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ACTC1

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Actin is a dynamic structure that can adapt two states of flexibility, with the greatest difference between the states occurring as a result of movement within sub-domain 2. Myosin binding increases the flexibility of actin, and cross-linking studies have shown that myosin subfragment-1 binds to
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Matsson H, Eason J, Bookwalter CS, Klar J, Gustavsson P, Sunnegårdh J, Enell H, Jonzon A, Vikkula M, Gutierrez I, Granados-Riveron J, Pope M, Bu'Lock F, Cox J, Robinson TE, Song F, Brook DJ, Marston S, Trybus KM, Dahl N (Jan 2008).
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Zong NC, Li H, Li H, Lam MP, Jimenez RC, Kim CS, Deng N, Kim AK, Choi JH, Zelaya I, Liem D, Meyer D, Odeberg J, Fang C, Lu HJ, Xu T, Weiss J, Duan H, Uhlen M, Yates JR, Apweiler R, Ge J, Hermjakob H, Ping P (Oct 2013).
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Buckingham M, Alonso S, Barton P, Cohen A, Daubas P, Garner I, Robert B, Weydert A (Dec 1986). "Actin and myosin multigene families: their expression during the formation and maturation of striated muscle".
1091:. Alpha cardiac actin is the major protein of the thin filament in cardiac sarcomeres, which are responsible for muscle contraction and generation of force to support the pump function of the heart. 1163:; cardiac/skeletal). The actin monomer has two asymmetric domains; the larger inner domain comprised by sub-domains 3 and 4, and the smaller outer domain by sub-domains 1 and 2. Both the amino and 3113: 3098: 1968:
Klaassen S, Probst S, Oechslin E, Gerull B, Krings G, Schuler P, Greutmann M, Hürlimann D, Yegitbasi M, Pons L, Gramlich M, Drenckhahn JD, Heuser A, Berger F, Jenni R, Thierfelder L (Jun 2008).
1123:. Each actin can bind to four others. The atomic structure of monomeric actin was solved by Kabsch et al., and closely thereafter this same group published the structure of the actin filament. 3083: 2933: 3053: 3038: 3398: 1802:
Olson TM, Doan TP, Kishimoto NY, Whitby FG, Ackerman MJ, Fananapazir L (Sep 2000). "Inherited and de novo mutations in the cardiac actin gene cause hypertrophic cardiomyopathy".
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Cardiac alpha actin is a 42.0 kDa protein composed of 377 amino acids. Cardiac alpha actin is a filamentous protein extending from a complex mesh with cardiac alpha-actinin (
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Monserrat L, Hermida-Prieto M, Fernandez X, Rodríguez I, Dumont C, Cazón L, Cuesta MG, Gonzalez-Juanatey C, Peteiro J, Alvarez N, Penas-Lado M, Castro-Beiras A (Aug 2007).
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are highly conserved proteins; the alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Cardiac (ACTC1) and skeletal (
3008: 3638: 2888: 2882:: CRYSTAL STRUCTURE OF A DICTYOSTELIUM/TETRAHYMENA CHIMERA ACTIN (MUTANT 646: Q228K/T229A/A230Y/A231K/S232E/E360H) IN COMPLEX WITH HUMAN GELSOLIN SEGMENT 1 821: 82: 3563: 3533: 3473: 3458: 3383: 802: 3698: 3683: 3593: 3488: 3353: 2247:"Actin, troponin C, Alzheimer amyloid precursor protein and pro-interleukin 1 beta as substrates of the protease from human immunodeficiency virus" 1880:"Mutation in the alpha-cardiac actin gene associated with apical hypertrophic cardiomyopathy, left ventricular non-compaction, and septal defects" 2852:: CRYSTAL STRUCTURE OF 1:1 COMPLEX BETWEEN GELSOLIN SEGMENT 1 AND A DICTYOSTELIUM/TETRAHYMENA CHIMERA ACTIN (MUTANT 228: Q228K/T229A/A230Y/E360H) 3548: 3443: 3428: 3308: 3293: 3668: 3128: 6129: 3743: 2808: 2075: 1306: 4442: 3653: 3347:: Actin Crystal Dynamics: Structural Implications for F-actin Nucleation, Polymerization and Branching Mediated by the Anti-parallel Dimer 3332:: Actin Crystal Dynamics: Structural Implications for F-actin Nucleation, Polymerization and Branching Mediated by the Anti-parallel Dimer 1288: 3578: 1837:
Arad M, Penas-Lado M, Monserrat L, Maron BJ, Sherrid M, Ho CY, Barr S, Karim A, Olson TM, Kamisago M, Seidman JG, Seidman CE (Nov 2005).
3807: 3518: 2204:"Dinucleotide repeat polymorphism in the human alpha-cardiac actin gene, intron IV (ACTC), detected using the polymerase chain reaction" 1731: 246: 3713: 2828: 2768: 1028: 1021: 3413: 223: 2734: 1718:
Takai E; et al. (Oct 1999). "Mutational analysis of the cardiac actin gene in familial and sporadic dilated cardiomyopathy".
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Orlova A, Egelman EH (Jul 1993). "A conformational change in the actin subunit can change the flexibility of the actin filament".
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Tomasselli AG, Hui JO, Adams L, Chosay J, Lowery D, Greenberg B, Yem A, Deibel MR, Zürcher-Neely H, Heinrikson RL (Aug 1991).
1626:"The covalent maleimidobenzoyl-actin-myosin head complex. Cross-linking of the 50 kDa heavy chain region to actin subdomain-2" 1324:
Kramer PL, Luty JA, Litt M (Jul 1992). "Regional localization of the gene for cardiac muscle actin (ACTC) on chromosome 15q".
5230: 5073: 3800: 145: 120: 3767:: Actin Dimer Cross-linked Between Residues 41 and 374 and proteolytically cleaved by subtilisin between residues 47 and 48. 1271: 2774: 6109: 5663: 1381: 3728: 1250: 3002:: Polylysine Induces an Antiparallel Actin Dimer that Nucleates Filament Assembly: Crystal Structure at 3.5 A Resolution 2957:: THE X-RAY CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN RABBIT SKELETAL MUSCLE ACTIN AND LATRUNCULIN A AT 2.85 A RESOLUTION 2867:: Crystal Structure of Caenorhabditis Elegans Mg-ATP Actin Complexed with Human Gelsolin Segment 1 at 1.75 A resolution. 1219: 62: 4370: 1919:
Morita H, Rehm HL, Menesses A, McDonough B, Roberts AE, Kucherlapati R, Towbin JA, Seidman JG, Seidman CE (May 2008).
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in a small number of Japanese patients. Further studies in patients from South Africa found no association. The E101K
2918: 259: 158: 5841: 2688:"Multiple regions of the human cardiac actin gene are necessary for maturation-based expression in striated muscle" 252: 151: 2801: 2103:
Elzinga M, Maron BJ, Adelstein RS (Jan 1976). "Human heart and platelet actins are products of different genes".
2635:"Nuclear translocation of angiogenin in proliferating endothelial cells is essential to its angiogenic activity" 6074: 2762: 866: 70: 3503: 1452:
Kabsch W, Mannherz HG, Suck D, Pai EF, Holmes KC (Sep 1990). "Atomic structure of the actin:DNase I complex".
3122:: Crystal Structure of D. Discoideum Actin-Gelsolin Segment 1 Complex Crystallized In Presence Of Lithium ATP 6134: 847: 3107:: Crystal Structure of D. Dicsoideum Actin Complexed With Gelsolin Segment 1 and Mg ATP at 1.8 A Resolution 2963: 2721:
Shuster CB, Lin AY, Nayak R, Herman IM (1997). "Beta cap73: a novel beta actin-specific binding protein".
1207: 4493: 3847: 3092:: Crystal Structure Of Dictyostelium Discoideum Actin Complexed With Ca ATP And Human Gelsolin Segment 1 2173:
Dawson SJ, White LA (May 1992). "Treatment of Haemophilus aphrophilus endocarditis with ciprofloxacin".
134: 2557:"alpha-skeletal and alpha-cardiac actin genes are coexpressed in adult human skeletal muscle and heart" 4762: 2794: 2646: 2600:"Reexamination of chromosomal loci of human muscle actin genes by fluorescence in situ hybridization" 2515: 2462: 2366: 2293: 2112: 2059: 2051: 1637: 1512: 1461: 1227: 2942:: STRUCTURE OF BOVINE BETA-ACTIN-PROFILIN COMPLEX WITH ACTIN BOUND ATP PHOSPHATES SOLVENT ACCESSIBLE 6069: 4702: 2780: 49: 4522: 4152: 2038: 1536: 1485: 1191: 94: 1004: 983: 957: 936: 53:, ACTC, ASD5, CMD1R, CMH11, LVNC4, actin, alpha, cardiac muscle 1, actin alpha cardiac muscle 1 5920: 5623: 4284: 3062:: Crystal structure of the chicken actin trimer complexed with human gelsolin segment 1 (GS-1) 2738: 2709: 2674: 2621: 2586: 2543: 2490: 2437: 2394: 2341: 2311: 2268: 2233: 2190: 2161: 2128: 2091: 2071: 2030: 1991: 1950: 1901: 1860: 1819: 1784: 1735: 1700: 1655: 1606: 1571: 1528: 1477: 1434: 1341: 1211: 1183:
gene has a role during development. Experiments in chick embryos found an association between
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actin amino acid residues 48-67 within actin sub-domain 2, which may account for this effect.
42: 5643: 3047:: Crystal structure of the complex of human vitamin D binding protein and rabbit muscle actin 5868: 5575: 5560: 5555: 5550: 5545: 5535: 5456: 5165: 5145: 5115: 5110: 4992: 4347: 4342: 3407:: Structural basis of actin sequestration by thymosin-B4: Implications for arp2/3 activation 2730: 2699: 2664: 2654: 2611: 2576: 2568: 2533: 2523: 2480: 2470: 2427: 2419: 2384: 2374: 2333: 2301: 2258: 2223: 2215: 2182: 2153: 2120: 2081: 2063: 2022: 1981: 1940: 1932: 1891: 1850: 1811: 1774: 1766: 1755:"Cardiac and skeletal actin gene mutations are not a common cause of dilated cardiomyopathy" 1727: 1690: 1645: 1598: 1563: 1520: 1469: 1424: 1416: 1333: 339: 270: 214: 169: 5785: 5780: 5775: 5770: 5525: 5515: 5505: 5500: 5471: 5175: 5170: 4217: 4105: 4095: 4070: 4050: 3954: 3934: 497: 90: 6010: 4624: 4474: 4357: 4177: 314: 1503:
Holmes KC, Popp D, Gebhard W, Kabsch W (Sep 1990). "Atomic model of the actin filament".
