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Alcohol dependence

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that define a state of addiction. ... A large body of literature has demonstrated that such ΔFosB induction in D1-type neurons increases an animal's sensitivity to drug as well as natural rewards and promotes drug self-administration, presumably through a process of positive reinforcement ... Another ΔFosB target is cFos: as ΔFosB accumulates with repeated drug exposure it represses c-Fos and contributes to the molecular switch whereby ΔFosB is selectively induced in the chronic drug-treated state.. ... Moreover, there is increasing evidence that, despite a range of genetic risks for addiction across the population, exposure to sufficiently high doses of a drug for long periods of time can transform someone who has relatively lower genetic loading into an addict.
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or could benefit from medication treatment with psychosocial treatment, while others could just benefit from psychosocial treatment. Listed below are some different types of treatments that are used with treating alcohol dependency/alcohol use disorder depending on several factors that vary from person to person.
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A 2015 study found that alcohol dependency may have genetic risk factors. Linkage disequilibrium between an AD-associated GABA receptor gene cluster, GABRB3/GABRG3, and eye color genes, OCA2/HERC2, as well as between AD-associated GRM5 and pigmentation-associated TYR, were all associated with alcohol
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Withdrawals from alcohol dependence is a common side effect that occurs when a person with the dependency stops drinking abruptly or even cuts back on their drinking after a prolonged period of indulgence. Withdrawal from alcohol dependence can vary from mild, moderate to severe, depending on several
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Because only 3 of the 7 DSM-IV criteria for alcohol dependence are required, not all patients meet the same criteria and therefore not all have the same symptoms and problems related to drinking. Not everyone with alcohol dependence, therefore, experiences physiological dependence. Alcohol dependence
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Addiction: A term used to indicate the most severe, chronic stage of substance-use disorder, in which there is a substantial loss of self-control, as indicated by compulsive drug taking despite the desire to stop taking the drug. In the DSM-5, the term addiction is synonymous with the classification
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Substance-use disorder: A diagnostic term in the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) referring to recurrent use of alcohol or other drugs that causes clinically and functionally significant impairment, such as health problems, disability, and failure to
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The alcohol dependence syndrome was seen as a cluster of seven elements that concur. It was argued that not all elements may be present in every case, but the picture is sufficiently regular and coherent to permit clinical recognition. The syndrome was also considered to exist in degrees of severity
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Acceptance and mindfulness-based interventions show evidence of efficacy in being used to target Alcohol Use Disorder. These types of interventions are often most effectively delivered in group settings, however, they are also proven effective in individual therapy contexts. Overall, this is crucial
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and/or recovery. There are several reasons why someone with alcohol use disorder or alcohol dependency would seek treatment. This can either be a personal reason or because of law enforcement. There is a series of different levels of treatment processes depending on the severity subtype. Some would
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Despite the importance of numerous psychosocial factors, at its core, drug addiction involves a biological process: the ability of repeated exposure to a drug of abuse to induce changes in a vulnerable brain that drive the compulsive seeking and taking of drugs, and loss of control over drug use,
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The contemporary definition of alcohol dependence is still based upon early research. There has been considerable scientific effort over the past several decades to identify and understand the core features of alcohol dependence. This work began in 1976, when the British psychiatrist Griffith
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In alcohol dependence, reduction of alcohol, as defined within DSM-IV, can be attained by learning to control the use of alcohol. That is, a client can be offered a social learning approach that helps them to 'cope' with external pressures by re-learning their pattern of drinking alcohol. In
672:, a healthier lifestyle (physically and mentally), creating new relationships with other like-minded people as well as rekindling or mending old relationships if possible. The treatment process consists typically of two parts short-term and long-term. First, there is the path to 425:(AUDIT) is considered the most accurate alcohol screening tool for identifying potential alcohol misuse, including dependence. It was developed by the World Health Organization, designed initially for use in primary healthcare settings with supporting guidance. 624:
Treatments for alcohol dependence can be separated into two groups, those directed towards severely alcohol-dependent people, and those focused for those at risk of becoming dependent on alcohol. Treatment for alcohol dependence often involves utilizing
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The term 'alcohol dependence' has replaced 'alcoholism' as a term in order that individuals do not internalize the idea of cure and disease, but can approach alcohol as a chemical they may depend upon to cope with outside pressures.
