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Neuroblastoma RAS viral oncogene homolog

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308: 2659: 2644: 2629: 285: 2974: 2674: 2359: 2344: 2329: 3004: 3019: 2989: 2959: 2944: 2809: 2299: 2284: 2269: 2194: 182: 207: 3034: 2224: 2389: 2554: 2539: 2524: 2509: 2494: 2434: 2419: 2929: 2869: 2914: 2899: 2854: 2884: 2839: 2404: 2209: 2764: 2704: 2254: 2824: 2779: 2734: 2749: 2314: 2794: 2479: 2464: 314: 213: 2689: 31: 2449: 2569: 2239: 2584: 2374: 2614: 2599: 2719: 3954: 1127:), an inactive pseudogene of each (c-Hras2 and c-Kras1) and the N-Ras gene. They differ significantly only in the C-terminal 40 amino acids. These Ras genes have GTP/GDP binding and GTPase activity, and their normal function may be as G-like regulatory proteins involved in the normal control of cell growth. 1135:(-I, I, II, III, IV, V, VI). The smaller 2 kb transcript contains the VIa exon, and the larger 4.3 kb transcript contains the VIb exon which is just a longer form of the VIa exon. Both transcripts encode identical proteins as they differ only the 3β€² untranslated region. 57: 2029:
Mitchell EL, Jones D, White GR, et al. (1995). "Determination of the gene order of the three loci CD2, NGFB, and NRAS at human chromosome band 1p13 and refinement of their localisation at the subband level by fluorescence in situ hybridisation".
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The N-Ras gene specifies two main transcripts of 2 kb and 4.3 kb. The difference between the two transcripts is a simple extension through the termination site of the 2 kb transcript. The N-Ras gene consists of seven
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Mutations which change amino acid residues 12, 13 or 61 activate the potential of N-ras to transform cultured cells and are implicated in a variety of human tumors e.g.
321: 220: 2403: 2667:: CRYSTALLOGRAPHIC STUDIES ON P21H-RAS USING SYNCHROTRON LAUE METHOD: IMPROVEMENT OF CRYSTAL QUALITY AND MONITORING OF THE GTPASE REACTION AT DIFFERENT TIME POINTS 2652:: CRYSTALLOGRAPHIC STUDIES ON P21H-RAS USING SYNCHROTRON LAUE METHOD: IMPROVEMENT OF CRYSTAL QUALITY AND MONITORING OF THE GTPASE REACTION AT DIFFERENT TIME POINTS 2637:: CRYSTALLOGRAPHIC STUDIES ON P21H-RAS USING SYNCHROTRON LAUE METHOD: IMPROVEMENT OF CRYSTAL QUALITY AND MONITORING OF THE GTPASE REACTION AT DIFFERENT TIME POINTS 1524:
Yuasa Y, Kamiyama T, Kato M, et al. (1990). "Transforming genes from familial adenomatous polyposis patient cells detected by a tumorigenicity assay".
1112:. It is mapped on chromosome 1, and it is activated in HL60, a promyelocytic leukemia line. The order of nearby genes is as follows: cenβ€”CD2β€”NGFBβ€”NRASβ€”tel. 1734:
Raybaud F, Noguchi T, Marics I, et al. (1988). "Detection of a low frequency of activated ras genes in human melanomas using a tumorigenicity assay".
2982:: REFINED CRYSTAL STRUCTURE OF THE TRIPHOSPHATE CONFORMATION OF H-RAS P21 AT 1.35 ANGSTROMS RESOLUTION: IMPLICATIONS FOR THE MECHANISM OF GTP HYDROLYSIS 2208: 803: 143: 784: 2763: 2703: 2253: 1713:
Nitta N, Ochiai M, Nagao M, Sugimura T (1987). "Amino-acid substitution at codon 13 of the N-ras oncogene in rectal cancer in a Japanese patient".
3067: 2823: 2778: 3297: 2733: 3995: 2748: 2173: 1243: 3266: 2313: 1225: 4014: 2793: 2478: 2463: 2682:: CRYSTAL STRUCTURES AT 2.2 ANGSTROMS RESOLUTION OF THE CATALYTIC DOMAINS OF NORMAL RAS PROTEIN AND AN ONCOGENIC MUTANT COMPLEXED WITH GSP 2688: 1005: 307: 3060: 1441:
van Elsas A, Scheibenbogen C, van der Minne C, et al. (1998). "UV-induced N-ras mutations are T-cell targets in human melanoma".
1012: 2367:: X-RAY CRYSTAL STRUCTURE ANALYSIS OF THE CATALYTIC DOMAIN OF THE ONCOGENE PRODUCT P21H-RAS COMPLEXED WITH CAGED GTP AND MANT DGPPNHP 2352:: X-RAY CRYSTAL STRUCTURE ANALYSIS OF THE CATALYTIC DOMAIN OF THE ONCOGENE PRODUCT P21H-RAS COMPLEXED WITH CAGED GTP AND MANT DGPPNHP 2337:: X-RAY CRYSTAL STRUCTURE ANALYSIS OF THE CATALYTIC DOMAIN OF THE ONCOGENE PRODUCT P21H-RAS COMPLEXED WITH CAGED GTP AND MANT DGPPNHP 1755:
Hirai H, Kobayashi Y, Mano H, et al. (1987). "A point mutation at codon 13 of the N-ras oncogene in myelodysplastic syndrome".
3012:: MOLECULAR SWITCH FOR SIGNAL TRANSDUCTION: STRUCTURAL DIFFERENCES BETWEEN ACTIVE AND INACTIVE FORMS OF PROTOONCOGENIC RAS PROTEINS 284: 2448: 1374: 2568: 2238: 3857: 3027:: THREE-DIMENSIONAL STRUCTURES OF H-RAS P21 MUTANTS: MOLECULAR BASIS FOR THEIR INABILITY TO FUNCTION AS SIGNAL SWITCH MOLECULES 2997:: THREE-DIMENSIONAL STRUCTURES OF H-RAS P21 MUTANTS: MOLECULAR BASIS FOR THEIR INABILITY TO FUNCTION AS SIGNAL SWITCH MOLECULES 2967:: THREE-DIMENSIONAL STRUCTURES OF H-RAS P21 MUTANTS: MOLECULAR BASIS FOR THEIR INABILITY TO FUNCTION AS SIGNAL SWITCH MOLECULES 2952:: THREE-DIMENSIONAL STRUCTURES OF H-RAS P21 MUTANTS: MOLECULAR BASIS FOR THEIR INABILITY TO FUNCTION AS SIGNAL SWITCH MOLECULES 2817:: THREE-DIMENSIONAL STRUCTURES OF H-RAS P21 MUTANTS: MOLECULAR BASIS FOR THEIR INABILITY TO FUNCTION AS SIGNAL SWITCH MOLECULES 2583: 1545:
Hancock JF, Magee AI, Childs JE, Marshall CJ (1989). "All ras proteins are polyisoprenylated but only some are palmitoylated".
1212: 1191: 3852: 2373: 2307:: THE SOLUTION STRUCTURE AND DYNAMICS OF RAS P21. GDP DETERMINED BY HETERONUCLEAR THREE AND FOUR DIMENSIONAL NMR SPECTROSCOPY 2292:: THE SOLUTION STRUCTURE AND DYNAMICS OF RAS P21. GDP DETERMINED BY HETERONUCLEAR THREE AND FOUR DIMENSIONAL NMR SPECTROSCOPY 2277:: THE SOLUTION STRUCTURE AND DYNAMICS OF RAS P21. GDP DETERMINED BY HETERONUCLEAR THREE AND FOUR DIMENSIONAL NMR SPECTROSCOPY 1208: 206: 181: 54: 3874: 1480:"Mapping the human amylase gene cluster on the proximal short arm of chromosome 1 using a highly informative (CA)n repeat" 2613: 1187: 3922: 3239: 1083: 123: 2202:: STRUKTUR UND GUANOSINTRIPHOSPHAT-HYDROLYSEMECHANISMUS DES C-TERMINAL VERKUERZTEN MENSCHLICHEN KREBSPROTEINS P21-H-RAS 1388:
Study Comparing the Efficacy of MEK162 Versus Dacarbazine in Unresectable or Metastatic NRAS Mutation-positive Melanoma
3844: 320: 219: 3988: 3042:: THREE-DIMENSIONAL STRUCTURES AND PROPERTIES OF A TRANSFORMING AND A NONTRANSFORMING GLYCINE-12 MUTANT OF P21H-RAS 2059:
Kodaki T, Woscholski R, Hallberg B, et al. (1995). "The activation of phosphatidylinositol 3-kinase by Ras".
3903: 3444: 3342: 3167: 3163: 3140: 3113: 3100: 3087: 2598: 2166: 313: 212: 2232:: THREE-DIMENSIONAL STRUCTURES AND PROPERTIES OF A TRANSFORMING AND A NONTRANSFORMING GLY-12 MUTANT OF P21-H-RAS 3458: 3153: 3118: 3091: 848: 131: 114:, ALPS4, CMNS, N-ras, NCMS, NRAS1, NS6, Neuroblastoma RAS viral oncogene homolog, NRAS proto-oncogene, GTPase 3828: 3791: 3130: 829: 2718: 2146: 1261:
Marshall CJ, Hall A, Weiss RA (September 1982). "A transforming gene present in human sarcoma cell lines".
4019: 3558: 3198: 2562:: Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS 2547:: Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS 2532:: Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS 2517:: Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS 1992:
Taparowsky E, Shimizu K, Goldfarb M, Wigler M (1983). "Structure and activation of the human N-ras gene".
2397:: C-H-RAS P21 PROTEIN MUTANT WITH THR 35 REPLACED BY SER (T35S) COMPLEXED WITH GUANOSINE-5'- TRIPHOSPHATE 3981: 3688: 3596: 1314:"Isolation and preliminary characterization of the transforming gene of a human neuroblastoma cell line" 1802:"Activation of an N-ras gene in acute myeloblastic leukemia through somatic mutation in the first exon" 1479: 2159: 1952: 1813: 1764: 1673: 1325: 1270: 195: 110: 3893: 943: 4024: 3908: 3474: 3052: 2502:: CRYSTAL STRUCTURE OF THE ACTIVE RAS PROTEIN COMPLEXED WITH THE RAS-INTERACTING DOMAIN OF RALGDS 2084: 2017: 1788: 1570: 1466: 1429: 1294: 155: 969: 939: 918: 3148: 2127: 2076: 2047: 2009: 1980: 1927: 1884: 1841: 1780: 1743: 1722: 1701: 1648: 1613: 1562: 1533: 1512: 1458: 1421: 1353: 1286: 103: 47: 3965: 3538: 3484: 3466: 3332: 3322: 3276: 2117: 2109: 2068: 2039: 2001: 1970: 1960: 1917: 1909: 1874: 1866: 1831: 1821: 1772: 1691: 1681: 1638: 1603: 1595: 1554: 1502: 1494: 1450: 1413: 1343: 1333: 1278: 400: 331: 275: 230: 3351: 2937:: Crystal structure analysis of a fluorescent form of H-Ras p21 in complex with R-caged GTP 2877:: CRYSTAL STRUCTURE ANALYSIS OF A FLUORESCENT FORM OF H-RAS P21 IN COMPLEX WITH S-CAGED GTP 3885: 3774: 3588: 3288: 3108: 375: 151: 2442:: H-RAS P21 PROTEIN MUTANT G12P, COMPLEXED WITH GUANOSINE-5'- TRIPHOSPHATE AND MANGANESE 2427:: H-RAS P21 PROTEIN MUTANT G12P, COMPLEXED WITH GUANOSINE-5'- TRIPHOSPHATE AND MAGNESIUM 1956: 1817: 1768: 1677: 1329: 1274: 3208: 2922:: CRYSTAL STRUCTURE ANALYSIS OF A FLUORESCENT FORM OF H-RAS P21 IN COMPLEX WITH GDP (2) 2907:: CRYSTAL STRUCTURE ANALYSIS OF A FLUORESCENT FORM OF H-RAS P21 IN COMPLEX WITH GTP (2) 2113: 2098:"Activation of phosphoinositide 3-kinase by interaction with Ras and by point mutation" 1913: 2862:: CRYSTAL STRUCTURE ANALYSIS OF A FLUORESCENT FORM OF H-RAS P21 IN COMPLEX WITH GPPNHP 2122: 2097: 2072: 1975: 1940: 1922: 1897: 1879: 1854: 1836: 1801: 1696: 1661: 1608: 1583: 1404:
McCormick F (1996). "Ras-related proteins in signal transduction and growth control".
1348: 1313: 718: 713: 708: 703: 698: 693: 688: 683: 678: 673: 668: 652: 647: 642: 637: 632: 627: 611: 606: 601: 596: 591: 30: 4008: 3752: 3362: 2005: 1898:"Mechanism of activation of an N-ras gene in the human fibrosarcoma cell line HT1080" 1558: 1498: 1454: 1109: 1097: 578: 2088: 2021: 1941:"Mechanism of activation of an N-ras oncogene of SW-1271 human lung carcinoma cells" 1574: 1470: 3737: 3710: 3639: 3632: 3615: 3610: 3584: 2892:: CRYSTAL STRUCTURE ANALYSIS OF A FLUORESCENT FORM OF H-RAS P21 IN COMPLEX WITH GTP 2847:: CRYSTAL STRUCTURE ANALYSIS OF A FLUORESCENT FORM OF H-RAS P21 IN COMPLEX WITH GDP 1792: 1433: 1298: 393: 172: 1643: 1626: 1387: 135: 159: 3833: 1248:
National Center for Biotechnology Information, U.S. National Library of Medicine
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National Center for Biotechnology Information, U.S. National Library of Medicine
1155: 1079: 2412:: Crystal Structure of the C-HA-RAS Protein Prepared by the Cell-Free Synthesis 476: 3818: 3507: 292: 189: 139: 1599: 3524: 3083: 1965: 1686: 1115:
The mammalian Ras gene family consists of the Harvey and Kirsten Ras genes (
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Rodriguez-Viciana P, Warne PH, Vanhaesebroeck B, et al. (1996).
