256:
233:
130:
155:
507:
262:
161:
1540:
1420:"Appropriate function of 11beta-hydroxysteroid dehydrogenase type 1 in the endoplasmic reticulum lumen is dependent on its N-terminal region sharing similar topological determinants with 50-kDa esterase"
1112:"Human liver arylacetamide deacetylase. Molecular cloning of a novel esterase involved in the metabolic activation of arylamine carcinogens with high sequence similarity to hormone-sensitive lipase"
269:
168:
735:
77:
716:
1262:"Targeting proteins to the lumen of endoplasmic reticulum using N-terminal domains of 11beta-hydroxysteroid dehydrogenase and the 50-kDa esterase"
1609:
1297:"Characterization of the rodent genes for arylacetamide deacetylase, a putative microsomal lipase, and evidence for transcriptional regulation"
1015:
arylamine N-acetyltransferase, which catalyzes one of the initial biotransformation pathways for arylamine and heterocyclic amine carcinogens.
1202:
Yamazaki K, Kusano K, Tadano K, Tanaka I (1997). "Radiation hybrid mapping of human arylacetamide deacetylase (AADAC) locus to chromosome 3".
1585:
1092:
1604:
1074:
1385:"Catalog of 680 variations among eight cytochrome p450 ( CYP) genes, nine esterase genes, and two other genes in the Japanese population"
935:
255:
1503:
942:
232:
1154:
1061:
1040:
1057:
1515:
154:
129:
1036:
57:
268:
167:
1173:
Probst MR, Jenö P, Meyer UA (1991). "Purification and characterization of a human liver arylacetamide deacetylase".
261:
160:
1578:
780:
101:
65:
1455:"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)"
761:
1571:
1343:
143:
1231:
Ozols J (1998). "Determination of lumenal orientation of microsomal 50-kDa esterase/N-deacetylase".
1521:
1509:
44:
89:
1332:"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences"
918:
897:
871:
850:
1484:
1441:
1406:
1371:
1318:
1283:
1248:
1219:
1190:
1133:
37:
1555:
1474:
1466:
1431:
1396:
1361:
1351:
1308:
1273:
1240:
1211:
1182:
1123:
348:
279:
223:
178:
506:
85:
323:
107:
1347:
1479:
1454:
1366:
1331:
1128:
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650:
645:
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635:
619:
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548:
1598:
1186:
535:
69:
1551:
341:
120:
93:
1097:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1079:
National Center for
Biotechnology Information, U.S. National Library of Medicine
424:
1401:
1384:
240:
137:
73:
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1261:
680:
484:
362:
307:
294:
206:
193:
81:
1488:
1445:
1436:
1419:
1410:
1375:
1356:
1322:
1313:
1296:
1287:
1215:
1252:
1223:
1194:
1137:
982:
977:
966:
825:
806:
558:
1470:
1012:
792:
747:
1244:
1011:
Microsomal arylacetamide deacetylase competes against the activity of
998:
950:
702:
1539:
1110:
Probst MR, Beer M, Beer D, Jeno P, Meyer UA, Gasser R (Sep 1994).
665:
661:
1547:
1005:
61:
515:
1330:
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
1155:"Entrez Gene: AADAC arylacetamide deacetylase (esterase)"
331:
1559:
1453:
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
1295:
Trickett JI, Patel DD, Knight BL, et al. (2001).
646:
positive regulation of triglyceride catabolic process
496:
1418:
Frick C, Atanasov AG, Arnold P, et al. (2004).
911:
890:
864:
843:
1053:
1051:
1049:
1032:
1030:
1028:
278:
177:
1260:Mziaut H, Korza G, Hand AR, et al. (1999).
1383:Saito S, Iida A, Sekine A, et al. (2003).
