Knowledge (XXG)

Adenosine

Source šŸ“

509: 486: 904: 4475: 47: 4487: 854:. The IV push is often followed with a flush of 10ā€“20 mL of normal saline. If this has no effect (i.e., no evidence of transient AV block), a dose of 12 mg can be given 1ā€“2 minutes after the first dose. When given to dilate the arteries, such as in a "stress test", the dosage is typically 0.14 mg/kg/min, administered for 4 or 6 minutes, depending on the protocol. 38: 1122:
activity. Researchers at Cornell University have recently shown adenosine receptors to be key in opening the blood-brain barrier (BBB). Mice dosed with adenosine have shown increased transport across the BBB of amyloid plaque antibodies and prodrugs associated with Parkinson's disease, Alzheimer's,
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structure and bind to some of the same receptors as adenosine. Methylxanthines act as competitive antagonists of adenosine and can blunt its pharmacological effects. Individuals taking large quantities of methylxanthines may require increased doses of adenosine.
1385:, finding it was as potent as minoxidil (in overall treatment outcomes) but with higher satisfaction rate with patients due to ā€œfaster prevention of hair loss and appearance of the newly grown hairsā€ (further trials were called for to clarify the findings). 2935:
Oura H, Iino M, Nakazawa Y, Tajima M, Ideta R, Nakaya Y, et al. (December 2008). "Adenosine increases anagen hair growth and thick hairs in Japanese women with female pattern hair loss: a pilot, double-blind, randomized, placebo-controlled trial".
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The administration of adenosine also reduces blood flow to coronary arteries past the occlusion. Other coronary arteries dilate when adenosine is administered while the segment past the occlusion is already maximally dilated, which is a process called
1350:'s stimulatory effects are credited primarily (although not entirely) to its capacity to block adenosine receptors, thereby reducing the inhibitory tonus of adenosine in the CNS. This reduction in adenosine activity leads to increased activity of the 1327:
has been shown in lab animals to drastically increase tissue repair and reconstruction. Topical administration of adenosine for use in wound-healing deficiencies and diabetes mellitus in humans is currently under clinical investigation.
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Miller-Patrick K, Vincent DL, Early RJ, Weems YS, Tanaka Y, Ashimine DT, et al. (1993). "Effects of the purine biosynthesis pathway inhibitors azaserine, hadacidin, and mycophenolic acid on the developing ovine corpus luteum".
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Faghihi G, Iraji F, Rajaee Harandi M, Nilforoushzadeh MA, Askari G (2013). "Comparison of the efficacy of topical minoxidil 5% and adenosine 0.75% solutions on male androgenetic alopecia and measuring patient satisfaction rate".
956:. Caffeine also increases cyclic AMP levels through nonselective inhibition of phosphodiesterase. "Caffeine has a three-dimensional structure similar to that of adenosine," which allows it to bind and block its receptors. 1178:, subsequently inhibiting Ca current. It also causes endothelial-dependent relaxation of smooth muscle as is found inside the artery walls. This causes dilation of the "normal" segments of arteries, i.e. where the 4524: 1023:
tissue), these concentrations are quickly elevated (600ā€“1,200 nM). Thus, in regard to stress or injury, the function of adenosine is primarily that of cytoprotection preventing tissue damage during instances of
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O'Keefe JH, Bateman TM, Silvestri R, Barnhart C (September 1992). "Safety and diagnostic accuracy of adenosine thallium-201 scintigraphy in patients unable to exercise and those with left bundle branch block".
2981:"Adenosine stimulates growth of dermal papilla and lengthens the anagen phase by increasing the cysteine level via fibroblast growth factors 2 and 7 in an organ culture of mouse vibrissae hair follicles" 800:), and do not involve the AV node as part of the re-entrant circuit, are not typically converted by adenosine. However, the ventricular response rate is temporarily slowed with adenosine in such cases. 7677: 4891: 3207:
Sato A, Terata K, Miura H, Toyama K, Loberiza FR, Hatoum OA, et al. (April 2005). "Mechanism of vasodilation to adenosine in coronary arterioles from patients with heart disease".
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Carter AJ, O'Connor WT, Carter MJ, Ungerstedt U (May 1995). "Caffeine enhances acetylcholine release in the hippocampus in vivo by a selective interaction with adenosine A1 receptors".
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The recommended dose may be increased in patients on theophylline since methylxanthines prevent binding of adenosine at receptor sites. The dose is often decreased in patients on
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Adenosine is an endogenous purine nucleoside that modulates many physiological processes. Cellular signaling by adenosine occurs through four known adenosine receptor subtypes (
636: 5741: 979:. This is being contested, and it is now considered a relative contraindication (however, selective adenosine antagonists are being investigated for use in treatment of asthma) 8356: 8361: 4510: 1186:. This feature allows physicians to use adenosine to test for blockages in the coronary arteries, by exaggerating the difference between the normal and abnormal segments. 7670: 1716:
Mitchell J, Lazarenko G (November 2008). "Wide QRS complex tachycardia. Diagnosis: Supraventricular tachycardia with aberrant conduction; intravenous (IV) adenosine".
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receptors produces a constellation of responses that in general can be classified as anti-inflammatory. Enzymatic production of adenosine can be anti-
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Extracellular adenosine concentrations from normal cells are approximately 300 nM; however, in response to cellular damage (e.g., in inflammatory or
5734: 4321: 6914: 4341: 5845: 4351: 4191: 7275: 7197: 7134: 5685: 2483: 2433: 2068: 1397:. Adenosine levels rise during periods of wakefulness and lowers during sleep. Higher adenosine levels correlate with a stronger feeling of 8346: 8106: 5560: 4346: 4163: 3467: 3123: 2588:"A 7-deaza-adenosine analog is a potent and selective inhibitor of hepatitis C virus replication with excellent pharmacokinetic properties" 1496: 1139: 815:
for a few seconds. This can be disconcerting to a normally conscious patient, and is associated with angina-like sensations in the chest.
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to raise and regulate adenosine levels in the body, for the intended promotion of consistent and sustained sleep in the long term.
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InChI=1S/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)/t4-,6-,7-,10-/m1/s1
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Adenosine has been shown to promote thickening of hair on people with thinning hair. A 2013 study compared topical adenosine with
8391: 8061: 4186: 4128: 4068: 1235: 850:. Due to adenosine's extremely short half-life, the IV line is started as proximal (near) to the heart as possible, such as the 7250: 4425: 4365: 4138: 3342: 243: 158: 1669:"Electrophysiologic effects of adenosine triphosphate and adenosine on the mammalian heart: clinical and experimental aspects" 8351: 7849: 5095: 4871: 4866: 4413: 4407: 3766: 1245: 770: 704: 6799: 6369: 6779: 2270:"The Good, the Bad and the Unknown of CD38 in the Metabolic Microenvironment and Immune Cell Functionality of Solid Tumors" 6939: 6929: 6904: 4490: 4395: 4378: 3436: 846:(SVT), the initial dose is 6 mg to 12 mg, depending on standing orders or provider preference, given as a rapid 7645: 6744: 6739: 5850: 5009: 4823: 4818: 4419: 4401: 4384: 4133: 3786: 3761: 3401: 1491: 843: 755: 385: 7054: 1971: 6909: 6809: 5702: 5047: 5042: 4838: 4478: 4061: 1075: 465: 6899: 5826: 6536: 2753:"Treating lung inflammation with agonists of the adenosine A2A receptor: promises, problems and potential solutions" 8381: 7117: 6954: 6754: 6354: 6007: 5062: 4958: 4953: 4848: 4843: 4833: 4780: 4103: 3335: 5072: 5330: 4973: 4925: 3854: 3541: 3472: 7147: 6359: 7759: 7749: 5463: 5409: 5326: 5268: 5215: 5160: 5156: 5067: 5057: 4800: 3791: 1194:. This leads to less blood reaching the ischemic tissue, which in turn produces the characteristic chest pain. 866: 766: 7009: 6784: 6541: 4968: 1174:, inhibiting adenylyl cyclase, reducing cAMP and so causing cell hyperpolarization by increasing K efflux via 334: 7707: 7550: 7500: 6919: 6349: 5939: 5869: 5761: 5690: 5441: 5413: 5029: 4987: 4940: 4828: 4775: 4770: 3904: 3796: 3462: 1214: 847: 116: 1840: 504: 7739: 7560: 7525: 7510: 7358: 6979: 6794: 6394: 6364: 6312: 6067: 5952: 5884: 5145: 5052: 5004: 4999: 4790: 4118: 3909: 3776: 3756: 3721: 3621: 1424: 1343: 1183: 1078:. The four receptor subtypes are further classified based on their ability to either stimulate or inhibit 1003: 996: 882: 700: 192: 7966: 7580: 6824: 3168:"Anandamide enhances extracellular levels of adenosine and induces sleep: an in vivo microdialysis study" 8386: 7864: 7605: 7575: 7555: 7535: 7505: 6804: 6774: 6384: 6344: 5864: 5767: 5571: 5528: 5019: 4963: 4920: 4915: 4785: 4459: 4230: 4203: 3899: 3816: 3431: 1382: 1304: 1167: 1163: 1010: 989: 945: 870: 804: 762: 325: 8006: 6764: 6334: 2692:
Nakav S, Chaimovitz C, Sufaro Y, Lewis EC, Shaked G, Czeiger D, et al. (May 2008). Bozza P (ed.).
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Warren TK, Wells J, Panchal RG, Stuthman KS, Garza NL, Van Tongeren SA, et al. (April 2014).
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Olsen DB, Eldrup AB, Bartholomew L, Bhat B, Bosserman MR, Ceccacci A, et al. (October 2004).
1871:"Transcriptional profiling of lung cell populations in idiopathic pulmonary arterial hypertension" 1307:
viruses. Such adenosine analogs are potentially clinically useful since they can be taken orally.
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Because of the effects of adenosine on AV node-dependent SVTs, adenosine is considered a class V
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and prevents lethality in infected animals, raising the possibility of a new treatment for this
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HaskĆ³ G, Cronstein BN (January 2004). "Adenosine: an endogenous regulator of innate immunity".
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Murillo-Rodriguez E, Blanco-Centurion C, Sanchez C, Piomelli D, Shiromani PJ (December 2003).
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that occurs widely in nature in the form of diverse derivatives. The molecule consists of an
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can leave cell intact or can be degraded to hypoxanthine, xanthine, and ultimately uric acid
174: 6984: 6949: 6663: 6626: 6556: 6374: 5889: 834:(nuclear stress test) in patients unable to undergo adequate stress testing with exercise. 394: 374: 7265: 6673: 6668: 6641: 6616: 6187: 6127: 5750: 5649: 5640: 5131: 4646: 4575: 3972: 1443: 1439: 1417: 1238:, allows adenosine to accumulate in the blood stream. This causes an increase in coronary 918: 699:), which are essential for all life on Earth. Its derivatives include the energy carriers 680: 202: 182: 1146:, unlike other agonists of this receptor, adenosine is unable to induce the secretion of 3291:
Morgan JM, McCormack DG, Griffiths MJ, Morgan CJ, Barnes PJ, Evans TW (September 1991).
2893: 2709: 2652: 2544: 508: 485: 289: 7744: 7696: 7352: 7255: 7215: 6177: 6132: 5696: 5545: 4762: 4712: 4707: 4628: 4220: 4182: 4171: 4034: 3652: 3595: 3560: 3426: 3142: 3074: 3050:"Adenosine, caffeine, and sleep-wake regulation: state of the science and perspectives" 3049: 2853: 2844: 2829:"Caffeine induces dopamine and glutamate release in the shell of the nucleus accumbens" 2828: 2777: 2752: 2728: 2693: 2669: 2636: 2563: 2528: 2394: 2369: 2345: 2320: 2296: 2269: 2245: 2218: 2159: 2134: 2110: 2085: 1897: 1870: 1272: 1239: 1225: 1191: 1147: 903: 828: 789: 729:) is the chemical group formed by removal of the 5ā€²-hydroxy (OH) group. It is found in 692: 64:
Adenocard; Adenocor; Adenic; Adenoco; Adeno-Jec; Adenoscan; Adenosin; Adrekar; Krenosin
2612: 2587: 1685: 1668: 1106:, which has been reported to mediate adenosine inhibition of Ca conductance, whereas A 8340: 7655: 7342: 6499: 6257: 6192: 6022: 4881: 4876: 4795: 4727: 4666: 4148: 4025: 3952: 3667: 3396: 2949: 2912: 2877: 2751:
Trevethick MA, Mantell SJ, Stuart EF, Barnard A, Wright KN, Yeadon M (October 2008).
2603: 2045: 1818: 1119: 953: 808: 497: 2965: 1702: 1618: 1361:. Experimental evidence suggests that adenosine and adenosine agonists can activate 8228: 7961: 7779: 7625: 7565: 7462: 7447: 7442: 7421: 7369: 7347: 7260: 7230: 7187: 6728: 6262: 6172: 6117: 6107: 5580: 5467: 5194: 5174: 5122: 4722: 4565: 4533: 4143: 4006: 3986: 3841: 3708: 3631: 3533: 2527:
Yin Z, Chen YL, Schul W, Wang QY, Gu F, Duraiswamy J, et al. (December 2009).
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Solinas M, FerrƩ S, You ZB, Karcz-Kubicha M, Popoli P, Goldberg SR (August 2002).
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Saygin D, Tabib T, Bittar HE, Valenzi E, Sembrat J, Chan SY, et al. (2005).
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Hwang KA, Hwang YL, Lee MH, Kim NR, Roh SS, Lee Y, et al. (February 2012).