1776: 1282: 1068: 1020: 770: 1375:"Entrez Gene: NRAS neuroblastoma RAS viral (v-ras) oncogene homolog" 1662:"Analysis of RAS oncogene mutations in human lymphoid malignancies" 3862: 3801: 3784: 3779: 3627: 3605: 3571: 3566: 3551: 3529: 3517: 3512: 3502: 3497: 3492: 3217: 3193: 2217:: HUMAN C-HA-RAS(1-171)(DOT)GDP, NMR, MINIMIZED AVERAGE STRUCTURE 733: 729: 3867: 3823: 3811: 3796: 3762: 3757: 3742: 3725: 3720: 3715: 3703: 3698: 3693: 3683: 3659: 3654: 3649: 3644: 3546: 1132: 1123: 1117: 1075: 127: 3056: 2772:: Crystal Structure of the GDP-bound form of the RasG60A mutant 2712:: H-RAS COMPLEXED WITH DIAMINOBENZOPHENONE-BETA,GAMMA-IMIDO-GTP 2262:: H-RAS COMPLEXED WITH DIAMINOBENZOPHENONE-BETA,GAMMA-IMIDO-GTP 2155: 3917: 3913: 2151: 2832:: STRUCTURE OF PLC EPSILON RAS ASSOCIATION DOMAIN WITH HRAS 2787:: Structure of the Q61G mutant of Ras in the GDP-bound form 1312:
Shimizu K, Goldfarb M, Perucho M, Wigler M (January 1983).
1078:. It was discovered by a small team of researchers led by 2742:: Crystal structure of the GppNHp-bound H-Ras G60A mutant 2757:: Crystal Structure of a ternary Ras:SOS:Ras*GDP complex 383: 3969: 2322:: STRUCTURE OF P21RAS IN COMPLEX WITH GPPNHP AT 100 K 719:
positive regulation of endothelial cell proliferation
548: 2802:: Crystal Structure of the GTP-bound form of RasQ61G 2487:: Crystal Structure of RasA59G in the GDP-bound Form 2472:: Crystal Structure of RasA59G in the GTP-bound form 674:
stimulatory C-type lectin receptor signaling pathway
3883: 3842: 3582: 3456: 3443: 3408: 3360: 3341: 3287: 3207: 3186: 3179: 3162: 3139: 3099: 1855:"Activation of N-ras in a human melanoma cell line" 983: 962: 932: 911: 2697:: STRUCTURE OF P21RAS IN COMPLEX WITH GTP AT 100 K 1204: 1202: 1200: 1183: 1181: 1179: 669:epidermal growth factor receptor signaling pathway 1660:Neri A, Knowles DM, Greco A, et al. (1988). 330: 229: 2147:GeneReviews/NCBI/NIH/UW entry on Noonan syndrome 1896:Brown R, Marshall CJ, Pennie SG, Hall A (1984). 1625:Hirai H, Tanaka S, Azuma M, et al. (1986). 1158:(MEK162) has had a phase III clinical trial for 1939:Yuasa Y, Gol RA, Chang A, et al. (1984). 1584:"Human N-ras: cDNA cloning and gene structure" 1209:GRCm38: Ensembl release 89: ENSMUSG00000027852 3989: 3068: 2167: 8: 1627:"Transforming genes in human leukemia cells" 1108:The N-ras proto-oncogene is a member of the 1188:GRCh38: Ensembl release 89: ENSG00000213281 3996: 3982: 3453: 3183: 3176: 3075: 3061: 3053: 2457:: Crystal structure of Ras-Bry2RBD complex 2174: 2160: 2152: 1096:, for its initial identification in human 744: 574: 371: 270: 167: 65: 2577:: H-Ras 166 in 50% 2,2,2 triflouroethanol 2247:: COMPLEX OF HUMAN H-RAS WITH HUMAN SOS-1 2121: 1974: 1964: 1921: 1878: 1835: 1825: 1695: 1685: 1642: 1607: 1506: 1347: 1337: 2592:: H-Ras 166 in Aqueous mother liquor, RT 1853:Padua RA, Barrass NC, Currie GA (1985). 1369: 1367: 2622:: H-RAS 166 in 60 % 1,6 hexanediol 2189: 1175: 2382:: RAS G12V - PI 3-KINASE GAMMA COMPLEX 1090:gene to be discovered, and was named 20: 689:Fc-epsilon receptor signaling pathway 335: 296: 291: 234: 193: 188: 7: 3950: 3948: 1800:Gambke C, Hall A, Moroni C (1985). 3968:. You can help Knowledge (XXG) by 2114:10.1002/j.1460-2075.1996.tb00602.x 1914:10.1002/j.1460-2075.1984.tb01970.x 980: 959: 929: 908: 884: 865: 839: 820: 794: 775: 597:protein-containing complex binding 553: 471: 409: 388: 14: 1478:Dracopoli NC, Meisler MH (1990). 1071:that in humans is encoded by the 3952: 3032: 3017: 3002: 2987: 2972: 2957: 2942: 2927: 2912: 2897: 2882: 2867: 2852: 2837: 2822: 2807: 2792: 2777: 2762: 2747: 2732: 2717: 2702: 2687: 2672: 2657: 2642: 2627: 2612: 2597: 2582: 2567: 2552: 2537: 2522: 2507: 2492: 2477: 2462: 2447: 2432: 2417: 2402: 2387: 2372: 2357: 2342: 2327: 2312: 2297: 2282: 2267: 2252: 2237: 2222: 2207: 2192: 1455:10.1097/00008390-199708001-00017 319: 312: 306: 283: 218: 211: 205: 180: 29: 694:Ras protein signal transduction 537:More reference expression data 1: 2073:10.1016/S0960-9822(00)00177-9 1644:10.1182/blood.V66.6.1371.1371 304: 203: 18:Protein-coding gene in humans 2006:10.1016/0092-8674(83)90390-2 1945:Proc. Natl. Acad. Sci. U.S.A 1806:Proc. Natl. Acad. Sci. U.S.A 1666:Proc. Natl. Acad. Sci. U.S.A 1559:10.1016/0092-8674(89)90054-8 1499:10.1016/0888-7543(90)90523-W 1086:in London. It was the third 1084:Institute of Cancer Research 4015:Genes on human chromosome 1 3845:Protein-synthesizing GTPase 4041: 3947: 2607:: H-Ras in 50% isopropanol 523:medial ganglionic eminence 3904:Guanylate-binding protein 3088:acid anhydride hydrolases 2187: 1244:"Mouse PubMed Reference:" 1226:"Human PubMed Reference:" 1051: 1046: 1042: 1035: 1019: 1013:Chr 3: 102.97 – 102.98 Mb 1000: 987: 966: 955: 936: 915: 904: 891: 887: 872: 868: 859: 846: 842: 827: 823: 814: 801: 797: 782: 778: 769: 754: 747: 743: 727: 653:tertiary granule membrane 577: 573: 561: 556: 547: 534: 483: 474: 429:epithelium of nasopharynx 421: 412: 382: 374: 370: 353: 340: 303: 282: 273: 269: 252: 239: 202: 179: 170: 166: 121: 118: 108: 101: 96: 73: 68: 51: 46: 41: 37: 28: 23: 3459:Heterotrimeric G protein 3154:Phosphoadenylylsulfatase 1582:Hall A, Brown R (1985). 