Knowledge (XXG)

ACTR1A

Source ๐Ÿ“

242: 219: 1095:. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin. ARP1 forms a 37 nm filament-like structure and is the core of the 116: 141: 507: 500: 493: 248: 147: 1099:
complex. It only exists in the dynactin complex in vivo. Highly purified, native Arp1 polymerize rapidly at extremely low concentrations into short filaments in vitro that were similar, but not identical, in length to those in dynactin. With time, these Arp1 filaments appeared to anneal to form
1246:
Lees-Miller JP, Helfman DM, Schroer TA (Oct 1992). "A vertebrate actin-related protein is a component of a multisubunit complex involved in microtubule-based vesicle motility".
255: 154: 2007:
Clark IB, Meyer DI (2000). "Overexpression of normal and mutant Arp1alpha (centractin) differentially affects microtubule organization during mitosis and interphase".
2071:
Fouquet J, Kann M, Souรจs S, Melki R (2000). "ARP1 in Golgi organisation and attachment of manchette microtubules to the nucleus during mammalian spermatogenesis".
790: 771: 77: 48:, ARP1, CTRN1, Arp1A, ARP1 actin-related protein 1 homolog A, centractin alpha, ARP1 actin related protein 1 homolog A, actin related protein 1A 2227: 1228: 1210: 2038:"Human centromeres and neocentromeres show identical distribution patterns of >20 functionally important kinetochore-associated proteins" 241: 1793:
Mao B, Wu W, Li Y, Hoppe D, Stannek P, Glinka A, Niehrs C (2001). "LDL-receptor-related protein 6 is a receptor for Dickkopf proteins".
998: 2193: 1705:"Dynactin-dependent, dynein-driven vesicle transport in the absence of membrane proteins: a role for spectrin and acidic phospholipids" 1005: 218: 1300: 1316:"Ultrastructural analysis of the dynactin complex: an actin-related protein is a component of a filament that resembles F-actin" 1197: 1176: 1746:"Activation of endosomal dynein motors by stepwise assembly of Rab7-RILP-p150Glued, ORP1L, and the receptor betalll spectrin" 1414:"The p150Glued component of the dynactin complex binds to both microtubules and the actin-related protein centractin (Arp-1)" 140: 115: 2205: 1193: 1612:"Centractin (ARP1) associates with spectrin revealing a potential mechanism to link dynactin to intracellular organelles" 1172: 57: 1896:"Beta-centractin: characterization and distribution of a new member of the centractin family of actin-related proteins" 1144: 254: 153: 247: 146: 1087:, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both 835: 65: 2232: 816: 1939:"Localization of motor-related proteins and associated complexes to active, but not inactive, centromeres" 1105: 129: 1858: 1802: 1425: 1255: 506: 2211: 2199: 1128: 981: 930: 44: 1563:"Interactions between the evolutionarily conserved, actin-related protein, Arp11, actin, and Arp1" 2174: 1882: 1826: 1502: 1394: 1279: 1092: 89: 977: 956: 926: 905: 1974:"Specific isoforms of actin-binding proteins on distinct populations of Golgi-derived vesicles" 499: 492: 2166: 2131: 2088: 2059: 2024: 1995: 1960: 1925: 1874: 1849:
Clark SW, Meyer DI (1992). "Centractin is an actin homologue associated with the centrosome".
1818: 1775: 1726: 1685: 1641: 1592: 1543: 1494: 1453: 1386: 1345: 1271: 37: 1744:
Johansson M, Rocha N, Zwart W, Jordens I, Janssen L, Kuijl C, Olkkonen VM, Neefjes J (2007).
