 5359:SLC39A12 5354:SLC39A11 5349:SLC39A10 5281:SLC38A10 4922:SLC31–40 4898:SLC30A10 4712:SLC26A11 4707:SLC26A10 4639:SLC25A46 4634:SLC25A45 4629:SLC25A44 4624:SLC25A43 4619:SLC25A42 4614:SLC25A41 4609:SLC25A40 4604:SLC25A39 4599:SLC25A38 4594:SLC25A37 4589:SLC25A36 4584:SLC25A35 4579:SLC25A34 4574:SLC25A33 4569:SLC25A32 4564:SLC25A31 4559:SLC25A30 4554:SLC25A29 4549:SLC25A28 4544:SLC25A27 4539:SLC25A26 4534:SLC25A25 4529:SLC25A24 4524:SLC25A23 4519:SLC25A22 4514:SLC25A21 4509:SLC25A20 4504:SLC25A19 4499:SLC25A18 4494:SLC25A17 4489:SLC25A16 4484:SLC25A15 4479:SLC25A14 4474:SLC25A13 4469:SLC25A12 4464:SLC25A11 4459:SLC25A10 4305:SLC22A20 4300:SLC22A19 4295:SLC22A18 4290:SLC22A17 4285:SLC22A16 4280:SLC22A15 4275:SLC22A14 4270:SLC22A13 4265:SLC22A12 4260:SLC22A11 4255:SLC22A10 4094:SLC21–30 4025:thiamine 3907:SLC16A14 3902:SLC16A13 3897:SLC16A12 3892:SLC16A11 3887:SLC16A10 3615:SLC11–20 3219:chloride 2862:By group 2678:12369822 2648:12080047 2605:12075354 2568:11997330 2539:11948184 2504:11893083 2474:11786550 2439:11751930 2404:11457882 2361:11285285 2318:11118213 2275:10893422 2240:10748023 2205:10455146 1998:10748023 1949:10893422 1900:11997330 1857:11457882 1800:15642748 1743:12080047 1637:12075354 1584:11948184 1535:11751930 1486:12387817 1285:– 1264:– 1232:See also 1194:interact 1178:SLC9A3R1 1156:Function 1120:SLC9A3R2 1076:Wikidata 721:Sources: 681:membrane 171:SLC9A3R2 130:SLC9A3R2 35:SLC9A3R2 5777:Na/K,Cl 5691:SLCO1–4 5651:SLC47A2 5646:SLC47A1 5623:SLC46A2 5618:SLC46A1 5595:SLC45A4 5590:SLC54A3 5585:SLC45A2 5580:SLC45A1 5557:SLC44A5 5552:SLC44A4 5547:SLC44A3 5542:SLC44A2 5537:SLC44A1 5514:SLC43A3 5509:SLC43A2 5504:SLC43A1 5448:SLC41A3 5443:SLC41A2 5438:SLC41A1 5392:SLC40A1 5344:SLC39A9 5339:SLC39A8 5334:SLC39A7 5329:SLC39A6 5324:SLC39A5 5319:SLC39A4 5314:SLC39A3 5309:SLC39A2 5304:SLC39A1 5276:SLC38A6 5271:SLC38A5 5266:SLC38A4 5261:SLC38A3 5256:SLC38A2 5251:SLC38A1 5228:SLC37A4 5223:SLC37A3 5218:SLC37A2 5213:SLC37A1 5187:SLC36A4 5182:SLC36A3 5177:SLC36A2 5172:SLC36A1 5149:SLC35E4 5144:SLC35E3 5139:SLC35E2 5134:SLC35E1 5125:SLC35D3 5120:SLC35D2 5115:SLC35D1 5106:SLC35C2 5101:SLC35C1 5092:SLC35B4 5087:SLC35B3 5082:SLC35B2 5077:SLC35B1 5068:SLC35A5 5063:SLC35A4 5058:SLC35A3 5053:SLC35A2 5048:SLC35A1 5025:SLC34A3 5020:SLC34A2 5015:SLC34A1 4992:SLC33A1 4968:SLC32A1 4945:SLC31A1 4893:SLC30A9 4888:SLC30A8 4883:SLC30A7 4878:SLC30A6 4873:SLC30A5 4868:SLC30A4 4863:SLC30A3 4858:SLC30A2 4853:SLC30A1 4830:SLC29A4 4825:SLC29A3 4820:SLC29A2 4815:SLC29A1 4792:SLC28A3 4787:SLC28A2 4782:SLC28A1 4760:SLC27A6 