555:
Abyar, Selda; Khandar, Ali Akbar; Salehi, Roya; Abolfazl
Hosseini-Yazdi, Seyed; Alizadeh, Effat; Mahkam, Mehrdad; Jamalpoor, Amer; White, Jonathan M.; Shojaei, Motahhareh; Aizpurua-Olaizola, O.; Masereeuw, Rosalinde (December 2019).
279:
Drug-induced glomerular disease is not common but there are a few drugs that have been implicated. Glomerular lesions occur primarily through immune-mediated pathways rather than through direct drug toxicity.
53:
Nephrotoxicity should not be confused with some medications predominantly excreted by the kidneys needing their dose adjusted for the decreased kidney function (e.g.,
805:
410:, which may be more useful clinically when dealing with patients with early kidney disease. Normal creatinine level is between 80 - 120 μmol/L.
400:
indicates poor kidney function. In interventional radiology, a patient's creatinine clearance levels are all checked prior to a procedure.
366:, found in some plants and in some herbal supplements derived from those plants, has been shown to have nephrotoxic effects on humans.
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39:
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35:
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716:
Choudhury, Devasmita; Ahmed, Ziauddin (2006). "Drug-associated renal dysfunction and injury".
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187:
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46:. There are various forms, and some drugs may affect kidney function in more than one way.
407:
43:
573:
598:
558:"In vitro nephrotoxicity and anticancer potency of newly synthesized cadmium complexes"
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532:
328:
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132:
120:
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300:
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Nephrotoxicity is usually monitored through a simple blood test. A decreased
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27:
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contains some nephrotoxins which can cause inflammation of the
473:
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467:
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755:"Nephrotoxicity related to new therapeutic compounds"
464:
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291:
are known to cause focal segmental glomerulosclerosis
470:
446:
440:
320:—reversible at low doses, irreversible at high doses
455:
702:USMLE WORLD QBanks 2009, Step1, Pharmacology, Q74
654:
652:
8:
50:are substances displaying nephrotoxicity.
770:
676:
597:
698:
696:
659:Naesens M, Kuypers DR, Sarwal M (2009).
297:therapy can cause membranous nephropathy
544:
661:"Calcineurin inhibitor nephrotoxicity"
623:"Can acute renal failure be prevented"
7:
550:
548:
718:Nature Clinical Practice Nephrology
14:
424:
160:), ACE inhibitors, ciclosporin,
806:Toxins by organ system affected
503:, yielding "kidney poisoning".
258:Chronic interstitial nephritis
1:
753:Szeto, CC; Chow, KM (2005).
513:Contrast-induced nephropathy
307:Causes of diabetes insipidus
205:Acute interstitial nephritis
199:Acute interstitial nephritis
38:, both toxic chemicals and
827:
582:10.1038/s41598-019-51109-9
109:Proximal convoluted tubule
665:Clin. J. Am. Soc. Nephrol
382:, aka food additive E297
275:Acute glomerulonephritis
16:Toxicity in the kidneys
406:is another measure of
174:Tubular obstruction:
103:Direct tubular effect
678:10.2215/CJN.04800908
398:creatinine clearance
211:β-lactam antibiotics
203:Main article :
730:10.1038/ncpneph0076
627:J R Coll Surg Edinb
574:2019NatSR...914686A
115:antibiotics (e.g.,
621:Galley HF (2000).
562:Scientific Reports
340:Other nephrotoxins
772:10.1081/jdi-56595
364:Aristolochic acid
188:diethylene glycol
61:Types of toxicity
818:
792:
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656:
647:
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641:. Archived from
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404:Serum creatinine
166:cyclophosphamide
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710:Further reading
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483:combining forms
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408:kidney function
394:
376:in some people.
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309:
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133:immunoglobulins
105:
68:
63:
44:kidney function
34:effect of some
17:
12:
11:
5:
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813:
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671:(2): 481–509.
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645:on 2005-10-18.