1522:"A dynactin subunit with a highly conserved cysteine-rich motif interacts directly with Arp1" 1123:/Arp11. Arp1 has been shown as the domain for dynactin binding to membrane vesicles (such as 2156: 2121: 2113: 2080: 2049: 2016: 1985: 1950: 1915: 1907: 1866: 1810: 1765: 1757: 1716: 1675: 1631: 1623: 1582: 1574: 1533: 1484: 1443: 1433: 1376: 1335: 1327: 1263: 1120: 334: 265: 209: 164: 85: 1473:"Interaction of the p62 subunit of dynactin with Arp1 and the cortical actin cytoskeleton" 1124: 309: 1862: 1806: 1429: 1259: 1770: 1745: 1636: 1611: 1340: 1315: 2126: 2101: 1920: 1895: 1721: 1704: 1587: 1562: 1489: 1472: 1381: 1364: 1301:"Entrez Gene: ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)" 705: 700: 695: 690: 685: 680: 675: 670: 665: 649: 644: 639: 634: 629: 624: 619: 614: 609: 604: 599: 594: 589: 584: 579: 563: 558: 553: 548: 2221: 2161: 2144: 1448: 1413: 535: 2178: 1506: 69: 1886: 1830: 1283: 1088: 327: 106: 1398: 1111:
It has been reported that Arp1 interacts with other dynactin components including
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antigen processing and presentation of exogenous peptide antigen via MHC class II
93: 1703:
Muresan V, Stankewich MC, Steffen W, Morrow JS, Holzbaur EL, Schnapp BJ (2001).
1233:
National Center for Biotechnology Information, U.S. National Library of Medicine
1215:
National Center for Biotechnology Information, U.S. National Library of Medicine
2145:"ARP1 interacts with the 5' flanking region of the coagulation factor VII gene" 1662:
Holleran EA, Ligon LA, Tokito M, Stankewich MC, Morrow JS, Holzbaur EL (2001).
410: 226: 123: 73: 1990: 1973: 2020: 1578: 735: 470: 348: 293: 280: 192: 179: 81: 2170: 2135: 2092: 2063: 2028: 1999: 1822: 1779: 1730: 1689: 1680: 1663: 1627: 1596: 1547: 1538: 1521: 1498: 1438: 1390: 2084: 2054: 2037: 1964: 1955: 1938: 1929: 1911: 1878: 1761: 1645: 1457: 1349: 1331: 1275: 1045: 1040: 1132: 1096: 1084: 1029: 880: 861: 1065: 847: 802: 2117: 1870: 1814: 1267: 1148: 1013: 757: 1116: 1112: 1104:
filaments. As for conventional actin, Arp1 can bind and hydrolyze
1101: 1365:"Self-regulated polymerization of the actin-related protein Arp1" 720: 716: 1100:
longer assemblies but never attained the length of conventional
1072: 515: 61: 1314:
Schafer DA, Gill SR, Cooper JA, Heuser JE, Schroer TA (1994).
1108:, and Arp1 assembly is accompanied by nucleotide hydrolysis. 1972:
Heimann K, Percival JM, Weinberger R, et al. (1999).
1664:"beta III spectrin binds to the Arp1 subunit of dynactin" 691:
endoplasmic reticulum to Golgi vesicle-mediated transport
2102:"DNA Cloning Using In Vitro Site-Specific Recombination" 317: 2036:
Saffery R, Irvine DV, Griffiths B, et al. (2000).
1937:
Faulkner NE, Vig B, Echeverri CJ, et al. (1998).
1610:
Holleran EA, Tokito MK, Karki S, Holzbaur EL (1996).