4755:SLC27A5 4750:SLC27A4 4745:SLC27A3 4740:SLC27A2 4735:SLC27A1 4702:SLC26A9 4697:SLC26A8 4692:SLC26A7 4687:SLC26A6 4682:SLC26A5 4677:SLC26A4 4672:SLC26A3 4667:SLC26A2 4662:SLC26A1 4454:SLC25A9 4449:SLC25A8 4444:SLC25A7 4439:SLC25A6 4434:SLC25A5 4429:SLC25A4 4424:SLC25A3 4419:SLC25A2 4414:SLC25A1 4391:SLC24A6 4386:SLC24A5 4381:SLC24A4 4376:SLC24A3 4371:SLC24A2 4366:SLC24A1 4343:SLC23A4 4338:SLC23A3 4333:SLC23A2 4328:SLC23A1 4250:SLC22A9 4245:SLC22A8 4240:SLC22A7 4235:SLC22A6 4230:SLC22A5 4225:SLC22A4 4220:SLC22A3 4215:SLC22A2 4210:SLC22A1 4186:SLCO6A1 4182:SLCO5A1 4173:SLCO4C1 4168:SLCO4A1 4159:SLCO3A1 4150:SLCO2B1 4145:SLCO2A1 4136:SLCO1C1 4131:SLCO1B4 4126:SLCO1B3 4121:SLCO1B1 4116:SLCO1A2 4070:SLC20A2 4065:SLC20A1 4041:SLC19A3 4036:SLC19A2 4031:SLC19A1 4003:SLC18A3 3998:SLC18A2 3993:SLC18A1 3970:SLC17A9 3965:SLC17A8 3960:SLC17A7 3955:SLC17A6 3950:SLC17A5 3945:SLC17A4 3940:SLC17A3 3935:SLC17A2 3930:SLC17A1 3882:SLC16A9 3877:SLC16A8 3872:SLC16A7 3867:SLC16A6 3862:SLC16A5 3857:SLC16A4 3852:SLC16A3 3847:SLC16A2 3842:SLC16A1 3818:SLC15A4 3813:SLC15A3 3808:SLC15A2 3803:SLC15A1 3780:SLC14A2 3775:SLC14A1 3752:SLC13A5 3747:SLC13A4 3742:SLC13A3 3737:SLC13A2 3732:SLC13A1 3709:SLC12A9 3704:SLC12A8 3699:SLC12A7 3694:SLC12A6 3689:SLC12A5 3684:SLC12A4 3679:SLC12A3 3674:SLC12A2 3669:SLC12A1 3642:SLC11A2 3637:SLC11A1 3571:SLC10A7 3566:SLC10A6 3561:SLC10A5 3556:SLC10A4 3551:SLC10A3 3546:SLC10A2 3541:SLC10A1 3518:SLC9A11 3513:SLC9A10 3412:SLC7A14 3407:SLC7A13 3402:SLC7A11 3397:SLC7A10 3323:SLC6A20 3318:SLC6A19 3313:SLC6A18 3308:SLC6A17 3303:SLC6A16 3298:SLC6A15 3293:SLC6A14 3288:SLC6A13 3283:SLC6A12 3278:SLC6A11 3273:SLC6A10 2877:SLC1–10 2708:PDBe-KB 2698:UniProt 2613:4379134 2585:Bibcode 2352:2185518 2170:9831664 2140:9748260 2105:9314537 2096:2139813 2062:9096337 2030:Bibcode 1791:2171597 1694:9748260 1645:4379134 1609:Bibcode 1422:9671706 1390:Bibcode 1363:9054412 1287:Ensembl 1266:Ensembl 1150:nucleus 1116:protein 854:UniProt 809:Ensembl 748:Species 727:QuickGO 691:nucleus 397:pattern 255:16p13.3 155:1890662 123:Aliases 4939:copper 4021:folate 3508:SLC9A9 3503:SLC9A8 3498:SLC9A7 3493:SLC9A6 3488:SLC9A5 3483:SLC9A4 3478:SLC9A3 3473:SLC9A2 3468:SLC9A1 3445:SLC8A3 3440:SLC8A2 3435:SLC8A1 3392:SLC7A9 3387:SLC7A8 3382:SLC7A7 3377:SLC7A6 3372:SLC7A5 3359:SLC7A4 3354:SLC7A3 3349:SLC7A2 3344:SLC7A1 3268:SLC6A9 3263:SLC6A8 3258:SLC6A7 3253:SLC6A6 3248:SLC6A5 3243:SLC6A4 3238:SLC6A3 3233:SLC6A2 3228:SLC6A1 3217:- and 3215:sodium 3142:SLC5A1 3069:SLC4A1 3041:SLC3A1 2952:SLC2A1 2899:SLC1A1 2703:Q15599 2676:  2646:  2611:  2603:  