1006:Chr 1: 114.7 – 114.72 Mb 714:neutrophil degranulation 3131:Thiamine-triphosphatase 1966:10.1073/pnas.81.12.3670 1687:10.1073/pnas.85.23.9268 709:ERBB2 signaling pathway 445:mucosa of sigmoid colon 3964:-related article is a 1600:10.1093/nar/13.14.5255 1418:10.1002/mrd.1080420419 337:3 F2.2|3 45.25 cM 3886:Polymerization motors 3597:Rho family of GTPases 2032:Cytogenet. Cell Genet 1827:10.1073/pnas.82.3.879 1339:10.1073/pnas.80.2.383 648:extracellular exosome 2727:: RAS-RASGAP COMPLEX 1449:(Suppl 2): S107–13. 298:Chromosome 3 (mouse) 196:Chromosome 1 (human) 69:List of PDB id codes 42:Available structures 3894:dynamin superfamily 1957:1984PNAS...81.3670Y 1871:10.1128/mcb.5.3.582 1818:1985PNAS...82..879G 1769:1987Natur.327..430H 1678:1988PNAS...85.9268N 1330:1983PNAS...80..383S 1275:1982Natur.299..171M 704:signal transduction 699:leukocyte migration 457:ganglionic eminence 449:germinal epithelium 425:gingival epithelium 1715:Jpn. J. Cancer Res 849:ENSMUSG00000027852 662:Biological process 621:Cellular component 592:nucleotide binding 585:Molecular function 519:epithelium of lens 3977: 3976: 3942: 3941: 3938: 3937: 3439: 3438: 3404: 3403: 3149:Adenylylsulfatase 3050: 3049: 2044:10.1159/000134028 1588:Nucleic Acids Res 1062: 1061: 1058: 1057: 1031: 1030: 996: 995: 977: 976: 951: 950: 926: 925: 900: 899: 881: 880: 855: 854: 836: 835: 810: 809: 791: 790: 739: 738: 569: 568: 565: 564: 543: 542: 530: 529: 499:lactiferous gland 468: 467: 366: 365: 265: 264: 92: 91: 88: 87: 52:Ortholog search: 4032: 3998: 3991: 3984: 3956: 3949: 3454: 3184: 3177: 3077: 3070: 3063: 3054: 3036: 3021: 3006: 2991: 2976: 2961: 2946: 2931: 2916: 2901: 2886: 2871: 2856: 2841: 2826: 2811: 2796: 2781: 2766: 2751: 2736: 2721: 2706: 2691: 2676: 2661: 2646: 2631: 2616: 2601: 2586: 2571: 2556: 2541: 2526: 2511: 2496: 2481: 2466: 2451: 2436: 2421: 2406: 2391: 2376: 2361: 2346: 2331: 2316: 2301: 2286: 2271: 2256: 2241: 2226: 2211: 2196: 2176: 2169: 2162: 2153: 2135: 2125: 2092: 2055: 2025: 1988: 1978: 1968: 1935: 1925: 1892: 1882: 1849: 1839: 1829: 1796: 1777:10.1038/327430a0 1751: 1730: 1709: 1699: 1689: 1656: 1646: 1621: 1611: 1578: 1541: 1520: 1510: 1484: 1474: 1437: 1406:Mol. Reprod. Dev 1390: 1385: 1379: 1378: 1371: 1362: 1361: 1351: 1341: 1309: 1303: 1302: 1283:10.1038/299171a0 1258: 1252: 1251: 1240: 1234: 1233: 1222: 1216: 1206: 1195: 1185: 1151:As a drug target 1044: 1043: 1015: 1008: 991: 981: 972: 960: 956:RefSeq (protein) 946: 930: 921: 909: 885: 866: 840: 821: 795: 776: 745: 575: 554: 539: 511:ventricular zone 491:genital tubercle 479: 477:Top expressed in 472: 433:secondary oocyte 417: 415:Top expressed in 410: 389: 372: 362: 349: 338: 323: 316: 310: 299: 287: 271: 261: 248: 237: 222: 215: 209: 198: 184: 168: 162: 160:NRAS - orthologs 113: 106: 83: 66: 60: 39: 38: 33: 21: 4040: 4039: 4035: 4034: 4033: 4031: 4030: 4029: 4005: 4004: 4003: 4002: 3945: 3943: 3934: 3879: 3838: 3589:Ras superfamily 3578: 3562: 3542: 3488: 3478: 3470: 3435: 3400: 3356: 3337: 3283: 3240:Plasma membrane 3203: 3158: 3135: 3109:Pyrophosphatase 3095: 3081: 3051: 3046: 3043: 3037: 3028: 3022: 3013: 3007: 2998: 2992: 2983: 2977: 2968: 2962: 2953: 2947: 2938: 2932: 2923: 2917: 2908: 2902: 2893: 2887: 2878: 2872: 2863: 2857: 2848: 2842: 2833: 2827: 2818: 2812: 2803: 2797: 2788: 2782: 2773: 2767: 2758: 2752: 2743: 2737: 2728: 2722: 2713: 2707: 2698: 2692: 2683: 2677: 2668: 2662: 2653: 2647: 2638: 2632: 2623: 2617: 2608: 2602: 2593: 2587: 2578: 2572: 2563: 2557: 2548: 2542: 2533: 2527: 2518: 2512: 2503: 2497: 2488: 2482: 2473: 2467: 2458: 2452: 2443: 2437: 2428: 2422: 2413: 2407: 2398: 2392: 2383: 2377: 2368: 2362: 2353: 2347: 2338: 2332: 2323: 2317: 2308: 2302: 2293: 2287: 2278: 2272: 2263: 2257: 2248: 2242: 2233: 2227: 2218: 2212: 2203: 2197: 2183: 2180: 2143: 2138: 2108:(10): 2442–51. 2095: 2058: 2028: 1991: 1938: 1895: 1859:Mol. Cell. Biol 1852: 1799: 1763:(6121): 430–2. 1754: 1733: 1712: 1672:(23): 9268–72. 1659: 1624: 1594:(14): 5255–68. 1581: 1544: 1523: 1482: 1477: 1440: 1403: 1399: 1397:Further reading 1394: 1393: 1386: 1382: 1373: 1372: 1365: 1311: 1310: 1306: 1269:(5879): 171–3. 