3272:: MOLECULAR MODELS OF AVERAGED RIGOR CROSSBRIDGES FROM TOMOGRAMS OF INSECT FLIGHT MUSCLE 3257:: MOLECULAR MODELS OF AVERAGED RIGOR CROSSBRIDGES FROM TOMOGRAMS OF INSECT FLIGHT MUSCLE 3242:: MOLECULAR MODELS OF AVERAGED RIGOR CROSSBRIDGES FROM TOMOGRAMS OF INSECT FLIGHT MUSCLE 3227:: MOLECULAR MODELS OF AVERAGED RIGOR CROSSBRIDGES FROM TOMOGRAMS OF INSECT FLIGHT MUSCLE 3212:: MOLECULAR MODELS OF AVERAGED RIGOR CROSSBRIDGES FROM TOMOGRAMS OF INSECT FLIGHT MUSCLE 3197:: MOLECULAR MODELS OF AVERAGED RIGOR CROSSBRIDGES FROM TOMOGRAMS OF INSECT FLIGHT MUSCLE 3182:: MOLECULAR MODELS OF AVERAGED RIGOR CROSSBRIDGES FROM TOMOGRAMS OF INSECT FLIGHT MUSCLE 3167:: MOLECULAR MODELS OF AVERAGED RIGOR CROSSBRIDGES FROM TOMOGRAMS OF INSECT FLIGHT MUSCLE 3152:: MOLECULAR MODELS OF AVERAGED RIGOR CROSSBRIDGES FROM TOMOGRAMS OF INSECT FLIGHT MUSCLE 3077:: MOLECULAR MODELS OF AVERAGED RIGOR CROSSBRIDGES FROM TOMOGRAMS OF INSECT FLIGHT MUSCLE 3032:: Molecular Models of Averaged Rigor Crossbridges from Tomograms of Insect Flight Muscle 2650: 2519: 2466: 2370: 2297: 2116: 1641: 1516: 1465: 5973: 5836: 4533: 4364: 3873: 3782:: Actin Dimer Cross-linked between Residues 191 and 374 and complexed with Kabiramide C 3632:: Crystal structure of Gelsolin domain 1:ciboulot domain 2 hybrid in complex with actin 2086: 1945: 1920: 1779: 1754: 1429: 1404: 1187: 28: 2704: 2687: 2581: 2556: 2538: 2503: 2485: 2450: 2432: 2407: 2389: 2354: 2263: 2246: 2228: 2203: 2186: 2067: 1986: 1969: 1855: 1838: 736: 731: 726: 721: 716: 711: 706: 701: 696: 691: 686: 681: 676: 671: 666: 661: 645: 640: 635: 630: 625: 620: 615: 610: 605: 600: 595: 590: 585: 580: 575: 570: 554: 549: 544: 539: 6123: 6037: 6032: 4997: 4867: 4816: 4766: 4706: 4628: 4596: 4537: 4323: 3842: 3617:: Crystal structure of Gelsolin domain 1:N-wasp V2 motif hybrid in complex with actin 2987:: CRYSTAL STRUCTURE OF HUMAN VITAMIN D-BINDING PROTEIN IN COMPLEX WITH SKELETAL ACTIN 2669: 2634: 2306: 2281: 1650: 1625: 1567: 1405:"Integration of cardiac proteome biology and medicine by a specialized knowledgebase" 1337: 526: 2013:
Snásel J, Pichová I (1997). "The cleavage of host cell proteins by HIV-1 protease".
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Ueyama H, Inazawa J, Ariyama T, Nishino H, Ochiai Y, Ohkubo I, Miwa T (Mar 1995).
1489: 1420: 1087:. This isoform differs from the alpha actin that is expressed in skeletal muscle, 74: 3287:: Complex Between Rabbit Muscle alpha-Actin: Human Gelsolin Residues Val26-Glu156 2912:: COMPLEX BETWEEN LATRUNCULIN A:RABBIT MUSCLE ALPHA ACTIN:HUMAN GELSOLIN DOMAIN 1 2504:"Chromosomal location of the co-expressed human skeletal and cardiac actin genes" 98: 6027: 5978: 5848: 5738: 5068: 4512: 4467: 4386: 4308: 3856: 2451:"Molecular structure and evolutionary origin of human cardiac muscle actin gene" 2282:"Non-viral cellular substrates for human immunodeficiency virus type 1 protease" 1311:
National Center for Biotechnology Information, U.S. National Library of Medicine
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National Center for Biotechnology Information, U.S. National Library of Medicine
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Proceedings of the National Academy of Sciences of the United States of America
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Proceedings of the National Academy of Sciences of the United States of America
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Proceedings of the National Academy of Sciences of the United States of America
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Proceedings of the National Academy of Sciences of the United States of America
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GeneReviews/NIH/NCBI/UW entry on Familial Hypertrophic Cardiomyopathy Overview
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Egelman EH, Orlova A (Apr 1995). "New insights into actin filament dynamics".
1164: 1152: 231: 128: 78: 5908: 5903: 5898: 5858: 5696: 5691: 5686: 5044: 5024: 4679: 4674: 4654: 4649: 4644: 4634: 4543: 4447: 4381: 2475: 2423: 2337: 2142:"HIV-1 protease cleaves actin during acute infection of human T-lymphocytes" 2124: 1160: 1144: 1140: 1136: 1132: 1108: 1104: 766: 475: 353: 298: 285: 197: 184: 86: 2659: 2528: 2379: 2157: 2095: 1995: 1954: 1905: 1864: 1823: 1815: 1788: 1739: 1732:
10.1002/(sici)1096-8628(19991008)86:4<325::aid-ajmg5>3.0.co;2-u
1704: 1602: 1438: 3017:: CRYSTAL STRUCTURE OF THE COMPLEX OF ACTIN WITH VITAMIN D-BINDING PROTEIN 2742: 2713: 2678: 2625: 2590: 2572: 2547: 2494: 2441: 2406:
Humphries SE, Whittall R, Minty A, Buckingham M, Williamson R (Oct 1981).
2398: 2345: 2315: 2272: 2237: 2194: 2165: 2132: 2034: 1770: 1659: 1610: 1575: 1532: 1481: 1345: 1068: 1063: 6022: 5983: 5915: 5888: 5755: 5743: 5618: 5613: 5054: 5049: 4971: 4405: 4400: 4262: 1936: 1695: 1678: 1052: 911: 892: 1970:"Mutations in sarcomere protein genes in left ventricular noncompaction" 6049: 6003: 5893: 5823: 5792: 5722: 5717: 5681: 5676: 5671: 5638: 5608: 5603: 5598: 5593: 5278: 5210: 5205: 5200: 5195: 5190: 5082: 5019: 4507: 4452: 4393: 4376: 4337: 3823: 2616: 2599: 2026: 1148: 878: 833: 3647:: X-ray Structure of Bistramide A- Actin Complex at 1.35 A resolution. 2140:
Adams LD, Tomasselli AG, Robbins P, Moss B, Heinrikson RL (Feb 1992).
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10.1002/(SICI)1097-0169(1996)35:3<175::AID-CM1>3.0.CO;2-8
1921:"Shared genetic causes of cardiac hypertrophy in children and adults" 1524: 1473: 1156: 1036: 788: 2897:: COMPLEX BETWEEN RABBIT MUSCLE ALPHA-ACTIN: HUMAN GELSOLIN DOMAIN 1 2141: 1374:"Protein Information – Basic Information: Protein COPaKB ID: P68032" 5993: 5765: 5748: 5585: 5580: 5570: 5565: 5530: 5520: 5510: 5495: 5476: 5466: 5461: 5446: 5441: 5436: 5431: 5406: 5391: 5381: 5376: 5361: 5356: 5336: 5331: 5326: 5321: 5316: 5311: 5306: 5301: 5296: 5291: 5286: 5258: 5253: 5220: 5215: 5185: 5180: 5160: 5155: 5135: 5125: 5040: 4918: 4913: 4908: 4903: 4898: 4893: 4888: 4883: 4878: 4873: 4857: 4852: 4847: 4842: 4837: 4832: 4827: 4822: 4797: 4792: 4787: 4782: 4777: 4772: 4752: 4747: 4742: 4737: 4717: 4712: 4422: 4352: 4301: 4298: 4295: 4287: 4276: 4273: 4270: 4255: 4250: 4245: 4240: 4212: 4202: 4187: 4120: 4110: 4090: 4065: 4060: 4045: 4035: 4030: 4025: 4020: 4015: 4010: 3995: 3949: 3944: 3939: 3929: 3924: 3919: 3898: 3893: 3878: 3865: 1128: 1124: 1120: 1116: 1112: 1100: 1088: 2280:
Shoeman RL, Kesselmier C, Mothes E, Höner B, Traub P (Jan 1991).
751: 747: 6094: 6089: 6084: 6044: 6015: 5930: 5807: 5802: 5797: 5701: 5351: 5346: 5341: 5268: 5263: 5130: 5012: 5007: 5002: 4462: 4457: 4415: 4328: 4318: 4313: 4207: 4197: 4192: 4182: 4172: 4167: 4162: 4157: 4080: 4005: 4000: 3990: 3985: 3980: 3975: 3970: 3965: 66: 3796: 2790: 3572:: Structure of Rabbit Actin In Complex With Reidispongiolide C 3542:: Structure of Rabbit Actin In Complex With Reidispongiolide A 3482:: Ternary complex of the WH2 domain of WAVE with Actin-DNAse I 3467:: Ternary complex of the WH2 domain of WASP with Actin-DNAse I 3392:: CRYSTAL STRUCTURE OF CIBOULOT IN COMPLEX WITH SKELETAL ACTIN 2786: 2202:
Watkins C, Bodfish P, Warne D, Nyberg K, Spurr NK (Dec 1991).
3707:: Crystal structure of Monomeric Actin in its ATP-bound state 3692:: Crystal structure of monomeric Actin in the ADP bound state 3602:: Ternary complex of the WH2 domain of mim with actin-dnase I 3497:: Ternary complex of the WH2 Domain of WIP with Actin-DNAse I 1679:"Alpha-cardiac actin mutations produce atrial septal defects" 506: 3362:: Crystal structure of gelsolin domains G1-G3 bound to actin 2058:. International Review of Cytology. Vol. 217. pp.  2758:
Mass spectrometry characterization of human ACTC1 at COPaKB
2408:"There are approximately 20 actin gene in the human genome" 2686:
Dunwoodie SL, Joya JE, Arkell RM, Hardeman EC (Apr 1994).
