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Autotransplantation

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54: 356:(iPSCs), capable of differentiating into any cell type, have potential for solving the problem of donor organ shortage. Reprogramming technology would be used to obtain a personalized, patient-specific, cell product without problems related to histocompatibility of the transplanted tissues and organs. However, the ability to generate such tissues and organs will depend on successful strategies to overcome immunogenicity of the manipulated product. 282: 341:
liver resection and autotransplantation is used in the treatment of selected cases of conventionally unresectable hepatic tumors. It can also be implemented in rare scenarios of a blunt abdominal trauma. Kidney autotransplantation is a method of a nephron-sparing renal tumor excision or complex renal
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refers to a blood donation marked for use by the donor, typically for a scheduled surgery. (Generally, the notion of "donation" does not refer to giving to oneself, though in this context it has become somewhat acceptably idiomatic.) They are commonly called "autos" by blood bank personnel, and it is
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There is also a risk that, in an emergency or if more blood is required than has been set aside in advance, the patient could still be exposed to donor blood instead of autologous blood. Autologous donation is also not suitable for patients who are medically unable to or advised not to give blood,
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and synthetic graft materials are often used as alternatives. Autografts have long been considered the "Gold Standard" in oral surgery and implant dentistry because it offered the best regeneration results. Lately, the introduction of morphogen-enhanced bone graft substitutes have shown similar
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Andreasen JO, Paulsen HU, Yu Z, Ahlquist R, Bayer T, Schwartz O (February 1990). "A long-term study of 370 autotransplanted premolars. Part I. Surgical procedures and standardized techniques for monitoring healing".
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can be sourced from a patient's own bone in order to fill space and produce an osteogenic response in a bone defect. However, due to the donor-site morbidity associated with autograft, other methods such as bone
171:, or skin, can be used for a wide variety of organs. One of the rare examples is autotransplantation of a kidney from one side of the body to the other. Kidney autotransplantation is used as a treatment for 512:
Harlaar, JJ; Gosselink, MP; Hop, WC; Lange, JF; Busch, OR; Jeekel, H (November 2012). "Blood transfusions and prognosis in colorectal cancer: long-term results of a randomized controlled trial".
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A common example is the removal of a piece of bone (usually from the hip) and its being ground into a paste for the reconstruction of another portion of bone.
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Boggi, Ugo; Vistoli, Fabio; Del Chiaro, Marco; Signori, Stefano; Sgambelluri, Francesco; Roncella, Manuela; Filipponi, Franco; Mosca, Franco (February 2006).
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Bogomiakova ME, Bogomazova AN, Lagarkova MA (May 2024). "Dysregulation of Immune Tolerance to Autologous iPSCs and Their Differentiated Derivatives".
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Janssen, Martin W. W.; Linxweiler, Johannes; Philipps, Ines; Bütow, Zentia; Siemer, Stefan; Stöckle, Michael; Ohlmann, Carsten-Henning (2018-02-20).
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collection following mobilization of stem cells from the bone marrow into the peripheral blood. This is typically used for treatment of
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Blood donation prior to colorectal cancer surgery seemed causative for a worse overall and colorectal cancer specific survival.
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antibodies. In the United States, autologous blood is tested only if it is collected in one place and shipped to another.
1998: 1852: 1301: 1228: 746:"Kidney autotransplantation after nephrectomy and work bench surgery as an ultimate approach to nephron-sparing surgery" 203: 184: 31: 1868: 1306: 1311: 1167: 1089: 309: 1059: 805:"Repair of complex renal artery aneurysms by laparoscopic nephrectomy with ex vivo repair and autotransplantation" 2078: 2073: 2038: 2018: 1973: 1915: 1654: 1193: 1064: 1885: 1895: 1258: 1084: 168: 64: 556: 347: 2043: 2192: 2143: 2123: 1770: 1425: 1370: 1121: 1029: 157:
transplantation (grafts transplanted between two genetically identical individuals of the same species) and
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surgery followed by autotransplantation were reported also for heart, lungs and intestines, including
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In most cases, the blood is discarded if it is not used instead of being added to the general supply.
650:"Outcomes of ex vivo liver resection and autotransplantation: A systematic review and meta-analysis" 2103: 2093: 1743: 1539: 1034: 996: 979: 224:
If only autologous blood is used during surgery the risk of exposure to infectious disease such as
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Gallagher, Katherine A.; Phelan, Michael W.; Stern, Tina; Bartlett, Stephen T. (December 2008).
