Knowledge (XXG)

ABI gene family member 3

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Miyazaki K, Matsuda S, Ichigotani Y, Takenouchi Y, Hayashi K, Fukuda Y, Nimura Y, Hamaguchi M (Nov 2000). "Isolation and characterization of a novel human gene (NESH) which encodes a putative signaling molecule similar to e3B1 protein".
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Miyazaki K, Matsuda S, Ichigotani Y, et al. (2000). "Isolation and characterization of a novel human gene (NESH) which encodes a putative signaling molecule similar to e3B1 protein".
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Ichigotani Y, Yokozaki S, Fukuda Y, Hamaguchi M, Matsuda S (Apr 2002). "Forced expression of NESH suppresses motility and metastatic dissemination of malignant cells".
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Ichigotani Y, Yokozaki S, Fukuda Y, et al. (2002). "Forced expression of NESH suppresses motility and metastatic dissemination of malignant cells".
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Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network".
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Ichigotani Y, Fujii K, Hamaguchi M, Matsuda S (2002). "In search of a function for the E3B1/Abi2/Argbp1/NESH family (Review)".
1140: 1119: 195: 170: 1136: 1279: 1115: 112: 309: 208: 1682: 302: 201: 781: 120: 762: 1675: 1069: 184: 1590:"NESH (Abi-3) is present in the Abi/WAVE complex but does not promote c-Abl-mediated phosphorylation" 1509: 99: 1285: 931: 906: 876: 851: 1619: 1533: 1403:"Cloning and sequencing of a novel human gene that encodes a putative target protein of Nesh-SH3" 1058: 144: 935: 910: 880: 855: 547: 1611: 1576: 1525: 1488: 1445: 1424: 1389: 1346: 1317: 1234: 1207: 92: 1659: 1601: 1566: 1558: 1517: 1478: 1470: 1414: 1379: 1371: 1338: 1309: 1199: 389: 320: 264: 219: 364: 140: 1513: 1571: 1546: 1065: 1046: 1483: 1458: 1384: 1359: 1342: 1203: 651: 646: 630: 625: 620: 615: 599: 594: 589: 1702: 1655: 576: 1623: 124: 1537: 382: 161: 1606: 1589: 148: 1176:
National Center for Biotechnology Information, U.S. National Library of Medicine
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National Center for Biotechnology Information, U.S. National Library of Medicine
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family. Members of this family encode proteins containing a
1459:"From ORFeome to biology: a functional genomics pipeline" 1360:"DNA cloning using in vitro site-specific recombination" 372: 1663: 1545:
Mehrle A, Rosenfelder H, Schupp I, et al. (2006).
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Matsuda S, Iriyama C, Yokozaki S, et al. (2001).
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may be too technical for most readers to understand
