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Otto Herbert Wolff

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33: 424:. Wolff was the first trained scientist to work within pediatrics, in a clinical chair in the UK, and used the position to push the scientific based treatment of babies and the very young. During his time at the institute, Wolff turned was as essentially a collection of pre-war cottage hospitals into a world class centre for children. 338:
moved to Italy, Wolff found he was responsible for the caring of Italian prisoners of war. When Wolff found that a prisoner was ill, they would be allowed home to their families, and Wolff found it was hard to maintain a doubtful view when ailments were often fictitious.
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Smith, Isabel; Beasley, Martin G.; Wolff, Otto H.; Ades, Anthony E. (March 1988). "Behavior disturbance in 8-year-old children with early treated phenylketonuria: Report from the MRC/DHSS phenylketonuria register".
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SALT, HB; WOLFF, OH; LLOYD, JK; FOSBROOKE, AS; CAMERON, AH; HUBBLE, DV. (13 August 1960). "On having no beta-lipoprotein. A syndrome comprising a-beta-lipoproteinaemia, acanthocytosis, and steatorrhoea".
256:, who was born in Manchester to a British mother and his mother was Anna Samson, was the daughter of a lawyer. Wolff therefore had dual nationality. Herbert Wolff was a doctor, who served in the 279:
to study Medicine, a position his brother Heinz already held. In 1937, the whole family emigrated to England, but upon arriving, his father realised that his medical degree from the
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Smith, I.; Clayton, B.E.; Wolff, O.H. (17 May 1975). "New Variant of Phenylketonuria with Progressive Neurological Illness Unresponsive to Phenylalanine Restriction".
1756: 378:, a disorder of blood lipids, that interferes with the normal absorption of fat and fat-soluble vitamins from food, and designed new special diets for babies with 1736: 458:, and in 1986 the medal of the Association Française pour le Dépistage et le Prévention des Maladies Métaboliques et des Handicaps de l’Enfant. 1987 brought the 1731: 471: 432: 190: 197: 1751: 374:. During the period while he was attending the university, Wolff received laboratory training and the scientific basis of medicine. He discovered 1452: 408:
In 1965, Wolff moved to London and was appointed the second Nuffield Professor of Child Health at the Institute of Child Health and consultant
962: 271:, and despite his Jewish background, was well received by his classmates. However, when he turned 16, Wolff was sent to London to study at a 1190: 1053: 1092: 213:. Wolff was notable for being one of the first paediatricians in Britain to set up a clinic for obese children. Later research into 1600: 1405: 1197: 346:. When returning from war, Wolff had a chance meeting with a senior doctor, that resulted in Wolff taking a position at the 1721: 1689: 1577: 1511: 1488: 1417: 1340: 765:
Smith, I.; Lobascher, M.E.; Stevenson, J.E.; Wolff, O.H.; Schmidt, H.; rubel-Kaiser, S.; Bickel, H. (9 September 1978).
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becoming a lecturer in the Department of Child Health. Wolf finished his academic career at Birmingham University as a
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EDWARDS, JH; HARNDEN, DG; CAMERON, AH; CROSSE, VM; WOLFF, OH (9 April 1960). "A new trisomic syndrome".
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Muller, D.P.R; Lloyd, June K.; Wolff, O.H (29 January 1983). "Vitamin E and Neurological Function".
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HADORN, B; TARLOW, M. J.; LLOYD, J. K.; WOLFF, O. H. (1969). "Intestinal enterokinase deficiency".
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Wolff was born the younger of two boys. Wolff's British father, Herbert Arnold Jacob Wolff, was a
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Baar, H.S.; Wolff, O.H. (20 April 1957). "Pancreatic Necrosis in Cortisone-Treated Children".
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was not recognised in the UK. So Herbert Arnold Jacob Wolff studied Medicine at
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and qualified in medicine in 1943, and then held a number of junior posts at
1052:. Royal College of Physicians: Royal College of Physicians. 21 August 2013. 534: 308: 264:, and during the interwar period, lived as a comfortable family in Germany. 1172: 862: 837: 782: 721: 640: 614: 509: 287:
while both his sons studied Medicine in Cambridge. Wolff earned a place at
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Lloyd, June K.; Wolff, O. H.; Whelen, W. S. (15 July 1961).
