260:
237:
134:
159:
266:
165:
3960:
1126:
2590:
42:
1191:. Mutations in either gene have similar clinical presentations. Trifunctional protein deficiency is characterized by decreased activity of long-chain 3-hydroxyacyl-CoA dehydrogenase (LCHAD), long-chain enoyl-CoA hydratase, and long-chain thiolase. This deficiency can be classified into 3 main clinical phenotypes:
1907:"General mitochondrial trifunctional protein (TFP) deficiency as a result of either alpha- or beta-subunit mutations exhibits similar phenotypes because mutations in either subunit alter TFP complex expression and subunit turnover"
1442:"General mitochondrial trifunctional protein (TFP) deficiency as a result of either alpha- or beta-subunit mutations exhibits similar phenotypes because mutations in either subunit alter TFP complex expression and subunit turnover"
1573:
den Boer ME, Dionisi-Vici C, Chakrapani A, van Thuijl AO, Wanders RJ, Wijburg FA (June 2003). "Mitochondrial trifunctional protein deficiency: a severe fatty acid oxidation disorder with cardiac and neurologic involvement".
1360:
Zong NC, Li H, Li H, Lam MP, Jimenez RC, Kim CS, Deng N, Kim AK, Choi JH, Zelaya I, Liem D, Meyer D, Odeberg J, Fang C, Lu HJ, Xu T, Weiss J, Duan H, Uhlen M, Yates JR, Apweiler R, Ge J, Hermjakob H, Ping P (October 2013).
66:, ECHB, MSTP029, MTPB, TP-BETA, hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit, hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta
2543:
Frackowiak J, Mazur-Kolecka B, Kaczmarski W, Dickson D (2001). "Deposition of
Alzheimer's vascular amyloid-beta is associated with decreased expression of brain L-3-hydroxyacyl-coenzyme A dehydrogenase (ERAB)".
1829:"Vectorial proteomics reveal targeting, phosphorylation and specific fragmentation of polymerase I and transcript release factor (PTRF) at the surface of caveolae in human adipocytes"
2453:
Gevaert K, Goethals M, Martens L, et al. (2003). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides".
2753:
1223:, and respiratory failure. The deficiency has presented as hydrops fetalis and HELLP syndrome in fetuses. A compound heterozygous mutation of the HADHB gene can cause axonal
2903:
273:
172:
1481:
Sonta SI, Sandberg AA (1977). "Chromosomes and causation of human cancer and leukemia: XXVIII. Value of detailed chromosome studies on large numbers of cells in CML".
2047:
Zhao Y, Meng XM, Wei YJ, et al. (2003). "Cloning and characterization of a novel cardiac-specific kinase that interacts specifically with cardiac troponin I.".
1410:
2645:
1243:
in animals and humans. Additionally, HADHB has been shown to bind to the distal 3’ untranslated region of renin mRNA, thereby regulating renin protein expression.
2135:
Purevsuren J, Fukao T, Hasegawa Y, et al. (2009). "Clinical and molecular aspects of
Japanese patients with mitochondrial trifunctional protein deficiency".
2328:
Fould B, Garlatti V, Neumann E, et al. (2010). "Structural and functional characterization of the recombinant human mitochondrial trifunctional protein".
3496:
3491:
2018:
Middleton B (1994). "The mitochondrial long-chain trifunctional enzyme: 2-enoyl-CoA hydratase, 3-hydroxyacyl-CoA dehydrogenase and 3-oxoacyl-CoA thiolase".
1227:, which is a neurological disorder, which shows that mutations in this gene can result in deficiencies that present in new forms not currently described.
3297:
2613:
765:
746:
95:
3479:
2412:"Mild trifunctional protein deficiency is associated with progressive neuropathy and myopathy and suggests a novel genotype-phenotype correlation"
1942:"Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes"
3486:
2896:
1320:
2881:
1302:
3982:
3474:
3219:
3646:
3141:
3074:
2838:
2638:
1086:
259:
3614:
3033:
2731:
1346:"Entrez Gene: hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein)"
997:
3679:
3430:
3368:
3260:
3079:
2889:
1004:
236:
3425:
3420:
3069:
1345:
1188:
1872:"HADHB, HuR, and CP1 bind to the distal 3'-untranslated region of human renin mRNA and differentially modulate renin expression"
1762:"HADHB, HuR, and CP1 bind to the distal 3'-untranslated region of human renin mRNA and differentially modulate renin expression"
1171:. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the
3363:
3145:
2796:
1289:
1268:
1105:, with its specific location being 2p23. The gene contains 17 exons. HADHB encodes a 51.2 kDa protein that is composed of 474
3378:
3290:
3061:
2801:
2773:
2746:
2724:
2709:
2674:
2631:
3835:
1285:
158:
133:
3543:
3523:
3437:
1418:
3950:
1264:
1235:
HADHB is a functional molecular target of ERα in the mitochondria, and the interaction may play an important role in the
3464:
3358:
3353:
3162:
2719:
2209:"Molecular and phenotypic heterogeneity in mitochondrial trifunctional protein deficiency due to beta-subunit mutations"
1526:"Molecular and phenotypic heterogeneity in mitochondrial trifunctional protein deficiency due to beta-subunit mutations"
1196:
75:
3626:
3400:
2993:
1224:
2988:
272:
171:
3636:
3469:
3343:
2983:
3820:
1658:
Hong YB, Lee JH, Park JM, Choi YR, Hyun YS, Yoon BR, Yoo JH, Koo H, Jung SC, Chung KW, Choi BO (5 December 2013).
1609:
Jackson S, Kler RS, Bartlett K, Briggs H, Bindoff LA, Pourfarzam M, Gardner-Medwin D, Turnbull DM (October 1992).
265:
164:
3936:
3923:
3910:
3897:
3884:
3871:
3858:
3584:
3560:
3511:
3395:
3348:
3323:
3283:
3242:
3203:
3185:
3017:
3830:
3784:
3727:
3589:
3314:
2823:
2604:
810:
83:
2252:"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)"
3732:
3631:
3538:
3038:
2855:
2833:
2813:
791:
1136:
This gene encodes the beta subunit of the mitochondrial trifunctional protein, a catalyst of mitochondrial
3599:
3594:
3459:
3104:
3052:
2960:
2818:
2714:
1144:. The HADHB protein catalyzes the final step of beta-oxidation, in which 3-ketoacyl CoA is cleaved by the
3753:
3672:
3579:
3574:
2920:
1711:"Estrogen receptor alpha interacts with mitochondrial protein HADHB and affects beta-oxidation activity"
3825:
3641:
3528:
3515:
3415:
2970:
2503:
2370:
2177:
2097:
1102:
147:
62:
3789:
3373:
3180:
3134:
2998:
2975:
2870:
2860:
2828:
976:
972:
951:
947:
917:
913:
888:
884:
2600:
3722:
2865:
2569:
2478:
2238:
2072:
1555:
1506:
107:
2359:"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences"
980:
943:
909:
880:
2594:
1207:. Additionally, some presents showed symptoms associated with myopathy, recurrent and episodic
3987:
3604:
3333:
2955:
2561:
2531:
2470:
2441:
2398:
2345:
2316:
2281:
2230:
2195:
2152:
2123:
2064:
2035:
2006:
1971:
1928:
1893:
1858:
1815:
1783:
1742:
1691:
1640:
1591:
1547:
1498:
1463:
1392:
1114:
55:
1660:"A compound heterozygous mutation in HADHB gene causes an axonal Charcot-Marie-tooth disease"
3768:
3763:
3737:
3665:
3569:
3533:
2916:
2553:
2521:
2511:
2462:
2431:
2423:
2388:
2378:
2337:
2306:
2271:
2263:
2220:
2185:
2144:
2113:
2105:
2056:
2027:
1996:
1961:
1953:
1918:
1883:
1848:
1840:
1773:
1760:
Adams DJ, Beveridge DJ, van der Weyden L, Mangs H, Leedman PJ, Morris BJ (7 November 2003).
