288:
enucleations, pleomorphic adenomas of parotid gland were recommended to be routinely treated with superficial or total parotidectomy. These procedures combine complete tumor removal and identification of the main trunk of facial nerve during surgery to avoid any lesions to the nerve. However, extensive surgery may cause significant morbidity, such as Frey´s syndrome (excessive sweat while eating) and salivary fistula. Also, aesthetic outcome may be compromised. Therefore, less invasive procedures have been preferred in selected cases during the recent years, and introduction of perioperative neuromonitoring enabled the evolution of several different surgical techniques some twenty years ago.
141:, it can recur after resection, it invades normal adjacent tissue, and distant metastases have been reported after long (+10 years) time intervals. This tumour most often presents in the lower pole of the superficial lobe of the gland, about 10% of the tumours arise in the deeper portions of the gland. It occurs more frequently in females than in males, the ratio approximating 6:4. The majority of the lesion are found in patients in the fourth to sixth decades with an average age of occurrences of about 43 years, but these are relatively common in young adults and have been known to occur in children.
268:
161:
76:
260:
48:
150:
202:
292:
experience of surgeon plays a key role in the results of these distinct procedures. An important point of view is that recurrent pleomorphic adenomas may occur after a very long time from primary surgery, on average over 7–10 years but up to 24 years afterwards. Thus, it is of utmost importance to evaluate the ultimate results of these different surgical techniques in the future.
59:). It can usually be diagnosed by its typical fibrillary stroma (mesenchyme). Stromal cell nuclei are small. Myoepithelial cells are usually the predominant cell type, and their nuclei can have various shapes but are usually more elongated than in epithelial cells. Epithelial cell nuclei may have prominent nucleoli.
283:
Surgical treatment of parotid gland tumors is sometimes difficult, partly because of the anatomical relationship of the facial nerve and the parotid lodge, but also through the increased potential for postoperative relapse. Thus, detection of early stages of a tumor of the parotid gland is extremely
181:
that may be mucoid, myxoid, cartilaginous or hyaline. Epithelial elements may be arranged in duct-like structures, sheets, clumps and/or interlacing strands and consist of polygonal, spindle or stellate-shaped cells (hence pleiomorphism). Areas of squamous metaplasia and epithelial pearls may be
291:
Currently, the choice of surgical approach for parotid pleomorphic adenoma is mainly based on the size, location, and mobility of the tumor. The recommended main techniques include extracapsular dissection, partial superficial parotidectomy, and lateral or total parotidectomy. Nevertheless, the
287:
There have been several approaches for surgery of parotid pleomorphic adenoma in the course of time. Enucleation of the tumor (i.e. intracapsular dissection), a procedure that was common in the early 20th century, is nowadays obsolete due to very high incidence of recurrence. After the time of
314:
Malignant salivary tumors usually require wide local resection of the primary tumor. However, if complete resection cannot be achieved, adjuvant radiotherapy should be added to improve local control. This surgical treatment has many sequelae such as cranial nerve damage,
242:
In terms of imaging studies, ultrasound can determine and characterize superficial parotid tumors. Certain types of salivary gland tumors have certain sonographic characteristics on ultrasound. Ultrasound is also frequently used to guide FNA or core needle biopsy.
116:
The tumor is usually solitary and presents as a slow growing, painless, firm single nodular mass. Isolated nodules are generally outgrowths of the main nodule rather than a multinodular presentation. It is usually mobile unless found in the palate and can cause
702:
Schapher M, Koch M, Agaimy A, Goncalves M, Mantsopoulos K, Iro H (September 2019). "Parotid pleomorphic adenomas: Factors influencing surgical techniques, morbidity, and long-term outcome relative to the new ESGS classification in a retrospective study".
182:
present. The tumor is not enveloped, but it is surrounded by a fibrous pseudocapsule of varying thickness. The tumor extends through normal glandular parenchyma in the form of finger-like pseudopodia, but this is not a sign of malignant transformation.
246:
CT allows direct, bilateral visualization of the salivary gland tumor and provides information about overall dimension and tissue invasion. CT is excellent for demonstrating bony invasion. MRI provides superior soft tissue delineation such as
1191:
1176:
168:
Morphological diversity is the most characteristic feature of this neoplasm. Histologically, it is highly variable in appearance, even within individual tumors. Classically it is biphasic and is characterized by an admixture of polygonal
275:
Overall, the mainstay of the treatment for salivary gland tumor is surgical resection. Needle biopsy is highly recommended prior to surgery to confirm the diagnosis. More detailed surgical technique and the support for additional
92:) is a common benign salivary gland neoplasm characterised by neoplastic proliferation of epithelial (ductal) cells along with myoepithelial components, having a malignant potentiality. It is the most common type of
1966:
164:
Histopathology of pleomorphic adenoma (H&E stain). The stromal (also called mesenchymal) component often exhibits myxofibrous appearance and in some instances shows chondromatous differentiation.