205:, died 27 April 2010) was a German born medical scientist, 462:
from the Action Research for the Crippled Child, later the
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Milla, PJ; Aggett, PJ; Wolff, OH; Harries, JT (1957).
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These are some of Otto Wolff's most important papers.
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and his recognition in 1960 of the rare condition of
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W. Rubinstein; Michael A. Jolles (27 January 2011).
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School of Medical Sciences, University of Manchester
1664: 1587: 1504: 1427: 1350: 1285: 1221: 157: 143: 118: 103: 89: 79: 67: 42: 23: 209:and was the Nuffield Professor of Child Health at 995:The Royal College of Paediatrics and Child Health 401:, i.e. the chromosomal abnormality that leads to 397:Wolff also provided the first description of the 954:The Palgrave Dictionary of Anglo-Jewish History 1727:Commanders of the Order of the British Empire 1198: 472:Royal College of Paediatrics and Child Health 433:Royal College of Paediatrics and Child Health 8: 37:Otto Wolff being awarded James Spence medal. 777:(6139). BMJ Publishing Group Ltd: 723–726. 350:to train in paediatrics. Working under the 1747:Physicians of Great Ormond Street Hospital 1742:Fellows of the Royal College of Physicians 1205: 1191: 1183: 1132:. Times Newspapers. The Times. 5 July 2010 420:. The previous Nuffield Professor was Sir 20: 878: 790: 630: 542: 529:(6283). BMJ Publishing Group Ltd: 13–17. 431:helped to establish the formation of the 1124: 1122: 1120: 1118: 1116: 1114: 1112: 1110: 1036: 1034: 1032: 957:. Palgrave Macmillan UK. p. 1035. 940: 857:(11). BMJ Publishing Group: 1028–1033. 517:Stark, O; Atkins, E; Wolff, OH (1981). 1757:German emigrants to the United Kingdom 1030: 1028: 1026: 1024: 1022: 1020: 1018: 1016: 1014: 1012: 267:Wolff's early schooling took place in 236:. Wolff was also co-discoverer of the 1737:Alumni of the University of Cambridge 1087: 1085: 1083: 1081: 1079: 1077: 1075: 1073: 1071: 1056:from the original on 28 December 2017 985: 983: 981: 362:. In 1951, Wolff started work at the 299:Wolff started his clinical career at 7: 1732:Recipients of the James Spence Medal 466:. Wolff was awarded the prestigious 275:, so that he could earn a place at 14: 1046:Munks Roll – Lives of the Fellows 31: 1093:"Professor Otto Wolff Obituary" 1752:20th-century German physicians 991:"Professor Otto Herbert Wolff" 452:Dawson Williams Memorial Prize 450:In 1985 Wolff was awarded the 303:, that had to be evacuated to 127:Dawson Williams Memorial Prize 1: 1447:Richard Worthington Smithells 1406:Frederick John William Miller 1335:Seymour Donald Mayneord Court 1165:10.1016/s0140-6736(60)90675-9 911:10.1016/S0022-3476(88)80320-2 822:10.1016/S0140-6736(57)90974-1 750:10.1016/s0140-6736(69)92071-6 702:Quarterly Journal of Medicine 662:10.1016/S0140-6736(75)92498-8 574:10.1016/S0140-6736(83)92598-9 502:10.1016/s0140-6736(60)91478-1 318:In 