1732:
1722:
1681:
1671:
1630:
1622:
1583:
1537:
1490:
1453:
1382:
1374:
1240:
352:
283:
227:
182:
17:
103:
3815:
3799:
3712:
3609:
3310:
3275:
2658:
327:
2507:
2374:
2181:
2101:
3964:
3853:
3794:
3195:
3172:
3089:
2806:
2689:
2666:
2526:
2491:
2118:
2085:
1966:
1941:
1923:
1906:
1853:
1828:
1737:
1710:
1686:
1659:
1458:
1441:
1387:
1362:
1216:
1208:
1137:
1130:
2557:
2436:
2411:
2393:
2358:
2276:
2251:
1635:
1610:
680:
675:
670:
665:
660:
644:
639:
634:
629:
624:
619:
614:
609:
593:
588:
583:
578:
573:
563:
558:
553:
548:
543:
3976:
3758:
3717:
2701:
2684:
2617:
1363:"Integration of cardiac proteome biology and medicine by a specialized knowledgebase"
1220:
1200:
530:
2573:
2492:"Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression"
2482:
2242:
2076:
1559:
1510:
87:
3707:
2924:
1172:
345:
124:
1378:
2623:
2516:
111:
3931:
3866:
3702:
3548:
3306:
2946:
2679:
2148:
1325:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1307:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1125:
1106:
3959:
428:
3234:
3009:
2928:
2912:
2791:
2768:
2060:
1212:
1153:
1149:
1141:
244:
141:
91:
2166:"Generation and annotation of the DNA sequences of human chromosomes 2 and 4"
1676:
3905:
3879:
2295:"Complete sequencing and characterization of 21,243 full-length human cDNAs"
1727:
1440:
Spiekerkoetter U, Khuchua Z, Yue Z, Bennett MJ, Strauss AW (February 2004).
710:
488:
366:
311:
298:
210:
197:
99:
2565:
2535:
2474:
2402:
2383:
2349:
2320:
2285:
2234:
2199:
2156:
2127:
2068:
2010:
2001:
1984:
1975:
1932:
1897:
1888:
1871:
1862:
1819:
1787:
1778:
1761:
1746:
1695:
1595:
1551:
1494:
1467:
1396:
2589:
2445:
2039:
1644:
1044:
1039:
549:
acyltransferase activity, transferring groups other than amino-acyl groups
3338:
3252:
1587:
1502:
1236:
1204:
1192:
1157:
1110:
1090:
1028:
855:
836:
2190:
2165:
2109:
1524:
Spiekerkoetter U, Sun B, Khuchua Z, Bennett MJ, Strauss AW (June 2003).
568:
2267:
2225:
2208:
2031:
1957:
1844:
1542:
1525:
822:
777:
2341:
1626:
3918:
3688:
3619:
3447:
3442:
3383:
3128:
3123:
2931:
2763:
2758:
2654:
1072:
1012:
732:
2427:
2466:
2311:
2294:
1215:. In some cases, symptoms of the deficiency can present as dilated
3892:
3501:
3388:
3150:
3118:
3113:
3108:
2843:
1184:
1145:
1124:
695:
691:
3405:
2741:
2736:
1168:
1079:
79:
3661:
3279:
2885:
2627:
2490:
Hendrickson SL, Lautenberger JA, Chinn LW, et al. (2010).
41:
1870:
Adams DJ, Beveridge DJ, van der Weyden L, et al. (2003).
1611:"Combined enzyme defect of mitochondrial fatty acid oxidation"
1164:
1152:. The thiol is inserted between C-2 and C-3, which yields an
1985:"The layered structure of human mitochondrial DNA nucleoids"
2357:
Strausberg RL, Feingold EA, Grouse LH, et al. (2002).
3657:
2207:
Spiekerkoetter U, Sun B, Khuchua Z, et al. (2003).
1905:
Spiekerkoetter U, Khuchua Z, Yue Z, et al. (2004).
1827:
Aboulaich N, Vainonen JP, StrĂĄlfors P, Vener AV (2004).
335:
2250:
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
1415:
Cardiac
Organellar Protein Atlas Knowledgebase (COPaKB)
2410:
Ibdah JA, Tein I, Dionisi-Vici C, et al. (1998).
2164:
Hillier LW, Graves TA, Fulton RS, et al. (2005).
3948:
1940:
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006).
500:
2754:
Branched-chain alpha-keto acid dehydrogenase complex
2086:"Network organization of the human autophagy system"
1203:, and late-adolescent onset of primarily a skeletal
3844:
3808:
3777:
3746:
3695:
3559:
3510:
3322:
3251:
3232:
3212:
3194:
3171:
3097:
3088:
3060:
3051:
3026:
3007:
2969:
2945:
2938:
2856:
Phosphoenolpyruvate sugar phosphotransferase system
2784:
2700:
2665:
965:
936:
902:
873:
559:
long-chain-3-hydroxyacyl-CoA dehydrogenase activity
471:
dentate gyrus of hippocampal formation granule cell
2293:Ota T, Suzuki Y, Nishikawa T, et al. (2004).
1411:"Trifunctional enzyme subunit beta, mitochondrial"
1281:
1279:
1277:
1260:
1258:
1256:
1195:onset of a severe, lethal condition resulting in
282:
181:
2084:Behrends C, Sowa ME, Gygi SP, Harper JW (2010).
1806:Wang R, Yang Z, Zhu JM, et al. (2006). "".
1183:Mutations in this gene, along with mutations in
1057:Trifunctional enzyme subunit beta, mitochondrial
2675:Photosynthetic reaction center complex proteins
29:Protein-coding gene in the species Homo sapiens
1286:GRCm38: Ensembl release 89: ENSMUSG00000059447
3673:
3291:
2897:
2639:
8:
3497:2-acylglycerol-3-phosphate O-acyltransferase
3492:1-acylglycerol-3-phosphate O-acyltransferase
1983:Bogenhagen DF, Rousseau D, Burke S (2008).