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in helping individuals who are dependent on alcohol because it raises awareness, provides a non-judgemental environment for people to express their thoughts, and allows individuals to be heard and accepted in the present moment.
360:. However, many definitions of alcoholism exist, and only some are compatible with alcohol abuse. There are two major differences between alcohol dependence and alcoholism as generally accepted by the medical community. 364:
Alcohol dependence refers to an entity in which only alcohol is the involved addictive agent. Alcoholism refers to an entity in which alcohol or any cross-tolerant addictive agent is involved.
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rather than as a categorical absolute. Thus, the proper question is not 'whether a person is dependent on alcohol', but 'how far along the path of dependence has a person progressed'.
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dependency. GABA downregulation may decrease sensitivity to the toxic effects of alcohol, leading to increased alcohol consumption in blue-eyed individuals.
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Edwards and his American colleague Milton M. Gross collaborated to produce a formulation of what had previously been understood as 'alcoholism' – the
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meet major responsibilities at work, school, or home. Depending on the level of severity, this disorder is classified as mild, moderate, or severe.
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Hasin D; et al. (2007). "Prevalence, Correlates, Disability, and Comorbidity of DSM-IV Alcohol Abuse and Dependence in the United States".
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AUDIT has replaced older screening tools such as CAGE but there are many shorter alcohol screening tools, mostly derived from the AUDIT. The
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Using coding therapy to treat alcohol and drug addiction. Manipulations in psychotherapy. Rostov-on-Don, Feniks, 251 p. 2004. 251 p.
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criteria for alcohol dependence, at least three out of seven of the following criteria must be manifest during a 12-month period:
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Malenka RC, Nestler EJ, Hyman SE (2009). "Chapter 15: Reinforcement and Addictive Disorders". In Sydor A, Brown RY (eds.).
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Withdrawals (depending on severity of symptoms, could be accompanied with supervision by medical personal and medication)
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Edwards G. & Gross MM, Alcohol dependence: provisional description of a clinical syndrome, BMJ 1976; i: 1O58-106
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About 12% of American adults have had an alcohol dependence problem at some time in their life. In the UK the
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alcoholism, patients are generally not presumed to be 'in remission' unless they are abstinent from alcohol.
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Clark, David, Background Briefing, Alcohol Dependence, Drink and Drug News, 7 February 2005, p. 11
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Sulovari, Arvis; Kranzler, Henry R.; Farrer, Lindsay A.; Gelernter, Joel; Li, Dawei (July 2015).
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is also a popular faith-based process used by those wishing to recover from alcohol dependence.
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Social, occupational and recreational pursuits are given up or reduced because of alcohol use
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The following elements are the template for which the degree of dependence is judged:
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Use is continued despite knowledge of alcohol-related harm (physical or psychological)
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estimates that around 9% of men and 4% of UK women show signs of alcohol dependence.
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Increased salience of the need for alcohol over competing needs and responsibilities.
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Irving B. Weiner; Donald K. Freedheim; George Stricker; Thomas A. Widiger (2003).
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The spectrum of alcohol withdrawal symptoms range from such minor symptoms as
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factors such as: how long the person has been drinking, whether they are a
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The ultimate goal when it comes to treating alcohol dependence or as the
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Bayard, Max; McIntyre, Jonah; Hill, Keith; Woodside, Jack (2004-03-15).
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American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
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from drinking. There are several other benefits that come along with
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Persistent desire or unsuccessful efforts to cut down on alcohol use
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Molecular Neuropharmacology: A Foundation for Clinical Neuroscience
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Relief or avoidance of withdrawal symptoms by further drinking.