2422:"Role of the Growth Hormone Secretagogue Receptor in the Central Nervous System" 2370:"Adenosine receptor signaling modulates permeability of the blood-brain barrier" 1462: 1447: 1334:'s anti-inflammatory effect may be due to its stimulation of adenosine release. 1291:. The 7-deaza-adenosine analog has been shown to inhibit the replication of the 1179: 1159: 930: 738: 734: 5087: 2882:
Proceedings of the National Academy of Sciences of the United States of America
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Proceedings of the National Academy of Sciences of the United States of America
2135:"Adenosine receptors: therapeutic aspects for inflammatory and immune diseases" 2016:
Faudone G, Arifi S, Merk D (June 2021). "The Medicinal Chemistry of Caffeine".
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DelacrƩtaz E (March 2006). "Clinical practice. Supraventricular tachycardia".
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Certain SVTs can be successfully terminated with adenosine. This includes any
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Butler P, KrƤutler B (2006). "Biological Organometallic Chemistry of B12".
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It also plays a role in regulation of blood flow to various organs through
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Sek K, MĆølck C, Stewart GD, Kats L, Darcy PK, Beavis PA (December 2018).
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by terminating its RNA chain synthesis. This interaction suppresses peak
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potentiates the action of adenosine, requiring the use of lower doses.
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to induce sleep in conditions where sleep may be severely attenuated.
1405:(CBT-I), which is considered one of the most effective treatments for 8171: 7595: 7590: 7302: 6509: 6504: 6469: 6197: 5369: 4587: 4550: 4153: 4053: 3518: 3446: 1524: 972: 934: 672: 445: 3327: 2800:
Cronstein B (2010). "How does methotrexate suppress inflammation?".
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has been reported to directly inhibit the recombinant RNA-dependent
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an abnormal rhythm, it is normal for the heart to enter ventricular
37: 1519:. Topics in Organometallic Chemistry. Vol. 17. pp. 1ā€“55. 414: 7059: 6621: 6561: 3740: 3546: 3252:"Role of nitric oxide in adenosine-induced vasodilation in humans" 2450:"ŠŠ“ŠµŠ½Š¾Š·ŠøŠ½ Š² ŠŗŠ¾ŃŠ¼ŠµŃ‚ŠøŠŗŠµ - ŠŸŠ¾Š»ŃŒŠ·Š° Š°Š½Ń‚ŠøŠ²Š¾Š·Ń€Š°ŃŃ‚Š½Š¾Š¹ ŠŗŠ¾Ń€ŠµŠ¹ŃŠŗŠ¾Š¹ ŠŗŠ¾ŃŠ¼ŠµŃ‚ŠøŠŗŠø" 1431: 1158:
When it is administered intravenously, adenosine causes transient
902: 758:(SVT), adenosine is used to help identify and convert the rhythm. 577: 568: 425: 2368:
Carman AJ, Mills JH, Krenz A, Kim DG, Bynoe MS (September 2011).
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phosphorylation through a mechanism that requires the adenosine A
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American Journal of Physiology. Heart and Circulatory Physiology
2219:"Targeting Adenosine Receptor Signaling in Cancer Immunotherapy" 1573:
Borea PA, Gessi S, Merighi S, Vincenzi F, Varani K (July 2018).
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multiple sclerosis, and cancers of the central nervous system.
3293:"Adenosine as a vasodilator in primary pulmonary hypertension" 2426:
Brain Somatic Cross-Talk and the Central Control of Metabolism
1435: 696: 688: 7276: 7198: 7135: 1098:, which stimulates adenylate cyclase activity. In addition, A 1220:
When adenosine enters the circulation, it is broken down by
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HaskĆ³ G, Linden J, Cronstein B, Pacher P (September 2008).
1575:"Pharmacology of Adenosine Receptors: The State of the Art" 1323:
receptor. Topical treatment of adenosine to foot wounds in
711:. Adenosine is used as an intravenous medication for some 7865: 1991:
The Journal of Pharmacology and Experimental Therapeutics
8027: 2424:. In Kordon C, Robinson I, Hanoune J, Dantzer R (eds.). 207:
Rapidly converted to inosine and adenosine monophosphate
2428:. Springer Science & Business Media. pp. 42ā€“. 643: 220:
cleared plasma <30 seconds; half-life <10 seconds
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Rapidly cleared from circulation via enzyme degradation
109:(adenosine may be safe to the fetus in pregnant women) 7850: 1342:
In general, adenosine has an inhibitory effect in the
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Antonioli L, Pacher P, Vizi ES, HaskĆ³ G (June 2013).
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Perlis M, Shaw PJ, Cano G, Espie CA (January 2011).
2063:(2 ed.). Macmillan Learning. pp. 102ā€“103. 8308: 8107: 8105: 8025: 7863: 7706: 7480: 7430: 7318: 7301: 7274: 7196: 7133: 7116: 6727: 6306: 6291: 5808: 5777: 5760: 5648: 5639: 5602: 5559: 5527: 5457: 5440: 5403: 5320: 5266: 5213: 5154: 5139: 5130: 4986: 4904: 4857: 4809: 4761: 4750: 4698: 4627: 4618: 4541: 4447: 4360: 4302: 4251: 4162: 4091: 3999: 3965: 3945: 3938: 3926: 3889: 3882: 3872: 3840: 3749: 3739: 3707: 3687: 3609: 3568: 3559: 3532: 3481: 3455: 3384: 3375: 3365: 2529:"An adenosine nucleoside inhibitor of dengue virus" 2268:Konen JM, Fradette JJ, Gibbons DL (December 2019). 1393:Adenosine is a key factor in regulating the body's 1217:(AMP), though it is possible other pathways exist. 780:Fast rhythms of the heart that are confined to the 566: 553: 520: 515: 496: 464: 444: 424: 404: 384: 364: 344: 333: 324: 299: 279: 234: 224: 211: 201: 191: 181: 173: 157: 152: 127: 115: 94: 76: 68: 58: 53: 5846:4'-O-Ī²-D-Glucosyl-9-O-(6''-deoxysaccharosyl)olivil 7760:Placental growth hormone (growth hormone variant) 3048:Reichert CF, Deboer T, Landolt HP (August 2022). 952:, which enhances release of the neurotransmitter 765:that require the AV node for the re-entry, e.g., 842:When given for the evaluation or treatment of a 313: 4312:International Federation for Emergency Medicine 2059:Hillis DM, Sadava D, Hill RW, Price MV (2015). 1974:. R&S Pharmchem. April 2011. Archived from 1442:. These components also significantly increase 1401:, also known as sleep drive or sleep pressure. 288: 6313: 4316:International Conference on Emergency Medicine 1754:. Treasure Island, FL: StatPearls Publishing. 1552:(4th ed.). New York: W. H. Freeman. 271:-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol 7671: 7281:Tooltip Plasma membrane monoamine transporter 7203:Tooltip Equilibrative nucleoside transporters 7140:Tooltip Concentrative nucleoside transporters 5735: 5103: 4518: 4069: 3343: 1746:Goyal A, Basit H, Bhyan P, Zeltser R (2022). 1673:Journal of the American College of Cardiology 944:acts by blocking binding of adenosine to the 8: 4332:Canadian Association of Emergency Physicians 2321:"CD39 and CD73 in immunity and inflammation" 1741: 1739: 1140:ghrelin/growth hormone secretagogue receptor 1127:Ghrelin/growth hormone secretagogue receptor 777:can sometimes be terminated with adenosine. 28: 4438:Care of the Critically Ill Surgical Patient 4327:Australasian College for Emergency Medicine 2985:International Journal of Molecular Medicine 2478:(12th ed.). McGraw Hill. p. 245. 2223:International Journal of Molecular Sciences 166:In general: ā„ž (Prescription only) 8357:Chemical substances for emergency medicine 7678: 7664: 7656: 7315: 7130: 6303: 5774: 5742: 5728: 5720: 5645: 5454: 5151: 5136: 5110: 5096: 5088: 4992: 4908: 4758: 4624: 4525: 4511: 4503: 4076: 4062: 4054: 3996: 3962: 3942: 3933: 3886: 3879: 3846: 3746: 3713: 3565: 3381: 3372: 3350: 3336: 3328: 1182:is not separated from the tunica media by 507: 484: 373: 45: 36: 8362:Drugs acting on the cardiovascular system 3308: 3267: 3183: 3131:Principles and Practice of Sleep Medicine 3073: 2996: 2911: 2901: 2852: 2776: 2727: 2717: 2668: 2611: 2562: 2552: 2393: 2344: 2295: 2285: 2244: 2234: 2158: 2109: 2084:Brown RA, Spina D, Page CP (March 2008). 1947: 1937: 1896: 1886: 1684: 1600: 1590: 1403:Cognitive behavioral therapy for insomnia 393: 7320: 4322:American College of Emergency Physicians 1142:. However, while it is able to increase 4342:European Society for Emergency Medicine 1507: 1032:, and seizure activity. Activation of A 975:, traditionally considered an absolute 617: 597: 480: 353: 248: 7855:Tooltip Growth hormone-binding protein 7708: 7687: 4352:American Academy of Emergency Medicine 2802:Clinical and Experimental Rheumatology 2420:Smith RG, Betancourt L, Sun Y (2012). 1457:. These findings identify a potential 1438:by increasing adenosine levels in the 1248:is a known cause of immunodeficiency. 701:adenosine mono-, di-, and triphosphate 498: 27: 2592:Antimicrobial Agents and Chemotherapy 1667:Belhassen B, Pelleg A (August 1984). 1090:and decrease cAMP levels, while the A 910:'s principal mode of action is as an 453: 433: 86: 7: 4347:Asian Society for Emergency Medicine 1497:List of growth hormone secretagogues 914:of adenosine receptors in the brain. 140: 4432:Advanced Life Support in Obstetrics 4337:Royal College of Emergency Medicine 1634:The New England Journal of Medicine 823:Adenosine is used as an adjunct to 798:monomorphic ventricular tachycardia 413: 304: 6702:Tetramethylpyrazine (ligustrazine) 3143:10.1016/B978-1-4160-6645-3.00078-5 2845:10.1523/JNEUROSCI.22-15-06321.2002 1058:All adenosine receptor subtypes (A 881:, and/or chronic liver disease or 72:SR-96225 (developmental code name) 14: 3250:Costa F, Biaggioni I (May 1998). 