Knowledge (XXG)

Orteronel

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Yamaoka, M; Hara, T; Hitaka, T; Kaku, T; Takeuchi, T; Takahashi, J; Asahi, S; Miki, H; et al. (2012). "Orteronel (TAK-700), a novel non-steroidal 17,20-lyase inhibitor: Effects on steroid synthesis in human and monkey adrenal cells and serum steroid levels in cynomolgus monkeys".
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which is expressed in testicular, adrenal, and prostatic tumor tissues. CYP17 catalyzes two sequential reactions: (a) the conversion of pregnenolone and progesterone to their 17α-hydroxy derivatives by its 17α-hydroxylase activity, and (b) the subsequent formation of
508:
Attard G, Belldegrun AS, de Bono JS (December 2005). "Selective blockade of androgenic steroid synthesis by novel lyase inhibitors as a therapeutic strategy for treating metastatic prostate cancer".
3956: 450: 416:, respectively, by its 17,20-lyase activity. DHEA and androstenedione are androgens and precursors of testosterone. Inhibition of CYP17 activity thus decreases circulating levels of 1653: 569: 2085: 263: 1646: 1615: 3900: 562: 3905: 2385: 3895: 2847: 1639: 1605: 1572: 3890: 1886: 1610: 555: 3951: 2642: 2637: 2235: 1620: 830: 102: 2075: 387: 2304: 241: 3087: 3486: 2391: 2354: 2149: 2080: 895: 875: 595: 2309: 850: 250:
InChI=1S/C18H17N3O2/c1-19-17(22)14-3-2-13-9-15(5-4-12(13)8-14)18(23)6-7-21-11-20-10-16(18)21/h2-5,8-11,23H,6-7H2,1H3,(H,19,22)
1839: 1086: 436: 3077: 1746: 1726: 1348: 1160: 368: 341: 3885: 3855: 3420: 2714: 2575: 2102: 1928: 1741: 1517: 1109: 218: 3936: 2792: 2154: 1756: 1589: 1525: 1050: 804: 629: 2777: 2772: 2580: 3941: 3082: 2314: 1933: 1475: 709: 372: 3424: 2144: 1965: 1923: 1871: 1817: 1301: 1290: 684: 659: 451:"Takeda Announces Termination of Orteronel (TAK-700) Development for Prostate Cancer in Japan, U.S.A. and Europe" 376: 1711: 3926: 3587: 2734: 2703: 2423: 2364: 2097: 1875: 1751: 1701: 880: 705: 3072: 2807: 2787: 1955: 3603: 2530: 2274: 2184: 2092: 1992: 1980: 1881: 1577: 1467: 796: 751: 741: 701: 689: 3595: 3067: 2730: 2369: 2279: 2240: 2112: 1960: 1829: 1778: 885: 791: 697: 693: 634: 409: 142: 3946: 3931: 3127: 2615: 2465: 2359: 2024: 1706: 1509: 1170: 36: 3401: 3287: 2755: 2726: 2699: 2565: 2453: 2262: 2230: 2196: 1918: 1834: 1805: 1521: 1329: 1220: 815: 800: 776: 669: 654: 390:
but failed to extend overall survival rates, and development was voluntarily terminated as a result.
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Trenbolone hexahydrobenzylcarbonate (trenbolone cyclohexylmethylcarbonate)
3827: 3706: 3701: 3696: 3691: 3686: 3492: 3247: 3182: 2998: 2953: 2948: 2943: 2938: 2933: 2888: 2827: 2822: 2762: 1943: 1785: 1549: 1451: 1040: 717: 590: 578: 394: 3783: 3572: 3512: 3312: 3197: 3038: 3013: 2868: 2610: 2560: 2500: 2161: 1000: 618: 404: 194: 23: 3834: 3775: 3760: 3666: 437:
Millennium and Takeda Announce Advancement of Prostate Cancer Program
133: 334:
Except where otherwise noted, data are given for materials in their
182: 3366: 3048: 2958: 113: 101: 91: 3799: 3112: 173: 1635: 551: 3482: 2889:
Andarine (acetamidoxolutamide, androxolutamide, GTx-007, S-4)
2848: 1732:
Adrenosterone (11-ketoandrostenedione, 11-oxoandrostenedione)
467:
The Journal of Steroid Biochemistry and Molecular Biology
2573:
17α-Alkylated 5α-dihydro-19-nortestosterone derivatives:
367:
that was being developed for the treatment of cancer by
2076:
7α-Methyl-19-norandrostenedione (MENT dione, trestione)
2770:
5α-Dihydro-17α-ethynyl-19-nortestosterone derivatives:
3856: 1110: 737:
Androstanolone (stanolone, dihydrotestosterone, DHT)
3768: 3759: 3057: 2846: 2204:
Normethandrone (methylestrenolone, normethisterone)
1686: 1672: 1539: 1401: 1338: 1300: 1289: 1137: 1128: 1059: 976:
Normethandrone (methylestrenolone, normethisterone)
752:
Drostanolone propionate (dromostanolone propionate)
