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carrying two embryos. 5 of the surrogates became pregnant. From these five surrogates, three live births proceeded. In these three monkey births, only one infant, ANDi, carried the transgene. Research team leader Gerald
Schatten said the technique that created ANDi would become a vital tool for scientists investigating therapies for human diseases.
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During the method in which ANDi was created, 224 eggs were injected with the protein and only 166 or 75% were successfully fertilized. 126 or 76% of these fertilized eggs developed to the four-cell-stage embryos. 40 of the fertilized embryos were implanted in 20 surrogate rhesus mothers, each
136:. Since ANDi was born, scientists want to introduce more significant DNA changes. Scientists are looking to make genetic modifications such as those that would make primates closely mimic human diseases like breast cancer or
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By being able to genetically modify a monkey, a new breakthrough in technology was formed. ANDi was created in the hope of finding a cure for complicated human diseases such as
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Chan, AWS; et al. (2001). "Transgenic
Monkeys Produced by Retroviral Gene Transfer into Mature Oocytes".
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Although ANDi carries the gene, it does not appear to be functional; ANDi does not actually glow.
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that states a
Knowledge editor's personal feelings or presents an original argument about a topic.
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Dunnett, Stephen (May 2001). "Reverse transcription of inserted DNA in a monkey gives us ANDi".
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91:(OHSU) on October 1, 2001. OHSU named the monkey ANDi because it stands for
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307:"Genetic Engineering Results in First Primate Deliberately Mutated"
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personal reflection, personal essay, or argumentative essay
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107:(GFP). This GFP gene, which is naturally occurring in
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410:Individual primates in the United States
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251:Trends in Pharmacological Sciences
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220:Chiang, Mona (12 February 2001).
89:Oregon Health Sciences University
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327:"Meet ANDi the first GM monkey"
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288:"Glowing future for GM monkey"
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223:"Monkey See, Monkey Glow"
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