323:
300:
197:
222:
574:
42:
329:
228:
2747:
2732:
1437:
found that intravenous infusion of pituitary adenylate cyclase-activating polypeptide-38 induced migraine attacks in 58% of people with migraine, whilst the corresponding migraine induction rate was 55% for pituitary adenylate cyclase-activating polypeptide-27. Treatments with monoclonal antibodies
68:
2219:
Gourlet P, Vandermeers A, Robberecht P, Deschodt-Lanckman M (August 1997). "Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating peptide (PACAP-27, but not PACAP-38) degradation by the neutral endopeptidase EC 3.4.24.11".
2302:
Inooka H, Endo S, Kitada C, Mizuta E, Fujino M (November 1992). "Pituitary adenylate cyclase activating polypeptide (PACAP) with 27 residues. Conformation determined by 1H NMR and CD spectroscopies and distance geometry in 25% methanol solution".
1871:
1428:
Both isoforms of pituitary adenylate cyclase-activating polypeptide (pituitary adenylate cyclase-activating polypeptide-38 and pituitary adenylate cyclase-activating polypeptide-27) have been implicated in
2332:
Kimura C, Ohkubo S, Ogi K, Hosoya M, Itoh Y, Onda H, et al. (January 1990). "A novel peptide which stimulates adenylate cyclase: molecular cloning and characterization of the ovine and human cDNAs".
2484:
Vaudry D, Falluel-Morel A, Bourgault S, Basille M, Burel D, Wurtz O, et al. (September 2009). "Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery".
2058:
Dautzenberg FM, Mevenkamp G, Wille S, Hauger RL (December 1999). "N-terminal splice variants of the type I PACAP receptor: isolation, characterization and ligand binding/selectivity determinants".
2391:
Ohkubo S, Kimura C, Ogi K, Okazaki K, Hosoya M, Onda H, et al. (1992). "Primary structure and characterization of the precursor to human pituitary adenylate cyclase activating polypeptide".
3539:
1408:(PTSD) in women (but not men). This disorder involves a maladaptive psychological response to traumatic, i.e. existence-threatening, events. Ressler et al. identified an association of a
1899:"A phase 2, randomized, double-blind, placebo-controlled trial of AMG 301, a pituitary adenylate cyclase-activating polypeptide PAC1 receptor monoclonal antibody for migraine prevention"
1574:
Hosoya M, Kimura C, Ogi K, Ohkubo S, Miyamoto Y, Kugoh H, et al. (January 1992). "Structure of the human pituitary adenylate cyclase activating polypeptide (PACAP) gene".
2587:
Wray V, Kakoschke C, Nokihara K, Naruse S (June 1993). "Solution structure of pituitary adenylate cyclase activating polypeptide by nuclear magnetic resonance spectroscopy".
2169:
Felley CP, Qian JM, Mantey S, Pradhan T, Jensen RT (December 1992). "Chief cells possess a receptor with high affinity for PACAP and VIP that stimulates pepsinogen release".
1946:
Felley CP, Qian JM, Mantey S, Pradhan T, Jensen RT (December 1992). "Chief cells possess a receptor with high affinity for PACAP and VIP that stimulates pepsinogen release".
336:
235:
5454:
3532:
3501:
3288:
3161:
2251:"Cloning and functional characterization of a third pituitary adenylate cyclase-activating polypeptide receptor subtype expressed in insulin-secreting cells"
1357:
This gene encodes adenylate cyclase-activating polypeptide 1. Mediated by adenylate cyclase-activating polypeptide 1 receptors, this polypeptide stimulates
6070:
5218:
3354:
4835:
3525:
2679:
2455:
Pérez-Jurado LA, Francke U (June 1993). "Dinucleotide repeat polymorphism at the human pituitary adenylate cyclase activating polypeptide (PACAP) gene".
1365:
level in target cells. Adenylate cyclase-activating polypeptide 1 not only is a hypophysiotropic hormone (i.e. a substance that induces activity in the
1032:
4893:
1438:
have been investigated to target pituitary adenylate cyclase-activating polypeptide or its receptors for the treatment of primary headache disorders.
1013:
158:
5755:
5445:
5050:
2787:
4035:
3718:
1685:"Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) of the Bed Nucleus of the Stria Terminalis Mediates Heavy Alcohol Drinking in Mice"
1342:
6471:
6433:
6383:
6354:
6301:
4788:
4655:
2746:
2711:
2003:
1556:
6112:
6108:
6104:
6100:
3653:
3637:
1538:
1781:
Ghanizada H, Al-Karagholi MA, Arngrim N, Olesen J, Ashina M (January 2020). "PACAP27 induces migraine-like attacks in migraine patients".
322:
4381:
4300:
4167:
4084:
2731:
1417:
1397:, respectively; exon 4 encodes an adenylate cyclase-activating polypeptide 1-related peptide; and exon 5 encodes the mature peptide and
2521:
Waschek JA (2002). "Multiple actions of pituitary adenylyl cyclase activating peptide in nervous system development and regeneration".
6096:
3506:
3281:
1263:
299:
5785:
4904:
4464:
4075:
3326:
1256:
3733:
3677:
3668:
1612:
6307:
3151:
1525:
1504:
2666:
1412:
in the gene coding for pituitary adenylate cyclase-activating polypeptide (PACAP), implicating this peptide and its receptor (
6394:
6370:
5510:
5066:
4929:
1409:
1405:
1362:
221:
196:
1739:"pituitary adenylate cyclase-activating polypeptide-38 induces migraine-like attacks in patients with migraine without aura"
1628:"Post-traumatic stress disorder is associated with pituitary adenylate cyclase-activating polypeptide and the PAC1 receptor"
1521:
65:
6360:
3274:
1334:
2558:
Weber B, Riess O, Daneshvar H, Graham R, Hayden MR (June 1993). "(CA)n-dinucleotide repeat at the PDEB locus in 4p16.3".
2021:
Cross SH, Charlton JA, Nan X, Bird AP (March 1994). "Purification of CpG islands using a methylated DNA binding column".
1872:"Alder BioPharmaceuticals® Announces First-in-Human Dosing in Phase 1 ALD1910 Study for Preventive Treatment of Migraine"
1500:
6404:
4800:
4682:
4672:
3469:
3166:
138:
335:
234:
5750:
3438:
2780:
2362:
Nakata M, Yada T (2007). "PACAP in the glucose and energy homeostasis: physiological role and therapeutic potential".
1455:
5775:
328:
227:
6389:
4215:
3443:
1338:
5770:
6297:
3186:
2704:
4481:
4397:
4316:
4183:
4100:
2670:
1439:
1401:. This gene encodes three different mature peptides, including two isotypes: a shorter form and a longer form.
1077:
146:
3915:
6081:
3828:
3703:
1058:
5760:
1446:
AMG-301, which targets the PAC1 receptor, failed to show greater efficacy than placebo in phase II trials.
6365:
5981:
5885:
5745:
5505:
4924:
3910:
3548:
3464:
3346:
3236:
2773:
2422:"Purification and characterization of the receptor for pituitary adenylate cyclase-activating polypeptide"
6439:
4636:
4280:
3920:
3559:
210:
3266:
6379:
5765:
4697:
4646:
3305:
3211:
3206:
3196:
3181:
2697:
2262:
1639:
5515:
3590:
1988:
Endogenous ligands of PACAP/VIP receptors in the autocrine-paracrine regulation of the adrenal gland
5520:
4934:
4631:
3823:
3321:
3038:
1235:
1231:
1206:
1180:
1176:
1147:
125:
4556:
2845:
6138:
6051:
5996:
5950:
5895:
5630:
5570:
5198:
4571:
4501:
4060:
3658:
3600:
3551:
2870:
2546:
2509:
2157:
2120:
2083:
2046:
1806:
170:
6133:
6011:
5910:
5696:
5585:
5385:
5345:
5093:
5012:
4874:
4815:
4777:
4722:
4717:
4707:
4581:
4576:
4546:
4521:
4516:
4506:
4392:
4311:
4250:
4178:
4157:
4142:
4095:
3748:
1239:
1210:
1172:
1151:
6233:
6091:
6026:
6006:
5925:
5905:
5620:
5600:
5580:
5223:
4551:
4275:
3808:
3605:
1626:
Ressler KJ, Mercer KB, Bradley B, Jovanovic T, Mahan A, Kerley K, et al. (February 2011).
1416:) in PTSD. In mouse model of heavy alcohol drinking, PACAP seems to mediate alcohol effects on
6056:
6046:
6001:
5955:
5945:
5900:
5825:
5724:
5691:
5671:
5635:
5625:
5575:
5535:
5007:
4987:
4954:
4737:
4586:
2875:
2814:
2647:
2604:
2575:
2538:
2501:
2472:
2443:
2408:
2379:
2350:
2320:
2290:
2237:
2207:
2186:
2149:
2112:
2075:
2038:
2009:
1999:
1963:
1928:
1853:
1798:
1760:
1716:
1665:
1591:
1471:
1459:
1358:
573:
118:
58:
6016:
5915:
5810:
5714:
5666:
5659:
5645:
5590:
5560:
5040:
5030:
4982:
4964:
4727:
4566:
4511:
166:
6243:
5375:
2637:
2629:
2596:
2567:
2530:
2493:
2464:
2433:
2400:
2371:
2342:
2312:
2280:
2270:
2229:
2178:
2141:
2104:
2067:
2030:
1991:
1955:
1918:
1910:
1843:
1833:
1790:
1750:
1706:
1696:
1655:
1647:
1583:
1370:
415:
346:
290:
245:
4767:
5855:
3201:
2926:
2916:
1476:
1374:
1366:
390:
41:
2266:
1711:
1684:
1643:
6429:
6350:
6292:
5986:
5835:
5830:
4944:
4939:
3585:
3575:
3570:
3331:
3301:
3297:
3221:
3216:
2949:
2944:
2921:
2823:
2316:
1923:
1898:
1848:
1825:
1660:
1627:
1434:
1394:
2642:
2617:
2438:
2421:
2249:
Inagaki N, Yoshida H, Mizuta M, Mizuno N, Fujii Y, Gonoi T, et al. (March 1994).
2233:
1995:
947:
942:
937:
932:
927:
922:
917:
912:
907:
902:
897:
892:
887:
882:
877:
872:
867:
862:
857:
852:
847:
842:
837:
832:
827:
822:
817:
812:
807:
802:
797:
792:
787:
782:
777:
772:
767:
762:
757:
752:
747:
742:
737:
732:
727:
722:
717:
712:
707:
691:
686:
681:
676:
671:
666:
661:
645:
640:
635:
630:
625:
620:
615:
6465:
6123:
6036:
5965:
5935:
5870:
5780:
5734:
5610:
5540:
5485:
5474:
4959:
4667:
4350:
4255:
4147:
3448:
3313:
2898:
2893:
2860:
2683:
2616:
Zeng N, Athmann C, Kang T, Lyu RM, Walsh JH, Ohning GV, et al. (November 1999).