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Zawistowski, Michał; Nowaczyk, Joanna; Jakubczyk, Michał; Domagała, Piotr (October 2020).
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success rates and quality of regeneration; however, their price is still very high.
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Autologous blood is not routinely tested for infectious diseases markers such as
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Higher cost due to individualized processing, record-keeping, and management.
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after collection for infusion after the patient undergoes high-dose
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involves harvesting peripheral blood mononuclear cells (PBMCs) by
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Surgically moving tissue to a different part of the same body
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Autotransplantation of selected organs is often preceded by
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Autotransplantation, although most common with blood, bone,
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The Journal of Trauma: Injury, Infection, and Critical Care
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from one part of the body to another in the same person (
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Regina Hwang; Peter Liou; Tomoaki Kato (November 2018).
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tissue) transplanted by such a procedure is called an
37:"autologous" redirects here. Not to be confused with 1972: 1904: 1861: 1822: 1786: 1707: 1612: 1564: 1548: 1532: 1501: 1475: 1439: 1403: 1396: 1351: 1325: 1277: 1212: 1186: 1158: 1130: 1005: 972: 63: 46: 209:Some advantages of autologous blood donation are: 1931:Transfusion-associated graft versus host disease 213:Blood type will always match, even with a rare 1600:List of organ transplant donors and recipients 198:one major form of the more general concept of 1681: 950: 291:Bone grafting § Autologous bone grafting 153:(from other individual of the same species), 8: 1199:Post-transplant lymphoproliferative disorder 1926:Transfusion associated circulatory overload 360:Hematopoietic stem cell autotransplantation 1936:Febrile non-hemolytic transfusion reaction 1809:International Society of Blood Transfusion 1688: 1674: 1666: 1400: 957: 943: 935: 887:StrĂĽĂźmann T, Marks R, Wäsch R (May 2024). 599:Ciubotaru, Anatol; Haverich, Axel (2015). 52: 914: 904: 820: 779: 761: 665: 616: 572: 342:artery aneurysm management. The uses of 280: 493:Boodman, Sandra D. (October 24, 2020). 428: 594: 592: 43: 1921:Transfusion related acute lung injury 285:Illustration depicting bone autograft 7: 365:Autologous stem-cell transplantation 30:For other uses of "autogenous", see 1343:Canadian Society of Transplantation 1338:American Society of Transplantation 76: 58:Autotransplantation of wisdom tooth 750:World Journal of Surgical Oncology 25: 1964:Transfusion transmitted infection 715:10.1097/01.ta.0000203562.90036.05 1269:United Network for Organ Sharing 1254:National Transplant Organization 1383:Organ transplantation in Israel 2219:Orthopedic surgical procedures 1388:Organ transplantation in Japan 1359:Organ transplantation in China 1333:American Society of Nephrology 437:"Definition of auto- in Greek" 354:Induced pluripotent