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Brockdorff, Neil; Ashworth, Alan; Kay, Graham F.; McCabe, Veronica M.; Norris, Dominic P.; Cooper, Penny J.; Swift, Sally; Rastan, Sohaila (1992). "The product of the mouse Xist gene is a 15 kb inactive X-specific transcript containing no conserved ORF and located in the nucleus".
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Stock, Julie K.; Giadrossi, Sara; Casanova, Miguel; Brookes, Emily; Vidal, Miguel; Koseki, Haruhiko; Brockdorff, Neil; Fisher, Amanda G.; Pombo, Ana (2007). "Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells".
279:, controls the X inactivation process. Building on this finding he has elucidated key steps in XIST gene regulation during early development, and has defined major pathways through which XIST RNA induces chromosome wide
588:
de
Napoles, Mariana; Mermoud, Jacqueline E.; Wakao, Rika; Tang, Y.Amy; Endoh, Mitusuhiro; Appanah, Ruth; Nesterova, Tatyana B.; Silva, Jose; Otte, Arie P.; Vidal, Miguel; Koseki, Haruhiko; Brockdorff, Neil (2004).
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Penny, Graeme D.; Kay, Graham F.; Sheardown, Steven A.; Rastan, Sohaila; Brockdorff, Neil (1996). "Requirement for Xist in X chromosome inactivation".
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591:"Polycomb Group Proteins Ring1A/B Link Ubiquitylation of Histone H2A to Heritable Gene Silencing and X Inactivation"
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The effect of oestradiol-17Ξ² on the ribonucleases and ribonuclease inhibitor of immature rat uterus
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The effect of oestradiol-17Ξ² on the ribonucleases and ribonuclease inhibitor of immature rat uterus
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One or more of the preceding sentences incorporates text from the royalsociety.org website where:
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regulation in mammalian development. His interests are in the molecular basis of
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proteins around which DNA is packaged, contribute to gene regulation in
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Fellows of the
Academy of Medical Sciences (United Kingdom)
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X inactivation is an important model for understanding how
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Members of the
European Molecular Biology Organization
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Creative
Commons Attribution 4.0 International License
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765:"Preface: X-chromosome inactivation and Mary Lyon"
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216:, the process that evolved in mammals to equalise
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355:Philosophical Transactions of the Royal Society B
350:"Polycomb complexes in X chromosome inactivation"
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428: ed.). Oxford: A & C Black.
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192:(born 1958) is a British biochemist who is a
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570:Royal Society Terms, conditions and policies
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449:Brockdorff, Neil Alexander Steven (1985).
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301:Fellow of the Academy of Medical Sciences
259:mechanisms, for example modification of
194:Wellcome Trust Principal Research Fellow
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293:European Molecular Biology Organization
305:Fellow of the Royal Society of Biology
204:. Brockdorff's research investigates
1366:Academics of the University of Oxford
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459:(PhD thesis). University of Glasgow.
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7:
1356:Alumni of the University of Glasgow
196:and professor in the department of
1361:Alumni of the University of Sussex
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223:levels in XX females relative to
1304: This article incorporates
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190:Neil Alexander Steven Brockdorff
66:Neil Alexander Steven Brockdorff
545:"Professor Neil Brockdorff FRS"
324:"EMBO MEMBER: Neil Brockdorff"
291:Brockdorff is a member of the
16:British biochemist (born 1958)
1:
1331:Fellows of the Royal Society
723:10.1016/0092-8674(92)90519-I
608:10.1016/j.devcel.2004.10.005
433:UK public library membership
763:; Brockdorff, Neil (2017).
297:Fellow of the Royal Society
235:Brockdorff was educated at
69:1958 (age 65–66)
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1227:(Baron Willetts of Havant)
576: (archived 2016-11-11)
348:Brockdorff, Neil (2017).
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122:Developmental epigenetics
110:
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415:"Brockdorff, Prof. Neil"
426:Oxford University Press
52:Neil Brockdorff at the
783:10.1098/rstb.2016.0353
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368:10.1098/rstb.2017.0021
833:Europe PubMed Central
269:developmental biology
245:University of Glasgow
93:University of Glasgow
1308:available under the
241:University of Sussex
202:University of Oxford
136:University of Oxford
88:University of Sussex
56:in London, July 2018
1124:Lalita Ramakrishnan
1084:Dominic Kwiatkowski
848:Nature Cell Biology
661:1996Natur.379..131P
251:Career and research
1199:Geordie Williamson
994:Vincenzo Cerundolo
831:publications from
595:Developmental Cell
516:www.bioch.ox.ac.uk
473:uk.bl.ethos.379306
287:Awards and honours
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1024:Gregory Edgecombe
855:(12): 1428β1435.
655:(6561): 131β137.
431:(Subscription or
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112:Scientific career
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1267:Albrecht Hofmann
1262:Fabiola Gianotti
1257:Jeffrey Friedman
1252:Sebsebe Demissew
1242:Carolyn Bertozzi
1209:Nikolay Zheludev
1154:Michelle Simmons
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1004:Robert Crabtree
984:Neil Brockdorff
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1114:Tracy Palmer
1064:Harren Jhoti
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989:Frank Caruso
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331:. Retrieved
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218:X chromosome
198:biochemistry
189:
188:
147:
132:Institutions
111:
18:
1371:1958 births
1204:Daniel Wise
1074:Andrew King
1034:Roger Goody
1014:Peter Dayan
870:10261/61600
181:/brockdorff
104:EMBO Member
1320:Categories
1287:Adi Shamir
1129:Nancy Reid
1054:Judy Hirst
1029:Wenfei Fan
551:. London:
457:jisc.ac.uk
435:required.)
311:References
295:(EMBO), a
275:molecule,
257:epigenetic
1310:CC BY 4.0
1159:John Smol
1099:Elon Musk
879:1465-7392
791:0962-8436
731:0092-8674
677:0028-0836
617:1534-5807
465:301485805
421:Who's Who
376:0962-8436
299:(FRS), a
231:Education
179:/research
74:Education
1312:license.
1218:Honorary
948:elected
887:18037880
809:28947653
777:(1733).
747:19889657
625:15525528
424:(online
394:28947664
362:(1733).
307:(FRSB).
225:XY males
1235:Foreign
957:Fellows
950:in 2018
944:of the
942:Fellows
895:2317691
800:5627156
739:1423610
693:4329368
685:8538762
657:Bibcode
572:at the
521:12 June
496:12 June
385:5627167
333:12 June
265:histone
247:(PhD).
200:at the
164:Website
34:FMedSci
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239:, the
210:genome
171:.bioch
154:(1985)
152:
143:Thesis
118:Fields
106:(1999)
100:Awards
891:S2CID
743:S2CID
689:S2CID
568:.β --
469:EThOS
95:(PhD)
90:(BSc)
36:
32:
1306:text
883:PMID
875:ISSN
805:PMID
787:ISSN
735:PMID
727:ISSN
710:Cell
681:PMID
673:ISSN
621:PMID
613:ISSN
523:2018
498:2018
461:OCLC
390:PMID
372:ISSN
335:2018
277:XIST
263:and
208:and
206:gene
62:Born
38:FRSB
865:hdl
857:doi
795:PMC
779:doi
775:372
719:doi
665:doi
653:379
603:doi
380:PMC
364:doi
360:372
273:RNA
261:DNA
177:.uk
175:.ac
173:.ox
169:www
30:FRS
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Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