1944, close to the end of 16:German born medical scientist 414:Great Ormond Street Hospital 224:pioneered the techniques of 211:Great Ormond Street Hospital 170:Great Ormond Street Hospital 456:British Medical Association 301:University College Hospital 226:lipoprotein electrophoresis 108:lipoprotein electrophoresis 1773: 1329:Ronald Stanley Illingworth 1258:Robert Royston Amos Coombs 386:that results in decreased 384:inborn error of metabolism 899:The Journal of Pediatrics 330:, and was in charge of a 201:(born 10 January 1920 in 179: 136: 30: 364:University of Birmingham 348:University of Birmingham 326:, attaining the rank of 324:Royal Army Medical Corps 281:University of Strasbourg 166:University of Birmingham 1560:Jonathan Richard Sibert 1394:John Peter Mills Tizard 1305:Ronald Charles MacKeith 1246:Lionel Sharples Penrose 1240:Frank Macfarlane Burnet 603:British Medical Journal 535:10.1136/bmj.283.6283.13 464:Action Medical Research 342:During 1947, Wolff was 230:coronary artery disease 1418:David Cornelius Morley 1382:James W. Bruce Douglas 1358:James Mourilyan Tanner 863:10.1136/gut.20.11.1028 783:10.1136/bmj.2.6139.723 615:10.1136/bmj.2.5245.145 1459:Osmund Royle Reynolds 1341:Kenneth William Cross 1293:Douglas Vernon Hubble 1229:Alan Moncrieff (1960) 693:WOLFF, O. H. (1955). 234:abetalipoproteinaemia 112:abetalipoproteinaemia 94:Peterhouse, Cambridge 1722:German pediatricians 1619:Albert Aynsley-Green 1042:"Otto Herbert Wolff" 447:in 1985 with a CBE. 418:University of London 376:Abetalipoproteinemia 370:under Professor Sir 322:, Wolff joined the 277:Cambridge University 174:University of London 98:Cambridge University 1465:Richard H. R. White 1376:John Oldroyd Forfar 1311:Cyril Astley Clarke 1270:Donald W. Winnicott 656:(7916): 1108–1111. 599:"Childhood Obesity" 334:hospital. When the 313:St Olave's Hospital 162:St Olave's Hospital 1637:Terence Stephenson 1483:Forrester Cockburn 1412:Otto Herbert Wolff 1388:Neil Simson Gordon 1317:Edward John Bowlby 1215:James Spence Medal 1213:Recipients of the 468:James Spence Medal 439:Awards and honours 427:Wolf's work after 186:Otto Herbert Wolff 152:Biomedical science 131:James Spence Medal 25:Otto Herbert Wolff 1699: 1698: 1530:Catherine Peckham 1435:Leonard B. Strang 1276:Geoffrey S. Dawes 964:978-0-230-30466-6 816:(6973): 812–815. 744:(7599): 812–813. 609:(5245): 145–148. 568:(8318): 225–228. 358:, Wolff become a 183: 182: 138:Scientific career 110:, recognition of 1764: 1607:Anthony Costello 1601:Andrew Wilkinson 1441:John Allen Davis 1400:John Lewis Emery 1370:Dermod MacCarthy 1323:Douglas Gairdner 1207: 1200: 1193: 1184: 1177: 1176: 1159:(7128): 787–90. 1148: 1142: 1141: 1139: 1137: 1126: 1105: 1104: 1102: 1100: 1089: 1066: 1065: 1063: 1061: 1038: 1007: 1006: 1004: 1002: 987: 976: 975: 973: 971: 948: 930: 892: 882: 841: 804: 794: 761: 732: 730: 728: 699: 689: 644: 634: 593: 556: 546: 513: 470:in 1988, by the 403:Edwards syndrome 399:genetic disorder 238:Edwards syndrome 200: 195: 74: 52: 50: 35: 21: 1772: 1771: 1767: 1766: 1765: 1763: 1762: 1761: 1702: 1701: 1700: 1695: 1660: 1613:Sheila Shribman 1583: 1566:Victor Dubowitz 1500: 1423: 1364:Elsie Widdowson 1346: 1281: 1252:Cicely Williams 1217: 1211: 1181: 1180: 1150: 1149: 1145: 1135: 1133: 1128: 1127: 1108: 1098: 1096: 1091: 1090: 1069: 1059: 1057: 1040: 1039: 1010: 1000: 998: 989: 988: 979: 969: 967: 965: 950: 949: 942: 937: 895: 844: 807: 764: 735: 726: 724: 708:(94): 109–123. 