Knowledge (XXG)

Nicola Dalbeth

Source šŸ“

226:. (2012) This was the second part of a task that a group of researchers including Dalbeth that was asked to complete for the American College of Rheumatology (ACR) to develop nonpharmacologic and pharmacologic guidelines for safe and effective treatments in gout. After completing a review of the literature and conducting formal group assessments, they completed the "first ACR guidelines for the therapy and anti-inflammatory prophylaxis of acute gout attacks." 186: 220:. The evidence suggested that further studies would be helpful, concluding it was "hoped that publication of these guidelines, along with effective patient education in gout treatments, and the objectives and safety issues of management, will improve patient adherence, quality of care, and outcomes in management of gout." 133:
challenges widely-held beliefs about the risk factors and causes of the condition. Her work confirms that there are many factors determining gout, but concludes that most people, including some health professionals, view it as a "self-inflicted condition for which dietary solutions are most important
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That there are disparities in gout care in Indigenous people is without a doubt. The challenge for healthcare providers in every country, including Aotearoa New Zealand, is to authentically partner with Indigenous people to develop culturally appropriate, acceptable and effective systems to overcome
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Dalbeth is a principal investigator in the Auckland Bone and Joint Research Group, and a member of the medical committee for the Auckland Medical Research Foundation. She is co-chair of the Calcium pyrophosphate deposition (CPPD) Working Group, (OMERACT), and was part of the Core Leadership Team for
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A paper published in 2021 summarising research that Dalbeth had been involved in, concluded that there was the existence of population-amplified genetic variants conferring risk of gout in Polynesian populations. Dalbeth collaborated on a 2020 study that did a content analysis of visual images used
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in educational resources about Gout and from the data, the researchers concluded: "Key concepts about gout and treatment are underrepresented in the images used in educational resources for patients. A large proportion of the images do not convey useful information about gout or its management."
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A review of the effectiveness of interventions to improve uptake of urate-lowering therapy (URL) in patients with gout in 2020 noted, in the paper co-edited by Dalbeth, that globally low numbers of patients were being treated with ULT was low. The researchers concluded for this to improve there
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In 2021 Dalbeth won the top research award of the medical faculty of the University of Auckland, the Gluckman Medal, for distinguished contribution to research on gout. Professor John Fraser, the Dean of the Faculty of Medical and Health Science said
113:, Dalbeth returned to Auckland in 2005 and to take up dual appointments as professor at the University of Auckland and at Auckland District Health Board. In 2016, she was chair of The Health & Safety Commission's expert advisory group on gout. 150:
may be because they involve the most patient engagement, empowering patients to share decisions about their care, which increases the likelihood that they will make the sustained behavioural changes required to take long-term medication."
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Nicola's research has contributed to dispelling the many myths about gout and her findings have been instrumental in improving the treatments available for patients with this debilitating disease."
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In 2021 in response to data that showed gout disproportionally affects Māori, Dalbeth co-authored a research paper that reviewed inequities in health due to gout management. The paper concluded:
232:. (2015) Dalbeth was a member of an international group of researchers that did a review of the literature on advanced imaging of gout that provided data to develop the classification criteria. 117:
2020 American College of Rheumatology Guideline for the Management of Gout. Dalbeth is an Associate Investigator at the Maurice Wilkins Centre for Molecular Biodiscovery, and a Consultant for
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Dalbeth completed undergraduate medical training at Otago Medical School in 1995 and rheumatology advanced training in Auckland in 2002. After postgraduate research training at the
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disparities and enable a pathway to health equity and beyond for people with gout. To fail to do so is acceptance of the status quo, and is, by definition, structural racism.
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and laboratory research programmes and holds dual appointments as a full professor at the University of Auckland and as a consultant for the Auckland District Health Board.
354: 933:"2012 American College of Rheumatology guidelines for management of gout. Part 1: Systematic nonpharmacologic and pharmacologic therapeutic approaches to hyperuricemia" 528: 389: 210:
American College of Rheumatology guidelines for management of gout. Part 1: systematic nonpharmacologic and pharmacologic therapeutic approaches to hyperuricemia.
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needed to be a greater patient understanding of the process to get adherence to the therapy, and that nurse-led interventions were often the most effective,
164: 906: 1251: 993:"2012 American College of Rheumatology guidelines for management of gout. Part 2: Therapy and antiinflammatory prophylaxis of acute gouty arthritis" 212:(2012) This is part 1 of research by a team including Dalbeth, to develop recommendations for effective treatment of gout specifically focusing on 167:
in 2019, an "honour that recognises distinction in research, scholarship or the advancement of knowledge at the highest international standards."