2346:
2285:
2250:
2071:
1810:
1587:
602:
3517:
2550:
2161:
2087:
2050:
1897:
Ashina M, Doležil D, Bonner JH, Zhou L, Klatt J, Picard H, Mikol DD (January 2021).
6449:
6419:
6158:
6148:
6041:
5940:
5795:
5615:
5550:
5465:
4969:
4772:
4611:
4606:
4526:
4476:
4290:
4044:
4025:
4004:
3975:
3698:
3693:
3494:
3489:
3484:
3479:
3226:
3102:
3097:
3092:
3087:
3054:
3049:
2800:
2513:
2124:
408:
187:
150:
2182:
1959:
2618:"PACAP type I receptor activation regulates ECL cells and gastric acid secretion"
174:
6409:
6375:
6273:
6263:
6258:
6248:
6198:
6021:
5920:
5681:
5595:
5525:
5420:
5183:
5148:
5098:
5061:
4997:
4879:
4810:
4762:
4752:
4747:
4742:
4626:
4621:
4616:
3994:
3905:
3895:
3863:
3858:
3853:
3848:
3838:
3798:
3763:
3231:
3141:
3069:
3044:
2980:
2965:
2885:
2855:
2840:
2420:
Ohtaki T, Masuda Y, Ishibashi Y, Kitada C, Arimura A, Fujino M (December 1993).
1701:
1561:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1543:
National Center for
Biotechnology Information, U.S. National Library of Medicine
2375:
2255:
Proceedings of the
National Academy of Sciences of the United States of America
2108:
2095:
Fahrenkrug J (2002). "Gut/brain peptides in the genital tract: VIP and PACAP".
491:
6228:
6193:
6188:
6178:
6168:
6086:
5875:
5850:
5840:
5686:
5640:
5500:
5326:
5295:
5264:
5233:
5178:
5153:
5133:
5118:
5108:
5002:
4919:
4712:
4692:
4591:
4536:
4531:
4355:
4260:
4245:
4040:
3999:
3971:
3940:
3900:
3803:
3758:
3753:
3728:
3723:
3713:
3626:
3620:
3610:
3474:
3246:
3033:
2997:
2987:
2970:
2936:
2908:
2865:
2145:
1443:
1442:'s ALD1910, which targets the peptide, began a phase I study in October 2019.
307:
204:
154:
1914:
1794:
1613:"Entrez Gene: ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)"
6253:
6223:
6218:
6213:
6208:
6203:
6183:
6173:
6163:
6153:
5845:
5805:
5701:
5676:
5435:
5430:
5425:
5415:
5410:
5405:
5395:
5316:
5254:
5188:
5168:
5163:
5158:
5143:
5138:
5128:
5123:
5017:
4992:
4757:
4677:
4596:
4541:
4431:
4370:
4360:
4265:
4152:
3950:
3945:
3935:
3843:
3833:
3818:
3793:
3788:
3778:
3773:
3768:
3422:
3417:
3412:
3407:
3402:
3397:
3392:
3387:
3369:
3364:
3171:
3156:
3002:
2992:
2975:
2832:
2468:
1737:
Schytz HW, Birk S, Wienecke T, Kruuse C, Olesen J, Ashina M (January 2009).
1382:
1378:
1346:
977:
778:
negative regulation of acute inflammatory response to non-antigenic stimulus
551:
429:
374:
361:
273:
260:
162:
2651:
2542:
2505:
2404:
2383:
2275:
2211:
2153:
2116:
2097:
Scandinavian
Journal of Clinical and Laboratory Investigation. Supplementum
2079:
2013:
1932:
1857:
1802:
1764:
1755:
1738:
1720:
1669:
1398:
1390:
2765:
2608:
2579:
2571:
2497:
2476:
2447:
2412:
2354:
2324:
2294:
2241:
2190:
2042:
1967:
1595:
1303:
1298:
6424:
6143:
5800:
5400:
5390:
5370:
5305:
5274:
5243:
5207:
5113:
5103:
4450:
3930:
3873:
3783:
3743:
3146:
3125:
3120:
3064:
1430:
1287:
1122:
1103:
928:
adenylate cyclase-activating G protein-coupled receptor signaling pathway
2600:
1651:
863:
negative regulation of acute inflammatory response to antigenic stimulus
6399:
5820:
5285:
4687:
3648:
3359:
3191:
3176:
2796:
2034:
1838:
1323:
1089:
1044:
17:
2534:
95:
91:
87:
6312:
5976:
5865:
5790:
5495:
5490:
4914:
4909:
4863:
4859:
4855:
4851:
4847:
4843:
4839:
4491:
4030:
3708:
3379:
3112:
1271:
999:
2633:
1576:
Biochimica et
Biophysica Acta (BBA) - Gene Structure and Expression
1333:. pituitary adenylate cyclase-activating polypeptide is similar to
636:
pituitary adenylate cyclase-activating polypeptide receptor binding
6344:
6340:
6336:
6332:
6328:
6324:
6320:
6316:
6031:
5930:
5605:
5545:
5359:
5082:
5078:
5074:
5070:
4561:
4425:
4344:
4340:
4239:
4235:
4231:
4227:
4136:
4132:
3983:
3025:
1990:. International Review of Cytology. Vol. 249. pp. 1–51.
1454:
Pituitary adenylate cyclase-activating peptide has been shown to
962:
958:
5815:
4421:
4417:
4413:
4409:
4405:
4401:
4336:
4332:
4328:
4324:
4320:
4223:
4219:
4211:
4207:
4203:
4199:
4195:
4191:
4187:
4128:
4124:
4120:
4116:
4112:
4108:
4104:
4056:
4052:
4048:
4014:
3979:
3960:
3336:
1413:
1386:
1330:
808:
positive regulation of chemokine (C-C motif) ligand 5 production
142:
3521:
3270:
2769:
2693:
3251:
2689:
582:
1826:"Emerging Treatment Targets for Migraine and Other Headaches"
2132:
Fahrenkrug J (2006). "PACAP--a multifacetted neuropeptide".
1347:
pituitary adenylate cyclase-activating polypeptide receptor
803:
positive regulation of synaptic transmission, glutamatergic
616:
pituitary adenylate cyclase activating polypeptide activity
903:
positive regulation of cytosolic calcium ion concentration
718:
regulation of G protein-coupled receptor signaling pathway
1385:
regulation of certain types of cells. This gene has five
888:
positive regulation of transcription by RNA polymerase II
398:
6415:
Pituitary adenylate cyclase-activating peptide (PACAP)
2755:: Pac1-Rshort N-terminal EC domain Pacap(6-38) complex
783:
regulation of oligodendrocyte progenitor proliferation
2305:
International
Journal of Peptide and Protein Research
563:
838:
positive regulation of neuron projection development
818:
positive regulation of cell population proliferation
743:
negative regulation of muscle cell apoptotic process
6282:
6069:
5964:
5733:
5473:
5464:
5444:
5358:
5335:
5304:
5273:
5242:
5206:
5197:
5049:
4892:
4825:
4787:
4654:
4645:
4463:
4440:
4380:
4299:
4166:
4083:
4074:
4013:
3959:
3872:
3676:
3667:
3636:
3558:
3457:
3431:
3378:
3345:
3312:
3134:
3111:
3080:
3024:
3015:
2958:
2935:
2907:
2884:
2831:
2822:
2807:
2335:
1224:
1199:
1165:
1140:
129:, PACAP, adenylate cyclase activating polypeptide 1
6361:Glucose-6-phosphate isomerase (GPI; PGI, PHI, AMF)
5219:Glial cell line-derived neurotrophic factor (GDNF)
4872:Cleavage products/derivatives with unknown target:
2667:Pituitary+adenylate+cyclase-activating+polypeptide
1517:
1515:
1513:
1496:
1494:
1492:
1316:Pituitary adenylate cyclase-activating polypeptide
2740:: The solution structure of micelle-bound peptide
1433:pathogenesis. A Danish research group led by Dr.
948:positive regulation of cold-induced thermogenesis
345:
244:
6395:Macrophage-stimulating protein (MSP; HLP, HGFLP)
1404:A version of this gene has been associated with
4036:Heparin-binding EGF-like growth factor (HB-EGF)
3719:Heparin-binding EGF-like growth factor (HB-EGF)
913:positive regulation of growth hormone secretion
833:positive regulation of interleukin-6 production
723:negative regulation of glial cell proliferation
27:Protein-coding gene in the species Homo sapiens
3242:Pituitary adenylate cyclase-activating peptide
1986:Conconi MT, Spinazzi R, Nussdorfer GG (2006).
1522:GRCm38: Ensembl release 89: ENSMUSG00000024256
933:positive regulation of cAMP-mediated signaling
893:positive regulation of protein kinase activity
823:negative regulation of potassium ion transport
6447:Additional growth factor receptor modulators:
3533:
3282:
3162:Cocaine- and amphetamine-regulated transcript
2781:
2705:
883:positive regulation of somatostatin secretion
813:regulation of postsynaptic membrane potential
8:
4801:Insulin-like growth factor-2 (somatomedin A)
4683:Insulin-like growth factor-2 (somatomedin A)
4673:Insulin-like growth factor-1 (somatomedin C)
923:G protein-coupled receptor signaling pathway
828:positive regulation of ERK1 and ERK2 cascade
788:cellular response to glucocorticoid stimulus
1501:GRCh38: Ensembl release 89: ENSG00000141433
5470:
5203:
4651:
4080:
3673:
3540:
3526:
3518:
3289:
3275:
3267:
3021:
2828:
2788:
2774:
2766:
2712:
2698:
2690:
2680:United States National Library of Medicine
973:
598:
386:
285:
182:
76:
2669:at the U.S. National Library of Medicine
2641:
2437:
2284:
2274:
1922:
1847:
1837:
1754:
1710:
1700:
1659:
918:regulation of signaling receptor activity
6405:Migration-stimulating factor (MSF; PRG4)
2678:This article incorporates text from the
1607:
1605:
758:activation of adenylate cyclase activity
3734:Transforming growth factor alpha (TGFα)
2727:
1488:
6308:Connective tissue growth factor (CTGF)
1343:vasoactive intestinal peptide receptor
798:negative regulation of GTPase activity
793:positive regulation of gene expression
768:positive regulation of GTPase activity
31:
6371:Hepatoma-derived growth factor (HDGF)
2622:The Journal of Clinical Investigation
1776:
1774:
1683:Lauren Lepeak ... (1 December 2023).
1337:. One of its effects is to stimulate
898:regulation of protein phosphorylation
350:
311:
306:
249:
208:
203:
7:
1732:
1730:
2426:The Journal of Biological Chemistry
1824:Bertels Z, Pradhan AA (July 2019).
1418:bed nucleus of the stria terminalis
2317:10.1111/j.1399-3011.1992.tb00324.x
2171:The American Journal of Physiology
1948:The American Journal of Physiology
1377:. In addition, it plays a role in
1221:
1196:
1162:
1137:
1113:
1094:
1068:
1049:
1023:
1004:
763:regulation of protein localization
662:intracellular anatomical structure
568:
530:central gray substance of midbrain
486:
424:
403:
25:
2198:Geng L, Ju G (January 1997). "".