1265:GRCh38: Ensembl release 89: ENSG00000138029
3680:
3666:
3658:
3298:
3284:
3276:
3094:
3057:
2942:
2904:
2890:
2882:
2646:
2632:
2624:
2614:United States National Library of Medicine
706:
526:
401:Skeletal muscle tissue of rectus abdominis
323:
222:
119:
2603:at the U.S. National Library of Medicine
2525:
2515:
2435:
2392:
2382:
2310:
2275:
2224:
2189:
2117:
2000:
1965:
1922:
1887:
1852:
1777:
1736:
1726:
1685:
1675:
1634:
1541:
1457:
1386:
2612:This article incorporates text from the
1340:
1338:
1336:
1334:
1160:molecule, which is two carbons shorter.
579:3-hydroxyacyl-CoA dehydrogenase activity
3955:
1252:
594:long-chain-enoyl-CoA hydratase activity
3487:Glycerol-3-phosphate O-acyltransferase
31:
3480:Lecithin—cholesterol acyltransferase
1615:The Journal of Clinical Investigation
1199:(SIDS), infantile onset of a hepatic
589:acetyl-CoA C-acyltransferase activity
405:cardiac muscle tissue of right atrium
287:
248:
243:
186:
145:
140:
7:
3475:Glyceronephosphate O-acyltransferase
3220:Hydroxyacyl-Coenzyme A dehydrogenase
1167:and decreases the stability of some
3647:Sulfoacetaldehyde acetyltransferase
3339:Acetyl-Coenzyme A acetyltransferase
3075:Carnitine-acylcarnitine translocase
2839:Mitochondrial trifunctional protein
1766:The Journal of Biological Chemistry
1715:Molecular & Cellular Proteomics
1087:mitochondrial trifunctional protein
3563:: converted into alkyl on transfer
3034:Glycerol-3-phosphate dehydrogenase
1924:10.1203/01.PDR.0000103931.80055.06
1709:Zhou Z, Zhou J, Du Y (July 2012).
1459:10.1203/01.pdr.0000103931.80055.06
1163:The encoded protein can also bind
962:
933:
899:
870:
846:
827:
801:
782:
756:
737:
505:
423:
361:
340:
25:
3369:Chloramphenicol acetyltransferase
3261:Long-chain-aldehyde dehydrogenase
3080:Carnitine palmitoyltransferase II
1075:that in humans is encoded by the
676:cardiolipin acyl-chain remodeling
3958:
3421:Carnitine O-palmitoyltransferase
3070:Carnitine palmitoyltransferase I
2588:
1189:trifunctional protein deficiency
271:
264:
258:
235:
170:
163:
157:
132:
40:
3364:Beta-galactoside transacetylase
2797:Carbamoyl phosphate synthase II
1175:in a head-to-head orientation.
1129:Enzymatic activity of HADHB in
3379:Serotonin N-acetyl transferase
3326:: other than amino-acyl groups
2802:Aspartate carbamoyltransferase
2710:Pyruvate dehydrogenase complex
1483:American Journal of Hematology
489:More reference expression data
1:
3544:Keratinocyte transglutaminase
3524:Gamma-glutamyl transpeptidase
3438:Serine C-palmitoyltransferase
2834:Glycine decarboxylase complex
2829:Fatty acid synthetase complex
2558:10.1016/S0006-8993(01)02497-0
1379:10.1161/CIRCRESAHA.113.301151
1148:group of another molecule of
1101:The HADHB gene is located on
256:
155:
3465:Aminolevulinic acid synthase
3359:Acetyl-CoA C-acyltransferase
3354:Dihydrolipoyl transacetylase
3163:Acetyl-CoA C-acyltransferase
2517:10.1371/journal.pone.0012862
2363:Proc. Natl. Acad. Sci. U.S.A
1197:sudden infant death syndrome
666:fatty acid metabolic process
625:mitochondrial inner membrane
615:mitochondrial outer membrane
554:enoyl-CoA hydratase activity
381:myocardium of left ventricle
18:Acetyl-CoA C-acyltransferase
3983:Genes on human chromosome 2
3627:2-hydroxyglutarate synthase
2994:3-Hydroxyacyl ACP dehydrase
2149:10.1016/j.ymgme.2009.07.011
1225:Charcot-Marie-tooth disease
1113:have been observed through
4004:
3637:2-isopropylmalate synthase
3470:Beta-ketoacyl-ACP synthase
3344:N-Acetylglutamate synthase
2984:Beta-ketoacyl-ACP synthase
2866:Sucrase-isomaltase complex
2732:Oxoglutarate dehydrogenase
1808:Zhonghua Fu Chan Ke Za Zhi
1211:, and sensorimotor axonal
1085:HADHB is a subunit of the
1065:acetyl-CoA acyltransferase
3836:Michaelis–Menten kinetics
3585:Decylhomocitrate synthase
3396:Histone acetyltransferase
3349:Choline acetyltransferase
3243:Malonyl-CoA decarboxylase
3204:Propionyl-CoA carboxylase
3186:2,4 Dienoyl-CoA reductase
3018:Stearoyl-CoA desaturase-1
2061:10.1007/s00109-003-0427-x
1576:The Journal of Pediatrics
1321:"Mouse PubMed Reference:"
1303:"Human PubMed Reference:"
1043:
1038:
1034:
1027:
1011:
992:
969:
940:
929:
906:
877:
866:
853:
849:
834:
830:
821:
808:
804:
789:
785:
776:
763:
759:
744:
740:
731:
716:
709:
705:
689:
681:fatty acid beta-oxidation
529:
525:
513:
508:
499:
486:
435:
426:
413:quadriceps femoris muscle
373:
364:
334:
326:
322:
305:
292:
255:
234:
225:
221:
204:
191:
154:
131:
122:
118:
73:
70:
60:
53:
48:
39:
34:
3728:Diffusion-limited enzyme
3590:2-methylcitrate synthase
2989:Î’-Ketoacyl ACP reductase
2824:Electron transport chain
2605:Medical Subject Headings
1677:10.1186/1471-2350-14-125
1059:(TP-beta) also known as
574:acyltransferase activity
389:tibialis anterior muscle
3632:3-propylmalate synthase
3539:Tissue transglutaminase
2814:P450-containing systems
1728:10.1074/mcp.m111.011056
1061:3-ketoacyl-CoA thiolase
1005:Chr 5: 30.36 – 30.39 Mb
998:Chr 2: 26.24 – 26.29 Mb
3600:3-ethylmalate synthase
3595:2-ethylmalate synthase
3460:Acyltransferase like 2
3105:Acyl CoA dehydrogenase
2961:Acetyl-CoA carboxylase
2819:Cytochrome b6f complex
2384:10.1073/pnas.242603899
2002:10.1074/jbc.M708444200
1889:10.1074/jbc.M307782200
1779:10.1074/jbc.m307782200
1495:10.1002/ajh.2830030202
1133:
635:mitochondrial nucleoid
630:mitochondrial envelope
409:triceps brachii muscle
3821:Eadie–Hofstee diagram
3754:Allosteric regulation
3580:Citrate (Re)-synthase
3575:Decylcitrate synthase
3516:Aminoacyltransferases
3416:palmitoyltransferases
2921:fatty acid metabolism
2659:multienzyme complexes
1179:Clinical significance
1128:
640:extracellular exosome
620:endoplasmic reticulum
3831:Lineweaver–Burk plot
3642:Homocitrate synthase
3529:Peptidyl transferase
2971:Fatty acid synthesis
2601:HADHB+protein,+human
2597:at Wikimedia Commons
1664:BMC Medical Genetics
1588:10.1067/mpd.2003.231
1367:Circulation Research
544:transferase activity
397:gastrocnemius muscle
250:Chromosome 5 (mouse)
148:Chromosome 2 (human)
3374:N-acetyltransferase
3181:Enoyl CoA isomerase
3135:Enoyl-CoA hydratase
2999:Enoyl ACP reductase
2976:Fatty acid synthase
2871:Tryptophan synthase
2861:Polyketide synthase
2508:2010PLoSO...512862H
2375:2002PNAS...9916899M
2191:10.1038/nature03466
2182:2005Natur.434..724H
2110:10.1038/nature09204
2102:2010Natur.466...68B
2020:Biochem. Soc. Trans
3790:Enzyme superfamily
3723:Enzyme promiscuity
3334:acetyltransferases
2616:, which is in the
2268:10.1101/gr.2596504
2226:10.1002/humu.10211
2032:10.1042/bst0220427
1958:10.1101/gr.4039406
1845:10.1042/BJ20040647
1721:(7): M111.011056.