609: 596: 589: 2416:17α-Alkylated 5α-dihydrotestosterone derivatives: 3957:Drugs developed by Takeda Pharmaceutical Company 866:Metandienone (methandienone, methandrostenolone) 206: 2635:5α-Dihydro-17α-ethynyltestosterone derivatives: 77: 2086:11β-Methyl-19-nortestosterone dodecylcarbonate 918:17α-Alkylated dihydrotestosterone derivatives: 2853:Tooltip Selective androgen receptor modulator 2498:17α-Alkylated 19-nortestosterone derivatives: 1647: 958:17α-Alkylated 19-nortestosterone derivatives: 563: 8: 2904:Enobosarm (ostarine, MK-2866, GTx-024, S-22) 777:Metenolone enanthate (methenolone enanthate) 2655:17α-Ethynyl-19-nortestosterone derivatives: 1101: 3765: 2377:Methylclostebol (chloromethyltestosterone) 2272:5α-Dihydro-19-nortestosterone derivatives: 1683: 1654: 1640: 1632: 1297: 1134: 606: 570: 556: 548: 161: 15: 2598:17α-Vinyl-19-nortestosterone derivatives: 2214:Oxabolone cipionate (oxabolone cypionate) 1830:DHEA (androstenolone, prasterone; 5-DHEA) 1674: 1139: 821:Oxabolone cipionate (oxabolone cypionate) 665:Prasterone (dehydroepiandrosterone, DHEA) 611: 226: 2305:Chlorodehydromethylandrostenediol (CDMA) 772:Metenolone acetate (methenolone acetate) 3906:List of androgens and anabolic steroids 2292:17α-Alkylated testosterone derivatives: 838:17α-Alkylated testosterone derivatives: 429: 268: 246: 2310:Chlorodehydromethyltestosterone (CDMT) 2066:Testifenon (testiphenon, testiphenone) 851:Chlorodehydromethyltestosterone (CDMT) 271:O=C(NC)c2ccc1cc(ccc1c2)C4(O)c3cncn3CC4 2591:Norvinisterone (vinylnortestosterone) 2125:Bolmantalate (nandrolone adamantoate) 2120:Bolandione (19-nor-4-androstenedione) 1835:DHEA enanthate (prasterone enanthate) 991:Norvinisterone (vinylnortestosterone) 670:Prasterone enanthate (DHEA enanthate) 403:. It selectively inhibits the enzyme 141: 121: 7: 3861:Tooltip Sex hormone-binding globulin 2608:17α-Ethynyltestosterone derivatives: 1887:Polytestosterone phloretin phosphate 1115:Tooltip human chorionic gonadotropin 998:17α-Ethynyltestosterone derivatives: 2531:Methylhydroxynandrolone (MOHN, MHN) 2236:Trenbolone hexahydrobenzylcarbonate 1896:5α-Dihydrotestosterone derivatives: 1764:Androstenedione (4-androstenedione) 1621:List of androgens/anabolic steroids 601:Tooltip anabolic–androgenic steroid 197: 181: 2588:17α-Vinyltestosterone derivatives: 2350:Methandriol (methylandrostenediol) 1550:Androvax (androstenedione albumin) 988:17α-Vinyltestosterone derivatives: 871:Methandriol (methylandrostenediol) 388:hormone-refractory prostate cancer 14: 2628:Ethisterone (ethynyltestosterone) 2345:Metandienone (methandrostenolone) 2175:Methoxydienone (methoxygonadiene) 1786:Boldione (1,4-androstadienedione) 1737:Androstenediol (5-androstenediol) 1702:4-Dehydroepiandrosterone (4-DHEA) 1616:Progestogens and antiprogestogens 1015:ethisterone (ethynyltestosterone) 675:Prasterone sulfate (DHEA sulfate) 3901:Progesterone receptor modulators 2392:Methyltestosterone 3-hexyl ether 2355:Methandriol bisenanthoyl acetate 2315:Chloromethylandrostenediol (CMA) 2150:Dimethandrolone dodecylcarbonate 1909:1-Androsterone (1-andro, 1-DHEA) 896:Methyltestosterone 3-hexyl ether 876:Methandriol bisenanthoyl acetate 734:Dihydrotestosterone derivatives: 522:10.1111/j.1464-410X.2005.05821.x 304: 298: 48:-methylnaphthalene-2-carboxamide 22: 2073:19-Nortestosterone derivatives: 789:19-Nortestosterone derivatives: 338:(at 25 °C , 100 kPa). 3088:15β-Hydroxycyproterone acetate 2979:OPK-88004 (LY-2452473, TT-701) 1555:Ovandrotone albumin (Fecundin) 1027:norethisterone (norethindrone) 310: 292: 1: 3886:Receptor/signaling modulators 2643:17α-Ethynyl-3β-androstanediol 2638:17α-Ethynyl-3α-androstanediol 2081:11β-Methyl-19-nortestosterone 369:Takeda Pharmaceutical Company 3896:Estrogen receptor modulators 3343:Trimethyltrienolone (R-2956) 2715:Lynestrenol phenylpropionate 2103:19-Nordehydroepiandrosterone 1606:Androgen receptor modulators 1518:hydroxyprogesterone caproate 981:Propetandrol (propethandrol) 911:Tiomesterone (thiomesterone) 439:, Millennium Pharmaceuticals 3891:Androgens and antiandrogens 3662:Ralaniten acetate (EPI-506) 3078:7α-Thiomethylspironolactone 2793:Medroxyprogesterone acetate 2155:Dimethandrolone undecanoate 1966:Dihydromethylandrostenediol 1757:Androstenediol dipropionate 1611:Estrogens and antiestrogens 1547:Androstenedione immunogens: 1526:medroxyprogesterone acetate 1106:Tooltip luteinizing hormone 1051:Medroxyprogesterone acetate 805:nandrolone phenylpropionate 710:testosterone ester mixtures 630:Androstenediol dipropionate 479:10.1016/j.jsbmb.2012.01.001 3973: 3952:Nonsteroidal antiandrogens 1981:Dihydrotestosterone esters 1934:11-Ketodihydrotestosterone 1747:Androstenediol 17β-acetate 1727:11β-Hydroxyandrostenedione 1712:4,17α-Dimethyltestosterone 1476:ethinylestradiol sulfonate 373:Millennium Pharmaceuticals 40:6-(7-Hydroxy-6,7-dihydro-5 3878: 2785:Progesterone