44:
204:
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492:, indicating that an understanding of charcoal's ability to adsorb undesirable chemicals was present by this time. Activated charcoal in its current form was developed during the 18th century, first being used during the sugar refining process to remove coloured impurities from raw sugar. Medical use of activated charcoal commenced in the early 19th century; an often-cited experiment demonstrating its properties was carried out in 1835, where a dosage of
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Activated charcoal is biologically inert. When in the presence of some poisons, activated charcoal adsorbs the chemical onto its surface, rendering it unable to interact with the body. This is possible due to its high surface area compared to its volume.
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Although activated charcoal is the most commonly used agent for GI decontamination in poisoned patients, medical professionals use discretion when determining whether or not its use is indicated. In a study of acute poisonings from agricultural
43:
1074:
1301:
1286:
69:
843:
905:
Gogel HK, Tandberg D, Strickland RG (September 1989). "Substances that interfere with guaiac card tests: implications for gastric aspirate testing".
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1082:
1291:
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Elliott CG, Colby TV, Kelly TM, Hicks HG (September 1989). "Charcoal lung. Bronchiolitis obliterans after aspiration of activated charcoal".
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227:. To be effective it must be used within a short time of the poisoning occurring, typically an hour. It does not work for poisonings by
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407:. It can interfere with the absorption of some medications, and lead to unreliable readings in medical tests such as the
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Brooks JK, Bashirelahi N, Reynolds MA (September 2017). "Charcoal and charcoal-based dentifrices: A literature review".
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card test. Activated carbon is also used for bowel preparation by reducing intestinal gas content before abdominal
20:
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has been used since ancient times for poisonings, activated charcoal has been used since the 1900s. It is on the
459:
which can sometimes be fatal if immediate medical treatment is not initiated. The use of activated carbon is
87:
199:
752:
Eddleston M, Juszczak E, Buckley NA, Senarathna L, Mohamed F, Dissanayake W, et al. (February 2008).
256:
942:"Effect of adding a capsule with activated charcoal to abdominal ultrasound preparation on image quality"
388:
631:
Activated Carbon for Water and
Wastewater Treatment: Integration of Adsorption and Biological Treatment
403:. There is some evidence of its effectiveness to prevent diarrhea in cancer patients who have received
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275:
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used charcoal to improve the taste of water stored on ships by containing the water in charred
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754:"Multiple-dose activated charcoal in acute self-poisoning: a randomised controlled trial"
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Claims that activated charcoal will do things such as whiten teeth, cure alcohol-induced
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Michael M, Brittain M, Nagai J, Feld R, Hedley D, Oza A, et al. (November 2004).
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mixed with activated charcoal resulted in no symptoms of poisoning being observed.
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in 1500 BC, where it was used to neutralise bad odours from wounds. By 400 BC, the
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326:. It is not effective for a number of poisonings including: strong acids or bases,
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35:
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were sold in
England starting in the early 19th century, originally as remedy to
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1026:
1075:"Activated charcoal doesn't detox the body – four reasons you should avoid it"
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404:
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866:"Phase II study of activated charcoal to prevent irinotecan-induced diarrhea"
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seeds, the administration of activated carbon did not affect survival rates.
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The Food
Encyclopedia: Over 8,000 Ingredients, Tools, Techniques and People
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World Health
Organization model list of essential medicines: 21st list 2019
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when the ingested substance is an acid, an alkali, or a petroleum product.
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Activated charcoal is used to treat many types of oral poisonings such as
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Warts and all: straight talking advice on life's embarrassing problems
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220:
1165:"Charcoal is one of the most important substances ever discovered"
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279:
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The use of charcoal as a medicinal product can be traced back to
416:
1140:"Charcoal, Activated (Oral Route) Description and Brand Names"
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Jabar AA, Abbas I, Mishah N, Wazan M, Tomehy M (2020-03-31).
165:
602:
706:. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
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Incorrect application (e.g. into the lungs) results in
439:, and prevent bloating, are not supported by evidence.
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1244:
531:. The American Society of Health-System Pharmacists.
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of activated carbon are used in many countries as an
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are less common but serious adverse effects. Use in
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952:(80). Medical Communications Sp. z.o.o.: e12–e17.
727:The American Society of Health-System Pharmacists
562:(2009). Stuart MC, Kouimtzi M, Hill SR (eds.).
290:is generally safe. Activated charcoal works by
112:
1190:"Activated charcoal--past, present and future"
604:. Jones & Bartlett Learning. p. 469.
427:has also been marketed as a pet care product.
1302:World Health Organization essential medicines
1049:"Can activated charcoal help with hangovers?"
8:
34:
16:Medication used to treat ingested poisonings
1287:Chemical substances for emergency medicine
1015:Journal of the American Dental Association
907:The American Journal of Emergency Medicine
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566:. World Health Organization. p. 57.