1543:10.1002/humu.10211
1446:Pediatric Research
1201:Reye-like syndrome
1134:
811:ENSMUSG00000059447
654:Biological process
603:Cellular component
569:catalytic activity
537:Molecular function
3946:
3945:
3655:
3654:
3605:ATP citrate lyase
3273:
3272:
3269:
3268:
3228:
3227:
3047:
3046:
2956:ATP citrate lyase
2879:
2878:
2593:Media related to
2369:(26): 16899–903.
2342:10.1021/bi100742w
2137:Mol. Genet. Metab
1882:(45): 44894–903.
1772:(45): 44894–903.
1627:10.1172/jci115983
1115:mass spectrometry
1069:beta-ketothiolase
1054:
1053:
1050:
1049:
1023:
1022:
988:
987:
959:
958:
925:
924:
896:
895:
862:
861:
843:
842:
817:
816:
798:
797:
772:
771:
753:
752:
701:
700:
521:
520:
517:
516:
495:
494:
482:
481:
420:
419:
318:
317:
217:
216:
112:HADHB - orthologs
16:(Redirected from
3995:
3963:
3962:
3954:
3826:Hanes–Woolf plot
3769:Enzyme activator
3764:Enzyme inhibitor
3738:Enzyme catalysis
3682:
3675:
3668:
3659:
3615:HMG-CoA synthase
3570:Citrate synthase
3534:Transglutaminase
3311:acyltransferases
3300:
3293:
3286:
3277:
3095:
3058:
3027:Triacyl glycerol
2943:
2917:lipid metabolism
2906:
2899:
2892:
2883:
2648:
2641:
2634:
2625:
2592:
2577:
2539:
2529:
2519:
2486:
2449:
2439:
2406:
2396:
2386:
2353:
2324:
2314:
2289:
2279:
2246:
2228:
2203:
2193:
2176:(7034): 724–31.
2160:
2131:
2121:
2080:
2043:
2014:
2004:
1979:
1969:
1936:
1926:
1901:
1891:
1866:
1856:
1839:(Pt 2): 237–48.
1823:
1792:
1791:
1781:
1757:
1751:
1750:
1740:
1730:
1706:
1700:
1699:
1689:
1679:
1655:
1649:
1648:
1638:
1606:
1600:
1599:
1570:
1564:
1563:
1545:
1521:
1515:
1514:
1478:
1472:
1471:
1461:
1437:
1431:
1430:
1428:
1426:
1417:. Archived from
1407:
1401:
1400:
1390:
1356:
1350:
1349:
1342:
1329:
1328:
1317:
1311:
1310:
1299:
1293:
1283:
1272:
1262:
1241:lipid metabolism
1156:molecule and an
1036:
1035:
1007:
1000:
983:
963:
954:
934:
930:RefSeq (protein)
920:
900:
891:
871:
847:
828:
802:
783:
757:
738:
707:
661:lipid metabolism
527:
506:
491:
463:genital tubercle
431:
429:Top expressed in
424:
369:
367:Top expressed in
362:
341:
324:
314:
301:
290:
275:
268:
262:
251:
239:
223:
213:
200:
189:
174:
167:
161:
150:
136:
120:
114:
65:
58:
44:
32:
21:
4003:
4002:
3998:
3997:
3996:
3994:
3993:
3992:
3973:
3972:
3969:
3957:
3949:
3947:
3942:
3854:Oxidoreductases
3840:
3816:Enzyme kinetics
3804:
3800:List of enzymes
3773:
3742:
3713:Catalytic triad
3691:
3686:
3656:
3651:
3610:Malate synthase
3555:
3506:
3318:
3304:
3274:
3265:
3247:
3224:
3208:
3190:
3167:
3084:
3043:
3022:
3003:
2974:
2965:
2934:
2910:
2880:
2875:
2780:
2696:
2661:
2652:
2585:
2580:
2542:
2489:
2455:Nat. Biotechnol
2452:
2428:10.1172/JCI2091
2416:J. Clin. Invest
2409:
2356:
2336:(39): 8608–17.
2327:
2292:
2262:(10B): 2121–7.
2249:
2206:
2163:
2134:
2096:(7302): 68–76.