3557:: Structure of Rabbit Actin In Complex With Sphinxolide B 3452:: Crystal structure of actin in complex with swinholide A 3437:: Bni1p Formin Homology 2 Domain complexed with ATP-actin 3317:: Structure of rabbit actin in complex with jaspisamide A 2502:
Gunning P, Ponte P, Kedes L, Eddy R, Shows T (Mar 1984).
3302:: Structure of rabbit actin in complex with kabiramide C 322: 3677:: SpvB ADP-ribosylated actin: orthorhombic crystal form 3137:: CRYSTAL STRUCTURE OF MONOMERIC ACTIN IN THE ATP STATE 3752:: Actin Dimer Cross-linked Between Residues 41 and 374 1839:"Gene mutations in apical hypertrophic cardiomyopathy" 2355:"Isolation and characterization of human actin genes" 487: 3662:: SpvB ADP-ribosylated actin: hexagonal crystal form 6062: 5961: 5867: 5822: 5731: 5710: 5662: 5485: 5277: 5229: 5081: 5067: 5033: 4980: 4949: 4929: 4808: 4690: 4521: 4503: 4492: 4435: 4228: 3907: 3864: 3855: 3841: 3834: 1360:"Entrez Gene: ACTC1 actin, alpha, cardiac muscle 1" 997: 976: 950: 929: 3587:: THE STRUCTURE OF CRYSTALLINE PROFILIN-BETA-ACTIN 1267: 1265: 1263: 1246: 1244: 1242: 3527:: Crystal Structure of a Cross-linked Actin Dimer 269: 168: 2555:Gunning P, Ponte P, Blau H, Kedes L (Nov 1983). 1131:) alpha actins differ by only four amino acids ( 3722:: Uncomplexed actin cleaved with protease ECP32 2837:: Atomic structure of the actin:DNASE I complex 1671: 1669: 1624:Bertrand R, Derancourt J, Kassab R (May 1994). 16:Protein-coding gene in the species Homo sapiens 1378:Cardiac Organellar Protein Atlas Knowledgebase 1272:GRCm38: Ensembl release 89: ENSMUSG00000068614 3808: 3422:: The structure of Aplyronine A-actin complex 2802: 2449:Hamada H, Petrino MG, Kakunaga T (Oct 1982). 8: 1804:Journal of Molecular and Cellular Cardiology 1251:GRCh38: Ensembl release 89: ENSG00000159251 5078: 4518: 4500: 3861: 3852: 3838: 3815: 3801: 3793: 3377:: Absolute Stereochemistry of Ulapualide A 2809: 2795: 2787: 2353:Engel JN, Gunning PW, Kedes L (Aug 1981). 762: 522: 310: 209: 106: 2703: 2668: 2658: 2615: 2580: 2537: 2527: 2484: 2474: 2431: 2388: 2378: 2305: 2262: 2227: 2085: 1985: 1944: 1895: 1854: 1778: 1694: 1649: 1428: 1167:lie in sub-domain 1 of the outer domain. 677:negative regulation of apoptotic process 2824: 1238: 434:cardiac muscle tissue of left ventricle 2604:The Japanese Journal of Human Genetics 707:positive regulation of gene expression 692:skeletal muscle thin filament assembly 18: 1556:Current Opinion in Structural Biology 372:cardiac muscle tissue of right atrium 274: 235: 230: 173: 132: 127: 7: 2326:American Journal of Medical Genetics 2146:AIDS Research and Human Retroviruses 2050:Bearer EL, Prakash JM, Li Z (2002). 2692:The Journal of Biological Chemistry 2633:Moroianu J, Riordan JF (Mar 1994). 2251:The Journal of Biological Chemistry 1925:The New England Journal of Medicine 1753:Mayosi BM; et al. (Oct 1999). 1111:. Polymerization of globular actin 682:cardiac muscle tissue morphogenesis 3737:: Structure of oxidized beta-actin 2723:Cell Motility and the Cytoskeleton 994: 973: 947: 926: 902: 883: 857: 838: 812: 793: 492: 410: 348: 327: 14: 1987:10.1161/CIRCULATIONAHA.107.746164 1856:10.1161/CIRCULATIONAHA.105.547448 672:actomyosin structure organization 4443:Wiskott–Aldrich syndrome protein 3772: 3757: 3742: 3727: 3712: 3697: 3682: 3667: 3652: 3637: 3622: 3607: 3592: 3577: 3562: 3547: 3532: 3517: 3502: 3487: 3472: 3457: 3442: 3427: 3412: 3397: 3382: 3367: 3352: 3337: 3322: 3307: 3292: 3277: 3262: 3247: 3232: 3217: 3202: 3187: 3172: 3157: 3142: 3127: 3112: 3097: 3082: 3067: 3052: 3037: 3022: 3007: 2992: 2977: 2962: 2947: 2932: 2917: 2902: 2887: 2872: 2857: 2842: 2827: 496: 258: 251: 245: 222: 157: 150: 144: 119: 27: 5664:Microtubule organising proteins 1179:It has been suggested that the 1115:leads to a structural filament 702:actin-mediated cell contraction 2927:: GELSOLIN G4-G6/ACTIN COMPLEX 2561:Molecular and Cellular Biology 1226:gene has been associated with 1222:. Another mutation has in the 1220:left ventricular noncompaction 1119:in the form of a two-stranded 507:More reference expression data 476:More reference expression data 1: 5711:Microtubule severing proteins 2705:10.1016/S0021-9258(17)32703-5 2264:10.1016/S0021-9258(18)98721-1 2187:10.1016/S0163-4453(05)80037-4 2068:10.1016/S0074-7696(02)17014-8 2052:"Actin dynamics in platelets" 1421:10.1161/CIRCRESAHA.113.301151 687:actin filament-based movement 662:actin-myosin filament sliding 243: 142: 6130:Genes on human chromosome 15 4371:actin depolymerizing factors 2307:10.1016/0014-5793(91)80116-K 1651:10.1016/0014-5793(94)00398-x 1591:Journal of Molecular Biology 1568:10.1016/0959-440x(95)80072-7 1338:10.1016/0888-7543(92)90185-U 364:myocardium of left ventricle 5849:Plakoglobin (gamma catenin) 1216:hypertrophic cardiomyopathy 737:actin filament organization 6151: 2779:gene details page in the 1107:towards the center of the 1085:cardiac muscle alpha actin 697:cardiac myofibril assembly 667:cardiac muscle contraction 6105: 2822: 1307:"Mouse PubMed Reference:" 1289:"Human PubMed Reference:" 1214:has been associated with 1067: 1062: 1058: 1051: 1035: 1029:Chr 2: 113.88 – 113.88 Mb 1016: 1001: 980: 969: 954: 933: 922: 909: 905: 890: 886: 877: 864: 860: 845: 841: 832: 819: 815: 800: 796: 787: 772: 765: 761: 745: 525: 521: 504: 495: 486: 473: 422: 413: 360: 351: 321: 313: 309: 292: 279: 242: 221: 212: 208: 191: 178: 141: 118: 109: 105: 60: 57: 47: 40: 35: 26: 21: 6075:Prokaryotic cytoskeleton 2220:10.1093/nar/19.24.6980-a 2175:The Journal of Infection 2056:A Survey of Cell Biology 1897:10.1093/eurheartj/ehm239 1683:Human Molecular Genetics 396:tibialis anterior muscle 3512:: Actin-DNAse I Complex 2476:10.1073/pnas.79.19.5901 2338:10.1002/ajmg.1320250405 2125:10.1126/science.1246600 1190:and a reduction in the 1022:Chr 15: 34.79 – 34.8 Mb 712:muscle filament sliding 446:vastus lateralis muscle 442:interventricular septum 2660:10.1073/pnas.91.5.1677 2529:10.1073/pnas.81.6.1813 2412:Nucleic Acids Research 2380:10.1073/pnas.78.8.4674 2208:Nucleic Acids Research 2158:10.1089/aid.1992.8.291 1884:European Heart Journal 1816:10.1006/jmcc.2000.1204 1603:10.1006/jmbi.1993.1393 1208:dilated cardiomyopathy 450:triceps brachii muscle 426:atrioventricular valve 4695:(hard alpha-keratins) 4526:(soft alpha-keratins) 2573:10.1128/mcb.3.11.1985 2424:10.1093/nar/9.19.4895 1771:10.1136/jmg.36.10.796 1228:atrial septal defects 1198:Clinical significance 646:glutamatergic synapse 621:extracellular exosome 135:Chromosome 15 (human) 6110:cytoskeletal defects 6070:Major sperm proteins 2773:genome location and 1937:10.1056/NEJMoa075463 1409:Circulation Research 1206:have been linked to 717:mesenchyme migration 276:2 E4|2 57.55 cM 237:Chromosome 2 (mouse) 4523:Epithelial keratins 2972:: UNCOMPLEXED ACTIN 2781:UCSC