derivatives: 2576:5α-Dihydronorethandrolone 2145:Dimethandrolone buciclate 1975:androstanolone, stanolone 1971:Dihydrotestosterone (DHT) 1929:7β-Hydroxyepiandrosterone 1818:Cloxotestosterone acetate 1742:Androstenediol 3β-acetate 1694:Testosterone derivatives: 1679:Tooltip Androgen receptor 1567: 1144:Tooltip Androgen receptor 1048:Progesterone derivatives: 660:Cloxotestosterone acetate 627:Testosterone derivatives: 616:Tooltip Androgen receptor 332: 279: 259: 237: 61: 53: 35: 30: 21: 3591:-Butylbenzenesulfonamide 2778:5α-Dihydronorethisterone 2773:5α-Dihydrolevonorgestrel 2735:norethisterone enanthate 2704:levonorgestrel butanoate 2581:5α-Dihydronormethandrone 2434:Mebolazine (dimethazine) 2424:Desoxymethyltestosterone 2365:Methandriol dipropionate 2162:LS-1727 (nandrolone 17β- 2098:19-Nor-5-androstenedione 1956:Dihydroethyltestosterone 1752:Androstenediol diacetate 931:Mebolazine (dimethazine) 881:Methandriol dipropionate 706:testosterone undecanoate 3722:Topilutamide (fluridil) 3083:11α-Hydroxyprogesterone 2093:19-Nor-5-androstenediol 1993:Drostanolone propionate 1281:Topilutamide (fluridil) 702:testosterone propionate 44:-pyrroloimidazol-7-yl)- 3607:-Desmethylenzalutamide 3313:SC-5233 (spirolactone) 2731:norethisterone acetate 2370:Methandriol propionate 2241:Trenbolone undecanoate 2113:Bolandiol dipropionate 1961:Dihydrofluoxymesterone 1924:5α-Androst-2-en-17-one 1779:Boldenone undecylenate 886:Methandriol propionate 792:Bolandiol dipropionate 698:testosterone enanthate 694:testosterone cypionate 635:Boldenone undecylenate 410:dehydroepiandrosterone 3599:-Desmethylapalutamide 3128:Chlormadinone acetate 3073:7α-Thiospironolactone 2944:LGD-2941 (LGD-122941) 2934:LG121071 (LGD-121071) 2808:3-Keto-5α-abiraterone 2788:6α-Methylprogesterone 2727:Norethisterone esters 2700:Levonorgestrel esters 2616:Ethinylandrostenediol 2466:Methyl-1-testosterone 2386:+esterified estrogens 2360:Methandriol diacetate 2025:Mesterolone cipionate 1707:4-Hydroxytestosterone 1510:chlormadinone acetate 1171:Chlormadinone acetate 742:Androstanolone esters 3288:Potassium canrenoate 2756:Quingestanol acetate 2566:Tetrahydrogestrinone 2454:Metenolone enanthate 2280:5α-Dihydrotrestolone 2275:5α-Dihydronandrolone 2263:Trestolone enanthate 2231:Trenbolone enanthate 2197:Norclostebol acetate 1806:Clostebol propionate 1522:gestonorone caproate 1330:Saw palmetto extract 1221:Potassium canrenoate 816:Norclostebol acetate 801:nandrolone decanoate 655:Clostebol propionate 449:MarketWatch (2014). 371:in conjunction with 3811:Dihydrotestosterone 3806:Dehydroandrosterone 3657:Ralaniten (EPI-002) 3538:Inocoterone acetate 3263:Nomegestrol acetate 3163:Delmadinone acetate 3153:Cyproterone acetate 3098:Abiraterone acetate 3068:7α-Thioprogesterone 2678:Etynodiol diacetate 1882:Testosterone esters 1825:Dehydroandrosterone 1722:11-Ketotestosterone 1514:cyproterone acetate 1422:prolactin releasers 1364:Cyproterone acetate 1346:Abiraterone acetate 1206:Nomegestrol acetate 1181:Delmadinone acetate 1176:Cyproterone acetate 1158:Abiraterone acetate 690:Testosterone esters 375:. It completed two 328: g·mol 18: 3937:CYP17A1 inhibitors 2648:Dihydroethisterone 2511:Dimethyltrienolone 2471:Methylepitiostanol 2449:Metenolone acetate 2382:Methyltestosterone 2285:19-Norandrosterone 2258:Trestolone acetate 2226:Trenbolone acetate 2170:-nitrosocarbamate) 2059:Stenbolone acetate 1949:Bolazine capronate 1801:Clostebol caproate 1594:Never to phase III 1460:diethylstilbestrol 1087:GnRH (gonadorelin) 891:Methyltestosterone 826:Trenbolone acetate 782:Stenbolone acetate 747:Bolazine capronate 650:Clostebol caproate 342:Infobox references 16: 3942:Enzyme inhibitors 3914: 3913: 3874: 3873: 3844: 3837: 3830: 3823: 3755: 3754: 3278:Osaterone acetate 3238:Megestrol acetate 3103:Allyltestosterone 2879:Acetothiolutamide 2798:Megestrol acetate 2601:Vinyltestosterone 2506:Dimethyldienolone 2325:Ethyltestosterone 2253:Trestolone (MENT) 2185:Nandrolone esters 2166:-(2-chloroethyl)- 2042:Nisterime acetate 1919:3α-Androstanediol 1904:1-Androstenedione 1813:Cloxotestosterone 1796:Clostebol acetate 1717:5-Androstenedione 1663:Androgen receptor 1629: 1628: 1563: 1562: 1530:megestrol acetate 1403:Antigonadotropins 1397: 1396: 1354:Aminoglutethimide 1211:Osaterone acetate 1201:Megestrol acetate 1124: 1123: 797:Nandrolone esters 645:Clostebol acetate 