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regulation of G2/M transition of mitotic cell cycle
1189: 1187: 1185: 1168: 1166: 1164: 1894:Clark SW, Staub O, Clark IB, et al. (1995). 1471:Garces JA, Clark IB, Meyer DI, Vallee RB (1999). 1412:Waterman-Storer CM, Karki S, Holzbaur EL (1995). 264: 163: 1657: 1655: 16:Protein-coding gene in the species Homo sapiens 1194:GRCm38: Ensembl release 89: ENSMUSG00000025228 564:cytoskeletal protein-membrane anchor activity 8: 701:establishment of mitotic spindle orientation 1173:GRCh38: Ensembl release 89: ENSG00000138107 731: 686:ciliary basal body-plasma membrane docking 531: 305: 204: 101: 2160: 2125: 2100:Hartley JL, Temple GF, Brasch MA (2001). 2053: 1989: 1954: 1919: 1769: 1720: 1679: 1635: 1586: 1537: 1488: 1447: 1437: 1380: 1339: 1520:Karki S, Tokito MK, Holzbaur EL (2000). 1295: 1293: 2143:Carew JA, Jackson AA, Bauer KA (2004). 1160: 1083:This gene encodes a 42.6 kD subunit of 18: 666:G2/M transition of mitotic cell cycle 269: 230: 225: 168: 127: 122: 7: 706:nuclear migration along microtubule 967: 946: 916: 895: 871: 852: 826: 807: 781: 762: 487: 405: 343: 322: 14: 1131:) through its association with ฮฒ- 1068:that in humans is encoded by the 2162:10.1046/j.1538-7836.2003.00227.x 505: 498: 491: 253: 246: 240: 217: 152: 145: 139: 114: 1363:Bingham JB, Schroer TA (1999). 1561:Eckley DM, Schroer TA (2003). 590:microtubule associated complex 516:More reference expression data 471:More reference expression data 1: 1722:10.1016/S1097-2765(01)00165-4 1490:10.1016/S0960-9822(00)80122-0 1382:10.1016/S0960-9822(99)80095-5 610:microtubule organizing center 379:muscle layer of sigmoid colon 238: 137: 2228:Genes on human chromosome 10 1418:Proc. Natl. Acad. Sci. U.S.A 2198:human gene location in the 1320:The Journal of Cell Biology 375:stromal cell of endometrium 2249: 2210:human gene details in the 676:vesicle-mediated transport 1229:"Mouse PubMed Reference:" 1211:"Human PubMed Reference:" 1143:ACTR1A has been shown to 1044: 1039: 1035: 1028: 1012: 999:Chr 10: 102.46 โ€“ 102.5 Mb 993: 974: 953: 942: 923: 902: 891: 878: 874: 859: 855: 846: 833: 829: 814: 810: 801: 788: 784: 769: 765: 756: 741: 734: 730: 714: 534: 530: 513: 490: 481: 468: 417: 408: 387:anterior cingulate cortex 355: 346: 316: 308: 304: 287: 274: 237: 216: 207: 203: 186: 173: 136: 113: 104: 100: 55: 52: 42: 35: 30: 26: 21: 1991:10.1074/jbc.274.16.10743 1006:Chr 19: 46.37 โ€“ 46.38 Mb 585:microtubule cytoskeleton 2021:10.1242/jcs.112.20.3507 1579:10.1091/mbc.E03-01-0049 457:internal carotid artery 453:external carotid artery 1681:10.1074/jbc.M104838200 1628:10.1083/jcb.135.6.1815 