3023:Acta Dermatovenerologica Croatica 2502:The Chinese Journal of Physiology 2476:Basic & Clinical Pharmacology 1920:Ribeiro JA, SebastiĆ£o AM (2010). 832:myocardial perfusion scintigraphy 4485: 4474: 4473: 4129:International emergency medicine 2950:10.1111/j.1346-8138.2008.00564.x 2604:10.1128/AAC.48.10.3944-3953.2004 2086:"Adenosine receptors and asthma" 1236:adenosine nucleoside transporter 1150:and increase its plasma levels. 538: 532: 4486: 4426:Pediatric Advanced Life Support 4139:Pre-hospital emergency medicine 2757:British Journal of Pharmacology 2090:British Journal of Pharmacology 1315:Adenosine is believed to be an 1094:adenosine receptors couple to G 683:. Adenosine is one of the four 625:Key:OIRDTQYFTABQOQ-KQYNXXCUSA-N 7800:Somatrogon (MOD-4023; hGH-CTP) 6318:Tooltip Adenosine triphosphate 4414:Acute Care of at-Risk Newborns 4408:Neonatal Resuscitation Program 3596:Norepinephrine (noradrenaline) 2876:Lee FS, Chao MV (March 2001). 2386:10.1523/JNEUROSCI.3337-11.2011 2139:Nature Reviews. Drug Discovery 2018:Journal of Medicinal Chemistry 1926:Journal of Alzheimer's Disease 1779:Pijls NH, De Bruyne B (2000). 1246:Adenosine deaminase deficiency 771:AV nodal reentrant tachycardia 705:Cyclic adenosine monophosphate 544: 526: 1: 7646:Receptor/signaling modulators 6008:8-Phenyl-1,3-dipropylxanthine 4396:Advanced cardiac life support 4379:Cardiopulmonary resuscitation 3137:(1). Elsevier Inc.: 850ā€“865. 1686:10.1016/S0735-1097(84)80233-8 703:, also known as AMP/ADP/ATP. 600:n2c1c(ncnc1n(c2)3O((O)3O)CO)N 4420:Pediatric basic life support 4402:Advanced trauma life support 4385:Mouth-to-mouth resuscitation 4134:Pediatric emergency medicine 2719:10.1371/journal.pone.0002107 2337:10.1016/j.molmed.2013.03.005 2325:Trends in Molecular Medicine 2030:10.1021/acs.jmedchem.1c00261 1819:10.1016/0002-8703(92)90268-z 1492:Adenosine reuptake inhibitor 1421:delta-9-tetrahydrocannabinol 1311:Anti-inflammatory properties 844:supraventricular tachycardia 807:. When adenosine is used to 756:supraventricular tachycardia 750:Supraventricular tachycardia 8347:Adenosine receptor agonists 7837:Antisense oligonucleotides: 3221:10.1152/ajpheart.00575.2004 2833:The Journal of Neuroscience 2374:The Journal of Neuroscience 1517:Bioorganometallic Chemistry 1176:inward rectifier K channels 1166:. This is mediated via the 1076:G-protein-coupled receptors 933:found in chocolate) have a 8408: 7148:6-Hydroxy-7-methoxyflavone 5855:-ethylcarboxamidoadenosine 4755:(Nucleoside monophosphate) 4104:Emergency medical services 2938:The Journal of Dermatology 1592:10.1152/physrev.00049.2017 1550:Principles of Biochemistry 1548:Nelson DL, Cox MM (2005). 1260: 1164:atrioventricular (AV) node 1114:receptors also couple to G 1051: 737:) and as a radical in the 516:Chemical and physical data 20: 8367:Ghrelin receptor agonists 7639: 5680: 5038: 4995: 4949: 4911: 4610:Unnatural base pair (UBP) 4468: 3849: 3716: 3402:Glutamic acid (glutamate) 3397:Aspartic acid (aspartate) 3054:Journal of Sleep Research 1416:A principal component of 633: 608: 588: 239: 44: 35: 7750:Human placental lactogen 7325:Tooltip Xanthine oxidase 4279:Epinephrine / Adrenaline 3586:Epinephrine (adrenaline) 3310:10.1161/01.CIR.84.3.1145 3269:10.1161/01.HYP.31.5.1061 2456:(in Russian). 2021-03-18 2196:10.1016/j.it.2003.11.003 1922:"Caffeine and adenosine" 867:congestive heart failure 767:AV reentrant tachycardia 21:Not to be confused with 8392:Hydroxymethyl compounds 6915:UDP-N-acetylglucosamine 4988:Nucleoside triphosphate 2808:(5 Suppl 61): S21ā€“S23. 2554:10.1073/pnas.0907010106 1215:adenosine monophosphate 984:Pharmacological effects 707:(cAMP) is pervasive in 695:is a building block of 8142:Examorelin (hexarelin) 7359:Cinnamomum osmophloeum 6068:Choline theophyllinate 4941:Xanthosine diphosphate 4905:Nucleoside diphosphate 4021:Carbonyl sulfide (COS) 3622:N-Methylphenethylamine 3185:10.1093/sleep/26.8.943 2903:10.1073/pnas.061020198 2096:(Suppl 1): S446ā€“S456. 1807:American Heart Journal 1409:, utilizes short-term 1344:central nervous system 1338:Central nervous system 1299:is protective against 1224:, which is present in 1184:atherosclerotic plaque 968:for adenosine include 915: 883:chronic kidney disease 773:(AVNRT). In addition, 763:re-entrant arrhythmias 8352:Antiarrhythmic agents 6602:Opiranserin (VVZ-149) 5943:-Cyclopentyladenosine 5572:muscarinic antagonist 5119:Antiarrhythmic agents 4460:Injury Severity Score 4231:Nasopharyngeal airway 4204:Intraosseous infusion 3762:2-AGE (noladin ether) 3098:"Adenosine and Sleep" 2998:10.3892/ijmm.2011.817 1939:10.3233/JAD-2010-1379 1875:Pulmonary Circulation 1579:Physiological Reviews 1383:androgenetic alopecia 1267:The adenosine analog 1228:and the vessel wall. 1206:can be the result of 1102:receptors couple to G 1086:receptors couple to G 906: 871:myocardial infarction 8197:Pralmorelin (GHRP-2) 7740:Eftansomatropin alfa 7401:Pistacia integerrima 6707:Ligusticum wallichii 6685:Ligusticum wallichii 6013:8-Phenyltheophylline 6003:8-Chlorotheophylline 5953:Neladenoson dalanate 4237:Oropharyngeal airway 4114:Emergency psychiatry 4099:Emergency department 3973:Carbon monoxide (CO) 3124:"Models of insomnia" 2769:10.1038/bjp.2008.329 2287:10.3390/cells9010052 2236:10.3390/ijms19123837 2184:Trends in Immunology 1888:10.1192/apt.11.6.432 1748:"Reentry Arrhythmia" 1646:10.1056/NEJMcp051145 1202:Adenosine used as a 805:antiarrhythmic agent 754:In individuals with 691:(and its derivative 8239:Ibutamoren (MK-677) 8067:Modified GRF (1-29) 7967:Somatostatin (1-28) 7962:Somatostatin (GHIH) 7730:Bovine somatotropin 5414:Ca channel blockers 5146:Na channel blockers 4811:Deoxyribonucleotide 4700:Deoxyribonucleoside 4603:Pyrimidine analogue 4216:Tracheal intubation 4210:Intravenous therapy 3978:Hydrogen sulfide (H 3832:Virodhamine (O-AEA) 2894:2001PNAS...98.3555L 2710:2008PLoSO...3.2107N 2661:10.1038/nature13027 2653:2014Natur.508..402W 2545:2009PNAS..10620435Y 2539:(48): 20435ā€“20439. 2380:(37): 13272ā€“13280. 2102:10.1038/bjp.2008.22 1263:Nucleoside analogue 1222:adenosine deaminase 1211:purine biosynthesis 1154:Mechanism of action 1048:Adenosine receptors 848:parenteral infusion 819:Nuclear stress test 786:atrial fibrillation 733:(an active form of 713:cardiac arrhythmias 709:signal transduction 687:building blocks of 32: 5707:Never to phase III 5590:muscarinic agonist 5331:K channel blockers 4390:Basic life support 4294:Sodium bicarbonate 4092:Emergency medicine 4085:Emergency medicine 4035:Sulfur dioxide (SO 3946:Cholinergic system 3648:Phenylethanolamine 3627:N-Methyltryptamine 3591:NAS (normelatonin) 3378:inhibitory systems 3376:Major excitatory / 3215:(4): H1633ā€“H1640. 2474:Katzung B (2012). 2061:Principles of Life 1932:(Suppl 1): S3-15. 1487:Adenosine receptor 1234:, an inhibitor of 1054:Adenosine receptor 916: 829:technetium (Tc99m) 775:atrial tachycardia 8382:Neurotransmitters 8334: 8333: 8316: 8289: 8113: 8033: 8007:Cyclosomatostatin 7871: 7847:Binding proteins: 7755:Lonapegsomatropin 7714: 7653: 7652: 7476: 7475: 7453:Mycophenolic acid 7312: 7297: 7296: 7127: 7112: 7111: 7108: 7107: 6679:Angelica sinensis 5771: 5717: 5716: 5676: 5675: 5635: 5634: 5436: 5435: 5316: 5315: 5085: 5084: 5081: 5080: 4982: 4981: 4900: 4899: 4859:Cyclic nucleotide 4746: 4745: 4500: 4499: 4289:Magnesium sulfate 4198:Electrocardiogram 4124:Medical emergency 4109:Emergency nursing 4051: 4050: 4047: 4046: 3995: 3994: 3987:Nitric oxide (NO) 3961: 3960: 3934: 3922: 3921: 3918: 3917: 3868: 3867: 3864: 3863: 3735: 3734: 3731: 3730: 3703: 3702: 3617:3-Iodothyronamine 3555: 3554: 3359:Neurotransmitters 3066:10.1111/jsr.13597 2839:(15): 6321ā€“6324. 2647:(7496): 402ā€“405. 2598:(10): 3944ā€“3953. 2485:978-0-07-176402-5 2435:978-3-642-18999-9 2070:978-1-4641-8652-3 2024:(11): 7156ā€“7178. 1841:"2014 Guidelines" 1781:Coronary Pressure 1724:(6): 572ā€“3, 581. 1640:(10): 1039ā€“1051. 1411:sleep deprivation 1352:neurotransmitters 1325:diabetes mellitus 1317:anti-inflammatory 1293:hepatitis C virus 1080:adenylate cyclase 1042:immunosuppressive 966:contraindications 960:Contraindications 929:found in tea, or 925:found in coffee, 893:Drug interactions 861:(Persantine) and 852:antecubital fossa 731:adenosylcobalamin 651: 650: 579:Interactive image 466:CompTox Dashboard 16:Chemical compound 8399: 8314: 8312: 8287: 8111: 8109: 8031: 8029: 7869: 7867: 7856: 7852: 7785:Somatropin pegol 7712: 7710: 7693: 7689: 7680: 7673: 7666: 7657: 7326: 7322: 7316: 7306: 7282: 7278: 7204: 7200: 7141: 7137: 7131: 7121: 6515:Rheum officinale 6319: 6315: 6304: 6048:Caffeine citrate 5998:7-Methylxanthine 5831:-methyladenosine 5775: 5765: 5744: 5737: 5730: 5721: 5646: 5641:Ion transporters 5455: 5152: 5137: 5132:Channel blockers 5112: 5105: 5098: 5089: 4993: 4909: 4759: 4680:-Methyladenosine 4657:5-Methylcytidine 4625: 4527: 4520: 4513: 4504: 4489: 4488: 4477: 4476: 4078: 4071: 4064: 4055: 4026:Nitrous oxide (N 3997: 3966:Gasotransmitters 3963: 3943: 3887: 3880: 3847: 3782:Anandamide (AEA) 3750:Endocannabinoids 3747: 3714: 3601:Serotonin (5-HT) 3566: 3385:Glutamate system 3382: 3373: 3352: 3345: 3338: 3329: 3323: 3322: 3312: 3303:(3): 1145ā€“1149. 