365:CYP17A1 inhibitor 350:Chemical compound 348: 347: 103:Interactive image 3964: 3862: 3858: 3842: 3835: 3828: 3821: 3766: 3548:Ketodarolutamide 3528:Hydroxyflutamide 3485:(via metabolite 2854: 2850: 2805:Others/unsorted: 2476:Methylstenbolone 2340:Hydroxystenozole 1899:1-Androstenediol 1697:4-Androstenediol 1684: 1680: 1676: 1656: 1649: 1642: 1633: 1496:GnRH antagonists 1472:ethinylestradiol 1468:estradiol esters 1298: 1145: 1141: 1135: 1116: 1112: 1107: 1103: 1061:Progonadotropins 726:Testoviron Depot 617: 613: 607: 602: 598: 572: 565: 558: 549: 542: 541: 505: 499: 498: 461: 455: 454: 446: 440: 434: 393:Orteronel is an 327: 312: 306: 300: 294: 287:Chemical formula 230: 210: 199: 185: 165: 145: 125: 105: 81: 26: 19: 3972: 3971: 3967: 3966: 3965: 3963: 3962: 3961: 3927:Abandoned drugs 3917: 3916: 3915: 3910: 3870: 3860: 3751: 3473:Cyanonilutamide 3402:Bavdegalutamide 3213:Epitestosterone 3053: 2884:Acetoxolutamide 2852: 2842: 2551:Norethandrolone 2526:Methyldienolone 2330:Fluoxymesterone 2140:Dimethandrolone 2000:Epiandrosterone 1678: 1668: 1660: 1630: 1625: 1599: 1584:Clinical trials 1559: 1535: 1414: 1393: 1334: 1292: 1291:Steroidogenesis 1285: 1143: 1120: 1114: 1105: 1055: 971:Norethandrolone 856:Fluoxymesterone 615: 600: 593: 585: 576: 546: 545: 507: 506: 502: 473:(3–5): 115–28. 463: 462: 458: 448: 447: 443: 435: 431: 426: 414:androstenedione 380:clinical trials 351: 344: 339: 325: 315: 309: 303: 297: 289: 275: 272: 267: 266: 255: 252: 251: 245: 244: 233: 213: 200: 188: 168: 148: 128: 108: 95: 84: 71: 57: 49: 12: 11: 5: 3970: 3968: 3960: 3959: 3954: 3949: 3944: 3939: 3934: 3929: 3919: 3918: 3912: 3911: 3909: 3908: 3903: 3898: 3893: 3888: 3883: 3879: 3876: 3875: 3872: 3871: 3869: 3868: 3863: 3853: 3848: 3824:-α-Amino acids 3818: 3813: 3808: 3803: 3772: 3770: 3763: 3757: 3756: 3753: 3752: 3750: 3749: 3744: 3739: 3734: 3729: 3724: 3719: 3714: 3709: 3704: 3699: 3694: 3689: 3684: 3679: 3674: 3669: 3664: 3659: 3654: 3649: 3644: 3639: 3634: 3629: 3624: 3619: 3614: 3609: 3601: 3593: 3585: 3580: 3575: 3570: 3565: 3560: 3555: 3550: 3545: 3540: 3535: 3530: 3525: 3520: 3515: 3510: 3505: 3500: 3495: 3490: 3480: 3475: 3470: 3465: 3460: 3455: 3450: 3445: 3440: 3414: 3409: 3404: 3399: 3394: 3389: 3384: 3379: 3374: 3369: 3364: 3351: 3350: 3345: 3340: 3335: 3330: 3325: 3320: 3318:Spironolactone 3315: 3310: 3305: 3300: 3295: 3290: 3285: 3280: 3275: 3270: 3265: 3260: 3255: 3250: 3245: 3240: 3235: 3230: 3225: 3220: 3215: 3210: 3205: 3200: 3195: 3190: 3185: 3180: 3175: 3170: 3165: 3160: 3155: 3150: 3145: 3143:Cyproheptadine 3140: 3135: 3130: 3125: 3120: 3118:Canrenoic acid 3115: 3110: 3105: 3100: 3095: 3090: 3085: 3080: 3075: 3070: 3061: 3059: 3055: 3054: 3052: 3051: 3046: 3041: 3036: 3027: 3026: 3021: 3016: 3011: 3006: 3001: 2996: 2991: 2986: 2981: 2976: 2971: 2966: 2961: 2956: 2951: 2946: 2941: 2936: 2931: 2926: 2921: 2916: 2911: 2906: 2901: 2896: 2891: 2886: 2881: 2876: 2871: 2866: 2857: 2855: 2844: 2843: 2841: 2840: 2835: 2830: 2825: 2820: 2815: 2810: 2801: 2800: 2795: 2790: 2781: 2780: 2775: 2766: 2765: 2760: 2759: 2758: 2748: 2746:Norgestrienone 2743: 2738: 2724: 2722:Norethisterone 2719: 2718: 2717: 2707: 2697: 2695:Levonorgestrel 2692: 2687: 2682: 2681: 2680: 2670: 2665: 2660: 2651: 2650: 2645: 2640: 2631: 2630: 2625: 2624: 2623: 2613: 2604: 2603: 2594: 2593: 2584: 2583: 2578: 2569: 2568: 2563: 2558: 2553: 2548: 2543: 2538: 2533: 2528: 2523: 2518: 2516:Ethyldienolone 2513: 2508: 2503: 2494: 2493: 2488: 2483: 2478: 2473: 2468: 2463: 2458: 2457: 2456: 2451: 2441: 2436: 2431: 2426: 2421: 2419:Androisoxazole 2412: 2411: 2406: 2401: 2396: 2395: 2394: 2379: 2374: 2373: 2372: 2367: 2362: 2357: 2347: 2342: 2337: 2332: 2327: 2322: 2317: 2312: 2307: 2302: 2297: 2288: 2287: 2282: 2277: 2268: 2267: 2266: 2265: 2260: 2250: 2245: 2244: 2243: 2238: 2233: 2228: 2218: 2217: 2216: 2206: 2201: 2200: 2199: 2189: 2188: 2187: 2177: 2172: 2159: 2158: 2157: 2152: 2147: 2137: 2132: 2127: 2122: 2117: 2116: 2115: 2105: 2100: 2095: 2090: 2089: 2088: 2078: 2069: 2068: 2063: 2062: 2061: 2051: 2046: 2045: 2044: 2034: 2032:Methyldiazinol 2029: 2028: 2027: 2017: 2012: 2007: 2002: 1997: 1996: 1995: 1985: 1984: 1983: 1968: 1963: 1958: 1953: 1952: 1951: 1941: 1936: 1931: 1926: 1921: 1916: 1914:1-Testosterone 1911: 1906: 1901: 1892: 1891: 1890: 1889: 1884: 1869: 1864: 1859: 1854: 1849: 1844: 1843: 1842: 1837: 1827: 