1539:10.1074/jbc.275.7.4834 1439:10.1073/pnas.92.5.1634 2085:10.1242/jcs.113.5.877 1912:10.1091/mbc.5.12.1301 1762:10.1083/jcb.200606077 1332:10.1083/jcb.126.2.403 620:extracellular exosome 232:Chromosome 19 (mouse) 130:Chromosome 10 (human) 441:facial motor nucleus 363:gastrocnemius muscle 2212:UCSC Genome Browser 2200:UCSC Genome Browser 2055:10.1093/hmg/9.2.175 1956:10.1093/hmg/7.4.671 1863:1992Natur.359..246C 1807:2001Natur.411..321M 1622:(6 Pt 2): 1815โ€“29. 1430:1995PNAS...92.1634W 1260:1992Natur.359..244L 640:COPI-coated vesicle 449:ganglionic eminence 359:ganglionic eminence 2149:J. Thromb. Haemost 1093:cytoplasmic dynein 836:ENSMUSG00000025228 659:Biological process 645:cell cortex region 573:Cellular component 554:nucleotide binding 542:Molecular function 371:right frontal lobe 94:ACTR1A - orthologs 2118:10.1101/gr.143000 1674:(39): 36598โ€“605. 1055: 1054: 1051: 1050: 1024: 1023: 989: 988: 964: 963: 938: 937: 913: 912: 887: 886: 868: 867: 842: 841: 823: 822: 797: 796: 778: 777: 726: 725: 526: 525: 522: 521: 477: 476: 464: 463: 402: 401: 367:prefrontal cortex 300: 299: 199: 198: 2240: 2182: 2164: 2139: 2129: 2096: 2067: 2057: 2032: 2003: 1993: 1984:(16): 10743โ€“50. 1968: 1958: 1933: 1923: 1890: 1871:10.1038/359246a0 1857:(6392): 246โ€“50. 1835: 1834: 1815:10.1038/35077108 1790: 1784: 1783: 1773: 1741: 1735: 1734: 1724: 1700: 1694: 1693: 1683: 1659: 1650: 1649: 1639: 1607: 1601: 1600: 1590: 1558: 1552: 1551: 1541: 1517: 1511: 1510: 1492: 1483:(24): 1497โ€“500. 1468: 1462: 1461: 1451: 1441: 1409: 1403: 1402: 1384: 1360: 1354: 1353: 1343: 1311: 1305: 1304: 1297: 1288: 1287: 1268:10.1038/359244a0 1243: 1237: 1236: 1225: 1219: 1218: 1207: 1201: 1191: 1180: 1170: 1058:Alpha-centractin 1037: 1036: 1008: 1001: 984: 968: 959: 947: 943:RefSeq (protein) 933: 917: 908: 896: 872: 853: 827: 808: 782: 763: 732: 625:dynactin complex 532: 518: 509: 502: 495: 488: 473: 413: 411:Top expressed in 406: 351: 349:Top expressed in 344: 323: 306: 296: 283: 272: 257: 250: 244: 233: 221: 205: 195: 182: 171: 156: 149: 143: 132: 118: 102: 96: 47: 40: 19: 2248: 2247: 2243: 2242: 2241: 2239: 2238: 2237: 2218: 2217: 2190: 2185: 2142: 2112:(11): 1788โ€“95. 2099: 2070: 2042:Hum. Mol. Genet 2035: 2015:(20): 3507โ€“18. 2006: 1971: 1943:Hum. Mol. Genet 1936: 1906:(12): 1301โ€“10. 1900:Mol. Biol. Cell 1893: 1848: 1844: 1842:Further reading 1839: 1838: 1801:(6835): 321โ€“5. 1792: 1791: 1787: 1743: 1742: 1738: 1702: 1701: 1697: 1661: 1660: 1653: 1609: 1608: 1604: 1567:Mol. Biol. Cell 1560: 1559: 1555: 1519: 1518: 1514: 1470: 1469: 1465: 1411: 1410: 1406: 1362: 1361: 1357: 1313: 1312: 1308: 1299: 1298: 1291: 1254:(6392): 244โ€“6. 