1326:that in humans is encoded by the
738:negative regulation of cell cycle
6390:Leukemia inhibitory factor (LIF)
2745:
2730:
2072:10.1046/j.1365-2826.1999.00411.x
1878:. GlobeNewswire. 10 October 2019
626:peptide hormone receptor binding
572:
518:dorsomedial hypothalamic nucleus
334:
327:
321:
298:
233:
226:
220:
195:
40:
5558:Negative allosteric modulators:
3152:Calcitonin gene-related peptide
1361:and subsequently increases the
5876:Gossypetin (3,5,7,8,3',4'-HHF)
5067:Platelet-derived growth factor
1406:post-traumatic stress disorder
868:neuropeptide signaling pathway
583:More reference expression data
552:More reference expression data
1:
6082:Placental growth factor (PGF)
2439:10.1016/S0021-9258(19)74361-0
2364:Current Pharmaceutical Design
2234:10.1016/S0006-2952(97)00207-4
2183:10.1152/ajpgi.1992.263.6.G901
2060:Journal of Neuroendocrinology
1996:10.1016/S0074-7696(06)49001-X
1960:10.1152/ajpgi.1992.263.6.G901
1335:vasoactive intestinal peptide
873:neuron projection development
641:neuropeptide hormone activity
319:
218:
6472:Genes on human chromosome 18
6366:Glia maturation factor (GMF)
4875:Glypromate (GPE, (1-3)IGF-1)
3167:Delta-sleep-inducing peptide
2347:10.1016/0006-291X(90)91914-E
1588:10.1016/0167-4781(92)90488-l
848:ovarian follicle development
2134:Chronobiology International
1702:10.1523/ENEURO.0424-23.2023
1389:. Exons 1 and 2 encode the
1369:), but also functions as a
1339:enterochromaffin-like cells
943:camera-type eye development
713:pituitary gland development
6488:
6298:Colony-stimulating factors
6290:Additional growth factors:
2523:Developmental Neuroscience
2376:10.2174/138161207780618948
2109:10.1080/003655101317095392
1832:. 59 Suppl 2 (S2): 50–65.
853:sensory perception of pain
753:nervous system development
646:signaling receptor binding
5646:SNA-120 (pegylated K252a)
4818:(against IGF-1 and IGF-2)
4780:(against IGF-1 and IGF-2)
3187:Gastrin-releasing peptide
2725:
2200:Sheng Li Ke Xue Jin Zhan
2146:10.1080/07420520500464569
1557:"Mouse PubMed Reference:"
1539:"Human PubMed Reference:"
1302:
1297:
1293:
1286:
1270:
1251:
1228:
1203:
1192:
1169:
1144:
1133:
1120:
1116:
1101:
1097:
1088:
1075:
1071:
1056:
1052:
1043:
1030:
1026:
1011:
1007:
998:
983:
976:
972:
956:
601:
597:
580:
571:
562:
549:
498:
489:
472:anterior cingulate cortex
436:
427:
397:
389:
385:
368:
355:
318:
297:
288:
284:
267:
254:
217:
194:
185:
181:
136:
133:
123:
116:
111:
84:
79:
62:
57:
52:
48:
39:
34:
4482:Hepatocyte growth factor
4041:Neuregulins (heregulins)
3972:Neuregulins (heregulins)
3916:Trastuzumab duocarmazine
3629:(against angiopoietin 2)
3623:(against angiopoietin 3)
2671:Medical Subject Headings
2560:Human Molecular Genetics
2457:Human Molecular Genetics
2222:Biochemical Pharmacology
1915:10.1177/0333102420970889
1795:10.1177/0333102419864507
1440:Alder BioPharmaceuticals
1264:Chr 17: 93.51 – 93.51 Mb
748:behavioral fear response
3829:Depatuxizumab mafodotin
2486:Pharmacological Reviews
1876:Globenewswire News Room
878:cAMP-mediated signaling
6452:(neurotrophin mixture)
6440:Wnt signaling proteins
6121:Allosteric modulators:
5841:Norwogonin (5,7,8-THF)
4061:5 (tomoregulin, TMEFF)
3911:Trastuzumab deruxtecan
3549:Growth factor receptor
3237:Pancreatic polypeptide
2405:10.1089/dna.1992.11.21
2276:10.1073/pnas.91.7.2679
843:response to starvation
538:superior frontal gyrus
514:ventral tegmental area
502:lumbar spinal ganglion
6380:T-cell growth factors
4637:Telisotuzumab vedotin
3921:Trastuzumab emtansine
2498:10.1124/pr.109.001370
2469:10.1093/hmg/2.6.827-a
1257:Chr 18: 0.9 – 0.91 Mb
773:ATP metabolic process
534:primary visual cortex
313:Chromosome 17 (mouse)
211:Chromosome 18 (human)
4965:EVT-901 (SAR-127963)
4698:Mecasermin rinfabate
3306:Neurotrophic factors
3182:Galanin-like peptide
2393:DNA and Cell Biology
1756:10.1093/brain/awn307
667:extracellular region
510:ventromedial nucleus
80:List of PDB id codes
53:Available structures
2601:10.1021/bi00073a016
2572:10.1093/hmg/2.6.827
2267:1994PNAS...91.2679I
1652:10.1038/nature09856
1644:2011Natur.470..492R
858:response to ethanol
733:cell-cell signaling
708:histamine secretion
677:extracellular space
522:trigeminal ganglion
468:ganglionic eminence
175:ADCYAP1 - orthologs
6131:Kinase inhibitors:
5994:Kinase inhibitors:
5893:Kinase inhibitors:
5568:Kinase inhibitors:
5383:Kinase inhibitors:
5343:Kinase inhibitors:
5324:Kinase inhibitors:
5293:Kinase inhibitors:
5262:Kinase inhibitors:
5231:Kinase inhibitors:
5091:Kinase inhibitors:
4705:Kinase inhibitors:
4499:Kinase inhibitors:
4288:Kinase inhibitors:
4281:Aprutumab ixadotin
3928:Kinase inhibitors:
3741:Kinase inhibitors:
3598:Kinase inhibitors:
2682:, which is in the
2177:(6 Pt 1): G901-7.
2035:10.1038/ng0394-236
1954:(6 Pt 1): G901-7.
1839:10.1111/head.13585
1424:Headache Disorders
1078:ENSMUSG00000024256
701:Biological process
655:Cellular component
609:Molecular function
476:right frontal lobe
6459:
6458:
6065:
6064:
5826:N-Acetylserotonin
5725:ReN-1820 (TrkAd5)
5354:
5353:
4888:
4887:
4833:Binding proteins:
4492:Dihexa (PNB-0408)
4459:
4458:
4070:
4069:
3984:6 (neuroglycan C)
3704:EGF (urogastrone)
3682:
3515:
3514:
3264:
3263:
3260:
3259:
3011:
3010:
2763:
2762:
2535:10.1159/000064942
2005:978-0-12-364653-8
1472:Adenylate cyclase
1460:secretin receptor
1359:adenylate cyclase
1313:
1312:
1309:
1308:
1282:
1281:
1247:
1246:
1218:
1217:
1188:
1187:
1159:
1158:
1129:
1128:
1110:
1109:
1084:
1083:
1065:
1064:
1039:
1038:
1020:
1019:
968:
967:
938:brain development
908:insulin secretion
682:neuron projection
593:
592:
589:
588:
558:
557:
545:
544:
483:
482:
452:prefrontal cortex
381:
380:
280:
279:
107:
106:
103:
102:
63:Ortholog search:
16:(Redirected from
6479:
6271:Decoy receptors:
6244:Alacizumab pegol
5722:Decoy receptors:
5471:
5376:Stem cell factor
5317:Persephin (PSPN)
5255:Neurturin (NRTN)
5204:
5041:LEVI-04 (p75-Fc)
5038:Decoy receptors:
4652:
4081:
3680:
3674:
3542:
3535:
3528:
3519:
3291:
3284:
3277:
3268:
3022:
2829:
2790:
2783:
2776:
2767:
2749:
2734:
2714:
2707:
2700:
2691:
2655:
2645:
2612:
2583:
2554:
2517:
2480:
2451:
2441:
2416:
2387:
2358:
2328:
2298:
2288:
2278:
2245:
2215:
2194:
2165:
2128:
2091:
2054:
2017:
1972:
1971:
1943:
1937:
1936:
1926:
1894:
1888:
1887:
1885:
1883:
1868:
1862:
1861:
1851:
1841:
1821:
1815:
1814:
1778:
1769:
1768:
1758:
1734:
1725:
1724:
1714:
1704:
1680:
1674:
1673:
1663:
1623:
1617:
1616:
1609:
1600:
1599:
1571:
1565:
1564:
1553:
1547:
1546:
1535:
1529:
1519:
1508:
1498:
1371:neurotransmitter
1295:
1294:
1266:
1259:
1242:
1222:
1213:
1197:
1193:RefSeq (protein)
1183:
1163:
1154:
1138:
1114:
1095:
1069:
1050:
1024:
1005:
974:
728:female pregnancy
621:hormone activity
599:
585:
576:
569:
554:
494:
492:Top expressed in
487:
432:
430:Top expressed in
425:
404:
387:
377:
364:
353:
338:
331:
325:
314:
302:
286:
276:
263:
252:
237:
230:
224:
213:
199:
183:
177:
128:
121:
98:
77:
71:
50:
49:
44:
32:
21:
6487:
6486:
6482:
6481:
6480:
6478:
6477:
6476:
6462:
6461:
6460:
6455:
6400:Midkine (NEGF2)
6278:
6061:
5960:
5729:
5667:ABT-110 (PG110)
5460:
5440:
5350:
5331:
5300:
5269:
5238:
5193:
5045:
4983:ABT-110 (PG110)
4884:
4821:
4783:
4641:
4455:
4436:
4376:
4373:(against FGF23)
4295:
4162:
4066:
4009:
3955:
3868:
3679:
3663:
3632:
3554:
3546:
3516:
3511:
3453:
3427:
3374:
3341:
3308:
3295:
3265:
3256:
3212:Neuropeptide VF
3207:Neuropeptide SF
3202:Neuropeptide FF
3197:Neuropeptide AF
3130:
3107:
3076:
3017:
3007:
2954:
2931:
2903:
2880:
2849:
2824:Opioid peptides
2818:
2803:
2794:
2764:
2759:
2756:
2750:
2741:
2735:
2721:
2718:
2663:
2658:
2634:10.1172/JCI7537
2628:(10): 1383–91.
2615:
2595:(22): 5832–41.
2586:
2557:
2520:
2483:
2454:
2432:(35): 26650–7.
2419:
2390:
2370:(11): 1105–12.
2361:
2331:
2301:
2248:
2218:
2197:
2168:
2131:
2094:
2057:
2023:Nature Genetics
2020:
2006:
1985:
1981:
1979:Further reading
1976:
1975:
1945:
1944:
1940:
1896:
1895:
1891:
1881:
1879:
1870:
1869:
1865:
1823:
1822:
1818:
1780:
1779:
1772:
1749:(Pt 1): 16–25.