1260: 1259: 1255: 1242: 1241: 1237: 1224: 1223: 1219: 1207: 1198: 1186: 1177: 1172: 1153: 1141: 1110:Ras gene family 1106: 1053:View/Edit Mouse 1048:View/Edit Human 1011: 1004: 1001:Location (UCSC) 989: 968: 942: 938: 917: 830:ENSG00000213281 723: 657: 643:plasma membrane 628:Golgi apparatus 616: 612:protein binding 607:GTPase activity 535: 526: 521: 517: 513: 509: 505: 501: 497: 493: 489: 475: 464: 461:parietal pleura 459: 455: 451: 447: 443: 441:mucosa of colon 439: 435: 431: 427: 413: 357: 344: 336: 326: 325: 324: 317: 297: 274:Gene location ( 256: 243: 235: 225: 224: 223: 216: 194: 171:Gene location ( 122: 109: 102: 75: 53: 19: 12: 11: 5: 4038: 4036: 4028: 4027: 4022: 4017: 4007: 4006: 4001: 4000: 3993: 3986: 3978: 3975: 3974: 3957: 3940: 3939: 3936: 3935: 3933: 3932: 3927: 3926: 3925: 3920: 3911: 3906: 3901: 3890: 3888: 3881: 3880: 3878: 3877: 3872: 3871: 3870: 3865: 3860: 3849: 3847: 3840: 3839: 3837: 3836: 3831: 3826: 3821: 3816: 3815: 3814: 3809: 3804: 3799: 3789: 3788: 3787: 3782: 3772: 3771: 3770: 3765: 3760: 3748: 3747: 3746: 3745: 3740: 3730: 3729: 3728: 3723: 3718: 3708: 3707: 3706: 3701: 3696: 3686: 3681: 3680: 3679: 3674: 3664: 3663: 3662: 3657: 3652: 3647: 3637: 3636: 3635: 3630: 3620: 3619: 3618: 3613: 3608: 3593: 3591: 3580: 3579: 3577: 3576: 3575: 3574: 3569: 3560: 3556: 3555: 3554: 3549: 3540: 3536: 3535: 3534: 3533: 3532: 3522: 3521: 3520: 3515: 3505: 3500: 3495: 3486: 3482: 3481: 3480: 3476: 3468: 3463: 3461: 3451: 3441: 3440: 3437: 3436: 3434: 3433: 3428: 3423: 3418: 3412: 3410: 3406: 3405: 3402: 3401: 3399: 3398: 3393: 3388: 3383: 3378: 3373: 3367: 3365: 3358: 3357: 3355: 3354: 3348: 3346: 3339: 3338: 3336: 3335: 3330: 3325: 3320: 3315: 3310: 3305: 3300: 3294: 3292: 3285: 3284: 3282: 3281: 3280: 3279: 3274: 3264: 3263: 3262: 3257: 3252: 3247: 3237: 3236: 3235: 3230: 3225: 3214: 3212: 3205: 3204: 3202: 3201: 3196: 3190: 3188: 3187:Cu++ (3.6.3.4) 3181: 3174: 3160: 3159: 3157: 3156: 3151: 3145: 3143: 3137: 3136: 3134: 3133: 3128: 3123: 3122: 3121: 3116: 3105: 3103: 3097: 3096: 3082: 3080: 3079: 3072: 3065: 3057: 3048: 3047: 3045: 3044: 3038: 3031: 3029: 3023: 3016: 3014: 3008: 3001: 2999: 2993: 2986: 2984: 2978: 2971: 2969: 2963: 2956: 2954: 2948: 2941: 2939: 2933: 2926: 2924: 2918: 2911: 2909: 2903: 2896: 2894: 2888: 2881: 2879: 2873: 2866: 2864: 2858: 2851: 2849: 2843: 2836: 2834: 2828: 2821: 2819: 2813: 2806: 2804: 2798: 2791: 2789: 2783: 2776: 2774: 2768: 2761: 2759: 2753: 2746: 2744: 2738: 2731: 2729: 2723: 2716: 2714: 2708: 2701: 2699: 2693: 2686: 2684: 2678: 2671: 2669: 2663: 2656: 2654: 2648: 2641: 2639: 2633: 2626: 2624: 2618: 2611: 2609: 2603: 2596: 2594: 2588: 2581: 2579: 2573: 2566: 2564: 2558: 2551: 2549: 2543: 2536: 2534: 2528: 2521: 2519: 2513: 2506: 2504: 2498: 2491: 2489: 2483: 2476: 2474: 2468: 2461: 2459: 2453: 2446: 2444: 2438: 2431: 2429: 2423: 2416: 2414: 2408: 2401: 2399: 2393: 2386: 2384: 2378: 2371: 2369: 2363: 2356: 2354: 2348: 2341: 2339: 2333: 2326: 2324: 2318: 2311: 2309: 2303: 2296: 2294: 2288: 2281: 2279: 2273: 2266: 2264: 2258: 2251: 2249: 2243: 2236: 2234: 2228: 2221: 2219: 2213: 2206: 2204: 2198: 2191: 2188: 2185: 2184: 2181: 2179: 2178: 2171: 2164: 2156: 2150: 2149: 2142: 2141:External links 2139: 2137: 2136: 2093: 2067:(9): 798–806. 2056: 2038:(3–4): 183–5. 2026: 1989: 1951:(12): 3670–4. 1936: 1893: 1850: 1797: 1752: 1731: 1710: 1657: 1622: 1579: 1553:(7): 1167–77. 1542: 1521: 1475: 1438: 1400: 1398: 1395: 1392: 1391: 1380: 1363: 1304: 1253: 1235: 1217: 1196: 1174: 1173: 1171: 1168: 1152: 1149: 1140: 1137: 1105: 1102: 1060: 1059: 1056: 1055: 1050: 1040: 1039: 1033: 1032: 1029: 1028: 1026: 1024: 1017: 1016: 1009: 1002: 998: 997: 994: 993: 985: 984: 978: 975: 974: 964: 963: 957: 953: 952: 949: 948: 934: 933: 927: 924: 923: 913: 912: 906: 902: 901: 898: 897: 889: 888: 882: 879: 878: 870: 869: 863: 857: 856: 853: 852: 844: 843: 837: 834: 833: 825: 824: 818: 812: 811: 808: 807: 799: 798: 792: 789: 788: 780: 779: 773: 767: 766: 761: 756: 752: 751: 741: 740: 737: 736: 725: 724: 722: 721: 716: 711: 706: 701: 696: 691: 686: 681: 676: 671: 665: 663: 659: 658: 656: 655: 650: 645: 640: 638:Golgi membrane 635: 630: 624: 622: 618: 617: 615: 614: 609: 604: 599: 594: 588: 586: 582: 581: 571: 570: 567: 566: 563: 562: 559: 558: 551: 545: 544: 541: 540: 532: 531: 528: 527: 525: 524: 520: 516: 515:corneal stroma 512: 508: 504: 500: 496: 492: 488: 487:tail of embryo 484: 481: 480: 469: 466: 465: 463: 462: 458: 454: 450: 446: 442: 438: 437:amniotic fluid 434: 430: 426: 422: 419: 418: 406: 405: 397: 386: 380: 379: 376:RNA expression 368: 367: 364: 363: 355: 351: 350: 342: 339: 334: 328: 327: 318: 311: 305: 301: 300: 295: 289: 288: 