572:
Koyuncu M, Seşen T, Akan H, Ismailoglu AA, Tanyeri Y, Tekat A, et al. (December 2003). "Comparison of computed tomography and magnetic resonance imaging in the diagnosis of parotid tumors".
213:(FNA) and core needle biopsy (bigger needle comparing to FNA). Both of these procedures can be done in an outpatient setting. Diagnostic imaging techniques for salivary gland tumors include
1288:
1823:
1122:
Terhaard CH, Lubsen H, Rasch CR, Levendag PC, Kaanders HH, Tjho-Heslinga RE, et al. (January 2005). "The role of radiotherapy in the treatment of malignant salivary gland tumors".
1206:
1959:
1843:
946:
Britt CJ, Stein AP, Gessert T, Pflum Z, Saha S, Hartig GK (February 2017). Eisele DW (ed.). "Factors influencing sialocele or salivary fistula formation postparotidectomy".
1952:
2177:
1281:
1274:
749:
Silvoniemi A, Pulkkinen J, Grénman R (November 2010). "Parotidectomy in the treatment of pleomorphic adenoma -- analysis of long-term results".
125:
when located in the parotid gland. When found in the parotid tail, it may present as an eversion of the ear lobe. Though it is classified as a
817:
2052:
1644:
1491:
322:
Usually about 44% of the patients have a complete histologic removal of the tumor and this refers to the most significant survival rate.
1327:
1214:
856:
Patey DH, Thackray AC (March 1958). "The treatment of parotid tumours in the light of a pathological study of parotidectomy material".
2047:
2172:
1404:
235:
Core needle biopsy can also be done in outpatient setting. It is more invasive but is more accurate compared to FNA with diagnostic
447:
Batsakis JG, Sneige N, el-Naggar AK (February 1992). "Fine-needle aspiration of salivary glands: its utility and tissue effects".
2057:
1895:
209:
The diagnosis of salivary gland tumors utilize both tissue sampling and radiographic studies. Tissue sampling procedures include
134:
228:
Fine needle aspiration biopsy (FNA), operated in experienced hands, can determine whether the tumor is malignant in nature with
1663:
1372:
137:, a risk that increases with time (9.5% chance to convert into malignancy in 15 years). Although it is "benign", the tumor is
1439:
1424:
1419:
108:
type", which refers to its dual origin from epithelial and myoepithelial elements as opposed to its pleomorphic appearance.
1537:
1444:
1838:
1828:
1549:
1486:
1038:
Leonetti JP, Marzo SJ, Petruzzelli GJ, Herr B (September 2005). "Recurrent pleomorphic adenoma of the parotid gland".
229:
1766:
1342:
222:
900:
267:
185:
The tumor often displays characteristic chromosomal translocations between chromosomes #3 and #8. This causes the
2167:
1890:
1778:
1559:
1944:
991:"Extracapsular dissection for clinically benign parotid lumps: reduced morbidity without oncological compromise"
387:
363:
2037:
2032:
1429:
1225:
1875:
2042:
2008:
1857:
1615:
1459:
1399:
1351:
101:
160:
1693:
1544:
1501:
1496:
259:
210:
47:
239:
greater than 97%. Furthermore, core needle biopsy allows more accurate histological typing of the tumor.
2027:
649:
Psychogios G, Bohr C, Constantinidis J, Canis M, Vander
Poorten V, Plzak J, et al. (January 2021).
651:"Review of surgical techniques and guide for decision making in the treatment of benign parotid tumors"
650:
2142:
1991:
1880:
1725:
1449:
1377:
812:
808:
93:
796:
533:"Role of ultrasonography in diagnosis and differentiation of pleomorphic adenomas: work in progress"
153:
75:
1796:
1678:
1478:
1454:
1414:
1409:
1322:
1195:
296:
248:
218:
804:
800:
1833:
1808:
1771:
1668:
1637:
1601:
1434:
1063:
971:
928:
881:
774:
728:
681:
597:
491:
472:
133:
have the capacity to grow to large proportions and may undergo malignant transformation, to form
2082:
331:
316:
1933:
1905:
1813:
1673:
1464:
1297:
1139:
1104:
1055:
1020:
963:
920:
873:
826:
766:
720:
673:
589:
554:
513:
464:
429:
304:
64:
1266:
263:
Relative incidence of parotid tumors, showing pleomorphic adenoma being a majority of tumors.