1736:
1735:
1728:
1682:
1681:
1677:
1638:(7335): 492–7.
1625:
1624:
1620:
1611:
1610:
1603:
1573:
1572:
1568:
1555:
1554:
1550:
1537:
1536:
1532:
1520:
1511:
1499:
1490:
1485:
1477:Pituitary gland
1468:
1452:
1426:
1355:
1304:View/Edit Mouse
1299:View/Edit Human
1262:
1255:
1252:Location (UCSC)
1238:
1234:
1230:
1209:
1205:
1179:
1175:
1171:
1150:
1146:
1059:ENSG00000141433
952:
696:
692:cell body fiber
672:terminal bouton
650:
631:protein binding
581:
550:
541:
536:
532:
528:
524:
520:
516:
512:
508:
506:mammillary body
504:
490:
479:
474:
470:
466:
464:cingulate gyrus
462:
458:
456:Brodmann area 9
454:
450:
446:
442:
428:
372:
359:
351:
341:
340:
339:
332:
312:
289:Gene location (
271:
258:
250:
240:
239:
238:
231:
209:
186:Gene location (
137:
124:
117:
86:
64:
28:
23:
22:
15:
12:
11:
5:
6485:
6483:
6475:
6474:
6464:
6463:
6457:
6456:
6454:
6453:
6443:
6442:
6437:
6430:Thrombopoietin
6427:
6422:
6417:
6412:
6407:
6402:
6397:
6392:
6387:
6373:
6368:
6363:
6358:
6351:Erythropoietin
6348:
6310:
6305:
6295:
6293:Adrenomedullin
6286:
6284:
6280:
6279:
6277:
6276:
6267:
6266:
6261:
6256:
6251:
6246:
6237:
6236:
6231:
6226:
6221:
6216:
6211:
6206:
6201:
6196:
6191:
6186:
6181:
6176:
6171:
6166:
6161:
6156:
6151:
6146:
6141:
6136:
6127:
6126:
6117:
6116:
6094:
6089:
6084:
6075:
6073:
6067:
6066:
6063:
6062:
6060:
6059:
6054:
6049:
6044:
6039:
6034:
6029:
6024:
6019:
6014:
6009:
6004:
5999:
5990:
5989:
5984:
5979:
5970:
5968:
5962:
5961:
5959:
5958:
5953:
5948:
5943:
5938:
5933:
5928:
5923:
5918:
5913:
5908:
5903:
5898:
5889:
5888:
5879:
5878:
5873:
5868:
5859:
5858:
5853:
5848:
5843:
5838:
5833:
5828:
5823:
5818:
5813:
5808:
5803:
5798:
5793:
5788:
5783:
5778:
5773:
5768:
5763:
5758:
5756:4'-DMA-7,8-DHF
5753:
5748:
5739:
5737:
5731:
5730:
5728:
5727:
5718:
5717:
5705:
5704:
5699:
5694:
5689:
5684:
5679:
5674:
5669:
5650:
5649:
5643:
5638:
5633:
5628:
5623:
5618:
5613:
5608:
5603:
5598:
5593:
5588:
5583:
5578:
5573:
5564:
5563:
5554:
5553:
5548:
5543:
5538:
5529:
5528:
5523:
5518:
5516:Gambogic amide
5513:
5508:
5503:
5498:
5493:
5488:
5479:
5477:
5468:
5462:
5461:
5459:
5458:
5450:
5448:
5442:
5441:
5439:
5438:
5433:
5428:
5423:
5418:
5413:
5408:
5403:
5398:
5393:
5388:
5379:
5378:
5373:
5364:
5362:
5356:
5355:
5352:
5351:
5349:
5348:
5339:
5337:
5333:
5332:
5330:
5329:
5320:
5319:
5310:
5308:
5302:
5301:
5299:
5298:
5289:
5288:
5286:Artemin (ARTN)
5279:
5277:
5271:
5270:
5268:
5267:
5258:
5257:
5248:
5246:
5240:
5239:
5237:
5236:
5227:
5226:
5221:
5212:
5210:
5201:
5195:
5194:
5192:
5191:
5186:
5181:
5172:
5171:
5166:
5161:
5156:
5151:
5146:
5141:
5136:
5131:
5126:
5121:
5116:
5111:
5106:
5101:
5096:
5087:
5086:
5064:
5055:
5053:
5047:
5046:
5044:
5043:
5034:
5033:
5021:
5020:
5015:
5010:
5005:
5000:
4995:
4990:
4985:
4973:
4972:
4967:
4962:
4957:
4948:
4947:
4942:
4937:
4932:
4927:
4922:
4917:
4912:
4907:
4898:
4896:
4890:
4889:
4886:
4885:
4883:
4882:
4877:
4868:
4867:
4829:
4827:
4823:
4822:
4820:
4819:
4813:
4804:
4803:
4793:
4791:
4785:
4784:
4782:
4781:
4775:
4770:
4765:
4760:
4755:
4750:
4745:
4740:
4731:
4730:
4725:
4720:
4715:
4710:
4701:
4700:
4695:
4690:
4685:
4680:
4675:
4670:
4660:
4658:
4649:
4643:
4642:
4640:
4639:
4634:
4629:
4624:
4619:
4614:
4609:
4600:
4599:
4594:
4589:
4584:
4579:
4574:
4569:
4564:
4559:
4554:
4549:
4544:
4539:
4534:
4529:
4524:
4519:
4514:
4509:
4504:
4495:
4494:
4485:
4484:
4479:
4469:
4467:
4461:
4460:
4457:
4456:
4454:
4453:
4444:
4442:
4438:
4437:
4435:
4434:
4429:
4395:
4386:
4384:
4378:
4377:
4375:
4374:
4364:
4363:
4358:
4353:
4348:
4314:
4305:
4303:
4297:
4296:
4294:
4293:
4284:
4283:
4278:
4269:
4268:
4263:
4258:
4253:
4248:
4243:
4181:
4172:
4170:
4164:
4163:
4161:
4160:
4155:
4150:
4145:
4140:
4098:
4089:
4087:
4078:
4072:
4071:
4068:
4067:
4065:
4064:
4038:
4033:
4028:
4019:
4017:
4011:
4010:
4008:
4007:
4002:
3997:
3988:
3987:
3965:
3963:
3957:
3956:
3954:
3953:
3948:
3943:
3938:
3933:
3924:
3923:
3918:
3913:
3908:
3903:
3898:
3889:
3888:
3878:
3876:
3870:
3869:
3867:
3866:
3861:
3856:
3851:
3846:
3841:
3836:
3831:
3826:
3821:
3812:
3811:
3806:
3801:
3796:
3791:
3786:
3781:
3776:
3771:
3766:
3761:
3756:
3751:
3746:
3737:
3736:
3731:
3726:
3721:
3716:
3711:
3706:
3701:
3696:
3686:
3684:
3671:
3665:
3664:
3662:
3661:
3656:
3651:
3642:
3640:
3634:
3633:
3631:
3630:
3624:
3614:
3613:
3608:
3603:
3594:
3593:
3591:Angiopoietin 3
3588:
3586:Angiopoietin 2
3579:
3578:
3576:Angiopoietin 4
3573:
3571:Angiopoietin 1
3564:
3562:
3556:
3555:
3547:
3545:
3544:
3537:
3530:
3522:
3513:
3512:
3510:
3509:
3504:
3499:
3498:
3497:
3492:
3487:
3482:
3472:
3467:
3461:
3459:
3455:
3454:
3452:
3451:
3446:
3441:
3435:
3433:
3429:
3428:
3426:
3425:
3420:
3415:
3410:
3405:
3400:
3395:
3390:
3384:
3382:
3376:
3375:
3373:
3372:
3367:
3362:
3357:
3351:
3349:
3343:
3342:
3340:
3339:
3334:
3329:
3324:
3318:
3316:
3310:
3309:
3302:Nervous tissue
3298:Cell signaling
3296:
3294:
3293:
3286:
3279:
3271:
3262:
3261:
3258:
3257:
3255:
3254:
3249:
3244:
3239:
3234:
3229:
3224:
3222:Neuropeptide Y
3219:
3217:Neuropeptide S
3214:
3209:
3204:
3199:
3194:
3189:
3184:
3179:
3174:
3169:
3164:
3159:
3154:
3149:
3144:
3138:
3136:
3132:
3131:
3129:
3128:
3123:
3117:
3115:
3109:
3108:
3106:
3105:
3100:
3095:
3090:
3084:
3082:
3078:
3077:
3075:
3074:
3073:
3072:
3067:
3059:
3058:
3057:
3052:
3047:
3036:
3030:
3028:
3019:
3013:
3012:
3009:
3008:
3006:
3005:
3000:
2995:
2990:
2985:
2984:
2983:
2973:
2968:
2962:
2960:
2956:
2955:
2953:
2952:
2950:Leu-enkephalin
2947:
2945:Met-enkephalin
2941:
2939:
2933:
2932:
2930:
2929:
2924:
2919:
2913:
2911:
2905:
2904:
2902:
2901:
2896:
2890:
2888:
2882:
2881:
2879:
2878:
2876:β-Neoendorphin
2873:
2871:α-Neoendorphin
2868:
2863:
2858:
2853:
2852:
2851:
2847:
2837:
2835:
2826:
2820:
2819:
2811:
2809:
2805:
2804:
2795:
2793:
2792:
2785:
2778:
2770:
2761:
2760:
2758:
2757:
2751:
2744:
2742:
2736:
2729:
2726:
2723:
2722:
2719:
2717:
2716:
2709:
2702:
2694:
2675:
2674:
2662:
2661:External links
2659:
2657:
2656:
2613:
2584:
2555:
2518:
2492:(3): 283–357.
2481:
2452:
2417:
2388:
2359:
2329:
2299:
2261:(7): 2679–83.
2246:
2216:
2195:
2166:
2140:(1–2): 53–61.
2129:
2092:
2055:
2018:
2004:
1982:
1980:
1977:
1974:
1973:
1938:
1889:
1863:
1816:
1770:
1726:
1675:
1618:
1601:
1582:(2): 199–206.