280: 279: 267: 266: 263: 262: 254: 250: 249: 241: 238: 233: 227: 226: 217: 210: 204: 200: 199: 192: 186: 185: 177: 176: 164: 163: 120: 116: 115: 107: 99: 98: 94: 93: 90: 89: 86: 85: 71: 70: 62: 61: 50: 44: 43: 35: 34: 26: 25: 17: 13: 10: 9: 6: 4: 3: 2: 4037: 4026: 4023: 4021: 4020:Protein stubs 4018: 4016: 4013: 4012: 4010: 3999: 3994: 3992: 3987: 3985: 3980: 3979: 3973: 3971: 3967: 3963: 3958: 3955: 3951: 3946: 3931: 3928: 3924: 3921: 3919: 3915: 3912: 3910: 3907: 3905: 3902: 3900: 3897: 3896: 3895: 3892: 3891: 3889: 3887: 3882: 3876: 3873: 3869: 3866: 3864: 3861: 3859: 3856: 3855: 3854: 3851: 3850: 3848: 3846: 3841: 3835: 3832: 3830: 3827: 3825: 3822: 3820: 3817: 3813: 3810: 3808: 3805: 3803: 3800: 3798: 3795: 3794: 3793: 3790: 3786: 3783: 3781: 3778: 3777: 3776: 3773: 3769: 3766: 3764: 3761: 3759: 3756: 3755: 3754: 3750: 3749: 3744: 3741: 3739: 3736: 3735: 3734: 3731: 3727: 3724: 3722: 3719: 3717: 3714: 3713: 3712: 3709: 3705: 3702: 3700: 3697: 3695: 3692: 3691: 3690: 3687: 3685: 3682: 3678: 3675: 3673: 3670: 3669: 3668: 3665: 3661: 3658: 3656: 3653: 3651: 3648: 3646: 3643: 3642: 3641: 3638: 3634: 3631: 3629: 3626: 3625: 3624: 3621: 3617: 3614: 3612: 3609: 3607: 3604: 3603: 3602: 3598: 3595: 3594: 3592: 3590: 3586: 3581: 3573: 3570: 3568: 3565: 3564: 3563: 3557: 3553: 3550: 3548: 3545: 3544: 3543: 3537: 3531: 3528: 3527: 3526: 3523: 3519: 3516: 3514: 3511: 3510: 3509: 3506: 3504: 3501: 3499: 3496: 3494: 3491: 3490: 3489: 3483: 3479: 3473: 3472: 3471: 3465: 3464: 3462: 3460: 3455: 3452: 3450: 3446: 3442: 3432: 3429: 3427: 3424: 3422: 3419: 3417: 3414: 3413: 3411: 3407: 3397: 3394: 3392: 3389: 3387: 3384: 3382: 3379: 3377: 3374: 3372: 3369: 3368: 3366: 3364: 3363:P-type ATPase 3359: 3353: 3350: 3349: 3347: 3344: 3340: 3334: 3331: 3329: 3326: 3324: 3321: 3319: 3316: 3314: 3311: 3309: 3306: 3304: 3301: 3299: 3296: 3295: 3293: 3290: 3286: 3278: 3275: 3273: 3270: 3269: 3268: 3265: 3261: 3258: 3256: 3253: 3251: 3248: 3246: 3243: 3242: 3241: 3238: 3234: 3231: 3229: 3226: 3224: 3221: 3220: 3219: 3216: 3215: 3213: 3210: 3206: 3200: 3197: 3195: 3192: 3191: 3189: 3185: 3182: 3178: 3175: 3173: 3169: 3165: 3161: 3155: 3152: 3150: 3147: 3146: 3144: 3142: 3138: 3132: 3129: 3127: 3124: 3120: 3117: 3115: 3112: 3111: 3110: 3107: 3106: 3104: 3102: 3098: 3093: 3089: 3085: 3078: 3073: 3071: 3066: 3064: 3059: 3058: 3055: 3041: 3035: 3030: 3026: 3020: 3015: 3011: 3005: 3000: 2996: 2990: 2985: 2981: 2975: 2970: 2966: 2960: 2955: 2951: 2945: 2940: 2936: 2930: 2925: 2921: 2915: 2910: 2906: 2900: 2895: 2891: 2885: 2880: 2876: 2870: 2865: 2861: 2855: 2850: 2846: 2840: 2835: 2831: 2825: 2820: 2816: 2810: 2805: 2801: 2795: 2790: 2786: 2780: 2775: 2771: 2765: 2760: 2756: 2750: 2745: 2741: 2735: 2730: 2726: 2720: 2715: 2711: 2705: 2700: 2696: 2690: 2685: 2681: 2675: 2670: 2666: 2660: 2655: 2651: 2645: 2640: 2636: 2630: 2625: 2621: 2615: 2610: 2606: 2600: 2595: 2591: 2585: 2580: 2576: 2570: 2565: 2561: 2555: 2550: 2546: 2540: 2535: 2531: 2525: 2520: 2516: 2510: 2505: 2501: 2495: 2490: 2486: 2480: 2475: 2471: 2465: 2460: 2456: 2450: 2445: 2441: 2435: 2430: 2426: 2420: 2415: 2411: 2405: 2400: 2396: 2390: 2385: 2381: 2375: 2370: 2366: 2360: 2355: 2351: 2345: 2340: 2336: 2330: 2325: 2321: 2315: 2310: 2306: 2300: 2295: 2291: 2285: 2280: 2276: 2270: 2265: 2261: 2255: 2250: 2246: 2240: 2235: 2231: 2225: 2220: 2216: 2210: 2205: 2201: 2195: 2190: 2186: 2177: 2172: 2170: 2165: 2163: 2158: 2157: 2154: 2148: 2145: 2144: 2140: 2133: 2129: 2124: 2119: 2115: 2111: 2107: 2103: 2099: 2094: 2090: 2086: 2082: 2078: 2074: 2070: 2066: 2062: 2057: 2053: 2049: 2045: 2041: 2037: 2033: 2027: 2023: 2019: 2015: 2011: 2007: 2003: 1999: 1995: 1990: 1986: 1982: 1977: 1972: 1967: 1962: 1958: 1954: 1950: 1946: 1942: 1937: 1933: 1929: 1924: 1919: 1915: 1911: 1908:(6): 1321–6. 1907: 1903: 1899: 1894: 1890: 1886: 1881: 1876: 1872: 1868: 1864: 1860: 1856: 1851: 1847: 1843: 1838: 1833: 1828: 1823: 1819: 1815: 1812:(3): 879–82. 1811: 1807: 1803: 1798: 1794: 1790: 1786: 1782: 1778: 1774: 1770: 1766: 1762: 1758: 1753: 1749: 1745: 1741: 1737: 1732: 1728: 1724: 1720: 1716: 1711: 1707: 1703: 1698: 1693: 1688: 1683: 1679: 1675: 1671: 1667: 1663: 1658: 1654: 1650: 1645: 1640: 1637:(6): 1371–8. 1636: 1632: 1628: 1623: 1619: 1615: 1610: 1605: 1601: 1597: 1593: 1589: 1585: 1580: 1576: 1572: 1568: 1564: 1560: 1556: 1552: 1548: 1543: 1539: 1535: 1532:(4): 589–96. 1531: 1527: 1522: 1518: 1514: 1509: 1508:2027.42/28584 1504: 1500: 1496: 1493:(1): 97–102. 