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American College of Rheumatology guidelines for management of gout. Part 2: therapy and antiinflammatory prophylaxis of acute gouty arthritis
1194:"Dose Adjustment of Allopurinol According to Creatinine Clearance Does not Provide Adequate Control of Hyperuricemia in Patients with GoutD" 1266: 1236: 790: 258:
Dose adjustment of allopurinol according to creatinine clearance does not provide adequate control of hyperuricemia in patients with gout.
1108: 1241: 1261: 1208: 1060:"2015 Gout classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative" 230:
2015 Gout classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative
763:"Aotearoa New Zealand Māori and Pacific population-specific gout risk variants: CLNK is a separate risk gene at the SLC2A9 locus" 739: 272:......further work is required to clarify the safety and efficacy of allopurinol dose escalation, particularly in patients with 332: 519: 118: 1130:"CD56brightNK Cells Are Enriched at Inflammatory Sites and Can Engage with Monocytes in a Reciprocal Program of Activation" 236:
CD56bright NK cells are enriched at inflammatory sites and can engage with monocytes in a reciprocal program of activation.
1175: 265: 385: 446: 553: 814:"Not Every Picture Tells a Story: A Content Analysis of Visual Images in Patient Educational Resources About Gout" 898: 110: 1231: 67: 247: 992: 694:"Interventions to improve uptake of urate-lowering therapy in patients with gout: a systematic review" 583: 251: 106: 294: 42: 195: 1167: 841: 812:
Krasnoryadtseva, Alina; Derksen, Christina; Dalbeth, Nicola; Petrie, Keith J. (1 December 2020).
782: 762: 246:, suggesting that "this interaction is important in the maintenance of inflammation in chronic 1159: 1151: 1100: 1082: 1059: 1033: 1015: 970: 952: 833: 731: 713: 674: 645:"Inequities in people with gout: a focus on Māori (Indigenous People) of Aotearoa New Zealand" 501: 238:(2004) This paper, co-authored by Dalbeth, recorded the findings of research into the role of 94: 134:
and effective, despite no clinical trial data in people with gout to support this approach."
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at sites of inflammation. The study showed that NK cells are capable of interacting with
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Gill, Iqbal; Dalbeth, Nicola; 'Ofanoa, Malakai; Goodyear-Smith, Felicity (7 July 2020).
191: 1095: 1028: 965: 932: 726: 669: 644: 496: 469: 1225: 845: 786: 693: 470:"OMERACT: An international initiative to improve outcome measurement in rheumatology" 269: 1171: 1078: 1058:
Neogi, Tuhina; Jansen, Tim L Th A; Dalbeth, Nicola; et al. (9 September 2015).
614:"Nicola Dalbeth and Keith J Petrie: It's time to change the name of gout - The BMJ" 324: 239: 86: 1146: 261: 1129: 709: 660: 640: 1155: 1086: 1019: 956: 897:
Health and medicine, Faculty of Medical and Health Sciences (27 April 2021).
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2020 American College of Rheumatology Guideline for the Management of Gout
899:"World-leading gout expert Professor Nicola Dalbeth wins Gluckman Medal" 872:"Researchers and scholars at the top of their fields elected as Fellows" 1011: 948: 931:
Khanna, Dinesh; Fitzgerald, John D.; et al. (28 September 2012).
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whose research focuses on understanding the impact and mechanisms of
268:......investigated whether such dosing provides adequate control of 991:
Khanna, Dinesh; Khanna, Puja P.; et al. (28 September 2012).