Genome Browser 2651:1994PNAS...91.1677M 2520:1984PNAS...81.1813G 2467:1982PNAS...79.5901H 2371:1981PNAS...78.4674E 2298:1991FEBSL.278..199S 2117:1976Sci...191...94E 1642:1994FEBSL.345..113B 1517:1990Natur.347...44H 1466:1990Natur.347...37K 722:response to ethanol 636:extracellular space 586:blood microparticle 430:endocardial cushion 2617:10.1007/BF01874078 2027:10.1007/BF02818986 1696:10.1093/hmg/ddm302 867:ENSMUSG00000068614 655:Biological process 564:Cellular component 540:nucleotide binding 533:Molecular function 458:extraocular muscle 6117: 6116: 6058: 6057: 5818: 5817: 5063: 5062: 4945: 4944: 4488: 4487: 4431: 4430: 3790: 3789: 2077:978-0-12-364621-7 1212:missense mutation 1202:Polymorphisms in 1078: 1077: 1074: 1073: 1047: 1046: 1012: 1011: 991: 990: 965: 964: 944: 943: 918: 917: 899: 898: 873: 872: 854: 853: 828: 827: 809: 808: 757: 756: 732:apoptotic process 727:heart contraction 517: 516: 513: 512: 482: 481: 469: 468: 407: 406: 305: 304: 204: 203: 99:ACTC1 - orthologs 6142: 5079: 4519: 4501: 3862: 3853: 3839: 3817: 3810: 3803: 3794: 3776: 3761: 3746: 3731: 3716: 3701: 3686: 3671: 3656: 3641: 3626: 3611: 3596: 3581: 3566: 3551: 3536: 3521: 3506: 3491: 3476: 3461: 3446: 3431: 3416: 3401: 3386: 3371: 3356: 3341: 3326: 3311: 3296: 3281: 3266: 3251: 3236: 3221: 3206: 3191: 3176: 3161: 3146: 3131: 3116: 3101: 3086: 3071: 3056: 3041: 3026: 3011: 2996: 2981: 2966: 2951: 2936: 2921: 2906: 2891: 2876: 2861: 2846: 2831: 2811: 2804: 2797: 2788: 2746: 2717: 2707: 2682: 2672: 2662: 2629: 2619: 2594: 2584: 2551: 2541: 2531: 2498: 2488: 2478: 2445: 2435: 2418:(19): 4895–908. 2402: 2392: 2382: 2349: 2319: 2309: 2276: 2266: 2257:(22): 14548–53. 2241: 2231: 2198: 2169: 2136: 2099: 2089: 2046: 2000: 1999: 1989: 1980:(22): 2893–901. 1965: 1959: 1958: 1948: 1931:(18): 1899–908. 1916: 1910: 1909: 1899: 1875: 1869: 1868: 1858: 1834: 1828: 1827: 1799: 1793: 1792: 1782: 1750: 1744: 1743: 1715: 1709: 1708: 1698: 1673: 1664: 1663: 1653: 1621: 1615: 1614: 1586: 1580: 1579: 1551: 1545: 1544: 1525:10.1038/347044a0 1500: 1494: 1493: 1474:10.1038/347037a0 1449: 1443: 1442: 1432: 1399: 1393: 1392: 1390: 1389: 1380:. Archived from 1370: 1364: 1363: 1356: 1350: 1349: 1321: 1315: 1314: 1303: 1297: 1296: 1285: 1279: 1269: 1258: 1248: 1060: 1059: 1031: 1024: 1007: 995: 986: 974: 970:RefSeq (protein) 960: 948: 939: 927: 903: 884: 858: 839: 813: 794: 763: 523: 509: 500: 493: 478: 462:digastric muscle 418: 416:Top expressed in 411: 400:popliteal artery 392:seminal vesicula 356: 354:Top expressed in 349: 328: 311: 301: 288: 277: 262: 255: 249: 238: 226: 210: 200: 187: 176: 161: 154: 148: 137: 123: 107: 101: 52: 45: 31: 19: 6150: 6149: 6145: 6144: 6143: 6141: 6140: 6139: 6120: 6119: 6118: 6113: 6101: 6054: 5957: 5863: 5814: 5727: 5706: 5658: 5481: 5273: 5225: 5071: 5059: 5029: 4976: 4941: 4925: 4809:Ungrouped alpha 4804: 4694: 4686: 4525: 4511: 4505: 4495: 4484: 4427: 4224: 3903: 3845: 3830: 3821: 3791: 3786: 3783: 3777: 3768: 3762: 3753: 3747: 3738: 3732: 3723: 3717: 3708: 3702: 3693: 3687: 3678: 3672: 3663: 3657: 3648: 3642: 3633: 3627: 3618: 3612: 3603: 3597: 3588: 3582: 3573: 3567: 3558: 3552: 3543: 3537: 3528: 3522: 3513: 3507: 3498: 3492: 3483: 3477: 3468: 3462: 3453: 3447: 3438: 3432: 3423: 3417: 3408: 3402: 3393: 3387: 3378: 3372: 3363: 3357: 3348: 3342: 3333: 3327: 3318: 3312: 3303: 3297: 3288: 3282: 3273: 3267: 3258: 3252: 3243: 3237: 3228: 3222: 3213: 3207: 3198: 3192: 3183: 3177: 3168: 3162: 3153: 3147: 3138: 3132: 3123: 3117: 3108: 3102: 3093: 3087: 3078: 3072: 3063: 3057: 3048: 3042: 3033: 3027: 3018: 3012: 3003: 2997: 2988: 2982: 2973: 2967: 2958: 2952: 2943: 2937: 2928: 2922: 2913: 2907: 2898: 2892: 2883: 2877: 2868: 2862: 2853: 2847: 2838: 2832: 2818: 2815: 2754: 2749: 2720: 2698:(16): 12212–9. 2685: 2632: 2597: 2567:(11): 1985–95. 2554: 2501: 2448: 2405: 2352: 2322: 2279: 2244: 2201: 2172: 2139: 2102: 2078: 2049: 2015:Folia Biologica 2012: 2008: 2006:Further reading 2003: 1967: 1966: 1962: 1918: 1917: 1913: 1890:(16): 1953–61. 1877: 1876: 1872: 1849:(18): 2805–11. 1836: 1835: 1831: 1801: 1800: 1796: 1752: 1751: 1747: 1717: 1716: 1712: 1675: 1674: 1667: 1623: 1622: 1618: 1588: 1587: 1583: 1553: 1552: 1548: 1502: 1501: 1497: 1460:(6288): 37–44. 1451: 1450: 1446: 1401: 1400: 1396: 1387: 1385: 1372: 1371: 1367: 1358: 1357: 1353: 1323: 1322: 1318: 1305: 1304: 1300: 1287: 1286: 1282: 1270: 1261: 1249: 1240: 1236: 1200: 1173: 1165:carboxy-termini 1097: 1069:View/Edit Mouse 1064:View/Edit Human 1027: 1020: 1017:Location (UCSC) 1003: 982: 956: 935: 848:ENSG00000159251 741: 650: 559: 550:ATPase activity 505: 474: 465: 460: 456: 452: 448: 444: 440: 436: 432: 428: 414: 403: 398: 394: 390: 386: 382: 378: 374: 370: 368:right ventricle 366: 352: 296: 283: 275: 265: 264: 263: 256: 236: 213:Gene location ( 195: 182: 174: 164: 163: 162: 155: 133: 110:Gene location ( 61: 48: 41: 17: 12: 11: 5: 6148: 6146: 6138: 6137: 6135:Human proteins 6132: 6122: 6121: 6115: 6114: 6106: 6103: 6102: 6100: 6099: 6098: 6097: 6092: 6087: 6082: 6072: 6066: 6064: 6060: 6059: 6056: 6055: 6053: 6052: 6047: 6042: 6041: 6040: 6035: 6025: 6020: 6019: 6018: 6008: 6007: 6006: 6001: 5996: 5991: 5986: 5981: 5976: 5974:Corneodesmosin 5965: 5963: 5959: 5958: 5956: 5955: 5954: 5953: 5948: 5943: 5938: 5933: 5928: 5923: 5913: 5912: 5911: 5906: 5901: 5891: 5886: 5885: 5884: 5873: 5871: 5865: 5864: 5862: 5861: 5856: 5851: 5846: 5845: 5844: 5834: 5828: 5826: 5820: 5819: 5816: 5815: 5813: 5812: 5811: 5810: 5805: 5800: 5790: 5789: 5788: 5783: 5778: 5773: 5768: 5758: 5753: 5752: 5751: 5741: 5735: 5733: 5729: 5728: 5726: 5725: 5720: 5714: 5712: 5708: 5707: 5705: 5704: 5699: 5694: 5689: 5684: 5679: 5674: 5668: 5666: 5660: 5659: 5657: 5656: 5651: 5646: 5641: 5636: 5631: 5626: 5621: 5616: 5611: 5606: 5601: 5596: 5589: 5588: 5583: 5578: 5573: 5568: 5563: 5558: 5553: 5548: 5543: 5538: 5533: 5528: 5523: 5518: 5513: 5508: 5503: 5498: 5491: 5489: 5483: 5482: 5480: 5479: 5474: 5469: 5464: 5459: 5454: 5449: 5444: 5439: 5434: 5429: 5424: 5419: 5414: 5409: 5404: 5399: 5394: 5389: 5384: 5379: 5374: 5369: 5364: 5359: 5354: 5349: 5344: 5339: 5334: 5329: 5324: 5319: 5314: 5309: 5304: 5299: 5294: 5289: 5283: 5281: 5275: 5274: 5272: 5271: 5266: 5261: 5256: 5251: 5246: 5241: 5235: 5233: 5227: 5226: 5224: 5223: 5218: 5213: 5208: 5203: 5198: 5193: 5188: 5183: 5178: 5173: 5168: 5163: 5158: 5153: 5148: 5143: 5138: 5133: 5128: 5123: 5118: 5113: 5108: 5103: 5098: 5093: 5087: 5085: 5076: 5065: 5064: 5061: 5060: 5058: 5057: 5052: 5047: 5041:Nuclear lamins 5037: 5035: 5031: 5030: 5028: 5027: 5022: 5017: 5016: 5015: 5010: 5005: 4995: 4990: 4984: 4982: 4978: 4977: 4975: 4974: 4969: 4964: 4959: 4953: 4951: 4947: 4946: 4943: 4942: 4940: 4939: 4933: 4931: 4927: 4926: 4924: 4923: 4922: 4921: 4916: 4911: 4906: 4901: 4896: 4891: 4886: 4881: 4876: 