1762:
1658:
1596:
1532:
1131:
1094:
1047:
1010:
1002:
955:
912:
865:
758:
712:
665:
581:
544:
503:
456:
419:
122:
271:
Relative incidence of submandibular tumors, with pleomorphic adenoma being the most common.
1749:
1577:
792:
408:"Fine-needle aspiration biopsy of salivary gland lesions in a selected patient population"
186:
1885:
619:
1910:
1900:
1818:
1803:
1738:
1649:
1587:
1567:
1015:
990:
508:
105:
1200:
2161:
732:
685:
308:
232:
around 90%. FNA can also distinguish primary salivary tumor from metastatic disease.
174:
97:
1254:
1067:
885:
778:
601:
476:
17:
1928:
1572:
1474:
1391:
1364:
1332:
975:
932:
342:
300:
190:
178:
149:
126:
490:
Wan YL, Chan SC, Chen YL, Cheung YC, Lui KW, Wong HF, et al. (October 2004).
201:
104:(variable appearance) seen by light microscopy. It is also known as "Mixed tumor,
1230:
1135:
1051:
762:
585:
406:
Cohen EG, Patel SG, Lin O, Boyle JO, Kraus DH, Singh B, et al. (June 2004).
2129:
2124:
2116:
1999:
1983:
1920:
1758:
1632:
1627:
1527:
1301:
1099:
1082:
716:
669:
549:
532:
460:
424:
407:
193:. This activates the catenin pathway and leads to inappropriate cell division.
2102:
1865:
1714:
214:
170:
830:
1791:
1734:
1683:
1249:
1185:
869:
337:
299:
is treated by simple excision with preservation of mandibular branch of the
138:
56:
1143:
1108:
1059:
1024:
1006:
967:
924:
877:
770:
724:
677:
593:
558:
517:
433:
1081:
Ganly I, Patel SG, Coleman M, Ghossein R, Carlson D, Shah JP (July 2006).
468:
1975:
1304:
277:
236:
156:
specimen showing a well outlined solid neoplasm with cartilaginous areas.
69:
1168:
1987:
1387:
1360:
1308:
916:
130:
118:
959:
311:. Other benign tumors of minor salivary glands are treated similarly.
1623:
1523:
1515:
1180:
901:"Evolution and changing trends in surgery for benign parotid tumors"
899:
Mantsopoulos K, Koch M, Klintworth N, Zenk J, Iro H (January 2015).
396:
Last author update: 30 July 2021. Last staff update: 6 February 2023
372:
Last author update: 30 July 2021. Last staff update: 6 February 2023
492:"Ultrasonography-guided core-needle biopsy of parotid gland masses"
1710:
280:
radiotherapy depends on whether the tumor is malignant or benign.
200:
148:
1219:
834:
1948:
1270:
1979:
1124:
International
Journal of Radiation Oncology, Biology, Physics
531:
Białek EJ, Jakubowski W, Karpińska G (September 2003).
1824:
Multiple cutaneous and uterine leiomyomatosis syndrome
384:
Image by Mikael Häggström. Reference for description:
1083:"Malignant minor salivary gland tumors of the larynx"
1158:
2115:
2091:
2066:
2016:
2007:
1998:
1919:
1856:
1747:
1723:
1701:
1692:
1614:
1586:
1558:
1514:
1473:
1386:
1359:
1350:
1341:
1315:
1240:
1162:
63:
37:
32:
1087:Archives of Otolaryngology–Head & Neck Surgery
537:Archives of Otolaryngology–Head & Neck Surgery
412:Archives of Otolaryngology–Head & Neck Surgery
989:McGurk M, Thomas BL, Renehan AG (November 2003).
449:The Annals of Otology, Rhinology, and Laryngology
284:important in terms of prognosis after surgery.
1960:
1282:
100:. It derives its name from the architectural
8:
2013:
2004:
1967:
1953:
1945:
1698:
1356:
1347:
1289:
1275:
1267:
1159:
658:European Archives of Oto-Rhino-Laryngology
613:
611:
74:
46:
29:
1098:
1014:
548:
507:
423:
705:Journal of Cranio-Maxillo-Facial Surgery
496:AJNR. American Journal of Neuroradiology
266:
258:
159:
380:
378:
354:
189:gene to be juxtaposed to the gene for
55:Cytopathology of pleomorphic adenoma (
2053:Polymorphous low-grade adenocarcinoma
818:Rev. chir. oro-maxilo-fac. implantol.