2083:
2046:
2017:
1982:
1939:
1904:
1869:
1826:
1805:
1801:
1799:Further reading
1796:
1795:
1759:
1758:
1754:
1708:
1707:
1703:
1657:
1656:
1652:
1608:
1607:
1603:
1572:
1571:
1567:
1523:
1522:
1518:
1480:
1479:
1475:
1439:
1438:
1434:
1424:
1422:
1421:on 4 March 2016
1409:
1408:
1404:
1359:
1357:
1353:
1344:
1343:
1332:
1319:
1318:
1314:
1301:
1300:
1296:
1284:
1275:
1263:
1254:
1249:
1233:
1181:
1123:
1099:
1045:View/Edit Mouse
1040:View/Edit Human
1003:
996:
993:Location (UCSC)
979:
975:
971:
950:
946:
942:
916:
912:
908:
887:
883:
879:
792:ENSG00000138029
685:
649:
598:
564:protein binding
487:
478:
473:
469:
465:
461:
457:
453:
449:
445:
443:muscle of thigh
441:
427:
416:
411:
407:
403:
399:
395:
391:
387:
383:
379:
377:right ventricle
365:
309:
296:
288:
278:
277:
276:
269:
249:
226:Gene location (
208:
195:
187:
177:
176:
175:
168:
146:
123:Gene location (
74:
61:
54:
30:
23:
22:
15:
12:
11:
5:
4001:
3999:
3991:
3990:
3985:
3975:
3974:
3968:
3967:
3944:
3943:
3941:
3940:
3927:
3914:
3901:
3888:
3875:
3862:
3848:
3846:
3842:
3841:
3839:
3838:
3833:
3828:
3823:
3818:
3812:
3810:
3806:
3805:
3803:
3802:
3797:
3792:
3787:
3781:
3779:
3778:Classification
3775:
3774:
3772:
3771:
3766:
3761:
3756:
3750:
3748:
3744:
3743:
3741:
3740:
3735:
3730:
3725:
3720:
3715:
3710:
3705:
3699:
3697:
3693:
3692:
3687:
3685:
3684:
3677:
3670:
3662:
3653:
3652:
3650:
3649:
3644:
3639:
3634:
3629:
3624:
3623:
3622:
3612:
3607:
3602:
3597:
3592:
3587:
3582:
3577:
3572:
3566:
3564:
3557:
3556:
3554:
3553:
3552:
3551:
3546:
3541:
3531:
3526:
3520:
3518:
3508:
3507:
3505:
3504:
3499:
3494:
3489:
3483:
3482:
3477:
3472:
3467:
3462:
3453:
3452:
3451:
3450:
3445:
3435:
3434:
3433:
3428:
3411:
3410:
3409:
3408:
3403:
3393:
3392:
3391:
3386:
3381:
3371:
3366:
3361:
3356:
3351:
3346:
3341:
3329:
3327:
3320:
3319:
3305:
3303:
3302:
3295:
3288:
3280:
3271:
3270:
3267:
3266:
3264:
3263:
3257:
3255:
3249:
3248:
3246:
3245:
3239:
3237:
3230:
3229:
3226:
3225:
3223:
3222:
3216:
3214:
3210:
3209:
3207:
3206:
3200:
3198:
3192:
3191:
3189:
3188:
3183:
3177:
3175:
3169:
3168:
3166:
3165:
3159:
3158:
3153:
3148:
3138:
3137:
3132:
3126:
3121:
3116:
3111:
3101:
3099:
3092:
3090:Beta oxidation
3086:
3085:
3083:
3082:
3077:
3072:
3066:
3064:
3062:Acyl transport
3055:
3049:
3048:
3045:
3044:
3042:
3041:
3036:
3030:
3028:
3024:
3023:
3021:
3020:
3014:
3012:
3005:
3004:
3002:
3001:
2996:
2991:
2986:
2980:
2978:
2967:
2966:
2964:
2963:
2958:
2952:
2950:
2940:
2936:
2935:
2911:
2909:
2908:
2901:
2894:
2886:
2877:
2876:
2874:
2873:
2868:
2863:
2858:
2853:
2852:
2851:
2846:
2836:
2831:
2826:
2821:
2816:
2811:
2810:
2809:
2807:Dihydroorotase
2804:
2799:
2788:
2786:
2782:
2781:
2779:
2778:
2777:
2776:
2771:
2766:
2761:
2751:
2750:
2749:
2744:
2739:
2729:
2728:
2727:
2722:
2717:
2706:
2704:
2698:
2697:
2695:
2694:
2693:
2692:
2687:
2677:
2671:
2669:
2667:Photosynthesis
2663:
2662:
2653:
2651:
2650:
2643:
2636:
2628:
2609:
2608:
2598:
2584:
2583:External links
2581:
2579:
2578:
2552:(1–2): 44–53.
2540:
2487:
2467:10.1038/nbt810
2450:
2407:
2354:
2325:
2312:10.1038/ng1285
2290:
2247:
2219:(6): 598–607.
2204:
2161:
2132:
2081:
2055:(5): 297–304.
2044:
2015:
1995:(6): 3665–75.
1980:
1937:
1902:
1867:
1824:
1802:
1800:
1797:
1794:
1793:
1752:
1701:
1650:
1621:(4): 1219–25.
1601:
1565:
1536:(6): 598–607.
1530:Human Mutation
1516:
1473:
1432:
1402:
1373:(9): 1043–53.
1351:
1330:
1312:
1294:
1273:
1251:
1250:
1248:
1245:
1232:
1229:
1217:cardiomyopathy
1209:rhabdomyolysis
1180:
1177:
1140:of long chain
1138:beta-oxidation
1131:beta-oxidation
1122:
1119:
1098:
1095:
1052:
1051:
1048:
1047:
1042:
1032:
1031:
1025:
1024:
1021:
1020:
1018:
1016:
1009:
1008:
1001:
994:
990:
989:
986:
985:
967:
966:
960:
957:
956:
938:
937:
931:
927:
926:
923:
922:
904:
903:
897:
894:
893:
875:
874:
868:
864:
863:
860:
859:
851:
850:
844:
841:
840:
832:
831:
825:
819:
818:
815:
814:
806:
805:
799:
796:
795:
787:
786:
780:
774:
773:
770:
769:
761:
760:
754:
751:
750:
742:
741:
735:
729:
728:
723:
718:
714:
713:
703:
702:
699:
698:
687:
686:
684:
683:
678:
673:
668:
663:
657:
655:
651:
650:
648:
647:
642:
637:
632:
627:
622:
617:
612:
606:
604:
600:
599:
597:
596:
591:
586:
581:
576:
571:
566:
561:
556:
551:
546:
540:
538:
534:
533:
523:
522:
519:
518:
515:
514:
511:
510:
503:
497:
496:
493:
492:
484:
483:
480:
479:
477:
476:
475:tail of embryo
472:
468:
464:
460:
456:
452:
448:
444:
440:
436:
433:
432:
421:
418:
417:
415:
414:
410:
406:
402:
398:
394:
393:jejunal mucosa
390:
386:
385:deltoid muscle
