753:
877:, couples the transport of the two molecules. The depression in ADP/ATP translocase alternatively faces the matrix and the cytoplasmic sides of the membrane. ADP in the intermembrane space, coming from the cytoplasm, binds the translocase and induces its eversion, resulting in the release of ADP into the matrix. Binding of ATP from the matrix induces eversion and results in the release of ATP into the intermembrane space, subsequently diffusing to the cytoplasm, and concomitantly brings the translocase back to its original conformation. ATP and ADP are the only natural
772:
854:, in a 1:1 ratio. Transport is fully reversible, and its directionality is governed by the concentrations of its substrates (ADP and ATP inside and outside mitochondria), the chelators of the adenine nucleotides, and the mitochondrial membrane potential. The relationship of these parameters can be expressed by an equation solving for the 'reversal potential of the ANT" (Erev_ANT), a value of the mitochondrial membrane potential at which no net transport of adenine nucleotides takes place by the ANT. The ANT and the
31:
984:
975:. Thus, any modification of ADP/ATP translocase mtDNA can lead to a dysfunctional transporter, particularly residues involved in the binding pocket which will compromise translocase efficacy. MM is commonly associated with dysfunctional ADP/ATP translocase, but MM can be induced through many different mitochondrial abnormalities.
864:
ANT is an important modulatory and possible structural component of the
Mitochondrial Permeability Transition Pore, a channel involved in various pathologies whose function still remains elusive. Karch et al. propose a "multi-pore model" in which ANT is at least one of the molecular components of the
787:
ANT has long been thought to function as a homodimer, but this concept was challenged by the projection structure of the yeast Aac3p solved by electron crystallography, which showed that the protein was three-fold symmetric and monomeric, with the translocation pathway for the substrate through the
1030:
nucleotides were distributed in cells in two pools located in the mitochondrial and cytosolic compartments. Shortly thereafter, Pressman hypothesized that the two pools could exchange nucleotides. However, the existence of an ADP/ATP transporter was not postulated until 1964 when Bruni
959:(adPEO) is a common disorder associated with dysfunctional ADP/ATP translocase and can induce paralysis of muscles responsible for eye movements. General symptoms are not limited to the eyes and can include exercise intolerance, muscle weakness, hearing deficit, and more. adPEO shows
830:
of ATP into ADP, ADP is transported back into the mitochondrial matrix, where it can be rephosphorylated to ATP. Because a human typically exchanges the equivalent of their own mass of ATP on a daily basis, ADP/ATP translocase is an important transporter protein with major
1003:(BA) and isobongkrekic acid (isoBA), binds the translocase from the matrix, locking it in a matrix side open conformation. The negatively charged groups of the inhibitors bind strongly to the positively charged residues deep within the binding pocket. The high affinity (
788:
centre. The atomic structure of the bovine ANT confirmed this notion, and provided the first structural fold of a mitochondrial carrier. Further work has demonstrated that ANT is a monomer in detergents and functions as a monomer in mitochondrial membranes.
1060:
in the coding sequences between human and yeast ADP/ATP translocase was 47% while bovine and human sequences extended remarkable to 266 out of 297 residues, or 89.6%. In both cases, the most conserved residues lie in the ADP/ATP substrate binding pocket.
756:
A side view of the translocase spanning the inner mitochondrial membrane. The six α-helices are denoted by different colors. The binding pocket is currently open to the cytoplasmic side and will bind to ADP, transporting it into the matrix. (From
1463:
926:
The translocator cycles between two states, called the cytoplasmic and matrix state, opening up to these compartments in an alternating way. There are structures available that show the translocator locked in a cytoplasmic state by the inhibitor
1010:
in the nanomolar range) makes each inhibitor a deadly poison by obstructing cellular respiration/energy transfer to the rest of the cell. There are structures available that show the translocator locked in a cytoplasmic state by the inhibitor
946:
are associated with dysfunctional human ADP/ATP translocase. Mitochondrial myopathies (MM) refer to a group of clinically and biochemically heterogeneous disorders that share common features of major mitochondrial structural abnormalities in
2414:
Saks VA, Lipina NV, Smirnov VN, Chazov EI (March 1976). "Studies of energy transport in heart cells. The functional coupling between mitochondrial creatine phosphokinase and ATP ADP translocase: kinetic evidence".
1318:
Brandolin G, Dupont Y, Vignais PV (April 1985). "Substrate-induced modifications of the intrinsic fluorescence of the isolated adenine nucleotide carrier protein: demonstration of distinct conformational states".
1952:
Karch J, Bround MJ, Khalil H, et al. Inhibition of mitochondrial permeability transition by deletion of the ANT family and CypD. Sci Adv. 2019;5(8):eaaw4597. Published 2019 Aug 28. doi:10.1126/sciadv.aaw4597
2168:
Kaukonen J, Juselius JK, Tiranti V, Kyttälä A, Zeviani M, Comi GP, Keränen S, Peltonen L, Suomalainen A (August 2000). "Role of adenine nucleotide translocator 1 in mtDNA maintenance".
1660:
Nelson DR, Lawson JE, Klingenberg M, Douglas MG (April 1993). "Site-directed mutagenesis of the yeast mitochondrial ADP/ATP translocator. Six arginines and one lysine are essential".
1411:
Pebay-Peyroula E, Dahout-Gonzalez C, Kahn R, Trézéguet V, Lauquin GJ, Brandolin G (November 2003). "Structure of mitochondrial ADP/ATP carrier in complex with carboxyatractyloside".
791:
ADP/ATP translocase 1 is the major AAC in human cells and the archetypal protein of this family. It has a mass of approximately 30 kDa, consisting of 297 residues. It forms six
822:
ADP/ATP translocase transports ATP synthesized from oxidative phosphorylation into the cytoplasm, where it can be used as the principal energy currency of the cell to power
999:(CATR), binds to the ADP/ATP translocase from the cytoplasmic side, locking it in a cytoplasmic side open conformation. In contrast, the second family, which includes
156:
1896:
Doczi J, Torocsik B, Echaniz-Laguna A, Mousson de
Camaret B, Starkov A, Starkova N, Gál A, Molnár MJ, Kawamata H, Manfredi G, Adam-Vizi V, Chinopoulos C (May 2016).
2589:
951:. The major morphological hallmark of MM is ragged, red fibers containing peripheral and intermyofibrillar accumulations of abnormal mitochondria. In particular,
112:
100:
511:
364:
219:
5610:
1042:
Soon after, an overwhelming amount of research was done in proving the existence and elucidating the link between ADP/ATP translocase and energy transport.
3969:
5010:
1698:
Chinopoulos C, Gerencser AA, Mandi M, Mathe K, Töröcsik B, Doczi J, Turiak L, Kiss G, Konràd C, Vajda S, Vereczki V, Oh RJ, Adam-Vizi V (July 2010).
873:
Under normal conditions, ATP and ADP cannot cross the inner mitochondrial membrane due to their high negative charges, but ADP/ATP translocase, an
1145:
Kunji ER, Aleksandrova A, King MS, Majd H, Ashton VL, Cerson E, Springett R, Kibalchenko M, Tavoulari S, Crichton PG, Ruprecht JJ (October 2016).
806:, mostly consists of basic residues that allow for strong binding to ATP or ADP and has a maximal diameter of 20 Å and a depth of 30 Å. Indeed,
681:, thus providing the cell with its main energy currency. ADP/ATP translocases are exclusive to eukaryotes and are thought to have evolved during
3875:
5405:
4931:
2450:
Aquila H, Misra D, Eulitz M, Klingenberg M (March 1982). "Complete amino acid sequence of the ADP/ATP carrier from beef heart mitochondria".
2293:
Bruni A, Luciani S, Contessa AR (March 1964). "Inhibition by atractyloside of the binding of adenine-nucleotides to rat-liver mitochondria".
1253:
1035:
uncovered an inhibitory effect of atractyloside on the energy-transfer system (oxidative phosphorylation) and ADP binding sites of rat liver
5689:
5684:
5679:
5263:
3131:
2800:
2567:
2379:
Pfaff E, Klingenberg M, Heldt HW (June 1965). "Unspecific permeation and specific exchange of adenine nucleotides in liver mitochondria".
4273:
3767:
2693:
2688:
2613:
2582:
775:
The translocase (as a molecular surface, green) viewed from both sides of a lipid bilayer representing the inner mitocondrial membrane.
535:
388:
243:
2213:"Biochemical structure of mitochondria. II. Radioactive labeling of intra-mitochondrial nucleotides during oxidative phosphorylation"
5659:
5560:
4727:
3689:
2987:
2901:
2658:
861:
Apart from exchange of ADP and ATP across the inner mitochondrial membrane, the ANT also exhibits an intrinsic uncoupling activity
3491:
523:
376:
231:
3752:
2828:
2673:
5600:
3227:
5694:
5580:
5575:
5546:
4087:
3651:
3453:
3448:
2575:
701:, which constitute more than 10% of the protein in the inner mitochondrial membrane. These proteins are classified under the
516:
369:
224:
176:
5699:
3646:
3641:
3636:
3621:
3616:
3611:
3606:
3396:
4972:
4774:
4574:
1857:"The reconstituted ADP/ATP carrier can mediate H+ transport by free fatty acids, which is further stimulated by mersalyl"
5570:
1464:"Yeast mitochondrial ADP/ATP carriers are monomeric in detergents as demonstrated by differential affinity purification"
659:
655:
3562:
4542:
4421:
4125:
752:
4494:
2997:
2606:
1271:"Conflict and cooperation in eukaryogenesis: implications for the timing of endosymbiosis and the evolution of sex"
799:
5151:
4807:
3300:
2487:"Sequences required for delivery and localization of the ADP/ATP translocator to the mitochondrial inner membrane"
1967:"Structures of yeast mitochondrial ADP/ATP carriers support a domain-based alternating-access transport mechanism"
991:
ADP/ATP translocase is very specifically inhibited by two families of compounds. The first family, which includes
771:
5555:
3443:
1080:
670:
5339:
5605:
3427:
3194:
2561:
2551:
2541:
1359:"Projection structure of the atractyloside-inhibited mitochondrial ADP/ATP carrier of Saccharomyces cerevisiae"
1048:
943:
5296:
164:
3823:
2557:
2547:
2537:
5565:
5197:
2926:
2027:
Ruprecht JJ, King MS, Zögg T, Aleksandrova AA, Pardon E, Crichton PG, Steyaert J, Kunji ER (January 2019).
