42:
2577:
1115:
713:
955 patients were divided into three groups in a 1:1:1 ratio. Each group was injected subcutaneously monthly with 0, 70 or 140 mg erenumab over a period of 6 months. The results were measured as mean monthly migraine days in months 4, 5, and 6. At baseline the patients experienced between 4 and
1989:
1111:
1982:
1975:
758:
approved the medication for the preventive treatment of migraine in adults in May 2018. It was the first CGRPR antagonist to be approved. It was approved for medical use in the
European Union on 26 July 2018.
714:
14 migraine days per month with an average of 8.3. The medication significantly reduced the number of migraine days per month by 3.2 in the 70-mg group and 3.7 in the 140-mg group, versus 1.8 in the
2602:
1340:
1307:
1112:"Amgen Presents First-Of-Its-Kind Data At AAN Annual Meeting Reinforcing Robust And Consistent Efficacy Of Aimovig (erenumab) For Migraine Patients With Multiple Treatment Failures"
1275:
832:
218:
1902:
1652:
1427:
1086:
871:
743:
1180:
116:
1212:
1384:
59:
647:
539:
86:
1420:
1329:
1297:
2531:
1933:
2617:
1267:
915:
822:
1493:
1413:
768:
1075:
863:
1862:
1449:
248:
148:
2607:
1967:
800:
739:
1177:
998:
2062:
1336:
755:
562:
405:
2597:
2548:
1998:
1950:
1245:
167:
2567:
1519:
1202:
772:
1365:
1082:
909:
706:
1369:
2187:
2182:
1800:
2536:
1938:
1714:
1705:
602:
204:
2443:
659:
547:
454:
211:
683:
565:. In 2020, it was the 234th most commonly prescribed medication in the United States, with more than 1
1755:
670:
concentrations are reached after four to six days. Like other proteins, the substance is degraded by
625:. It is expected to generally have a low potential for interactions because it is not metabolized by
331:
1869:
1489:
1475:
643:
349:
69:
52:
2419:
2321:
2220:
2091:
1207:
944:
Goadsby PJ, Reuter U, Hallström Y, Broessner G, Bonner JH, Zhang F, et al. (November 2017).
178:
1370:"International Nonproprietary Names for Pharmaceutical Substances (INN). Proposed INN: List 115"
1504:
1480:
1436:
1160:
967:
614:
279:
262:
98:
358:
2228:
1150:
957:
904:
470:
301:
414:
2581:
1240:
1184:
663:
626:
561:, was approved in May 2018, and was the first CGRPR antagonist to be approved by the U.S.
319:
309:
746:
rejected the drug on the basis that its cost-effectiveness was not sufficiently proven.
2612:
2542:
2197:
1944:
1828:
710:
2591:
2513:
2472:
2282:
2116:
1841:
1836:
1813:
1808:
1765:
1618:
827:
140:
126:
41:
2508:
2399:
2394:
2379:
2336:
2277:
2267:
2252:
2247:
1892:
1887:
1773:
1628:
1575:
1555:
1509:
1440:
1405:
1302:
667:
618:
590:
231:
226:
1020:
2492:
2458:
2424:
2414:
2389:
2292:
2287:
2242:
2237:
2233:
2210:
2161:
2121:
2048:
1877:
1778:
1747:
1737:
1686:
1570:
1565:
1560:
1540:
1045:
792:
671:
622:
324:
134:
1155:
1138:
2487:
2404:
2384:
2363:
2358:
2326:
2262:
2257:
2151:
2146:
2136:
2131:
2126:
2111:
2106:
2077:
2043:
1915:
1846:
1818:
1727:
1722:
1670:
1665:
1660:
1623:
1598:
1550:
1545:
1485:
988:
679:
535:
509:
389:
989:"FDA Approves First-in-Class Drug Erenumab (Aimovig) for Migraine Prevention"
864:"Aimovig- erenumab-aooe injection Aimovig- erenumab-aooe injection, solution"
2429:
2409:
2353:
2341:
2331:
2306:
2272:
2205:
2166:
2156:
2141:
2027:
2022:
1910:
1851:
1790:
1732:
1638:
1633:
1593:
1458:
120:
1330:"Statement On A Nonproprietary Name Adopted By The USAN Council - Erenumab"
1235:
1164:
971:
962:
945:
1691:
1499:
1467:
993:
699:
594:
578:
558:
543:
369:
162:
33:
378:
1783:
1532:
715:
675:
81:
17:
1866:
445:
434:
1585:
1268:"New migraine drug not cost-effective NICE says in draft guidance"
695:
598:
554:
74:
2007:
425:
285:
1971:
1409:
273:
157:
2001:
for bone, musculoskeletal, circulatory, and neurologic systems
1178:"Erenumab to prevent migraine: results from phase III STRIBE"
189:
1203:"F.D.A. Approves First Drug Designed to Prevent Migraines"
1298:"First drug to prevent chronic migraines approved by EU"
257:
946:"A Controlled Trial of Erenumab for Episodic Migraine"
2565:
2603:
Calcitonin gene-related peptide receptor antagonists
738:
In the United
Kingdom, Erenumab was approved by the
2501:
2480:
2471:
2451:
2442:
2372:
2314:
2305:
2219:
2196:
2175:
2099:
2090:
2070:
2061:
2036:
2015:
2006:
1901:
1860:
1827:
1799:
1764:
1746:
1713:
1704:
1679:
1651:
1611:
1584:
1531:
1518:
1466:
1457:
1448:
858:
856:
854:
852:
850:
508:
469:
464:
444:
424:
404:
388:
368:
348:
343:
330:
318:
308:
300:
247:
242:
217:
203:
177:
147:
133:
115:
107:
97:
92:
80:
68:
58:
51:
744:National Institute for Health and Care Excellence
1236:"'Life-changing' migraine drug rejected for NHS"
357:
899:
897:
895:
893:
891:
889:
731:As of 2018, the list price was reported to be
1983:
1421:
823:"Summary Basis of Decision (SBD) for Aimovig"
8:
1139:"CGRP Antibodies as Prophylaxis in Migraine"
577:Erenumab is indicated for the prevention of
166:
32:
293:In general: ℞ (Prescription only)
2477:
2448:
2311:
2096:
2067:
2012:
1990:
1976:
1968:
1710:
1528:
1463:
1454:
1428:
1414:
1406:
983:
981:
40:
1154:
961:
939:
937:
935:
933:
793:"Erenumab (Aimovig) Use During Pregnancy"
413:
648:calcitonin gene-related peptide receptor
613:Erenumab was shown not to interact with
540:calcitonin gene-related peptide receptor
2572:
1114:(Press release). Amgen. 17 April 2018.
784:
601:, as well as mild and mostly transient
377:
139:
46:A standard 70mg/mL Aimovig autoinjector
1310:from the original on 19 September 2018
1070:
1068:
1066:
1001:from the original on 25 September 2019
31:
1118:from the original on 11 November 2020
1076:"Aimovig: EPAR - Product Information"
803:from the original on 29 November 2020
453:
125:
7:
1390:from the original on 5 February 2018
1346:from the original on 4 November 2018
1278:from the original on 1 November 2020
918:from the original on 17 October 2020
230:
1092:from the original on 6 October 2018
950:The New England Journal of Medicine
433:
1046:"Erenumab - Drug Usage Statistics"
25:
1248:from the original on 31 July 2021
1234:Gallagher J (26 September 2019).
769:international nonproprietary name
553:Erenumab, which was developed by
2575:
1215:from the original on 11 May 2020
874:from the original on 5 July 2022
835:from the original on 31 May 2022
662:, the erenumab has an estimated
487:
481:
603:reactions at the injection site
542:(CGRPR) for the prevention of
499:
493:
475:
1:
1137:Edvinsson L (December 2018).