1245: 1244: 1240: 1227: 1226: 1222: 1209: 1208: 1204: 1192: 1183: 1171: 1162: 1157: 1141: 1081: 1046:View/Edit Mouse 1041:View/Edit Human 1004: 997: 994:Location (UCSC) 980: 976: 955: 929: 925: 904: 817:ENSG00000138107 710: 681:spermatogenesis 654: 568: 559:protein binding 514: 504: 503: 497: 496: 469: 460: 455: 451: 447: 443: 439: 435: 431: 427: 423: 409: 398: 393: 389: 385: 383:cingulate gyrus 381: 377: 373: 369: 365: 361: 347: 291: 278: 270: 260: 259: 258: 251: 231: 208:Gene location ( 190: 177: 169: 159: 158: 157: 150: 128: 105:Gene location ( 56: 43: 36: 17: 12: 11: 5: 2246: 2244: 2236: 2235: 2233:Human proteins 2230: 2220: 2219: 2216: 2215: 2203: 2189: 2188:External links 2186: 2184: 2183: 2140: 2097: 2068: 2033: 2004: 1969: 1934: 1891: 1845: 1843: 1840: 1837: 1836: 1785: 1736: 1695: 1651: 1602: 1573:(7): 2645โ€“54. 1553: 1512: 1463: 1404: 1355: 1326:(2): 403โ€“412. 1306: 1289: 1238: 1220: 1202: 1181: 1159: 1158: 1156: 1153: 1140: 1137: 1080: 1077: 1053: 1052: 1049: 1048: 1043: 1033: 1032: 1026: 1025: 1022: 1021: 1019: 1017: 1010: 1009: 1002: 995: 991: 990: 987: 986: 972: 971: 965: 962: 961: 951: 950: 944: 940: 939: 936: 935: 921: 920: 914: 911: 910: 900: 899: 893: 889: 888: 885: 884: 876: 875: 869: 866: 865: 857: 856: 850: 844: 843: 840: 839: 831: 830: 824: 821: 820: 812: 811: 805: 799: 798: 795: 794: 786: 785: 779: 776: 775: 767: 766: 760: 754: 753: 748: 743: 739: 738: 728: 727: 724: 723: 712: 711: 709: 708: 703: 698: 693: 688: 683: 678: 673: 668: 662: 660: 656: 655: 653: 652: 647: 642: 637: 632: 627: 622: 617: 612: 607: 602: 597: 592: 587: 582: 576: 574: 570: 569: 567: 566: 561: 556: 551: 545: 543: 539: 538: 528: 527: 524: 523: 520: 519: 511: 510: 485: 479: 478: 475: 474: 466: 465: 462: 461: 459: 458: 454: 450: 446: 442: 438: 434: 430: 426: 422: 418: 415: 414: 403: 400: 399: 397: 396: 392: 388: 384: 380: 376: 372: 368: 364: 360: 356: 353: 352: 340: 339: 331: 320: 314: 313: 310:RNA expression 302: 301: 298: 297: 289: 285: 284: 276: 273: 268: 262: 261: 252: 245: 239: 235: 234: 229: 223: 222: 214: 213: 201: 200: 197: 196: 188: 184: 183: 175: 172: 167: 161: 160: 151: 144: 138: 134: 133: 126: 120: 119: 111: 110: 98: 97: 54: 50: 49: 41: 33: 32: 28: 27: 24: 23: 15: 13: 10: 9: 6: 4: 3: 2: 2245: 2234: 2231: 2229: 2226: 2225: 2223: 2213: 2209: 2208: 2204: 2201: 2197: 2196: 2192: 2191: 2187: 2180: 2176: 2172: 2168: 2163: 2158: 2155:(6): 1220โ€“7. 2154: 2150: 2146: 2141: 2137: 2133: 2128: 2123: 2119: 2115: 2111: 2107: 2103: 2098: 2094: 2090: 2086: 2082: 2079:(5): 877โ€“86. 2078: 2074: 2069: 2065: 2061: 2056: 2051: 2048:(2): 175โ€“85. 