4863: 4862: 4861: 4860: 4855: 4850: 4845: 4840: 4835: 4830: 4825: 4812: 4810: 4806: 4805: 4803: 4802: 4801: 4800: 4795: 4790: 4785: 4780: 4775: 4758: 4757: 4756: 4755: 4750: 4745: 4740: 4735: 4730: 4725: 4720: 4715: 4698: 4696: 4688: 4687: 4685: 4684: 4683: 4682: 4677: 4672: 4667: 4662: 4657: 4652: 4647: 4642: 4637: 4620: 4619: 4618: 4617: 4607: 4606: 4605: 4593: 4592: 4591: 4586: 4581: 4576: 4571: 4566: 4561: 4556: 4551: 4546: 4529: 4527: 4516: 4498: 4490: 4489: 4486: 4485: 4483: 4482: 4477: 4472: 4471: 4470: 4465: 4460: 4450: 4445: 4439: 4437: 4433: 4432: 4429: 4428: 4426: 4425: 4420: 4419: 4418: 4413: 4403: 4398: 4397: 4396: 4391: 4390: 4389: 4384: 4367: 4365:Arp2/3 complex 4362: 4361: 4360: 4355: 4350: 4345: 4334: 4333: 4332: 4331: 4326: 4321: 4316: 4306: 4305: 4304: 4290: 4279: 4260: 4259: 4258: 4253: 4248: 4243: 4232: 4230: 4226: 4225: 4223: 4222: 4221: 4220: 4215: 4210: 4205: 4200: 4195: 4190: 4185: 4180: 4175: 4170: 4165: 4160: 4150: 4149: 4148: 4143: 4135: 4134: 4133: 4125: 4124: 4123: 4115: 4114: 4113: 4108: 4100: 4099: 4098: 4093: 4085: 4084: 4083: 4075: 4074: 4073: 4068: 4063: 4055: 4054: 4053: 4048: 4040: 4039: 4038: 4033: 4028: 4023: 4018: 4013: 4008: 4003: 3998: 3993: 3988: 3983: 3978: 3973: 3968: 3960: 3959: 3958: 3952: 3947: 3942: 3937: 3932: 3927: 3922: 3913: 3911: 3905: 3904: 3902: 3901: 3896: 3891: 3886: 3881: 3876: 3870: 3868: 3859: 3850: 3843:Microfilaments 3836: 3832: 3831: 3822: 3820: 3819: 3812: 3805: 3797: 3788: 3787: 3785: 3784: 3778: 3771: 3769: 3763: 3756: 3754: 3748: 3741: 3739: 3733: 3726: 3724: 3718: 3711: 3709: 3703: 3696: 3694: 3688: 3681: 3679: 3673: 3666: 3664: 3658: 3651: 3649: 3643: 3636: 3634: 3628: 3621: 3619: 3613: 3606: 3604: 3598: 3591: 3589: 3583: 3576: 3574: 3568: 3561: 3559: 3553: 3546: 3544: 3538: 3531: 3529: 3523: 3516: 3514: 3508: 3501: 3499: 3493: 3486: 3484: 3478: 3471: 3469: 3463: 3456: 3454: 3448: 3441: 3439: 3433: 3426: 3424: 3418: 3411: 3409: 3403: 3396: 3394: 3388: 3381: 3379: 3373: 3366: 3364: 3358: 3351: 3349: 3343: 3336: 3334: 3328: 3321: 3319: 3313: 3306: 3304: 3298: 3291: 3289: 3283: 3276: 3274: 3268: 3261: 3259: 3253: 3246: 3244: 3238: 3231: 3229: 3223: 3216: 3214: 3208: 3201: 3199: 3193: 3186: 3184: 3178: 3171: 3169: 3163: 3156: 3154: 3148: 3141: 3139: 3133: 3126: 3124: 3118: 3111: 3109: 3103: 3096: 3094: 3088: 3081: 3079: 3073: 3066: 3064: 3058: 3051: 3049: 3043: 3036: 3034: 3028: 3021: 3019: 3013: 3006: 3004: 2998: 2991: 2989: 2983: 2976: 2974: 2968: 2961: 2959: 2953: 2946: 2944: 2938: 2931: 2929: 2923: 2916: 2914: 2908: 2901: 2899: 2893: 2886: 2884: 2878: 2871: 2869: 2863: 2856: 2854: 2848: 2841: 2839: 2833: 2826: 2823: 2820: 2819: 2816: 2814: 2813: 2806: 2799: 2791: 2785: 2784: 2765: 2760: 2753: 2752:External links 2750: 2748: 2747: 2718: 2683: 2645:(5): 1677–81. 2630: 2595: 2552: 2499: 2461:(19): 5901–5. 2446: 2403: 2350: 2320: 2292:(2): 199–203. 2277: 2242: 2199: 2170: 2137: 2111:(4222): 94–5. 2100: 2076: 2047: 2009: 2007: 2004: 2002: 2001: 1960: 1911: 1870: 1829: 1810:(9): 1687–94. 1794: 1745: 1720:Am J Med Genet 1710: 1665: 1636:(2–3): 113–9. 1616: 1581: 1546: 1511:(6288): 44–9. 1495: 1444: 1415:(9): 1043–53. 1394: 1365: 1351: 1316: 1298: 1280: 1259: 1237: 1235: 1232: 1199: 1196: 1172: 1169: 1096: 1093: 1076: 1075: 1072: 1071: 1066: 1056: 1055: 1049: 1048: 1045: 1044: 1042: 1040: 1033: 1032: 1025: 1018: 1014: 1013: 1010: 1009: 999: 998: 992: 989: 988: 978: 977: 971: 967: 966: 963: 962: 952: 951: 945: 942: 941: 931: 930: 924: 920: 919: 916: 915: 907: 906: 900: 897: 896: 888: 887: 881: 875: 874: 871: 870: 862: 861: 855: 852: 851: 843: 842: 836: 830: 829: 826: 825: 817: 816: 810: 807: 806: 798: 797: 791: 785: 784: 779: 774: 770: 769: 759: 758: 755: 754: 743: 742: 740: 739: 734: 729: 724: 719: 714: 709: 704: 699: 694: 689: 684: 679: 674: 669: 664: 658: 656: 652: 651: 649: 648: 643: 638: 633: 628: 623: 618: 616:actin filament 613: 608: 603: 601:focal adhesion 598: 593: 588: 583: 578: 573: 567: 565: 561: 560: 558: 557: 552: 547: 545:myosin binding 542: 536: 534: 530: 529: 519: 518: 515: 514: 511: 510: 502: 501: 490: 484: 483: 480: 479: 471: 470: 467: 466: 464: 463: 459: 455: 451: 447: 443: 439: 435: 431: 427: 423: 420: 419: 408: 405: 404: 402: 401: 397: 393: 389: 385: 381: 377: 373: 369: 365: 361: 358: 357: 345: 344: 336: 325: 319: 318: 315:RNA expression 307: 306: 303: 302: 294: 290: 289: 281: 278: 273: 267: 266: 257: 250: 244: 240: 239: 234: 228: 227: 219: 218: 206: 205: 202: 201: 193: 189: 188: 180: 177: 172: 166: 165: 156: 149: 143: 139: 138: 131: 125: 124: 116: 115: 103: 102: 59: 55: 54: 46: 38: 37: 33: 32: 24: 23: 15: 13: 10: 9: 6: 4: 3: 2: 6147: 6136: 6133: 6131: 6128: 6127: 6125: 6112: 6111: 6104: 6096: 6093: 6091: 6088: 6086: 6083: 6081: 6078: 6077: 6076: 6073: 6071: 6068: 6067: 6065: 6061: 6051: 6048: 6046: 6043: 6039: 6036: 6034: 6031: 6030: 6029: 6026: 6024: 6021: 6017: 6014: 6013: 6012: 6009: 6005: 6002: 6000: 5997: 5995: 5992: 5990: 5987: 5985: 5982: 5980: 5977: 5975: 5972: 5971: 5970: 5967: 5966: 5964: 5960: 5952: 5949: 5947: 5944: 5942: 5939: 5937: 5934: 5932: 5929: 5927: 5924: 5922: 5919: 5918: 5917: 5914: 5910: 5907: 5905: 5902: 5900: 5897: 5896: 5895: 5892: 5890: 5887: 5883: 5880: 5879: 5878: 5875: 5874: 5872: 5870: 5866: 5860: 5857: 5855: 5854:Delta catenin 5852: 5850: 5847: 5843: 5840: 5839: 5838: 5835: 5833: 5832:Alpha catenin 5830: 5829: 5827: 5825: 5821: 5809: 5806: 5804: 5801: 5799: 5796: 5795: 5794: 5791: 5787: 5784: 5782: 5779: 5777: 5774: 5772: 5769: 5767: 5764: 5763: 5762: 5759: 5757: 5754: 5750: 5747: 5746: 5745: 5742: 5740: 5737: 5736: 5734: 5730: 5724: 5721: 5719: 5716: 5715: 5713: 5709: 5703: 5700: 5698: 5695: 5693: 5690: 5688: 5685: 5683: 5680: 5678: 5675: 5673: 5670: 5669: 5667: 5665: 5661: 5655: 5652: 5650: 5647: 5645: 5642: 5640: 5637: 5635: 5632: 5630: 5627: 5625: 5622: 5620: 5617: 5615: 5612: 5610: 5607: 5605: 5602: 5600: 5597: 5595: 5592:cytoplasmic: 5591: 5590: 5587: 5584: 5582: 5579: 5577: 5574: 5572: 5569: 5567: 5564: 5562: 5559: 5557: 5554: 5552: 5549: 5547: 5544: 5542: 5539: 5537: 5534: 5532: 5529: 5527: 5524: 5522: 5519: 5517: 5514: 5512: 5509: 5507: 5504: 5502: 5499: 5497: 5493: 5492: 5490: 5488: 5484: 5478: 5475: 5473: 5470: 5468: 5465: 5463: 5460: 5458: 5455: 5453: 5450: 5448: 5445: 5443: 5440: 5438: 5435: 5433: 5430: 5428: 5425: 5423: 5420: 5418: 5415: 5413: 5410: 5408: 5405: 5403: 5400: 5398: 5395: 5393: 5390: 5388: 5385: 5383: 5380: 5378: 5375: 5373: 5370: 5368: 5365: 5363: 5360: 5358: 5355: 5353: 5350: 5348: 5345: 5343: 5340: 5338: 5335: 5333: 5330: 5328: 5325: 5323: 5320: 5318: 5315: 5313: 5310: 5308: 5305: 5303: 5300: 5298: 5295: 5293: 5290: 5288: 5285: 5284: 5282: 5280: 5276: 5270: 5267: 5265: 5262: 5260: 5257: 5255: 5252: 5250: 5247: 5245: 5242: 5240: 5237: 5236: 5234: 5232: 5228: 5222: 5219: 5217: 5214: 5212: 