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NanoString Technologies

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Geiss, Gary K; Bumgarner, Roger E; Birditt, Brian; Dahl, Timothy; Dowidar, Naeem; Dunaway, Dwayne L; Fell, H Perry; Ferree, Sean; George, Renee D; Grogan, Tammy; James, Jeffrey J; Maysuria, Malini; Mitton, Jeffrey D; Oliveri, Paola; Osborn, Jennifer L; Peng, Tao; Ratcliffe, Amber L; Webster, Philippa
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raised funding to expand NanoString sales and marketing. NanoString’s first spatial platform, the GeoMx DSP, was launched in 2019, enabling highly multiplexed spatial profiling of RNA and protein targets in various sample types, including FFPE tissue sections. The unique combination of high-plex and
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The original patent forming the basis for the nCounter Analysis System was invented and licensed by The Institute for Systems Biology. The business plan was written by Amber Ratcliffe and Aaron Coe and won seed funding in multiple business plan competitions. NanoString was spun out of The Institute
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In addition, NanoString has developed the AtoMx Spatial Informatics Platform, a cloud-based informatics solution with advanced analytics and global collaboration capabilities, which is expected to launch in 2022. The AtoMx platform provides a comprehensive, integrated ecosystem for spatial biology
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As of June 2010, the company was not yet profitable. In an interview, Gray suggested that NanoString would begin to develop clinical diagnostics. As of July 2012, NanoString began indicating a move towards becoming a public company by hiring several senior staff with public company experience.
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NanoString's products include the nCounter Gene Expression System, the GeoMx Digital Spatial Profiler, the CosMx Spatial Molecular Imager, and the AtoMx Spatial Informatics Platform. These four systems enable scientists to envision molecular interactions in three dimensions and see the
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To enable spatial transcriptomics and proteomics from one FFPE slide, NanoString introduced the GeoMx Digital Spatial Profiler in 2019. The GeoMx DSP combines whole tissue imaging with gene expression and protein data for single cell resolution in a spatial context.
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Overall, NanoString's continued investment in innovation has led to the development of a range of advanced research tools that offer high sensitivity, precision, and spatial resolution, allowing researchers to gain deep insights into biological systems.
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was approved and later that month Bruker announced a definitive acquisition agreement had been entered between the companies. Bruker acquired the assets and rights associated with NanoString's business for $ 392.6 million in cash.
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high-throughput spatial profiling allows researchers to rapidly and quantitatively assess the biological implications of heterogeneity within tissues and has resulted in over 150 peer-reviewed publications as of September 2022.
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platform that is FFPE-compatible and powered by spatial multiomics. It allows researchers to map single cells in their native environments to extract deep biological insights and novel discoveries from one experiment.
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In 2009, Perry Fell, who had been CEO since 2004, left the company abruptly without official explanation. Between 2009 and 2010, the company operated with an acting CEO, Wayne Burns. Brad Gray, a former
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expression of genes and proteins in the context of tissue structure. NanoString products are based on a novel digital molecular barcoding technology invented at the
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after laying off 20% of its workforce in October 2023. The company began exploring options to support its restructuring, including a potential sale of itself.
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In 2008, NanoString launched the nCounter Analysis System and began international sales operations with its first multiplexed assays for
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nCounter® Analysis System, GeoMx® Digital Spatial Profiler, CosMx ™ Spatial Molecular Imager, AtoMx ™ Spatial Informatics Portal
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for Systems Biology and founded as a separate company in 2003 by Krassen Dimitrov, Amber Ratcliffe, and Dwayne Dunaway.
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technology. The nCounter system allows for the simultaneous profiling of hundreds of genes, proteins,
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NanoString's research tools are based on the nCounter Analysis System, which is a modification of the
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NanoString's product pipeline includes the development of the CosMx Spatial Molecular Imager, a
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Annie Zak (20 March 2015). "NanoString pulls in 52% more sales".
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On April 19, 2024, the sale of NanoString Technologies to the
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J; Davidson, Eric H; Hood, Leroy; Dimitrov, Krassen (2008).
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insights, enabling global data sharing and collaboration.
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On February 4, 2024, NanoString Technologies filed for
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Companies that filed for Chapter 11 bankruptcy in 2024
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Bizjournals.com. 2003-05-27 281:Institute for Systems Biology 265:NanoString Technologies, Inc. 399:Puget Sound Business Journal 86:NanoString Technologies, Inc 750:(Press release). 2022-06-06 729:(Press release). 2019-03-06 449:(Press release). 2022-03-01 283:under the direction of Dr. 234:$ 479.5 million (2021) 222:-$ 80.1 million (2021) 210:$ 144.0 million (2021) 1686: 1650:Companies based in Seattle 1137:NHS Connecting for Health 342:Technology & Products 90: 1624:Category:Health software 1132:NHS Care Records Service 1116:Microtest Open Evolution 1502:Psychtoolbox for MATLAB 318:In 2013, the company's 269:translational research 585:. Xconomy. 2012-07-18 564:. Xconomy. 2010-06-29 536:. Xconomy. 2009-03-24 328:Chapter 11 bankruptcy 202:nCounter®, GeoMx® DSP 55:neutral point of view 16:Biotechnology company 685:Nature Biotechnology 1360:Practice Management 1169:Summary Care Record 1044:Certify HealthLogix 510:"biotechnologie.de" 363:single-cell imaging 240:Number of employees 168:Seattle, Washington 87: 47:promotional content 1447:Patient engagement 1315:athenaCommunicator 1127:NextGen Healthcare 665:, since abandoned. 610:. 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NSTGQ
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Biotechnology
South Lake Union
Seattle, Washington
United States
Net income
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nanostring.com
translational research
multiomic
Institute for Systems Biology
Leroy Hood
gene expression
Genzyme
IPO
Chapter 11 bankruptcy
Bruker Corporation
DNA microarray
miRNAs

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