3288: 3282: 3281: 3271: 3262:(5): 1061ā€“1064. 3247: 3241: 3240: 3204: 3198: 3197: 3187: 3163: 3157: 3156: 3128: 3119: 3113: 3112: 3110: 3109: 3102:Sleep Foundation 3094: 3088: 3087: 3077: 3045: 3039: 3038: 3017: 3011: 3010: 3000: 2976: 2970: 2969: 2932: 2926: 2925: 2915: 2905: 2888:(6): 3555ā€“3560. 2873: 2867: 2866: 2856: 2824: 2818: 2817: 2797: 2791: 2790: 2780: 2748: 2742: 2741: 2731: 2721: 2689: 2683: 2682: 2672: 2632: 2626: 2625: 2615: 2583: 2577: 2576: 2566: 2556: 2524: 2518: 2517: 2496: 2490: 2489: 2471: 2465: 2464: 2462: 2461: 2446: 2440: 2439: 2417: 2408: 2407: 2397: 2365: 2359: 2358: 2348: 2316: 2310: 2309: 2299: 2289: 2265: 2259: 2258: 2248: 2238: 2214: 2208: 2207: 2179: 2173: 2172: 2162: 2130: 2124: 2123: 2113: 2081: 2075: 2074: 2056: 2050: 2049: 2013: 2007: 2006: 1986: 1980: 1979: 1968: 1962: 1961: 1951: 1941: 1917: 1911: 1910: 1900: 1890: 1866: 1860: 1859: 1857: 1855: 1845: 1837: 1831: 1830: 1801: 1795: 1794: 1776: 1770: 1769: 1767: 1766: 1743: 1734: 1733: 1713: 1707: 1706: 1688: 1664: 1658: 1657: 1629: 1623: 1622: 1604: 1594: 1585:(3): 1591ā€“1625. 1570: 1564: 1563: 1545: 1539: 1538: 1525:10.1007/3418_004 1512: 1395:sleep-wake cycle 1204:second messenger 1131:Adenosine is an 977:contraindication 665:organic compound 647: 646: 639: 581: 561: 546: 540: 534: 528: 511: 500: 489: 488: 474: 472: 457: 437: 417: 397: 377: 357: 337: 317: 307: 306: 292: 216: 144: 90: 49: 40: 33: 31: 8407: 8406: 8402: 8401: 8400: 8398: 8397: 8396: 8337: 8336: 8335: 8330: 8313: 8304: 8110: 8101: 8030: 8021: 7868: 7859: 7854: 7735:Efpegsomatropin 7711: 7702: 7684: 7654: 7649: 7635: 7472: 7426: 7324: 7305: 7293: 7280: 7270: 7266:Propentofylline 7216:Benzodiazepines 7202: 7192: 7139: 7120: 7104: 6723: 6674:Sodium ferulate 6642:Radix puerariae 6617:Phenolphthalein 6317: 6310: 6295: 6287: 6188:Propentofylline 6128:Isovaleric acid 5812: 5804: 5764: 5756: 5751:Purine receptor 5748: 5718: 5713: 5712: 5697:Clinical trials 5672: 5631: 5598: 5588: 5564: 5555: 5546:Benzodiazepines 5532: 5523: 5492:cardioselective 5461: 5447: 5432: 5407: 5399: 5324: 5312: 5262: 5209: 5143: 5126: 5116: 5086: 5077: 5034: 4978: 4945: 4896: 4853: 4805: 4754: 4742: 4738:Deoxyxanthosine 4694: 4647:5-Methyluridine 4614: 4576:Purine analogue 4537: 4531: 4501: 4496: 4464: 4448:Scoring systems 4443: 4356: 4298: 4247: 4158: 4087: 4082: 4052: 4043: 4038: 4029: 4015: 3991: 3981: 3957: 3914: 3860: 3836: 3727: 3699: 3683: 3605: 3561:Biogenic amines 3551: 3528: 3477: 3451: 3377: 3361: 3356: 3326: 3290: 3289: 3285: 3249: 3248: 3244: 3206: 3205: 3201: 3165: 3164: 3160: 3153: 3126: 3121: 3120: 3116: 3107: 3105: 3096: 3095: 3091: 3047: 3046: 3042: 3019: 3018: 3014: 2978: 2977: 2973: 2944:(12): 763ā€“767. 2934: 2933: 2929: 2875: 2874: 2870: 2826: 2825: 2821: 2799: 2798: 2794: 2750: 2749: 2745: 2691: 2690: 2686: 2634: 2633: 2629: 2585: 2584: 2580: 2526: 2525: 2521: 2498: 2497: 2493: 2486: 2473: 2472: 2468: 2459: 2457: 2448: 2447: 2443: 2436: 2419: 2418: 2411: 2367: 2366: 2362: 2318: 2317: 2313: 2267: 2266: 2262: 2216: 2215: 2211: 2181: 2180: 2176: 2151:10.1038/nrd2638 2132: 2131: 2127: 2083: 2082: 2078: 2071: 2058: 2057: 2053: 2015: 2014: 2010: 1988: 1987: 1983: 1970: 1969: 1965: 1919: 1918: 1914: 1868: 1867: 1863: 1853: 1851: 1843: 1839: 1838: 1834: 1803: 1802: 1798: 1791: 1778: 1777: 1773: 1764: 1762: 1745: 1744: 1737: 1715: 1714: 1710: 1666: 1665: 1661: 1631: 1630: 1626: 1572: 1571: 1567: 1560: 1547: 1546: 1542: 1535: 1514: 1513: 1509: 1505: 1483: 1471: 1459:therapeutic use 1444:slow-wave sleep 1440:basal forebrain 1425:endocannabinoid 1391: 1375: 1368: 1340: 1322: 1313: 1265: 1259: 1254: 1226:red blood cells 1200: 1171: 1156: 1129: 1117: 1113: 1109: 1105: 1101: 1097: 1093: 1089: 1085: 1082:activity. The A 1073: 1069: 1065: 1061: 1056: 1050: 1035: 1014: 1007: 1000: 993: 986: 962: 949: 919:Methylxanthines 895: 840: 821: 752: 747: 681:glycosidic bond 678: 642: 640: 637:(what is this?) 634: 629: 626: 621: 616: 615: 604: 601: 596: 595: 584: 559: 549: 543: 537: 531: 492: 468: 460: 440: 420: 400: 380: 360: 340: 320: 303: 295: 275: 272: 247: 246: 214: 193:Protein binding 183:Bioavailability 175:Pharmacokinetic 169: 148: 118: 111: 97: 26: 17: 12: 11: 5: 8405: 8403: 8395: 8394: 8389: 8384: 8379: 8374: 8369: 8364: 8359: 8354: 8349: 8339: 8338: 8332: 8331: 8329: 8328: 8320: 8318: 8306: 8305: 8303: 8302: 8297: 8292: 8283: 8278: 8269: 8268: 8263: 8251: 8246: 8241: 8236: 8231: 8226: 8221: 8209: 8204: 8199: 8194: 8189: 8184: 8179: 8174: 8169: 8164: 8159: 8154: 8149: 8144: 8139: 8134: 8132:Cortistatin-14 8129: 8117: 8115: 8103: 8102: 8100: 8099: 8090: 8089: 8084: 8079: 8074: 8069: 8064: 8059: 8054: 8049: 8037: 8035: 8032:(somatocrinin) 8023: 8022: 8020: 8019: 8014: 8009: 8004: 7995: 7994: 7989: 7984: 7979: 7974: 7969: 7964: 7959: 7954: 7949: 7944: 7939: 7934: 7929: 7924: 7919: 7914: 7909: 7904: 7899: 7894: 7892:Cortistatin-14 7889: 7884: 7875: 7873: 7870:(somatostatin) 7861: 7860: 7858: 7857: 7843: 7842: 7833: 7832: 7827: 7818: 7817: 7812: 7807: 7802: 7797: 7792: 7787: 7782: 7777: 7772: 7767: 7762: 7757: 7752: 7747: 7745:Growth hormone 7742: 7737: 7732: 7727: 7725:Albusomatropin 7718: 7716: 7713:(somatotropin) 7704: 7703: 7685: 7683: 7682: 7675: 7668: 7660: 7651: 7650: 7640: 7637: 7636: 7634: 7633: 7619: 7618: 7613: 7608: 7603: 7598: 7593: 7588: 7583: 7578: 7573: 7568: 7563: 7558: 7553: 7548: 7543: 7538: 7533: 7528: 7523: 7518: 7513: 7508: 7503: 7498: 7493: 7484: 7482: 7478: 7477: 7474: 7473: 7471: 7470: 7465: 7460: 7455: 7450: 7445: 7440: 7434: 7432: 7428: 7427: 7425: 7424: 7419: 7414: 7409: 7404: 7397: 7392: 7387: 7382: 7377: 7372: 7367: 7362: 7355: 7353:Cinnamaldehyde 7350: 7345: 7340: 7335: 7329: 7327: 7313: 7299: 7298: 7295: 7294: 7292: 7291: 7285: 7283: 7272: 7271: 7269: 7268: 7263: 7258: 7256:Pentoxifylline 7253: 7248: 7243: 7238: 7233: 7228: 7223: 7218: 7213: 7207: 7205: 7194: 7193: 7191: 7190: 7185: 7180: 7175: 7170: 7165: 7160: 7155: 7150: 7144: 7142: 7128: 7114: 7113: 7110: 7109: 7106: 7105: 7103: 7102: 7097: 7092: 7087: 7082: 7077: 7072: 7067: 7062: 7057: 7052: 7047: 7042: 7037: 7032: 7027: 7022: 7017: 7012: 7007: 7002: 6997: 6992: 6987: 6982: 6977: 6972: 6967: 6962: 6957: 6952: 6947: 6942: 6933: 6932: 6927: 6922: 6917: 6912: 6907: 6902: 6897: 6892: 6887: 6882: 6877: 6872: 6867: 6862: 6857: 6852: 6847: 6842: 6837: 6832: 6827: 6822: 6817: 6812: 6807: 6802: 6797: 6792: 6787: 6782: 6777: 6772: 6767: 6762: 6757: 6752: 6747: 6742: 6733: 6731: 6725: 6724: 6722: 6721: 6716: 6711: 6699: 6694: 6689: 6671: 6666: 6661: 6656: 6651: 6646: 6634: 6629: 6624: 6619: 6614: 6609: 6604: 6599: 6594: 6589: 6584: 6579: 6574: 6569: 6564: 6559: 6554: 6549: 6544: 6539: 6534: 6529: 6524: 6519: 6507: 6502: 6497: 6492: 6487: 6482: 6477: 6472: 6467: 6462: 6457: 6452: 6447: 6442: 6433: 6432: 6427: 6422: 6417: 6412: 6407: 6402: 6397: 6392: 6387: 6382: 6377: 6372: 6367: 6362: 6357: 6352: 6347: 6342: 6337: 6332: 6323: 6321: 6301: 6289: 6288: 6286: 6285: 6280: 6275: 6270: 6265: 6260: 6255: 6250: 6245: 6240: 6235: 6230: 6225: 6220: 6215: 6210: 6205: 6200: 6195: 6190: 6185: 6180: 6178:Pentoxifylline 6175: 6170: 6165: 6160: 6155: 6150: 6145: 6140: 6135: 6133:Istradefylline 6130: 6125: 6120: 6115: 6110: 6105: 6100: 6095: 6090: 6085: 6080: 6075: 6070: 6065: 6060: 6055: 6050: 6045: 6040: 6035: 6030: 6025: 6020: 6015: 6010: 6005: 6000: 5991: 5990: 5985: 5980: 5975: 5970: 5965: 5960: 5955: 5950: 5945: 5937: 5932: 5927: 5922: 5917: 5912: 5907: 5902: 5897: 5892: 5887: 5882: 5877: 5872: 5867: 5862: 5857: 5848: 5843: 5838: 5833: 5827:2-(1-Hexynyl)- 5820: 5818: 5806: 5805: 5803: 5802: 5797: 5795:8-Aminoadenine 5788: 5786: 5772: 5758: 5757: 5749: 5747: 5746: 5739: 5732: 5724: 5715: 5714: 5711: 5710: 5709: 5708: 5705: 5694: 5688: 5682: 5681: 5678: 5677: 5674: 5673: 5671: 5670: 5665: 5660: 5654: 5652: 5643: 5637: 5636: 5633: 5632: 5630: 5629: 5624: 5619: 5614: 5608: 5606: 5600: 5599: 5597: 5596: 5583: 5578: 5568: 5566: 5562: 5557: 5556: 5554: 5553: 5548: 5543: 5537: 5535: 5530: 5525: 5524: 5522: 5521: 5520: 5519: 5514: 5509: 5504: 5499: 5489: 5484: 5479: 5473: 5471: 5452: 5438: 5437: 5434: 5433: 5431: 5430: 5425: 5419: 5417: 5401: 5400: 5398: 5397: 5392: 5387: 5382: 5377: 5372: 5367: 5362: 5357: 5352: 5347: 5342: 5336: 5334: 5318: 5317: 5314: 5313: 5311: 5310: 5305: 5300: 5295: 5290: 5285: 5280: 5274: 5272: 5264: 5263: 5261: 5260: 5259: 5258: 5253: 5248: 5236: 5235: 5234: 5221: 5219: 5211: 5210: 5208: 5207: 5202: 5197: 5192: 5187: 5182: 5180:Hydroquinidine 5177: 5172: 5166: 5164: 5149: 5134: 5128: 5127: 5117: 5115: 5114: 5107: 5100: 5092: 5083: 5082: 5079: 5078: 5076: 5075: 5070: 5065: 5060: 5055: 5050: 5045: 5039: 5036: 5035: 5033: 5032: 5027: 5022: 5017: 5012: 5007: 5002: 4996: 4990: 4984: 4983: 4980: 4979: 4977: 4976: 4971: 4966: 4961: 4956: 4950: 4947: 4946: 4944: 4943: 4938: 4933: 4928: 4923: 4918: 4912: 4906: 4902: 4901: 4898: 4897: 4895: 4894: 4889: 4884: 4879: 4874: 4869: 4863: 4861: 4855: 4854: 4852: 4851: 4846: 4841: 4836: 4831: 4826: 4821: 4815: 4813: 4807: 4806: 4804: 4803: 4798: 4793: 4788: 4783: 4778: 4773: 4767: 4765: 4763:Ribonucleotide 4756: 4748: 4747: 4744: 4743: 4741: 4740: 4735: 4730: 4725: 4720: 4715: 4713:Deoxyguanosine 4710: 4708:Deoxyadenosine 4704: 4702: 4696: 4695: 4693: 4692: 4687: 4682: 4674: 4669: 4664: 4659: 4654: 