443:"About the Calcium pyrophosphate deposition (CPPD) Working Group" 704:(3). Royal College of General Practitioners: bjgpopen20X101051. 130: 90: 926: 924: 1140:(10). The American Association of Immunologists: 6418ā€“6426. 355:"Men, Māori and Pacific people need better gout medication" 1187: 1185: 986: 984: 260:(2006) After examining the guidelines stating that " 63: 55: 38: 30: 23: 1128:Dalbeth, Nicola; et al. (4 November 2004). 590:. Auckland District Health Board Te Toka Tumai. 525:(Supplementary Appendix 2: Panel/Teams Involved) 468:Tugwell, Peter; et al. (26 November 2007). 874:. Royal Society Te Apārangi. 21 November 2019. 649:Therapeutic Advances in Musculoskeletal Disease 8: 1247:Academic staff of the University of Auckland 1123: 1121: 295:"Professor Nicola Dalbeth, MBChB, MD, FRACP" 59:Research into diagnosis and management gout 1257:Fellows of the Royal Society of New Zealand 129:Much of Dalbeth's research that focuses on 165:Fellow of the Royal Society of New Zealand 20: 16:Rheumatologist and academic in New Zealand 1145: 1094: 1027: 964: 725: 668: 495: 485: 761:Ji, Aichang; et al. (1 July 2021). 384:Faculty of Medical and Health Sciences. 286: 264:doses should be adjusted according to 1192:Dalbeth, Nicola; et al. (2006). 878:from the original on 28 December 2019 852:from the original on 28 December 2019 554:"Our People: Associate Investigators" 7: 584:"Auckland DHB Rheumatology Services" 416:Auckland Medical Research Foundation 392:from the original on 4 February 2022 1047:from the original on 28 March 2016. 639:Te Karu, Leanne; Dalbeth, Nicoloa; 1214:from the original on 8 April 2022. 909:from the original on 28 April 2021 742:from the original on 18 March 2022 14: 1178:from the original on 26 May 2021. 1114:from the original on 6 July 2017. 793:from the original on 14 July 2021 620:from the original on 12 July 2021 594:from the original on 6 March 2022 564:from the original on 13 July 2021 534:from the original on 14 July 2021 449:from the original on 13 July 2021 422:from the original on 8 April 2022 365:from the original on 8 April 2022 335:from the original on 12 July 2021 305:from the original on 7 April 2022 1067:Annals of the Rheumatic Diseases 184: 1252:New Zealand medical researchers 1079:10.1136/annrheumdis-2015-208237 386:"Bone and Joint Research Group" 325:"Dr Nicola Dalbeth Healthpoint" 388:. The University of Auckland. 119:Auckland District Health Board 1: 1000:Arthritis Care & Research 937:Arthritis Care & Research 1147:10.4049/jimmunol.173.10.6418 1267:New Zealand rheumatologists 1237:New Zealand women academics 1201:The Journal of Rheumatology 818:The Journal of Rheumatology 767:The Journal of Rheumatology 1283: 1242:University of Otago alumni 903:The University of Auckland 85:is a New Zealand academic 1262:New Zealand women writers 1134:The Journal of Immunology 710:10.3399/bjgpopen20x101051 661:10.1177/1759720X211028007 73: 48: 1006:(10). Wiley: 1447ā€“1461. 943:(10). Wiley: 1431ā€“1446. 412:"Our Medical Committee" 121:Rheumatology Services. 111:Imperial College London 1073:(10). BMJ: 1789ā€“1798. 558:Maurice Wilkins Centre 487:10.1186/1745-6215-8-38 214:Urate-lowering therapy 163:Dalbeth was elected a 144: 68:University of Auckland 830:10.3899/jrheum.191245 779:10.3899/jrheum.201684 329:www.healthpoint.co.nz 248:inflammatory diseases 139: 266:creatinine clearance 252:rheumatoid arthritis 107:University of Oxford 101:Education and career 655:: 1759720X2110280. 