2577:Nature 2566:  2537:  2502:  2472:  2437:  2402:  2395:203027 2392:  2359:  2349:  2316:  2309:305881 2306:  2288:EMBO J 2273:  2238:  2203:  2168:  2138:  2103:  2093:  2060:  2050:  1996:  1988:  1947:  1939:  1898:  1890:  1855:  1848:203027 1845:  1837:  1798:  1788:  1780:  1741:  1733:  1692:  1684:  1643:  1635:  1627:  1600:Nature 1582:  1574:  1533:  1525:  1484:  1476:  1420:  1410:  1361:  1172:, and 1162:SLC9A3 1146:SLC9A3 1062:search 1060:PubMed 887:Q9JHL1 868:Q15599 764:Entrez 568:BioGPS 147:606553 18:NHERF2 5841:Na/Ca 5791:Na/Cl 5662:(48): 5634:(47): 5606:(46): 5568:(45): 5525:(44): 5492:(43): 5459:(42): 5426:(41): 5380:(40): 5292:(39): 5239:(38): 5201:(37): 5160:(36): 5036:(35): 5003:(34): 4979:(33): 4956:(32): 4932:(31): 4841:(30): 4803:(29): 4771:(28): 4723:(27): 4650:(26): 4402:(25): 4354:(24): 4316:(23): 4198:(22): 4104:(21): 4052:(20): 4014:(19): 3981:(18): 3918:(17): 3829:(16): 3791:(15): 3763:(14): 3720:(13): 3656:(12): 3625:(11): 3529:(10): 2849:TC 2A 2609:S2CID 2053:20313 1641:S2CID 1413:21104 1226:PLCB3 1218:PODXL 1196:with 1174:colon 1135:actin 797:65962 757:Mouse 752:Human 723:Amigo 420:Mouse 413:Human 360:Start 295:Mouse 259:Start 192:Human 163:56962 5848:) - 5836:Na/H 5806:Cl/K 5801:Na/I 5782:Na/P 5726:O4A1 5721:O431 5716:O2B1 5711:O1B3 5706:O1B1 5701:O1A2 5481:RhCG 5476:RhBG 5471:RhAG 5190:36A2 3645:11A3 3593:10A7 3588:10A3 3583:10A2 3578:10A1 3456:(9): 3423:(8): 3334:(7): 3208:(6): 3130:(5): 3057:(4): 3028:(3): 2940:(2): 2887:(1): 2790:2ocs 2775:2he4 2696:for 2674:PMID 2644:PMID 2601:PMID 2564:PMID 2535:PMID 2500:PMID 2470:PMID 2435:PMID 2400:PMID 2357:PMID 2314:PMID 2271:PMID 2236:PMID 2201:PMID 2166:PMID 2150:Gene 2136:PMID 2101:PMID 2058:PMID 1994:PMID 1986:ISSN 1945:PMID 1937:ISSN 1896:PMID 1888:ISSN 1853:PMID 1835:ISSN 1796:PMID 1778:ISSN 1739:PMID 1731:ISSN 1690:PMID 1682:ISSN 1633:PMID 1625:ISSN 1580:PMID 1572:ISSN 1531:PMID 1523:ISSN 1482:PMID 1474:ISSN 1418:PMID 1359:PMID 1224:and 1180:and 1124:gene 778:9351 403:Bgee 351:Band 312:Chr. 250:Band 209:Chr. 143:OMIM 100:4P0C 96:2OCS 92:2HE4 88:2D11 69:RCSB 66:PDBe 5852:HCO 5850:Cl/ 2694:PDB 2666:doi 2634:doi 2630:277 2593:doi 2581:417 2556:doi 2552:282 2525:doi 2521:277 2492:doi 2460:doi 2456:277 2425:doi 2421:277 2390:PMC 2382:doi 2378:108 2347:PMC 2339:doi 2335:153 2304:PMC 2296:doi 2261:doi 2257:275 2226:doi 2222:275 2191:doi 2187:274 2158:doi 2154:222 2126:doi 2122:273 2091:PMC 2083:doi 2079:139 2048:PMC 2038:doi 1976:doi 1972:275 1927:doi 1923:275 1880:doi 1876:282 1843:PMC 1827:doi 1823:108 1786:PMC 1770:doi 1766:168 1721:doi 1717:277 1672:doi 1668:273 1617:doi 1605:417 1562:doi 1558:277 1513:doi 1509:277 1466:doi 1462:298 1408:PMC 1398:doi 1349:doi 1345:272 1214:EZR 1198:SGK 373:End 272:End 175:OMA 151:MGI 59:PDB 5911:: 5767:, 3197:12 3192:11 3187:10 3119:11 3114:10 3017:14 3012:13 3007:12 3002:11 2997:10 2840:: 2836:, 2700:: 2672:. 