1132: 1130: 1128: 1111: 1109: 1107: 319: 218: 1457:Wiemann S, Arlt D, Huber W, et al. (2004). 16:Protein-coding gene in the species Homo sapiens 1588:Hirao N, Sato S, Gotoh T, et al. (2007). 1137:GRCm38: Ensembl release 89: ENSMUSG00000018381 1683: 1256:"Entrez Gene: ABI3 ABI gene family, member 3" 8: 1116:GRCh38: Ensembl release 89: ENSG00000108798 1690: 1676: 677: 572: 360: 259: 156: 1605: 1570: 1482: 1418: 1383: 1358:Hartley JL, Temple GF, Brasch MA (2001). 62:Learn how and when to remove this message 46:, without removing the technical details. 1250: 1248: 1103: 73: 324: 285: 280: 223: 182: 177: 44:make it understandable to non-experts 7: 1640: 1638: 103:, NESH, SSH3BP3, ABI family member 3 1662:. You can help Knowledge (XXG) by 921: 896: 866: 841: 817: 798: 772: 753: 727: 708: 621:intracellular anatomical structure 542: 460: 398: 377: 14: 1037:This gene encodes a member of an 1022:that in humans is encoded by the 647:peptidyl-tyrosine phosphorylation 1642: 546: 512:lumbar subsegment of spinal cord 308: 301: 295: 272: 207: 200: 194: 169: 23: 1057:. The encoded protein inhibits 1714:Human chromosome 17 gene stubs 557:More reference expression data 526:More reference expression data 1: 1607:10.1016/j.febslet.2006.10.065 1547:"The LIFEdb database in 2006" 1343:10.1016/s0167-4781(00)00158-5 1204:10.1016/s0167-4781(00)00158-5 293: 192: 1709:Genes on human chromosome 17 652:regulation of cell migration 1055:Src-homology 3 (SH3) domain 1730: 1637: 1557:(Database issue): D415–8. 1284:gene details page in the 1064:of tumor cells as well as 1016:new molecule including SH3 1172:"Mouse PubMed Reference:" 1154:"Human PubMed Reference:" 998: 993: 989: 982: 966: 947: 928: 903: 892: 873: 848: 837: 824: 820: 805: 801: 792: 779: 775: 760: 756: 747: 734: 730: 715: 711: 702: 687: 680: 676: 660: 595:identical protein binding 575: 571: 554: 545: 536: 523: 472: 463: 410: 401: 371: 363: 359: 342: 329: 292: 271: 262: 258: 241: 228: 191: 168: 159: 155: 110: 107: 97: 90: 85: 81: 76: 1012:ABI gene family member 3 960:Chr 11: 95.72 – 95.73 Mb 953:Chr 17: 49.21 – 49.22 Mb 484:interventricular septum 450:upper lobe of left lung 1331:Biochim. Biophys. Acta 480:mesenteric lymph nodes 1420:10.1007/s100380170049 1070:p21-activated kinases 1014:(ABI3) also known as 287:Chromosome 11 (mouse) 185:Chromosome 17 (human) 1314:10.3892/ijmm.9.6.591 1278:genome location and 1192:Biochim Biophys Acta 1522:10.1038/nature04209 1514:2005Natur.437.1173R 1286:UCSC Genome Browser 1650:This article on a 1563:10.1093/nar/gkj139 1475:10.1101/gr.2576704 782:ENSMUSG00000018381 640:Biological process 609:Cellular component 600:SH3 domain binding 583:Molecular function 1671: 1670: 1551:Nucleic Acids Res 1376:10.1101/gr.143000 1009: 1008: 1005: 1004: 978: 977: 943: 942: 918: 917: 888: 887: 863: 862: 833: 832: 814: 813: 788: 787: 769: 768: 743: 742: 724: 723: 672: 671: 567: 566: 563: 562: 532: 531: 519: 518: 457: 456: 355: 354: 254: 253: 72: 71: 64: 1721: 1692: 1685: 1678: 1646: 1639: 1627: 1609: 1584: 1574: 1541: 1508:(7062): 1173–8. 1496: 1486: 1469:(10B): 2136–44. 