740:Scottish Medicines Consortium
1337:American Medical Association
756:Food and Drug Administration
563:Food and Drug Administration
530:, sold under the brand name
2618:Drugs developed by Novartis
2634:
1156:10.1016/j.cell.2018.11.049
773:United States Adopted Name
694:Erenumab was developed by
642:Erenumab is a fully human
465:Chemical and physical data
2526:
1928:
1801:Tricyclic antidepressants
1366:World Health Organization
1083:European Medicines Agency
910:European Medicines Agency
39:
1715:Calcium channel blockers
1494:+chlorcyclizine/caffeine
1201:Kolata G (17 May 2018).
1126:– via PR Newswire.
589:Common side effects are
546:. It is administered by
569:million prescriptions.
2444:Angiogenesis inhibitor
1183:13 August 2018 at the
660:subcutaneous injection
548:subcutaneous injection
212:Subcutaneous injection
111:AMG-334, erenumab-aooe
2608:Monoclonal antibodies
1021:"The Top 300 of 2020"
963:10.1056/NEJMoa1705848
684:elimination half-life
621:or the migraine drug
1756:Flumedroxone acetate
1377:WHO Drug Information
1339:. 24 November 2015.
698:in conjunction with
1476:Dihydroergocryptine
1191:, 14 December 2017.
831:. 23 October 2014.
722:Society and culture
644:monoclonal antibody
638:Mechanism of action
53:Monoclonal antibody
36:
2598:Antimigraine drugs
2553:Never to phase III
2322:Anti-amyloid drugs
1955:Never to phase III
1903:CGRP-R antagonists
1653:CGRP-R antagonists
1450:Analgesic/abortive
1208:The New York Times
870:. 19 August 2022.
754:The United States
2563:
2562:
2522:
2521:
2467:
2466:
2438:
2437:
2301:
2300:
2086:
2085:
2057:
2056:
1965:
1964:
1924:
1923:
1700:
1699:
1647:
1646:
1607:
1606:
1505:Methylergometrine
1481:Dihydroergotamine
1085:. 8 August 2018.
956:(22): 2123–2132.
799:. 17 April 2019.
538:which blocks the
525:
524:
289:
277:
260:
193:
160:
27:Chemical compound
16:(Redirected from
2625:
2580:
2579:
2578:
2571:
2478:
2449:
2312:
2229:Alacizumab pegol
2097:
2068:
2013:
1992:
1985:
1978:
1969:
1711:
1529:
1464:
1455:
1430:
1423:
1416:
1407:
1400:
1399:
1397:
1395:
1389:
1374:
1362:
1356:
1355:
1353:
1351:
1345:
1334:
1326:
1320:
1319:
1317:
1315:
1306:. 31 July 2018.
1294:
1288:
1287:
1285:
1283:
1264:
1258:
1257:
1255:
1253:
1231:
1225:
1224:
1222:
1220:
1198:
1192:
1175:
1169:
1168:
1158:
1134:
1128:
1127:
1125:
1123:
1108:
1102:
1101:
1099:
1097:
1091:
1080:
1072:
1061:
1060:
1058:
1056:
1042:
1036:
1035:
1033:
1031:
1017:
1011:
1010:
1008:
1006:
985:
976:
975:
965:
941:
928:
927:
925:
923:
901:
884:
883:
881:
879:
860:
845:
844:
842:
840:
819:
813:
812:
810:
808:
789:
767:Erenumab is the
734:
666:of 82%. Highest
654:Pharmacokinetics
615:ethinylestradiol
568:
520:
518:
501:
495:
489:
483:
477:
457:
437:
417:
381:
361:
335:
287:
284:
275:
272:
268:
259:
256:
234:
191:
188:
170:
159:
156:
143:
129:
44:
37:
35:
21:
2633:
2632:
2628:
2627:
2626:
2624:
2623:
2622:
2588:
2587:
2586:
2576:
2574:
2566:
2564:
2559:
2558:
2543:Clinical trials
2518:
2497:
2463:
2434:
2368:
2297:
2215:
2192:
2171:
2082:
2063:Musculoskeletal
2053:
2032:
2002:
1996:
1966:
1961:
1960:
1945:Clinical trials
1920:
1897:
1856:
1829:Anticonvulsants
1823:
1795:
1760:
1742:
1696:
1675:
1643:
1603:
1580:
1523:
1514:
1444:
1434:
1404:
1403:
1393:
1391:
1387:
1372:
1364:
1363:
1359:
1349:
1347:
1343:
1332:
1328:
1327:
1323:
1313:
1311:
1296:
1295:
1291:
1281:
1279:
1266:
1265:
1261:
1251:
1249:
1241:BBC News Online
1233:
1232:
1228:
1218:
1216:
1200:
1199:
1195:
1185:Wayback Machine
1176:
1172:
1136:
1135:
1131:
1121:
1119:
1110:
1109:
1105:
1095:
1093:
1089:
1078:
1074:
1073:
1064:
1054:
1052:
1044:
1043:
1039:
1029:
1027:
1019:
1018:
1014:
1004:
1002:
997:. 17 May 2018.
987:
986:
979:
943:
942:
931:
921:
919:
903:
902:
887:
877:
875:
862:
861:
848:
838:
836:
821:
820:
816:
806:
804:
791:
790:
786:
781:
765:
752:
732:
729:
724:
692:
664:bioavailability
656:
640:
635:
627:cytochrome P450
611:
587:
575:
566:
516:
514:
504:
498:
492:
486:
480:
460:
440:
420:
400:
384:
364:
333:
314:82% (estimated)
310:Bioavailability
302:Pharmacokinetic
296:
266:
238:
206:
199:
180:
173:
47:
28:
23:
22:
15:
12:
11:
5:
2631:
2629:
2621:
2620:
2615:
2610:
2605:
2600:
2590:
2589:
2585:
2584:
2561:
2560:
2557:
2556:
2555:
2554:
2551:
2540:
2534:
2528:
2527:
2524:
2523:
2520:
2519:
2517:
2516:
2511:
2505:
2503:
2499:
2498:
2496:
2495:
2490:
2484:
2482:
2475:
2469:
2468:
2465:
2464:
2462:
2461:
2455:
2453:
2446:
2440:
2439:
2436:
2435:
2433:
2432:
2427:
2422:
2417:
2412:
2407:
2402:
2397:
2392:
2387:
2382:
2376:
2374:
2370:
2369:
2367:
2366:
2361:
2356:
2351:
2346:
2345:
2344:
2339:
2334:
2329:
2318:
2316:
2309:
2303:
2302:
2299:
2298:
2296:
2295:
2290:
2285:
2280:
2275:
2270:
2265:
2260:
2255:
2250:
2245:
2240:
2231:
2225:
2223:
2217:
2216:
2214:
2213:
2208:
2202:
2200:
2194:
2193:
2191:
2190:
2185:
2179:
2177:
2173:
2172:
2170:
2169:
2164:
2159:
2154:
2149:
2144:
2139:
2134:
2129:
2124:
2119:
2114:
2109:
2103:
2101:
2094:
2088:
2087:
2084:
2083:
2081:
2080:
2074:
2072:
2065:
2059:
2058:
2055:
2054:
2052:
2051:
2046:
2040:
2038:
2034:
2033:
2031:
2030:
2025:
2019:
2017:
2010:
2004:
2003:
1997:
1995:
1994:
1987:
1980:
1972:
1963:
1962:
1959:
1958:
1957:
1956:
1953:
1942:
1936:
1930:
1929:
1926:
1925:
1922:
1921:
1919:
1918:
1913:
1907:
1905:
1899:
1898:
1896:
1895:
1890:
1885:
1880:
1874:
1872:
1858:
1857:
1855:
1854:
1849:
1844:
1839:
1833:
1831:
1825:
1824:
1822:
1821:
1816:
1811:
1805:
1803:
1797:
1796:
1794:
1793:
1788:
1787:
1786:
1781:
1770:
1768:
1766:Sympatholytics
1762:
1761:
1759:
1758:
1752:
1750:
1744:
1743:
1741:
1740:
1735:
1730:
1725:
1719:
1717:
1708:
1702:
1701:
1698:
1697:
1695:
1694:
1689:
1683:
1681:
1677:
1676:
1674:
1673:
1668:
1663:
1657:
1655:
1649:
1648:
1645:
1644:
1642:
1641:
1636:
1631:
1626:
1621:
1615:
1613:
1609:
1608:
1605:
1604:
1602:
1601:
1596:
1590:
1588:
1582:
1581:
1579:
1578:
1573:
1568:
1563:
1558:
1553:
1548:
1543:
1537:
1535:
1526:
1521:
1516:
1515:
1513:
1512:
1507:
1502:
1497:
1483:
1478:
1472:
1470:
1461:
1452:
1446:
1445:
1439:preparations (
1435:
1433:
1432:
1425:
1418:
1410:
1402:
1401:
1357:
1321:
1289:
1259:
1226:
1193:
1170:
1129:
1103:
1062:
1037:
1012:
977:
929:
905:"Aimovig EPAR"
885:
846:
814:
783:
782:
780:
777:
764:
761:
751:
748:
728:
725:
723:
720:
718:(0-mg) group.
711:clinical trial
691:
688:
655:
652:
639:
636:
634:
631:
610:
607:
586:
583:
574:
571:
523:
522:
512:
506:
505:
502:
496:
490:
484:
478:
473:
467:
466:
462:
461:
459:
458:
450:
448:
442:
441:
439:
438:
430:
428:
422:
421:
419:
418:
410:
408:
402:
401:
399:
398:
394:
392:
386:
385:
383:
382:
374:
372:
366:
365:
363:
362:
354:
352:
346:
345:
341:
340:
337:
328:
327:
322:
316:
315:
312:
306:
305:
298:
297:
295:
294:
291:
282:
270:
253:
251:
245:
244:
240:
239:
237:
236:
223:
221:
215:
214:
209:
207:administration
201:
200:
198:
197:
195:
185:
183:
175:
174:
172:
171:
153:
151:
145:
144:
137:
131:
130:
123:
113:
112:
109:
105:
104:
101:
95:
94:
90:
89:
84:
78:
77:
72:
66:
65:
64:Whole antibody
62:
56:
55:
49:
48:
45:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
2630:
2619:
2616:
2614:
2611:
2609:
2606:
2604:
2601:
2599:
2596:
2595:
2593:
2583:
2573:
2569:
2552:
2550:
2547:
2546:
2544:
2541:
2538:
2535:
2533:
2530:
2529:
2525:
2515:
2514:Landogrozumab
2512:
2510:
2507:
2506:
2504:
2500:
2494:
2491:
2489:
2486:
2485:
2483:
2479:
2476:
2474:
2473:Growth factor
2470:
2460:
2457:
2456:
2454:
2450:
2447:
2445:
2441:
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2319:
2317:
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2308:
2304:
2294:
2291:
2289:
2286:
2284:
2283:Ralpancizumab
2281:
2279:
2276:
2274:
2271:
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2266:
2264:
2261:
2259:
2256:
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2145:
2143:
2140:
2138:
2135:
2133:
2130:
2128:
2125:
2123:
2120:
2118:
2117:Ascrinvacumab
2115:
2113:
2110:
2108:
2105:
2104:
2102:
2098:
2095:
2093:
2089:
2079:
2076:
2075:
2073:
2069:
2066:
2064:
2060:
2050:
2047:
2045:
2042:
2041:
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2035:
2029:
2026:
2024:
2021:
2020:
2018:
2014:
2011:
2009:
2005:
2000:
1993:
1988:
1986:
1981:
1979:
1974:
1973:
1970:
1954:
1952:
1949:
1948:
1946:
1943:
1940:
1937:
1935:
1932:
1931:
1927:
1917:
1914:
1912:
1909:
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1900:
1894:
1891:
1889:
1886:
1884:
1881:
1879:
1876:
1875:
1873:
1871:
1868:
1864:
1859:
1853:
1850:
1848:
1845:
1843:
1842:Oxcarbazepine
1840:
1838:
1837:Carbamazepine
1835:
1834:
1832:
1830:
1826:
1820:
1817:
1815:
1814:Nortriptyline
1812:
1810:
1809:Amitriptyline
1807:
1806:
1804:
1802:
1798:
1792:
1789:
1785:
1782:
1780:
1777:
1776:
1775:
1774:Beta blockers
1772:
1771:
1769:
1767:
1763:
1757:
1754:
1753:
1751:
1749:
1745:
1739:
1736:
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1726:
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1707:
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1637:
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1632:
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1627:
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1622:
1620:
1619:Dimetotiazine
1617:
1616:
1614:
1610:
1600:
1597:
1595:
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1501:
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1491:
1487:
1484:
1482:
1479:
1477:
1474:
1473:
1471:
1469:
1465:
1462:
1460:
1459:Serotonergics
1456:
1453:
1451:
1447:
1442:
1438:
1431:
1426:
1424:
1419:
1417:
1412:
1411:
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1386:
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1371:
1367:
1361:
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1309:
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1299:
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1242:
1237:
1230:
1227:
1214:
1210:
1209:
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1197:
1194:
1190:
1186:
1182:
1179:
1174:
1171:
1166:
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1157:
1152:
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1133:
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1113:
1107:
1104:
1088:
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1051:
1047:
1041:
1038:
1026:
1022:
1016:
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1000:
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969:
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955:
951:
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940:
938:
936:
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930:
917:
913:
911:
906:
900:
898:
896:
894:
892:
890:
886:
873:
869:
865:
859:
857:
855:
853:
851:
847:
834:
830:
829:
828:Health Canada
824:
818:
815:
802:
798:
794:
788:
785:
778:
776:
774:
770:
762:
760:
757:
749:
747:
745:
741:
736:
726:
721:
719:
717:
712:
708:
703:
701:
697:
689:
687:
685:
681:
677:
673:
669:
665:
661:
653:
651:
649:
646:blocking the
645:
637:
632:
630:
628:
624:
620:
616:
608:
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604:
600:
596:
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580:
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560:
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551:
549:
545:
541:
537:
533:
529:
513:
511:
507:
474:
472:
468:
463:
456:
455:ChEMBL3833329
452:
451:
449:
447:
443:
436:
432:
431:
429:
427:
423:
416:
412:
411:
409:
407:
403:
396:
395:
393:
391:
387:
380:
376:
375:
373:
371:
367:
360:
356:
355:
353:
351:
347:
342:
338:
336:
329:
326:
323:
321:
317:
313:
311:
307:
303:
299:
292:
290: Rx-only
283:
281:
271:
264:
255:
254:
252:
250:
246:
241:
233:
228:
225:
224:
222:
220:
216:
213:
210:
208:
202:
196:
187:
186:
184:
182:
176:
169:
164:
155:
154:
152:
150:
146:
142:
138:
136:
132:
128:
124:
122:
118:
114:
110:
106:
102:
100:
96:
93:Clinical data
91:
88:
85:
83:
79:
76:
73:
71:
67:
63:
61:
57:
54:
50:
43:
38:
30:
19:
2509:Domagrozumab
2400:Galcanezumab
2395:Fremanezumab
2380:Bapineuzumab
2348:
2337:Gantenerumab
2278:Idarucizumab
2268:Etaracizumab
2253:Caplacizumab
2248:Brolucizumab
1893:Galcanezumab
1888:Fremanezumab
1882:
1748:Progestogens
1706:Prophylactic
1629:Iprazochrome
1576:Zolmitriptan
1556:Frovatriptan
1510:Methysergide
1437:Antimigraine
1394:30 September
1392:. Retrieved
1380:
1376:
1360:
1348:. Retrieved
1324:
1314:19 September
1312:. Retrieved
1303:The Guardian
1301:
1292:
1282:26 September
1280:. Retrieved
1271:
1262:
1252:26 September
1250:. Retrieved
1239:
1229:
1219:26 September
1217:. Retrieved
1206:
1196:
1189:Pharma World
1188:
1173:
1146:
1142:
1132:
1122:29 September
1120:. Retrieved
1106:
1094:. Retrieved
1053:. Retrieved
1049:
1040:
1028:. Retrieved
1024:
1015:
1003:. Retrieved
992:
953:
949:
920:. Retrieved
908:
878:29 September
876:. Retrieved
867:
837:. Retrieved
826:
817:
805:. Retrieved
796:
787:
766:
753:
750:Legal status
737:
730:
704:
693:
686:of 28 days.