4649: 4644: 4639: 4633: 4631: 4629:Ribonucleoside 4622: 4616: 4615: 4613: 4612: 4607: 4606: 4605: 4600: 4595: 4590: 4580: 4579: 4578: 4573: 4568: 4563: 4558: 4547: 4545: 4539: 4538: 4532: 4530: 4529: 4522: 4515: 4507: 4498: 4497: 4495: 4494: 4482: 4469: 4466: 4465: 4463: 4462: 4457: 4451: 4449: 4445: 4444: 4442: 4441: 4435: 4429: 4423: 4417: 4411: 4405: 4399: 4393: 4387: 4382: 4376: 4370: 4368: 4358: 4357: 4355: 4354: 4349: 4344: 4339: 4334: 4329: 4324: 4319: 4308: 4306: 4300: 4299: 4297: 4296: 4291: 4286: 4281: 4276: 4271: 4266: 4261: 4255: 4253: 4249: 4248: 4246: 4245: 4240: 4234: 4228: 4223: 4221:Laryngeal tube 4218: 4213: 4207: 4201: 4195: 4189: 4183:Defibrillation 4180: 4175: 4172:Bag valve mask 4168: 4166: 4160: 4159: 4157: 4156: 4151: 4146: 4141: 4136: 4131: 4126: 4121: 4116: 4111: 4106: 4101: 4095: 4093: 4089: 4088: 4083: 4081: 4080: 4073: 4066: 4058: 4049: 4048: 4045: 4044: 4042: 4041: 4036: 4032: 4027: 4023: 4018: 4013: 4009: 4003: 4001: 3993: 3992: 3990: 3989: 3984: 3979: 3975: 3969: 3967: 3959: 3958: 3956: 3955: 3949: 3947: 3940: 3936: 3935: 3931: 3924: 3923: 3920: 3919: 3916: 3915: 3913: 3912: 3907: 3902: 3896: 3894: 3884: 3877: 3870: 3869: 3866: 3865: 3862: 3861: 3859: 3858: 3850: 3844: 3838: 3837: 3835: 3834: 3829: 3824: 3819: 3814: 3809: 3804: 3799: 3794: 3789: 3784: 3779: 3774: 3769: 3764: 3759: 3753: 3751: 3744: 3737: 3736: 3733: 3732: 3729: 3728: 3726: 3725: 3717: 3711: 3705: 3704: 3701: 3700: 3698: 3697: 3691: 3689: 3685: 3684: 3682: 3681: 3673: 3665: 3660: 3655: 3653:Phenethylamine 3650: 3645: 3637: 3629: 3624: 3619: 3613: 3611: 3607: 3606: 3604: 3603: 3598: 3593: 3588: 3583: 3578: 3572: 3570: 3563: 3557: 3556: 3553: 3552: 3550: 3549: 3544: 3538: 3536: 3530: 3529: 3527: 3526: 3521: 3516: 3511: 3506: 3501: 3496: 3491: 3485: 3483: 3482:Glycine system 3479: 3478: 3476: 3475: 3470: 3465: 3459: 3457: 3453: 3452: 3450: 3449: 3444: 3439: 3434: 3429: 3427:Kynurenic acid 3424: 3419: 3414: 3409: 3404: 3399: 3394: 3388: 3386: 3379: 3370: 3363: 3362: 3357: 3355: 3354: 3347: 3340: 3332: 3325: 3324: 3283: 3242: 3199: 3178:(8): 943ā€“947. 3158: 3151: 3114: 3089: 3040: 3029:(3): 155ā€“159. 3012: 2991:(2): 195ā€“201. 2971: 2927: 2868: 2819: 2792: 2763:(4): 463ā€“474. 2743: 2684: 2627: 2578: 2519: 2508:(4): 245ā€“252. 2491: 2484: 2466: 2441: 2434: 2409: 2360: 2331:(6): 355ā€“367. 2311: 2260: 2209: 2174: 2145:(9): 759ā€“770. 2125: 2076: 2069: 2051: 2008: 1997:(2): 637ā€“642. 1981: 1978:on 2011-07-15. 1963: 1912: 1881:(1): 432ā€“439. 1861: 1848:regionsems.com 1832: 1813:(3): 614ā€“621. 1796: 1789: 1771: 1735: 1708: 1679:(2): 414ā€“424. 1659: 1624: 1565: 1558: 1540: 1533: 1506: 1504: 1501: 1500: 1499: 1494: 1489: 1482: 1479: 1470: 1467: 1450:, mediated by 1430:(AEA) induces 1423:(THC) and the 1390: 1387: 1374: 1371: 1366: 1339: 1336: 1320: 1319:agent at the A 1312: 1309: 1273:RNA polymerase 1258: 1255: 1253: 1250: 1240:vasodilatation 1199: 1196: 1192:coronary steal 1169: 1155: 1152: 1148:growth hormone 1128: 1125: 1118:and stimulate 1115: 1111: 1107: 1103: 1099: 1095: 1091: 1087: 1083: 1071: 1067: 1063: 1059: 1052:Main article: 1049: 1046: 1033: 1012: 1005: 998: 991: 985: 982: 981: 980: 961: 958: 947: 894: 891: 839: 836: 820: 817: 790:atrial flutter 751: 748: 746: 743: 693:deoxyadenosine 676: 671:attached to a 649: 648: 631: 630: 628: 627: 624: 622: 619: 611: 610: 609: 606: 605: 603: 602: 599: 591: 590: 589: 586: 585: 583: 582: 574: 572: 564: 563: 557: 551: 550: 547: 541: 535: 529: 524: 518: 517: 513: 512: 502: 494: 493: 491: 490: 477: 475: 462: 461: 459: 458: 450: 448: 442: 441: 439: 438: 430: 428: 422: 421: 419: 418: 410: 408: 402: 401: 399: 398: 390: 388: 382: 381: 379: 378: 370: 368: 362: 361: 359: 358: 350: 348: 342: 341: 339: 338: 330: 328: 322: 321: 319: 318: 310: 308: 297: 296: 294: 293: 285: 283: 277: 276: 274: 273: 267:)-2-(6-amino-9 250: 242: 241: 240: 237: 236: 232: 231: 228: 222: 221: 218: 209: 208: 205: 199: 198: 195: 189: 188: 185: 179: 178: 171: 170: 168: 167: 163: 161: 155: 154: 150: 149: 147: 146: 133: 131: 125: 124: 121: 119:administration 113: 112: 107: 106: 102: 100: 92: 91: 84: 74: 73: 70: 66: 65: 62: 56: 55: 51: 50: 42: 41: 15: 13: 10: 9: 6: 4: 3: 2: 8404: 8393: 8390: 8388: 8385: 8383: 8380: 8378: 8375: 8373: 8370: 8368: 8365: 8363: 8360: 8358: 8355: 8353: 8350: 8348: 8345: 8344: 8342: 8326: 8322: 8321: 8319: 8317: 8315:(somatomedin) 8307: 8301: 8298: 8296: 8293: 8291: 8290:-LysĀ³)-GHRP-6 8284: 8282: 8281:Cortistatin-8 8279: 8277: 8274: 8271: 8270: 8267: 8264: 8262: 8259: 8255: 8252: 8250: 8247: 8245: 8242: 8240: 8237: 8235: 8232: 8230: 8227: 8225: 8222: 8220: 8217: 8213: 8210: 8208: 8205: 8203: 8200: 8198: 8195: 8193: 8190: 8188: 8185: 8183: 8180: 8178: 8175: 8173: 8170: 8168: 8165: 8163: 8160: 8158: 8155: 8153: 8150: 8148: 8145: 8143: 8140: 8138: 8135: 8133: 8130: 8128: 8125: 8122: 8119: 8118: 8116: 8114: 8104: 8098: 8095: 8092: 8091: 8088: 8085: 8083: 8080: 8078: 8075: 8073: 8070: 8068: 8065: 8063: 8060: 8058: 8055: 8053: 8050: 8048: 8045: 8042: 8039: 8038: 8036: 8034: 8024: 8018: 8015: 8013: 8010: 8008: 8005: 8003: 8000: 7997: 7996: 7993: 7990: 7988: 7985: 7983: 7980: 7978: 7975: 7973: 7970: 7968: 7965: 7963: 7960: 7958: 7955: 7953: 7950: 7948: 7947:Pentetreotide 7945: 7943: 7940: 7938: 7935: 7933: 7930: 7928: 7925: 7923: 7920: 7918: 7915: 7913: 7910: 7908: 7905: 7903: 7900: 7898: 7895: 7893: 7890: 7888: 7885: 7883: 7880: 7877: 7876: 7874: 7872: 7862: 7853: 7848: 7845: 7844: 7841: 7838: 7835: 7834: 7831: 7828: 7826: 7823: 7820: 7819: 7816: 7813: 7811: 7808: 7806: 7803: 7801: 7798: 7796: 7793: 7791: 7788: 7786: 7783: 7781: 7778: 7776: 7773: 7771: 7768: 7766: 7763: 7761: 7758: 7756: 7753: 7751: 7748: 7746: 7743: 7741: 7738: 7736: 7733: 7731: 7728: 7726: 7723: 7720: 7719: 7717: 7715: 7705: 7701: 7698: 7695: 7681: 7676: 7674: 7669: 7667: 7662: 7661: 7658: 7648: 7647: 7644: 7638: 7631: 7627: 7624: 7621: 7620: 7617: 7614: 7612: 7609: 7607: 7604: 7602: 7599: 7597: 7594: 7592: 7589: 7587: 7584: 7582: 7579: 7577: 7574: 7572: 7569: 7567: 7564: 7562: 7559: 7557: 7554: 7552: 7549: 7547: 7544: 7542: 7539: 7537: 7534: 7532: 7529: 7527: 7524: 7522: 7519: 7517: 7514: 7512: 7509: 7507: 7504: 7502: 7499: 7497: 7494: 7492: 7489: 7486: 7485: 7483: 7479: 7469: 7466: 7464: 7461: 7459: 7456: 7454: 7451: 7449: 7446: 7444: 7441: 7439: 7436: 7435: 7433: 7429: 7423: 7420: 7418: 7415: 7413: 7410: 7408: 7405: 7403: 7402: 7398: 7396: 7393: 7391: 7388: 7386: 7383: 7381: 7378: 7376: 7373: 7371: 7368: 7366: 7363: 7361: 7360: 7356: 7354: 7351: 7349: 7346: 7344: 7343:Benzbromarone 7341: 7339: 7336: 7334: 7331: 7330: 7328: 7323: 7317: 7314: 7310: 7304: 7300: 7290: 7287: 7286: 7284: 7279: 7273: 7267: 7264: 7262: 7259: 7257: 7254: 7252: 7249: 7247: 7244: 7242: 7239: 7237: 7234: 7232: 7229: 7227: 7224: 7222: 7219: 7217: 7214: 7212: 7209: 7208: 7206: 7201: 7195: 7189: 7186: 7184: 7181: 7179: 7176: 7174: 7171: 7169: 7166: 7164: 7161: 7159: 7156: 7154: 7151: 7149: 7146: 7145: 7143: 7138: 7132: 7129: 7125: 7119: 7115: 7101: 7098: 7096: 7093: 7091: 7088: 7086: 7083: 7081: 7078: 7076: 7073: 7071: 7068: 7066: 7063: 7061: 7058: 7056: 7053: 7051: 7048: 7046: 7043: 7041: 7038: 7036: 7033: 7031: 7028: 7026: 7023: 7021: 7018: 7016: 7013: 7011: 7008: 7006: 7003: 7001: 6998: 6996: 6993: 6991: 6988: 6986: 6983: 6981: 6978: 6976: 6975:AR-C 118925XX 6973: 6971: 6968: 6966: 6963: 6961: 6958: 6956: 6953: 6951: 6948: 6946: 6943: 6941: 6938: 6935: 6934: 6931: 6928: 6926: 6923: 6921: 6918: 6916: 6913: 6911: 6908: 6906: 6905:UDP-galactose 6903: 6901: 6898: 6896: 6893: 6891: 6888: 6886: 6883: 6881: 6878: 6876: 6873: 6871: 6868: 6866: 6863: 6861: 6858: 6856: 6853: 6851: 6848: 6846: 6843: 6841: 6838: 6836: 6833: 6831: 6828: 6826: 6823: 6821: 6818: 6816: 6813: 6811: 6808: 6806: 6803: 6801: 6798: 6796: 6793: 6791: 6788: 6786: 6783: 6781: 6778: 6776: 6773: 6771: 6768: 6766: 6763: 6761: 6758: 6756: 6753: 6751: 6748: 6746: 6743: 6741: 6738: 6735: 6734: 6732: 6730: 6726: 6720: 6717: 6715: 6712: 6709: 6708: 6703: 6700: 6698: 6695: 6693: 6690: 6687: 6686: 6681: 6680: 6675: 6672: 6670: 6667: 6665: 6662: 6660: 6657: 6655: 6652: 6650: 6647: 6644: 6643: 6638: 6635: 6633: 6630: 6628: 6625: 6623: 6620: 6618: 6615: 6613: 6610: 6608: 6605: 6603: 6600: 6598: 6595: 6593: 6590: 6588: 6585: 6583: 6580: 6578: 6575: 6573: 6570: 6568: 6565: 6563: 6560: 6558: 6555: 6553: 6550: 6548: 6545: 6543: 6540: 6538: 6535: 6533: 6530: 6528: 6525: 6523: 6520: 6517: 6516: 6511: 6508: 6506: 6503: 6501: 6500:Chelerythrine 6498: 6496: 6495:Calmidazolium 6493: 6491: 6488: 6486: 6483: 6481: 6478: 6476: 6473: 6471: 6468: 6466: 6463: 6461: 6458: 6456: 6453: 6451: 6448: 6446: 6443: 6441: 6438: 6435: 6434: 6431: 6428: 6426: 6423: 6421: 6418: 6416: 6413: 6411: 6408: 6406: 6403: 6401: 6398: 6396: 6393: 6391: 6388: 6386: 6383: 6381: 6380:Cibacron blue 6378: 6376: 6373: 6371: 6368: 6366: 6363: 6361: 6358: 6356: 6353: 6351: 6348: 6346: 6343: 6341: 6338: 6336: 6333: 6331: 6328: 6325: 6324: 6322: 6316: 6309: 6305: 6302: 6299: 6294: 6290: 6284: 6281: 6279: 6276: 6274: 6271: 6269: 6266: 6264: 6261: 6259: 6258:Theodrenaline 6256: 6254: 6251: 6249: 6246: 6244: 6241: 6239: 6236: 6234: 6231: 6229: 6226: 6224: 6221: 6219: 6216: 6214: 6211: 6209: 6206: 6204: 6201: 6199: 6196: 6194: 6193:Proxyphylline 6191: 6189: 6186: 6184: 6181: 6179: 6176: 6174: 6171: 6169: 6166: 6164: 6161: 6159: 6156: 