1898:"Alterations in voltage-sensing of the mitochondrial permeability transition pore in ANT1-deficient cells"
851:
651:
528:
381:
236:
5541:
5377:
5063:
4248:
4173:
3567:
3438:
3433:
3007:
2609:
1070:
1004:
960:
847:
702:
663:
2254:"Intramitochondrial nucleotides. I. Some factors affecting net interconversions of adenine nucleotides"
798:
that form a barrel that results in a deep cone-shaped depression accessible from the outside where the
160:
5638:
5633:
3600:
3002:
2302:
2177:
1978:
1909:
1522:
1420:
1075:
1012:
996:
952:
928:
912:
674:
581:
434:
289:
5230:
2936:
2711:
2992:
2326:
2150:
1837:
1788:
1491:
1444:
1057:
920:
714:
669:
Free ADP is transported from the cytoplasm to the mitochondrial matrix, while ATP produced from
30:
5133:
5128:
4476:
4471:
4398:
4393:
4388:
4383:
4378:
4373:
4353:
4348:
4343:
4338:
4323:
4313:
4303:
4298:
4288:
4263:
4069:
4054:
4049:
3671:
3666:
3661:
2516:
2467:
2432:
2396:
2361:
2318:
2275:
2234:
2193:
2142:
2107:
2058:
2006:
1935:
1878:
1829:
1780:
1739:
1677:
1639:
1585:
1550:
1483:
1436:
1380:
1336:
1300:
1249:
1219:
1168:
1124:
964:
908:
779:
view from the intermembrane space. The protein is in the open conformation towards this side.
759:
151:
37:
5387:
5354:
5321:
5311:
5278:
5273:
5207:
5088:
5040:
5030:
4987:
4951:
4946:
4913:
4908:
4903:
4898:
4889:
4884:
4879:
4851:
4841:
4832:
4827:
4822:
4657:
4642:
4637:
4622:
4589:
4556:
4466:
4426:
4183:
4155:
4140:
4135:
4130:
4107:
4102:
3950:
3946:
3937:
3895:
3719:
3709:
3699:
3631:
3577:
3511:
3496:
3330:
3325:
3320:
3171:
3072:
3067:
3037:
2961:
2956:
2951:
2878:
5433:
3534:
3272:
3262:
3247:
3209:
3204:
3022:
2946:
2873:
2598:
2506:
2498:
2459:
2424:
2388:
2353:
2310:
2265:
2224:
2185:
2134:
2097:
2089:
2048:
2040:
1996:
1986:
1925:
1917:
1868:
1819:
1770:
1729:
1719:
1669:
1629:
1619:
1577:
1540:
1530:
1475:
1428:
1370:
1328:
1290:
1282:
1209:
1199:
1158:
1116:
956:
576:
429:
284:
1511:"The yeast mitochondrial ADP/ATP carrier functions as a monomer in mitochondrial membranes"
1107:
Klingenberg M (October 2008). "The ADP and ATP transport in mitochondria and its carrier".
483:
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
338:
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
191:
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
143:
5517:
2602:
1000:
948:
718:
605:
458:
313:
438:
293:
2306:
2181:
1982:
1913:
1526:
1424:
2102:
2077:
2053:
2028:
2001:
1966:
1930:
1897:
1734:
1699:
1545:
1510:
1295:
1270:
823:
682:
585:
2511:
2486:
2270:
2253:
2229:
2212:
1965:
Ruprecht JJ, Hellawell AM, Harding M, Crichton PG, McCoy AJ, Kunji ER (January 2014).
1873:
1856:
1624:
1607:
105:
93:
5673:
5533:
2428:
2392:
2357:
1016:
992:
932:
792:
2154:
1792:
69:
2330:
1841:
1608:"Molecular cloning of a cDNA for a human ADP/ATP carrier which is growth-regulated"
1568:
Kunji ER, Crichton PG (March 2010). "Mitochondrial carriers function as monomers".
1495:
1448:
1036:
916:
855:
139:
1775:
1758:
1606:
Battini R, Ferrari S, Kaczmarek L, Calabretta B, Chen ST, Baserga R (March 1987).
907:
ADP/ATP exchange is energetically expensive: about 25% of the energy yielded from
117:
2463:
2189:
1581:
1204:
1187:
1163:
1146:
1120:
552:
405:
260:
81:
5156:
4612:
4208:
3409:
878:
795:
615:
468:
323:
2044:
1971:
Proceedings of the
National Academy of Sciences of the United States of America
1515:
Proceedings of the
National Academy of Sciences of the United States of America
1188:"Discoveries, metabolic roles and diseases of mitochondrial carriers: A review"
5592:
4750:
1479:
983:
971:, or non-coding regions of DNA, which increases the likelihood of deleterious
874:
832:
827:
735:
559:
412:
267:
2138:
5529:
1991:
1535:
1046:
of ADP/ATP translocase was sequenced for bovine in 1982 and a yeast species
972:
839:
678:
2322:
2279:
2238:
2197:
2062:
2029:"The Molecular Mechanism of Transport by the Mitochondrial ADP/ATP Carrier"
2010:
1939:
1833:
1784:
1743:
1673:
1589:
1554:
1487:
1440:
1384:
1375:
1358:
1304:
1286:
1223:
1172:
1128:
2520:
2471:
2436:
2400:
2365:
2146:
2111:
1882:
1708:-ATPase reversal: critical role of matrix substrate-level phosphorylation"
1681:
1643:
1340:
5123:
5118:
5113:
5045:
4662:
4403:
4368:
4363:
4358:
4333:
4328:
4318:
4308:
4293:
4283:
4278:
4268:
4258:
4253:
4243:
4233:
4228:
4223:
4064:
4059:
4044:
4039:
4034:
4029:
4024:
4019:
3789:
3656:
2983:
2093:
1724:
807:
803:
698:
564:
417:
272:
76:
2502:
2125:
Rose MR (January 1998). "Mitochondrial myopathies: genetic mechanisms".
1634:
1432:
1332:
1214:
5490:
5485:
5480:
5475:
5470:
5465:
5415:
5410:
5382:
5359:
5349:
5344:
5316:
5306:
5301:
5268:
5212:
5202:
5108:
5103:
5098:
5093:
5083:
5078:
5073:
5068:
5035:
5025:
5020:
5015:
4992:
4982:
4977:
4954:
4941:
4936:
4870:
4865:
4856:
4846:
4817:
4812:
4789:
4784:
4779:
4756:
4732:
4709:
4652:
4647:
4632:
4627:
4617:
4594:
4584:
4579:
4551:
4546:
4524:
4519:
4514:
4509:
4504:
4499:
4461:
4456:
4451:
4446:
4441:
4436:
4431:
4218:
4213:
4203:
4198:
4193:
4188:
4178:
4150:
4145:
4097:
4092:
4014:
4009:
4004:
3999:
3994:
3989:
3984:
3979:
3974:
3932:
3923:
3914:
3909:
3900:
3890:
3885:
3880:
3834:
3829:
3805:
3800:
3795:
3734:
3729:
3724:
3714:
3704:
3694:
3626:
3582:
3572:
3544:
3539:
3516:
3506:
3501:
3473:
3468:
3463:
3458:
3406:
3401:
3357:
3352:
3347:
3342:
3335:
3315:
3310:
3305:
3282:
3277:
3176:
3166:
3161:
3087:
3082:
3077:
3062:
3057:
3052:
3047:
3042:
2883:
2781:
2776:
2771:
2766:
2761:
1027:
968:
843:
740:
731:
725:
694:
690:
686:
496:
204:
2314:
1921:
1824:
1807:
763:
41:
5614:
4703:
4238:
3785:
3267:
3257:
3252:
3242:
3237:
3232:
3199:
3156:
3151:
3146:
3141:
3123:
3118:
3113:
3108:
3032:
3027:
3017:
3012:
2979:
2941:
2931:
2921:
2916:
2906:
2868:
2863:
2858:
2853:
2848:
2843:
2838:
2833:
2810:
2805:
2756:
2746:
2741:
2683:
2678:
2668:
2663:
811:
547:
400:
255:
171:
2485:
Adrian GS, McCammon MT, Montgomery DL, Douglas MG (February 1986).
3762:
3757:
2911:
2751:
2736:
2731:
2726:
2721:
2716:
982:
770:
751:
1509:
Bamber L, Harding M, Monné M, Slotboom DJ, Kunji ER (June 2007).
35:
Cytoplasmic view of the binding pocket of ATP–ADP translocase 1,
5245:
5240:
5235:
3136:
1043:
540:
393:
248:
133:
88:
64:
5515:
5454:
5179:
5011:
System A & N, sodium-coupled neutral amino-acid transporter
4685:
3857:
3378:
2640:
2625:
2571:
1147:"The transport mechanism of the mitochondrial ADP/ATP carrier"
814:
38, have been shown to be essential for transporter activity.