2047: 2043: 2039: 2034: 2030: 2026: 2022: 2018: 2014: 2010: 2005: 2001: 1997: 1992: 1987: 1983: 1979: 1978:J. Biol. Chem 1975: 1970: 1966: 1962: 1957: 1952: 1948: 1944: 1940: 1935: 1931: 1927: 1922: 1917: 1913: 1909: 1905: 1901: 1897: 1892: 1888: 1884: 1880: 1876: 1872: 1868: 1864: 1860: 1856: 1852: 1847: 1846: 1841: 1832: 1828: 1824: 1820: 1816: 1812: 1808: 1804: 1800: 1796: 1789: 1786: 1781: 1777: 1772: 1767: 1763: 1759: 1756:(4): 459โ€“71. 1755: 1751: 1747: 1740: 1737: 1732: 1728: 1723: 1718: 1715:(1): 173โ€“83. 1714: 1710: 1706: 1699: 1696: 1691: 1687: 1682: 1677: 1673: 1669: 1668:J. Biol. Chem 1665: 1658: 1656: 1652: 1647: 1643: 1638: 1633: 1629: 1625: 1621: 1617: 1613: 1606: 1603: 1598: 1594: 1589: 1584: 1580: 1576: 1572: 1568: 1564: 1557: 1554: 1549: 1545: 1540: 1535: 1532:(7): 4834โ€“9. 1531: 1527: 1526:J. Biol. Chem 1523: 1516: 1513: 1508: 1504: 1500: 1496: 1491: 1486: 1482: 1478: 1474: 1467: 1464: 1459: 1455: 1450: 1445: 1440: 1435: 1431: 1427: 1424:(5): 1634โ€“8. 1423: 1419: 1415: 1408: 1405: 1400: 1396: 1392: 1388: 1383: 1378: 1374: 1370: 1366: 1359: 1356: 1351: 1347: 1342: 1337: 1333: 1329: 1325: 1321: 1317: 1310: 1307: 1302: 1296: 1294: 1290: 1285: 1281: 1277: 1273: 1269: 1265: 1261: 1257: 1253: 1249: 1242: 1239: 1234: 1230: 1224: 1221: 1216: 1212: 1206: 1203: 1199: 1195: 1190: 1188: 1186: 1182: 1178: 1174: 1169: 1167: 1165: 1161: 1154: 1152: 1150: 1146: 1138: 1136: 1134: 1130: 1129:late endosome 1126: 1122: 1118: 1114: 1109: 1107: 1103: 1098: 1094: 1090: 1086: 1078: 1076: 1074: 1071: 1067: 1063: 1059: 1047: 1042: 1038: 1034: 1031: 1027: 1020: 1018: 1015: 1011: 1007: 1003: 1000: 996: 992: 985: 983: 979: 973: 969: 966: 960: 958: 952: 948: 945: 941: 934: 932: 928: 922: 918: 915: 909: 907: 901: 897: 894: 892:RefSeq (mRNA) 890: 883: 882: 877: 873: 870: 864: 863: 858: 854: 851: 849: 845: 838: 837: 832: 828: 825: 819: 818: 813: 809: 806: 804: 800: 793: 792: 787: 783: 780: 774: 773: 768: 764: 761: 759: 755: 752: 749: 747: 744: 740: 737: 733: 729: 722: 718: 713: 707: 704: 702: 699: 697: 694: 692: 689: 687: 684: 682: 679: 677: 674: 672: 669: 667: 664: 663: 661: 658: 657: 651: 648: 646: 643: 641: 638: 636: 633: 631: 628: 626: 623: 621: 618: 616: 613: 611: 608: 606: 603: 601: 600:myelin sheath 598: 596: 593: 591: 588: 586: 583: 581: 578: 577: 575: 572: 571: 565: 562: 560: 557: 555: 552: 550: 547: 546: 544: 541: 540: 537: 536:Gene ontology 533: 529: 517: 512: 508: 501: 494: 489: 486: 484: 480: 472: 467: 456: 452: 448: 444: 440: 436: 432: 428: 424: 420: 419: 416: 412: 407: 404: 394: 391:apex of heart 390: 386: 382: 378: 374: 370: 366: 362: 358: 357: 354: 350: 345: 342: 