stem cells 1: 1264:Trillium Gift of Life Network 1244:National Marrow Donor Program 1853:Intraoperative blood salvage 1302:Halachic Organ Donor Society 1229:Gift of Life Marrow Registry 526:10.1097/SLA.0b013e318271cedf 204:intraoperative blood salvage 185:Intraoperative blood salvage 1869:Blood compatibility testing 1307:Kidney Foundation of Canada 809:Journal of Vascular Surgery 310:bone morphogenetic proteins 2240: 1364:harvesting from Falun Gong 1312:National Kidney Foundation 1168:Non-heart-beating donation 667:10.1016/j.surg.2020.05.036 605:European Surgical Research 585:– via Plum xMetrics. 574:10.1016/j.jhep.2018.09.005 288: 182: 36: 29: 1916:Transfusion hemosiderosis 1595: 1194:Graft-versus-host disease 866:10.1134/S0006297924050031 822:10.1016/j.jvs.2008.07.015 763:10.1186/s12957-018-1338-1 317:Organ autotransplantation 232:from blood is eliminated. 179:Autologous blood donation 77: 51: 18:Autologous blood donation 2224:Transplantation medicine 1896:Monocyte monolayer assay 1259:NHS Blood and Transplant 337:) surgery. For example, 193:terminology, autologous 169:hematopoietic stem cells 1771:Granulocyte transfusion 1635:Immunosuppressive drugs 1371:Organ donation in India 906:10.3390/cancers16111987 243:The disadvantages are: 1655:Frankenstein's monster 1650:Total body irradiation 1376:Gurgaon kidney scandal 1234:Human Tissue Authority 417:Stem cell fat grafting 412:Spleen transplantation 286: 161:(from other species). 149:It is contrasted with 1906:Transfusion reactions 1640:Lung allocation score 1577:Jean-Michel Dubernard 966:Organ transplantation 561:Journal of Hepatology 284: 239:reactions is reduced. 105:, or even particular 2214:Transfusion medicine 1886:Kleihauer–Betke test 1848:Exchange transfusion 1727:Platelet transfusion 1701:transfusion medicine 1447:J. Hartwell Harrison 1204:Transplant rejection 297:orthopaedic medicine 126:tissue (also called 1974:Blood group systems 1909:and adverse effects 1744:Fresh frozen plasma 1556:AndrĂ© van der Merwe 1540:Richard C. Lillehei 1213:Transplant networks 997:Xenotransplantation 992:Autotransplantation 980:Allotransplantation 854:Biochemistry (Mosc) 173:nutcracker syndrome 159:xenotransplantation 151:allotransplantation 91:Autotransplantation 47:Autotransplantation 1411:Christiaan Barnard 1007:Organs and tissues 472:10.1093/ejo/12.1.3 379:. Stem cells are 287: 269:patients or small 115:meaning "self" in 2201: 2200: 1778:Blood substitutes 1766:White blood cells 1697:Blood transfusion 1663: 1662: 1645:Machine perfusion 1625:Edmonton protocol 1620:Biomedical tissue 1608: 1607: 1519:Vladimir Demikhov 1421:Adrian Kantrowitz 1173:Organ procurement 618:10.1159/000367942 514:Annals of Surgery 202:(the other being 88: 87: 16:(Redirected from 2231: 1891:Antibody elution 1838:plateletpheresis 1804:Blood management 1787:General concepts 1690: 1683: 1676: 1667: 1467:Michael Woodruff 1401: 1132:Medical grafting 959: 952: 945: 936: 929: 928: 918: 908: 884: 878: 877: 849: 843: 842: 824: 800: 794: 793: 783: 765: 741: 735: 734: 694: 688: 687: 669: 645: 639: 638: 620: 596: 587: 586: 576: 552: 546: 545: 509: 503: 502: 490: 484: 483: 454: 448: 447: 445: 444: 439:. Dictionary.com 433: 373:multiple myeloma 81:edit on Wikidata 73: 56: 44: 21: 2239: 2238: 2234: 2233: 2232: 2230: 2229: 2228: 2204: 2203: 2202: 2197: 1992:Secretor status 1968: 1908: 1900: 1857: 1818: 1782: 1759:Cryosupernatant 1754:Cryoprecipitate 