616:. 5 February 2018. 361:. 29 January 2016. 43:University of Otago 216:(ULT) and chronic 194:has a profile for 159:Awards and honours 1012:10.1002/acr.21773 949:10.1002/acr.21772 824:(12): 1815ā€“1821. 200: 125:Selected research 77: 76: 50:Scientific career 1274: 1216: 1215: 1213: 1198: 1189: 1180: 1179: 1149: 1125: 1116: 1115: 1113: 1098: 1064: 1055: 1049: 1048: 1046: 1031: 997: 988: 979: 978: 968: 928: 919: 918: 916: 914: 894: 888: 887: 885: 883: 868: 862: 861: 859: 857: 809: 803: 802: 800: 798: 758: 752: 751: 749: 747: 729: 689: 683: 682: 672: 643:(30 June 2021). 636: 630: 629: 627: 625: 610: 604: 603: 601: 599: 580: 574: 573: 571: 569: 550: 544: 543: 541: 539: 533: 526: 516: 510: 509: 499: 489: 465: 459: 458: 456: 454: 441:Working groups. 438: 432: 431: 429: 427: 408: 402: 401: 399: 397: 381: 375: 374: 372: 370: 351: 345: 344: 342: 340: 321: 315: 314: 312: 310: 299:Gout Study Group 291: 274:renal impairment 198: 188: 187: 84: 21: 1282: 1281: 1277: 1276: 1275: 1273: 1272: 1271: 1222: 1221: 1220: 1219: 1211: 1196: 1191: 1190: 1183: 1127: 1126: 1119: 1111: 1062: 1057: 1056: 1052: 1044: 995: 990: 989: 982: 930: 929: 922: 912: 910: 896: 895: 891: 881: 879: 870: 869: 865: 855: 853: 811: 810: 806: 796: 794: 760: 759: 755: 745: 743: 691: 690: 686: 638: 637: 633: 623: 621: 612: 611: 607: 597: 595: 582: 581: 577: 567: 565: 552: 551: 547: 537: 535: 531: 524: 518: 517: 513: 467: 466: 462: 452: 450: 440: 439: 435: 425: 423: 410: 409: 405: 395: 393: 383: 382: 378: 368: 366: 359:Hutt Valley DHB 353: 352: 348: 338: 336: 323: 322: 318: 308: 306: 293: 292: 288: 283: 218:gouty arthritis 206: 205: 204: 197:Nicola Dalbeth 189: 185: 180: 161: 127: 103: 93:. She supports 82: 39:Alma mater 26: 17: 12: 11: 5: 1280: 1278: 1270: 1269: 1264: 1259: 1254: 1249: 1244: 1239: 1234: 1224: 1223: 1218: 1217: 1181: 1117: 1050: 980: 920: 889: 863: 804: 753: 684: 641:Stamp, Lisa K. 631: 605: 575: 545: 511: 460: 433: 403: 376: 346: 316: 285: 284: 282: 279: 278: 277: 255: 233: 227: 221: 190: 183: 182: 181: 179: 176: 160: 157: 126: 123: 102: 99: 87:rheumatologist 80:Nicola Dalbeth 75: 74: 71: 70: 65: 61: 60: 57: 53: 52: 46: 45: 40: 36: 35: 32: 28: 27: 25:Nicola Dalbeth 24: 15: 13: 10: 9: 6: 4: 3: 2: 1279: 1268: 1265: 1263: 1260: 1258: 1255: 1253: 1250: 1248: 1245: 1243: 1240: 1238: 1235: 1233: 1232:Living people 1230: 1229: 1227: 1210: 1206: 1202: 1195: 1188: 1186: 1182: 1177: 1173: 1169: 1165: 1161: 1157: 1153: 1148: 1143: 1139: 1135: 1131: 1124: 1122: 1118: 1110: 1106: 1102: 1097: 1092: 1088: 1084: 1080: 1076: 1072: 1068: 1061: 1054: 1051: 1043: 1039: 1035: 1030: 1025: 1021: 1017: 1013: 1009: 1005: 1001: 994: 987: 985: 981: 976: 972: 967: 962: 958: 954: 950: 946: 942: 938: 934: 927: 925: 921: 908: 904: 900: 893: 890: 877: 873: 867: 864: 851: 847: 843: 839: 835: 831: 827: 823: 819: 815: 808: 805: 792: 788: 784: 780: 776: 772: 768: 764: 757: 754: 741: 737: 733: 728: 723: 719: 715: 711: 707: 703: 699: 695: 688: 685: 680: 676: 671: 666: 662: 658: 654: 650: 646: 642: 635: 632: 619: 615: 609: 606: 593: 589: 585: 579: 576: 563: 559: 555: 549: 546: 530: 523: 522: 515: 512: 507: 503: 498: 493: 488: 483: 479: 475: 471: 464: 461: 448: 444: 437: 434: 421: 417: 413: 407: 404: 391: 387: 380: 377: 364: 360: 356: 350: 347: 334: 330: 326: 320: 317: 304: 300: 296: 290: 287: 280: 275: 271: 270:hyperuricemia 267: 263: 259: 256: 253: 249: 245: 241: 237: 234: 231: 228: 225: 222: 219: 215: 211: 208: 207: 202: 201: 193: 177: 175: 173: 168: 166: 158: 156: 152: 149: 143: 138: 135: 132: 124: 122: 120: 114: 112: 108: 100: 98: 96: 92: 88: 81: 72: 69: 66: 62: 58: 54: 51: 47: 44: 41: 37: 34:New Zealander 33: 29: 22: 19: 1204: 1200: 1137: 1133: 1070: 1066: 1053: 1003: 999: 940: 936: 911:. 