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251:. It may be taken by mouth or given by a
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1188:Derlet RW, Albertson TE (October 1986).
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505:
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832:. London: Murdoch Books. p. 333.
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715:
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443:also lack evidence and are considered
193:
33:
990:"Charcoal Biscuit Cobs for Dogs 400g"
696:. Geneva: World Health Organization.
535:from the original on 21 December 2016
366:Gastrointestinal tract-related issues
78:
7:
1240:. U.S. National Library of Medicine.
278:. Gastrointestinal obstruction and
48:Activated charcoal for medical use
19:For the pseudoscientific use, see
14:
1254:
733:from the original on 22 May 2014
678:from the original on 2016-12-20.
647:from the original on 2016-12-20.
219:, is a medication used to treat
1194:The Western Journal of Medicine
846:from the original on 2017-09-10
625:Cecen F, Aktas Ö (2011-09-19).
1169:Office for Science and Society
270:. A more serious side effect,
266:, black stools, diarrhea, and
1:
770:10.1016/S0140-6736(08)60270-6
1292:Emergency medical procedures
919:10.1016/0735-6757(89)90248-9
870:Journal of Clinical Oncology
805:. Robert Rose. p. 148.
262:Common side effects include
255:. Other uses include inside
441:Activated charcoal cleanses
1318:
1027:10.1016/j.adaj.2017.05.001
946:Journal of Ultrasonography
94:by mouth, nasogastric tube
25:
21:Activated charcoal cleanse
18:
1073:Medlin S (12 June 2018).
690:World Health Organization
664:. Elsevier. p. 640.
633:. John Wiley & Sons.
560:World Health Organization
41:
564:WHO Model Formulary 2008
276:aspirated into the lungs
883:10.1200/JCO.2004.11.125
661:Novel Carbon Adsorbents
1118:10.1378/chest.96.3.672
958:10.15557/jou.2020.0003
257:hemoperfusion machines
723:"Charcoal, Activated"
529:"Charcoal, Activated"
389:over-the-counter drug
377:and stomach trouble.
1234:"Activated charcoal"
457:pulmonary aspiration
801:Rolland JL (2006).
600:Hamilton R (2015).
467:Mechanism of action
419:and pancreatic and
38:
658:Tascón JM (2012).
213:Activated charcoal
36:Activated charcoal
876:(21): 4410–4417.
839:978-1-921259-84-5
826:Stearn M (2007).
764:(9612): 579–587.
371:Charcoal biscuits
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161:CompTox Dashboard
64:CharcoAid, others
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314:Poison ingestion
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233:corrosive agents
217:activated carbon
215:, also known as
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1148:. Retrieved
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1083:the original
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451:Side effects
434:
423:. A type of
421:renal stones
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309:Medical uses
296:
268:constipation
261:
212:
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31:
1144:Mayo Clinic
1089:26 November
573:10665/44053
486:Phoenicians
413:radiography
397:indigestion
294:the toxin.
272:pneumonitis
200:100.036.697
99:Identifiers
60:Trade names
1297:Toxicology
1271:Categories
1174:2023-08-02
1150:2024-07-03
999:2024-07-03
850:2009-05-03
539:8 December
500:References
494:strychnine
405:irinotecan
401:flatulence
375:flatulence
356:pesticides
221:poisonings
150:2P3VWU3H10
125:ChemSpider
105:CAS Number
437:hangovers
391:to treat
292:adsorbing
284:pregnancy
249:malathion
114:7440-44-0
88:Routes of
80:Monograph
74:Drugs.com
1282:Charcoal
1261:Medicine
1058:13 March
1035:28599961
976:32320165
892:15514383
844:Archived
788:18280328
737:23 April
731:Archived
692:(2019).
676:Archived
645:Archived
533:Archived
393:diarrhea
385:capsules
340:methanol
299:charcoal
264:vomiting
245:alcohols
225:by mouth
1238:PubChem
1216:3538661
1207:1306980
1126:2766830
967:7266072
927:2787993
779:2430417
490:barrels
476:History
381:Tablets
344:ethanol
336:arsenic
332:lithium
241:lithium
229:cyanide
1277:Carbon
1247:Portal
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758:Lancet
668:
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409:guaiac
399:, and
297:While
1106:Chest
1053:WebMD
482:Egypt
431:Other
280:ileus
247:, or
1212:PMID
1122:PMID
1091:2019
1060:2019
1031:PMID
972:PMID
923:PMID
888:PMID
834:ISBN
807:ISBN
784:PMID
739:2014
666:ISBN
635:ISBN
606:ISBN
578:ISBN
541:2016
417:bile
358:and
328:iron
322:and
286:and
237:iron
141:UNII
132:none
70:AHFS
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1114:doi
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766:doi
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383:or
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