5209: 5207: 5204: 5202: 5199: 5197: 5194: 5192: 5189: 5187: 5184: 5182: 5179: 5177: 5174: 5172: 5169: 5167: 5164: 5162: 5159: 5157: 5154: 5152: 5149: 5147: 5144: 5142: 5139: 5137: 5134: 5132: 5129: 5127: 5124: 5122: 5119: 5117: 5114: 5112: 5109: 5107: 5104: 5102: 5099: 5097: 5094: 5092: 5089: 5088: 5086: 5084: 5080: 5077: 5075: 5070: 5066: 5056: 5053: 5051: 5048: 5046: 5042: 5039: 5038: 5036: 5032: 5026: 5023: 5021: 5018: 5014: 5011: 5009: 5006: 5004: 5001: 5000: 4999: 4998:Neurofilament 4996: 4994: 4991: 4989: 4986: 4985: 4983: 4979: 4973: 4970: 4968: 4965: 4963: 4960: 4958: 4955: 4954: 4952: 4948: 4938: 4935: 4934: 4932: 4928: 4920: 4917: 4915: 4912: 4910: 4907: 4905: 4902: 4900: 4897: 4895: 4892: 4890: 4887: 4885: 4882: 4880: 4877: 4875: 4872: 4871: 4870: 4869: 4868:chromosome 12 4865: 4864: 4859: 4856: 4854: 4851: 4849: 4846: 4844: 4841: 4839: 4836: 4834: 4831: 4829: 4826: 4824: 4821: 4820: 4819: 4818: 4817:chromosome 17 4814: 4813: 4811: 4807: 4799: 4796: 4794: 4791: 4789: 4786: 4784: 4781: 4779: 4776: 4774: 4771: 4770: 4769: 4768: 4767:chromosome 12 4764: 4760: 4759: 4754: 4751: 4749: 4746: 4744: 4741: 4739: 4736: 4734: 4731: 4729: 4726: 4724: 4721: 4719: 4716: 4714: 4711: 4710: 4709: 4708: 4707:chromosome 17 4704: 4700: 4699: 4697: 4693: 4692:Hair keratins 4689: 4681: 4678: 4676: 4673: 4671: 4668: 4666: 4663: 4661: 4658: 4656: 4653: 4651: 4648: 4646: 4643: 4641: 4638: 4636: 4633: 4632: 4631: 4630: 4629:chromosome 12 4626: 4622: 4621: 4616: 4613: 4612: 4611: 4608: 4604: 4601: 4600: 4599: 4598: 4597:chromosome 12 4594: 4590: 4587: 4585: 4582: 4580: 4577: 4575: 4572: 4570: 4567: 4565: 4562: 4560: 4557: 4555: 4552: 4550: 4547: 4545: 4542: 4541: 4540: 4539: 4538:chromosome 17 4535: 4531: 4530: 4528: 4524: 4520: 4517: 4514: 4509: 4502: 4499: 4497: 4494:Intermediate 4491: 4481: 4478: 4476: 4473: 4469: 4466: 4464: 4461: 4459: 4456: 4455: 4454: 4451: 4449: 4446: 4444: 4441: 4440: 4438: 4434: 4424: 4421: 4417: 4414: 4412: 4409: 4408: 4407: 4404: 4402: 4399: 4395: 4392: 4388: 4385: 4383: 4380: 4379: 4378: 4375: 4374: 4373: 4372: 4368: 4366: 4363: 4359: 4356: 4354: 4351: 4349: 4346: 4344: 4341: 4340: 4339: 4336: 4335: 4330: 4327: 4325: 4322: 4320: 4317: 4315: 4312: 4311: 4310: 4307: 4303: 4300: 4297: 4294: 4291: 4289: 4286: 4283: 4280: 4278: 4275: 4272: 4269: 4266: 4265: 4264: 4261: 4257: 4254: 4252: 4249: 4247: 4244: 4242: 4239: 4238: 4237: 4234: 4233: 4231: 4227: 4219: 4216: 4214: 4211: 4209: 4206: 4204: 4201: 4199: 4196: 4194: 4191: 4189: 4186: 4184: 4181: 4179: 4176: 4174: 4171: 4169: 4166: 4164: 4161: 4159: 4156: 4155: 4154: 4151: 4147: 4144: 4142: 4139: 4138: 4136: 4132: 4129: 4128: 4126: 4122: 4119: 4118: 4116: 4112: 4109: 4107: 4104: 4103: 4101: 4097: 4094: 4092: 4089: 4088: 4086: 4082: 4079: 4078: 4076: 4072: 4069: 4067: 4064: 4062: 4059: 4058: 4056: 4052: 4049: 4047: 4044: 4043: 4041: 4037: 4034: 4032: 4029: 4027: 4024: 4022: 4019: 4017: 4014: 4012: 4009: 4007: 4004: 4002: 3999: 3997: 3994: 3992: 3989: 3987: 3984: 3982: 3979: 3977: 3974: 3972: 3969: 3967: 3964: 3963: 3961: 3956: 3953: 3951: 3948: 3946: 3943: 3941: 3938: 3936: 3933: 3931: 3928: 3926: 3923: 3921: 3918: 3917: 3915: 3914: 3912: 3910: 3906: 3900: 3897: 3895: 3892: 3890: 3887: 3885: 3882: 3880: 3877: 3875: 3872: 3871: 3869: 3867: 3863: 3860: 3858: 3854: 3851: 3849: 3844: 3840: 3837: 3833: 3829: 3825: 3818: 3813: 3811: 3806: 3804: 3799: 3798: 3795: 3781: 3775: 3770: 3766: 3760: 3755: 3751: 3745: 3740: 3736: 3730: 3725: 3721: 3715: 3710: 3706: 3700: 3695: 3691: 3685: 3680: 3676: 3670: 3665: 3661: 3655: 3650: 3646: 3640: 3635: 3631: 3625: 3620: 3616: 3610: 3605: 3601: 3595: 3590: 3586: 3580: 3575: 3571: 3565: 3560: 3556: 3550: 3545: 3541: 3535: 3530: 3526: 3520: 3515: 3511: 3505: 3500: 3496: 3490: 3485: 3481: 3475: 3470: 3466: 3460: 3455: 3451: 3445: 3440: 3436: 3430: 3425: 3421: 3415: 3410: 3406: 3400: 3395: 3391: 3385: 3380: 3376: 3370: 3365: 3361: 3355: 3350: 3346: 3340: 3335: 3331: 3325: 3320: 3316: 3310: 3305: 3301: 3295: 3290: 3286: 3280: 3275: 3271: 3265: 3260: 3256: 3250: 3245: 3241: 3235: 3230: 3226: 3220: 3215: 3211: 3205: 3200: 3196: 3190: 3185: 3181: 3175: 3170: 3166: 3160: 3155: 3151: 3145: 3140: 3136: 3130: 3125: 3121: 3115: 3110: 3106: 3100: 3095: 3091: 3085: 3080: 3076: 3070: 3065: 3061: 3055: 3050: 3046: 3040: 3035: 3031: 3025: 3020: 3016: 3010: 3005: 3001: 2995: 2990: 2986: 2980: 2975: 2971: 2965: 2960: 2956: 2950: 2945: 2941: 2935: 2930: 2926: 2920: 2915: 2911: 2905: 2900: 2896: 2890: 2885: 2881: 2875: 2870: 2866: 2860: 2855: 2851: 2845: 2840: 2836: 2830: 2825: 2821: 2812: 2807: 2805: 2800: 2798: 2793: 2792: 2789: 2782: 2778: 2777: 2772: 2771: 2766: 2764: 2761: 2759: 2756: 2755: 2751: 2744: 2740: 2736: 2732: 2729:(3): 175–87. 2728: 2724: 2719: 2715: 2711: 2706: 2701: 2697: 2693: 2689: 2684: 2680: 2676: 2671: 2666: 2661: 2656: 2652: 2648: 2644: 2640: 2636: 2631: 2627: 2623: 2618: 2613: 2609: 2605: 2601: 2596: 2592: 2588: 2583: 2578: 2574: 2570: 2566: 2562: 2558: 2553: 2549: 2545: 2540: 2535: 2530: 2525: 2521: 2517: 2514:(6): 1813–7. 2513: 2509: 2505: 2500: 2496: 2492: 2487: 2482: 2477: 2472: 2468: 2464: 2460: 2456: 2452: 2447: 2443: 2439: 2434: 2429: 2425: 2421: 2417: 2413: 2409: 2404: 2400: 2396: 2391: 2386: 2381: 2376: 2372: 2368: 2365:(8): 4674–8. 2364: 2360: 2356: 2351: 2347: 2343: 2339: 2335: 2332:(4): 623–34. 2331: 2327: 2321: 2317: 2313: 2308: 2303: 2299: 2295: 2291: 2287: 2283: 2278: 2274: 2270: 2265: 2260: 2256: 2252: 2248: 2243: 2239: 2235: 2230: 2225: 2221: 2217: 2213: 2209: 2205: 2200: 2196: 2192: 2188: 2184: 2181:(3): 317–20. 2180: 2176: 2171: 2167: 2163: 2159: 2155: 2151: 2147: 2143: 2138: 2134: 2130: 2126: 2122: 2118: 2114: 2110: 2106: 2101: 2097: 2093: 2088: 2083: 2079: 2073: 2069: 2065: 2061: 2057: 2053: 2048: 2044: 2040: 2036: 2032: 2028: 2024: 2021:(5): 227–30. 2020: 2016: 2011: 2010: 2005: 1997: 1993: 1988: 1983: 1979: 1975: 1971: 1964: 1961: 1956: 1952: 1947: 1942: 1938: 1934: 1930: 1926: 1922: 1915: 1912: 1907: 1903: 1898: 1893: 1889: 1885: 1881: 1874: 1871: 1866: 1862: 1857: 1852: 1848: 1844: 1840: 1833: 1830: 1825: 1821: 1817: 1813: 1809: 1805: 1798: 1795: 1790: 1786: 1781: 1776: 1772: 1768: 1765:(10): 796–7. 1764: 1760: 1756: 1749: 1746: 1741: 1737: 1733: 1729: 1725: 1721: 1714: 1711: 1706: 1702: 1697: 1692: 1689:(2): 256–65. 1688: 1684: 1680: 1672: 1670: 1666: 1661: 1657: 1652: 1647: 1643: 1639: 1635: 1631: 1627: 1620: 1617: 1612: 1608: 1604: 1600: 1597:(2): 334–41. 1596: 1592: 1585: 1582: 1577: 1573: 1569: 1565: 1562:(2): 172–80. 