6154: 6151: 6149: 6146: 6144: 6141: 6139: 6136: 6134: 6131: 6129: 6126: 6124: 6121: 6119: 6116: 6114: 6111: 6109: 6106: 6104: 6101: 6099: 6096: 6094: 6091: 6089: 6086: 6084: 6081: 6079: 6076: 6074: 6071: 6069: 6066: 6064: 6061: 6059: 6056: 6054: 6051: 6049: 6046: 6044: 6041: 6039: 6036: 6034: 6031: 6029: 6026: 6024: 6023:Aminophylline 6021: 6019: 6016: 6014: 6011: 6009: 6006: 6004: 6001: 5999: 5996: 5993: 5992: 5989: 5986: 5984: 5981: 5979: 5976: 5974: 5971: 5969: 5966: 5964: 5961: 5959: 5956: 5954: 5951: 5949: 5946: 5944: 5942: 5938: 5936: 5933: 5931: 5928: 5926: 5923: 5921: 5918: 5916: 5913: 5911: 5908: 5906: 5903: 5901: 5898: 5896: 5893: 5891: 5888: 5886: 5883: 5881: 5878: 5876: 5873: 5871: 5868: 5866: 5863: 5861: 5858: 5856: 5854: 5849: 5847: 5844: 5842: 5839: 5837: 5834: 5832: 5830: 5825: 5822: 5821: 5819: 5816: 5811: 5807: 5801: 5798: 5796: 5793: 5790: 5789: 5787: 5784: 5780: 5776: 5773: 5769: 5763: 5759: 5755: 5752: 5745: 5740: 5738: 5733: 5731: 5726: 5725: 5722: 5706: 5704: 5701: 5700: 5698: 5695: 5692: 5689: 5687: 5684: 5683: 5679: 5669: 5666: 5664: 5661: 5659: 5656: 5655: 5653: 5651: 5647: 5644: 5642: 5638: 5628: 5625: 5623: 5620: 5618: 5615: 5613: 5610: 5609: 5607: 5605: 5601: 5595: 5591: 5587: 5584: 5582: 5579: 5577: 5573: 5570: 5569: 5567: 5565: 5558: 5552: 5549: 5547: 5544: 5542: 5539: 5538: 5536: 5534: 5526: 5518: 5515: 5513: 5510: 5508: 5505: 5503: 5500: 5498: 5495: 5494: 5493: 5490: 5488: 5485: 5483: 5480: 5478: 5475: 5474: 5472: 5469: 5465: 5460: 5456: 5453: 5451: 5446: 5443: 5439: 5429: 5426: 5424: 5421: 5420: 5418: 5415: 5411: 5406: 5402: 5396: 5393: 5391: 5388: 5386: 5383: 5381: 5378: 5376: 5373: 5371: 5368: 5366: 5363: 5361: 5358: 5356: 5353: 5351: 5348: 5346: 5343: 5341: 5338: 5337: 5335: 5332: 5328: 5323: 5319: 5309: 5306: 5304: 5301: 5299: 5296: 5294: 5291: 5289: 5286: 5284: 5281: 5279: 5276: 5275: 5273: 5270: 5265: 5257: 5254: 5252: 5249: 5247: 5244: 5243: 5242: 5241: 5237: 5233: 5230: 5229: 5228: 5227: 5223: 5222: 5220: 5217: 5212: 5206: 5203: 5201: 5198: 5196: 5193: 5191: 5188: 5186: 5183: 5181: 5178: 5176: 5173: 5171: 5168: 5167: 5165: 5162: 5158: 5153: 5150: 5147: 5142: 5138: 5135: 5133: 5129: 5124: 5120: 5113: 5108: 5106: 5101: 5099: 5094: 5093: 5090: 5074: 5071: 5069: 5066: 5064: 5061: 5059: 5056: 5054: 5051: 5049: 5046: 5044: 5041: 5040: 5037: 5031: 5028: 5026: 5023: 5021: 5018: 5016: 5013: 5011: 5008: 5006: 5003: 5001: 4998: 4997: 4994: 4991: 4989: 4985: 4975: 4972: 4970: 4967: 4965: 4962: 4960: 4957: 4955: 4952: 4951: 4948: 4942: 4939: 4937: 4934: 4932: 4929: 4927: 4924: 4922: 4919: 4917: 4914: 4913: 4910: 4907: 4903: 4893: 4890: 4888: 4885: 4883: 4880: 4878: 4875: 4873: 4870: 4868: 4865: 4864: 4862: 4860: 4856: 4850: 4847: 4845: 4842: 4840: 4837: 4835: 4832: 4830: 4827: 4825: 4822: 4820: 4817: 4816: 4814: 4812: 4808: 4802: 4799: 4797: 4794: 4792: 4789: 4787: 4784: 4782: 4779: 4777: 4774: 4772: 4769: 4768: 4766: 4764: 4760: 4757: 4753: 4749: 4739: 4736: 4734: 4731: 4729: 4728:Deoxycytidine 4726: 4724: 4721: 4719: 4716: 4714: 4711: 4709: 4706: 4705: 4703: 4701: 4697: 4691: 4688: 4686: 4683: 4681: 4679: 4675: 4673: 4670: 4668: 4667:Pseudouridine 4665: 4663: 4660: 4658: 4655: 4653: 4650: 4648: 4645: 4643: 4640: 4638: 4635: 4634: 4632: 4630: 4626: 4623: 4621: 4617: 4611: 4608: 4604: 4601: 4599: 4596: 4594: 4591: 4589: 4586: 4585: 4584: 4581: 4577: 4574: 4572: 4569: 4567: 4564: 4562: 4559: 4557: 4554: 4553: 4552: 4549: 4548: 4546: 4544: 4540: 4535: 4528: 4523: 4521: 4516: 4514: 4509: 4508: 4505: 4493: 4492: 4483: 4481: 4480: 4471: 4470: 4467: 4461: 4458: 4456: 4453: 4452: 4450: 4446: 4439: 4436: 4433: 4430: 4427: 4424: 4421: 4418: 4415: 4412: 4409: 4406: 4403: 4400: 4397: 4394: 4391: 4388: 4386: 4383: 4380: 4377: 4375: 4372: 4371: 4369: 4367: 4363: 4359: 4353: 4350: 4348: 4345: 4343: 4340: 4338: 4335: 4333: 4330: 4328: 4325: 4323: 4320: 4317: 4313: 4310: 4309: 4307: 4305: 4304:Organisations 4301: 4295: 4292: 4290: 4287: 4285: 4282: 4280: 4277: 4275: 4272: 4270: 4267: 4265: 4262: 4260: 4257: 4256: 4254: 4250: 4244: 4241: 4238: 4235: 4232: 4229: 4227: 4224: 4222: 4219: 4217: 4214: 4211: 4208: 4205: 4202: 4199: 4196: 4193: 4190: 4188: 4184: 4181: 4179: 4176: 4173: 4170: 4169: 4167: 4165: 4161: 4155: 4152: 4150: 4149:Trauma center 4147: 4145: 4142: 4140: 4137: 4135: 4132: 4130: 4127: 4125: 4122: 4120: 4117: 4115: 4112: 4110: 4107: 4105: 4102: 4100: 4097: 4096: 4094: 4090: 4086: 4079: 4074: 4072: 4067: 4065: 4060: 4059: 4056: 4040: 4033: 4031: 4024: 4022: 4019: 4017: 4010: 4008: 4005: 4004: 4002: 3998: 3988: 3985: 3983: 3976: 3974: 3971: 3970: 3968: 3964: 3954: 3953:Acetylcholine 3951: 3950: 3948: 3944: 3941: 3939:Miscellaneous 3937: 3932: 3929: 3925: 3911: 3908: 3906: 3903: 3901: 3898: 3897: 3895: 3892: 3888: 3885: 3881: 3878: 3875: 3871: 3856: 3852: 3851: 3848: 3845: 3843: 3842:Neurosteroids 3839: 3833: 3830: 3828: 3825: 3823: 3820: 3818: 3815: 3813: 3810: 3808: 3805: 3803: 3800: 3798: 3795: 3793: 3790: 3788: 3785: 3783: 3780: 3778: 3775: 3773: 3770: 3768: 3765: 3763: 3760: 3758: 3755: 3754: 3752: 3748: 3745: 3742: 3738: 3723: 3719: 3718: 3715: 3712: 3710: 3709:Neuropeptides 3706: 3696: 3693: 3692: 3690: 3686: 3680: 3678: 3674: 3672: 3670: 3666: 3664: 3661: 3659: 3656: 3654: 3651: 3649: 3646: 3644: 3642: 3638: 3636: 3634: 3630: 3628: 3625: 3623: 3620: 3618: 3615: 3614: 3612: 3608: 3602: 3599: 3597: 3594: 3592: 3589: 3587: 3584: 3582: 3579: 3577: 3574: 3573: 3571: 3567: 3564: 3562: 3558: 3548: 3545: 3543: 3540: 3539: 3537: 3535: 3531: 3525: 3522: 3520: 3517: 3515: 3512: 3510: 3507: 3505: 3502: 3500: 3497: 3495: 3492: 3490: 3487: 3486: 3484: 3480: 3474: 3471: 3469: 3466: 3464: 3461: 3460: 3458: 3454: 3448: 3445: 3443: 3440: 3438: 3435: 3433: 3430: 3428: 3425: 3423: 3420: 3418: 3415: 3413: 3410: 3408: 3405: 3403: 3400: 3398: 3395: 3393: 3390: 3389: 3387: 3383: 3380: 3374: 3371: 3368: 3364: 3360: 3353: 3348: 3346: 3341: 3339: 3334: 3333: 3330: 3320: 3316: 3311: 3306: 3302: 3298: 3294: 3287: 3284: 3279: 3275: 3270: 3265: 3261: 3257: 3253: 3246: 3243: 3238: 3234: 3230: 3226: 3222: 3218: 3214: 3210: 3203: 3200: 3195: 3191: 3186: 3181: 3177: 3173: 3169: 3162: 3159: 3154: 3152:9781416066453 3148: 3144: 3140: 3136: 3132: 3125: 3118: 3115: 3103: 3099: 3093: 3090: 3085: 3081: 3076: 3071: 3067: 3063: 3060:(4): e13597. 3059: 3055: 3051: 3044: 3041: 3036: 3032: 3028: 3024: 3016: 3013: 3008: 3004: 2999: 2994: 2990: 2986: 2982: 2975: 2972: 2967: 2963: 2959: 2955: 2951: 2947: 2943: 2939: 2931: 2928: 2923: 2919: 2914: 2909: 2904: 2899: 2895: 2891: 2887: 2883: 2879: 2872: 2869: 2864: 2860: 2855: 2850: 2846: 2842: 2838: 2834: 2830: 2823: 2820: 2815: 2811: 2807: 2803: 2796: 2793: 2788: 2784: 2779: 2774: 2770: 2766: 2762: 2758: 2754: 2747: 2744: 2739: 2735: 2730: 2725: 2720: 2715: 2711: 2707: 2703: 2699: 2695: 2688: 2685: 2680: 2676: 2671: 2666: 2662: 2658: 2654: 2650: 2646: 2642: 2638: 2631: 2628: 2623: 2619: 2614: 2609: 2605: 2601: 2597: 2593: 2589: 2582: 2579: 2574: 2570: 2565: 2560: 2555: 2550: 2546: 2542: 2538: 2534: 2530: 2523: 2520: 2515: 2511: 2507: 2503: 2495: 2492: 2487: 2481: 2477: 2470: 2467: 2455: 2451: 2445: 2442: 2437: 2431: 2427: 2423: 2416: 2414: 2410: 2405: 2401: 2396: 2391: 2387: 2383: 2379: 2375: 2371: 2364: 2361: 2356: 2352: 2347: 2342: 2338: 2334: 2330: 2326: 2322: 2315: 2312: 2307: 2303: 2298: 2293: 2288: 2283: 2279: 2275: 2271: 2264: 2261: 2256: 2252: 2247: 2242: 2237: 2232: 2228: 2224: 2220: 2213: 2210: 2205: 2201: 2197: 2193: 2189: 2185: 2178: 2175: 2170: 2166: 2161: 2156: 2152: 2148: 2144: 2140: 2136: 2129: 2126: 2121: 2117: 2112: 2107: 2103: 2099: 2095: 2091: 2087: 2080: 2077: 2072: 2066: 2062: 2055: 2052: 2047: 2043: 2039: 2035: 2031: 2027: 2023: 2019: 2012: 2009: 2004: 2000: 1996: 1992: 1985: 1982: 1977: 1973: 1967: 1964: 1959: 1955: 1950: 1945: 1940: 1935: 1931: 1927: 1923: 1916: 1913: 1908: 1904: 1899: 1894: 1889: 1884: 1880: 1876: 1872: 1865: 1862: 1849: 1842: 1836: 1833: 1828: 1824: 1820: 1816: 1812: 1808: 1800: 1797: 1792: 1790:0-7923-6170-9 1786: 1782: 1775: 1772: 1761: 1757: 1753: 1749: 1742: 1740: 1736: 1731: 1727: 1723: 1719: 1712: 1709: 1704: 1700: 1696: 1692: 1687: 1682: 1678: 1674: 1670: 1663: 1660: 1655: 1651: 1647: 1643: 1639: 1635: 1628: 1625: 1620: 1616: 1612: 1608: 1603: 1602:11392/2391482 1598: 1593: 1588: 1584: 1580: 1576: 1569: 1566: 1561: 1559:0-7167-4339-6 1555: 1551: 1544: 1541: 1536: 1534:3-540-33047-X 1530: 1526: 1522: 1518: 1511: 1508: 1502: 1498: 1495: 1493: 1490: 1488: 1485: 1484: 1480: 1478: 1476: 1468: 1466: 1464: 1460: 1456: 1453: 1449: 1445: 1441: 1437: 1433: 1429: 1426: 1422: 1419: 1414: 1412: 1408: 1404: 1400: 1396: 1388: 1386: 1384: 1380: 1372: 1370: 1364: 1360: 1356: 1353: 1349: 1345: 1337: 1335: 1333: 1329: 1326: 1318: 1310: 1308: 1306: 1302: 1298: 1294: 1290: 1286: 1282: 1278: 1274: 1270: 1264: 1256: 1251: 1249: 1247: 1243: 1241: 1237: 1233: 1229: 1227: 1223: 1218: 1216: 1212: 1209: 1205: 1197: 1195: 1193: 1187: 1185: 1181: 1177: 1173: 1165: 1161: 1153: 1151: 1149: 1145: 1141: 1137: 1134: 1126: 1124: 1121: 1120:phospholipase 1081: 1077: 1055: 1047: 1045: 1043: 1039: 1031: 1027: 1022: 1017: 1015: 1008: 1001: 994: 983: 978: 974: 971: 970: 969: 967: 959: 957: 955: 954:acetylcholine 951: 943: 939: 936: 932: 928: 924: 920: 913: 909: 905: 901: 899: 892: 890: 888: 884: 880: 876: 872: 868: 864: 860: 855: 853: 849: 845: 837: 835: 