16:Protein-coding gene in the species Homo sapiens
1058:GRCm38: Ensembl release 89: ENSMUSG00000027761
1579:
8:
1037:GRCh38: Ensembl release 89: ENSG00000114771
1586:
1572:
676:
531:
319:
218:
115:
1478:
1435:
1400:
1365:
1355:
1312:
1277:
1127:
463:fetal liver hematopoietic progenitor cell
1149:
1147:
620:intracellular membrane-bounded organelle
48:, CES5A1, DAC, arylacetamide deacetylase
1024:
18:
283:
244:
239:
182:
141:
136:
7:
1536:
1534:
554:carboxylic ester hydrolase activity
459:migratory enteric neural crest cell
1558:. You can help Knowledge (XXG) by
908:
887:
861:
840:
816:
797:
771:
752:
726:
707:
501:
419:
357:
336:
14:
1001:that in humans is encoded by the
1538:
505:
267:
260:
254:
231:
166:
159:
153:
128:
605:endoplasmic reticulum membrane
600:integral component of membrane
516:More reference expression data
485:More reference expression data
1:
1610:Human chromosome 3 gene stubs
1175:Biochem. Biophys. Res. Commun
1129:10.1016/S0021-9258(17)31855-0
252:
151:
1336:Proc. Natl. Acad. Sci. U.S.A
1187:10.1016/0006-291X(91)92005-5
636:xenobiotic metabolic process
579:triglyceride lipase activity
1605:Genes on human chromosome 3
1508:human gene location in the
1626:
1533:
1520:human gene details in the
1402:10.1007/s10038-003-0021-7
1093:"Mouse PubMed Reference:"
1075:"Human PubMed Reference:"
995:Arylacetamide deacetylase
981:
976:
972:
965:
949:
936:Chr 3: 151.81 – 151.83 Mb
930:
915:
894:
883:
868:
847:
836:
823:
819:
804:
800:
791:
778:
774:
759:
755:
746:
733:
729:
714:
710:
701:
686:
679:
675:
659:
549:serine hydrolase activity
534:
530:
513:
504:
495:
482:
431:
422:
369:
360:
330:
322:
318:
301:
288:
251:
230:
221:
217:
200:
187:
150:
127:
118:
114:
105:
100:
55:
52:
42:
35:
30:
26:
21:
1279:10.1074/jbc.274.20.14122
943:Chr 3: 59.93 – 59.95 Mb
1437:10.1074/jbc.M313666200
1357:10.1073/pnas.242603899
1314:10.1074/jbc.M101764200
1216:10.1006/geno.1997.4879
610:endoplasmic reticulum
574:deacetylase activity
381:right adrenal cortex
246:Chromosome 3 (mouse)
144:Chromosome 3 (human)
1522:UCSC Genome Browser
1510:UCSC Genome Browser
1348:2002PNAS...9916899M
393:right lobe of liver
389:left adrenal cortex
377:right adrenal gland
1546:This article on a
1471:10.1101/gr.2596504
781:ENSMUSG00000027761
629:Biological process
595:organelle membrane
588:Cellular component
564:hydrolase activity
559:catalytic activity
542:Molecular function
435:left lobe of liver
385:left adrenal gland
1567:
1566:
1342:(26): 16899–903.
1245:10.1021/bi9807916
992:
991:
988:
987:
961:
960:
926:
925:
905:
904:
879:
878:
858:
857:
832:
831:
813:
812:
787:
786:
768:
767:
742:
741:
723:
722:
671:
670:
651:catabolic process
526:
525:
522:
521:
491:
490:
478:
477:
416:
415:
314:
313:
213:
212:
94:AADAC - orthologs
1617:
1588:
1581:
1574:
1542:
1535:
1492:
1482:
1449:
1439:
1414:
1404:
1379:
1369:
1359:
1326:
1316:
1307:(43): 39522–32.
1291:
1281:
1256:
1239:(28): 10336–44.
1227:
1198:
1159:
1158:
1151:
1142:
1141:
1131:
1107:
1101:
1100:
1089:
1083:
1082:
1071:
1065:
1055:
1044:
1034:
974:
973:
945:
938:
921:
909:
900:
888:
884:RefSeq (protein)
874:
862:
853:
841:
817:
798:
772:
753:
727:
708:
677:
532:
518:
509:
502:
487:
427:
425:Top expressed in
420:
405:body of pancreas
365:
363:Top expressed in
358:
337:
320:
310:
297:
286:
271:
264:
258:
247:
235:
219:
209:
196:
185:
170:
163:
157:
146:
132:
116:
110:
96:
47:
40:
19:
1625:
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1620:
1619:
1618:
1616:
1615:
1614:
1595:
1594:
1593:
1592:
1531:
1528:
1500:
1495:
1465:(10B): 2121–7.
1452:
1430:(30): 31131–8.
1417:
1382:
1329:
1294:
1272:(20): 14122–9.
1259:
1230:
1201:
1172:
1168:
1166:Further reading
1163:
1162:
1153:
1152:
1145:
1122:(34): 21650–6.
1109:
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1104:
1091:
1090:
1086:
1073:
1072:
1068:
1056:
1047:
1035:
1026:
1021:
983:View/Edit Mouse
978:View/Edit Human
941:
934:
931:Location (UCSC)
917:
896:
870:
849:
762:ENSG00000114771
655:
624:
583:
569:lipase activity
514:
483:
474:
469:
465:
461:
457:
453:
449:
445:
443:proximal tubule
441:
437:
423:
412:
407:
403:
401:mucosa of ileum
399:
395:
391:
387:
383:
379:
375:
361:
305:
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284:
274:
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272:
265:
245:
222:Gene location (
204:
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173:
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164:
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119:Gene location (
106:
56:
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36:
17:
12:
11:
5:
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1498:External links
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455:precursor cell
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373:jejunal mucosa
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324:RNA expression
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1433:
1429:
1425:
1424:J. Biol. Chem
1421:
1416:
1412:
1408:
1403:
1398:
1395:(5): 249–70.