1566:
1548:
1530:
1509:
1487:
1486:
1484:
1481:
1480:
1479:
1474:
1467:
1464:
1451:
1448:
1435:Messoud Ashina
1425:
1422:
1395:signal peptide
1375:neuromodulator
1354:
1351:
1341:. It binds to
1318:also known as
1311:
1310:
1307:
1306:
1301:
1291:
1290:
1284:
1283:
1280:
1279:
1277:
1275:
1268:
1267:
1260:
1253:
1249:
1248:
1245:
1244:
1226:
1225:
1219:
1216:
1215:
1201:
1200:
1194:
1190:
1189:
1186:
1185:
1167:
1166:
1160:
1157:
1156:
1142:
1141:
1135:
1131:
1130:
1127:
1126:
1118:
1117:
1111:
1108:
1107:
1099:
1098:
1092:
1086:
1085:
1082:
1081:
1073:
1072:
1066:
1063:
1062:
1054:
1053:
1047:
1041:
1040:
1037:
1036:
1028:
1027:
1021:
1018:
1017:
1009:
1008:
1002:
996:
995:
990:
985:
981:
980:
970:
969:
966:
965:
954:
953:
951:
950:
945:
940:
935:
930:
925:
920:
915:
910:
905:
900:
895:
890:
885:
880:
875:
870:
865:
860:
855:
850:
845:
840:
835:
830:
825:
820:
815:
810:
805:
800:
795:
790:
785:
780:
775:
770:
765:
760:
755:
750:
745:
740:
735:
730:
725:
720:
715:
710:
704:
702:
698:
697:
695:
694:
689:
684:
679:
674:
669:
664:
658:
656:
652:
651:
649:
648:
643:
638:
633:
628:
623:
618:
612:
610:
606:
605:
595:
594:
591:
590:
587:
586:
578:
577:
566:
560:
559:
556:
555:
547:
546:
543:
542:
540:
539:
535:
531:
527:
523:
519:
515:
511:
507:
503:
499:
496:
495:
484:
481:
480:
478:
477:
473:
469:
465:
461:
457:
453:
449:
445:
441:
437:
434:
433:
421:
420:
412:
401:
395:
394:
391:RNA expression
383:
382:
379:
378:
370:
366:
365:
357:
354:
349:
343:
342:
333:
326:
320:
316:
315:
310:
304:
303:
295:
294:
282:
281:
278:
277:
269:
265:
264:
256:
253:
248:
242:
241:
232:
225:
219:
215:
214:
207:
201:
200:
192:
191:
179:
178:
135:
131:
130:
122:
114:
113:
109:
108:
105:
104:
101:
100:
82:
81:
73:
72:
61:
55:
54:
46:
45:
37:
36:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
6484:
6473:
6470:
6469:
6467:
6451:
6448:
6445:
6444:
6441:
6438:
6435:
6431:
6428:
6426:
6423:
6421:
6418:
6416:
6413:
6411:
6408:
6406:
6403:
6401:
6398:
6396:
6393:
6391:
6388:
6385:
6381:
6377:
6374:
6372:
6369:
6367:
6364:
6362:
6359:
6356:
6352:
6349:
6346:
6342:
6338:
6334:
6330:
6326:
6322:
6318:
6314:
6311:
6309:
6306:
6303:
6299:
6296:
6294:
6291:
6288:
6287:
6285:
6281:
6275:
6272:
6269:
6268:
6265:
6262:
6260:
6257:
6255:
6252:
6250:
6247:
6245:
6242:
6239:
6238:
6235:
6232:
6230:
6227:
6225:
6222:
6220:
6217:
6215:
6212:
6210:
6207:
6205:
6202:
6200:
6197:
6195:
6192:
6190:
6187:
6185:
6182:
6180:
6177:
6175:
6172:
6170:
6167:
6165:
6162:
6160:
6157:
6155:
6152:
6150:
6147:
6145:
6142:
6140:
6137:
6135:
6132:
6129:
6128:
6125:
6124:Cyclotraxin B
6122:
6119:
6118:
6114:
6110:
6106:
6102:
6098:
6095:
6093:
6090:
6088:
6085:
6083:
6080:
6077:
6076:
6074:
6072:
6068:
6058:
6055:
6053:
6050:
6048:
6045:
6043:
6040:
6038:
6037:Larotrectinib
6035:
6033:
6030:
6028:
6025:
6023:
6020:
6018:
6015:
6013:
6010:
6008:
6005:
6003:
6000:
5998:
5995:
5992:
5991:
5988:
5985:
5983:
5980:
5978:
5975:
5972:
5971:
5969:
5967:
5963:
5957:
5954:
5952:
5949:
5947:
5944:
5942:
5939:
5937:
5936:Larotrectinib
5934:
5932:
5929:
5927:
5924:
5922:
5919:
5917:
5914:
5912:
5909:
5907:
5904:
5902:
5899:
5897:
5894:
5891:
5890:
5887:
5884:
5881:
5880:
5877:
5874:
5872:
5871:Cyclotraxin B
5869:
5867:
5864:
5861:
5860:
5857:
5854:
5852:
5849:
5847:
5844:
5842:
5839:
5837:
5834:
5832:
5829:
5827:
5824:
5822:
5819:
5817:
5814:
5812:
5809:
5807:
5804:
5802:
5799:
5797:
5794:
5792:
5789:
5787:
5784:
5782:
5781:Amitriptyline
5779:
5777:
5774:
5772:
5769:
5767:
5764:
5762:
5759:
5757:
5754:
5752:
5749:
5747:
5744:
5741:
5740:
5738:
5736:
5732:
5726:
5723:
5720:
5719:
5716:
5713:
5710:
5707:
5706:
5703:
5700:
5698:
5695:
5693:
5690:
5688:
5685:
5683:
5680:
5678:
5675:
5673:
5670:
5668:
5665:
5661:
5658:
5657:Against TrkA:
5655:
5652:
5651:
5647:
5644:
5642:
5639:
5637:
5634:
5632:
5629:
5627:
5624:
5622:
5619:
5617:
5614:
5612:
5611:Larotrectinib
5609:
5607:
5604:
5602:
5599:
5597:
5594:
5592:
5589:
5587:
5584:
5582:
5579:
5577:
5574:
5572:
5569:
5566:
5565:
5562:
5559:
5556:
5555:
5552:
5549:
5547:
5544:
5542:
5541:Dexamethasone
5539:
5537:
5534:
5531:
5530:
5527:
5524:
5522:
5519:
5517:
5514:
5512:
5509:
5507:
5504:
5502:
5499:
5497:
5494:
5492:
5489:
5487:
5486:Amitriptyline
5484:
5481:
5480:
5478:
5476:
5472:
5469:
5467:
5463:
5456:
5452:
5451:
5449:
5447:
5443:
5437:
5434:
5432:
5429:
5427:
5424:
5422:
5419:
5417:
5414:
5412:
5409:
5407:
5404:
5402:
5399:
5397:
5394:
5392:
5389:
5387:
5384:
5381:
5380:
5377:
5374:
5372:
5369:
5366:
5365:
5363:
5361:
5357:
5347:
5344:
5341:
5340:
5338:
5334:
5328:
5325:
5322:
5321:
5318:
5315:
5312:
5311:
5309:
5307:
5303:
5297:
5294:
5291:
5290:
5287:
5284:
5281:
5280:
5278:
5276:
5272:
5266:
5263:
5260:
5259:
5256:
5253:
5250:
5249:
5247:
5245:
5241:
5235:
5232:
5229:
5228:
5225:
5222:
5220:
5217:
5214:
5213:
5211:
5209:
5205:
5202:
5200:
5196:
5190:
5187:
5185:
5182:
5180:
5177:
5174:
5173:
5170:
5167:
5165:
5162:
5160:
5157:
5155:
5152:
5150:
5147:
5145:
5142:
5140:
5137:
5135:
5132:
5130:
5127:
5125:
5122:
5120:
5117:
5115:
5112:
5110:
5107:
5105:
5102:
5100:
5097:
5095:
5092:
5089:
5088:
5084:
5080:
5076:
5072:
5068:
5065:
5063:
5060:
5057:
5056:
5054:
5052:
5048:
5042:
5039:
5036:
5035:
5032:
5029:
5026:
5023:
5022:
5019:
5016:
5014:
5011:
5009:
5006:
5004:
5001:
4999:
4996:
4994:
4991:
4989:
4986:
4984:
4981:
4978:
4975:
4974:
4971:
4968:
4966:
4963:
4961:
4960:Dexamethasone
4958:
4956:
4953:
4950:
4949:
4946:
4943:
4941:
4938:
4936:
4933:
4931:
4928:
4926:
4923:
4921:
4918:
4916:
4913:
4911:
4908:
4906:
4903:
4900:
4899:
4897:
4895:
4891:
4881:
4878:
4876:
4873:
4870:
4869:
4865:
4861:
4857:
4853:
4849:
4845:
4841:
4837:
4834:
4831:
4830:
4828:
4824:
4817:
4814:
4812:
4809:
4806:
4805:
4802:
4798:
4795:
4794:
4792:
4790:
4786:
4779:
4776:
4774:
4771:
4769:
4766:
4764:
4761:
4759:
4756:
4754:
4751:
4749:
4746:
4744:
4741:
4739:
4736:
4733:
4732:
4729:
4726:
4724:
4721:
4719:
4716:
4714:
4711:
4709:
4706:
4703:
4702:
4699:
4696:
4694:
4691:
4689:
4686:
4684:
4681:
4679:
4676:
4674:
4671:
4669:
4668:des(1-3)IGF-1
4665:
4662:
4661:
4659:
4657:
4653:
4650:
4648:
4644:
4638:
4635:
4633:
4632:Telisotuzumab
4630:
4628:
4625:
4623:
4620:
4618:
4615:
4613:
4610:
4608:
4605:
4602:
4601:
4598:
4595:
4593:
4590:
4588:
4585:
4583:
4580:
4578:
4575:
4573:
4570:
4568:
4565:
4563:
4560:
4558:
4555:
4553:
4550:
4548:
4545:
4543:
4540:
4538:
4535:
4533:
4530:
4528:
4525:
4523:
4520:
4518:
4515:
4513:
4510:
4508:
4505:
4503:
4500:
4497:
4496:
4493:
4490:
4489:Potentiators:
4487:
4486:
4483:
4480:
4478:
4474:
4471:
4470:
4468:
4466:
4462:
4452:
4449:
4446:
4445:
4443:
4439:
4433:
4430:
4427:
4423:
4419:
4415:
4411:
4407:
4403:
4399:
4396:
4394:
4391:
4388:
4387:
4385:
4383:
4379:
4372:
4369:
4366:
4365:
4362:
4359:
4357:
4354:
4352:
4351:Selpercatinib
4349:
4346:
4342:
4338:
4334:
4330:
4326:
4322:
4318:
4315:
4313:
4310:
4307:
4306:
4304:
4302:
4298:
4292:
4289:
4286:
4285:
4282:
4279:
4277:
4274:
4271:
4270:
4267:
4264:
4262:
4259:
4257:
4256:Selpercatinib
4254:
4252:
4249:
4247:
4244:
4241:
4237:
4233:
4229:
4225:
4221:
4217:
4213:
4209:
4205:
4201:
4197:
4193:
4189:
4185:
4182:
4180:
4177:
4174:
4173:
4171:
4169:
4165:
4159:
4156:
4154:
4151:
4149:
4148:Selpercatinib
4146:
4144:
4141:
4138:
4134:
4130:
4126:
4122:
4118:
4114:
4110:
4106:
4102:
4099:
4097:
4094:
4091:
4090:
4088:
4086:
4082:
4079:
4077:
4073:
4062:
4058:
4054:
4050:
4046:
4042:
4039:
4037:
4034:
4032:
4029:
4027:
4024:
4021:
4020:
4018:
4016:
4012:
4006:
4003:
4001:
3998:
3996:
3993:
3990:
3989:
3985:
3981:
3977:
3973:
3970:
3967:
3966:
3964:
3962:
3958:
3952:
3949:
3947:
3944:
3942:
3939:
3937:
3934:
3932:
3929:
3926:
3925:
3922:
3919:
3917:
3914:
3912:
3909:
3907:
3904:
3902:
3899:
3897:
3894:
3891:
3890:
3887:
3883:
3880:
3879:
3877:
3875:
3871:
3865:
3862:
3860:
3857:
3855:
3852:
3850:
3847:
3845:
3842:
3840:
3837:
3835:
3832:
3830:
3827:
3825:
3824:Depatuxizumab
3822:
3820:
3817:
3814:
3813:
3810:
3807:
3805:
3802:
3800:
3797:
3795:
3792:
3790:
3787:
3785:
3782:
3780:
3777:
3775:
3772:
3770:
3767:
3765:
3762:
3760:
3757:
3755:
3752:
3750:
3747:
3745:
3742:
3739:
3738:
3735:
3732:
3730:
3727:
3725:
3722:
3720:
3717:
3715:
3712:
3710:
3707:
3705:
3702:
3700:
3697:
3695:
3691:
3688:
3687:
3685:
3683:
3675:
3672:
3670:
3666:
3660:
3657:
3655:
3652:
3650:
3647:
3644:
3643:
3641:
3639:
3635:
3628:
3625:
3622:
3619:
3616:
3615:
3612:
3609:
3607:
3604:
3602:
3599:
3596:
3595:
3592:
3589:
3587:
3584:
3581:
3580:
3577:
3574:
3572:
3569:
3566:
3565:
3563:
3561:
3557:
3553:
3550:
3543:
3538:
3536:
3531:
3529:
3524:
3523:
3520:
3508:
3505:
3503:
3500:
3496:
3493:
3491:
3488:
3486:
3483:
3481:
3478:
3477:
3476:
3473:
3471:
3468:
3466:
3463:
3462:
3460:
3456:
3450:
3447:
3445:
3442:
3440:
3437:
3436:
3434:
3430:
3424:
3421:
3419:
3416:
3414:
3411:
3409:
3406:
3404:
3401:
3399:
3396:
3394:
3391:
3389:
3386:
3385:
3383:
3381:
3377:
3371:
3368:
3366:
3363:
3361:
3358:
3356:
3353:
3352:
3350:
3348:
3344:
3338:
3335:
3333:
3330:
3328:
3325:
3323:
3320:
3319:
3317:
3315:
3314:Neurotrophins
3311:
3307:
3303:
3299:
3292:
3287:
3285:
3280:
3278:
3273:
3272:
3269:
3253:
3250:
3248:
3245:
3243:
3240:
3238:
3235:
3233:
3230:
3228:
3225:
3223:
3220:
3218:
3215:
3213:
3210:
3208:
3205:
3203:
3200:
3198:
3195:
3193:
3190:
3188:
3185:
3183:
3180:
3178:
3175:
3173:
3170:
3168:
3165:
3163:
3160:
3158:
3155:
3153:
3150:
3148:
3145:
3143:
3140:
3139:
3137:
3133:
3127:
3124:
3122:
3119:
3118:
3116:
3114:
3110:
3104:
3101:
3099:
3096:
3094:
3091:
3089:
3086:
3085:
3083:
3079:
3071:
3068:
3066:
3063:
3062:
3060:
3056:
3053:
3051:
3048:
3046:
3043:
3042:
3040:
3037:
3035:
3032:
3031:
3029:
3027:
3023:
3020:
3018:neuropeptides
3014:
3004:
3001:
2999:
2996:
2994:
2991:
2989:
2986:
2982:
2979:
2978:
2977:
2974:
2972:
2969:
2967:
2964:
2963:
2961:
2957:
2951:
2948:
2946:
2943:
2942:
2940:
2938:
2934:
2928:
2925:
2923:
2920:
2918:
2915:
2914:
2912:
2910:
2906:
2900:
2899:Endomorphin-2
2897:
2895:
2894:Endomorphin-1
2892:
2891:
2889:
2887:
2883:
2877:
2874:
2872:
2869:
2867:
2864:
2862:
2861:Big dynorphin
2859:
2857:
2854:
2850:
2844:
2843:
2842:
2839:
2838:
2836:
2834:
2830:
2827:
2825:
2821:
2817:
2816:
2810:
2806:
2802:
2801:neuropeptides
2798:
2791:
2786:
2784:
2779:
2777:
2772:
2771:
2768:
2754:
2748:
2743:
2739:
2733:
2728:
2724:
2715:
2710:
2708:
2703:
2701:
2696:
2695:
2692:
2688:
2687:
2685:
2684:public domain
2681:
2672:
2668:
2665:
2664:
2660:
2653:
2649:
2644:
2639:
2635:
2631:
2627:
2623:
2619:
2614:
2610:
2606:
2602:
2598:
2594:
2590:
2585:
2581:
2577:
2573:
2569:
2565:
2561:
2556:
2552:
2548:
2544:
2540:
2536:
2532:
2528:
2524:
2519:
2515:
2511:
2507:
2503:
2499:
2495:
2491:
2487:
2482:
2478:
2474:
2470:
2466:
2462:
2458:
2453:
2449:
2445:
2440:
2435:
2431:
2427:
2423:
2418:
2414:
2410:
2406:
2402:
2398:
2394:
2389:
2385:
2381:
2377:
2373:
2369:
2365:
2360:
2356:
2352:
2348:
2344:
2340:
2336:
2330:
2326:
2322:
2318:
2314:
2311:(5): 456–64.
2310:
2306:
2300:
2296:
2292:
2287:
2282:
2277:
2272:
2268:
2264:
2260:
2256:
2252:
2247:
2243:
2239:
2235:
2231:
2228:(4): 509–15.
2227:
2223:
2217:
2213:
2209:
2205:
2201:
2196:
2192:
2188:
2184:
2180:
2176:
2172:
2167:
2163:
2159:
2155:
2151:
2147:
2143:
2139:
2135:
2130:
2126:
2122:
2118:
2114:
2110:
2106:
2103:(234): 35–9.
2102:
2098:
2093:
2089:
2085:
2081:
2077:
2073:
2069:
2066:(12): 941–9.
2065:
2061:
2056:
2052:
2048:
2044:
2040:
2036:
2032:
2029:(3): 236–44.
2028:
2024:
2019:
2015:
2011:
2007:
2001:
1997:
1993:
1989:
1984:
1983:
1978:
1969:
1965:
1961:
1957:
1953:
1949:
1942:
1939:
1934:
1930:
1925:
1920:
1916:
1912:
1908:
1904:
1900:
1893:
1890:
1877:
1873:
1867:
1864:
1859:
1855:
1850:
1845:
1840:
1835:
1831:
1827:
1820:
1817:
1812:
1808:
1804:
1800:
1796:
1792:
1788:
1784:
1777:
1775:
1771:
1766:
1762:
1757:
1752:
1748:
1744:
1740:
1733:
1731:
1727:
1722:
1718:
1713:
1708:
1703:
1698:
1694:
1690:
1686:
1679:
1676:
1671:
1667:
1662:
1657:
1653:
1649:
1645:
1641:
1637:
1633:
1629:
1622:
1619:
1614:
1608:
1606:
1602:
1597:
1593:
1589:
1585:
1581:
1577:
1570:
1567:
1562:
1558:
1552:
1549:
1544:
1540:
1534:
1531:
1527:
1523:
1518:
1516:
1514:
1510:
1506:
1502:
1497:
1495:
1493:
1489:
1482:
1478:
1475:
1473:
1470:
1469:
1465:
1463:
1461:
1457:
1449:
1447:
1445:
1441:
1436:
1432:
1423:
1421:
1419:
1415:
1411:
1407:
1402:
1400:
1396:
1392:
1388:
1384:
1380:
1376:
1372:
1368:
1364:
1360:
1352:
1350:
1348:
1344:
1340:
1336:
1332:
1329:
1325:
1321:
1317:
1305:
1300:
1296:
1292:
1289:
1285:
1278:
1276:
1273:
1269:
1265:
1261:
1258:
1254:
1250:
1243:
1241:
1237:
1233:
1227:
1223:
1220:
1214:
1212:
1208:
1202:
1198:
1195:
1191:
1184:
1182:
1178:
1174:
1168:
1164:
1161:
1155:
1153:
1149:
1143:
1139:
1136:
1134:RefSeq (mRNA)
1132:
1125:
1124:
1119:
1115:
1112:
1106:
1105:
1100:
1096:
1093:
1091:
1087:
1080:
1079:
1074:
1070:
1067:
1061:
1060:
1055:
1051:
1048:
1046:
1042:
1035:
1034:
1029:
1025:
1022:
1016:
1015:
1010:
1006:
1003:
1001:
997:
994:
991:
989:
986:
982:
979:
975:
971:
964:
960:
955:
949:
946:
944:
941:
939:
936:
934:
931:
929:
926:
924:
921:
919:
916:
914:
911:
909:
906:
904:
901:
899:
896:
894:
891:
889:
886:
884:
881:
879:
876:
874:
871:
869:
866:
864:
861:
859:
856:
854:
851:
849:
846:
844:
841:
839:
836:
834:
831:
829:
826:
824:
821:
819:
816:
814:
811:
809:
806:
804:
801:
799:
796:
794:
791:
789:
786:
784:
781:
779:
776:
774:
771:
769:
766:
764:
761:
759:
756:
754:
751:
749:
746:
744:
741:
739:
736:
734:
731:
729:
726:
724:
721:
719:
716:
714:
711:
709:
706:
705:
703:
700:
699:
693:
690:
688:
685:
683:
680:
678:
675:
673:
670:
668:
665:
663:
660:
659:
657:
654:
653:
647:
644:
642:
639:
637:
634:
632:
629:
627:
624:
622:
619:
617:
614:
613:
611:
608:
607:
604:
603:Gene ontology
600:
596:
584:
579:
575:
570:
567:
565:
561:
553:
548:
537:
533:
529:
525:
521:
517:
513:
509:
505:
501:
500:
497:
493:
488:
485:
475:
471:
467:
463:
459:
455:
451:
447:
443:
439:
438:
435:
431:
426:
423:
422:
419:
417:
413:
411:
410:
406:
405:
402:
400:
396:
392:
388:
384:
376:
371:
367:
363:
358:
352:17|17 E5
348:
344:
337:
330:
324:
317:
309:
305:
301:
296:
292:
287:
283:
275:
270:
266:
262:
257:
247:
243:
236:
229:
223:
216:
212:
206:
202:
198:
193:
189:
184:
180:
176:
172:
168:
164:
160:
156:
152:
148:
144:
140:
132:
127:
120:
115:
110:
99:
97:
93:
89:
83:
78:
75:
74:
70:
67:
60:
56:
51:
47:
43:
38:
33:
30:
19:
6450:Cerebrolysin
6446:
6420:Pleiotrophin
6414:
6376:Interleukins
6289:
6270:
6240:
6159:Fruquintinib
6149:Cabozantinib
6130:
6120:
6078:
6042:Lestaurtinib
5993:
5973:
5941:Lestaurtinib
5892:
5882:
5863:Antagonists:
5862:
5796:Deoxygedunin
5751:3,7,8,2'-THF
5742:
5721:
5712:Against NGF:
5711:
5708:
5664:Against NGF:
5663:
5656:
5653:
5616:Lestaurtinib
5567:
5557:
5551:Testosterone
5533:Antagonists:
5532:
5482:
5382:
5367:
5342:
5323:
5313:
5292:
5282:
5261:
5251:
5230:
5215:
5175:
5090:
5058:
5037:
5028:Against NGF:
5027:
5024:
4980:Against NGF:
4979:
4976:
4970:Testosterone
4952:Antagonists:
4951:
4901:
4871:
4832:
4807:
4796:
4773:Teprotumumab
4734:
4704:
4663:
4612:Ficlatuzumab
4607:Emibetuzumab
4603:
4557:JNJ-38877605
4527:Cabozantinib
4498:
4488:
4477:Fosgonimeton
4472:
4447:
4389:
4367:
4308:
4291:Infigratinib
4287:
4272:
4175:
4092:
4026:Betacellulin
4022:
4005:Seribantumab
3991:
3968:
3927:
3892:
3886:Unknown/none
3885:
3881:
3815:
3740:
3699:Betacellulin
3694:Amphiregulin
3689:
3681:(ErbB1/HER1)
3645:
3617:
3597:
3583:Antagonists:
3582:
3567:
3560:Angiopoietin
3241:
3227:Neurophysins
3055:Neurokinin B
3050:Neurokinin A
2886:Endomorphins
2812:
2752:
2737:
2677:
2676:
2625:
2621:
2592:
2589:Biochemistry
2588:
2563:
2559:
2529:(1): 14–23.