833: 830: 826: 818: 816: 814: 810: 806: 801: 799: 795: 791: 787: 783: 778: 776: 772: 768: 764: 759: 757: 749: 744: 742: 740: 736: 732: 728: 724: 721:(abbreviated 720: 716: 714: 710: 706: 702: 698: 694: 690: 686: 682: 674: 670: 666: 662: 659: 655: 645: 638: 632: 623: 618: 614: 607: 598: 594: 587: 580: 576: 575: 573: 570: 565: 558: 556: 552: 525: 523: 519: 514: 510: 506: 503: 501: 499:ECHA InfoCard 495: 487: 483: 482:DTXSID1022558 479: 478: 476: 467: 463: 456: 452: 451: 449: 447: 443: 436: 432: 431: 429: 427: 423: 416: 412: 411: 409: 407: 403: 396: 392: 391: 389: 387: 383: 376: 372: 371: 369: 367: 363: 356: 352: 351: 349: 347: 343: 336: 332: 331: 329: 327: 323: 316: 312: 311: 309: 302: 298: 291: 287: 286: 284: 282: 278: 270: 266: 262: 258: 254: 249: 245: 238: 233: 229: 227: 223: 219: 217: 210: 206: 204: 200: 196: 194: 190: 186: 184: 180: 176: 172: 165: 164: 162: 160: 156: 151: 143: 138: 135: 134: 132: 130: 126: 122: 120: 114: 110: 104: 103: 101: 99: 93: 89: 85: 83: 79: 75: 71: 67: 63: 61: 57: 54:Clinical data 52: 48: 43: 39: 34: 24: 19: 8387:Vasodilators 8273:Antagonists: 8272: 8257: 8229:Capromorelin 8218: 8216:Non-peptide: 8215: 8127:Alexamorelin 8123: 8120: 8094:Antagonists: 8093: 8043: 8040: 7999:Antagonists: 7998: 7992:Veldoreotide 7878: 7846: 7836: 7822:Antagonists: 7821: 7780:Somatotropin 7721: 7642: 7641: 7626:Chrysophanol 7622: 7566:Hypoxanthine 7495: 7487: 7467: 7463:Pralatrexate 7448:Methotrexate 7443:Azathioprine 7422:Topiroxostat 7399: 7370:Myo-inositol 7357: 7348:Caffeic acid 7261:Progesterone 7231:Dipyridamole 7211:Barbiturates 7188:Progesterone 7152: 6970:AR-C 69931MX 6965:AR-C 67085MX 6937:Antagonists: 6936: 6790:AR-C 67085MX 6769: 6736: 6705: 6683: 6677: 6640: 6607:Oxidized-ATP 6552:JNJ-47965567 6513: 6437:Antagonists: 6436: 6410:L-Ī²,Ī³-Me-ATP 6390:D-Ī²,Ī³-Me-ATP 6339: 6326: 6263:Theophylline 6173:Paraxanthine 6118:Fenethylline 6108:Enprofylline 6073:Ciforadenant 5995:Antagonists: 5994: 5958:Piclidenoson 5940: 5859: 5852: 5836:2-Cl-IB-MECA 5828: 5823: 5814: 5791: 5650:Na/ K-ATPase 5581:Disopyramide 5551:Barbiturates 5540: 5491: 5238: 5224: 5195:Procainamide 5175:Disopyramide 4733:Deoxyinosine 4723:Deoxyuridine 4677: 4636: 4566:Hypoxanthine 4536:constituents 4534:Nucleic acid 4484: 4472: 4366:Life support 4258: 4144:Major trauma 4007:Acetaldehyde 3890: 3676: 3668: 3640: 3632: 3610:Trace amines 3300: 3296: 3286: 3259: 3256:Hypertension 3255: 3245: 3212: 3208: 3202: 3175: 3171: 3161: 3134: 3130: 3117: 3106:. Retrieved 3104:. 2022-06-07 3101: 3092: 3057: 3053: 3043: 3026: 3022: 3015: 2988: 2984: 2974: 2941: 2937: 2930: 2885: 2881: 2871: 2836: 2832: 2822: 2805: 2801: 2795: 2760: 2756: 2746: 2704:(5): e2107. 2701: 2697: 2687: 2644: 2640: 2630: 2595: 2591: 2581: 2536: 2532: 2522: 2505: 2501: 2494: 2475: 2469: 2458:. Retrieved 2453: 2444: 2425: 2377: 2373: 2363: 2328: 2324: 2314: 2277: 2273: 2263: 2229:(12): 3837. 2226: 2222: 2212: 2190:(1): 33ā€“39. 2187: 2183: 2177: 2142: 2138: 2128: 2093: 2089: 2079: 2060: 2054: 2021: 2017: 2011: 1994: 1990: 1984: 1976:the original 1972:"Vitamin B4" 1966: 1929: 1925: 1915: 1878: 1874: 1864: 1852:. Retrieved 1850:. April 2016 1847: 1835: 1810: 1806: 1799: 1783:. Springer. 1780: 1774: 1763:. Retrieved 1751: 1721: 1717: 1711: 1676: 1672: 1662: 1637: 1633: 1627: 1582: 1578: 1568: 1549: 1543: 1516: 1510: 1475:vasodilation 1472: 1469:Vasodilation 1463:cannabinoids 1452:CB1 receptor 1415: 1392: 1376: 1363:Trk receptor 1341: 1332:Methotrexate 1330: 1314: 1283:and rise in 1277:dengue virus 1266: 1244: 1232:Dipyridamole 1230: 1219: 1207: 1201: 1188: 1157: 1130: 1057: 1038:inflammatory 1018: 987: 963: 940: 927:theophylline 917: 898:Dipyridamole 896: 859:dipyridamole 856: 841: 827:(TI 201) or 822: 802: 779: 760: 753: 745:Medical uses 726: 722: 718: 717: 660: 653: 652: 641:   635:   268: 264: 260: 256: 252: 213:Elimination 159:Legal status 153:Legal status 108: 18: 8372:Nucleosides 8249:Macimorelin 8207:Tabimorelin 8202:Relamorelin 8182:Lenomorelin 8087:Tesamorelin 8082:Somatorelin 8017:Satoreotide 7942:Pasireotide 7927:NNC 26-9100 7907:Ilatreotide 7902:Edotreotide 7840:Atesidorsen 7830:Pegvisomant 7805:Somavaratan 7795:Sometribove 7770:Somapacitan 7765:Somagrebove 7488:Precursors: 7468:Many others 7438:Aminopterin 7395:Phytic acid 7338:Amflutizole 7333:Allopurinol 7289:Decynium-22 7246:Hexobendine 7118:Transporter 7095:Ticlopidine 7000:Clopidogrel 6910:UDP-glucose 6649:Purotoxin 1 6480:AZ-11645373 6475:AZ-10606120 6273:Tracazolate 6253:Theobromine 6238:SCH-442,416 6233:Rolofylline 6183:Preladenant 6053:Cartazolate 6033:Bamifylline 5983:Tecadenoson 5978:Sonedenoson 5973:Selodenoson 5968:SDZ WAG 994 5963:Regadenoson 5948:Namodenoson 5900:Capadenoson 5895:Binodenoson 5890:BAY 60ā€“6583 5693:from market 5604:Ī± receptors 5487:Propranolol 5450:antagonists 5395:Vernakalant 5365:Dronedarone 5308:Propafenone 5293:Indecainide 4243:Pocket mask 4119:Golden hour 4012:Ammonia (NH 3883:Nucleosides 3643:-Octopamine 3635:-Octopamine 3547:T-HCA (GHC) 3504:Hypotaurine 3456:GABA system 3407:Glutathione 3297:Circulation 1448:sleep cycle 1446:during the 1180:endothelium 1160:heart block 946:adenosine A 931:theobromine 769:(AVRT) and 739:radical SAM 735:vitamin B12 562: gĀ·mol 505:100.000.354 435:CHEBI:16335 235:Identifiers 123:Intravenous 69:Other names 60:Trade names 8341:Categories 8224:Anamorelin 8212:Ulimorelin 8187:Livoletide 8177:Ipamorelin 8077:Sermorelin 8072:Rismorelin 8012:CYN-154806 7987:Vapreotide 7937:Octreotide 7932:Octreotate 7922:Lanreotide 7897:Depreotide 7815:Somidobove 7810:Somavubove 7775:Somatosalm 7700:modulators 7458:Pemetrexed 7417:Tisopurine 7390:Oxipurinol 7385:Niraxostat 7375:Kaempferol 7365:Febuxostat 7309:inhibitors 7221:Cilostazol 7183:Phloridzin 7090:Ticagrelor 6960:AR-C 66096 6820:Diquafosol 6765:Ī±,Ī²-Me-ATP 6750:2-Thio-UTP 6659:Ro 0437626 6612:Phenol Red 6527:Gefapixant 6522:Evans blue 6405:Ivermectin 6335:Ī±,Ī²-Me-ATP 6298:nucleotide 6283:ZM-241,385 6268:Tozadenant 6143:MRE3008F20 6103:Dyphylline 6088:Dimethazan 6018:Acefylline 5988:UK-432,097 5920:Evodenoson 5915:CP-532,903 5875:Apadenoson 5754:modulators 5612:Amiodarone 5517:Metoprolol 5497:Acebutolol 5468:Ī² blockers 5380:Nifekalant 5360:Dofetilide 5355:Celivarone 5340:Amiodarone 5303:Moracizine 5298:Lorcainide 5288:Flecainide 5283:Ethacizine 5267:class Ic ( 5251:Mexiletine 5214:class Ib ( 5190:Prajmaline 5155:class Ia ( 4752:Nucleotide 4690:Wybutosine 4685:Xanthosine 4620:Nucleoside 4583:Pyrimidine 4543:Nucleobase 4455:NACA score 4264:Amiodarone 4178:Chest tube 4000:Candidates 3874:Nucleobase 3663:Tryptamine 3658:Synephrine 3569:Monoamines 3534:GHB system 3367:Amino acid 3108:2023-04-12 2460:2021-03-22 1949:10451/6361 1765:2022-01-28 1752:StatPearls 1503:References 1455:activation 1428:anandamide 1399:sleepiness 1369:receptor. 1289:flavivirus 1261:See also: 1198:Metabolism 1133:endogenous 912:antagonist 889:patients. 809:cardiovert 794:ventricles 685:nucleoside 567:3D model ( 555:Molar mass 395:K72T3FS567 366:ChemSpider 326:IUPHAR/BPS 281:CAS Number 244:IUPAC name 203:Metabolism 8266:LY-444711 8261:LY-426410 8258:Unsorted: 8254:SM-130686 8244:L-692,585 8234:CP-464709 8219:Adenosine 8192:LY-444711 8121:Agonists: 8112:(ghrelin) 8057:Dumorelin 8047:ALRN-5281 8041:Agonists: 8002:BIM-23056 7957:Seglitide 7917:L-817,818 7912:L-803,087 7882:BIM-23052 7879:Agonists: 7825:G120K-hGH 7722:Agonists: 7697:signaling 7643:See also: 7546:Guanosine 7496:Adenosine 7412:Quercetin 7380:Myricetin 7236:Estradiol 7163:Estradiol 7153:Adenosine 7065:Prasugrel 7005:Elinogrel 6995:Cangrelor 6940:2-Me-SAMP 6880:PAPET-ATP 6840:INS-37217 6815:Denufosol 6770:Adenosine 6760:5-OMe-UDP 6745:2-Me-SATP 6740:2-Me-SADP 6737:Agonists: 6632:PSB-12062 6567:Magnesium 6532:GW-791343 6420:PAPET-ATP 6340:Adenosine 6330:2-Me-SATP 6327:Agonists: 6248:Theacrine 6243:SCH-58261 6228:Reversine 6113:Etazolate 6063:CGS-15943 6038:Cafedrine 5910:CGS-21680 5860:Adenosine 5841:2'-MeCCPA 5824:Agonists: 5815:adenosine 5792:Agonists: 5703:Phase III 5691:Withdrawn 5658:Digitoxin 5627:Verapamil 5622:Quinidine 5617:Bretylium 5586:Quinidine 5541:Adenosine 5512:Landiolol 5428:Verapamil 5423:Diltiazem 5390:Tedisamil 5375:Ibutilide 5350:Bunaftine 5345:Bretylium 5322:class III 5278:Encainide 5256:Tocainide 5246:Aprindine 5232:Lidocaine 5205:Sparteine 5200:Quinidine 5185:Lorajmine 4718:Thymidine 4642:Guanosine 4637:Adenosine 4374:First aid 4259:Adenosine 4226:Combitube 4200:(ECG/EKG) 4164:Equipment 3891:Adenosine 3695:Histamine 3679:-Tyramine 3671:-Tyramine 3514:Sarcosine 3494:Ī²-Alanine 3489:Ī±-Alanine 2280:(1): 52. 2046:235094871 1379:minoxidil 1359:glutamate 1285:cytokines 885:, and in 741:enzymes. 675:via a Ī²-N 654:Adenosine 455:ChEMBL477 226:Excretion 215:half-life 117:Routes of 96:Pregnancy 88:Monograph 82:Drugs.com 30:Adenosine 8327:instead. 