1394:
1390:
1389:J. Hum. Genet
1386:
1381:
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1373:
1368:
1363:
1358:
1353:
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1337:
1333:
1328:
1324:
1320:
1315:
1310:
1306:
1302:
1301:J. Biol. Chem
1298:
1293:
1289:
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1275:
1271:
1267:
1266:J. Biol. Chem
1263:
1258:
1254:
1250:
1246:
1242:
1238:
1234:
1229:
1225:
1221:
1217:
1213:
1210:(2): 248–50.
1209:
1205:
1200:
1196:
1192:
1188:
1184:
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1176:
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1170:
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1042:
1038:
1033:
1031:
1029:
1025:
1018:
1016:
1014:
1009:
1007:
1004:
1000:
996:
984:
979:
975:
971:
968:
964:
957:
955:
952:
948:
944:
940:
937:
933:
929:
922:
920:
914:
910:
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901:
899:
893:
889:
886:
882:
875:
873:
867:
863:
860:
854:
852:
846:
842:
839:
837:RefSeq (mRNA)
835:
828:
827:
822:
818:
815:
809:
808:
803:
799:
796:
794:
790:
783:
782:
777:
773:
770:
764:
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749:
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738:
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719:
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682:
678:
674:
667:
663:
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560:
557:
555:
552:
550:
547:
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544:
541:
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537:
536:Gene ontology
533:
529:
517:
512:
508:
503:
500:
498:
494:
486:
481:
470:
466:
462:
458:
454:
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109:
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99:
95:
91:
87:
83:
79:
75:
71:
67:
63:
59:
51:
46:
39:
34:
29:
25:
20:
1560:expanding it
1552:chromosome 3
1545:
1530:
1527:
1516:
1504:
1462:
1458:
1427:
1423:
1392:
1388:
1339:
1335:
1304:
1300:
1269:
1265:
1236:
1233:Biochemistry
1232:
1207:
1203:
1181:(1): 453–9.
1178:
1174:
1119:
1115:
1105:
1096:
1087:
1078:
1069:
1010:
1002:
994:
993:
916:
895:
869:
848:
824:
805:
779:
760:
734:
715:
695:
690:
451:human kidney
439:right kidney
347:
340:
205:151,828,488
192:151,814,073
53:External IDs
1116:J Biol Chem
467:gallbladder
409:gallbladder
306:59,947,581
293:59,933,138
31:Identifiers
1599:Categories
1459:Genome Res
1064:, May 2017
1043:, May 2017
1019:References
641:metabolism
351:(ortholog)
285:3|3 D
74:HomoloGene
1550:on human
1013:cytosolic
919:NP_075872
898:NP_001077
872:NM_023383
851:NM_001086
681:Orthologs
102:EC number
82:GeneCards
1489:15489334
1446:15152005
1411:12721789
1376:12477932
1323:11481320
1288:10318829
1204:Genomics
1060:–
1039:–
967:Wikidata
660:Sources:
615:membrane
447:duodenum
397:duodenum
1344:Bibcode
1253:9665742
1224:9299245
1195:2043131
1138:8063807
1062:Ensembl
1041:Ensembl
793:UniProt
748:Ensembl
687:Species
666:QuickGO
471:jejunum
326:pattern
108:3.1.1.3
70:1915008
38:Aliases
1487:
1480:528928
1477:
1444:
1409:
1374:
1367:139241
1364:
1321:
1286:
1251:
1222:
1193:
1136:
999:enzyme
997:is an
953:search
951:PubMed
826:Q99PG0
807:P22760
703:Entrez
497:BioGPS
184:3q25.1
62:600338
1554:is a
1517:AADAC
1505:AADAC
1003:AADAC
736:67758
696:Mouse
691:Human
662:Amigo
349:Mouse
342:Human
289:Start
224:Mouse
188:Start
121:Human
86:AADAC
78:37436
45:AADAC
22:AADAC
1556:stub
1548:gene
1485:PMID
1442:PMID
1407:PMID
1372:PMID
1319:PMID
1284:PMID
1249:PMID
1220:PMID
1191:PMID
1134:PMID
1006:gene
332:Bgee
280:Band
241:Chr.
179:Band
138:Chr.
58:OMIM
1475:PMC
1467:doi
1432:doi
1428:279
1397:doi
1362:PMC
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1274:doi
1270:274
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1183:doi
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