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disorder characterized by persistent use of drugs (including
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and ICD-10) psychiatric diagnosis in which an individual is
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Time is spent obtaining alcohol or recovering from effects
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Use in larger amounts or for longer periods than intended
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Ban on caffeinated alcoholic drinks in the United States
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Arnold Little, MD Alcohol Dependence – extensive article
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to severe complications such as withdrawal seizures and
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Witkiewitz, K.; Litten, R.; Leggio, L. (2019-09-25).
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Alcohol-related traffic crashes in the United States
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Community reinforcement approach and family training
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List of countries by alcohol consumption per capita
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MedicalBug. 6 January 2012. Archived from 454:Severity of Alcohol Dependence Questionnaire 411:Severity of Alcohol Dependence Questionnaire 391:Subjective awareness of compulsion to drink. 55:Women drinking during pregnancy can cause a 2228:Hallucinogen persisting perception disorder 1502:Handbook of Psychology: Clinical psychology 5013:Medicinal Liquor Prescriptions Act of 1933 4583:List of countries with alcohol prohibition 4463: 3737: 3714: 3700: 3692: 3631: 3525: 3485: 3385: 3328: 3314: 3306: 2979: 2860: 2601: 2572: 2558: 2550: 1823: 1816: 1678: 1664: 1656: 1555: 316:Withdrawal symptoms or clinically defined 273: 259: 29: 3915:Short-term effects of alcohol consumption 1474:(2). Missouri State Medical Association. 1170: 971: 918: 423:Alcohol Use Disorders Identification Test 903:"Cellular basis of memory for addiction" 828:Long-term effects of alcohol consumption 442:Online version of the CAGE questionnaire 108:, which combined alcohol dependence and 4553:Legal drinking age in the United States 2358:Kindling (sedative–hypnotic withdrawal) 846: 547:Hallucinations from alcohol withdrawal. 194:withdrawal symptoms (e.g., fatigue and 67:The effects of alcohol has on the body. 2501:Chronic solvent-induced encephalopathy 1505:. John Wiley and Sons. pp. 201–. 1030:"Alcohol use screening tests – GOV.UK" 694:Withdrawals (no medication aid needed) 119: 4536:List of dry communities by U.S. state 2025:Alcohol-induced respiratory reactions 376:Narrowing of the drinking repertoire. 7: 4049:List of methanol poisoning incidents 348:by the presence of symptoms such as 4770:Alcohol consumption recommendations 4695:Temperance and Good Citizenship Day 3243:Discrimination against drug addicts 1410:"Alcohol dependence and withdrawal" 4494:Alcohol packaging warning messages 4106:Alcohol use among college students 3768:Drunk driving in the United States 3105:Tobacco cessation clinics in India 2532:Anabolic-androgenic steroids abuse 2161:Synthetic cannabinoid use disorder 1462:Eissenberg, Joel C. (2024-03-14). 1234:"Alcohol Dependence and Treatment" 907:Dialogues in Clinical Neuroscience 25: 5053:Non-alcoholic fatty liver disease 5033:Index of alcohol-related articles 4476:Administrative License Suspension 2081:Caffeine-induced anxiety disorder 990:of severe substance-use disorder. 