1453: 1432: 1422: 1397: 1387: 1354: 1325: 1302:Int. J. Mol. Med 1260: 1259: 1252: 1243: 1242: 1222: 1216: 1215: 1186: 1180: 1179: 1168: 1162: 1161: 1150: 1144: 1134: 1123: 1113: 1053:rich region and 991: 990: 962: 955: 938: 922: 913: 897: 893:RefSeq (protein) 883: 867: 858: 842: 818: 799: 773: 754: 728: 709: 678: 573: 559: 550: 543: 528: 468: 466:Top expressed in 461: 406: 404:Top expressed in 399: 378: 361: 351: 338: 327: 312: 305: 299: 288: 276: 260: 250: 237: 226: 211: 204: 198: 187: 173: 157: 151: 149:ABI3 - orthologs 102: 95: 74: 67: 60: 56: 53: 47: 27: 26: 19: 1729: 1728: 1724: 1723: 1722: 1720: 1719: 1718: 1699: 1698: 1697: 1696: 1635: 1632: 1630: 1600:(27): 6464–70. 1587: 1544: 1499: 1456: 1435: 1400: 1370:(11): 1788–95. 1357: 1337:(1–2): 237–41. 1328: 1299: 1295: 1293:Further reading 1269: 1264: 1263: 1254: 1253: 1246: 1224: 1223: 1219: 1198:(1–2): 237–41. 1188: 1187: 1183: 1170: 1169: 1165: 1152: 1151: 1147: 1135: 1126: 1114: 1105: 1100: 1078: 1039:adaptor protein 1035: 1000:View/Edit Mouse 995:View/Edit Human 958: 951: 948:Location (UCSC) 934: 930: 909: 905: 879: 875: 854: 850: 763:ENSG00000108798 656: 635: 604: 590:protein binding 555: 524: 515: 510: 506: 502: 498: 494: 490: 486: 482: 478: 464: 453: 448: 444: 440: 436: 432: 428: 424: 420: 416: 402: 346: 333: 325: 315: 314: 313: 306: 286: 263:Gene location ( 245: 232: 224: 214: 213: 212: 205: 183: 160:Gene location ( 111: 98: 91: 68: 57: 51: 48: 40:help improve it 37: 28: 24: 17: 12: 11: 5: 1727: 1725: 1717: 1716: 1711: 1701: 1700: 1695: 1694: 1687: 1680: 1672: 1669: 1668: 1647: 1629: 1628: 1585: 1542: 1497: 1454: 1433: 1398: 1355: 1326: 1296: 1294: 1291: 1290: 1289: 1268: 1267:External links 1265: 1262: 1261: 1244: 1217: 1181: 1163: 1145: 1124: 1102: 1101: 1099: 1096: 1095: 1094: 1089: 1084: 1077: 1074: 1066:cell migration 1034: 1031: 1007: 1006: 1003: 1002: 997: 987: 986: 980: 979: 976: 975: 973: 971: 964: 963: 956: 949: 945: 944: 941: 940: 926: 925: 919: 916: 915: 901: 900: 894: 890: 889: 886: 885: 871: 870: 864: 861: 860: 846: 845: 839: 835: 834: 831: 830: 822: 821: 815: 812: 811: 803: 802: 796: 790: 789: 786: 785: 777: 776: 770: 767: 766: 758: 757: 751: 745: 744: 741: 740: 732: 731: 725: 722: 721: 713: 712: 706: 700: 699: 694: 689: 685: 684: 674: 673: 670: 669: 658: 657: 655: 654: 649: 643: 641: 637: 636: 634: 633: 628: 623: 618: 612: 610: 606: 605: 603: 602: 597: 592: 586: 584: 580: 579: 569: 568: 565: 564: 561: 560: 552: 551: 540: 534: 533: 530: 529: 521: 520: 517: 516: 514: 513: 509: 505: 501: 497: 496:tail of embryo 493: 489: 485: 481: 477: 473: 470: 469: 458: 455: 454: 452: 451: 447: 443: 439: 435: 431: 427: 423: 419: 415: 411: 408: 407: 395: 394: 386: 375: 369: 368: 365:RNA expression 357: 356: 353: 352: 344: 340: 339: 331: 328: 323: 317: 316: 307: 300: 294: 290: 289: 284: 278: 277: 269: 268: 256: 255: 252: 251: 243: 239: 238: 230: 227: 222: 216: 215: 206: 199: 193: 189: 188: 181: 175: 174: 166: 165: 153: 152: 109: 105: 104: 96: 88: 87: 83: 82: 79: 78: 70: 69: 31: 29: 22: 15: 13: 10: 