1822: 1821: 1820: 1810: 1809: 1808: 1803: 1798: 1788: 1783: 1782: 1781: 1771: 1766: 1761: 1760: 1759: 1754: 1749: 1744: 1734: 1729: 1724: 1719: 1714: 1709: 1704: 1699: 1690: 1688: 1681: 1670: 1669: 1661: 1659: 1658: 1651: 1644: 1636: 1627: 1626: 1624: 1623: 1618: 1613: 1608: 1603: 1598: 1597: 1596: 1595: 1592: 1581: 1575: 1569: 1568: 1565: 1564: 1561: 1560: 1558: 1557: 1552: 1543: 1541: 1537: 1536: 1534: 1533: 1503: 1493: 1483: 1480:paroxypropione 1449: 1442:chlorpromazine 1430:metoclopramide 1412: 1407: 1405: 1399: 1398: 1395: 1394: 1392: 1391: 1389:Spironolactone 1386: 1381: 1376: 1371: 1366: 1361: 1356: 1351: 1342: 1340: 1336: 1335: 1333: 1332: 1327: 1322: 1317: 1312: 1306: 1304: 1295: 1287: 1286: 1284: 1283: 1278: 1273: 1268: 1263: 1258: 1253: 1248: 1243: 1238: 1229: 1228: 1226:Spironolactone 1223: 1218: 1213: 1208: 1203: 1198: 1193: 1188: 1183: 1178: 1173: 1168: 1163: 1151: 1149: 1132: 1126: 1125: 1122: 1121: 1119: 1118: 1094: 1080: 1065: 1063: 1057: 1056: 1054: 1053: 1044: 1043: 1038: 1035:norgestrienone 1019:levonorgestrel 1008: 1003: 994: 993: 984: 983: 978: 973: 968: 963: 954: 953: 948: 943: 938: 933: 928: 923: 921:Androisoxazole 914: 913: 908: 903: 898: 893: 888: 883: 878: 873: 868: 863: 858: 853: 848: 843: 834: 833: 828: 823: 818: 813: 808: 794: 785: 784: 779: 774: 769: 764: 759: 754: 749: 744: 739: 730: 729: 687: 682: 677: 672: 667: 662: 657: 652: 647: 642: 637: 632: 623: 621: 604: 587: 586: 577: 575: 574: 567: 560: 552: 544: 543: 500: 456: 441: 428: 427: 425: 422: 349: 346: 345: 340: 336:standard state 333: 330: 329: 323: 317: 316: 313: 307: 301: 295: 290: 285: 282: 281: 277: 276: 274: 273: 270: 262: 261: 260: 257: 256: 254: 253: 249: 248: 240: 239: 238: 235: 234: 232: 231: 223: 221: 215: 214: 212: 211: 203: 201: 193: 190: 189: 187: 186: 178: 176: 170: 169: 167: 166: 158: 156: 150: 149: 147: 146: 138: 136: 130: 129: 127: 126: 118: 116: 110: 109: 107: 106: 98: 96: 89: 86: 85: 83: 82: 74: 72: 67: 64: 63: 59: 58: 55: 51: 50: 39: 33: 32: 28: 27: 13: 10: 9: 6: 4: 3: 2: 3969: 3958: 3955: 3953: 3950: 3948: 3945: 3943: 3940: 3938: 3935: 3933: 3930: 3928: 3925: 3924: 3922: 3907: 3904: 3902: 3899: 3897: 3894: 3892: 3889: 3887: 3884: 3881: 3880: 3877: 3867: 3864: 3859: 3854: 3852: 3849: 3846: 3839: 3832: 3825: 3819: 3817: 3814: 3812: 3809: 3807: 3804: 3801: 3797: 3793: 3789: 3785: 3781: 3777: 3774: 3773: 3771: 3767: 3764: 3762: 3758: 3748: 3745: 3743: 3740: 3738: 3735: 3733: 3730: 3728: 3727:Valproic acid 3725: 3723: 3720: 3718: 3715: 3713: 3710: 3708: 3705: 3703: 3700: 3698: 3695: 3693: 3690: 3688: 3685: 3683: 3680: 3678: 3675: 3673: 3672:Rezvilutamide 3670: 3668: 3665: 3663: 3660: 3658: 3655: 3653: 3650: 3648: 3647:Proxalutamide 3645: 3643: 3640: 3638: 3635: 3633: 3630: 3628: 3625: 3623: 3620: 3618: 3615: 3613: 3610: 3608: 3606: 3602: 3600: 3598: 3594: 3592: 3590: 3586: 3584: 3581: 3579: 3576: 3574: 3571: 3569: 3566: 3564: 3561: 3559: 3556: 3554: 3551: 3549: 3546: 3544: 3541: 3539: 3536: 3534: 3531: 3529: 3526: 3524: 3521: 3519: 3516: 3514: 3511: 3509: 3506: 3504: 3501: 3499: 3496: 3494: 3491: 3488: 3484: 3481: 3479: 3476: 3474: 3471: 3469: 3466: 3464: 3461: 3459: 3456: 3454: 3451: 3449: 3446: 3444: 3441: 3438: 3434: 3430: 3426: 3422: 3418: 3415: 3413: 3410: 3408: 3405: 3403: 3400: 3398: 3395: 3393: 3390: 3388: 3385: 3383: 3380: 3378: 3375: 3373: 3370: 3368: 3365: 3363: 3362:-Bicalutamide 3361: 3356: 3355:Nonsteroidal: 3353: 3352: 3349: 3346: 3344: 3341: 3339: 3336: 3334: 3331: 3329: 3326: 3324: 3321: 3319: 3316: 3314: 3311: 3309: 3306: 3304: 3301: 3299: 3296: 3294: 3291: 3289: 3286: 3284: 3281: 3279: 3276: 3274: 3271: 3269: 3266: 3264: 3261: 3259: 3256: 3254: 3251: 3249: 3246: 3244: 3241: 3239: 3236: 3234: 3231: 3229: 3226: 3224: 3223:Guggulsterone 3221: 3219: 3216: 3214: 3211: 3209: 3206: 3204: 3201: 3199: 3196: 3194: 3191: 3189: 3186: 3184: 3181: 3179: 3176: 3174: 3171: 3169: 3166: 3164: 3161: 3159: 3156: 3154: 3151: 3149: 3146: 3144: 3141: 3139: 3136: 3134: 3131: 3129: 3126: 3124: 3121: 3119: 3116: 3114: 3111: 3109: 3106: 3104: 3101: 3099: 3096: 3094: 3091: 3089: 3086: 3084: 3081: 3079: 3076: 3074: 3071: 3069: 3066: 3063: 3062: 3060: 3056: 3050: 3047: 3045: 3042: 3040: 3037: 3035: 3032: 3029: 3028: 3025: 3022: 3020: 3017: 3015: 3012: 3010: 3007: 3005: 3002: 3000: 2997: 2995: 2992: 2990: 2987: 2985: 2982: 2980: 2977: 2975: 2972: 2970: 2967: 2965: 2962: 2960: 2957: 