382:
378:
374:
371:
370:
358:
357:
349:
338:
332:
331:
328:RNA expression
320:
319:
316:
315:
307:
303:
302:
294:
291:
286:
280:
279:
270:
263:
257:
253:
252:
247:
241:
240:
232:
231:
219:
218:
215:
214:
206:
202:
201:
193:
190:
185:
179:
178:
169:
162:
156:
152:
151:
144:
138:
137:
129:
128:
116:
115:
72:
68:
67:
59:
51:
50:
46:
45:
37:
36:
28:
24:
14:
13:
10:
9:
6:
4:
3:
2:
4000:
3989:
3986:
3984:
3981:
3980:
3978:
3971:
3966:
3961:
3956:
3952:
3938:
3934:
3933:
3928:
3925:
3921:
3920:
3915:
3912:
3908:
3907:
3902:
3899:
3895:
3894:
3889:
3886:
3882:
3881:
3876:
3873:
3869:
3868:
3863:
3860:
3856:
3855:
3850:
3849:
3847:
3843:
3837:
3834:
3832:
3829:
3827:
3824:
3822:
3819:
3817:
3814:
3813:
3811:
3807:
3801:
3798:
3796:
3795:Enzyme family
3793:
3791:
3788:
3786:
3783:
3782:
3780:
3776:
3770:
3767:
3765:
3762:
3760:
3759:Cooperativity
3757:
3755:
3752:
3751:
3749:
3745:
3739:
3736:
3734:
3731:
3729:
3726:
3724:
3721:
3719:
3718:Oxyanion hole
3716:
3714:
3711:
3709:
3706:
3704:
3701:
3700:
3698:
3694:
3690:
3683:
3678:
3676:
3671:
3669:
3664:
3663:
3660:
3648:
3645:
3643:
3640:
3638:
3635:
3633:
3630:
3628:
3625:
3621:
3618:
3617:
3616:
3613:
3611:
3608:
3606:
3603:
3601:
3598:
3596:
3593:
3591:
3588:
3586:
3583:
3581:
3578:
3576:
3573:
3571:
3568:
3567:
3565:
3562:
3558:
3550:
3547:
3545:
3542:
3540:
3537:
3536:
3535:
3532:
3530:
3527:
3525:
3522:
3521:
3519:
3517:
3513:
3509:
3503:
3500:
3498:
3495:
3493:
3490:
3488:
3485:
3484:
3481:
3478:
3476:
3473:
3471:
3468:
3466:
3463:
3461:
3458:
3455:
3454:
3449:
3446:
3444:
3441:
3440:
3439:
3436:
3432:
3429:
3427:
3424:
3423:
3422:
3419:
3417:
3413:
3412:
3407:
3404:
3402:
3399:
3398:
3397:
3394:
3390:
3387:
3385:
3382:
3380:
3377:
3376:
3375:
3372:
3370:
3367:
3365:
3362:
3360:
3357:
3355:
3352:
3350:
3347:
3345:
3342:
3340:
3337:
3335:
3331:
3330:
3328:
3325:
3321:
3316:
3312:
3308:
3301:
3296:
3294:
3289:
3287:
3282:
3281:
3278:
3262:
3259:
3258:
3256:
3254:
3250:
3244:
3241:
3240:
3238:
3236:
3231:
3221:
3218:
3217:
3215:
3211:
3205:
3202:
3201:
3199:
3197:
3193:
3187:
3184:
3182:
3179:
3178:
3176:
3174:
3170:
3164:
3161:
3160:
3157:
3154:
3152:
3149:
3147:
3143:
3140:
3139:
3136:
3133:
3130:
3127:
3125:
3122:
3120:
3117:
3115:
3112:
3110:
3106:
3103:
3102:
3100:
3096:
3093:
3091:
3087:
3081:
3078:
3076:
3073:
3071:
3068:
3067:
3065:
3063:
3059:
3056:
3054:
3050:
3040:
3037:
3035:
3032:
3031:
3029:
3025:
3019:
3016:
3015:
3013:
3011:
3006:
3000:
2997:
2995:
2992:
2990:
2987:
2985:
2982:
2981:
2979:
2977:
2972:
2968:
2962:
2959:
2957:
2954:
2953:
2951:
2948:
2944:
2941:
2937:
2933:
2930:
2926:
2922:
2918:
2914:
2907:
2902:
2900:
2895:
2893:
2888:
2887:
2884:
2872:
2869:
2867:
2864:
2862:
2859:
2857:
2854:
2850:
2847:
2845:
2842:
2841:
2840:
2837:
2835:
2832:
2830:
2827:
2825:
2822:
2820:
2817:
2815:
2812:
2808:
2805:
2803:
2800:
2798:
2795:
2794:
2793:
2790:
2789:
2787:
2783:
2775:
2772:
2770:
2767:
2765:
2762:
2760:
2757:
2756:
2755:
2752:
2748:
2745:
2743:
2740:
2738:
2735:
2734:
2733:
2730:
2726:
2723:
2721:
2718:
2716:
2713:
2712:
2711:
2708:
2707:
2705:
2703:
2702:Dehydrogenase
2699:
2691:
2688:
2686:
2683:
2682:
2681:
2678:
2676:
2673:
2672:
2670:
2668:
2664:
2660:
2656:
2649:
2644:
2642:
2637:
2635:
2630:
2629:
2626:
2622:
2621:
2619:
2618:public domain
2615:
2606:
2602:
2599:
2596:
2591:
2587:
2586:
2582:
2575:
2571:
2567:
2563:
2559:
2555:
2551:
2547:
2541:
2537:
2533:
2528:
2523:
2518:
2513:
2509:
2505:
2502:(9): e12862.
2501:
2497:
2493:
2488:
2484:
2480:
2476:
2472:
2468:
2464:
2460:
2456:
2451:
2447:
2443:
2438:
2433:
2429:
2425:
2422:(6): 1193–9.
2421:
2417:
2413:
2408:
2404:
2400:
2395:
2390:
2385:
2380:
2376:
2372:
2368:
2364:
2360:
2355:
2351:
2347:
2343:
2339:
2335:
2331:
2326:
2322:
2318:
2313:
2308:
2304:
2300:
2296:
2291:
2287:
2283:
2278:
2273:
2269:
2265:
2261:
2257:
2253:
2248:
2244:
2240:
2236:
2232:
2227:
2222:
2218:
2214:
2210:
2205:
2201:
2197:
2192:
2187:
2183:
2179:
2175:
2171:
2167:
2162:
2158:
2154:
2150:
2146:
2142:
2138:
2133:
2129:
2125:
2120:
2115:
2111:
2107:
2103:
2099:
2095:
2091:
2087:
2082:
2078:
2074:
2070:
2066:
2062:
2058:
2054:
2050:
2045:
2041:
2037:
2033:
2029:
2026:(2): 427–31.
2025:
2021:
2016:
2012:
2008:
2003:
1998:
1994:
1990:
1989:J. Biol. Chem
1986:
1981:
1977:
1973:
1968:
1963:
1959:
1955:
1951:
1947:
1943:
1938:
1934:
1930:
1925:
1920:
1916:
1912:
1908:
1903:
1899:
1895:
1890:
1885:
1881:
1877:
1876:J. Biol. Chem
1873:
1868:
1864:
1860:
1855:
1850:
1846:
1842:
1838:
1834:
1830:
1825:
1821:
1817:
1814:(10): 672–5.