744:
742:
697:
695:
7:
2178:Connective and soft tissue neoplasms
1040:Otolaryngology–Head and Neck Surgery
644:
642:
640:
638:
636:
574:Otolaryngology–Head and Neck Surgery
1328:Desmoplastic small-round-cell tumor
2048:Epithelial-myoepithelial carcinoma
846:(webpage has a translation button)
177:elements in a variable background
25:
1405:Aggressive infantile fibromatosis
205:Pleomorphic adenoma in ultrasound
96:and the most common tumor of the
2058:Hyalinizing clear cell carcinoma
1896:Clear-cell sarcoma of the kidney
813:"Parotid tumors: our experience"
135:carcinoma ex-pleomorphic adenoma
1664:Intradermal spindle cell lipoma
1373:Dermatofibrosarcoma protuberans
1492:Malignant fibrous histiocytoma
1440:Infantile digital fibromatosis
1425:Familial myxovascular fibromas
1420:Diffuse infantile fibromatosis
858:The British Journal of Surgery
1:
1538:Superficial acral fibromyxoma
1445:Juvenile hyaline fibromatosis
1839:Solitary cutaneous leiomyoma
1829:Multiple cutaneous leiomyoma
1550:Ossifying fibromyxoid tumour
1136:10.1016/j.ijrobp.2004.03.018
1052:10.1016/j.otohns.2005.04.008
763:10.3109/00016489.2010.488248
630:Diagrams by Mikael Häggström
586:10.1016/j.otohns.2003.07.009
2019:malignant epithelial tumors
1487:Benign fibrous histiocytoma
2194:
1767:Embryonal rhabdomyosarcoma
1343:Connective tissue neoplasm
1100:10.1001/archotol.132.7.767
717:10.1016/j.jcms.2019.06.009
670:10.1007/s00405-020-06250-x
620:"Salivary Gland Neoplasms"
550:10.1001/archotol.129.9.929
461:10.1177/000348949210100215
425:10.1001/archotol.130.6.773
319:, cosmetic problems, etc.
251:when compared to CT only.
223:magnetic resonance imaging
2138:
1891:Malignant rhabdoid tumour
1858:Complex mixed and stromal
1787:
1779:Alveolar rhabdomyosarcoma
995:British Journal of Cancer
295:The benign tumors of the
54:
45:
2173:Salivary gland neoplasia
2069:benign epithelial tumors
2038:Adenoid cystic carcinoma
2033:Mucoepidermoid carcinoma
1430:Fibroma of tendon sheath
2043:Salivary duct carcinoma
1460:Oral submucous fibrosis
1400:Aggressive fibromatosis
1316:Not otherwise specified
870:10.1002/bjs.18004519314
1502:Solitary fibrous tumor
1497:Atypical fibroxanthoma
1007:10.1038/sj.bjc.6601281
751:Acta Oto-Laryngologica
272:
264:
211:fine needle aspiration
206:
165:
157:
2028:Acinic cell carcinoma
1876:Mixed Müllerian tumor
628:Updated: Jan 13, 2021
388:"Pleomorphic adenoma"
364:"Pleomorphic adenoma"
334:- monomorphic adenoma
270:
262:
204:
163:
152:
112:Clinical presentation
1992:head and neck cancer
1881:Mesoblastic nephroma
1450:Plantar fibromatosis
1378:Desmoplastic fibroma
833:. 18. Archived from
94:salivary gland tumor
18:Adenoma, pleomorphic
2078:Pleomorphic adenoma
1871:Pleomorphic adenoma
1679:Spindle cell lipoma
1479:histiocytic sarcoma
1455:Pleomorphic fibroma
1415:Collagenous fibroma
1410:Aponeurotic fibroma
1323:Soft-tissue sarcoma
455:(2 Pt 1): 185–188.