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OMERACT. 262:allopurinol 199:(Q56192234) 31:Nationality 1226:Categories 480:(38): 38. 281:References 1156:0022-1767 1087:0003-4967 1020:2151-464X 957:2151-464X 846:212730804 787:235711900 718:2398-3795 698:BJGP Open 244:monocytes 240:(N cells) 1209:Archived 1176:Archived 1172:26744867 1164:15528382 1109:Archived 1105:26359487 1042:Archived 1038:23024029 975:23024028 907:Archived 876:Archived 850:Archived 838:32173653 791:Archived 740:Archived 736:32636201 679:34262623 618:Archived 592:Archived 562:Archived 529:Archived 527:. 2020. 506:18039364 447:Archived 420:Archived 418:. 2020. 390:Archived 363:Archived 333:Archived 303:Archived 301:. 2018. 250:such as 95:clinical 1096:4602275 1029:3662546 966:3683400 913:13 July 882:8 April 856:8 April 797:13 July 746:8 April 727:7465587 670:8252336 624:8 April 598:8 April 568:8 April 538:8 April 497:2169260 453:8 April 426:8 April 396:8 April 369:8 April 339:8 April 309:8 April 192:Scholia 1170:  1162:  1154:  1103:  1093:  1085:  1036:  1026:  1018:  973:  963:  955:  844:  836:  785:  734:  724:  716:  677:  667:  504:  494:  474:Trials 56:Fields 1212:(PDF) 1197:(PDF) 1168:S2CID 1112:(PDF) 1063:(PDF) 1045:(PDF) 996:(PDF) 842:S2CID 783:S2CID 773:(1). 532:(PDF) 83:FRSNZ 1160:PMID 1152:ISSN 1101:PMID 1083:ISSN 1034:PMID 1016:ISSN 971:PMID 953:ISSN 915:2021 884:2022 858:2022 834:PMID 799:2021 748:2022 732:PMID 714:ISSN 675:PMID 626:2022 600:2022 588:adhb 570:2022 540:2022 502:PMID 455:2022 428:2022 398:2022 371:2022 341:2022 311:2022 131:gout 109:and 91:gout 1142:doi 1138:173 1091:PMC 1075:doi 1024:PMC 1008:doi 961:PMC 945:doi 826:doi 775:doi 722:PMC 706:doi 665:PMC 657:doi 492:PMC 482:doi 1228:: 1207:. 1205:33 1203:. 1199:. 1184:^ 1174:. 1166:. 1158:. 1150:. 1136:. 1132:. 1120:^ 1107:. 1099:. 1089:. 1081:. 1071:74 1069:. 1065:. 1040:. 1032:. 1022:. 1014:. 1004:64 1002:. 998:. 983:^ 969:. 959:. 951:. 941:64 939:. 935:. 923:^ 905:. 901:. 848:. 840:. 832:. 822:47 820:. 816:. 789:. 781:. 771:48 769:. 765:. 738:. 730:. 720:. 712:. 700:. 696:. 673:. 663:. 653:13 651:. 647:. 586:. 560:. 556:. 500:. 490:. 476:. 472:. 414:. 357:. 331:. 327:. 297:. 276:." 254:." 1144:: 1077:: 1010:: 977:. 947:: 917:. 886:. 860:. 828:: 801:. 777:: 750:. 708:: 702:4 681:. 659:: 628:. 602:. 572:. 542:. 508:. 484:: 478:8 457:. 430:. 400:. 373:. 343:. 313:. 203:. 171:"

Index

University of Otago
University of Auckland
rheumatologist
gout
clinical
University of Oxford
Imperial College London
Auckland District Health Board
gout
Fellow of the Royal Society of New Zealand
Scholia
Nicola Dalbeth (Q56192234)
Urate-lowering therapy
gouty arthritis
(N cells)
monocytes
inflammatory diseases
rheumatoid arthritis
allopurinol
creatinine clearance
hyperuricemia
renal impairment
"Professor Nicola Dalbeth, MBChB, MD, FRACP"
Archived
"Dr Nicola Dalbeth Healthpoint"
Archived
"Men, Māori and Pacific people need better gout medication"
Archived
"Bone and Joint Research Group"
Archived

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