2955: 2952: 2950: 2947: 2945: 2942: 2940: 2937: 2935: 2932: 2930: 2927: 2925: 2922: 2920: 2917: 2915: 2912: 2910: 2907: 2905: 2902: 2900: 2897: 2895: 2892: 2890: 2887: 2885: 2882: 2880: 2877: 2875: 2872: 2870: 2867: 2865: 2862: 2861:Nonsteroidal: 2859: 2858: 2856: 2851: 2845: 2839: 2836: 2834: 2831: 2829: 2826: 2824: 2821: 2819: 2816: 2814: 2813:5α-Androstane 2811: 2809: 2806: 2803: 2802: 2799: 2796: 2794: 2791: 2789: 2786: 2783: 2782: 2779: 2776: 2774: 2771: 2768: 2767: 2764: 2761: 2757: 2754: 2753: 2752: 2749: 2747: 2744: 2742: 2739: 2736: 2732: 2728: 2725: 2723: 2720: 2716: 2713: 2712: 2711: 2708: 2705: 2701: 2698: 2696: 2693: 2691: 2688: 2686: 2683: 2679: 2676: 2675: 2674: 2671: 2669: 2666: 2664: 2661: 2659: 2656: 2653: 2652: 2649: 2646: 2644: 2641: 2639: 2636: 2633: 2632: 2629: 2626: 2622: 2621:Ethandrostate 2619: 2618: 2617: 2614: 2612: 2609: 2606: 2605: 2602: 2599: 2596: 2595: 2592: 2589: 2586: 2585: 2582: 2579: 2577: 2574: 2571: 2570: 2567: 2564: 2562: 2559: 2557: 2554: 2552: 2549: 2547: 2544: 2542: 2539: 2537: 2534: 2532: 2529: 2527: 2524: 2522: 2521:Ethylestrenol 2519: 2517: 2514: 2512: 2509: 2507: 2504: 2502: 2499: 2496: 2495: 2492: 2489: 2487: 2484: 2482: 2479: 2477: 2474: 2472: 2469: 2467: 2464: 2462: 2459: 2455: 2452: 2450: 2447: 2446: 2445: 2442: 2440: 2437: 2435: 2432: 2430: 2427: 2425: 2422: 2420: 2417: 2414: 2413: 2410: 2407: 2405: 2402: 2400: 2397: 2393: 2390: 2389: 2387: 2383: 2380: 2378: 2375: 2371: 2368: 2366: 2363: 2361: 2358: 2356: 2353: 2352: 2351: 2348: 2346: 2343: 2341: 2338: 2336: 2333: 2331: 2328: 2326: 2323: 2321: 2318: 2316: 2313: 2311: 2308: 2306: 2303: 2301: 2298: 2296: 2293: 2290: 2289: 2286: 2283: 2281: 2278: 2276: 2273: 2270: 2269: 2264: 2261: 2259: 2256: 2255: 2254: 2251: 2249: 2246: 2242: 2239: 2237: 2234: 2232: 2229: 2227: 2224: 2223: 2222: 2219: 2215: 2212: 2211: 2210: 2207: 2205: 2202: 2198: 2195: 2194: 2193: 2190: 2186: 2183: 2182: 2181: 2178: 2176: 2173: 2171: 2169: 2165: 2160: 2156: 2153: 2151: 2148: 2146: 2143: 2142: 2141: 2138: 2136: 2133: 2131: 2128: 2126: 2123: 2121: 2118: 2114: 2111: 2110: 2109: 2106: 2104: 2101: 2099: 2096: 2094: 2091: 2087: 2084: 2083: 2082: 2079: 2077: 2074: 2071: 2070: 2067: 2064: 2060: 2057: 2056: 2055: 2052: 2050: 2047: 2043: 2040: 2039: 2038: 2035: 2033: 2030: 2026: 2023: 2022: 2021: 2018: 2016: 2013: 2011: 2008: 2006: 2003: 2001: 1998: 1994: 1991: 1990: 1989: 1986: 1982: 1979: 1978: 1976: 1972: 1969: 1967: 1964: 1962: 1959: 1957: 1954: 1950: 1947: 1946: 1945: 1942: 1940: 1937: 1935: 1932: 1930: 1927: 1925: 1922: 1920: 1917: 1915: 1912: 1910: 1907: 1905: 1902: 1900: 1897: 1894: 1893: 1888: 1885: 1883: 1880: 1879: 1877: 1873: 1870: 1868: 1865: 1863: 1860: 1858: 1855: 1853: 1850: 1848: 1845: 1841: 1838: 1836: 1833: 1832: 1831: 1828: 1826: 1823: 1819: 1816: 1815: 1814: 1811: 1807: 1804: 1802: 1799: 1797: 1794: 1793: 1792: 1789: 1787: 1784: 1780: 1777: 1776: 1775: 1772: 1770: 1767: 1765: 1762: 1758: 1755: 1753: 1750: 1748: 1745: 1743: 1740: 1739: 1738: 1735: 1733: 1730: 1728: 1725: 1723: 1720: 1718: 1715: 1713: 1710: 1708: 1705: 1703: 1700: 1698: 1695: 1692: 1691: 1689: 1685: 1682: 1677: 1671: 1667: 1664: 1657: 1652: 1650: 1645: 1643: 1638: 1637: 1634: 1622: 1619: 1617: 1614: 1612: 1609: 1607: 1604: 1601: 1600: 1593: 1591: 1588: 1587: 1585: 1582: 1579: 1576: 1574: 1571: 1570: 1566: 1556: 1553: 1551: 1548: 1545: 1544: 1542: 1538: 1531: 1527: 1523: 1519: 1515: 1511: 1507: 1504: 1501: 1497: 1494: 1491: 1487: 1486:GnRH agonists 1484: 1481: 1477: 1473: 1469: 1465: 1461: 1457: 1453: 1450: 1447: 1443: 1439: 1435: 1431: 1427: 1423: 1419: 1416: 1409: 1408: 1406: 1404: 1400: 1390: 1387: 1385: 1382: 1380: 1377: 1375: 1372: 1370: 1367: 1365: 1362: 1360: 1357: 1355: 1352: 1350: 1347: 1344: 1343: 1341: 1337: 1331: 1328: 1326: 1323: 1321: 1318: 1316: 1313: 1311: 1308: 1307: 1305: 1303: 1299: 1296: 1294: 1288: 1282: 1279: 1277: 1274: 1272: 1269: 1267: 1264: 1262: 1259: 1257: 1254: 1252: 1249: 1247: 1244: 1242: 1239: 1237: 1234: 1233:Nonsteroidal: 1231: 1230: 1227: 1224: 1222: 1219: 1217: 1214: 1212: 1209: 1207: 1204: 1202: 1199: 1197: 1194: 1192: 1189: 1187: 1184: 1182: 1179: 1177: 1174: 1172: 1169: 1167: 1164: 1162: 1159: 1156: 1153: 1152: 1150: 1148: 1142: 1136: 1133: 1131: 1130:Antiandrogens 1127: 1113: 1104: 1098: 1097:Gonadotropins 1095: 1092: 1088: 1084: 1083:GnRH agonists 1081: 1078: 1074: 1070: 1069:Antiestrogens 