9: 6: 4: 3: 2: 1726: 1715: 1712: 1710: 1707: 1706: 1704: 1693: 1688: 1686: 1681: 1679: 1674: 1673: 1667: 1665: 1661: 1657: 1656:chromosome 17 1653: 1648: 1645: 1641: 1636: 1633: 1625: 1621: 1617: 1613: 1608: 1603: 1599: 1595: 1591: 1586: 1582: 1578: 1573: 1568: 1564: 1560: 1556: 1552: 1548: 1543: 1539: 1535: 1531: 1527: 1523: 1519: 1515: 1511: 1507: 1503: 1498: 1494: 1490: 1485: 1480: 1476: 1472: 1468: 1464: 1460: 1455: 1451: 1447: 1444:(8): 2215–9. 1443: 1439: 1434: 1430: 1426: 1421: 1416: 1412: 1408: 1407:J. Hum. Genet 1404: 1399: 1395: 1391: 1386: 1381: 1377: 1373: 1369: 1365: 1361: 1356: 1352: 1348: 1344: 1340: 1336: 1332: 1327: 1323: 1319: 1315: 1311: 1307: 1303: 1298: 1297: 1292: 1287: 1283: 1282: 1277: 1276: 1271: 1270: 1266: 1257: 1251: 1249: 1245: 1240: 1236: 1233:(8): 2215–9. 1232: 1228: 1221: 1218: 1213: 1209: 1205: 1201: 1197: 1193: 1185: 1182: 1177: 1173: 1167: 1164: 1159: 1155: 1149: 1146: 1142: 1138: 1133: 1131: 1129: 1125: 1121: 1117: 1112: 1110: 1108: 1104: 1097: 1093: 1090: 1088: 1085: 1083: 1080: 1079: 1075: 1073: 1071: 1067: 1063: 1060: 1056: 1052: 1048: 1044: 1040: 1032: 1030: 1028: 1025: 1021: 1017: 1013: 1001: 996: 992: 988: 985: 981: 974: 972: 969: 965: 961: 957: 954: 950: 946: 939: 937: 933: 927: 923: 920: 914: 912: 908: 902: 898: 895: 891: 884: 882: 878: 872: 868: 865: 859: 857: 853: 847: 843: 840: 838:RefSeq (mRNA) 836: 829: 828: 823: 819: 816: 810: 809: 804: 800: 797: 795: 791: 784: 783: 778: 774: 771: 765: 764: 759: 755: 752: 750: 746: 739: 738: 733: 729: 726: 720: 719: 714: 710: 707: 705: 701: 698: 695: 693: 690: 686: 683: 679: 675: 668: 664: 659: 653: 650: 648: 645: 644: 642: 639: 638: 632: 631:lamellipodium 629: 627: 624: 622: 619: 617: 614: 613: 611: 608: 607: 601: 598: 596: 593: 591: 588: 587: 585: 582: 581: 578: 577:Gene ontology 574: 570: 558: 553: 549: 544: 541: 539: 535: 527: 522: 511: 507: 503: 499: 495: 491: 487: 483: 479: 475: 474: 471: 467: 462: 459: 449: 445: 442:apex of heart 441: 438:parotid gland 437: 433: 429: 425: 421: 417: 413: 412: 409: 405: 400: 397: 396: 393: 391: 387: 385: 384: 380: 379: 376: 374: 370: 366: 362: 358: 350: 345: 341: 337: 332: 322: 318: 311: 304: 298: 291: 283: 279: 275: 270: 266: 261: 257: 249: 244: 240: 236: 231: 221: 217: 210: 203: 197: 190: 186: 180: 176: 172: 167: 163: 158: 154: 150: 146: 142: 138: 134: 130: 126: 122: 118: 114: 106: 101: 94: 89: 84: 80: 75: 66: 63: 55: 45: 41: 35: 32:This article 30: 21: 20: 1664:expanding it 1649: 1634: 1631: 1597: 1593: 1554: 1550: 1505: 1501: 1466: 1462: 1441: 1437: 1413:(8): 483–6. 1410: 1406: 1367: 1363: 1334: 1330: 1308:(6): 591–5. 