382:An acquired tolerance to alcohol. 123:Addiction and dependence glossary 5086: 5085: 4487:Alcoholic beverage control state 4283:Andrew Johnson alcoholism debate 3588:Hydromorphone (extended-release) 3290: 3289: 3168:Low-threshold treatment programs 3035:Motivational enhancement therapy 2134:Cannabinoid hyperemesis syndrome 719:Inpatient or outpatient programs 100:In 2013, it was reclassified as 4096:Alcohol in association football 3248:Dopamine dysregulation syndrome 3238:Category:Vaccines against drugs 2091:Caffeine-induced sleep disorder 1983:Fetal alcohol spectrum disorder 952:New England Journal of Medicine 750:"The Drunkard's Progress", 1846 656:, is to help with establishing 394:Reinstatement after abstinence. 339:Other alcohol-related disorders 57:fetal alcohol spectrum disorder 4308:List of deaths through alcohol 4126:Epidemiology of binge drinking 3930:Subjective response to alcohol 2485:Sudden sniffing death syndrome 2140:Intravenous marijuana syndrome 1734:Post-acute-withdrawal syndrome 1376:Archives of General Psychiatry 405:Alcohol abuse § Screening 292:Alcohol abuse § Diagnosis 1: 4793:Sweat alcohol content monitor 3828:Alcoholism in rural Australia 2871:Adverse childhood experiences 2312:Opioid-induced endocrinopathy 1196:"Alcohol Withdrawal Syndrome" 1151:Alcohol Research & Health 1121:www.markjayalcoholdetox.co.uk 709:assertive community treatment 4716:Adult Children of Alcoholics 4504:Drunk driving law by country 3920:Long-term effects of alcohol 3838:Disease theory of alcoholism 3823:Alcoholism in family systems 3813:Alcohol and Native Americans 3100:Nicotine replacement therapy 3085:Intensive outpatient program 3073:Residential treatment center 3013:Cognitive behavioral therapy 2525:Anabolic-androgenic steroids 2052:(alcohol use disorder (AUD)) 1994:Positional alcohol nystagmus 1959:Alcohol-related brain damage 901:Nestler EJ (December 2013). 485:side effects are as listed: 4443:International whisk(e)y day 3757:Driving under the influence 3593:Morphine (extended-release) 2698:Internet addiction disorder 2389:Benzodiazepine use disorder 2318:Opioid-induced constipation 2306:Opioid-induced hyperalgesia 2000:Wernicke–Korsakoff syndrome 1964:Alcohol withdrawal syndrome 1753:Substance-related disorders 1718:Substance-induced psychosis 1690:substance-related disorders 1081:"World Health Organization" 782:alcohol dependence syndrome 318:alcohol withdrawal syndrome 296:Alcoholism § Diagnosis 5138: 4959:Christian views on alcohol 4565:List of alcohol laws of US 3843:High-functioning alcoholic 3636:Tooltip Adrenergic agonist 3530:Tooltip Adrenergic agonist 3490:Tooltip Adrenergic agonist 3390:Tooltip Adrenergic agonist 3133:List of twelve-step groups 2086:Caffeine-induced psychosis 2017:Respiratory tract diseases 2002:(WKS, Korsakoff psychosis) 1799:Combined drug intoxication 1145:Becker, Howard C. (2008). 