1067: 1066: 1064: 1062: 1058: 1052: 1049: 1046: 1045: 1042: 1039: 1036: 1032: 1028: 1024: 1020: 1016: 1012: 1009: 1007: 1004: 1002: 999: 996: 995: 992: 989: 986: 985: 982: 979: 977: 974: 972: 969: 967: 964: 962: 961:Ethylestrenol 959: 956: 955: 952: 949: 947: 944: 942: 939: 937: 934: 932: 929: 927: 924: 922: 919: 916: 915: 912: 909: 907: 904: 902: 899: 897: 894: 892: 889: 887: 884: 882: 879: 877: 874: 872: 869: 867: 864: 862: 859: 857: 854: 852: 849: 847: 844: 842: 839: 836: 835: 832: 829: 827: 824: 822: 819: 817: 814: 812: 809: 806: 802: 798: 795: 793: 790: 787: 786: 783: 780: 778: 775: 773: 770: 768: 765: 763: 760: 758: 755: 753: 750: 748: 745: 743: 740: 738: 735: 732: 731: 727: 723: 719: 715: 711: 707: 703: 699: 695: 691: 688: 686: 683: 681: 678: 676: 673: 671: 668: 666: 663: 661: 658: 656: 653: 651: 648: 646: 643: 641: 638: 636: 633: 631: 628: 625: 624: 622: 620: 614: 608: 605: 599: 592: 588: 584: 583:antiandrogens 580: 573: 568: 566: 561: 559: 554: 553: 550: 539: 535: 531: 527: 523: 519: 516:(9): 1241–6. 515: 511: 504: 501: 496: 492: 488: 484: 480: 476: 472: 468: 460: 457: 452: 445: 442: 438: 433: 430: 423: 421: 419: 415: 411: 406: 402: 399: 396: 391: 389: 385: 381: 378: 374: 370: 366: 363: 359: 355: 343: 337: 331: 324: 322: 319: 318: 291: 288: 284: 283: 278: 269: 265: 258: 247: 243: 236: 229: 225: 224: 222: 220: 217: 216: 209: 205: 204: 202: 196: 192: 191: 184: 180: 179: 177: 175: 172: 171: 164: 160: 159: 157: 155: 152: 151: 144: 143:ChEMBL1921976 140: 139: 137: 135: 132: 131: 124: 120: 119: 117: 115: 112: 111: 104: 100: 99: 97: 93: 88: 87: 80: 76: 75: 73: 70: 66: 65: 60: 52: 47: 43: 38: 34: 29: 25: 20: 3947:Naphthalenes 3932:Carboxamides 3866:Testosterone 3652:Pyrilutamide 3604: 3596: 3588: 3553:Lavender oil 3543:Ketoconazole 3508:Enzalutamide 3478:Darolutamide 3412:Bicalutamide 3387:Atraric acid 3359: 3354: 3338:Trimegestone 3293:Promegestone 3258:Mifepristone 3233:Medrogestone 3178:Drospirenone 3133:Clascoterone 3064: 3030: 2974:JNJ-37654032 2969:JNJ-28330835 2964:JNJ-26146900 2860: 2804: 2784: 2769: 2751:Quingestanol 2668:Etonogestrel 2654: 2634: 2607: 2597: 2587: 2572: 2556:Propetandrol 2497: 2486:Oxymetholone 2461:Methasterone 2415: 2409:Tiomesterone 2399:Oxymesterone 2291: 2271: 2192:Norclostebol 2167: 2163: 2072: 2010:Mepitiostane 2005:Epitiostanol 1988:Drostanolone 1939:Androsterone 1895: 1876:+dutasteride 1872:Testosterone 1840:DHEA sulfate 1693: 1546: 1506:Progestogens 1374:Ketoconazole 1302:5α-Reductase 1266:Ketoconazole 1256:Enzalutamide 1251:Darolutamide 1241:Bicalutamide 1232: 1196:Medrogestone 1191:Drospirenone 1154: 1047: 997: 987: 957: 946:Oxymetholone 917: 901:Oxymesterone 837: 811:Norclostebol 788: 762:Mepitiostane 757:Epitiostanol 733: 685:Testosterone 626: 513: 509: 503: 470: 466: 459: 444: 432: 418:testosterone 398:biosynthesis 392: 362:nonsteroidal 357: 353: 352: 123:CHEBI:231353 62:Identifiers 54:Other names 45: 41: 3851:Osteocalcin 3732:Vinclozolin 3717:Thalidomide 3712:Seviteronel 3642:Procymidone 3578:Masofaniten 3533:Inocoterone 3437:bisphenol S 3433:bisphenol F 3429:bisphenol A 3407:BAY-1024767 3382:Apalutamide 3328:Spiroxasone 3323:Spirorenone 3303:Rosterolone 3243:Mespirenone 3188:Edogestrone 3158:Delanterone 3148:Cyproterone 3138:Clometerone 3108:Benorterone 3093:Abiraterone 3058:Antagonists 2989:PF-06260414 2894:BMS-564,929 2818:Alternariol 2710:Lynestrenol 2663:Desogestrel 2546:Norboletone 2536:Metribolone 2481:Oxandrolone 2439:Mestanolone 2404:Penmesterol 2335:Formebolone 2300:Calusterone 2295:Bolasterone 2049:Prostanozol 2020:Mesterolone 1580:from market 1490:leuprorelin 1438:haloperidol 1434:risperidone 1426:domperidone 1418:antagonists 1384:Seviteronel 1325:Finasteride 1320:Epristeride 1315:Dutasteride 1310:Alfatradiol 1276:Seviteronel 1236:Apalutamide 1147:antagonists 1091:leuprorelin 1031:lynestrenol 941:Oxandrolone 936:Mestanolone 906:Penmesterol 861:Formebolone 846:Calusterone 841:Bolasterone 767:Mesterolone 714:Deposterona 412:(DHEA) and 280:Properties 79:566939-85-3 3921:Categories 3845:-ornithine 3788:gadolinium 3637:Prochloraz 3632:Phenothrin 3612:Nilutamide 3583:Methiocarb 3503:Endosulfan 3468:Cioteronel 3463:Cimetidine 3453:BMS-641988 3448:BMS-570511 3443:BMS-501949 3417:Bisphenols 3372:Antarlides 3348:Zanoterone 3283:Oxendolone 3228:Ludaterone 3218:Galeterone 3168:Dicirenone 3065:Steroidal: 3031:Steroidal: 