1734:Red blood cells 1703: 1694: 1664: 1659: 1604: 1591: 1560: 1544: 1528: 1497: 1471: 1452:John P. Merrill 1435: 1392: 1347: 1326:Joint societies 1321: 1292:Blood Cancer UK 1279: 1273: 1216: 1214: 1208: 1182: 1154: 1150:Vascular bypass 1126: 1001: 968: 963: 933: 932: 893:Cancers (Basel) 886: 885: 881: 851: 850: 846: 802: 801: 797: 743: 742: 738: 696: 695: 691: 647: 646: 642: 598: 597: 590: 554: 553: 549: 511: 510: 506: 499:Washington Post 492: 491: 487: 456: 455: 451: 442: 440: 435: 434: 430: 425: 397:Autotransfusion 393: 362: 319: 293: 279: 200:autotransfusion 187: 181: 95:transplantation 84: 69: 59: 42: 35: 28: 23: 22: 15: 12: 11: 5: 2237: 2235: 2227: 2226: 2221: 2216: 2206: 2205: 2199: 2198: 2196: 2195: 2190: 2185: 2180: 2175: 2170: 2165: 2160: 2151: 2146: 2141: 2136: 2131: 2126: 2121: 2116: 2111: 2106: 2101: 2091: 2086: 2081: 2076: 2071: 2066: 2061: 2056: 2051: 2046: 2041: 2036: 2031: 2026: 2021: 2016: 2011: 2006: 2001: 1996: 1995: 1994: 1984: 1978: 1976: 1970: 1969: 1967: 1966: 1961: 1959:Serum sickness 1956: 1955: 1954: 1949: 1938: 1933: 1928: 1923: 1918: 1912: 1910: 1902: 1901: 1899: 1898: 1893: 1888: 1883: 1878: 1877: 1876: 1874:Cross-matching 1865: 1863: 1859: 1858: 1856: 1855: 1850: 1845: 1834:plasmapheresis 1826: 1824: 1820: 1819: 1817: 1816: 1811: 1806: 1801: 1799:Blood donation 1796: 1790: 1788: 1784: 1783: 1781: 1780: 1775: 1774: 1773: 1763: 1762: 1761: 1756: 1751: 1746: 1736: 1731: 1730: 1729: 1719: 1713: 1711: 1709:Blood products 1705: 1704: 1695: 1693: 1692: 1685: 1678: 1670: 1661: 1660: 1658: 1657: 1652: 1647: 1642: 1637: 1632: 1627: 1622: 1616: 1614: 1613:Related topics 1610: 1609: 1606: 1605: 1603: 1602: 1596: 1593: 1592: 1590: 1589: 1584: 1579: 1574: 1568: 1566: 1562: 1561: 1559: 1558: 1552: 1550: 1546: 1545: 1543: 1542: 1536: 1534: 1530: 1529: 1527: 1526: 1524:James D. Hardy 1521: 1516: 1514:Joel D. Cooper 1511: 1505: 1503: 1499: 1498: 1496: 1495: 1490: 1488:James D. Hardy 1485: 1479: 1477: 1473: 1472: 1470: 1469: 1464: 1462:Elizabeth Ward 1459: 1454: 1449: 1443: 1441: 1437: 1436: 1434: 1433: 1431:Norman Shumway 1428: 1423: 1418: 1416:James D. Hardy 1413: 1407: 1405: 1398: 1394: 1393: 1391: 1390: 1385: 1380: 1379: 1378: 1368: 1367: 1366: 1355: 1353: 1349: 1348: 1346: 1345: 1340: 1335: 1329: 1327: 1323: 1322: 1320: 1319: 1314: 1309: 1304: 1299: 1294: 1289: 1283: 1281: 1275: 1274: 1272: 1271: 1266: 1261: 1256: 1251: 1246: 1241: 1236: 1231: 1226: 1224:Eurotransplant 1220: 1218: 1215:and government 1210: 1209: 1207: 1206: 1201: 1196: 1190: 1188: 1184: 1183: 1181: 1180: 1175: 1170: 1164: 1162: 1160:Organ donation 1156: 1155: 1153: 1152: 1147: 1142: 1136: 1134: 1128: 1127: 1125: 1124: 1119: 1114: 1109: 1104: 1099: 1094: 1093: 1092: 1082: 1077: 1072: 1067: 1062: 1057: 1052: 1047: 1042: 1037: 1032: 1027: 1022: 1017: 1011: 1009: 1003: 1002: 1000: 999: 994: 989: 988: 987: 976: 974: 970: 969: 964: 962: 961: 954: 947: 939: 931: 930: 879: 860:(5): 799–816. 844: 815:(6): 1408–13. 795: 736: 689: 660:(4): 631–642. 640: 611:(1–2): 64–74. 588: 567:(5): 1037–46. 547: 504: 485: 449: 427: 426: 424: 421: 420: 419: 414: 409: 407:Rotationplasty 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Retrieved 431: 402:Replantation 385:chemotherapy 363: 352: 350:approaches. 343: 338: 334: 330: 326: 322: 320: 294: 263: 256: 242: 235:The risk of 208: 188: 166: 163: 148: 143: 139: 135: 131: 127: 123: 121: 110: 90: 89: 1982:Blood types 1881:Coombs test 1717:Whole blood 1587:Bruce Reitz 1239:LifeSharers 1217:departments 1178:Organ trade 1020:Bone marrow 466:(1): 3–13. 