783:
view from the matrix. The protein is closed towards this side.
1700:"Forward operation of adenine nucleotide translocase during F
1192:
Biochimica et
Biophysica Acta (BBA) - Molecular Cell Research
1151:
Biochimica et
Biophysica Acta (BBA) - Molecular Cell Research
1056:
sequenced a cDNA clone of the human transporter in 1989. The
2659:
high affinity glutamate and neutral amino-acid transporter
1759:"Mitochondrial consumption of cytosolic ATP: not so fast"
3105:
cationic amino-acid transporter/glycoprotein-associated
3130:
glycoprotein-associated/light or catalytic subunits of
2381:
Biochimica et
Biophysica Acta (BBA) - General Subjects
2076:
Harding AE, Petty RK, Morgan-Hughes JA (August 1988).
2078:"Mitochondrial myopathy: a genetic study of 71 cases"
1406:
1404:
1402:
1400:
1398:
1396:
1394:
802:
binds. The binding pocket, conserved throughout most
5264:
Na-independent, system-L like amino-acid transporter
2452:
5591:
5528:
5426:
5398:
5370:
5332:
5289:
5256:
5223:
5190:
5144:
5056:
5003:
4965:
4924:
4800:
4767:
4743:
4720:
4696:
4605:
4567:
4535:
4487:
4414:
4166:
4118:
4080:
3962:
3868:
3816:
3778:
3745:
3682:
3593:
3555:
3527:
3484:
3420:
3389:
3293:
3220:
3187:
3098:
2972:
2894:
2821:
2792:
2704:
2651:
1693:
1691:
1570:
Biochimica et
Biophysica Acta (BBA) - Bioenergetics
650:) or mitochondrial ADP/ATP carrier, exchanges free
611:
601:
596:
575:
570:
558:
546:
534:
522:
510:
502:
492:
487:
482:
464:
454:
449:
428:
423:
411:
399:
387:
375:
363:
355:
347:
342:
337:
319:
309:
304:
283:
278:
266:
254:
242:
230:
218:
210:
200:
195:
190:
170:
150:
132:
127:
111:
99:
87:
75:
63:
55:
50:
23:
1109:Biochimica et Biophysica Acta (BBA) - Biomembranes
1102:
1100:
1098:
1096:
1269:Radzvilavicius AL, Blackstone NW (October 2015).
685:. Human cells express four ADP/ATP translocases:
2022:
2020:
1960:
1958:
1808:"The "B space" of mitochondrial phosphorylation"
1194:. Channels and transporters in cell metabolism.
1153:. Channels and transporters in cell metabolism.
1026:In 1955, Siekevitz and Potter demonstrated that
838:ANT transports the free, i.e. deprotonated, non-
810:residues 96, 204, 252, 253, and 294, as well as
1855:Brustovetsky N, Klingenberg M (November 1994).
1601:
1599:
1462:Bamber L, Slotboom DJ, Kunji ER (August 2007).
1655:
1653:
858:are not necessarily in directional synchrony.
728:– found primarily in heart and skeletal muscle
2583:
963:patterns but is characterized by large-scale
8:
1352:
1350:
1248:. San Francisco: W.H. Freeman. p. 553.
1140:
1138:
826:unfavorable reactions. After the consequent
3970:organic cation/anion/zwitterion transporter
1239:
1237:
1235:
1233:
5525:
5512:
5451:
5187:
5176:
4693:
4682:
3865:
3854:
3492:human Na-sulfate/carboxylate cotransporter
3386:
3375:
2648:
2637:
2633:
2622:
2590:
2576:
2568:
1015:, or in the matrix state by the inhibitor
931:, or in the matrix state by the inhibitor
658:. ANT is the most abundant protein in the
593:
446:
301:
124:
29:
2560:at the U.S. National Library of Medicine
2550:at the U.S. National Library of Medicine
2540:at the U.S. National Library of Medicine
2510:
2269:
2228:
2101:
2052:
2000:
1990:
1929:
1872:
1823:
1774:
1733:
1723:
1633:
1623:
1544:
1534:
1374:
1294:
1213:
1203:
1162:
4088:Na+-dependent ascorbic acid transporter
2417:Archives of Biochemistry and Biophysics
2344:Duee ED, Vignais PV (August 1965). "".
1275:Journal of the Royal Society, Interface
1244:Stryer L, Berg JM, Tymoczko JL (2007).
1092:
923:that is tapped by ADP/ATP translocase.
3876:Organic anion-transporting polypeptide
1357:Kunji ER, Harding M (September 2003).
967:(mtDNA) deletions. mtDNA contains few
479:
334:
187:
20:
4932:proton-coupled amino-acid transporter
3132:heterodimeric amino-acid transporters
2801:heterodimeric amino-acid transporters
7:
3397:proton coupled metal ion transporter
2211:Siekevitz P, Potter VR (July 1955).
1186:Palmieri F, Monné M (October 2016).
4973:sugar-phosphate/phosphate exchanger
4575:facilitative nucleoside transporter
2258:The Journal of Biological Chemistry
2217:The Journal of Biological Chemistry
1861:The Journal of Biological Chemistry
1612:The Journal of Biological Chemistry
1363:The Journal of Biological Chemistry
4775:type II Na-phosphate cotransporter
2988:sodium:neurotransmitter symporters
14:
4728:Vesicular glutamate transporter 1
3690:Vesicular glutamate transporter 1
3563:proton oligopeptide cotransporter
2558:Adenine+Nucleotide+Translocator+3
2548:Adenine+Nucleotide+Translocator+2
2538:Adenine+Nucleotide+Translocator+1
942:Rare but severe diseases such as
1812:Journal of Neuroscience Research
919:, is consumed to regenerate the
4543:Na-coupled nucleoside transport
4422:multifunctional anion exchanger
3753:vesicular monoamine transporter
1806:Chinopoulos C (December 2011).
1052:in 1986 before finally Battini
884:The net process is denoted by:
881:recognized by the translocase.
628:Adenine nucleotide translocator
2491:Molecular and Cellular Biology
1:
5406:multidrug and toxin extrusion
4495:fatty acid transport proteins
2712:facilitative GLUT transporter
2346:Biochimica et Biophysica Acta
2271:10.1016/S0021-9258(19)77415-8
2230:10.1016/S0021-9258(18)66032-6
1874:10.1016/S0021-9258(18)46989-X
1776:10.1016/j.febslet.2011.04.004
1625:10.1016/S0021-9258(18)61355-9
713:In humans, there exist three
128:Available protein structures:
5152:basolateral iron transporter
4808:nucleoside-sugar transporter
3301:sodium bile salt cotransport
2902:sodium glucose cotransporter
2464:10.1515/bchm2.1982.363.1.345
2429:10.1016/0003-9861(76)90231-9
2393:10.1016/0304-4165(65)90258-8
2358:10.1016/0304-4165(65)90419-8
2190:10.1126/science.289.5480.782
1662:Journal of Molecular Biology
1582:10.1016/j.bbabio.2010.03.023
1468:Journal of Molecular Biology
1205:10.1016/j.bbamcr.2016.03.007
1164:10.1016/j.bbamcr.2016.03.015
1121:10.1016/j.bbamem.2008.04.011
743:– primarily express in liver
660:inner mitochondrial membrane
656:inner mitochondrial membrane
5690:Genes on human chromosome Y
5685:Genes on human chromosome X
5680:Genes on human chromosome 4
2607:membrane transport proteins
2082:Journal of Medical Genetics
16:Class of transport proteins
5716:
5340:Putative sugar transporter
2045:10.1016/j.cell.2018.11.025
1757:Chinopoulos C (May 2011).
5655:
5524:
5511:
5461:
5450:
5186:
5175:
4692:
4681:
3864:
3853:
3385:
3374:
2647:
2636:
2632:
2621:
2252:Pressman BC (June 1958).
1480:10.1016/j.jmb.2007.05.072
1081:Oxidative phosphorylation
734:– primarily expressed in
671:oxidative phosphorylation
654:with free ADP across the
592:
445:
300:
123:
28:
5660:solute carrier disorders
5297:Choline-like transporter
3428:electroneutral cation-Cl
2562:Medical Subject Headings
2552:Medical Subject Headings
2542:Medical Subject Headings
2139:10.1001/archneur.55.1.17
1049:Saccharomyces cerevisiae
944:mitochondrial myopathies
673:is transported from the
5198:Magnesium transporter E
2829:bicarbonate transporter
1992:10.1073/pnas.1320692111
1536:10.1073/pnas.0703969104
644:ADP/ATP carrier protein
5593:Antiporter (exchanger)
1674:10.1006/jmbi.1993.1233
1376:10.1074/jbc.C300304200
1287:10.1098/rsif.2015.0584
988:
784:
768:
5695:Solute carrier family
5064:metal ion transporter
4174:mitochondrial carrier
3824:type III Na-phosphate
2127:Archives of Neurology
1071:Mitochondrial carrier
986:
961:Mendelian inheritance
955:progressive external
869:Translocase mechanism
774:
755:
703:mitochondrial carrier
664:mitochondrial carrier
634:), also known as the
5700:Cellular respiration
2094:10.1136/jmg.25.8.528
1725:10.1096/fj.09-149898
1076:Cellular respiration
1013:carboxyatractyloside
997:carboxyatractyloside
929:carboxyatractyloside
675:mitochondrial matrix
24:ADP/ATP translocases
5231:Ammonia transporter
4126:Na/(Ca-K) exchanger
2503:10.1128/mcb.6.2.626
2307:1964Natur.201.1219B
2182:2000Sci...289..782K
1983:2014PNAS..111E.426R
1914:2016NatSR...626700D
1527:2007PNAS..10410830B
1433:10.1038/nature02056
1425:2003Natur.426...39P
1333:10.1021/bi00329a029
913:aerobic respiration
662:and belongs to the
636:ADP/ATP translocase
5378:Folate transporter
2799:heavy subunits of
2039:(3): 435–447.e15.