1492: 1488: 1481: 1476: 1472: 1468: 1464: 1460: 1456: 1452: 1448: 1444: 1439: 1435: 1431: 1427: 1423: 1419: 1415: 1411: 1407: 1402: 1401: 1396: 1389: 1384: 1381: 1376: 1370: 1368: 1364: 1359: 1355: 1350: 1345: 1340: 1335: 1331: 1327: 1323: 1319: 1315: 1308: 1305: 1300: 1296: 1292: 1288: 1284: 1280: 1276: 1272: 1268: 1264: 1257: 1254: 1249: 1245: 1239: 1236: 1231: 1227: 1221: 1218: 1214: 1210: 1205: 1203: 1201: 1197: 1193: 1189: 1184: 1182: 1180: 1176: 1169: 1167: 1165: 1161: 1157: 1150: 1148: 1146: 1138: 1136: 1134: 1128: 1126: 1125: 1120: 1119: 1113: 1111: 1103: 1101: 1099: 1098:neuroblastoma 1095: 1094: 1089: 1085: 1081: 1077: 1074: 1070: 1066: 1054: 1049: 1045: 1041: 1038: 1034: 1027: 1025: 1022: 1018: 1014: 1010: 1007: 1003: 999: 992: 986: 982: 979: 973: 971: 965: 961: 958: 954: 947: 945: 941: 935: 931: 928: 922: 920: 914: 910: 907: 905:RefSeq (mRNA) 903: 896: 895: 890: 886: 883: 877: 876: 871: 867: 864: 862: 858: 851: 850: 845: 841: 838: 832: 831: 826: 822: 819: 817: 813: 806: 805: 800: 796: 793: 787: 786: 781: 777: 774: 772: 768: 765: 762: 760: 757: 753: 750: 746: 742: 735: 731: 726: 720: 717: 715: 712: 710: 707: 705: 702: 700: 697: 695: 692: 690: 687: 685: 684:axon guidance 682: 680: 677: 675: 672: 670: 667: 666: 664: 661: 660: 654: 651: 649: 646: 644: 641: 639: 636: 634: 631: 629: 626: 625: 623: 620: 619: 613: 610: 608: 605: 603: 600: 598: 595: 593: 590: 589: 587: 584: 583: 580: 579:Gene ontology 576: 572: 560: 555: 552: 550: 546: 538: 533: 522: 518: 514: 510: 506: 503:sciatic nerve 502: 498: 494: 490: 486: 485: 482: 478: 473: 470: 460: 456: 453:skin of thigh 452: 448: 444: 440: 436: 432: 428: 424: 423: 420: 416: 411: 408: 407: 404: 402: 398: 396: 395: 391: 390: 387: 385: 381: 377: 373: 369: 361: 356: 352: 348: 343: 333: 329: 322: 315: 309: 302: 294: 290: 286: 281: 277: 272: 268: 260: 255: 251: 247: 242: 232: 228: 221: 214: 208: 201: 197: 191: 187: 183: 178: 174: 169: 165: 161: 157: 153: 149: 145: 141: 137: 133: 129: 125: 117: 112: 105: 100: 95: 84: 82: 78: 72: 67: 64: 63: 59: 56: 49: 45: 40: 36: 32: 27: 22: 16: 3970:expanding it 3959: 3944: 3767: 3732: 3666: 3622: 3600: 3585:Small GTPase 3199:Wilson/ATP7B 3194:Menkes/ATP7A 3039: 3024: 3009: 2994: 2979: 2964: 2949: 2934: 2919: 2904: 2889: 2874: 2859: 2844: 2829: 2814: 2799: 2784: 2769: 2754: 2739: 2724: 2709: 2694: 2679: 2664: 2649: 2634: 2619: 2604: 2589: 2574: 2559: 2544: 2529: 2514: 2499: 2484: 2469: 2454: 2439: 2424: 2409: 2394: 2379: 2364: 2349: 2334: 2319: 2304: 2289: 2274: 2259: 2244: 2229: 2214: 2199: 2105: 2101: 2064: 2060: 2035: 2031: 2000:(2): 581–6. 1997: 1993: 1948: 1944: 1905: 1901: 1865:(3): 582–5. 1862: 1858: 1809: 1805: 1760: 1756: 1742:(4): 950–3. 1739: 1735: 1718: 1714: 1669: 1665: 1634: 1630: 1591: 1587: 1550: 1546: 1529: 1525: 1490: 1486: 1446: 1443:Melanoma Res 1442: 1412:(4): 500–6. 1409: 1405: 1383: 1324:(2): 383–7. 1321: 1317: 1307: 1266: 1262: 1256: 1247: 1238: 1229: 1220: 1159: 1154: 1142: 1129: 1122: 1116: 1114: 1107: 1092: 1091: 1087: 1072: 1064: 1063: 988: 967: 944:NM_001368638 937: 916: 892: 873: 847: 828: 802: 783: 763: 758: 679:MAPK cascade 399: 392: 358:102,975,230 345:102,965,601 257:114,716,771 244:114,704,469 119:External IDs 74: 15: 3909:Mitofusin-1 3884:3.6.5.5-6: 3853:Prokaryotic 2182:PDB gallery 1721:(1): 21–6. 1162:Q61 mutant 1156:Binimetinib 1080:Robin Weiss 602:GTP binding 97:Identifiers 4009:Categories 3875:Eukaryotic 3508:Transducin 3345:(3.6.3.10) 3084:Hydrolases 2061:Curr. Biol 1736:Cancer Res 1215:, May 2017 1194:, May 2017 1170:References 403:(ortholog) 140:HomoloGene 4025:Oncogenes 3843:3.6.5.3: 3583:3.6.5.2: 3525:Gustducin 3457:3.6.5.1: 3291:(3.6.3.9) 3211:(3.6.3.8) 3114:Inorganic 1139:Mutations 970:NP_002515 940:NM_010937 919:NM_002524 749:Orthologs 148:GeneCards 3119:Thiamine 2089:20836474 2022:39787991 1575:19292550 1526:Oncogene 1487:Genomics 1471:19219505 1211:– 1190:– 1164:melanoma 1145:melanoma 1104:Function 1037:Wikidata 728:Sources: 633:membrane 507:yolk sac 3962:protein 3930:Tubulin 3899:Dynamin 3751:other: 3431:Katanin 3421:Kinesin 3396:ATP13A3 3391:ATP13A2 3126:Apyrase 2132:8665852 2081:7820549 2052:7789166 2014:6616621 1985:6587382 1953:Bibcode 1932:6086315 1889:3887133 1846:3856237 1814:Bibcode 1793:4270769 1785:3295562 1765:Bibcode 1748:3276402 1727:3102434 1706:3057505 1674:Bibcode 1653:2998510 1618:2991860 1567:2661017 1538:1970154 1517:1692298 1463:9578425 1434:6507743 1426:8607982 1358:6300838 1326:Bibcode 1299:4342747 1291:6287287 1271:Bibcode 1213:Ensembl 1192:Ensembl 1100:cells. 