823:High-functioning alcoholic 402: 289: 93:(also chemically known as 5081: 4858:Alcoholic spirits measure 4843:Low-alcoholic malt drinks 4524:Ignition interlock device 4413:Drunken monkey hypothesis 4246:Routes of administration 3875:Alcohol congener analysis 3818:Alcoholism in adolescence 3622:Benzodiazepine dependence 3285: 3198:Supervised injection site 3128:Addiction recovery groups 3080:Heroin-assisted treatment 3040:Motivational interviewing 2395:Benzodiazepine dependence 2379:Benzodiazepine withdrawal 2189:Prenatal cocaine exposure 1852:Gastrointestinal diseases 1388:10.1001/archpsyc.64.7.830 1200:American Family Physician 1088:World Health Organization 254: 127: 2881:Psychological dependence 2715:Digital media addictions 1954:Alcoholic polyneuropathy 1918:Alcohol-related dementia 1836:Alcoholic cardiomyopathy 1789:Polysubstance dependence 1762:Psychological dependence 1542:Alcohol Recovery Program 808:Alcohol-related dementia 203:psychological dependence 5038:Alcohol and spaceflight 4780:Alcohol server training 4653:Managed alcohol program 4231:Binge drinking devices 3925:Pharmacology of ethanol 3183:Needle exchange program 3173:Managed alcohol program 3151:Category:Harm reduction 2374:Benzodiazepine overdose 2006:Wernicke encephalopathy 1860:Alcoholic liver disease 1828:Cardiovascular diseases 833:Paddington alcohol test 507:Elevated blood pressure 344:is differentiated from 301:DSM: Alcohol dependence 4643:Alcohol rehabilitation 4611:Alcohol detoxification 4514:Field sobriety testing 4399:Health effects of wine 4367:International Beer Day 4131:Holiday heart syndrome 3203:Tobacco harm reduction 3023:Contingency management 2990:Alcohol detoxification 2703:Internet sex addiction 2460:Amphetamine dependence 2421:Barbiturate dependence 2252:Green Tobacco Sickness 2150:Amotivational syndrome 2030:Alcoholic lung disease 1970:Alcoholic hallucinosis 1949:Alcoholic hallucinosis 1897:Alcoholic ketoacidosis 1841:Alcohol flush reaction 1709:Substance intoxication 1264:"Alcohol use disorder" 751: 701:Psychosocial treatment 685: 548: 237:substance use disorder 68: 60: 4895:Disulfiram-like drugs 4435:Ritual use of alcohol 4404:Wine and food pairing 4389:ApĂ©ritif and digestif 4040:Adulterated moonshine 3887:Blood alcohol content 3849:Seeing pink elephants 3265:Motivational salience 3193:Stimulant maintenance 3178:Moderation Management 3090:Methadone maintenance 2155:Cannabis use disorder 1878:Auto-brewery syndrome 964:10.1056/NEJMra1511480 813:CRAFFT Screening Test 749: 684:Treatment and support 683: 600:Little to no appetite 546: 481:factors. Some common 112:into this diagnosis. 66: 54: 5122:Substance dependence 4964:Alcohol in the Bible 4951:Religion and alcohol 4917:General anaesthetics 4710:Alcoholics Anonymous 4668:List of mixed drinks 4121:Alcohol intoxication 4036:Adulterated alcohol 3188:Responsible drug use 3045:Motivational therapy 2710:Video game addiction 2411:Barbiturate overdose 2184:Cocaine intoxication 1924:Alcohol intoxication 1766:Substance dependence 1441:10.1002/ajmg.b.32316 818:Disulfiram-like drug 798:Alcohol intoxication 715:Alcoholics Anonymous 689:Types of treatments: 654:alcohol use disorder 534:Issues with sleeping 515:Body aches / tremors 385:Withdrawal symptoms. 102:alcohol use disorder 5043:Gateway drug effect 4829:Low-alcohol drinks 4658:Non-alcoholic drink 4593:Temperance movement 4575:Alcohol prohibition 4298:Gilbert Paul Jordan 4288:Dionysian Mysteries 4072:on college campuses 4067:Alcohol advertising 3785:Public intoxication 3447:General anesthetics 3351:Nicotine dependence 3112:Twelve-step program 2995:Drug detoxification 2876:Physical dependence 2444:Stimulant psychosis 2329:Opioid use disorder 2273:Nicotine dependence 2263:Nicotine withdrawal 2106:Caffeine dependence 1866:Alcoholic hepatitis 1758:Physical dependence 1729:Neonatal withdrawal 1244:on 27 February 2013 707:, psychoeducation, 643:Twelve-Step Program 556:Hypertensive