2526:
2522:
2489:
2485:
2460:
2456:
2429:
2425:
2399:(1): 21–30.
2396:
2392:
2367:
2363:
2338:
2334:
2308:
2304:
2258:
2254:
2225:
2221:
2206:(1): 29–34.
2203:
2199:
2174:
2170:
2137:
2133:
2100:
2096:
2063:
2059:
2026:
2022:
1987:
1951:
1947:
1941:
1909:(1): 33–44.
1906:
1902:
1892:
1880:. Retrieved
1875:
1866:
1829:
1819:
1789:(1): 57–67.
1786:
1782:
1746:
1742:
1692:
1688:
1678:
1635:
1631:
1621:
1579:
1575:
1569:
1560:
1551:
1542:
1533:
1453:
1450:Interactions
1427:
1403:
1356:
1327:
1319:
1315:
1314:
1236:NP_001302433
1232:NP_001302432
1229:
1207:NP_001093203
1204:
1181:NM_001315504
1177:NM_001315503
1170:
1148:NM_001099733
1145:
1121:
1102:
1076:
1057:
1031:
1012:
992:
987:
448:hypothalamus
414:
407:
134:External IDs
85:
29:
6410:Oncomodulin
6274:Aflibercept
6264:Ranibizumab
6259:Ramucirumab
6249:Bevacizumab
6241:Antibodies:
6199:Regorafenib
6139:Altiratinib
6052:ONO-5390556
6022:Entrectinib
5997:Altiratinib
5951:ONO-5390556
5921:Entrectinib
5896:Altiratinib
5682:Frunevetmab
5654:Antibodies:
5631:ONO-5390556
5596:Entrectinib
5571:Altiratinib
5526:Tavilermide
5421:Quizartinib
5360:SCF (c-Kit)
5184:Ramucirumab
5176:Antibodies:
5149:Quizartinib
5099:Avapritinib
5062:Becaplermin
4998:Frunevetmab
4977:Antibodies:
4880:Trofinetide
4811:Dusigitumab
4808:Antibodies:
4763:Robatumumab
4753:Figitumumab
4748:Dalotuzumab
4743:Cixutumumab
4735:Antibodies:
4627:Rilotumumab
4622:Onartuzumab
4617:Flanvotumab
4604:Antibodies:
4572:PF-04217903
4502:Altiratinib
4465:HGF (c-Met)
4368:Antibodies:
4273:Antibodies:
3995:Duligotumab
3992:Antibodies:
3906:Trastuzumab
3896:Ertumaxomab
3893:Antibodies:
3864:Zalutumumab
3859:Panitumumab
3854:Nimotuzumab
3849:Necitumumab
3839:Imgatuzumab
3816:Antibodies:
3799:Osimertinib
3764:Dacomitinib
3659:Dapiclermin
3618:Antibodies:
3601:Altiratinib
3475:Neuregulins
3432:CNTF family
3347:GDNF family
3232:Neurotensin
3142:Angiotensin
3081:Neuromedins
3070:Physalaemin
3045:Substance P
3039:Tachykinins
3034:Bradykinins
2981:Hemorphin-4
2966:Adrenorphin
2937:Enkephalins
2927:γ-Endorphin
2922:β-Endorphin
2917:α-Endorphin
2856:Dynorphin B
2846:Dynorphin A
2841:Dynorphin A
2720:PDB gallery
2341:(1): 81–9.
1903:Cephalalgia
1783:Cephalalgia
1345:and to the
460:gallbladder
373:93,513,965
360:93,506,445
112:Identifiers
6229:Vandetanib
6194:Rebastinib
6189:Pegaptanib
6179:Nintedanib
6169:Lenvatinib
6134:Agerafenib
6087:Ripretinib
6012:CH-7057288
5911:CH-7057288
5776:7,8,3'-THF
5771:7,8,2'-THF
5697:Ranevetmab
5687:Fulranumab
5641:Rebastinib
5586:CH-7057288
5501:Cenegermin
5386:Agerafenib
5346:Agerafenib
5327:Vandetanib
5296:Vandetanib
5265:Vandetanib
5234:Vandetanib
5179:Olaratumab
5154:Ripretinib
5134:Nintedanib
5119:Lenvatinib
5109:Crenolanib
5094:Agerafenib
5013:Ranevetmab
5003:Fulranumab
4920:Cenegermin
4894:LNGF (p75)
4816:Xentuzumab
4778:Xentuzumab
4723:NVP-AEW541
4718:NVP-ADW742
4713:Linsitinib
4708:BMS-754807
4693:Mecasermin
4592:Tivantinib
4582:PHA-665752
4577:PF-2341066
4547:Golvatinib
4537:Crizotinib
4532:Capmatinib
4522:BMS-777607
4517:Amuvatinib
4393:Ersofermin
4356:Sprifermin
4312:Ersofermin
4261:Sprifermin
4251:Repifermin
4246:Palifermin
4179:Ersofermin
4158:Velafermin
4143:Repifermin
4096:Ersofermin
4015:ErbB4/HER4
4000:Patritumab
3961:ErbB3/HER3
3941:Mubritinib
3901:Pertuzumab
3874:ErbB2/HER2
3804:Vandetanib
3759:Canertinib
3754:Brigatinib
3749:Agerafenib
3729:Nepidermin
3724:Murodermin
3714:Epiregulin
3669:EGF (ErbB)
3627:Nesvacumab
3621:Evinacumab
3611:Rebastinib
3552:modulators
3061:amphibian
2998:Spinorphin
2988:Nociceptin
2971:Amidorphin
2909:Endorphins
2866:Leumorphin
2833:Dynorphins
2566:(6): 827.
2463:(6): 827.
1882:10 October
1528:, May 2017
1507:, May 2017
1483:References
1367:hypophysis
687:perikaryon
418:(ortholog)
155:HomoloGene
6254:Icrucumab
6234:WHI-P 154
6224:Tivozanib
6219:Toceranib
6214:Sunitinib
6209:Sorafenib
6204:Semaxanib
6184:Pazopanib
6174:Motesanib
6164:Lapatinib
6154:Cediranib
6092:Telbermin
6079:Agonists:
6027:GZ-389988
6007:CE-245677
5974:Agonists:
5926:GZ-389988
5906:CE-245677
5806:Diosmetin
5743:Agonists:
5709:Aptamers:
5702:Tanezumab
5677:Fasinumab
5621:Milciclib
5601:GZ-389988
5581:CE-245677
5483:Agonists:
5436:Toceranib
5431:Sunitinib
5426:Sorafenib
5416:Pazopanib
5411:Nilotinib
5406:Masitinib
5396:Dasatinib
5368:Agonists:
5314:Agonists:
5283:Agonists:
5252:Agonists:
5224:Liatermin
5216:Agonists:
5199:RET (GFL)
5189:Tovetumab
5169:Toceranib
5164:Sorafenib
5159:Sunitinib
5144:Radotinib
5139:Pazopanib
5129:Motesanib
5124:Masitinib
5059:Agonists:
5025:Aptamers:
5018:Tanezumab
4993:Fasinumab
4902:Agonists:
4758:Ganitumab
4678:IGF-1 LR3
4597:Volitinib
4552:INCB28060
4542:Foretinib
4448:Agonists:
4432:Trafermin
4390:Agonists:
4371:Burosumab
4361:Trafermin
4309:Agonists:
4276:Aprutumab
4266:Trafermin
4228:10 (KGF2)
4176:Agonists:
4153:Trafermin
4133:10 (KGF2)
4093:Agonists:
4023:Agonists:
3969:Agonists:
3951:Tucatinib
3946:Neratinib
3936:Lapatinib
3844:Matuzumab
3834:Futuximab
3819:Cetuximab
3809:WHI-P 154
3794:Neratinib
3789:Lapatinib
3779:Grandinin
3774:Gefitinib
3769:Erlotinib
3646:Agonists:
3606:CE-245677
3568:Agonists:
3370:Persephin
3365:Neurturin
3172:FMRFamide
3157:Carnosine
3041:: mammal
3003:Valorphin
2993:Opiorphin
2976:Hemorphin
1811:196349669
1383:autocrine
1379:paracrine
1240:NP_033755
1211:NP_001108
1173:NM_009625
1152:NM_001117
978:Orthologs
440:beta cell
163:GeneCards
6466:Category
6436:instead)
6425:Renalase
6386:instead)
6357:instead)
6304:instead)
6144:Axitinib
6113:D (FIGF)
6057:PLX-7486
6047:ONO-4474
6002:AZD-6918
5956:PLX-7486
5946:ONO-4474
5901:AZD-6918
5883:Ligands:
5801:Deprenyl
5761:7,3'-DHF
5692:MEDI-578
5672:ASP-6294
5636:PLX-7486
5626:ONO-4474
5576:AZD-6918
5536:ALE-0540
5457:instead.