1082:at the 861:UniProt 816:Ensembl 755:Species 734:QuickGO 378:pattern 104:Aliases 3807:ARL13B 3667:RhoBTB 3561:Ξ±12/13 3449:GTPase 3426:Myosin 3416:Dynein 3386:ATP12A 3381:ATP11B 3376:ATP10A 3371:ATP8B1 3361:Other 3333:ATP1B4 3328:ATP1B3 3323:ATP1B2 3318:ATP1B1 3313:ATP1A4 3308:ATP1A3 3303:ATP1A2 3298:ATP1A1 3289:Na+/K+ 3277:ATP2C2 3272:ATP2C1 3260:ATP2B4 3255:ATP2B3 3250:ATP2B2 3245:ATP2B1 3233:ATP2A3 3228:ATP2A2 3223:ATP2A1 3172:ATPase 2130:  2123:450176 2120:  2102:EMBO J 2087:  2079:  2050:  2020:  2012:  1983:  1976:345280 1973:  1930:  1923:557516 1920:  1902:EMBO J 1887:  1880:366752 1877:  1844:  1837:397150 1834:  1791:  1783:  1757:Nature 1746:  1725:  1704:  1697:282720 1694:  1651:  1616:  1609:321863 1606:  1573:  1565:  1536:  1515:  1469:  1461:  1432:  1424:  1356:  1349:393381 1346:  1297:  1289:  1263:Nature 1069:enzyme 1067:is an 1023:search 1021:PubMed 894:P08556 875:P01111 771:Entrez 549:BioGPS 495:zygote 236:1p13.2 128:164790 3960:This 3863:EF-Tu 3802:SAR1B 3785:RAB27 3780:RAB23 3733:RhoDF 3623:RhoUV 3606:CDC42 3601:Cdc42 3587:> 3572:GNA13 3567:GNA12 3552:GNA11 3541:Ξ±q/11 3530:GNAT3 3518:GNAT2 3513:GNAT1 3503:GNAI3 3498:GNAI2 3493:GNAI1 3445:3.6.5 3409:3.6.4 3352:ATP4A 3343:H+/K+ 3218:SERCA 3180:3.6.3 3164:3.6.3 3141:3.6.2 3101:3.6.1 2085:S2CID 2018:S2CID 1789:S2CID 1631:Blood 1571:S2CID 1483:(PDF) 1467:S2CID 1430:S2CID 1295:S2CID 1133:exons 804:18176 764:Mouse 759:Human 730:Amigo 401:Mouse 394:Human 341:Start 276:Mouse 240:Start 173:Human 144:55661 136:97376 3966:stub 3923:OPA1 3916:and 3868:EF-G 3858:IF-2 3824:Rheb 3812:ARL6 3797:ARF6 3768:NRAS 3763:KRAS 3758:HRAS 3743:RhoD 3738:RhoF 3684:RhoH 3660:RhoG 3645:Rac1 3633:RhoV 3628:RhoU 3611:TC10 3547:GNAQ 3267:SPCA 3094:3.6) 3040:821p 3025:721p 3010:6q21 2995:621p 2980:5p21 2965:521p 2950:421p 2935:2evw 2920:2cld 2905:2clc 2890:2cl7 2875:2cl6 2860:2cl0 2845:2ce2 2830:2c5l 2815:221p 2800:1zw6 2785:1zvq 2770:1xj0 2755:1xd2 2740:1xcm 2725:1wq1 2710:1rvd 2695:1qra 2680:1q21 2665:1pll 2650:1plk 2635:1plj 2620:1p2v 2605:1p2u 2590:1p2t 2575:1p2s 2560:1nvx 2545:1nvw 2530:1nvv 2515:1nvu 2500:1lfd 2485:1lf5 2470:1lf0 2455:1k8r 2440:1jai 2425:1jah 2410:1ioz 2395:1iaq 2380:1he8 2365:1gnr 2350:1gnq 2335:1gnp 2320:1ctq 2305:1crr 2290:1crq 2275:1crp 2260:1clu 2245:1bkd 2230:1agp 2215:1aa9 2200:121p 2128:PMID 2077:PMID 2048:PMID 2010:PMID 1994:Cell 1981:PMID 1928:PMID 1885:PMID 1842:PMID 1781:PMID 1744:PMID 1723:PMID 1702:PMID 1649:PMID 1614:PMID 1563:PMID 1547:Cell 1534:PMID 1513:PMID 1459:PMID 1422:PMID 1354:PMID 1318:PNAS 1287:PMID 1160:NRAS 1124:KRAS 1121:and 1118:HRAS 1093:NRAS 1076:gene 1073:NRAS 1065:NRAS 785:4893 384:Bgee 332:Band 293:Chr. 231:Band 190:Chr. 152:NRAS 124:OMIM 111:NRAS 81:2N9C 77:3CON 58:RCSB 55:PDBe 24:NRAS 3918:MX2 3914:MX1 3834:RGK 3829:Rap 3819:Ran 3792:Arf 3775:Rab 3753:Ras 3711:Rnd 3689:Rho 3640:Rac 3616:TCL 3477:olf 3209:Ca+ 2118:PMC 2110:doi 2069:doi 2040:doi 2002:doi 1971:PMC 1961:doi 1918:PMC 1910:doi 1875:PMC 1867:doi 1832:PMC 1822:doi 1773:doi 1761:327 1692:PMC 1682:doi 1639:doi 1604:PMC 1596:doi 1555:doi 1503:hdl 1495:doi 1451:doi 1414:doi 1344:PMC 1334:doi 1279:doi 1267:299 1088:RAS 990:n/a 557:n/a 354:End 253:End 156:OMA 132:MGI 48:PDB 4011:: 3599:: 3487:Ξ±i 3469:Ξ±s 3447:: 3170:: 3092:EC 3086:: 2126:. 2116:. 2106:15 2104:. 2100:. 2083:. 2075:. 2063:. 2046:. 2036:70 2034:. 2016:. 2008:. 1998:34 1996:. 1979:. 1969:. 1959:. 1949:81 1947:. 1943:. 1926:. 1916:. 1904:. 1900:. 1883:. 1873:. 1861:. 1857:. 1840:. 1830:. 1820:. 1810:82 1808:. 1804:. 1787:. 1779:. 1771:. 1759:. 1740:48 1738:. 1719:78 1717:. 1700:. 1690:. 1680:. 1670:85 1668:. 1664:. 1647:. 1635:66 1633:. 1629:. 1612:. 1602:. 1592:13 1590:. 1586:. 1569:. 1561:. 1551:57 1549:. 1528:. 1511:. 1501:. 1489:. 1485:. 1465:. 1457:. 1445:. 1428:. 1420:. 1410:42 1408:. 1366:^ 1352:. 1342:. 1332:. 1322:80 1320:. 1316:. 1293:. 1285:. 1277:. 1265:. 1246:. 1228:. 1199:^ 1178:^ 1166:. 1147:. 732:/ 360:bp 347:bp 259:bp 246:bp 154:; 150:: 146:; 142:: 138:; 134:: 130:; 126:: 79:, 3997:e 3990:t 3983:v 3972:. 3726:3 3721:2 3716:1 3704:C 3699:B 3694:A 3677:2 3672:1 3655:3 3650:2 3559:G 3539:G 3485:G 3475:G 3467:G 3168:4 3166:- 3090:( 3076:e 3069:t 3062:v 2175:e 2168:t 2161:v 2134:. 2112:: 2091:. 2071:: 2065:4 2054:. 2042:: 2024:. 2004:: 1987:. 1963:: 1955:: 1934:. 1912:: 1906:3 1891:. 1869:: 1863:5 1848:. 1824:: 1816:: 1795:. 1775:: 1767:: 1750:. 1729:. 1708:. 1684:: 1676:: 1655:. 1641:: 1620:. 1598:: 1577:. 1557:: 1540:. 1530:5 1519:. 1505:: 1497:: 1491:7 1473:. 1453:: 1447:7 1436:. 1416:: 1377:. 1360:. 1336:: 1328:: 1301:. 1281:: 1273:: 1250:. 1232:. 278:) 175:) 158::

Index


PDB
PDBe
RCSB
3CON
2N9C
Aliases
NRAS
OMIM
164790
MGI
97376
HomoloGene
55661
GeneCards
NRAS
OMA
NRAS - orthologs
Human
Chromosome 1 (human)
Chr.
Chromosome 1 (human)
Chromosome 1 (human)
Genomic location for NRAS
Genomic location for NRAS
Band
bp
bp
Mouse
Chromosome 3 (mouse)

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