697: 692: 647: 596: 559: 516: 496:(7146): 325–9. 486: 480: 441: 380:phenylketonuria 356:Leonard Parsons 297: 250: 193: 189: 72: 63: 54: 53:10 January 1920 48: 46: 38: 26: 17: 12: 11: 5: 1770: 1768: 1760: 1759: 1754: 1749: 1744: 1739: 1734: 1729: 1724: 1719: 1714: 1704: 1703: 1697: 1696: 1694: 1693: 1690:Andrew Pollard 1687: 1681: 1678:Henry Halliday 1675: 1668: 1666: 1662: 1661: 1659: 1658: 1652: 1646: 1643:Anne Greenough 1640: 1634: 1628: 1622: 1616: 1610: 1604: 1598: 1595:Malcolm Levene 1591: 1589: 1585: 1584: 1582: 1581: 1575: 1569: 1563: 1557: 1551: 1548:Cyril Chantler 1545: 1539: 1533: 1527: 1524:Martin Barratt 1521: 1515: 1508: 1506: 1502: 1501: 1499: 1498: 1492: 1486: 1480: 1477:Barbara Ansell 1474: 1468: 1462: 1456: 1450: 1444: 1438: 1431: 1429: 1425: 1424: 1422: 1421: 1415: 1409: 1403: 1397: 1391: 1385: 1379: 1373: 1367: 1361: 1354: 1352: 1348: 1347: 1345: 1344: 1338: 1332: 1326: 1320: 1314: 1308: 1302: 1296: 1289: 1287: 1283: 1282: 1280: 1279: 1273: 1267: 1261: 1255: 1249: 1243: 1237: 1234:Robert McCance 1231: 1225: 1223: 1219: 1218: 1212: 1210: 1209: 1202: 1195: 1187: 1179: 1178: 1143: 1106: 1067: 1008: 977: 963: 939: 938: 936: 933: 932: 931: 905:(3): 403–408. 893: 842: 805: 762: 733: 690: 645: 594: 557: 514: 479: 476: 440: 437: 422:Alan Moncrieff 372:Douglas Hubble 296: 293: 249: 246: 181: 180: 177: 176: 159: 155: 154: 145: 141: 140: 134: 133: 120: 116: 115: 105: 104:Known for 101: 100: 91: 87: 86: 81: 77: 76: 75:(aged 90) 69: 65: 64: 55: 44: 40: 39: 36: 28: 27: 24: 15: 13: 10: 9: 6: 4: 3: 2: 1769: 1758: 1755: 1753: 1750: 1748: 1745: 1743: 1740: 1738: 1735: 1733: 1730: 1728: 1725: 1723: 1720: 1718: 1715: 1713: 1710: 1709: 1707: 1691: 1688: 1685: 1684:Imti Choonara 1682: 1679: 1676: 1673: 1672:Catherine Law 1670: 1669: 1667: 1663: 1656: 1653: 1650: 1649:Frances Cowan 1647: 1644: 1641: 1638: 1635: 1632: 1629: 1626: 1623: 1620: 1617: 1614: 1611: 1608: 1605: 1602: 1599: 1596: 1593: 1592: 1590: 1586: 1579: 1578:Neil McIntosh 1576: 1573: 1570: 1567: 1564: 1561: 1558: 1555: 1552: 1549: 1546: 1543: 1540: 1537: 1534: 1531: 1528: 1525: 1522: 1519: 1518:Peter M. Dunn 1516: 1513: 1510: 1509: 1507: 1503: 1496: 1493: 1490: 1487: 1484: 1481: 1478: 1475: 1472: 1469: 1466: 1463: 1460: 1457: 1454: 1451: 1448: 1445: 1442: 1439: 1436: 1433: 1432: 1430: 1426: 1419: 1416: 1413: 1410: 1407: 1404: 1401: 1398: 1395: 1392: 1389: 1386: 1383: 1380: 1377: 1374: 1371: 1368: 1365: 1362: 1359: 1356: 1355: 1353: 1349: 1342: 1339: 1336: 1333: 1330: 1327: 1324: 1321: 1318: 1315: 1312: 1309: 1306: 1303: 1300: 1299:Wilfrid Payne 1297: 1294: 1291: 1290: 1288: 1284: 1277: 1274: 1271: 1268: 1265: 1264:Mary Sheridan 1262: 1259: 1256: 1253: 