1902:Scientific Reports
989:
953:autosomal dominant
921:membrane potential
856:F0-F1 ATP synthase
785:
769:
5667:
5666:
5651:
5650:
5647:
5646:
5507:
5506:
5503:
5502:
5499:
5498:
5446:
5445:
5442:
5441:
5171:
5170:
5167:
5166:
4677:
4676:
4673:
4672:
3849:
3848:
3845:
3844:
3370:
3369:
3366:
3365:
2599:Membrane proteins
2315:10.1038/2011219a0
1922:10.1038/srep26700
1825:10.1002/jnr.22659
1281:(111): 20150584.
1255:978-0-7167-8724-2
1115:(10): 1978–2021.
965:mitochondrial DNA
909:electron transfer
824:thermodynamically
625:
624:
621:
620:
478:
477:
474:
473:
333:
332:
329:
328:
186:
185:
182:
181:
177:structure summary
5707:
5626:
5625:
5624:
5526:
5513:
5452:
5434:Heme transporter
5188:
5177:
4694:
4683:
3866:
3855:
3535:urea transporter
3387:
3376:
2649:
2638:
2634:
2623:
2603:carrier proteins
2592:
2585:
2578:
2569:
2525:
2524:
2514:
2482:
2476:
2475:
2447:
2441:
2440:
2411:
2405:
2404:
2376:
2370:
2369:
2341:
2335:
2334:
2290:
2284:
2283:
2273:
2249:
2243:
2242:
2232:
2208:
2202:
2201:
2165:
2159:
2158:
2122:
2116:
2115:
2105:
2073:
2067:
2066:
2056:
2024:
2015:
2014:
2004:
1994:
1962:
1953:
1950:
1944:
1943:
1933:
1893:
1887:
1886:
1876:
1867:(44): 27329–36.
1852:
1846:
1845:
1827:
1818:(12): 1897–904.
1803:
1797:
1796:
1778:
1754:
1748:
1747:
1737:
1727:
1695:
1686:
1685:
1657:
1648:
1647:
1637:
1627:
1603:
1594:
1593:
1565:
1559:
1558:
1548:
1538:
1506:
1500:
1499:
1459:
1453:
1452:
1408:
1389:
1388:
1378:
1354:
1345:
1344:
1315:
1309:
1308:
1298:
1266:
1260:
1259:
1241:
1228:
1227:
1217:
1207:
1183:
1177:
1176:
1166:
1142:
1133:
1132:
1104:
1017:bongkrekic acid.
933:bongkrekic acid.
781:Right panel (M):
777:Left panel (IM):
766:
594:
480:
447:
335:
302:
214:PEO3, PEO2, ANT1
188:
125:
44:
33:
21:
5715:
5714:
5710:
5709:
5708:
5706:
5705:
5704:
5670:
5669:
5668:
5663:
5643:
5623:
5620:
5619:
5618:
5616:
5587:
5550:
5520:
5495:
5457:
5438:
5422:
5394:
5366:
5328:
5285:
5252:
5219:
5182:
5163:
5140:
5052:
4999:
4961:
4920:
4796:
4763:
4739:
4716:
4688:
4669:
4601:
4563:
4531:
4483:
4410:
4162:
4114:
4076:
3958:
3860:
3841:
3812:
3774:
3741:
3678:
3601:monocarboxylate
3589:
3551:
3523:
3480:
3416:
3381:
3362:
3289:
3216:
3195:Na/Ca exchanger
3183:
3094:
2968:
2890:
2817:
2788:
2700:
2643:
2628:
2617:
2596:
2534:
2529:
2528:
2484:
2483:
2479:
2449:
2448:
2444:
2413:
2412:
2408:
2378:
2377:
2373:
2343:
2342:
2338:
2292:
2291:
2287:
2251:
2250:
2246:
2210:
2209:
2205:
2176:(5480): 782–5.
2167:
2166:
2162:
2124:
2123:
2119:
2075:
2074:
2070:
2026:
2025:
2018:
1964:
1963:
1956:
1951:
1947:
1895:
1894:
1890:
1854:
1853:
1849:
1805:
1804:
1800:
1756:
1755:
1751:
1707:
1703:
1697:
1696:
1689:
1659:
1658:
1651:
1605:
1604:
1597:
1576:(6–7): 817–31.
1567:
1566:
1562:
1521:(26): 10830–4.
1508:
1507:
1503:
1461:
1460:
1456:
1419:(6962): 39–44.
1410:
1409:
1392:
1369:(39): 36985–8.
1356:
1355:
1348:
1317:
1316:
1312:
1268:
1267:
1263:
1256:
1243:
1242:
1231:
1198:(10): 2362–78.
1185:
1184:
1180:
1157:(10): 2379–93.
1144:
1143:
1136:
1106:
1105:
1094:
1089:
1067:
1024:
1008:
1001:bongkrekic acid
987:Bongkrekic acid
981:
957:ophthalmoplegia
949:skeletal muscle
940:
903:
899:
895:
891:
871:
846:bound forms of
820:
758:
750:
711:
101:OPM superfamily
46:
36:
17:
12:
11:
5:
5713:
5711:
5703:
5702:
5697:
5692:
5687:
5682:
5672:
5671:
5665:
5664:
5656:
5653:
5652:
5649:
5648:
5645:
5644:
5642:
5641:
5636:
5631:
5630:
5629:
5621:
5603:
5597:
5595:
5589:
5588:
5586:
5585:
5584:
5583:
5578:
5568:
5563:
5558:
5553:
5548:
5544:
5538:
5536:
5522:
5521:
5516:
5509:
5508:
5505:
5504:
5501:
5500:
5497:
5496:
5494:
5493:
5488:
5483:
5478:
5473:
5468:
5462:
5459:
5458:
5455:
5448:
5447:
5444:
5443:
5440:
5439:
5437:
5436:
5430:
5428:
5424:
5423:
5421:
5420:
5419:
5418:
5413:
5402:
5400:
5396:
5395:
5393:
5392:
5391:
5390:
5385:
5374:
5372:
5368:
5367:
5365:
5364:
5363:
5362:
5357:
5352:
5347:
5336:
5334:
5330:
5329:
5327:
5326:
5325:
5324:
5319:
5314:
5309:
5304:
5293:
5291:
5287:
5286:
5284:
5283:
5282:
5281:
5276:
5271:
5260:
5258:
5254:
5253:
5251:
5250:
5249:
5248:
5243:
5238:
5227:
5225:
5221:
5220:
5218:
5217:
5216:
5215:
5210:
5205:
5194:
5192:
5184:
5183:
5180:
5173:
5172:
5169:
5168:
5165:
5164:
5162:
5161:
5160:
5159:
5148:
5146:
5142:
5141:
5139:
5138:
5137:
5136:
5131:
5126:
5121:
5116:
5111:
5106:
5101:
5096:
5091:
5086:
5081:
5076:
5071:
5060:
5058:
5054:
5053:
5051:
5050:
5049:
5048:
5043:
5038:
5033:
5028:
5023:
5018:
5007:
5005:
5001:
5000:
4998:
4997:
4996:
4995:
4990:
4985:
4980:
4969:
4967:
4963:
4962:
4960:
4959:
4958:
4957:
4949:
4944:
4939:
4928:
4926:
4922:
4921:
4919:
4918:
4917:
4916:
4911:
4906:
4901:
4894:
4893:
4892:
4887:
4882:
4875:
4874:
4873:
4868:
4861:
4860:
4859:
4854:
4849:
4844:
4837:
4836:
4835:
4830:
4825:
4820:
4815:
4804:
4802:
4798:
4797:
4795:
4794:
4793:
4792:
4787:
4782:
4771:
4769:
4765:
4764:
4762:
4761:
4760:
4759:
4747:
4745:
4741:
4740:
4738:
4737:
4736:
4735:
4724:
4722:
4718:
4717:
4715:
4714:
4713:
4712:
4700:
4698:
4690:
4689:
4686:
4679:
4678:
4675:
4674:
4671:
4670:
4668:
4667:
4666:
4665:
4660:
4655:
4650:
4645:
4640:
4635:
4630:
4625:
4620:
4609:
4607:
4603:
4602:
4600:
4599:
4598:
4597:
4592:
4587:
4582:
4571:
4569:
4565:
4564:
4562:
4561:
4560:
4559:
4554:
4539:
4537:
4533:
4532:
4530:
4529:
4528:
4527:
4522:
4517:
4512:
4507:
4502:
4491:
4489:
4485:
4484:
4482:
4481:
4480:
4479:
4474:
4469:
4464:
4459:
4454:
4449:
4444:
4439:
4434:
4429:
4418:
4416:
4412:
4411:
4409:
4408:
4407:
4406:
4401:
4396:
4391:
4386:
4381:
4376:
4371:
4366:
4361:
4356:
4351:
4346:
4341:
4336:
4331:
4326:
4321:
4316:
4311:
4306:
4301:
4296:
4291:
4286:
4281:
4276:
4271:
4266:
4261:
4256:
4251:
4246:
4241:
4236:
4231:
4226:
4221:
4216:
4211:
4206:
4201:
4196:
4191:
4186:
4181:
4170:
4168:
4164:
4163:
4161:
4160:
4159:
4158:
4153:
4148:
4143:
4138:
4133:
4122:
4120:
4116:
4115:
4113:
4112:
4111:
4110:
4105:
4100:
4095:
4084:
4082:
4078:
4077:
4075:
4074:
4073:
4072:
4067:
4062:
4057:
4052:
4047:
4042:
4037:
4032:
4027:
4022:
4017:
4012:
4007:
4002:
3997:
3992:
3987:
3982:
3977:
3966:
3964:
3960:
3959:
3957:
3956:
3955:
3954:
3942:
3941:
3940:
3935:
3928:
3927:
3926:
3919:
3918:
3917:
3912:
3905:
3904:
3903:
3898:
3893:
3888:
3883:
3872:
3870:
3862:
3861:
3858:
3851:
3850:
3847:
3846:
3843:
3842:
3840:
3839:
3838:
3837:
3832:
3826:cotransporter
3820:
3818:
3814:
3813:
3811:
3810:
3809:
3808:
3803:
3798:
3782:
3780:
3776:
3775:
3773:
3772:
3771:
3770:
3765:
3760:
3749:
3747:
3743:
3742:
3740:
3739:
3738:
3737:
3732:
3727:
3722:
3717:
3712:
3707:
3702:
3697:
3686:
3684:
3680:
3679:
3677:
3676:
3675:
3674:
3669:
3664:
3659:
3654:
3649:
3644:
3639:
3634:
3629:
3624:
3619:
3614:
3609:
3597:
3595:
3591:
3590:
3588:
3587:
3586:
3585:
3580:
3575:
3570:
3559:
3557:
3553:
3552:
3550:
3549:
3548:
3547:
3542:
3531:
3529:
3525:
3524:
3522:
3521:
3520:
3519:
3514:
3509:
3504:
3499:
3488:
3486:
3482:
3481:
3479:
3478:
3477:
3476:
3471:
3466:
3461:
3456:
3451:
3446:
3441:
3436:
3430:cotransporter
3424:
3422:
3418:
3417:
3415:
3414:
3413:
3412:
3404:
3393:
3391:
3383:
3382:
3379:
3372:
3371:
3368:
3367:
3364:
3363:
3361:
3360:
3355:
3350:
3345:
3340:
3339:
3338:
3333:
3328:
3323:
3318:
3313:
3308:
3297:
3295:
3291:
3290:
3288:
3287:
3286:
3285:
3280:
3275:
3270:
3265:
3260:
3255:
3250:
3245:
3240:
3235:
3228:Na/H exchanger
3224:
3222:
3218:
3217:
3215:
3214:
3213:
3212:
3207:
3202:
3191:
3189:
3185:
3184:
3182:
3181:
3180:
3179:
3174:
3169:
3164:
3159:
3154:
3149:
3144:
3139:
3128:
3127:
3126:
3121:
3116:
3111:
3102:
3100:
3096:
3095:
3093:
3092:
3091:
3090:
3085:
3080:
3075:
3070:
3065:
3060:
3055:
3050:
3045:
3040:
3035:
3030:
3025:
3020:
3015:
3010:
3005:
3000:
2995:
2976:
2974:
2970:
2969:
2967:
2966:
2965:
2964:
2959:
2954:
2949:
2944:
2939:
2934:
2929:
2924:
2919:
2914:
2909:
2898:
2896:
2892:
2891:
2889:
2888:
2887:
2886:
2881:
2876:
2871:
2866:
2861:
2856:
2851:
2846:
2841:
2836:
2825:
2823:
2819:
2818:
2816:
2815:
2814:
2813:
2808:
2796:
2794:
2790:
2789:
2787:
2786:
2785:
2784:
2779:
2774:
2769:
2764:
2759:
2754:
2749:
2744:
2739:
2734:
2729:
2724:
2719:
2708:
2706:
2702:
2701:
2699:
2698:
2697:
2696:
2691:
2686:
2681:
2676:
2671:
2666:
2655:
2653:
2645:
2644:
2641:
2630:
2629:
2626:
2619:
2618:
2610:solute carrier
2597:
2595:
2594:
2587:
2580:
2572:
2566:
2565:
2555:
2545:
2533:
2532:External links
2530:
2527:
2526:
2477:
2442:
2406:
2371:
2336:
2301:(1): 1219–20.
2285:
2244:
2203:
2160:
2117:
2068:
2016:
1977:(4): E426-34.
1954:
1945:
1888:
1847:
1798:
1749:
1718:(7): 2405–16.
1705:
1701:
1687:
1668:(4): 1159–70.
1649:
1595:
1560:
1501:
1454:
1390:
1346:
1310:
1261:
1254:
1229:
1178:
1134:
1091:
1090:
1088:
1085:
1084:
1083:
1078:
1073:
1066:
1063:
1023:
1020:
1006:
980:
977:
939:
936:
905:
904:
901:
897:
893:
889:
870:
867:
835:implications.
819:
816:
749:
746:
745:
744:
738:
729:
710:
707:
683:eukaryogenesis
623:
622:
619:
618:
613:
609:
608:
603:
599:
598:
590:
589:
579:
573:
572:
568:
567:
562:
556:
555:
550:
544:
543:
538:
532:
531:
526:
520:
519:
514:
508:
507:
504:
500:
499:
494:
490:
489:
485:
484:
476:
475:
472:
471:
466:
462:
461:
456:
452:
451:
443:
442:
432:
426:
425:
421:
420:
415:
409:
408:
403:
397:
396:
391:
385:
384:
379:
373:
372:
367:
361:
360:
357:
353:
352:
349:
345:
344:
340:
339:
331:
330:
327:
326:
321:
317:
316:
311:
307:
306:
298:
297:
287:
281:
280:
276:
275:
270:
264:
263:
258:
252:
251:
246:
240:
239:
234:
228:
227:
222:
216:
215:
212:
208:
207:
202:
198:
197:
193:
192:
184:
183:
180:
179:
174:
168:
167:
154:
148:
147:
137:
130:
129:
121:
120:
115:
109:
108:
103:
97:
96:
91:
85:
84:
79:
73:
72:
67:
61:
60:
59:Aden_trnslctor
57:
53:
52:
48:
47:
34:
26:
25:
15:
13:
10:
9:
6:
4:
3:
2:
5712:
5701:
5698:
5696:
5693:
5691:
5688:
5686:
5683:
5681:
5678:
5677:
5675:
5662:
5661:
5654:
5640:
5637:
5635:
5632:
5628:
5612:
5609:
5608:
5607:
5604:
5602:
5599:
5598:
5596:
5594:
5590:
5582:
5579:
5577:
5574:
5573:
5572:
5569:
5567:
5564:
5562:
5559:
5557:
5554:
5552:
5545:
5543:
5540:
5539:
5537:
5535:
5534:Cotransporter
5531:
5527:
5523:
5519:
5514:
5510:
5492:
5489:
5487:
5484:
5482:
5479:
5477:
5474:
5472:
5469:
5467:
5464:
5463:
5460:
5453:
5449:
5435:
5432:
5431:
5429:
5425:
5417:
5414:
5412:
5409:
5408:
5407:
5404:
5403:
5401:
5397:
5389:
5386:
5384:
5381:
5380:
5379:
5376:
5375:
5373:
5369:
5361:
5358:
5356:
5353:
5351:
5348:
5346:
5343:
5342:
5341:
5338:
5337:
5335:
5331:
5323:
5320:
5318:
5315:
5313:
5310:
5308:
5305:
5303:
5300:
5299:
5298:
5295:
5294:
5292:
5288:
5280:
5277:
5275:
5272:
5270:
5267:
5266:
5265:
5262:
5261:
5259:
5255:
5247:
5244:
5242:
5239:
5237:
5234:
5233:
5232:
5229:
5228:
5226:
5222:
5214:
5211:
5209:
5206:
5204:
5201:
5200:
5199:
5196:
5195:
5193:
5189:
5185:
5178:
5174:
5158:
5155:
5154:
5153:
5150:
5149:
5147:
5143:
5135:
5132:
5130:
5127:
5125:
5122:
5120:
5117:
5115:
5112:
5110:
5107:
5105:
5102:
5100:
5097:
5095:
5092:
5090:
5087:
5085:
5082:
5080:
5077:
5075:
5072:
5070:
5067:
5066:
5065:
5062:
5061:
5059:
5055:
5047:
5044:
5042:
5039:
5037:
5034:
5032:
5029:
5027:
5024:
5022:
5019:
5017:
5014:
5013:
5012:
5009:
5008:
5006:
5002:
4994:
4991:
4989:
4986:
4984:
4981:
4979:
4976:
4975:
4974:
4971:
4970:
4968:
4964:
4956:
4953:
4950:
4948:
4945:
4943:
4940:
4938:
4935:
4934:
4933:
4930:
4929:
4927:
4923:
4915:
4912:
4910:
4907:
4905:
4902:
4900:
4897:
4896:
4895:
4891:
4888:
4886:
4883:
4881:
4878:
4877:
4876:
4872:
4869:
4867:
4864:
4863:
4862:
4858:
4855:
4853:
4850:
4848:
4845:
4843:
4840:
4839:
4838:
4834:
4831:
4829:
4826:
4824:
4821:
4819:
4816:
4814:
4811:
4810:
4809:
4806:
4805:
4803:
4799:
4791:
4788:
4786:
4783:
4781:
4778:
4777:
4776:
4773:
4772:
4770:
4766:
4758:
4755:
4754:
4752:
4749:
4748:
4746:
4742:
4734:
4731:
4730:
4729:
4726:
4725:
4723:
4719:
4711:
4708:
4707:
4705:
4702:
4701:
4699:
4695:
4691:
4684:
4680:
4664:
4661:
4659:
4656:
4654:
4651:
4649:
4646:
4644:
4641:
4639:
4636:
4634:
4631:
4629:
4626:
4624:
4621:
4619:
4616:
4615:
4614:
4611:
4610:
4608:
4604:
4596:
4593:
4591:
4588:
4586:
4583:
4581:
4578:
4577:
4576:
4573:
4572:
4570:
4566:
4558:
4555:
4553:
4550:
4549:
4548:
4544:
4541:
4540:
4538:
4534:
4526:
4523:
4521:
4518:
4516:
4513:
4511:
4508:
4506:
4503:
4501:
4498:
4497:
4496:
4493:
4492:
4490:
4486:
4478:
4475:
4473:
4470:
4468:
4465:
4463:
4460:
4458:
4455:
4453:
4450:
4448:
4445:
4443:
4440:
4438:
4435:
4433:
4430:
4428:
4425:
4424:
4423:
4420:
4419:
4417:
4413:
4405:
4402:
4400:
4397:
4395:
4392:
4390:
4387:
4385:
4382:
4380:
4377:
4375:
4372:
4370:
4367:
4365:
4362:
4360:
4357:
4355:
4352:
4350:
4347:
4345:
4342:
4340:
4337:
4335:
4332:
4330:
4327:
4325:
4322:
4320:
4317:
4315:
4312:
4310:
4307:
4305:
4302:
4300:
4297:
4295:
4292:
4290:
4287:
4285:
4282:
4280:
4277:
4275:
4272:
4270:
4267:
4265:
4262:
4260:
4257:
4255:
4252:
4250:
4247:
4245:
4242:
4240:
4237:
4235:
4232:
4230:
4227:
4225:
4222:
4220:
4217:
4215:
4212:
4210:
4207:
4205:
4202:
4200:
4197:
4195:
4192:
4190:
4187:
4185:
4182:
4180:
4177:
4176:
4175:
4172:
4171:
4169:
4165:
4157:
4154:
4152:
4149:
4147:
4144:
4142:
4139:
4137:
4134:
4132:
4129:
4128:
4127:
4124:
4123:
4121:
4117:
4109:
4106:
4104:
4101:
4099:
4096:
4094:
4091:
4090:
4089:
4086:
4085:
4083:
4079:
4071:
4068:
4066:
4063:
4061:
4058:
4056:
4053:
4051:
4048:
4046:
4043:
4041:
4038:
4036:
4033:
4031:
4028:
4026:
4023:
4021:
4018:
4016:
4013:
4011:
4008:
4006:
4003:
4001:
3998:
3996:
3993:
3991:
3988:
3986:
3983:
3981:
3978:
3976:
3973:
3972:
3971:
3968:
3967:
3965:
3961:
3952:
3948:
3945:
3944:
3943:
3939:
3936:
3934:
3931:
3930:
3929:
3925:
3922:
3921:
3920:
3916:
3913:
3911:
3908:
3907:
3906:
3902:
3899:
3897:
3894:
3892:
3889:
3887:
3884:
3882:
3879:
3878:
3877:
3874:
3873:
3871:
3867:
3863:
3856:
3852:
3836:
3833:
3831:
3828:
3827:
3825:
3822:
3821:
3819:
3815:
3807:
3804:
3802:
3799:
3797:
3794:
3793:
3791:
3787:
3784:
3783:
3781:
3777:
3769:
3766:
3764:
3761:
3759:
3756:
3755:
3754:
3751:
3750:
3748:
3744:
3736:
3733:
3731:
3728:
3726:
3723:
3721:
3718:
3716:
3713:
3711:
3708:
3706:
3703:
3701:
3698:
3696:
3693:
3692:
3691:
3688:
3687:
3685:
3681:
3673:
3670:
3668:
3665:
3663:
3660:
3658:
3655:
3653:
3650:
3648:
3645:
3643:
3640:
3638:
3635:
3633:
3630:
3628:
3625:
3623:
3620:
3618:
3615:
3613:
3610:
3608:
3605:
3604:
3602:
3599:
3598:
3596:
3592:
3584:
3581:
3579:
3576:
3574:
3571:
3569:
3566:
3565:
3564:
3561:
3560:
3558:
3554:
3546:
3543:
3541:
3538:
3537:
3536:
3533:
3532:
3530:
3526:
3518:
3515:
3513:
3510:
3508:
3505:
3503:
3500:
3498:
3495:
3494:
3493:
3490:
3489:
3487:
3483:
3475:
3472:
3470:
3467:
3465:
3462:
3460:
3457:
3455:
3452:
3450:
3447:
3445:
3442:
3440:
3437:
3435:
3432:
3431:
3429:
3426:
3425:
3423:
3419:
3411:
3408:
3405:
3403:
3400:
3399:
3398:
3395:
3394:
3392:
3388:
3384:
3377:
3373:
3359:
3356:
3354:
3351:
3349:
3346:
3344:
3341:
3337:
3334:
3332:
3329:
3327:
3324:
3322:
3319:
3317:
3314:
3312:
3309:
3307:
3304:
3303:
3302:
3299:
3298:
3296:
3292:
3284:
3281:
3279:
3276:
3274:
3271:
3269:
3266:
3264:
3261:
3259:
3256:
3254:
3251:
3249:
3246:
3244:
3241:
3239:
3236:
3234:
3231:
3230:
3229:
3226:
3225:
3223:
3219:
3211:
3208:
3206:
3203:
3201:
3198:
3197:
3196:
3193:
3192:
3190:
3186:
3178:
3175:
3173:
3170:
3168:
3165:
3163:
3160:
3158:
3155:
3153:
3150:
3148:
3145:
3143:
3140:
3138:
3135:
3134:
3133:
3129:
3125:
3122:
3120:
3117:
3115:
3112:
3110:
3107:
3106:
3104:
3103:
3101:
3097:
3089:
3086:
3084:
3081:
3079:
3076:
3074:
3071:
3069:
3066:
3064:
3061:
3059:
3056:
3054:
3051:
3049:
3046:
3044:
3041:
3039:
3036:
3034:
3031:
3029:
3026:
3024:
3021:
3019:
3016:
3014:
3011:
3009:
3006:
3004:
3001:
2999:
2996:
2994:
2991:
2990:
2989:
2985:
2981:
2978:
2977:
2975:
2971:
2963:
2960:
2958:
2955:
2953:
2950:
2948:
2945:
2943:
2940:
2938:
2935:
2933:
2930:
2928:
2925:
2923:
2920:
2918:
2915:
2913:
2910:
2908:
2905:
2904:
2903:
2900:
2899:
2897:
2893:
2885:
2882:
2880:
2877:
2875:
2872:
2870:
2867:
2865:
2862:
2860:
2857:
2855:
2852:
2850:
2847:
2845:
2842:
2840:
2837:
2835:
2832:
2831:
2830:
2827:
2826:
2824:
2820:
2812:
2809:
2807:
2804:
2803:
2802:
2798:
2797:
2795:
2791:
2783:
2780:
2778:
2775:
2773:
2770:
2768:
2765:
2763:
2760:
2758:
2755:
2753:
2750:
2748:
2745:
2743:
2740:
2738:
2735:
2733:
2730:
2728:
2725:
2723:
2720:
2718:
2715:
2714:
2713:
2710:
2709:
2707:
2703:
2695:
2692:
2690:
2687:
2685:
2682:
2680:
2677:
2675:
2672:
2670:
2667:
2665:
2662:
2661:
2660:
2657:
2656:
2654:
2650:
2646:
2639:
2635:
2631:
2624:
2620:
2615:
2611:
2608:
2604:
2600:
2593:
2588:
2586:
2581:
2579:
2574:
2573:
2570:
2563:
2559:
2556:
2553:
2549:
2546:
2543:
2539:
2536:
2535:
2531:
2522:
2518:
2513:
2508:
2504:
2500:
2497:(2): 626–34.
2496:
2492:
2488:
2481:
2478:
2473:
2469:
2465:
2461:
2457:
2453:
2446:
2443:
2438:
2434:
2430:
2426:
2422:
2418:
2410:
2407:
2402:
2398:
2394:
2390:
2386:
2382:
2375:
2372:
2367:
2363:
2359:
2355:
2351:
2347:
2340:
2337:
2332:
2328:
2324:
2320:
2316:
2312:
2308:
2304:
2300:
2296:
2289:
2286:
2281:
2277:
2272:
2267:
2264:(2): 967–78.
2263:
2259:
2255:
2248:
2245:
2240:
2236:
2231:
2226:
2223:(1): 237–55.
2222:
2218:
2214:
2207:
2204:
2199:
2195:
2191:
2187:
2183:
2179:
2175:
2171:
2164:
2161:
2156:
2152:
2148:
2144:
2140:
2136:
2132:
2128:
2121:
2118:
2113:
2109:
2104:
2099:
2095:
2091:
2088:(8): 528–35.