1813:
1809:
1804:
1803:
1798:
1789:
1785:
1780:
1775:
1771:
1767:
1763:
1756:
1753:
1748:
1744:
1739:
1734:
1729:
1724:
1720:
1716:
1712:
1705:
1702:
1697:
1693:
1688:
1683:
1678:
1673:
1669:
1665:
1661:
1654:
1651:
1646:
1642:
1637:
1632:
1628:
1624:
1620:
1616:
1612:
1605:
1602:
1597:
1593:
1589:
1585:
1581:
1577:
1569:
1566:
1561:
1557:
1553:
1549:
1544:
1539:
1535:
1531:
1527:
1520:
1517:
1512:
1508:
1504:
1500:
1496:
1492:
1488:
1484:
1477:
1474:
1469:
1465:
1460:
1455:
1451:
1447:
1443:
1436:
1433:
1420:
1416:
1412:
1406:
1403:
1398:
1394:
1389:
1384:
1380:
1376:
1372:
1368:
1364:
1355:
1352:
1347:
1341:
1339:
1337:
1335:
1331:
1326:
1322:
1316:
1313:
1308:
1304:
1298:
1295:
1291:
1287:
1282:
1280:
1278:
1274:
1270:
1266:
1261:
1259:
1257:
1253:
1246:
1244:
1242:
1238:
1230:
1228:
1226:
1222:
1221:heart failure
1219:, congestive
1218:
1214:
1210:
1206:
1202:
1198:
1194:
1190:
1186:
1178:
1176:
1174:
1170:
1166:
1161:
1159:
1155:
1151:
1147:
1143:
1139:
1132:
1127:
1120:
1118:
1116:
1112:
1108:
1104:
1096:
1094:
1092:
1088:
1083:
1081:
1078:
1074:
1070:
1066:
1062:
1058:
1046:
1041:
1037:
1033:
1030:
1026:
1019:
1017:
1014:
1010:
1006:
1002:
999:
995:
991:
984:
982:
978:
974:
968:
964:
961:
955:
953:
949:
945:
939:
935:
932:
928:
921:
919:
915:
911:
905:
901:
898:
892:
890:
886:
882:
876:
872:
869:
867:RefSeq (mRNA)
865:
858:
857:
852:
848:
845:
839:
838:
833:
829:
826:
824:
820:
813:
812:
807:
803:
800:
794:
793:
788:
784:
781:
779:
775:
768:
767:
762:
758:
755:
749:
748:
743:
739:
736:
734:
730:
727:
724:
722:
719:
715:
712:
708:
704:
697:
693:
688:
682:
679:
677:
674:
672:
669:
667:
664:
662:
659:
658:
656:
653:
652:
646:
645:mitochondrion
643:
641:
638:
636:
633:
631:
628:
626:
623:
621:
618:
616:
613:
611:
608:
607:
605:
602:
601:
595:
592:
590:
587:
585:
582:
580:
577:
575:
572:
570:
567:
565:
562:
560:
557:
555:
552:
550:
547:
545:
542:
541:
539:
536:
535:
532:
531:Gene ontology
528:
524:
512:
507:
504:
502:
498:
490:
485:
474:
470:
466:
462:
458:
454:
450:
446:
442:
438:
437:
434:
430:
425:
422:
412:
408:
404:
400:
396:
392:
388:
384:
380:
376:
375:
372:
368:
363:
360:
359:
356:
354:
350:
348:
347:
343:
342:
339:
337:
333:
329:
325:
321:
313:
308:
304:
300:
295:
285:
281:
274:
267:
261:
254:
246:
242:
238:
233:
229:
224:
220:
212:
207:
203:
199:
194:
184:
180:
173:
166:
160:
153:
149:
143:
139:
135:
130:
126:
121:
117:
113:
109:
105:
101:
97:
93:
89:
85:
81:
77:
69:
64:
57:
52:
47:
43:
38:
33:
27:
19:
3970:
3932:Translocases
3929:
3916:
3903:
3890:
3877:
3867:Transferases
3864:
3851:
3708:Binding site
3456:
3414:
3332:
3307:Transferases
3155:
2925:triglyceride
2848:
2611:
2610:
2549:
2545:
2499:
2495:
2461:(5): 566–9.
2458:
2454:
2419:
2415:
2366:
2362:
2333:
2330:Biochemistry
2329:
2302:
2298:
2259:
2255:
2216:
2212:
2173:
2169:
2143:(4): 372–7.
2140:
2136:
2093:
2089:
2052:
2048:
2023:
2019:
1992:
1988:
1952:(1): 55–65.
1949:
1945:
1917:(2): 190–6.
1914:
1911:Pediatr. Res
1910:
1879:
1875:
1836:
1832:
1811:
1807:
1769:
1765:
1755:
1718:
1714:
1704:
1667:
1663:
1653:
1618:
1614:
1604:
1582:(6): 684–9.
1579:
1575:
1568:
1533:
1529:
1519:
1489:(2): 121–6.
1486:
1482:
1476:
1452:(2): 190–6.
1449:
1445:
1435:
1423:. Retrieved
1419:the original
1414:
1405:
1370:
1366:
1354:
1324:
1315:
1306:
1297:
1234:
1231:Interactions
1187:, result in
1182:
1173:human genome
1162:
1135:
1103:chromosome 2
1100:
1084:
1076:
1068:
1064:
1060:
1056:
1055:
977:NP_001276728
973:NP_001276727
970:
952:NP_001268442
948:NP_001268441
941:
918:NM_001289799
914:NM_001289798
907:
889:NM_001281513
885:NM_001281512
878:
854:
835:
809:
790:
764:
745:
725:
720:
451:right kidney
439:spermatocyte
351:
344:
71:External IDs
26:
3703:Active site
3549:Factor XIII
3173:Unsaturated
3053:Degradation
3010:desaturases
3008:Fatty acid
2947:Malonyl-CoA
2680:Photosystem
2305:(1): 40–5.
2049:J. Mol. Med
1142:fatty acids
1107:amino acids
584:RNA binding
310:30,389,591
297:30,360,246
289:5|5 B1
209:26,290,465
196:26,243,170
49:Identifiers
3977:Categories
3906:Isomerases
3880:Hydrolases
3747:Regulation
3235:acetyl-CoA
3039:Thiokinase
2929:fatty acid
2913:Metabolism
2299:Nat. Genet
2256:Genome Res
2213:Hum. Mutat
1946:Genome Res
1833:Biochem. J
1292:, May 2017
1271:, May 2017
1247:References
1239:-mediated
1213:neuropathy
1154:acetyl CoA
1150:Coenzyme A
1093:activity.