1250: 1247: 1244: 1241: 1238: 1235: 1232: 1230: 1227: 1226: 1224: 1220: 1216: 1208: 1203: 1201: 1196: 1194: 1189: 1188: 1185: 1174: 1170: 1166: 1162: 1158: 1154: 1147: 1144: 1131: 1125: 1123: 1121: 1119: 1117: 1115: 1113: 1111: 1107: 1094: 1088: 1086: 1084: 1082: 1080: 1078: 1076: 1074: 1072: 1068: 1055: 1051: 1047: 1043: 1037: 1035: 1033: 1031: 1029: 1027: 1025: 1023: 1021: 1019: 1017: 1015: 1013: 1009: 996: 992: 986: 984: 982: 978: 966: 960: 956: 955: 947: 945: 941: 934: 928: 924: 920: 916: 912: 908: 904: 900: 894: 890: 886: 881: 876: 872: 868: 864: 860: 856: 852: 848: 843: 839: 835: 831: 827: 823: 819: 815: 811: 806: 802: 798: 793: 788: 784: 780: 776: 772: 768: 763: 759: 755: 751: 747: 743: 739: 734: 723: 719: 715: 711: 707: 703: 696: 691: 687: 683: 679: 675: 671: 667: 663: 659: 655: 651: 646: 642: 638: 633: 628: 624: 620: 616: 612: 608: 604: 600: 595: 591: 587: 583: 579: 575: 571: 567: 563: 558: 554: 550: 545: 540: 536: 532: 528: 524: 520: 515: 511: 507: 503: 499: 495: 491: 485: 484: 483: 477: 475: 473: 469: 465: 461: 460:Harding Award 457: 453: 448: 446: 438: 436: 434: 430: 425: 423: 419: 415: 411: 410:paediatrician 406: 404: 400: 396: 395:phenylalanine 393: 389: 385: 381: 377: 373: 369: 365: 361: 357: 353: 349: 345: 340: 337: 333: 329: 325: 321: 316: 314: 310: 306: 302: 294: 292: 290: 286: 282: 278: 274: 270: 265: 263: 259: 255: 247: 245: 243: 239: 235: 231: 227: 223: 219: 216: 212: 208: 207:paediatrician 204: 199: 192: 187: 178: 175: 171: 167: 163: 160: 156: 153: 149: 146: 142: 139: 135: 132: 128: 124: 121: 117: 113: 109: 106: 102: 99: 95: 92: 88: 85: 82: 78: 71:27 April 2010 70: 66: 62: 58: 45: 41: 34: 29: 22: 19: 1631:David Dunger 1625:Ieuan Hughes 1512:Hugh Jackson 1489:David Harvey 1411: 1156: 1152: 1146: 1134:. Retrieved 1130:"Otto Wolff" 1097:. Retrieved 1058:. Retrieved 1049: 1045: 999:. Retrieved 994: 968:. Retrieved 953: 902: 898: 854: 850: 813: 809: 774: 770: 741: 737: 725:. Retrieved 705: 701: 653: 649: 606: 602: 565: 561: 526: 522: 493: 489: 481: 478:Bibliography 449: 442: 429:World War II 426: 407: 341: 320:World War II 317: 298: 266: 251: 240:in abnormal 185: 184: 158:Institutions 137: 73:(2010-04-27) 18: 1717:2010 deaths 1712:1920 births 1542:Lewis Spitz 344:demobilised 315:in London. 307:due to the 273:Cram school 262:World War I 258:German Army 242:chromosomes 222:Harold Salt 80:Nationality 1706:Categories 1655:Alan Emond 1572:Alan Craft 1554:Alan Lucas 1536:David Hall 1495:Roy Meadow 1471:David Hull 1453:June Lloyd 935:References 810:The Lancet 738:The Lancet 650:The Lancet 562:The Lancet 443:Wolff was 392:amino acid 388:metabolism 352:consultant 289:Peterhouse 148:Pediatrics 49:1920-01-10 919:0022-3476 871:0017-5749 830:0140-6736 714:0033-5622 670:0140-6736 623:0007-1447 454:from the 360:registrar 291:college. 