1561: 1557: 1550: 1547: 1542: 1538: 1534: 1530: 1526: 1522: 1518: 1514: 1510: 1506: 1499: 1496: 1491: 1487: 1483: 1479: 1475: 1471: 1467: 1463: 1459: 1455: 1448: 1445: 1440: 1436: 1431: 1426: 1422: 1418: 1414: 1410: 1406: 1398: 1395: 1384:on 2015-09-24 1383: 1379: 1375: 1369: 1366: 1361: 1355: 1352: 1347: 1343: 1339: 1335: 1331: 1327: 1320: 1317: 1312: 1308: 1302: 1299: 1294: 1290: 1284: 1281: 1277: 1273: 1268: 1266: 1264: 1260: 1256: 1252: 1247: 1245: 1243: 1239: 1233: 1231: 1229: 1225: 1221: 1217: 1213: 1209: 1205: 1197: 1195: 1193: 1189: 1186: 1182: 1177: 1170: 1168: 1166: 1162: 1158: 1154: 1150: 1146: 1142: 1138: 1134: 1130: 1126: 1122: 1118: 1114: 1110: 1106: 1102: 1094: 1092: 1090: 1086: 1082: 1070: 1065: 1061: 1057: 1054: 1050: 1043: 1041: 1038: 1034: 1030: 1026: 1023: 1019: 1015: 1008: 1006: 1000: 996: 993: 987: 985: 979: 975: 972: 968: 961: 959: 953: 949: 946: 940: 938: 932: 928: 925: 923:RefSeq (mRNA) 921: 914: 913: 908: 904: 901: 895: 894: 889: 885: 882: 880: 876: 869: 868: 863: 859: 856: 850: 849: 844: 840: 837: 835: 831: 824: 823: 818: 814: 811: 805: 804: 799: 795: 792: 790: 786: 783: 780: 778: 775: 771: 768: 764: 760: 753: 749: 744: 738: 735: 733: 730: 728: 725: 723: 720: 718: 715: 713: 710: 708: 705: 703: 700: 698: 695: 693: 690: 688: 685: 683: 680: 678: 675: 673: 670: 668: 665: 663: 660: 659: 657: 654: 653: 647: 644: 642: 639: 637: 634: 632: 631:lamellipodium 629: 627: 624: 622: 619: 617: 614: 612: 609: 607: 604: 602: 599: 597: 594: 592: 589: 587: 584: 582: 579: 577: 574: 572: 569: 568: 566: 563: 562: 556: 553: 551: 548: 546: 543: 541: 538: 537: 535: 532: 531: 528: 527:Gene ontology 524: 520: 508: 503: 499: 494: 491: 489: 485: 477: 472: 461: 457: 453: 449: 445: 441: 437: 433: 429: 425: 424: 421: 417: 412: 409: 399: 395: 391: 387: 383: 380:apex of heart 379: 376:right auricle 375: 371: 367: 363: 362: 359: 355: 350: 347: 346: 343: 341: 337: 335: 334: 330: 329: 326: 324: 320: 316: 312: 308: 300: 295: 291: 287: 282: 272: 268: 261: 254: 248: 241: 233: 229: 225: 220: 216: 211: 207: 199: 194: 190: 186: 181: 171: 167: 160: 153: 147: 140: 136: 130: 126: 122: 117: 113: 108: 104: 100: 96: 92: 88: 84: 80: 76: 72: 68: 64: 56: 51: 44: 39: 34: 30: 25: 20: 6107: 5882:Dystroglycan 5837:Beta catenin 5069:Microtubules 4937:Beta-keratin 4866: 4815: 4761: 4701: 4623: 4609: 4595: 4532: 4369: 4236:Tropomodulin 3888: 3828:cytoskeleton 3779: 3764: 3749: 3734: 3719: 3704: 3689: 3674: 3659: 3644: 3629: 3614: 3599: 3584: 3569: 3554: 3539: 3524: 3509: 3494: 3479: 3464: 3449: 3434: 3419: 3404: 3389: 3374: 3359: 3344: 3329: 3314: 3299: 3284: 3269: 3254: 3239: 3224: 3209: 3194: 3179: 3164: 3149: 3134: 3119: 3104: 3089: 3074: 3059: 3044: 3029: 3014: 2999: 2984: 2969: 2954: 2939: 2924: 2909: 2894: 2879: 2864: 2849: 2834: 2775: 2769: 2726: 2722: 2695: 2691: 2642: 2638: 2610:(1): 145–8. 2607: 2603: 2564: 2560: 2511: 2507: 2458: 2454: 2415: 2411: 2362: 2358: 2329: 2325: 2289: 2286:FEBS Letters 2285: 2254: 2250: 2214:(24): 6980. 2211: 2207: 2178: 2174: 2152:(2): 291–5. 2149: 2145: 2108: 2104: 2055: 2018: 2014: 1977: 1973: 1963: 1928: 1924: 1914: 1887: 1883: 1873: 1846: 1842: 1832: 1807: 1803: 1797: 1762: 1758: 1748: 1726:(4): 325–7. 1723: 1719: 1713: 1686: 1682: 1633: 1630:FEBS Letters 1629: 1619: 1594: 1590: 1584: 1559: 1555: 1549: 1508: 1504: 1498: 1457: 1453: 1447: 1412: 1408: 1397: 1386:. Retrieved 1382:the original 1377: 1368: 1354: 1332:(3): 904–5. 1329: 1325: 1319: 1310: 1301: 1292: 1283: 1223: 1203: 1201: 1192:atrial septa 1184: 1180: 1178: 1174: 1098: 1084: 1080: 1079: 1002: 981: 955: 934: 910: 891: 865: 846: 820: 801: 781: 776: 626:cytoskeleton 338: 331: 297:113,884,029 284:113,877,763 58:External IDs 6028:Plakophilin 5979:Desmoplakin 5739:Tau protein 4513:Cytokeratin 4309:Tropomyosin 3857:Myofilament 2817:PDB gallery 1974:Circulation 1843:Circulation 1759:J Med Genet 555:ATP binding 454:human fetus 196:34,795,549 183:34,790,230 36:Identifiers 6124:Categories 6108:See also: 6080:Crescentin 5999:Periplakin 5989:Envoplakin 5877:Dystrophin 5494:axonemal: 4988:Internexin 4967:Peripherin 1388:2015-03-15 1278:, May 2017 1257:, May 2017 1234:References 606:filopodium 342:(ortholog) 79:HomoloGene 5697:Centrin 3 5692:Centrin 2 5687:Centrin 1 5025:Syncoilin 4930:Not alpha 4496:filaments 4448:Fibrillin 1188:knockdown 1117:(F-actin) 1113:(G-actin) 1109:sarcomere 1095:Structure 1005:NP_033738 984:NP_005150 958:NM_009608 937:NM_005159 767:Orthologs 611:sarcomere 576:cell body 571:cytoplasm 384:vena cava 87:GeneCards 6063:Nonhuman 6023:Vinculin 5984:Dystonin 5916:Spectrin 5889:Utrophin 5869:Membrane 5824:Catenins 5756:Stathmin 5744:Dynactin 5624:DYNC2LI1 5619:DYNC1LI2 5614:DYNC1LI1 5279:Kinesins 5083:Tubulins 4972:Vimentin 4504:Type 1/2 4406:Profilin 4401:Gelsolin 4263:Troponin 3824:Proteins 2096:12019562 1996:18506004 1955:18403758 1906:17611253 1865:16267253 1824:10966831 1789:10528865 1740:10494087 1705:17947298 1439:23965338 1326:Genomics 1274:– 1253:– 1171:Function 1083:encodes 1053:Wikidata 746:Sources: 591:membrane 6050:PLEKHA7 6004:Plectin 5969:Plakins 5894:Ankyrin 5793:Dynamin 5723:Spastin 5718:Katanin 5682:CAMSAP3 5677:CAMSAP2 5672:CAMSAP1 5644:DYNLRB2 5639:DYNLRB1 5609:DYNC1I2 5604:DYNC1I1 5599:DYNC2H1 5594:DYNC1H1 5487:Dyneins 5211:TUBGCP6 5206:TUBGCP5 5201:TUBGCP4 5196:TUBGCP3 5191:TUBGCP2 5020:Synemin 4763:type II 4625:type II 4508:Keratin 4453:Filamin 4394:Destrin 4377:Cofilin 4338:Actinin 3909:Myosins 3826:of the 2743:8913639 2714:8163527 2679:8127865 2647:Bibcode 2626:7780165 2591:6689196 2548:6584914 2516:Bibcode 2495:6310553 2463:Bibcode 2442:6273789 2399:6272269 2367:Bibcode 2346:3789022 2316:1991513 2294:Bibcode 2273:1907279 2238:1762945 2195:1602151 2166:1540415 2133:1246600 2113:Bibcode 2105:Science 2087:3376087 2043:7617882 2035:8997639 1946:2752150 1780:1734242 1660:8200441 1638:Bibcode 1611:8345515 1576:7648318 1541:4317981 1533:2395461 1513:Bibcode 1482:2395459 1462:Bibcode 1430:4076475 1346:1639426 1276:Ensembl 1255:Ensembl 1105:Z-lines 879:UniProt 834:Ensembl 773:Species 752:QuickGO 641:synapse 581:cytosol 317:pattern 43:Aliases 5951:SPTBN5 5946:SPTBN4 5941:SPTBN2 5936:SPTBN1 5926:SPTAN1 5761:Tektin 5654:DYNLT3 5649:DYNLT1 5634:DYNLL2 5629:DYNLL1 5576:DNALI1 5561:DNAH17 5556:DNAH14 5551:DNAH13 5546:DNAH12 5541:DNAH11 5536:DNAH10 5457:KIF26B 5452:KIF26A 5427:KIF21B 5422:KIF21A 5417:KIF20B 5412:KIF20A 5402:KIF18B 5397:KIF18A 5387:KIF16B 5372:KIF13B 5367:KIF13A 5166:TUBB4Q 5151:TUBB2C 5146:TUBB2B 5141:TUBB2A 5121:TUBA4A 5116:TUBA3E 5111:TUBA3D 5106:TUBA3C 5101:TUBA1C 5096:TUBA1B 5091:TUBA1A 5034:Type 5 4993:Nestin 4981:Type 4 4957:Desmin 4950:Type 3 4703:type I 4534:type I 4480:TRIOBP 4146:MYO18B 4141:MYO18A 4137:XVIII 4131:MYO15A 3866:Actins 2767:Human 2741:  2712:  2677:  2667:  2624:  2589:  2582:370066 2579:  2546:  2539:345011 2536:  2493:  2486:347018 2483:  2440:  2433:327487 2430:  2397:  2390:320222 2387:  2344:  2314:  2271:  2236:  2229:329379 2226:  2193:  2164:  2131:  2094:  2084:  2074:  2060:137–82 2041:  2033:  1994:  1953:  1943:  1904:  1863:  1822:  1787:  1777:  1738:  1703:  1658:  1609:  1574:  1539:  1531:  