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New England Centenarian Study

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A study of gene tests of hundreds of centenarians reported in July 2010 that genetics plays an extremely important role in deciding who reaches that age. Centenarians rarely develop diseases of aging, and are more likely to bounce back from diseases. Led by Perls, the study was funded by the
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were common, so it transitioned into finding out why some people can live to 100 and others do not. Some findings included that centenarians had natural advantages, including large
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size. Studies for genes managed to identify only one major gene associated with longevity.
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Validation of Exceptional Longevity: Age Validation in the New England Centenarian Study
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Researchers are now investigating more detailed genetic analysis including
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In 2006, an offshoot, the New England Supercentenarian Study, was begun.
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The study began in 1994 and was originally focused on research into
770: 191: 187: 76:'s Division of Geriatrics and Clinical Gerontology. 814: 763: 723: 685: 640: 485: 427: 416: 326: 225: 203: 8: 424: 210: 196: 188: 23:is a study of persons aged 100 and over ( 16:Study of centenarians in the Boston area 116: 7: 183:New England Supercentenarian Study 126:"Genetic Secrets of Living to 100" 14: 353:Biodemography of human longevity 124:Keim, Brandon (July 1, 2010). 57:, the Study is now located at 1: 173:New England Centenarian Study 151:. The Washington Post Company 21:New England Centenarian Study 868:Health in the United States 147:Stein, Rob (July 1, 2010). 74:National Institute on Aging 884: 294:research into centenarians 101:Research into centenarians 363:Longevity escape velocity 250:aging-associated diseases 96:Okinawa Centenarian Study 863:Longevity study projects 842:Longest-living organisms 837:Transhumanist politics 755:Immortality in fiction 733:Biological immortality 277:cognitive epidemiology 53:. Formerly located at 641:regions by continents 260:negligible senescence 255:degenerative diseases 486:regions of countries 306:LGBT life expectancy 827:Longevity insurance 745:Digital immortality 371:calorie restriction 358:Indefinite lifespan 348:Anti-aging movement 318:Biomarkers of aging 477:World macroregions 376:Diet and longevity 55:Harvard University 850: 849: 681: 680: 401:stem-cell therapy 313:Maximum life span 59:Boston University 875: 693:Longevity claims 425: 289:supercentenarian 212: 205: 198: 189: 161: 160: 158: 156: 144: 138: 137: 135: 133: 121: 106:Supercentenarian 883: 882: 878: 877: 876: 874: 873: 872: 853: 852: 851: 846: 810: 764:Longevity genes 759: 719: 677: 636: 481: 420:life expectancy 418: 412: 322: 301:Life expectancy 240:Longevity myths 221: 216: 169: 164: 154: 152: 146: 145: 141: 131: 129: 123: 122: 118: 114: 82: 61:and led by Dr. 17: 12: 11: 5: 881: 879: 871: 870: 865: 855: 854: 848: 847: 845: 844: 839: 834: 832:Longevity risk 829: 824: 818: 816: 812: 811: 809: 808: 803: 798: 793: 788: 783: 778: 773: 767: 765: 761: 760: 758: 757: 752: 747: 742: 741: 740: 729: 727: 721: 720: 718: 717: 716: 715: 710: 705: 695: 689: 687: 683: 682: 679: 678: 676: 675: 670: 665: 660: 655: 650: 644: 642: 638: 637: 635: 634: 633: 632: 627: 617: 612: 607: 602: 597: 592: 587: 582: 577: 572: 567: 562: 557: 552: 547: 542: 537: 532: 527: 526: 525: 515: 510: 505: 500: 495: 489: 487: 483: 482: 480: 479: 474: 469: 464: 459: 458: 457: 452: 442: 437: 431: 429: 422: 414: 413: 411: 410: 409: 408: 403: 398: 393: 391:organ printing 388: 383: 378: 373: 365: 360: 355: 350: 345: 344: 343: 332: 330: 328:Life extension 324: 323: 321: 320: 315: 310: 309: 308: 298: 297: 296: 291: 281: 280: 279: 274: 272:biogerontology 264: 263: 262: 257: 252: 242: 237: 231: 229: 223: 222: 217: 215: 214: 207: 200: 192: 186: 185: 180: 175: 168: 167:External links 165: 163: 162: 139: 115: 113: 110: 109: 108: 103: 98: 93: 88: 81: 78: 15: 13: 10: 9: 6: 4: 3: 2: 880: 869: 866: 864: 861: 860: 858: 843: 840: 838: 835: 833: 830: 828: 825: 823: 820: 819: 817: 813: 807: 804: 802: 799: 797: 794: 792: 789: 787: 784: 782: 779: 777: 774: 772: 769: 768: 766: 762: 756: 753: 751: 750:Eternal youth 748: 746: 743: 739: 736: 735: 734: 731: 730: 728: 726: 722: 714: 711: 709: 706: 704: 701: 700: 699: 698:Oldest people 696: 694: 691: 690: 688: 684: 674: 673:South America 671: 669: 666: 664: 663:North America 661: 659: 656: 654: 651: 649: 646: 645: 643: 639: 631: 628: 626: 623: 622: 621: 618: 616: 613: 611: 608: 606: 603: 601: 598: 596: 593: 591: 588: 586: 583: 581: 578: 576: 573: 571: 568: 566: 563: 561: 558: 556: 553: 551: 548: 546: 543: 541: 538: 536: 533: 531: 528: 524: 521: 520: 519: 516: 514: 511: 509: 506: 504: 501: 499: 496: 494: 491: 490: 488: 484: 478: 475: 473: 470: 468: 465: 463: 460: 456: 455:South America 453: 451: 450:North America 448: 447: 446: 443: 441: 438: 436: 433: 432: 430: 426: 423: 421: 415: 407: 404: 402: 399: 397: 394: 392: 389: 387: 384: 382: 379: 377: 374: 372: 369: 368: 366: 364: 361: 359: 356: 354: 351: 349: 346: 342: 339: 338: 337: 336:Topic outline 334: 333: 331: 329: 325: 319: 316: 314: 311: 307: 304: 303: 302: 299: 295: 292: 290: 287: 286: 285: 282: 278: 275: 273: 270: 269: 268: 265: 261: 258: 256: 253: 251: 248: 247: 246: 243: 241: 238: 236: 233: 232: 230: 228: 224: 220: 213: 208: 206: 201: 199: 194: 193: 190: 184: 181: 179: 176: 174: 171: 170: 166: 150: 143: 140: 127: 120: 117: 111: 107: 104: 102: 99: 97: 94: 92: 89: 87: 84: 83: 79: 77: 75: 69: 66: 64: 60: 56: 52: 47: 45: 41: 37: 32: 30: 26: 22: 738:Regeneration 590:South Africa 396:rejuvenation 386:nanomedicine 381:gene therapy 153:. Retrieved 142: 130:. Retrieved 119: 70: 67: 48: 33: 25:centenarians 20: 18: 725:Immortality 284:Centenarian 267:Gerontology 128:. Wired.com 91:Gerontology 51:epigenetics 36:Alzheimer's 857:Categories 708:by country 605:Tajikistan 570:Kazakhstan 428:by country 245:Senescence 112:References 822:Blue zone 580:Palestine 498:Australia 493:Argentina 219:Longevity 63:Tom Perls 27:) in the 703:verified 625:shortest 445:Americas 417:Lists of 367:Methods 80:See also 44:platelet 40:dementia 815:Related 686:Records 668:Oceania 630:longest 540:Germany 535:Finland 503:Belgium 472:Oceania 235:Old age 796:Klotho 713:living 658:Europe 648:Africa 610:Turkey 600:Sweden 585:Russia 575:Mexico 555:Israel 545:Greece 530:France 523:Cities 513:Canada 508:Brazil 467:Europe 440:Africa 227:Ageing 155:1 July 132:1 July 86:Ageing 31:area. 29:Boston 801:SIRT1 771:FOXO3 595:Spain 565:Japan 560:Italy 550:India 518:China 435:World 341:index 781:CETP 776:APOE 653:Asia 462:Asia 406:SENS 157:2010 134:2010 19:The 806:TNF 791:IL6 786:ACE 620:USA 859:: 615:UK 65:. 211:e 204:t 197:v 159:. 136:.

Index

centenarians
Boston
Alzheimer's
dementia
platelet
epigenetics
Harvard University
Boston University
Tom Perls
National Institute on Aging
Ageing
Gerontology
Okinawa Centenarian Study
Research into centenarians
Supercentenarian
"Genetic Secrets of Living to 100"
"New study of centenarians links certain genetic variations to a long lifespan"
New England Centenarian Study
Validation of Exceptional Longevity: Age Validation in the New England Centenarian Study
New England Supercentenarian Study
v
t
e
Longevity
Ageing
Old age
Longevity myths
Senescence
aging-associated diseases
degenerative diseases

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