2662:41 2660:. 2642:. 2628:. 2624:. 2607:. 2599:. 2591:. 2579:. 2562:. 2550:. 2533:. 2519:. 2515:. 2498:. 2488:81 2486:. 2468:. 2454:. 2450:. 2433:. 2419:. 2415:. 2398:. 2388:. 2376:. 2372:. 2355:. 2345:. 2333:. 2329:. 2312:. 2302:. 2292:19 2290:. 2286:. 2269:. 2255:. 2251:. 2234:. 2220:. 2216:. 2199:. 2185:. 2181:. 2164:. 2152:. 2134:. 2120:. 2116:. 2099:. 2089:. 2077:. 2073:. 2056:. 2046:. 2036:. 2026:94 2024:. 2020:. 1992:. 1984:. 1970:. 1966:. 1943:. 1935:. 1921:. 1917:. 1894:. 1886:. 1874:. 1851:. 1841:. 1833:. 1821:. 1817:. 1794:. 1784:. 1776:. 1764:. 1760:. 1737:. 1729:. 1715:. 1711:. 1688:. 1680:. 1666:. 1662:. 1639:. 1631:. 1623:. 1615:. 1603:. 1578:. 1570:. 1556:. 1552:. 1529:. 1521:. 1507:. 1503:. 1480:. 1472:. 1460:. 1444:^ 1416:. 1406:. 1396:. 1386:95 1384:. 1380:. 1357:. 1343:. 1339:. 1320:. 1302:. 1273:^ 1252:^ 1228:. 1220:, 1216:, 1212:, 1208:, 1204:, 1200:, 1168:, 1152:. 1126:. 725:/ 379:bp 366:bp 278:bp 265:bp 173:; 169:: 165:; 161:: 157:; 153:: 149:; 145:: 98:, 94:, 90:, 5857:3 5816:5 5811:4 5786:3 5784:i 4780:( 4188:) 4184:( 4023:/ 3182:9 3177:8 3172:7 3167:6 3162:5 3157:4 3152:3 3147:2 3109:9 3104:8 3099:7 3094:6 3089:5 3084:4 3079:3 3074:2 3046:2 2992:9 2987:8 2982:7 2977:6 2972:5 2967:4 2962:3 2957:2 2929:7 2924:6 2919:5 2914:4 2909:3 2904:2 2851:) 2847:( 2826:e 2819:t 2812:v 2750:e 2743:t 2736:v 2723:. 2710:. 2680:. 2668:: 2650:. 2636:: 2615:. 2595:: 2587:: 2570:. 2558:: 2541:. 2527:: 2506:. 2494:: 2476:. 2462:: 2441:. 2427:: 2406:. 2384:: 2363:. 2341:: 2320:. 2298:: 2277:. 2263:: 2242:. 2228:: 2207:. 2193:: 2172:. 2160:: 2142:. 2128:: 2107:. 2085:: 2064:. 2040:: 2032:: 2000:. 1978:: 1951:. 1929:: 1902:. 1882:: 1859:. 1829:: 1802:. 1772:: 1745:. 1723:: 1696:. 1674:: 1647:. 1619:: 1611:: 1586:. 1564:: 1537:. 1515:: 1488:. 1468:: 1438:. 1424:. 1400:: 1392:: 1365:. 1351:: 1324:. 1306:. 297:) 194:) 177:: 20:)

Index

NHERF2

PDB
PDBe
RCSB
2D11
2HE4
2OCS
4P0C
Aliases
SLC9A3R2
OMIM
606553
MGI
1890662
HomoloGene
56962
GeneCards
SLC9A3R2
OMA
SLC9A3R2 - orthologs
Human
Chromosome 16 (human)
Chr.
Chromosome 16 (human)
Chromosome 16 (human)
Genomic location for SLC9A3R2
Genomic location for SLC9A3R2
Band
bp

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