8276:A-778193 8137:EP-51216 8124:Peptide: 8097:MZ-5-156 8052:CJC-1295 8044:Peptide: 7790:Somatrem 7521:Cytidine 7516:Cytosine 7407:Propolis 7173:KGO-2173 7168:KGO-2142 7158:dMeThPmR 7124:blockers 7080:Regrelor 7070:PSB-0739 7040:MRS-2578 7035:MRS-2500 7030:MRS-2395 7025:MRS-2279 7020:MRS-2211 7015:MRS-2179 6890:PSB-1114 6885:PSB-0474 6870:MRS-4062 6865:MRS-2957 6860:MRS-2768 6855:MRS-2693 6850:MRS-2690 6845:MRS-2365 6755:5-Br-UDP 6697:TC-P 262 6637:Puerarin 6572:MRS-2159 6547:isoPPADS 6465:A-839977 6460:A-804598 6455:A-740003 6450:A-438079 6445:A-317491 6415:MRS-2219 6278:VUF-5574 6223:PSB-1115 6168:MRS-3777 6163:MRS-1754 6158:MRS-1706 6153:MRS-1334 6148:MRS-1220 6138:KF-26777 6083:CVT-6883 6058:CGH-2466 6043:Caffeine 5935:LUF-5845 5930:LUF-5835 5925:GR 79236 5880:ATL-146e 5762:Receptor 5576:Atropine 5502:Atenolol 5482:Pindolol 5459:class II 5445:agonists 5442:Receptor 5405:class IV 5170:Ajmaline 4882:c-di-AMP 4877:c-di-GMP 4662:Cytidine 4598:Cytosine 4571:Xanthine 4479:Category 4440:(CCrISP) 4284:Naloxone 4274:Dopamine 4269:Atropine 3930:-derived 3876:-derived 3857:instead. 3812:Oleamide 3743:-derived 3724:instead. 3581:Dopamine 3392:Agmatine 3369:-derived 3229:15772334 3194:14746372 3084:35575450 3035:24183218 3007:22020741 2966:12289511 2958:19239555 2922:11248116 2863:12151508 2814:21044428 2787:18846036 2738:18461129 2698:PLOS ONE 2679:24590073 2622:15388457 2573:19918064 2404:21917810 2355:23601906 2306:31878283 2255:30513816 2204:14698282 2169:18758473 2120:18311158 2038:34019396 1958:20164566 1907:32166015 1854:10 April 1760:30725774 1730:19000353 1703:21575090 1654:16525141 1619:44107679 1611:29848236 1481:See also 1418:cannabis 1407:insomnia 1381:in male 1355:dopamine 1348:Caffeine 1252:Research 1172:receptor 1144:appetite 1030:ischemia 1021:ischemic 950:receptor 942:Caffeine 923:caffeine 908:Caffeine 863:diazepam 825:thallium 813:asystole 719:Adenosyl 663:) is an 644:(verify) 346:DrugBank 129:ATC code 98:category 8377:Purines 8300:YIL-781 8295:JMV2959 8147:Ghrelin 7977:SRIF-28 7972:SRIF-14 7630:rhubarb 7623:Others: 7601:Uridine 7571:Inosine 7541:Guanine 7491:Adenine 7241:Ethanol 7226:Dilazep 7178:MeThPmR 7085:Suramin 6990:C1330-7 6835:INS-365 6714:TNP-ATP 6692:Suramin 6490:Calcium 6218:PSB-788 6213:PSB-603 6028:ATL-444 5800:Adenine 5783:adenine 5768:ligands 5668:Ouabain 5663:Digoxin 5594:Digoxin 5533:agonist 5507:Esmolol 5477:Nadolol 5464:Phase 4 5410:Phase 4 5385:Sotalol 5327:Phase 3 5269:Phase 0 5240:enteral 5216:Phase 3 5161:Phase 3 5157:Phase 0 5141:class I 4672:Inosine 4652:Uridine 4593:Thymine 4561:Guanine 4556:Adenine 4491:Outline 4416:(ACoRN) 4362:Courses 3928:Vitamin 3822:RVD-HpĪ± 3777:AA-5-HT 3524:Taurine 3509:Proline 3499:Glycine 3442:Proline 3412:Glycine 3319:1884445 3278:9576114 3075:9541543 2890:Bibcode 2854:6758129 2778:2579671 2729:2329854 2706:Bibcode 2670:7095208 2649:Bibcode 2564:2787148 2541:Bibcode 2514:8020339 2395:3328085 2346:3674206 2297:7016859 2246:6321150 2160:2568887 2111:2268070 2003:7752065 1898:7052475 1827:1514488 1695:6376597 1346:(CNS). 1305:Marburg 1297:BCX4430 1281:viremia 1275:of the 1269:NITD008 1257:Viruses 1208:de novo 1162:in the 1138:of the 1136:agonist 1070:, and A 1026:hypoxia 964:Common 887:elderly 879:hypoxia 796:(e.g., 784:(e.g., 727:5'-dAdo 669:adenine 560:267.245 522:Formula 355:DB00640 301:PubChem 290:58-61-7 145:) 139: ( 137:C01EB10 23:adenine 8172:GHRP-6 8167:GHRP-5 8162:GHRP-4 8157:GHRP-3 8152:GHRP-1 7982:TT-232 7952:RC-160 7887:CH-275 7596:Uracil 7591:Ribose 7481:Others 7431:Others 7303:Enzyme 7050:NF-340 7045:NF-157 6945:A3P5PS 6875:NF-546 6597:NF-449 6592:NF-279 6587:NF-157 6582:NF-110 6577:NF-023 6510:Emodin 6505:Copper 6470:AF-353 6440:5-BDBD 6400:HT-AMP 6208:PSB-36 6203:PSB-11 6198:PSB-10 5686:WHO-EM 5370:E-4031 5159:ā†’ and 4588:Uracil 4551:Purine 4434:(ALSO) 4428:(PALS) 4422:(PBLS) 4404:(ATLS) 4398:(ACLS) 4154:Triage 3893:system 3767:2-ALPI 3688:Others 3519:Serine 3447:Serine 3317:  3276:  3235:  3227:  3192:  3149:  3082:  3072:  3033:  3005:  2964:  2956:  2920:  2910:  2861:  2851:  2812:  2785:  2775:  2736:  2726:  2677:  2667:  2641:Nature 2620:  2613:521892 2610:  2571:  2561:  2512:  2482:  2454:KIMITO 2432:  2402:  2392:  2353:  2343:  2304:  2294:  2253:  2243:  2202:  2167:  2157:  2118:  2108:  2067:  2044:  2036:  2001:  1956:  1905:  1895:  1825:  1787:  1758:  1728:  1701:  1693:  1652:  1617:  1609:  1556:  1531:  1074:) are 1009:, and 973:Asthma 935:purine 921:(e.g. 838:Dosage 673:ribose 658:symbol 593:SMILES 446:ChEMBL 415:C00212 8311:IGF-1 7692:IGF-1 7251:NBMPR 7060:PPADS 6985:BzATP 6950:AMPĪ±S 6930:UTPĪ³S 6900:UDPĪ²S 6800:ATPĪ³S 6780:ADPĪ²S 6664:Ro 51 6627:PPNDS 6622:PPADS 6562:KN-62 6557:KN-04 6375:BzATP 6370:ATPĪ³S 6098:DPCPX 4892:cGAMP 4887:cADPR 4410:(NRP) 4392:(BLS) 4381:(CPR) 4252:Drugs 4239:(OPA) 4233:(NPA) 4174:(BVM) 3802:NAGly 3741:Lipid 3576:6-OHM 3468:GABOB 3237:71178 3233:S2CID 3172:Sleep 3127:(PDF) 2962:S2CID 2913:30691 2274:Cells 2042:S2CID 1844:(PDF) 1699:S2CID 1615:S2CID 1432:sleep 1389:Sleep 1301:Ebola 1110:and A 875:shock 792:) or 782:atria 613:InChI 569:JSmol 426:ChEBI 375:54923 315:60961 8325:here 8323:See 8062:GHRH 8028:GHRH 7866:GHIH 7851:GHBP 7694:axis 7277:PMAT 7199:ENTs 7136:CNTs 7075:RB-2 7010:Ip5I 6955:Ap4A 6920:Up3U 6810:dATP 6785:Ap3A 6719:Zinc 6669:RO-3 6654:RB-2 6542:Ip5I 6430:Zinc 6360:Ap5A 6355:Ap4A 6123:IBMX 6093:DMPX 5905:CCPA 5448:and 5123:C01B 5073:dXTP 5068:dITP 5063:dCTP 5058:dUTP 5053:dTTP 5048:dGTP 5043:dATP 5010:mUTP 4974:dCDP 4969:dUDP 4964:dTDP 4959:dGDP 4954:dADP 4926:mUDP 4872:cGMP 4867:cAMP 4849:dXMP 4844:dIMP 4839:dCMP 4834:dUMP 4829:dTMP 4824:dGMP 4819:dAMP 4781:mUMP 4212:(IV) 4206:(IO) 3855:here 3853:See 3797:NADA 3772:2-OG 3757:2-AG 3722:here 3720:See 3463:GABA 3437:NAAG 3422:GSSG 3417:GSNO 3315:PMID 3274:PMID 3225:PMID 3190:PMID 3147:ISBN 3080:PMID 3031:PMID 3003:PMID 2954:PMID 2918:PMID 2859:PMID 2810:PMID 2783:PMID 2734:PMID 2675:PMID 2618:PMID 2569:PMID 2510:PMID 2480:ISBN 2430:ISBN 2400:PMID 2351:PMID 2302:PMID 2251:PMID 2200:PMID 2165:PMID 2116:PMID 2065:ISBN 2034:PMID 1999:PMID 1954:PMID 1903:PMID 1856:2023 1823:PMID 1785:ISBN 1756:PMID 1726:PMID 1718:CJEM 1691:PMID 1650:PMID 1607:PMID 1554:ISBN 1529:ISBN 1436:rats 1373:Hair 1357:and 1303:and 1213:via 788:and 406:KEGG 386:UNII 335:2844 177:data 78:AHFS 8108:GHS 7616:UTP 7611:UDP 7606:UMP 7586:ITP 7581:IDP 7576:IMP 7561:GTP 7556:GDP 7551:GMP 7536:CTP 7531:CDP 7526:CMP 7511:ATP 7506:ADP 7501:AMP 7100:UDP 7055:PIT 6980:ATP 6925:UTP 6895:UDP 6830:ITP 6825:IDP 6805:CTP 6795:ATP 6775:ADP 6729:P2Y 6537:HMA 6485:BBG 6425:UTP 6395:GTP 6385:CTP 6365:ATP 6350:AMP 6345:ADP 6314:ATP 6308:P2X 6078:CPX 5885:ATP 5870:AMP 5865:ADP 5851:5'- 5466:ā†’, 5412:ā†’, 5329:ā†’, 5030:XTP 5025:ITP 5020:CTP 5015:UTP 5005:GTP 5000:ATP 4936:CDP 4931:UDP 4921:GDP 4916:ADP 4801:XMP 4796:IMP 4791:CMP 4786:UMP 4776:GMP 4771:AMP 4192:ICD 4187:AED 3910:ATP 3905:AMP 3900:ADP 3827:SEA 3817:PEA 3807:OEA 3792:LPI 3787:DEA 3542:GHB 3473:GHB 3432:NAA 3305:doi 3264:doi 3217:doi 3213:288 3180:doi 3139:doi 3070:PMC 3062:doi 2993:doi 2946:doi 2908:PMC 2898:doi 2849:PMC 2841:doi 2773:PMC 2765:doi 2761:155 2724:PMC 2714:doi 2665:PMC 2657:doi 2645:508 2608:PMC 2600:doi 2559:PMC 2549:doi 2537:106 2390:PMC 2382:doi 2341:PMC 2333:doi 2292:PMC 2282:doi 2241:PMC 2231:doi 2192:doi 2155:PMC 2147:doi 2106:PMC 2098:doi 2094:153 2026:doi 1995:273 1944:hdl 1934:doi 1893:PMC 1883:doi 1815:doi 1811:124 1681:doi 1642:doi 1638:354 1597:hdl 1587:doi 1521:doi 1461:of 1434:in 1088:i/o 1066:, A 1062:, A 1040:or 1016:). 725:or 723:Ado 697:DNA 689:RNA 471:EPA 305:CID 142:WHO 8343:: 8256:; 8214:; 7709:GH 7688:GH 7321:XO 6682:, 6293:P2 5810:P1 5779:P0 5699:: 5592:: 5574:: 5271:ā†’) 5226:IV 5218:ā†) 5163:ā†’) 4364:/ 4030:O) 3982:S) 3313:. 3301:84 3299:. 3295:. 3272:. 3260:31 3258:. 3254:. 3231:. 3223:. 3211:. 3188:. 3176:26 3174:. 3170:. 3145:. 3133:. 3129:. 3100:. 3078:. 3068:. 3058:31 3056:. 3052:. 3027:21 3025:. 3001:. 2989:29 2987:. 2983:. 2960:. 2952:. 2942:35 2940:. 2916:. 2906:. 2896:. 2886:98 2884:. 2880:. 2857:. 2847:. 2837:22 2835:. 2831:. 2806:28 2804:. 2781:. 2771:. 2759:. 2755:. 2732:. 2722:. 2712:. 2700:. 2696:. 2673:. 2663:. 2655:. 2643:. 2639:. 2616:. 2606:. 2596:48 2594:. 2590:. 2567:. 2557:. 2547:. 2535:. 2531:. 2506:36 2504:. 2452:. 2412:^ 2398:. 2388:. 2378:31 2376:. 2372:. 2349:. 2339:. 2329:19 2327:. 2323:. 2300:. 2290:. 2276:. 2272:. 2249:. 2239:. 2227:19 2225:. 2221:. 2198:. 2188:25 2186:. 2163:. 2153:. 2141:. 2137:. 2114:. 2104:. 2092:. 2088:. 2040:. 2032:. 2022:64 2020:. 1993:. 1952:. 1942:. 1930:20 1928:. 1924:. 1901:. 1891:. 1879:10 1877:. 1873:. 1846:. 1821:. 1809:. 1750:. 1738:^ 1722:10 1720:. 1697:. 1689:. 1675:. 1671:. 1648:. 1636:. 1613:. 1605:. 1595:. 1583:98 1581:. 1577:. 1527:. 1477:. 1367:2A 1321:2A 1295:. 1242:. 1108:2B 1068:2B 1064:2A 1044:. 1034:2A 1028:, 1006:2B 1002:, 999:2A 995:, 877:, 873:, 869:, 715:. 536:13 530:10 263:,5 259:,4 255:,3 251:(2 197:No 8288:D 8286:( 7690:/ 7679:e 7672:t 7665:v 7632:) 7628:( 7311:) 7307:( 7126:) 7122:( 6710:) 6704:( 6688:) 6676:( 6645:) 6639:( 6518:) 6512:( 6320:) 6311:( 6300:) 6296:( 5941:N 5853:N 5829:N 5817:) 5813:( 5785:) 5781:( 5770:) 5766:( 5743:e 5736:t 5729:v 5563:2 5561:M 5531:1 5529:A 5470:) 5462:( 5416:) 5408:( 5333:) 5325:( 5148:) 5144:( 5125:) 5121:( 5111:e 5104:t 5097:v 4678:N 4526:e 4519:t 4512:v 4318:) 4314:( 4194:) 4185:( 4077:e 4070:t 4063:v 4039:) 4037:2 4028:2 4016:) 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Index

adenine


Trade names
AHFS
Drugs.com
Monograph
Pregnancy
category

Routes of
administration

ATC code
C01EB10
WHO
Legal status
Pharmacokinetic
Bioavailability
Protein binding
Metabolism
Elimination half-life
Excretion
IUPAC name
CAS Number
58-61-7
PubChem
60961
IUPHAR/BPS
2844
DrugBank
DB00640
ChemSpider
54923

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