3024:Vosilasarm 2919:GSK2881078 2874:AC-262,536 2833:Trilostane 2741:Norgestrel 2690:Gestrinone 2658:Δ-Tibolone 2541:Mibolerone 2491:Stanozolol 2444:Metenolone 2221:Trenbolone 2180:Nandrolone 2130:Dienedione 2054:Stenbolone 2015:Mesabolone 1867:Silandrone 1862:Quinbolone 1857:Plomestane 1852:Formestane 1847:Exemestane 1769:Atamestane 1666:modulators 1500:cetrorelix 1456:bifluranol 1379:Nilutamide 1359:Bifluranol 1349:+niraparib 1293:inhibitors 1271:Nilutamide 1246:Cimetidine 1216:Oxendolone 1161:+niraparib 1155:Steroidal: 1023:norgestrel 1011:Progestins 1006:Gestrinone 966:Mibolerone 951:Stanozolol 680:Quinbolone 424:References 384:metastatic 321:Molar mass 228:UE5K2FNS92 154:ChemSpider 90:3D model ( 69:CAS Number 37:IUPAC name 17:Orteronel 3831:-arginine 3816:Estradiol 3796:strontium 3792:magnesium 3780:aluminium 3747:YM-175735 3682:Ro 5-2537 3677:Ro 2-7239 3627:PF-998425 3622:Pentomone 3563:LG-120907 3523:Flutamide 3518:Fenarimol 3458:CH5137291 3397:Bakuchiol 3333:Topterone 3298:Prorenone 3273:Osaterone 3268:Nordinone 3253:Mexrenone 3173:Dienogest 3123:Canrenone 3044:TFM-4AS-1 2984:ORM-11984 2924:GSK-4336A 2914:GLPG-0492 2838:ZM-182345 2685:Gestodene 2673:Etynodiol 2429:Furazabol 2320:Enestebol 2248:Trendione 2209:Oxabolone 2135:Dienolone 2108:Bolandiol 2037:Nisterime 1791:Clostebol 1774:Boldenone 1590:Phase III 1578:Withdrawn 1464:estradiol 1452:Estrogens 1446:sulpiride 1424:) (e.g., 1369:Flutamide 1261:Flutamide 1186:Dienogest 1166:Canrenone 1077:clomifene 1073:tamoxifen 926:Furazabol 640:Clostebol 591:Androgens 579:Androgens 401:inhibitor 377:phase III 354:Orteronel 3882:See also 3769:Agonists 3742:YM-92088 3707:RU-58841 3702:RU-58642 3697:RU-57073 3692:RU-56187 3687:RU-22930 3617:ONC1-13B 3568:LGD-1331 3493:Dieldrin 3487:p,p’-DDE 3392:AZD-3514 3377:Arabilin 3308:RU-15328 3248:Metogest 3183:DU-41165 3019:S-101479 2999:RU-59063 2954:LGD-4033 2949:LGD-3303 2939:LGD-2226 2929:GSK-8698 2828:Drupanol 2823:Cl-4AS-1 2763:Tibolone 1944:Bolazine 1687:Agonists 1602:See also 1508:(incl., 1415:receptor 1041:Tibolone 722:Sustanon 718:Omnadren 619:agonists 538:36575315 530:16287438 495:20204862 487:22249003 395:androgen 3838:-lysine 3826:(incl. 3784:calcium 3778:(incl. 3776:Cations 3573:Linuron 3513:EPI-001 3419:(e.g., 3208:EM-6537 3203:EM-5855 3198:EM-5854 3193:EM-4350 3039:MK-0773 3034:EM-9017 3014:S-40503 2869:ACP-105 2864:198RL26 2729:(e.g., 2702:(e.g., 2611:Danazol 2561:RU-2309 2501:Bolenol 1498:(e.g., 1488:(e.g., 1454:(e.g., 1099:(e.g., 1085:(e.g., 1071:(e.g., 1013:(e.g., 1001:Danazol 799:(e.g., 692:(e.g., 594:(incl. 510:BJU Int 405:CYP17A1 360:) is a 358:TAK-700 326:307.353 208:9883029 195:PubChem 163:8058704 56:TAK-700 3761:GPRC6A 3737:YM-580 3667:RD-162 3558:LG-105 2909:FTBU-1 1573:WHO-EM 1540:Others 1339:Others 536:  528:  493:  485:  264:SMILES 183:D10146 134:ChEMBL 31:Names 3425:BFDGE 3421:BADGE 3367:AA560 3049:YK-11 2959:LY305 2849:SARMs 534:S2CID 491:S2CID 242:InChI 114:ChEBI 92:JSmol 3857:SHBG 3800:zinc 3498:DIMP 3113:BOMT 3009:S-23 2899:DTIB 581:and 526:PMID 483:PMID 382:for 219:UNII 174:KEGG 3483:DDT 3004:S-1 2994:R-1 1111:hCG 597:AAS 518:doi 475:doi 471:129 198:CID 3923:: 3840:, 3833:, 3798:, 3794:, 3790:, 3786:, 3782:, 3435:, 3431:, 3427:, 3423:, 2733:, 2388:) 1977:) 1878:) 1675:AR 1586:: 1528:, 1524:, 1520:, 1516:, 1512:, 1478:, 1474:, 1470:, 1466:, 1462:, 1458:, 1444:, 1440:, 1436:, 1432:, 1428:, 1140:AR 1108:, 1102:LH 1089:, 1075:, 1033:, 1029:, 1025:, 1021:, 1017:, 803:, 728:)) 724:, 720:, 716:, 708:, 704:, 700:, 696:, 612:AR 532:. 524:. 514:96 512:. 489:. 481:. 469:. 420:. 386:, 302:17 296:18 3847:) 3843:L 3836:L 3829:L 3822:L 3802:) 3605:N 3597:N 3589:N 3489:) 3439:) 3360:N 3358:5 2737:) 2706:) 2384:( 2168:N 2164:N 1973:( 1874:( 1655:e 1648:t 1641:v 1532:) 1502:) 1492:) 1482:) 1448:) 1420:( 1413:2 1411:D 1117:) 1093:) 1079:) 1037:) 807:) 712:( 603:) 571:e 564:t 557:v 540:. 520:: 497:. 477:: 453:. 356:( 314:2 311:O 308:3 305:N 299:H 293:C 94:) 46:N 42:H

Index


IUPAC name
CAS Number
566939-85-3
JSmol
Interactive image
ChEBI
CHEBI:231353
ChEMBL
ChEMBL1921976
ChemSpider
8058704
KEGG
D10146
PubChem
9883029
UNII
UE5K2FNS92
InChI
SMILES
Chemical formula
Molar mass
standard state
Infobox references
nonsteroidal
CYP17A1 inhibitor
Takeda Pharmaceutical Company
Millennium Pharmaceuticals
phase III
clinical trials

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