341: 338: 336: 332: 330: 329: 325: 324: 321: 319: 315: 311: 307: 303: 295: 290: 286: 282: 277: 271:19|19 C3 267: 263: 256: 249: 243: 236: 228: 224: 220: 215: 211: 206: 202: 194: 189: 185: 181: 176: 166: 162: 155: 148: 142: 135: 131: 125: 121: 117: 112: 108: 103: 99: 95: 91: 87: 83: 79: 75: 71: 67: 63: 59: 51: 46: 39: 34: 29: 25: 20: 2206: 2194: 2152: 2148: 2109: 2105: 2076: 2072: 2045: 2041: 2012: 2008: 1981: 1977: 1949:(4): 671โ€“7. 1946: 1942: 1903: 1899: 1854: 1850: 1798: 1794: 1788: 1753: 1750:J. Cell Biol 1749: 1739: 1712: 1708: 1698: 1671: 1667: 1619: 1616:J. Cell Biol 1615: 1605: 1570: 1566: 1556: 1529: 1525: 1515: 1480: 1476: 1466: 1421: 1417: 1407: 1375:(4): 223โ€“6. 1372: 1368: 1358: 1323: 1319: 1309: 1251: 1247: 1241: 1232: 1223: 1214: 1205: 1142: 1139:Interactions 1110: 1089:microtubules 1082: 1069: 1061: 1057: 1056: 982:NP_001351999 975: 954: 931:NM_001365070 924: 903: 879: 860: 834: 815: 789: 770: 750: 745: 615:cytoskeleton 433:otic placode 429:spermatocyte 421:otic vesicle 333: 326: 191:102,502,712 178:102,461,881 53:External IDs 2073:J. Cell Sci 2009:J. Cell Sci 1060:(yeast) or 650:cell cortex 549:ATP binding 292:46,384,187 279:46,365,250 31:Identifiers 2222:Categories 2106:Genome Res 1477:Curr. Biol 1369:Curr. Biol 1200:, May 2017 1179:, May 2017 1155:References 605:centrosome 395:C1 segment 337:(ortholog) 74:HomoloGene 1709:Mol. Cell 1119:/p62 and 978:NP_058556 957:NP_005727 927:NM_016860 906:NM_005736 736:Orthologs 635:centriole 630:manchette 595:cytoplasm 437:spermatid 82:GeneCards 2179:13442414 2171:12871323 2136:11076863 2093:10671377 2064:10607828 2029:10504299 2000:10196146 1823:11357136 1780:17283181 1731:11172722 1690:11461920 1597:12857853 1548:10671518 1507:10924633 1499:10607597 1391:10074429 1196:– 1175:– 1145:interact 1133:spectrin 1097:dynactin 1085:dynactin 1079:Function 1030:Wikidata 715:Sources: 170:10q24.32 1965:9499420 1930:7696711 1887:4352549 1879:1356230 1859:Bibcode 1831:4323027 1803:Bibcode 1771:2063981 1646:8991093 1637:2133946 1458:7878030 1426:Bibcode 1350:7518465 1341:2200042 1284:4239305 1276:1528266 1256:Bibcode 1198:Ensembl 1177:Ensembl 1115:/p150, 1066:protein 848:UniProt 803:Ensembl 742:Species 721:QuickGO 580:cytosol 425:saccule 312:pattern 70:1858964 38:Aliases 2207:ACTR1A 2195:ACTR1A 2177:  2169:  2134:  2127:310948 2124:  2091:  2062:  2027:  1998:  1963:  1928:  1921:301159 1918:  1885:  1877:  1851:Nature 1829:  1821:  1795:Nature 1778:  1768:  1729:  1688:  1644:  1634:  1595:  1588:165665 1585:  1546:  1505:  1497:  1456:  1446:  1399:208851 1397:  1389:  1348:  1338:  1282:  1274:  1248:Nature 1149:SPTBN2 1121:Actr10 