2087:
2083:
2079:
2072:
2069:
2064:
2060:
2055:
2050:
2046:
2042:
2038:
2034:
2030:
2023:
2021:
2017:
2012:
2008:
2003:
1998:
1993:
1988:
1984:
1980:
1976:
1972:
1968:
1961:
1959:
1955:
1949:
1946:
1941:
1937:
1932:
1927:
1923:
1919:
1915:
1911:
1907:
1903:
1899:
1892:
1889:
1884:
1880:
1875:
1870:
1866:
1862:
1858:
1851:
1848:
1843:
1839:
1835:
1831:
1826:
1821:
1817:
1813:
1809:
1802:
1799:
1794:
1790:
1786:
1782:
1777:
1772:
1769:(9): 1255–9.
1768:
1764:
1760:
1753:
1750:
1745:
1741:
1736:
1731:
1726:
1721:
1717:
1713:
1712:FASEB Journal
1709:
1694:
1692:
1688:
1683:
1679:
1675:
1671:
1667:
1663:
1656:
1654:
1650:
1645:
1641:
1636:
1631:
1626:
1621:
1618:(9): 4355–9.
1617:
1613:
1609:
1602:
1600:
1596:
1591:
1587:
1583:
1579:
1575:
1571:
1564:
1561:
1556:
1552:
1547:
1542:
1537:
1532:
1528:
1524:
1520:
1516:
1512:
1505:
1502:
1497:
1493:
1489:
1485:
1481:
1477:
1474:(2): 388–95.
1473:
1469:
1465:
1458:
1455:
1450:
1446:
1442:
1438:
1434:
1430:
1426:
1422:
1418:
1414:
1407:
1405:
1403:
1401:
1399:
1397:
1395:
1391:
1386:
1382:
1377:
1372:
1368:
1364:
1360:
1353:
1351:
1347:
1342:
1338:
1334:
1330:
1327:(8): 1991–7.
1326:
1322:
1314:
1311:
1306:
1302:
1297:
1292:
1288:
1284:
1280:
1276:
1272:
1265:
1262:
1257:
1251:
1247:
1240:
1238:
1236:
1234:
1230:
1225:
1221:
1216:
1211:
1206:
1201:
1197:
1193:
1189:
1182:
1179:
1174:
1170:
1165:
1160:
1156:
1152:
1148:
1141:
1139:
1135:
1130:
1126:
1122:
1118:
1114:
1110:
1103:
1101:
1099:
1097:
1093:
1086:
1082:
1079:
1077:
1074:
1072:
1069:
1068:
1064:
1062:
1059:
1055:
1051:
1050:
1045:
1040:
1038:
1034:
1029:
1021:
1019:
1018:
1014:
1009:
1002:
998:
994:
993:atractyloside
985:
978:
976:
974:
970:
966:
962:
958:
954:
950:
945:
937:
935:
934:
930:
924:
922:
918:
914:
910:
887:
886:
885:
882:
880:
876:
868:
866:
862:
859:
857:
853:
849:
845:
841:
836:
834:
829:
825:
817:
815:
813:
809:
805:
801:
797:
794:
793:transmembrane
789:
782:
778:
773:
765:
761:
754:
747:
742:
739:
737:
733:
730:
727:
724:
723:
722:
720:
716:
708:
706:
705:superfamily.
704:
700:
696:
692:
688:
684:
680:
676:
672:
667:
665:
661:
657:
653:
649:
645:
641:
637:
633:
629:
617:
614:
610:
607:
604:
600:
595:
591:
588:
587:
583:
580:
578:
574:
569:
566:
563:
561:
557:
554:
551:
549:
545:
542:
539:
537:
533:
530:
527:
525:
521:
518:
515:
513:
509:
505:
501:
498:
495:
491:
486:
481:
470:
467:
463:
460:
457:
453:
448:
444:
441:
440:
436:
433:
431:
427:
422:
419:
416:
414:
410:
407:
404:
402:
398:
395:
392:
390:
386:
383:
380:
378:
374:
371:
368:
366:
362:
358:
354:
350:
346:
341:
336:
325:
322:
318:
315:
312:
308:
303:
299:
296:
295:
291:
288:
286:
282:
277:
274:
271:
269:
265:
262:
259:
257:
253:
250:
247:
245:
241:
238:
235:
233:
229:
226:
223:
221:
217:
213:
209:
206:
203:
199:
194:
189:
178:
175:
173:
169:
166:
162:
158:
155:
153:
149:
145:
141:
138:
135:
131:
126:
122:
119:
116:
114:
110:
107:
104:
102:
98:
95:
92:
90:
86:
83:
80:
78:
74:
71:
68:
66:
62:
58:
54:
49:
43:
39:
32:
27:
22:
19:
5657:
4753:transporter
4706:transporter
3792:transporter
3603:transporter
2986:- dependent
2494:
2490:
2480:
2458:(3): 345–9.
2455:
2451:
2445:
2423:(1): 34–41.
2420:
2416:
2409:
2387:(1): 312–5.
2384:
2380:
2374:
2352:(1): 184–8.
2349:
2345:
2339:
2298:
2294:
2288:
2261:
2257:
2247:
2220:
2216:
2206:
2173:
2169:
2163:
2133:(1): 17–24.
2130:
2126:
2120:
2085:
2081:
2071:
2036:
2032:
1974:
1970:
1948:
1905:
1901:
1891:
1864:
1860:
1850:
1815:
1811:
1801:
1766:
1763:FEBS Letters
1762:
1752:
1715:
1711:
1665:
1661:
1635:11380/811305
1615:
1611:
1573:
1569:
1563:
1518:
1514:
1504:
1471:
1467:
1457:
1416:
1412:
1366:
1362:
1324:
1321:Biochemistry
1320:
1313:
1278:
1274:
1264:
1246:Biochemistry
1245:
1215:11563/126168
1195:
1191:
1181:
1154:
1150:
1112:
1108:
1053:
1047:
1041:
1037:mitochondria
1032:
1025:
990:
941:
925:
917:hydrogen ion
906:
883:
872:
863:
860:
837:
821:
790:
786:
780:
776:
712:
668:
647:
643:
639:
635:
631:
627:
626:
584:
503:Alt. symbols
437:
356:Alt. symbols
292:
211:Alt. symbols
18:
4613:zinc efflux
938:Alterations
879:nucleotides
736:fibroblasts
715:paraologous
606:Swiss-model
488:Identifiers
459:Swiss-model
343:Identifiers
314:Swiss-model
196:Identifiers
113:OPM protein
51:Identifiers
5674:Categories
5639:Cl-oxalate
5634:Cl-formate
5561:Na/glucose
4751:Acetyl-CoA
1087:References
995:(ATR) and
979:Inhibition
875:antiporter
828:hydrolysis
602:Structures
597:Search for
571:Other data
455:Structures
450:Search for
424:Other data
310:Structures
305:Search for
279:Other data
140:structures
94:2.A.29.1.2
5658:see also
5530:Symporter
5518:Ion pumps
1908:: 26700.
973:mutations
915:, or one
902:cytoplasm
890:cytoplasm
840:Magnesium
833:metabolic
800:substrate
796:α-helices
748:Structure
679:cytoplasm
553:NM_001636
512:NCBI gene
406:NM_001152
365:NCBI gene
261:NM_001151
220:NCBI gene
82:IPR002113
5627:(Band 3)
5611:Na/(Ca-K
5181:SLC41–48
5134:SLC39A14
5129:SLC39A13
5124:SLC39A12
5119:SLC39A11
5114:SLC39A10
5046:SLC38A10
4687:SLC31–40
4663:SLC30A10
4477:SLC26A11
4472:SLC26A10
4404:SLC25A46
4399:SLC25A45
4394:SLC25A44
4389:SLC25A43
4384:SLC25A42
4379:SLC25A41
4374:SLC25A40
4369:SLC25A39
4364:SLC25A38
4359:SLC25A37
4354:SLC25A36
4349:SLC25A35
4344:SLC25A34
4339:SLC25A33
4334:SLC25A32
4329:SLC25A31
4324:SLC25A30
4319:SLC25A29
4314:SLC25A28
4309:SLC25A27
4304:SLC25A26
4299:SLC25A25
4294:SLC25A24
4289:SLC25A23
4284:SLC25A22
4279:SLC25A21
4274:SLC25A20
4269:SLC25A19
4264:SLC25A18
4259:SLC25A17
4254:SLC25A16
4249:SLC25A15
4244:SLC25A14
4239:SLC25A13
4234:SLC25A12
4229:SLC25A11
4224:SLC25A10
4070:SLC22A20
4065:SLC22A19
4060:SLC22A18
4055:SLC22A17
4050:SLC22A16
4045:SLC22A15
4040:SLC22A14
4035:SLC22A13
4030:SLC22A12
4025:SLC22A11
4020:SLC22A10
3859:SLC21–30
3790:thiamine
3672:SLC16A14
3667:SLC16A13
3662:SLC16A12
3657:SLC16A11
3652:SLC16A10
3380:SLC11–20
2984:chloride
2627:By group
2323:14151375
2280:13549480
2239:14392158
2198:10926541
2155:36345010
2063:30611538
2011:24474793
1940:27221760
1834:21541983
1793:24773903
1785:21486564
1744:20207940
1590:20362544
1555:17566106
1488:17572439
1441:14603310
1385:12893834
1305:26468067
1224:26968366
1173:27001633
1129:18510943
1065:See also
1058:homology
818:Function
808:arginine
804:isoforms
767:)
719:isoforms
699:SLC25A31
666:family.
616:InterPro
469:InterPro
324:InterPro
157:RCSB PDB
77:InterPro
45:.