297:submandibular gland
249:perineural invasion
219:computer tomography
173:and spindle-shaped
86:Pleomorphic adenoma
33:Pleomorphic adenoma
1834:Neural fibrolipoma
1809:Angiolipoleiomyoma
1772:Sarcoma botryoides
1669:Pleomorphic lipoma
1638:Myxoid liposarcoma
1602:Clear-cell sarcoma
1435:Fibromatosis colli
1241:External resources
917:10.1002/lary.24837
392:Pathology Outlines
368:Pathology Outlines
273:
265:
207:
166:
158:
90:benign mixed tumor
41:Benign mixed tumor
2155:
2154:
2151:
2150:
2111:
2110:
1942:
1941:
1934:Adenomatoid tumor
1906:Pancreatoblastoma
1852:
1851:
1814:Genital leiomyoma
1674:Lipoblastomatosis
1610:
1609:
1510:
1509:
1465:Pachydermodactyly
1264:
1263:
960:10.1002/hed.24564
757:(11): 1300–1305.
305:hypoglossal nerve
83:
82:
27:Medical condition
16:(Redirected from
2185:
2168:Benign neoplasms
2096:
2071:
2021:
2014:
2005:
1969:
1962:
1955:
1946:
1763:rhabdomyosarcoma
1752:
1728:
1704:
1699:
1659:Chondroid lipoma
1597:Synovial sarcoma
1533:Cutaneous myxoma
1357:
1348:
1291:
1284:
1277:
1268:
1160:
1148:
1147:
1119:
1113:
1112:
1102:
1078:
1072:
1071:
1035:
1029:
1028:
1018:
1001:(9): 1610–1613.
986:
980:
979:
943:
937:
936:
905:The Laryngoscope
896:
890:
889:
864:(193): 477–487.
853:
847:
845:
843:
842:
789:
783:
782:
746:
737:
736:
711:(9): 1356–1362.
699:
690:
689:
655:
646:
631:
627:
615:
606:
605:
569:
563:
562:
552:
528:
522:
521:
511:
502:(9): 1608–1612.
487:
481:
480:
444:
438:
437:
427:
403:
397:
395:
382:
373:
371:
359:
123:mandibular ramus
79:
78:
50:
30:
21:
2193:
2192:
2188:
2187:
2186:
2184:
2183:
2182:
2158:
2157:
2156:
2147:
2134:
2107:
2092:
2087:
2083:Warthin's tumor
2067:
2062:
2017:
1994:
1973:
1943:
1938:
1915:
1848:
1783:
1750:Skeletal muscle
1748:
1743:
1724:
1719:
1702:
1688:
1606:
1582:
1578:Phyllodes tumor
1560:Fibroepithelial
1554:
1506:
1469:
1382:
1337:
1311:
1295:
1265:
1260:
1259:
1236:
1235:
1171:
1157:
1152:
1151:
1121:
1120:
1116:
1080:
1079:
1075:
1037:
1036:
1032:
988:
987:
983:
948:Head & Neck
945:
944:
940:
898:
897:
893:
855:
854:
850:
840:
838:
821:(in Romanian).
809:Cristian Vlădan
793:Alexandru Bucur
791:
790:
786:
748:
747:
740:
701:
700:
693:
653:
648:
647:
634:
629:
617:
616:
609:
571:
570:
566:
530:
529:
525:
489:
488:
484:
446:
445:
441:
405:
404:
400:
385:
383:
376:
361:
360:
356:
351:
332:Warthin's tumor
328:
317:Frey's syndrome
257:
199:
147:
114:
73:
28:
23:
22:
15:
12:
11:
5:
2191:
2189:
2181:
2180:
2175:
2170:
2160:
2159:
2153:
2152:
2149:
2148:
2146:
2145:
2139:
2136:
2135:
2133:
2132:
2127:
2121:
2119:
2113:
2112:
2109:
2108:
2106:
2105:
2099:
2097:
2089:
2088:
2086:
2085:
2080:
2074:
2072:
2064:
2063:
2061:
2060:
2055:
2050:
2045:
2040:
2035:
2030:
2024:
2022:
2011:
2009:Salivary gland
2002:
1996:
1995:
1974:
1972:
1971:
1964:
1957:
1949:
1940:
1939:
1937:
1936:
1931:
1925:
1923:
1917:
1916:
1914:
1913:
1911:Carcinosarcoma
1908:
1903:
1901:Hepatoblastoma
1898:
1893:
1888:
1883:
1878:
1873:
1868:
1862:
1860:
1854:
1853:
1850:
1849:
1847:
1846:
1841:
1836:
1831:
1826:
1821:
1819:Leiomyosarcoma
1816:
1811:
1806:
1804:Angioleiomyoma
1801:
1800:
1799:
1788:
1785:
1784:
1782:
1781:
1776:
1775:
1774:
1755:
1753:
1745:
1744:
1742:
1741:
1739:leiomyosarcoma
1731:
1729:
1721:
1720:
1718:
1717:
1707:
1705:
1696:
1690:
1689:
1687:
1686:
1681:
1676:
1671:
1666:
1661:
1655:
1654:
1653:
1652:
1650:Angiomyolipoma
1642:
1641:
1640:
1635:
1620:
1618:
1612:
1611:
1608:
1607:
1605:
1604:
1599:
1593:
1591:
1584:
1583:
1581:
1580:
1575:
1570:
1568:Brenner tumour
1564:
1562:
1556:
1555:
1553:
1552:
1547:
1542:
1541:
1540:
1535:
1520:
1518:
1512:
1511:
1508:
1507:
1505:
1504:
1499:
1494:
1489:
1483:
1481:
1471:
1470:
1468:
1467:
1462:
1457:
1452:
1447:
1442:
1437:
1432:
1427:
1422:
1417:
1412:
1407:
1402:
1396:
1394:
1384:
1383:
1381:
1380:
1375:
1369:
1367:
1354:
1345:
1339:
1338:
1336:
1335:
1330:
1325:
1319:
1317:
1313:
1312:
1296:
1294:
1293:
1286:
1279:
1271:
1262:
1261:
1258:
1257:
1245:
1244:
1242:
1238:
1237:
1234:
1233:
1222:
1211:
1203:
1188:
1172:
1167:
1166:
1164:
1163:Classification
1156:
1155:External links
1153:
1150:
1149:
1130:(1): 103–111.
1114:
1093:(7): 767–770.
1073:
1046:(3): 319–322.
1030:
981:
954:(2): 387–391.
938:
911:(1): 122–127.
891:
848:
811:(March 2011).
797:Octavian Dincă
784:
738:
691:
632:
607:
580:(6): 726–732.
564:
543:(9): 929–933.
523:
482:
439:
418:(6): 773–778.
398:
374:
353:
352:
350:
347:
346:
345:
340:
335:
327:
324:
256:
253:
198:
195:
154:Sialadenectomy
146:
143:
129:, pleomorphic
113:
110:
106:salivary gland
81:
80:
67:
61:
60:
52:
51:
43:
42:
39:
35:
34:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
2190:
2179:
2176:
2174:
2171:
2169:
2166:
2165:
2163:
2144:
2141:
2140:
2137:
2131:
2128:
2126:
2123:
2122:
2120:
2118:
2114:
2104:
2101:
2100:
2098:
2095:
2090:
2084:
2081:
2079:
2076:
2075:
2073:
2070:
2065:
2059:
2056:
2054:
2051:
2049:
2046:
2044:
2041:
2039:
2036:
2034:
2031:
2029:
2026:
2025:
2023:
2020:
2015:
2012:
2010:
2006:
2003:
2001:
1997:
1993:
1989:
1985:
1981:
1977:
1970:
1965:
1963:
1958:
1956:
1951:
1950:
1947:
1935:
1932:
1930:
1927:
1926:
1924:
1922:
1918:
1912:
1909:
1907:
1904:
1902:
1899:
1897:
1894:
1892:
1889:
1887:
1884:
1882:
1879:
1877:
1874:
1872:
1869:
1867:
1864:
1863:
1861:
1859:
1855:
1845:
1842:
1840:
1837:
1835:
1832:
1830:
1827:
1825:
1822:
1820:
1817:
1815:
1812:
1810:
1807:
1805:
1802:
1798:
1795:
1794:
1793:
1790:
1789:
1786:
1780:
1777:
1773:
1770:
1769:
1768:
1764:
1760:
1757:
1756:
1754:
1751:
1746:
1740:
1736:
1733:
1732:
1730:
1727:
1726:Smooth muscle
1722:
1716:
1712:
1709:
1708:
1706:
1700:
1697:
1695:
1691:
1685:
1682:
1680:
1677:
1675:
1672:
1670:
1667:
1665:
1662:
1660:
1657:
1656:
1651:
1648:
1647:
1646:
1643:
1639:
1636:
1634:
1631:
1630:
1629:
1625:
1622:
1621:
1619:
1617:
1613:
1603:
1600:
1598:
1595:
1594:
1592:
1589:
1585:
1579:
1576:
1574:
1571:
1569:
1566:
1565:
1563:
1561:
1557:
1551:
1548:
1546:
1543:
1539:
1536:
1534:
1531:
1530:
1529:
1525:
1522:
1521:
1519:
1517:
1513:
1503:
1500:
1498:
1495:
1493:
1490:
1488:
1485:
1484:
1482:
1480:
1476:
1472:
1466:
1463:
1461:
1458:
1456:
1453:
1451:
1448:
1446:
1443:
1441:
1438:
1436:
1433:
1431:
1428:
1426:
1423:
1421:
1418:
1416:
1413:
1411:
1408:
1406:
1403:
1401:
1398:
1397:
1395:
1393:
1389:
1385:
1379:
1376:
1374:
1371:
1370:
1368:
1366:
1362:
1358:
1355:
1353:
1349:
1346:
1344:
1340:
1334:
1331:
1329:
1326:
1324:
1321:
1320:
1318:
1314:
1310:
1306:
1303:
1299:
1292:
1287:
1285:
1280:
1278:
1273:
1272:
1269:
1256:
1252:
1251:
1247:
1246:
1243:
1239:
1232:
1228:
1227:
1223:
1221:
1217:
1216:
1212:
1209:
1208:
1204:
1202:
1198:
1197:
1193:
1189:
1187:
1183:
1182:
1178:
1174:
1173:
1170:
1165:
1161:
1154:
1145:
1141:
1137:
1133:
1129:
1125:
1118:
1115:
1110:
1106:
1101:
1096:
1092:
1088:
1084:
1077:
1074:
1069:
1065:
1061:
1057:
1053:
1049:
1045:
1041:
1034:
1031:
1026:
1022:
1017:
1012:
1008:
1004:
1000:
996:
992:
985:
982:
977:
973:
969:
965:
961:
957:
953:
949:
942:
939:
934:
930:
926:
922:
918:
914:
910:
906:
902:
895:
892:
887:
883:
879:
875:
871:
867:
863:
859:
852:
849:
837:on 2013-01-13
836:
832:
828:
824:
820:
819:
814:
810:
806:
802:
798:
794:
788:
785:
780:
776:
772:
768:
764:
760:
756:
752:
745:
743:
739:
734:
730:
726:
722:
718:
714:
710:
706:
698:
696:
692:
687:
683:
679:
675:
671:
667:
663:
659:
652:
645:
643:
641:
639:
637:
633:
625:
621:
618:Steve C Lee.
614:
612:
608:
603:
599:
595:
591:
587:
583:
579:
575:
568:
565:
560:
556:
551:
546:
542:
538:
534:
527:
524:
519:
515:
510:
505:
501:
497:
493:
486:
483:
478:
474:
470:
466:
462:
458:
454:
450:
443:
440:
435:
431:
426:
421:
417:
413:
409:
402:
399:
393:
389:
381:
379:
375:
369:
365:
358:
355:
348:
344:
341:
339:
336:
333:
330:
329:
325:
323:
320:
318:
312:
310:
309:lingual nerve
306:
302:
298:
293:
289:
285:
281:
279:
269:
261:
254:
252:
250:
244:
240:
238:
233:
231:
226:
224:
220:
216:
212:
203:
196:
194:
192:
188:
183:
180:
176:
175:myoepithelial
172:
162:
155:
151:
144:
142:
140:
136:
132:
128:
124:
120:
111:
109:
107:
103:
99:
98:parotid gland
95:
91:
87:
77:
71:
68:
66:
62:
58:
53:
49:
44:
40:
36:
31:
19:
2093:
2077:
2068:
2018:
1929:Mesothelioma
1886:Wilms' tumor
1870:
1573:Fibroadenoma
1475:Histiocytoma
1392:fibromatosis
1365:fibrosarcoma
1333:Skin sarcoma
1248:
1224:
1213:
1205:
1190:
1175:
1127:
1123:
1117:
1090:
1086:
1076:
1043:
1039:
1033:
998:
994:
984:
951:
947:
941:
908:
904:
894:
861:
857:
851:
839:. Retrieved
835:the original
822:
816:
805:Cosmin Totan
801:Tiberiu Niță
787:
754:
750:
708:
704:
664:(1): 15–29.
661:
657:
623:
577:
573:
567:
540:
536:
526:
499:
495:
485:
452:
448:
442:
415:
411:
401:
391:
367:
357:
343:Sialadenitis
321:
313:
301:facial nerve
294:
290:
286:
282:
274:
245:
241:
234:
227:
208:
191:beta catenin
184:
167:
127:benign tumor
115:
102:Pleomorphism
89:
85:
84:
2130:Rhabdomyoma
2125:Leukoplakia
2000:Oral cancer
1984:oral cavity
1921:Mesothelial
1759:Rhabdomyoma
1633:Myelolipoma
1628:liposarcoma
1545:Angiomyxoma
1528:myxosarcoma
1352:Fibromatous
1302:soft tissue
230:sensitivity
38:Other names
2162:Categories
2143:Oropharynx
2103:Oncocytoma
1866:Adenomyoma
1715:myosarcoma
1616:Lipomatous
1516:Myxomatous
1298:Connective
841:2012-06-06
825:(1): 7–9.