1305: 1301: 1280: 1274: 1230: 1226: 1220: 1195: 1191: 1184: 1175: 1166: 1157: 1148: 1036: 1023: 1018:(Nesh) is a 1015: 1011: 1010: 932:NP_001156936 929: 907:NP_001128658 904: 877:NM_001163464 874: 852:NM_001135186 849: 825: 806: 780: 761: 735: 716: 696: 691: 388: 381: 326:11|11 D 108:External IDs 58: 49: 33: 488:granulocyte 414:granulocyte 347:95,733,302 334:95,720,900 246:49,223,225 233:49,210,411 86:Identifiers 1703:Categories 1463:Genome Res 1438:Cancer Res 1364:Genome Res 1227:Cancer Res 1143:, May 2017 1122:, May 2017 1098:References 1062:metastasis 508:right lung 446:lymph node 392:(ortholog) 129:HomoloGene 52:April 2013 1654:on human 1594:FEBS Lett 1045:homology 936:NP_079935 911:NP_057512 881:NM_025659 856:NM_016428 682:Orthologs 616:cytoplasm 137:GeneCards 1624:20005197 1616:17101133 1581:16381901 1530:16189514 1493:15489336 1450:11956071 1429:11501947 1394:11076863 1351:10978530 1322:12011975 1239:11956071 1212:10978530 1139:– 1118:– 1076:See also 1043:homeobox 1033:Function 984:Wikidata 661:Sources: 626:membrane 504:gastrula 434:appendix 430:testicle 422:monocyte 225:17q21.32 1572:1347501 1538:4427026 1510:Bibcode 1141:Ensembl 1120:Ensembl 1059:ectopic 1051:proline 1020:protein 794:UniProt 749:Ensembl 688:Species 667:QuickGO 367:pattern 125:1913860 93:Aliases 38:Please 1622:  1614:  1579:  1569:  1536:  1528:  1502:Nature 1491:  1484:528930 1481:  1448:  1427:  1392:  1385:310948 1382:  1349:  1320:  1272:Human 1237:  1210:  1092:ABI3BP 1047:domain 970:search 968:PubMed 827:Q8BYZ1 808:Q9P2A4 704:Entrez 538:BioGPS 492:spleen 476:thymus 418:spleen 117:606363 1658:is a 1620:S2CID 1534:S2CID 737:66610 718:51225 697:Mouse 692:Human 663:Amigo 500:blood 426:blood 390:Mouse 383:Human 330:Start 265:Mouse 229:Start 162:Human 1660:stub 1652:gene 1612:PMID 1577:PMID 1526:PMID 1489:PMID 1446:PMID 1425:PMID 1390:PMID 1347:PMID 1335:1493 1318:PMID 1281:ABI3 1275:ABI3 1235:PMID 1208:PMID 1196:1493 1087:ABI2 1082:ABI1 1027:gene 1024:ABI3 373:Bgee 321:Band 282:Chr. 220:Band 179:Chr. 141:ABI3 133:9505 113:OMIM 100:ABI3 77:ABI3 1602:doi 1598:580 1567:PMC 1559:doi 1518:doi 1506:437 1479:PMC 1471:doi 1415:doi 1380:PMC 1372:doi 1339:doi 1310:doi 1200:doi 343:End 242:End 145:OMA 121:MGI 42:to 1705:: 1618:. 1610:. 1596:. 1592:. 1575:. 1565:. 1555:34 1553:. 1549:. 1532:. 1524:. 1516:. 1504:. 1487:. 1477:. 1467:14 1465:. 1461:. 1442:62 1440:. 1423:. 1411:46 1409:. 1405:. 1388:. 1378:. 1368:10 1366:. 1362:. 1345:. 1333:. 1316:. 1304:. 1247:^ 1231:62 1229:. 1206:. 1194:. 1174:. 1156:. 1127:^ 1106:^ 1072:. 1049:, 1029:. 665:/ 349:bp 336:bp 248:bp 235:bp 143:; 139:: 135:; 131:: 127:; 123:: 119:; 115:: 1691:e 1684:t 1677:v 1666:. 1626:. 1604:: 1583:. 1561:: 1540:. 1520:: 1512:: 1495:. 1473:: 1452:. 1431:. 1417:: 1396:. 1374:: 1353:. 1341:: 1324:. 1312:: 1306:9 1288:. 1258:. 1241:. 1214:. 1202:: 1178:. 1160:. 267:) 164:) 147:: 65:) 59:( 54:) 50:( 36:.

Index

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Aliases
ABI3
OMIM
606363
MGI
1913860
HomoloGene
9505
GeneCards
ABI3
OMA
ABI3 - orthologs
Human
Chromosome 17 (human)
Chr.
Chromosome 17 (human)
Chromosome 17 (human)
Genomic location for ABI3
Genomic location for ABI3
Band
bp
bp
Mouse
Chromosome 11 (mouse)
Chr.
Chromosome 11 (mouse)
Genomic location for ABI3

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