682:. It has an
668:blood plasma
657:
641:
633:Pharmacology
619:norgestimate
612:
609:Interactions
591:constipation
588:
585:Side effects
576:
573:Medical uses
552:
531:
527:
526:
359:1582205-90-0
332:Elimination
249:Legal status
243:Legal status
149:License data
29:
2539:from market
2493:Trevogrumab
2459:Ranibizumab
2425:Solanezumab
2420:Semorinemab
2415:Refanezumab
2390:Eptinezumab
2293:Vanucizumab
2288:Tadocizumab
2243:Bococizumab
2238:Ranibizumab
2234:Bevacizumab
2211:Volociximab
2162:Ramucirumab
2122:Bentracimab
2092:Circulatory
2049:Romosozumab
1999:Monoclonals
1941:from market
1878:Eptinezumab
1779:Propranolol
1738:Flunarizine
1687:Paracetamol
1571:Sumatriptan
1566:Rizatriptan
1561:Naratriptan
1541:Almotriptan
1149:(7): 1719.
735:per year.
680:amino acids
672:proteolysis
623:sumatriptan
581:in adults.
521: g·mol
344:Identifiers
325:Proteolysis
135:MedlinePlus
108:Other names
99:Trade names
2592:Categories
2488:Bimagrumab
2405:Ozanezumab
2385:Crenezumab
2364:Opicinumab
2359:Fulranumab
2327:Aducanumab
2307:Neurologic
2263:Emicizumab
2258:Demcizumab
2152:Nesvacumab
2147:Inclacumab
2137:Evolocumab
2132:Evinacumab
2127:Enoticumab
2112:Alirocumab
2107:Abelacimab
2078:Stamulumab
2044:Blosozumab
1916:Rimegepant
1847:Topiramate
1819:Imipramine
1728:Lomerizine
1723:Dotarizine
1671:Zavegepant
1666:Ubrogepant
1661:Rimegepant
1624:Dotarizine
1599:Lasmiditan
1551:Eletriptan
1546:Avitriptan
1486:Ergotamine
1350:4 November
779:References
742:, but the
696:Amgen Inc.
536:medication
510:Molar mass
415:I5I8VB78VT
390:ChemSpider
350:CAS Number
320:Metabolism
269:Schedule D
2549:Phase III
2537:Withdrawn
2502:Humanized
2452:Humanized
2430:Tanezumab
2410:Ponezumab
2373:Humanized
2354:Fasinumab
2342:Lecanemab
2332:Donanemab
2273:Faricimab
2221:Humanized
2206:Abciximab
2188:Imciromab
2183:Biciromab
2167:Rinucumab
2157:Orticumab
2142:Icrucumab
2037:Humanized
2028:Denosumab
2023:Burosumab
1951:Phase III
1939:Withdrawn
1911:Atogepant
1852:Valproate
1791:Clonidine
1733:Verapamil
1639:Pizotifen
1634:Oxetorone
1594:Alniditan
1490:+caffeine
1468:Ergolines
1055:7 October
1030:7 October
797:Drugs.com
733:US$ 6,900
727:Economics
707:phase III
674:to small
650:(CGRPR).