349:References
307:, and the
215:ultrasound
171:epithelial
2094:ungrouped
1797:Cutaneous
1792:Leiomyoma
1735:Leiomyoma
1694:Myomatous
1684:Hibernoma
1255:radio/531
1250:eMedicine
831:2069-3850
733:198169972
686:220965351
338:Carcinoma
255:Treatment
221:(CT) and
197:Diagnosis
145:Histology
139:aneuploid
65:Specialty
57:Pap stain
1588:Synovial
1309:sarcomas
1210:: 8940/0
1144:15629600
1109:16847187
1068:38480631
1060:16143173
1025:14583757
968:27550745
925:25043324
886:24930522
878:13536351
779:20865807
771:20528201
725:31331850
678:32749609
624:Medscape
602:24528326
594:14663442
559:12975263
518:15502149
477:10583105
434:15210562
386:Bin Xu.
362:Bin Xu.
326:See also
278:adjuvant
237:accuracy
131:adenomas
70:Oncology
1988:pharynx
1703:General
1388:Fibroma
1361:Fibroma
1231:D008949
1016:2394403
976:3758029
933:1929744
509:7976420
469:1739267
225:(MRI).
121:of the
119:atrophy
2117:Tongue
1976:Tumors
1645:PEComa
1624:Lipoma
1524:Myxoma
1305:tumors
1220:181030
1142:
1107:
1066:
1058:
1023:
1013:
974:
966:
931:
923:
884:
876:
829:
777:
769:
731:
723:
684:
676:
600:
592:
557:
516:
506:
475:
467:
432:
303:, the
179:stroma
72:
1844:STUMP
1711:Myoma
1590:-like
1207:ICD-O
1201:210.2
1064:S2CID
972:S2CID
929:S2CID
882:S2CID
775:S2CID
729:S2CID
682:S2CID
654:(PDF)
598:S2CID
473:S2CID
1986:and
1307:and
1226:MeSH
1215:OMIM
1196:9-CM
1140:PMID
1105:PMID
1056:PMID
1021:PMID
964:PMID
921:PMID
874:PMID
827:ISSN
767:PMID
721:PMID
674:PMID
590:PMID
555:PMID
514:PMID
465:PMID
430:PMID
187:PLAG
88:(or
1980:lip
1978:of
1192:ICD
1186:D11
1177:ICD
1132:doi
1095:doi
1091:132
1048:doi
1044:133
1011:PMC
1003:doi
956:doi
913:doi
909:125
866:doi
759:doi
755:130
713:doi
666:doi
662:278
582:doi
578:129
545:doi
541:129
504:PMC
457:doi
453:101
420:doi
416:130
2164::
1990:/
1982:,
1765::
1253::
1229::
1218::
1199::
1184::
1181:10
1138:.
1128:61
1126:.
1103:.
1089:.
1085:.
1062:.
1054:.
1042:.
1019:.
1009:.
999:89
997:.
993:.
970:.
962:.
952:39
950:.
927:.
919:.
907:.
903:.
880:.
872:.
862:45
860:.
815:.
807:;
803:;
799:;
795:;
773:.
765:.
753:.
741:^
727:.
719:.
709:47
707:.
694:^
680:.
672:.
660:.
656:.
635:^
622:.
610:^
596:.
588:.
576:.
553:.
539:.
535:.
512:.
500:25
498:.
494:.
471:.
463:.
451:.
428:.
414:.
410:.
390:.
377:^
366:.
217:,
1968:e
1961:t
1954:v
1761:/
1737:/
1713:/
1626:/
1526:/
1477:/
1390:/
1363:/
1300:/
1290:e
1283:t
1276:v
1194:-
1179:-
1169:D
1146:.
1134::
1111:.
1097::
1070:.
1050::
1027:.
1005::
978:.
958::
935:.
915::
888:.
868::
844:.
823:2
781:.
761::
735:.
715::
688:.
668::
626:.
604:.
584::
561:.
547::
520:.
479:.
459::
436:.
422::
394:.
370:.
20:)
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