5401:Imatinib
5391:Axitinib
5371:Ancestim
5336:Unsorted
5114:Imatinib
5104:Axitinib
5008:MEDI-578
4988:ASP-6294
4955:ALE-0540
4797:Agonists
4738:AVE-1642
4664:Agonists
4587:SU-11274
4473:Agonists
4451:FGF15/19
4441:Unsorted
4406:2 (bFGF)
4325:2 (bFGF)
4192:2 (bFGF)
4109:2 (bFGF)
3931:Afatinib
3882:Agonists
3784:Icotinib
3744:Afatinib
3690:Agonists
3147:Bombesin
3065:Kassinin
2815:hormones
2808:Hormones
2797:Peptides
2652:10562300
2551:22281905
2543:12145407
2506:19805477
2384:17430174
2212:10921074
2162:29584195
2154:16687279
2117:11713978
2088:35761617
2080:10583729
2051:12847618
2014:16697281
1933:33231489
1858:31291018
1830:Headache
1803:31299857
1765:19052139
1721:38053471
1712:10755645
1670:21350482
1524:–
1503:–
1466:See also
1456:interact
1431:migraine
1353:Function
1288:Wikidata
957:Sources:
526:habenula
272:912,172
259:904,871
251:18p11.32
6313:Ephrins
6017:DS-6051
5916:DS-6051
5821:LM22A-4
5811:DMAQ-B1
5766:7,8-DHF
5746:3,7-DHF
5715:RBM-004
5660:GBR-900
5591:DS-6051
5561:VM-902A
5031:RBM-004
4728:OSl-906
4688:Insulin
4567:MK-2461
4512:AMG-458
3649:Axokine
3380:Ephrins
3360:Artemin
3247:RVD-Hpα
3192:Ghrelin
3177:Galanin
3113:Orexins
2609:8504103
2580:8394765
2514:5739004
2477:8353512
2448:8253796
2413:1739432
2355:2302217
2325:1483839
2295:8146174
2263:Bibcode
2242:9313778
2191:1335692
2125:7249967
2043:8012384
1968:1335692
1924:7786389
1849:6986366
1661:3046811
1640:Bibcode
1596:1730060
1526:Ensembl
1505:Ensembl
1444:Amgen's
1328:ADCYAP1
1324:protein
1090:UniProt
1045:Ensembl
984:Species
963:QuickGO
393:pattern
167:ADCYAP1
126:ADCYAP1
119:Aliases
35:ADCYAP1
18:ADCYAP1
6283:Others
5977:BNN-20
5866:ANA-12
5791:BNN-20
5511:DHEA-S
5496:BNN-27
5491:BNN-20
4930:DHEA-S
4915:BNN-27
4910:BNN-20
4826:Others
4031:Epigen
3709:Epigen
3026:Kinins
2959:Others
2673:(MeSH)
2650:
2643:409843
2640:
2607:
2578:
2549:
2541:
2512:
2504:
2475:
2446:
2411:
2382:
2353:
2323:
2293:
2283:
2240:
2210:
2189:
2160:
2152:
2123:
2115:
2086:
2078:
2049:
2041:
2012:
2002:
1966:
1931:
1921:
1856:
1846:
1809:
1801:
1763:
1719:
1709:
1695:(12).
1689:eNeuro
1668:
1658:
1632:Nature
1594:
1399:3' UTR
1391:5' UTR
1274:search
1272:PubMed
1123:O70176
1104:P18509
1000:Entrez
564:BioGPS
151:105094
143:102980
6432:(see
6382:(see
6353:(see
6300:(see
6032:K252a
5931:K252a
5606:K252a
5546:FX007
5306:GFRα4
5275:GFRα3
5244:GFRα2
5208:GFRα1
4836:IGFBP
4789:IGF-2
4768:R1507
4656:IGF-1
4562:K252a
4382:FGFR4
4301:FGFR3
4168:FGFR2
4085:FGFR1
3502:PACAP
3470:IGF-1
3458:Other
3135:Other
3016:Other
2547:S2CID
2510:S2CID
2286:43433
2158:S2CID
2121:S2CID
2084:S2CID
2047:S2CID
1807:S2CID
1743:Brain
1458:with
1387:exons
1322:is a
1320:PACAP
1033:11516
993:Mouse
988:Human
959:Amigo
444:gonad
416:Mouse
409:Human
356:Start
291:Mouse
255:Start
188:Human
6434:here
6384:here
6355:here
6302:here
6097:VEGF
6071:VEGF
5987:NT-3
5982:DHEA
5966:TrkC
5886:DHEA
5856:TDP6
5836:NT-4
5831:NT-3
5816:HIOC
5786:BDNF
5735:TrkB
5506:DHEA
5475:TrkA
5455:here
5453:See
5446:TGFβ
5051:PDGF
4945:NT-4
4940:NT-3
4925:DHEA
4905:BDNF
3654:CNTF
3638:CNTF
3507:VEGF
3449:IL-6
3439:CNTF
3355:GDNF
3337:NT-4
3332:NT-3
3327:BDNF
2813:see
2753:2jod
2738:2d2p
2648:PMID
2605:PMID
2576:PMID
2539:PMID
2502:PMID
2473:PMID
2444:PMID
2409:PMID
2380:PMID
2351:PMID
2321:PMID
2291:PMID
2238:PMID
2208:PMID
2187:PMID
2150:PMID
2113:PMID
2076:PMID
2039:PMID
2010:PMID
2000:ISBN
1964:PMID
1929:PMID
1884:2019
1854:PMID
1799:PMID
1761:PMID
1717:PMID
1666:PMID
1592:PMID
1580:1129
1414:PAC1
1393:and
1381:and
1373:and
1363:cAMP
1331:gene
399:Bgee
347:Band
308:Chr.
246:Band
205:Chr.
139:OMIM
96:2JOD
92:2D2P
88:1GEA
69:RCSB
66:PDBe
5851:R13
5521:NGF
5466:Trk
4935:NGF
4647:IGF
4507:AM7
4398:FGF
4317:FGF
4218:),
4216:KGF
4184:FGF
4101:FGF
4076:FGF
3678:EGF
3465:GMF
3444:LIF
3322:NGF
3252:VGF
2848:1–8
2638:PMC
2630:doi
2626:104
2597:doi
2568:doi
2531:doi
2494:doi
2465:doi
2434:doi
2430:268
2401:doi
2372:doi
2343:doi
2339:166
2313:doi
2281:PMC
2271:doi
2230:doi
2179:doi
2175:263
2142:doi
2105:doi
2068:doi
2031:doi
1992:doi
1956:doi
1952:263
1919:PMC
1911:doi
1844:PMC
1834:doi
1791:doi
1751:doi
1747:132
1707:PMC
1697:doi
1656:PMC
1648:doi
1636:470
1584:doi
1410:SNP
1014:116
369:End
268:End
171:OMA
159:869
147:MGI
59:PDB
6468::
6345:B3
6343:,
6341:B2
6339:,
6337:B1
6335:,
6333:A5
6331:,
6329:A4
6327:,
6325:A3
6323:,
6321:A2
6319:,
6317:A1
6111:,
6107:,
6103:,
5846:R7
5662:;
5081:,
5077:,
5073:,
4862:,
4858:,
4854:,
4850:,
4846:,
4842:,
4799::
4666::
4475::
4426:19
4424:,
4420:,
4416:,
4412:,
4408:,
4404:,
4345:23
4343:,
4341:18
4339:,
4335:,
4331:,
4327:,
4323:,
4240:22
4238:,
4236:18
4234:,
4232:17
4230:,
4226:,
4222:,
4210:,
4206:,
4202:,
4198:,
4194:,
4190:,
4137:20
4135:,
4131:,
4127:,
4123:,
4119:,
4115:,
4111:,
4107:,
4059:,
4055:,
4051:,
4047:,
3982:,
3978:,
3884::
3692::
3423:B3
3418:B2
3413:B1
3408:A5
3403:A4
3398:A3
3393:A2
3388:A1
3304::
3300::
2799::
2646:.
2636:.
2624:.
2620:.
2603:.
2593:32
2591:.
2574:.
2562:.
2545:.
2537:.
2527:24
2525:.
2508:.
2500:.
2490:61
2488:.
2471:.
2459:.
2442:.
2428:.
2424:.
2407:.
2397:11
2395:.
2378:.
2368:13
2366:.
2349:.
2337:.
2319:.
2309:40
2307:.
2289:.
2279:.
2269:.
2259:91
2257:.
2253:.
2236:.
2226:54
2224:.
2204:28
2202:.
2185:.
2173:.
2156:.
2148:.
2138:23
2136:.
2119:.
2111:.
2101:61
2099:.
2082:.
2074:.
2064:11
2062:.
2045:.
2037:.
2025:.
2008:.
1998:.
1962:.
1950:.
1927:.
1917:.
1907:41
1905:.
1901:.
1874:.
1852:.
1842:.
1828:.
1805:.
1797:.
1787:40
1785:.
1773:^
1759:.
1745:.
1741:.
1729:^
1715:.
1705:.
1693:10
1691:.
1687:.
1664:.
1654:.
1646:.
1634:.
1630:.
1604:^
1590:.
1578:.
1559:.
1541:.
1512:^
1491:^
1462:.
1420:.
1349:.
961:/
375:bp
362:bp
274:bp
261:bp
169:;
165::
161:;
157::
153:;
149::
145:;
141::
94:,
90:,
6378:/
6347:)
6315:(
6115:)
6109:C
6105:B
6101:A
6099:(
5648:)
5085:)
5083:D
5079:C
5075:B
5071:A
5069:(
4866:)
4864:7
4860:6
4856:5
4852:4
4848:3
4844:2
4840:1
4838:(
4428:)
4422:9
4418:8
4414:6
4410:4
4402:1
4400:(
4347:)
4337:9
4333:8
4329:4
4321:1
4319:(
4242:)
4224:9
4220:8
4214:(
4212:7
4208:6
4204:5
4200:4
4196:3
4188:1
4186:(
4139:)
4129:8
4125:6
4121:5
4117:4
4113:3
4105:1
4103:(
4063:)
4057:4
4053:3
4049:2
4045:1
4043:(
3986:)
3980:2
3976:1
3974:(
3541:e
3534:t
3527:v
3495:4
3490:3
3485:2
3480:1
3290:e
3283:t
3276:v
3126:B
3121:A
3103:U
3098:S
3093:N
3088:B
2789:e
2782:t
2775:v
2713:e
2706:t
2699:v
2686:.
2654:.
2632::
2611:.
2599::
2582:.
2570::
2564:2
2553:.
2533::
2516:.
2496::
2479:.
2467::
2461:2
2450:.
2436::
2415:.
2403::
2386:.
2374::
2357:.
2345::
2327:.
2315::
2297:.
2273::
2265::
2244:.
2232::
2214:.
2193:.
2181::
2164:.
2144::
2127:.
2107::
2090:.
2070::
2053:.
2033::
2027:6
2016:.
1994::
1970:.
1958::
1935:.
1913::
1886:.
1860:.
1836::
1813:.
1793::
1767:.
1753::
1723:.
1699::
1672:.
1650::
1642::
1615:.
1598:.
1586::
1563:.
1545:.
293:)
190:)
173::
20:)
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