629:enzymes.
597:, muscle
334:half-life
205:Routes of
179:Pregnancy
127:Monograph
121:Drugs.com
2582:Medicine
2349:Erenumab
2198:Chimeric
1883:Erenumab
1692:Amidrine
1533:Triptans
1524:agonists
1500:Lisuride
1385:Archived
1368:(2016).
1341:Archived
1308:Archived
1276:Archived
1246:Archived
1213:Archived
1181:Archived
1165:30550780
1116:Archived
1087:Archived
1050:ClinCalc
1025:ClinCalc
999:Archived
994:Medscape
972:29171821
916:Archived
872:Archived
868:DailyMed
833:Archived
801:Archived
771:and the
700:Novartis
676:peptides
595:pruritus
579:migraine
559:Novartis
544:migraine
528:Erenumab
370:DrugBank
219:ATC code
194: B1
181:category
168:Erenumab
163:DailyMed
34:Erenumab
1784:Timolol
716:placebo
709:STRIVE
705:In the
690:History
534:, is a
532:Aimovig
471:Formula
379:DB14039
339:28 days
265: /
261::
235:)
229: (
227:N02CD01
165::
141:a618029
103:Aimovig
18:Aimovig
2568:Portal
2532:WHO-EM
1934:WHO-EM
1867:CGRP-R
1680:Others
1612:Others
1586:Ditans
1163:
1005:21 May
970:
839:29 May
658:After
599:spasms
567:
446:ChEMBL
435:D10928
280:℞-only
278:
267:
263:℞-only
161:
82:Target
70:Source
2613:Amgen
2481:Human
2315:Human
2176:Mouse
2100:Human
2071:Human
2016:Human
1861:Anti-
1388:(PDF)
1383:(2).
1373:(PDF)
1344:(PDF)
1333:(PDF)
1096:2 May
1090:(PDF)
1079:(PDF)
922:4 May
912:(EMA)
807:5 May
763:Names
555:Amgen
87:CGRPR
75:Human
2008:Bone
1870:mAbs
1863:CGRP
1520:5-HT
1441:N02C
1396:2022
1352:2018
1316:2018
1284:2019
1272:NICE
1254:2019
1221:2019
1161:PMID
1143:Cell
1124:2022
1098:2019
1057:2022
1032:2022
1007:2018
968:PMID
924:2020
880:2022
841:2022
809:2020
678:and
557:and
497:2018
491:1728
485:9964
479:6472
426:KEGG
406:UNII
397:none
304:data
117:AHFS
60:Type
1151:doi
1147:175
958:doi
954:377
519:.98
517:871
515:145
232:WHO
2594::
2545::
1947::
1492:,
1381:30
1379:.
1375:.
1335:.
1300:.
1274:.
1270:.
1244:.
1238:.
1211:.
1205:.
1187:,
1159:.
1145:.
1141:.
1081:.
1065:^
1048:.
1023:.
991:.
980:^
966:.
952:.
948:.
932:^
914:.
907:.
888:^
866:.
849:^
825:.
795:.
775:.
702:.
617:,
605:.
593:,
550:.
503:50
286:EU
274:US
258:CA
190:AU
158:US
2570::
2236:/
1991:e
1984:t
1977:v
1865:/
1522:1
1496:)
1488:(
1443:)
1429:e
1422:t
1415:v
1398:.
1354:.
1318:.
1286:.
1256:.
1223:.
1167:.
1153::
1100:.
1059:.
1034:.
1009:.
974:.
960::
926:.
882:.
843:.
811:.
500:S
494:O
488:N
482:H
476:C
288::
276::
192::
119:/
20:)
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