crisis 187:physical dependence 4875:Addiction medicine 4818:Get Your Sexy Back 4758:Alcohol limitation 4734:Sober living house 4700:Twelve-step groups 4633:Brief intervention 4626:Open-container law 4588:Neo-prohibitionism 4548:Legal drinking age 4354:Alcoholic beverage 4255:Alcohol inhalation 4170:Drinking in public 4148:Blackout Wednesday 4006:Beverage-specific 3723:Alcohol and health 3601:Opioid antagonists 3461:Opioid antagonists 3439:Hydrogen cyanamide 3406:Alcohol dependence 3270:Incentive salience 3258:Inhibitory control 3233:Category:Addiction 3223:Addiction medicine 3018:Relapse prevention 2955:Tanning dependence 2258:Nicotine poisoning 2200:Cocaine dependence 2129:Cannabis arteritis 1989:Korsakoff syndrome 1889:Endocrine diseases 1633:2016-08-11 at the 752: 686: 627:relapse prevention 597:Mental pandemonium 549: 435:CAGE questionnaire 167:drug sensitization 72:Alcohol dependence 69: 61: 33:Alcohol dependence 18:Alcohol dependency 5099: 5098: 5021: 5020: 4971:Islam and alcohol 4905:Calcium carbimide 4775:Alcohol education 4663:List of cocktails 4638:Designated driver 4616:Alcohol-free zone 4519:Hip flask defence 4453: 4452: 4394:Hangover remedies 4338:Whiskey Rebellion 4328:Six o'clock swill 4116:Austrian syndrome 4055:Surrogate alcohol 4045:Denatured alcohol 4017:Red wine headache 3689: 3688: 3568:Levacetylmethadol 3516:Opioid dependence 3434:Calcium carbimide 3303: 3302: 3253:Cognitive control 3211: 3210: 3095:Smoking cessation 3050:Physical exercise 2965: 2964: 2951:Non-drug stimuli 2850: 2849: 2694:Internet-related 2547: 2546: 2301:Opioid withdrawal 2064: 2063: 2038: 2037: 1618: 1617: 1512:978-0-471-39263-7 1468:Missouri Medicine 1097:on April 23, 2004 725:(case management) 305:According to the 283: 282: 172:reverse tolerance 49: 48: 27:Medical condition 16:(Redirected from 5129: 5112:Drinking culture 5089: 5088: 4888:Chlordiazepoxide 4838:Low-alcohol beer 4482:Alcohol monopoly 4464: 4384:Drinking culture 4377:Women in brewing 4260:Vodka eyeballing 4227:Passive drinking 3738: 3716: 3709: 3702: 3693: 3663:Chlordiazepoxide 3637: 3633: 3583:Dihydroetorphine 3531: 3527: 3491: 3487: 3417: 3391: 3387: 3330: 3323: 3316: 3307: 3293: 3292: 2980: 2861: 2786:G9a-like protein 2602: 2574: 2567: 2560: 2551: 2491:Toluene toxicity 1975:Delirium tremens 1871:Zieve's syndrome 1824: 1817: 1680: 1673: 1666: 1657: 1556: 1544: 1539: 1533: 1530: 1524: 1523: 1521: 1519: 1496: 1490: 1489: 1487: 1486: 1459: 1453: 1452: 1420: 1414: 1413: 1406: 1400: 1399: 1371: 1365: 1364: 1347:(6): 1443–1450. 1341:Science Advances 1332: 1326: 1325: 1323: 1322: 1316:www.uptodate.com 1308: 1302: 1301: 1299: 1297: 1282: 1276: 1275: 1273: 1271: 1260: 1254: 1253: 1251: 1249: 1230: 1224: 1223: 1206:(6): 1443–1450. 1191: 1185: 1184: 1174: 1142: 1136: 1135: 1133: 1132: 1123:. Archived from 1113: 1107: 1106: 1104: 1102: 1096: 1090:. Archived from 1085: 1077: 1071: 1070: 1068: 1066: 1061:on 17 March 2012 1051: 1045: 1044: 1042: 1040: 1026: 1020: 1017: 1011: 1010: 1005:. Archived from 999: 993: 992: 975: 943: 937: 936: 922: 898: 892: 891: 873: 867: 866: 864: 862: 851: 639:short-term goals 614:delirium tremens 275: 268: 261: 196:delirium tremens 120: 30: 21: 5137: 5136: 5132: 5131: 5130: 5128: 5127: 5126: 5102: 5101: 5100: 5095: 5077: 5058:Self-medication 5017: 4975: 4945: 4883:Benzodiazepines 4869: 4753: 4739:Sobering center 4724:Sober companion 4705:Al-Anon/Alateen 4597: 4569: 4459: 4449: 4342: 4271: 4211:In vino veritas 4205:