671:metabolism
355:(ortholog)
92:HomoloGene
3785:EC number
3253:Aldehydes
3196:Odd chain
2949:synthesis
2939:Synthesis
2546:Brain Res
1097:Structure
981:NP_663533
944:NP_000174
910:NM_145558
881:NM_000183
711:Orthologs
455:spermatid
447:esophagus
100:GeneCards
3988:EC 2.3.1
3809:Kinetics
3733:Cofactor
3696:Activity
3401:P300/CBP
2574:22800813
2566:11430884
2536:20877624
2496:PLOS ONE
2483:23783563
2475:12665801
2403:12477932
2350:20825197
2321:14702039
2286:15489334
2243:85671653
2235:12754706
2200:15815621
2157:19699128
2128:20562859
2077:13468188
2069:12721663
2011:18063578
1976:16344560
1933:14630990
1898:12933794
1863:15242332
1820:17199921
1788:12933794
1747:22375075
1696:24314034
1596:12838198
1560:85671653
1552:12754706
1511:13141165
1468:14630990
1425:23 March
1397:23965338
1288:–
1267:–
1237:estrogen
1205:myopathy
1193:neonatal
1158:acyl CoA
1121:Function
1111:peptides
1091:thiolase
1089:and has
1029:Wikidata
690:Sources:
610:membrane
467:yolk sac
3965:Biology
3919:Ligases
3689:Enzymes
3098:General
2932:enzymes
2655:Enzymes
2527:2943476
2504:Bibcode
2446:9739053
2371:Bibcode
2178:Bibcode
2119:2901998
2098:Bibcode
2040:7958339
1967:1356129
1854:1134064
1738:3394935
1687:4029087
1670:: 125.
1645:1401059
1388:4076475
1290:Ensembl
1269:Ensembl
823:UniProt
778:Ensembl
717:Species
696:QuickGO
330:pattern
88:2136381
56:Aliases
3951:Portal
3893:Lyases
3620:HMGCS2
3457:other:
3448:SPTLC2
3443:SPTLC1
3384:HGSNAT
3129:ACADSB
3124:ACADVL
2764:BCKDHB
2759:BCKDHA
2607:(MeSH)
2572:
2564:
2534:
2524:
2481:
2473:
2444:
2437:509102
2434:
2401:
2394:139241
2391:
2348:
2319:
2284:
2277:528928
2274:
2241:
2233:
2198:
2170:Nature
2155:
2126:
2116:
2090:Nature
2075:
2067:
2038:
2009:
1974:
1964:
1931:
1896:
1861:
1851:
1818:
1786:
1745:
1735:
1694:
1684:
1643:
1636:443162
1633:
1594:
1558:
1550:
1509:
1503:272120
1501:
1466:
1395:
1385:
1117:data.
1109:; 124
1073:enzyme
1071:is an
1015:search
1013:PubMed
856:Q99JY0
837:P55084
766:231086
733:Entrez
501:BioGPS
188:2p23.3
80:143450
3845:Types
3561:2.3.3
3512:2.3.2
3502:ABHD5
3389:ARD1A
3324:2.3.1
3213:Other
3156:HADHB
3151:HADHA
3119:ACADS
3114:ACADM
3109:ACADL
2849:HADHB
2844:HADHA
2785:Other
2595:HADHB
2570:S2CID
2479:S2CID
2239:S2CID
2073:S2CID
1556:S2CID
1507:S2CID
1185:HADHA
1169:mRNAs
1146:thiol
1077:HADHB
1067:, or
726:Mouse
721:Human
692:Amigo
353:Mouse
346:Human
293:Start
228:Mouse
192:Start
125:Human
104:HADHB
63:HADHB
35:HADHB
3937:list
3930:EC7
3924:list
3917:EC6
3911:list
3904:EC5
3898:list
3891:EC4
3885:list
3878:EC3
3872:list
3865:EC2
3859:list
3852:EC1
3431:CPT2
3426:CPT1
3406:NAT2
3317:2.3)
3146:HADH
2927:and
2742:DLST
2737:OGDH
2562:PMID
2532:PMID
2471:PMID
2442:PMID
2399:PMID
2346:PMID
2317:PMID
2282:PMID
2231:PMID
2196:PMID
2153:PMID
2124:PMID
2065:PMID
2036:PMID
2007:PMID
1972:PMID
1929:PMID
1894:PMID
1859:PMID
1816:PMID
1784:PMID
1743:PMID
1692:PMID
1641:PMID
1592:PMID
1548:PMID
1499:PMID
1464:PMID
1427:2015
1393:PMID
1080:gene
747:3032
336:Bgee
284:Band
245:Chr.
183:Band
142:Chr.
76:OMIM
3233:To
3142:MTP
2792:CAD
2774:DLD
2769:DBT
2747:DLD
2554:doi
2550:907
2522:PMC
2512:doi
2463:doi
2432:PMC
2424:doi
2420:102
2389:PMC
2379:doi
2338:doi
2307:doi
2272:PMC
2264:doi
2221:doi
2186:doi
2174:434
2145:doi
2114:PMC
2106:doi
2094:466
2057:doi
2028:doi
1997:doi
1993:283
1962:PMC
1954:doi
1919:doi
1884:doi
1880:278
1849:PMC
1841:doi
1837:383
1774:doi
1770:278
1733:PMC
1723:doi
1682:PMC
1672:doi
1631:PMC
1623:doi
1584:doi
1580:142
1538:doi
1491:doi
1454:doi
1383:PMC
1375:doi
1371:113
1165:RNA
509:n/a
459:lip
306:End
205:End
108:OMA
96:153
84:MGI
3979::
3514::
3315:EC
3309::
3144::
2923:,
2919:/
2915::
2725:E3
2720:E2
2715:E1
2690:II
2657::
2568:.
2560:.
2548:.
2530:.
2520:.
2510:.
2498:.
2494:.
2477:.
2469:.
2459:21
2457:.
2440:.
2430:.
2418:.
2414:.
2397:.
2387:.
2377:.
2367:99
2365:.
2361:.
2344:.
2334:49
2332:.
2315:.
2303:36
2301:.
2297:.
2280:.
2270:.
2260:14
2258:.
2254:.
2237:.
2229:.
2217:21
2215:.
2211:.
2194:.
2184:.
2172:.
2168:.
2151:.
2141:98
2139:.
2122:.
2112:.
2104:.
2092:.
2088:.
2071:.
2063:.
2053:81
2051:.
2034:.
2024:22
2022:.
2005:.
1991:.
1987:.
1970:.
1960:.
1950:16
1948:.
1944:.
1927:.
1915:55
1913:.
1909:.
1892:.
1878:.
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1857:.
1847:.
1835:.
1831:.
1812:41
1810:.
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1741:.
1731:.
1719:11
1717:.
1713:.
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1666:.
1662:.
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1629:.
1619:90
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1462:.
1450:55
1448:.
1444:.
1413:.
1391:.
1381:.
1369:.
1365:.
1333:^
1323:.
1305:.
1276:^
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694:/
312:bp
299:bp
211:bp
198:bp
106:;
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98:;
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90:;
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1358:]
1348:.
1327:.
1309:.
230:)
127:)
110::
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