Knowledge (XXG)

National Institute of General Medical Sciences

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understanding the principles, mechanisms, and processes that underlie living organisms, often using research models. NIGMS also supports the development of fundamental methods and new technologies to achieve its mission. NIGMS-supported research may utilize specific cells or organ systems if they serve as models for understanding general principles. Research with the overall goal to gain knowledge about a specific organ or organ system or the pathophysiology, treatment, or cure of a specific disease or condition will, in most cases, be more appropriate for another Institute or Center. See the NIH listing of Institutes, Centers, and Offices to learn more about their specific missions.
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and lays the foundation for advances in disease diagnosis, treatment, and prevention. NIGMS-funded scientists investigate how living systems work at a range of levels, from molecules and cells to tissues and organs, in research organisms, humans, and populations. Additionally, to ensure the vitality
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All NIH Institutes and Centers support basic research that is relevant to the diseases, organ systems, stages of life, or populations within their mission areas. In contrast, NIGMS supports fundamental research that does not focus on those specific areas. NIGMS' research mission is aimed at
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NIGMS also supports research in specific clinical areas that affect multiple organ systems: anesthesiology and peri-operative pain; sepsis; clinical pharmacology that is common to multiple drugs and treatments; and trauma, burn injury, and wound healing.
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and continued productivity of the research enterprise, NIGMS provides leadership in training the next generation of scientists, in enhancing the diversity of the scientific workforce, and in developing research capacity throughout the country.
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to scientists at universities, medical schools, hospitals, and other research institutions throughout the country. At any given time, NIGMS supports more than 3,000 investigators and 4,000
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Shedding light on the critical functions of carbohydrates, sugar molecules found on all living cells that are vital to fertilization, inflammation, blood clotting and viral infection.
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Developing new methods to look inside cells and other living systems. These approaches have advanced what we know about basic life processes in a range of organisms.
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Modeling infectious disease outbreaks and the impact of interventions through computer simulations to provide valuable information to public health policymakers.
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NIGMS is organized into the following divisions that support research, research training, and capacity building in a range of scientific fields.
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Revealing how a protein's shape affects its function, which plays a key role in health and disease and also informs the design of new drugs.
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NIGMS was established in 1962. In Fiscal Year 2017, the institute's budget was $ 2.6 billion. The vast majority of this money funds
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Increasing survival from burn injury, in part by improving methods of wound care, nutrition and infection control.
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Jon Lorsch, Ph.D., director of the National Institute of General Medical Sciences
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NIGMS produces a number of free science education materials on topics such as
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Division of Biophysics, Biomedical Technology, and Computational Biosciences
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Division of Genetics and Molecular, Cellular, and Developmental Biology
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National Institute of Arthritis and Musculoskeletal and Skin Diseases
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Among the advances that scientists have made with NIGMS support are:
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Discovering a gene-silencing process called RNA interference, or
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National Institute of Diabetes and Digestive and Kidney Diseases
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National Institute on Deafness and Other Communication Disorders
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Division of Pharmacology, Physiology, and Biological Chemistry
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National Institute on Minority Health and Health Disparities
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National Institute of Biomedical Imaging and Bioengineering
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Division of Training, Workforce Development, and Diversity
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National Center for Complementary and Integrative Health
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National Institute of Child Health and Human Development
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National Institute of Neurological Disorders and Stroke
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National Institutes of Health Director's Pioneer Award
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National Institute of Dental and Craniofacial Research
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National Institute of General Medical Sciences (NIGMS)
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National Institute of Allergy and Infectious Diseases
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National Center for Advancing Translational Sciences
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Medical research agency of the US Federal Government
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National Institute of Environmental Health Sciences
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The institute also produces the magazine 891: 877: 869: 930:National Heart, Lung, and Blood Institute 935:National Human Genome Research Institute 216: 138: 461: 160:Division for Research Capacity Building 61:Department of Health and Human Services 34:Federal Government of the United States 1243:National Center for Research Resources 1015:National Institute of Nursing Research 18: 7: 1248:National Institutes of Health Police 1228:National Institutes of Health campus 1046:John E. Fogarty International Center 1253:Office of Laboratory Animal Welfare 1218:United States Public Health Service 1092:National Diabetes Education Program 1000:National Institute of Mental Health 474:National Institutes of Health (NIH) 118:National Institutes of Health (NIH) 14: 1036:Center for Information Technology 985:National Institute on Drug Abuse 838: 402: 384: 364: 346: 328: 310: 290: 270: 252: 234: 108:that increases understanding of 1223:Division of Intramural Research 1: 1316:National Institutes of Health 1266:indicate acting officeholders 901:National Institutes of Health 391:Judith H. Greenberg (acting) 353:Judith H. Greenberg (acting) 71:National Institutes of Health 1041:Center for Scientific Review 1020:National Library of Medicine 214:Past Directors 1962–present 124:. NIH is a component of the 940:National Institute on Aging 1337: 1261: 920:National Cancer Institute 1238:NIH Public Access Policy 317:Marvin Cassman (acting) 1150:James Augustine Shannon 1061:Vaccine Research Center 1145:William H. Sebrell, Jr 925:National Eye Institute 144: 1292:38.99722°N 77.09972°W 1165:Donald S. Fredrickson 1087:Visible Human Project 200:computational biology 142: 847:at Wikimedia Commons 711:"Structural Biology" 456:Notes and references 116:NIGMS is one of the 110:biological processes 1297:38.99722; -77.09972 1288: /  1170:James B. Wyngaarden 298:Ruth L. Kirschstein 259:Frederick L. Stone 21: 1195:Monica Bertagnolli 811:"Cellular Imaging" 278:DeWitt Stetten Jr. 241:Clinton C. Powell 196:structural biology 145: 122:Federal Government 1271: 1270: 1155:Robert Q. Marston 1135:Lewis R. Thompson 1120:Milton J. Rosenau 1115:Joseph J. Kinyoun 843:Media related to 815:www.nigms.nih.gov 740:www.nigms.nih.gov 715:www.nigms.nih.gov 693:www.nigms.nih.gov 671:"NIGMS Directors" 600:www.nigms.nih.gov 575:www.nigms.nih.gov 550:www.nigms.nih.gov 525:www.nigms.nih.gov 500:www.nigms.nih.gov 424:Research advances 421: 420: 104:) supports basic 94: 93: 57:Parent department 49:, Ph.D., Director 1328: 1303: 1302: 1300: 1299: 1298: 1293: 1289: 1286: 1285: 1284: 1281: 1180:Harold E. Varmus 1125:John F. Anderson 1097:BRAIN Initiative 893: 886: 879: 870: 856: 855: 853:Official website 842: 826: 825: 823: 821: 807: 801: 800: 798: 797: 788:. Archived from 782: 776: 775: 773: 772: 763:. Archived from 757: 751: 750: 748: 746: 732: 726: 725: 723: 721: 707: 701: 700: 695:. Archived from 685: 679: 678: 667: 661: 660: 658: 657: 648:. Archived from 642: 636: 635: 633: 632: 623:. 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Index

Federal Government of the United States
Jon Lorsch
Department of Health and Human Services
National Institutes of Health
www.nigms.nih.gov
research
biological processes
National Institutes of Health (NIH)
Federal Government
U.S. Department of Health and Human Services
Head shot of Dr. Jon Lorsch, director of the National Institute of General Medical Sciences
grants
research grants
cell biology
genetics
chemistry
pharmacology
structural biology
computational biology



DeWitt Stetten Jr.

Ruth L. Kirschstein




Jeremy M. Berg

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