90:Education 1173:13819419 1054:Archived 838:13417603 771:Br Med J 722:14395422 686:19404792 641:13762916 590:30492091 510:13745738 445:Knighted 416:and the 332:smallpox 927:3346777 880:1412682 792:1607584 758:4180366 727:28 June 632:1969164 582:6130255 553:6788242 544:1506053 390:of the 336:theatre 328:Captain 305:Cardiff 269:Hamburg 260:during 203:Hamburg 61:Germany 57:Hamburg 1692:(2023) 1686:(2022) 1680:(2021) 1674:(2020) 1657:(2019) 1651:(2018) 1645:(2017) 1639:(2016) 1633:(2015) 1627:(2014) 1621:(2013) 1615:(2012) 1609:(2011) 1603:(2011) 1597:(2010) 1580:(2009) 1574:(2008) 1568:(2007) 1562:(2006) 1556:(2006) 1550:(2005) 1544:(2004) 1538:(2004) 1532:(2003) 1526:(2002) 1520:(2001) 1514:(2000) 1497:(1999) 1491:(1999) 1485:(1998) 1479:(1997) 1473:(1996) 1467:(1995) 1461:(1994) 1455:(1993) 1449:(1992) 1443:(1991) 1437:(1990) 1420:(1989) 1414:(1988) 1408:(1987) 1402:(1987) 1396:(1986) 1390:(1985) 1384:(1984) 1378:(1983) 1372:(1982) 1366:(1981) 1360:(1980) 1343:(1979) 1337:(1978) 1331:(1977) 1325:(1976) 1319:(1974) 1313:(1973) 1307:(1972) 1301:(1971) 1295:(1970) 1278:(1969) 1272:(1968) 1266:(1968) 1260:(1967) 1254:(1965) 1248:(1964) 1242:(1963) 1236:(1961) 1171:  1153:Lancet 1136:31 May 1099:24 May 1060:24 May 1001:24 May 970:24 May 961:  925:  917:  889:527871 887:  877:  869:  836:  828:  801:698696 799:  789:  756:  720:  712:  684:  676:  668:  639:  629:  621:  588:  580:  551:  541:  508:  490:Lancet 368:Reader 295:Career 218:lipids 215:plasma 144:Fields 119:Awards 84:German 1665:2020s 1588:2010s 1505:2000s 1428:1990s 1351:1980s 1286:1970s 1222:1960s 698:(pdf) 682:S2CID 678:49470 586:S2CID 382:, an 309:Blitz 220:with 196: 194:, 1169:PMID 1138:2018 1101:2018 1062:2018 1003:2018 972:2018 959:ISBN 923:PMID 915:ISSN 885:PMID 867:ISSN 834:PMID 826:ISSN 797:PMID 754:PMID 729:2018 718:PMID 710:ISSN 674:PMID 666:ISSN 637:PMID 619:ISSN 578:PMID 549:PMID 506:PMID 354:Sir 248:Life 198:FRCP 68:Died 43:Born 1161:doi 1050:XII 907:doi 903:112 875:PMC 859:doi 851:GUT 818:doi 814:269 787:PMC 779:doi 746:doi 658:doi 654:305 627:PMC 611:doi 570:doi 566:321 539:PMC 531:doi 527:283 523:BMJ 498:doi 412:at 191:CBE 123:CBE 1708:: 1167:. 1155:. 1109:^ 1070:^ 1048:. 1044:. 1011:^ 993:. 980:^ 943:^ 921:. 913:. 901:. 883:. 873:. 865:. 855:20 853:. 849:. 832:. 824:. 812:. 795:. 785:. 773:. 769:. 752:. 740:. 716:. 706:24 704:. 700:. 680:. 672:. 664:. 652:. 635:. 625:. 617:. 605:. 601:. 584:. 576:. 564:. 547:. 537:. 525:. 521:. 504:. 492:. 474:. 435:. 254:GP 244:. 188:, 172:, 168:, 164:, 150:, 129:, 125:, 96:, 59:, 1206:e 1199:t 1192:v 1175:. 1163:: 1157:1 1140:. 1103:. 1064:. 1005:. 974:. 929:. 909:: 891:. 861:: 840:. 820:: 803:. 781:: 775:2 760:. 748:: 742:1 731:. 688:. 660:: 643:. 613:: 607:2 592:. 572:: 555:. 533:: 512:. 500:: 494:2 114:. 51:) 47:(

Index


Hamburg
Germany
German
Peterhouse, Cambridge
Cambridge University
lipoprotein electrophoresis
abetalipoproteinaemia
CBE
Dawson Williams Memorial Prize
James Spence Medal
Pediatrics
Biomedical science
St Olave's Hospital
University of Birmingham
Great Ormond Street Hospital
University of London
CBE
FRCP
Hamburg
paediatrician
Great Ormond Street Hospital
plasma
lipids
Harold Salt
lipoprotein electrophoresis
coronary artery disease
abetalipoproteinaemia
Edwards syndrome
chromosomes

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