1070:ACTR1A 1016:search 1014:PubMed 881:P61164 862:P61163 758:Entrez 483:BioGPS 86:ACTR1A 62:605143 45:ACTR1A 22:ACTR1A 2175:S2CID 1883:S2CID 1827:S2CID 1503:S2CID 1449:42574 1395:S2CID 1280:S2CID 1147:with 1125:Golgi 1117:DCTN4 1113:DCTN1 1102:actin 1064:is a 791:54130 772:10121 751:Mouse 746:Human 717:Amigo 335:Mouse 328:Human 275:Start 210:Mouse 174:Start 107:Human 78:21173 2167:PMID 2132:PMID 2089:PMID 2060:PMID 2025:PMID 1996:PMID 1961:PMID 1926:PMID 1875:PMID 1819:PMID 1776:PMID 1727:PMID 1686:PMID 1642:PMID 1593:PMID 1544:PMID 1495:PMID 1454:PMID 1387:PMID 1346:PMID 1272:PMID 1091:and 1073:gene 1062:ARP1 318:Bgee 266:Band 227:Chr. 165:Band 124:Chr. 58:OMIM 2157:doi 2122:PMC 2114:doi 2081:doi 2077:113 2050:doi 2017:doi 2013:112 1986:doi 1982:274 1951:doi 1916:PMC 1908:doi 1867:doi 1855:359 1811:doi 1799:411 1766:PMC 1758:doi 1754:176 1717:doi 1676:doi 1672:276 1632:PMC 1624:doi 1620:135 1583:PMC 1575:doi 1534:doi 1530:275 1485:doi 1444:PMC 1434:doi 1377:doi 1336:PMC 1328:doi 1324:126 1264:doi 1252:359 1127:or 1106:ATP 445:lip 288:End 187:End 90:OMA 66:MGI 2224:: 2173:. 2165:. 2151:. 2147:. 2130:. 2120:. 2110:10 2108:. 2104:. 2087:. 2075:. 2058:. 2044:. 2040:. 2023:. 2011:. 1994:. 1980:. 1976:. 1959:. 1945:. 1941:. 1924:. 1914:. 1902:. 1898:. 1881:. 1873:. 1865:. 1853:. 1825:. 1817:. 1809:. 1797:. 1774:. 1764:. 1752:. 1748:. 1725:. 1711:. 1707:. 1684:. 1670:. 1666:. 1654:^ 1640:. 1630:. 1618:. 1614:. 1591:. 1581:. 1571:14 1569:. 1565:. 1542:. 1528:. 1524:. 1501:. 1493:. 1479:. 1475:. 1452:. 1442:. 1432:. 1422:92 1420:. 1416:. 1393:. 1385:. 1371:. 1367:. 1344:. 1334:. 1322:. 1318:. 1292:^ 1278:. 1270:. 1262:. 1250:. 1231:. 1213:. 1184:^ 1163:^ 1151:. 1135:. 1075:. 719:/ 294:bp 281:bp 193:bp 180:bp 88:; 84:: 80:; 76:: 72:; 68:: 64:; 60:: 2214:. 2202:. 2181:. 2159:: 2153:1 2138:. 2116:: 2095:. 2083:: 2066:. 2052:: 2046:9 2031:. 2019:: 2002:. 1988:: 1967:. 1953:: 1947:7 1932:. 1910:: 1904:5 1889:. 1869:: 1861:: 1833:. 1813:: 1805:: 1782:. 1760:: 1733:. 1719:: 1713:7 1692:. 1678:: 1648:. 1626:: 1599:. 1577:: 1550:. 1536:: 1509:. 1487:: 1481:9 1460:. 1436:: 1428:: 1401:. 1379:: 1373:9 1352:. 1330:: 1303:. 1286:. 1266:: 1258:: 1235:. 1217:. 212:) 109:) 92::

Index

Aliases
ACTR1A
OMIM
605143
MGI
1858964
HomoloGene
21173
GeneCards
ACTR1A
OMA
ACTR1A - orthologs
Human
Chromosome 10 (human)
Chr.
Chromosome 10 (human)
Chromosome 10 (human)
Genomic location for ACTR1A
Genomic location for ACTR1A
Band
bp
bp
Mouse
Chromosome 19 (mouse)
Chr.
Chromosome 19 (mouse)
Genomic location for ACTR1A
Genomic location for ACTR1A
Band
bp

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