39:autological 32:Autogenesis 2208:Categories 1794:Blood bank 1090:islet cell 1060:Heart–lung 443:2019-06-25 423:References 331:back-table 301:bone graft 289:See also: 215:blood type 183:See also: 132:autogeneic 128:autogenous 124:autologous 1999:Augustine 1943:reaction 1941:Hemolytic 1830:Apheresis 1722:Platelets 1352:Countries 1065:Intestine 831:0741-5214 772:1477-7819 756:(1): 35. 723:0022-5282 676:0039-6060 627:0014-312X 369:apheresis 306:allograft 226:hepatitis 155:syngeneic 140:autograft 136:autogenic 2124:Lutheran 2029:Dombrock 1814:ISBT 128 1630:Eye bank 1533:Pancreas 1317:ORGANIZE 1278:Advocacy 1085:Pancreas 925:38893108 916:11171011 874:38880643 839:18804939 790:29463251 731:16508504 684:32727659 635:25358862 583:30243765 542:35798344 534:23095610 391:See also 377:lymphoma 271:children 265:such as 237:allergic 219:antibody 107:proteins 2163:Scianna 2049:Gerbich 1952:delayed 1823:Methods 1030:Corneal 781:5819675 654:Surgery 480:2318261 344:ex vivo 339:ex vivo 323:ex vivo 267:cardiac 103:tissues 93:is the 71:D014182 2074:Indian 2019:Cromer 2014:Colton 1739:Plasma 1440:Kidney 1397:People 1249:NOD-Lb 1122:Vagina 1117:Uterus 1112:Thymus 1107:Spleen 1070:Kidney 923:  913:  899:(11). 872:  837:  829:  788:  778:  770:  729:  721:  682:  674:  633:  625:  581:  540:  532:  478:  325:(also 99:organs 2193:Other 2119:Lewis 2109:Knops 2089:KANNO 2034:Duffy 2024:Diego 1947:acute 1862:Tests 1565:Other 1549:Penis 1476:Liver 1404:Heart 1097:Penis 1075:Liver 1055:Heart 1025:Brain 973:Types 538:S2CID 333:, or 327:bench 221:type. 134:, or 117:Greek 112:auto- 79:[ 2173:T-Tn 2158:RHAG 2156:and 2149:Raph 2144:P1PK 2104:Kidd 2094:Kell 2059:GLOB 2044:FORS 2004:CD59 1749:PF24 1699:and 1502:Lung 1297:DKMS 1102:Skin 1080:Lung 1050:Head 1045:Hand 1040:Face 1015:Bone 985:ABOi 921:PMID 870:PMID 835:PMID 827:ISSN 786:PMID 768:ISSN 727:PMID 719:ISSN 680:PMID 672:ISSN 631:PMID 623:ISSN 579:PMID 530:PMID 476:PMID 308:and 299:, a 122:The 65:MeSH 2178:Vel 2168:Sid 2134:MNS 2114:Lan 2084:JMH 2054:GIL 1987:ABO 1035:Eye 911:PMC 901:doi 862:doi 817:doi 776:PMC 758:doi 711:doi 662:doi 658:168 613:doi 569:doi 522:doi 518:256 468:doi 295:In 259:HIV 230:HIV 228:or 217:or 206:). 189:In 142:or 119:). 97:of 2210:: 2188:Yt 2183:Xg 2154:Rh 2139:OK 2129:LW 2098:Xk 2079:JR 2069:Ii 2064:Hh 2039:Er 1840:, 1836:, 919:. 909:. 897:16 895:. 891:. 868:. 858:89 856:. 833:. 825:. 813:48 811:. 807:. 784:. 774:. 766:. 754:16 752:. 748:. 725:. 717:. 707:60 705:. 701:. 678:. 670:. 656:. 652:. 629:. 621:. 609:54 607:. 603:. 591:^ 577:. 565:69 563:. 559:. 536:. 528:. 516:. 497:. 474:. 464:12 462:. 329:, 175:. 146:. 130:, 101:, 2100:) 2096:( 1844:) 1832:( 1689:e 1682:t 1675:v 958:e 951:t 944:v 927:. 903:: 876:. 864:: 841:. 819:: 792:. 760:: 733:. 713:: 686:. 664:: 637:. 615:: 571:: 544:. 524:: 501:. 482:. 470:: 446:. 83:] 41:. 34:. 20:)

Index

Autologous blood donation
Autogenesis
autological

MeSH
D014182
edit on Wikidata
transplantation
organs
tissues
proteins
auto-
Greek
allotransplantation
syngeneic
xenotransplantation
hematopoietic stem cells
nutcracker syndrome
Intraoperative blood salvage
blood banking
blood donation
autotransfusion
intraoperative blood salvage
blood type
antibody
hepatitis
HIV
allergic
HIV
cardiac

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