1505:Nature 1490:925337 1488:  1480:  1454:Nature 1437:  1427:  1344:  1125:Actins 1039:search 1037:PubMed 912:P68033 893:P68032 789:Entrez 596:I band 488:BioGPS 438:atrium 388:glutes 67:102540 6011:Talin 5994:MACF1 5962:Other 5921:SPTA1 5786:TEKT5 5781:TEKT4 5776:TEKT3 5771:TEKT2 5766:TEKT1 5749:DCTN1 5732:Other 5586:DNAL4 5581:DNAL1 5571:DNAI2 5566:DNAI1 5531:DNAH9 5526:DNAH8 5521:DNAH7 5516:DNAH6 5511:DNAH5 5506:DNAH3 5501:DNAH2 5496:DNAH1 5477:KIFC3 5472:KIFC2 5467:KIFC1 5462:KIF27 5447:KIF25 5442:KIF24 5437:KIF23 5432:KIF22 5407:KIF19 5392:KIF17 5382:KIF15 5377:KIF14 5362:KIF12 5357:KIF11 5337:KIF5C 5332:KIF5B 5327:KIF5A 5322:KIF4B 5317:KIF4A 5312:KIF3C 5307:KIF3B 5302:KIF2C 5297:KIF2A 5292:KIF1B 5287:KIF1A 5259:MAP1B 5254:MAP1A 5221:TUBE1 5216:TUBD1 5186:TUBG2 5181:TUBG1 5176:TUBB8 5171:TUBB6 5161:TUBB4 5156:TUBB3 5136:TUBB1 5126:TUBA8 4475:Espin 4436:Other 4423:Titin 4229:Other 4218:MYLL1 4213:MYLK2 4203:MYLIP 4188:MYL6B 4121:MYO10 4111:MYO9B 4106:MYO9A 4096:MYO7B 4091:MYO7A 4071:MYO5C 4066:MYO5B 4061:MYO5A 4051:MYO3B 4046:MYO3A 4036:MYH16 4031:MYH15 4026:MYH14 4021:MYH13 4016:MYH11 4011:MYH10 3996:MYH7B 3955:MYO1H 3950:MYO1G 3945:MYO1F 3940:MYO1E 3935:MYO1D 3930:MYO1C 3925:MYO1B 3920:MYO1A 3835:Human 2776:ACTC1 2770:ACTC1 2670:43226 2039:S2CID 1537:S2CID 1486:S2CID 1224:ACTC1 1204:ACTC1 1185:ACTC1 1181:ACTC1 1129:ACTA1 1121:helix 1103:) at 1101:ACTN2 1089:ACTA1 1081:ACTC1 822:11464 782:Mouse 777:Human 748:Amigo 340:Mouse 333:Human 280:Start 215:Mouse 179:Start 175:15q14 112:Human 91:ACTC1 83:68446 75:87905 50:ACTC1 22:ACTC1 6095:ParM 6090:MreB 6085:FtsZ 6045:ACF7 6038:PKP2 6033:PKP1 6016:TLN1 5931:SPTB 5909:ANK3 5904:ANK2 5899:ANK1 5808:DNM3 5803:DNM2 5798:DNM1 5702:PCM1 5352:KIF9 5347:KIF7 5342:KIF6 5269:MAP4 5264:MAP2 5231:MAPs 5131:TUBB 5074:MAPs 5072:and 5013:NEFH 5008:NEFM 5003:NEFL 4962:GFAP 4610:none 4468:FLNC 4463:FLNB 4458:FLNA 4208:MYLK 4198:MYL9 4193:MYL7 4183:MYL6 4178:MYL5 4173:MYL4 4168:MYL3 4163:MYL2 4158:MYL1 4087:VII 4081:MYO6 4042:III 4006:MYH9 4001:MYH8 3991:MYH7 3986:MYH6 3981:MYH4 3976:MYH3 3971:MYH2 3966:MYH1 3848:ABPs 3846:and 3780:2q36 3765:2q31 3750:2q1n 3735:2oan 3720:2hmp 3705:2hf4 3690:2hf3 3675:2gwk 3660:2gwj 3645:2fxu 3630:2ff6 3615:2ff3 3600:2d1k 3585:2btf 3570:2asp 3555:2aso 3540:2asm 3525:2a5x 3510:2a42 3495:2a41 3480:2a40 3465:2a3z 3450:1yxq 3435:1y64 3420:1wua 3405:1t44 3390:1sqk 3375:1s22 3360:1rgi 3345:1rfq 3330:1rdw 3315:1qz6 3300:1qz5 3285:1p8z 3270:1o1g 3255:1o1f 3240:1o1e 3225:1o1d 3210:1o1c 3195:1o1b 3180:1o1a 3165:1o19 3150:1o18 3135:1nwk 3120:1nmd 3105:1nm1 3090:1nlv 3075:1mvw 3060:1mdu 3045:1ma9 3030:1m8q 3015:1lot 3000:1lcu 2985:1kxp 2970:1j6z 2955:1ijj 2940:1hlu 2925:1h1v 2910:1esv 2895:1eqy 2880:1dej 2865:1d4x 2850:1c0g 2835:1atn 2739:PMID 2710:PMID 2675:PMID 2622:PMID 2587:PMID 2544:PMID 2491:PMID 2438:PMID 2395:PMID 2342:PMID 2312:PMID 2269:PMID 2234:PMID 2191:PMID 2162:PMID 2129:PMID 2092:PMID 2072:ISBN 2031:PMID 1992:PMID 1951:PMID 1902:PMID 1861:PMID 1820:PMID 1785:PMID 1736:PMID 1701:PMID 1656:PMID 1607:PMID 1572:PMID 1529:PMID 1478:PMID 1435:PMID 1342:PMID 1218:and 323:Bgee 271:Band 232:Chr. 170:Band 129:Chr. 63:OMIM 5859:GAN 5842:APC 5249:EB3 5244:EB2 5239:EB1 5045:A/C 4728:33B 4723:33A 4127:XV 4102:IX 4077:VI 3962:II 2731:doi 2700:doi 2696:269 2665:PMC 2655:doi 2612:doi 2577:PMC 2569:doi 2534:PMC 2524:doi 2481:PMC 2471:doi 2428:PMC 2420:doi 2385:PMC 2375:doi 2334:doi 2302:doi 2290:278 2259:doi 2255:266 2224:PMC 2216:doi 2183:doi 2154:doi 2121:doi 2109:191 2082:PMC 2064:doi 2023:doi 1982:doi 1978:117 1941:PMC 1933:doi 1929:358 1892:doi 1851:doi 1847:112 1812:doi 1775:PMC 1767:doi 1728:doi 1691:doi 1646:doi 1634:345 1599:doi 1595:232 1564:doi 1521:doi 1509:347 1470:doi 1458:347 1425:PMC 1417:doi 1413:113 1334:doi 1161:Thr 1159:360 1157:Ser 1153:Met 1151:301 1149:Leu 1145:Asp 1141:Glu 1137:Glu 1133:Asp 293:End 192:End 95:OMA 71:MGI 6126:: 5055:B2 5050:B1 5043:: 4919:80 4914:79 4909:78 4904:77 4899:76 4894:75 4889:74 4884:73 4879:72 4874:71 4858:40 4853:39 4848:28 4843:27 4838:26 4833:25 4828:24 4823:23 4798:86 4793:85 4788:84 4783:83 4778:82 4773:81 4753:38 4748:37 4743:36 4738:35 4733:34 4718:32 4713:31 4670:6C 4665:6B 4660:6A 4640:2A 4615:21 4603:18 4589:20 4584:19 4579:17 4574:16 4569:15 4564:14 4559:13 4554:12 4549:10 4153:LC 4117:X 4057:V 3916:I 3899:G2 3894:G1 3889:C1 3879:A2 3874:A1 2737:. 2727:35 2725:. 2708:. 2694:. 2690:. 2673:. 2663:. 2653:. 2643:91 2641:. 2637:. 2620:. 2608:40 2606:. 2602:. 2585:. 2575:. 2563:. 2559:. 2542:. 2532:. 2522:. 2512:81 2510:. 2506:. 2489:. 2479:. 2469:. 2459:79 2457:. 2453:. 2436:. 2426:. 2414:. 2410:. 2393:. 2383:. 2373:. 2363:78 2361:. 2357:. 2340:. 2330:25 2328:. 2310:. 2300:. 2288:. 2284:. 2267:. 2253:. 2249:. 2232:. 2222:. 2212:19 2210:. 2206:. 2189:. 2179:24 2177:. 2160:. 2148:. 2144:. 2127:. 2119:. 2107:. 2090:. 2080:. 2070:. 2062:. 2054:. 2037:. 2029:. 2019:42 2017:. 1990:. 1976:. 1972:. 1949:. 1939:. 1927:. 1923:. 1900:. 1888:28 1886:. 1882:. 1859:. 1845:. 1841:. 1818:. 1808:32 1806:. 1783:. 1773:. 1763:36 1761:. 1757:. 1734:. 1724:86 1722:. 1699:. 1687:17 1685:. 1681:. 1668:^ 1654:. 1644:. 1632:. 1628:. 1605:. 1593:. 1570:. 1558:. 1535:. 1527:. 1519:. 1507:. 1484:. 1476:. 1468:. 1456:. 1433:. 1423:. 1411:. 1407:. 1376:. 1340:. 1330:13 1328:. 1309:. 1291:. 1262:^ 1241:^ 1230:. 1194:. 1155:, 1147:, 1139:, 803:70 750:/ 299:bp 286:bp 198:bp 185:bp 93:; 89:: 85:; 81:: 77:; 73:: 69:; 65:: 4765:/ 4705:/ 4680:8 4675:7 4655:5 4650:4 4645:3 4635:1 4627:/ 4544:9 4536:/ 4515:) 4510:, 4506:( 4416:2 4411:1 4387:2 4382:1 4358:4 4353:3 4348:2 4343:1 4329:4 4324:3 4319:2 4314:1 4302:3 4299:2 4296:1 4293:I 4288:2 4285:1 4282:C 4277:3 4274:2 4271:1 4268:T 4256:4 4251:3 4246:2 4241:1 3957:) 3884:B 3816:e 3809:t 3802:v 2810:e 2803:t 2796:v 2783:. 2745:. 2733:: 2716:. 2702:: 2681:. 2657:: 2649:: 2628:. 2614:: 2593:. 2571:: 2565:3 2550:. 2526:: 2518:: 2497:. 2473:: 2465:: 2444:. 2422:: 2416:9 2401:. 2377:: 2369:: 2348:. 2336:: 2318:. 2304:: 2296:: 2275:. 2261:: 2240:. 2218:: 2197:. 2185:: 2168:. 2156:: 2150:8 2135:. 2123:: 2115:: 2098:. 2066:: 2045:. 2025:: 1998:. 1984:: 1957:. 1935:: 1908:. 1894:: 1867:. 1853:: 1826:. 1814:: 1791:. 1769:: 1742:. 1730:: 1707:. 1693:: 1662:. 1648:: 1640:: 1613:. 1601:: 1578:. 1566:: 1560:5 1543:. 1523:: 1515:: 1492:. 1472:: 1464:: 1441:. 1419:: 1391:. 1362:. 1348:. 1336:: 1313:. 1295:. 1143:5 1135:4 217:) 114:) 97::

Index


Aliases
ACTC1
OMIM
102540
MGI
87905
HomoloGene
68446
GeneCards
ACTC1
OMA
ACTC1 - orthologs
Human
Chromosome 15 (human)
Chr.
Chromosome 15 (human)
Chromosome 15 (human)
Genomic location for ACTC1
Genomic location for ACTC1
Band
bp
bp
Mouse
Chromosome 2 (mouse)
Chr.
Chromosome 2 (mouse)
Genomic location for ACTC1
Genomic location for ACTC1
Band

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