5542:Na/K,Cl
5456:SLCO1–4
5416:SLC47A2
5411:SLC47A1
5388:SLC46A2
5383:SLC46A1
5360:SLC45A4
5355:SLC54A3
5350:SLC45A2
5345:SLC45A1
5322:SLC44A5
5317:SLC44A4
5312:SLC44A3
5307:SLC44A2
5302:SLC44A1
5279:SLC43A3
5274:SLC43A2
5269:SLC43A1
5213:SLC41A3
5208:SLC41A2
5203:SLC41A1
5157:SLC40A1
5109:SLC39A9
5104:SLC39A8
5099:SLC39A7
5094:SLC39A6
5089:SLC39A5
5084:SLC39A4
5079:SLC39A3
5074:SLC39A2
5069:SLC39A1
5041:SLC38A6
5036:SLC38A5
5031:SLC38A4
5026:SLC38A3
5021:SLC38A2
5016:SLC38A1
4993:SLC37A4
4988:SLC37A3
4983:SLC37A2
4978:SLC37A1
4952:SLC36A4
4947:SLC36A3
4942:SLC36A2
4937:SLC36A1
4914:SLC35E4
4909:SLC35E3
4904:SLC35E2
4899:SLC35E1
4890:SLC35D3
4885:SLC35D2
4880:SLC35D1
4871:SLC35C2
4866:SLC35C1
4857:SLC35B4
4852:SLC35B3
4847:SLC35B2
4842:SLC35B1
4833:SLC35A5
4828:SLC35A4
4823:SLC35A3
4818:SLC35A2
4813:SLC35A1
4790:SLC34A3
4785:SLC34A2
4780:SLC34A1
4757:SLC33A1
4733:SLC32A1
4710:SLC31A1
4658:SLC30A9
4653:SLC30A8
4648:SLC30A7
4643:SLC30A6
4638:SLC30A5
4633:SLC30A4
4628:SLC30A3
4623:SLC30A2
4618:SLC30A1
4595:SLC29A4
4590:SLC29A3
4585:SLC29A2
4580:SLC29A1
4557:SLC28A3
4552:SLC28A2
4547:SLC28A1
4525:SLC27A6
4520:SLC27A5
4515:SLC27A4
4510:SLC27A3
4505:SLC27A2
4500:SLC27A1
4467:SLC26A9
4462:SLC26A8
4457:SLC26A7
4452:SLC26A6
4447:SLC26A5
4442:SLC26A4
4437:SLC26A3
4432:SLC26A2
4427:SLC26A1
4219:SLC25A9
4214:SLC25A8
4209:SLC25A7
4204:SLC25A6
4199:SLC25A5
4194:SLC25A4
4189:SLC25A3
4184:SLC25A2
4179:SLC25A1
4156:SLC24A6
4151:SLC24A5
4146:SLC24A4
4141:SLC24A3
4136:SLC24A2
4131:SLC24A1
4108:SLC23A4
4103:SLC23A3
4098:SLC23A2
4093:SLC23A1
4015:SLC22A9
4010:SLC22A8
4005:SLC22A7
4000:SLC22A6
3995:SLC22A5
3990:SLC22A4
3985:SLC22A3
3980:SLC22A2
3975:SLC22A1
3951:SLCO6A1
3947:SLCO5A1
3938:SLCO4C1
3933:SLCO4A1
3924:SLCO3A1
3915:SLCO2B1
3910:SLCO2A1
3901:SLCO1C1
3896:SLCO1B4
3891:SLCO1B3
3886:SLCO1B1
3881:SLCO1A2
3835:SLC20A2
3830:SLC20A1
3806:SLC19A3
3801:SLC19A2
3796:SLC19A1
3768:SLC18A3
3763:SLC18A2
3758:SLC18A1
3735:SLC17A9
3730:SLC17A8
3725:SLC17A7
3720:SLC17A6
3715:SLC17A5
3710:SLC17A4
3705:SLC17A3
3700:SLC17A2
3695:SLC17A1
3647:SLC16A9
3642:SLC16A8
3637:SLC16A7
3632:SLC16A6
3627:SLC16A5
3622:SLC16A4
3617:SLC16A3
3612:SLC16A2
3607:SLC16A1
3583:SLC15A4
3578:SLC15A3
3573:SLC15A2
3568:SLC15A1
3545:SLC14A2
3540:SLC14A1
3517:SLC13A5
3512:SLC13A4
3507:SLC13A3
3502:SLC13A2
3497:SLC13A1
3474:SLC12A9
3469:SLC12A8
3464:SLC12A7
3459:SLC12A6
3454:SLC12A5
3449:SLC12A4
3444:SLC12A3
3439:SLC12A2
3434:SLC12A1
3407:SLC11A2
3402:SLC11A1
3336:SLC10A7
3331:SLC10A6
3326:SLC10A5
3321:SLC10A4
3316:SLC10A3
3311:SLC10A2
3306:SLC10A1
3283:SLC9A11
3278:SLC9A10
3177:SLC7A14
3172:SLC7A13
3167:SLC7A11
3162:SLC7A10
3088:SLC6A20
3083:SLC6A19
3078:SLC6A18
3073:SLC6A17
3068:SLC6A16
3063:SLC6A15
3058:SLC6A14
3053:SLC6A13
3048:SLC6A12
3043:SLC6A11
3038:SLC6A10
2642:SLC1–10
2521:3023860
2472:7076130
2437:1259440
2401:5840415
2366:5857365
2331:4170544
2303:Bibcode
2178:Bibcode
2170:Science
2147:9443707
2112:3050098
2103:1080029
2054:6349463
2002:3910652
1979:Bibcode
1931:4879635
1910:Bibcode
1883:7961643
1842:6721812
1735:2887268
1682:8487299
1644:3031073
1546:1891095
1523:Bibcode
1496:6153793
1449:4338748
1421:Bibcode
1341:2990548
1296:4614496
1028:adenine
1022:History
969:introns
844:Calcium
741:SLC25A6
732:SLC25A5
726:SLC25A4
695:SLC25A6
691:SLC25A5
687:SLC25A4
677:to the
612:Domains
560:UniProt
497:SLC25A6
465:Domains
439:q24-q26
413:UniProt
351:SLC25A5
320:Domains
268:UniProt
205:SLC25A4
70:PF00153
4704:copper
3786:folate
3273:SLC9A9
3268:SLC9A8
3263:SLC9A7
3258:SLC9A6
3253:SLC9A5
3248:SLC9A4
3243:SLC9A3
3238:SLC9A2
3233:SLC9A1
3210:SLC8A3
3205:SLC8A2
3200:SLC8A1
3157:SLC7A9
3152:SLC7A8
3147:SLC7A7
3142:SLC7A6
3137:SLC7A5
3124:SLC7A4
3119:SLC7A3
3114:SLC7A2
3109:SLC7A1
3033:SLC6A9
3028:SLC6A8
3023:SLC6A7
3018:SLC6A6
3013:SLC6A5
3008:SLC6A4
3003:SLC6A3
2998:SLC6A2
2993:SLC6A1
2982:- and
2980:sodium
2907:SLC5A1
2834:SLC4A1
2806:SLC3A1
2717:SLC2A1
2664:SLC1A1
2564:(MeSH)
2554:(MeSH)
2544:(MeSH)
2519:
2512:367554
2509:
2470:
2435:
2399:
2364:
2329:
2321:
2295:Nature
2278:
2237:
2196:
2153:
2145:
2110:
2100:
2061:
2051:
2009:
1999:
1938:
1928:
1881:
1840:
1832:
1791:
1783:
1742:
1732:
1680:
1642:
1588:
1553:
1543:
1494:
1486:
1447:
1439:
1413:Nature
1383:
1339:
1303:
1293:
1252:
1222:
1171:
1127:
1054:et al.
1033:et al.
898:matrix
894:matrix
865:pore.
842:, non-
812:lysine
582:Chr. Y
565:P12236
548:RefSeq
541:403000
493:Symbol
435:Chr. X
418:P05141
401:RefSeq
394:300150
348:Symbol
290:Chr. 4
273:P12235
256:RefSeq
249:103220
201:Symbol
172:PDBsum
146:
136:
56:Symbol
5606:Na/Ca
5556:Na/Cl
5427:(48):
5399:(47):
5371:(46):
5333:(45):
5290:(44):
5257:(43):
5224:(42):
5191:(41):
5145:(40):
5057:(39):
5004:(38):
4966:(37):
4925:(36):
4801:(35):
4768:(34):
4744:(33):
4721:(32):
4697:(31):
4606:(30):
4568:(29):
4536:(28):
4488:(27):
4415:(26):
4167:(25):
4119:(24):
4081:(23):
3963:(22):
3869:(21):
3817:(20):
3779:(19):
3746:(18):
3683:(17):
3594:(16):
3556:(15):
3528:(14):
3485:(13):
3421:(12):
3390:(11):
3294:(10):
2614:TC 2A
2327:S2CID
2151:S2CID
1838:S2CID
1789:S2CID
1492:S2CID
1445:S2CID
900:+ ATP
896:→ ADP
892:+ ATP
709:Types
577:Locus
529:10992
430:Locus
382:10991
285:Locus
237:10990
5613:) -
5601:Na/H
5571:Cl/K
5566:Na/I
5547:Na/P
5491:O4A1
5486:O431
5481:O2B1
5476:O1B3
5471:O1B1
5466:O1A2
5246:RhCG
5241:RhBG
5236:RhAG
4955:36A2
3410:11A3
3358:10A7
3353:10A3
3348:10A2
3343:10A1
3221:(9):
3188:(8):
3099:(7):
2973:(6):
2895:(5):
2822:(4):
2793:(3):
2705:(2):
2652:(1):
2517:PMID
2468:PMID
2433:PMID
2397:PMID
2362:PMID
2319:PMID
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