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533:Onconephrology
530:
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420:nephrotoxicity
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341:
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329:Demeclocycline
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318:Amphotericin B
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200:
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170:amphotericin B
139:
121:amphotericin B
113:Aminoglycoside
104:
101:
100:
99:
88:ACE inhibitors
84:
67:
66:Cardiovascular
64:
62:
59:
20:Nephrotoxicity
15:
13:
10:
9:
6:
4:
3:
2:
823:
812:
809:
807:
804:
803:
801:
790:
786:
782:
778:
773:
768:
765:(3): 329–33.
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760:
759:Renal Failure
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531:
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523:Neurotoxicity
521:
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327:
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316:
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313:Lithium salts
311:
310:
306:
302:
301:Penicillamine
299:
296:
293:
290:
286:
283:
282:
281:
274:
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264:Lithium salts
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261:
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227:ciprofloxacin
224:
223:sulphonamides
220:
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176:sulphonamides
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162:lithium salts
159:
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142:Distal tubule
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129:radiocontrast
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37:
33:
29:
25:
21:
762:
758:
724:(2): 80–91.
721:
717:
668:
664:
643:the original
633:(1): 44–50.
630:
626:
616:
568:(1): 14686.
565:
561:
498:
492:
486:
419:
417:
402:
395:
380:Fumaric acid
278:
202:
180:methotrexate
57:, lithium).
52:
48:Nephrotoxins
47:
19:
18:
528:Ototoxicity
289:Pamidronate
269:Ciclosporin
192:triamterene
92:ciclosporin
81:vasodilator
40:medications
811:Nephrology
800:Categories
539:References
386:Orellanine
295:Gold salts
243:furosemide
239:cimetidine
235:ranitidine
219:rifampicin
215:vancomycin
158:diclofenac
117:gentamicin
96:tacrolimus
77:β-blockers
36:substances
30:. It is a
590:2045-2322
418:The word
414:Etymology
392:Diagnosis
334:Foscarnet
251:phenytoin
247:thiazides
184:aciclovir
154:ibuprofen
125:cisplatin
73:diuretics
71:General:
32:poisonous
781:15957551
746:42733127
738:16932399
687:19218475
639:10815380
608:31604983
518:Toxicity
507:See also
324:Fluoride
137:mannitol
24:toxicity
789:6111262
599:6789105
570:Bibcode
488:nephro-
481:) uses
374:kidneys
370:Rhubarb
358:cadmium
354:mercury
350:Uranium
150:aspirin
131:media,
86:Local:
55:heparin
28:kidneys
26:in the
787:
779:
744:
736:
685:
637:
606:
596:
588:
500:-icity
356:, and
285:Heroin
231:NSAIDs
148:(e.g.
146:NSAIDs
83:agents
785:S2CID
742:S2CID
360:salts
42:, on
777:PMID
734:PMID
683:PMID
635:PMID
604:PMID
586:ISSN
494:tox-
346:Lead
287:and
767:doi
726:doi
673:doi
594:PMC
578:doi
485:of
119:),
22:is
802::
783:.
775:.
763:27
761:.
757:.
740:.
732:.
720:.
695:^
681:.
667:.
663:.
651:^
631:45
629:.
625:.
602:.
592:.
584:.
576:.
564:.
560:.
547:^
497:+
491:+
444:oʊ
352:,
348:,
249:,
245:,
241:,
237:,
233:,
229:,
225:,
221:,
217:,
213:,
190:,
186:,
182:,
178:,
168:,
164:,
156:,
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135:,
127:,
123:,
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94:,
90:,
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75:,
791:.
769::
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728::
722:2
689:.
675::
669:4
610:.
580::
572::
566:9
477:/
474:i
471:t
468:ɪ
465:s
462:ɪ
459:s
456:ˈ
453:k
450:ɒ
447:t
441:r
438:f
435:ɛ
432:n
429:ˌ
426:/
422:(
253:.
194:.
98:.
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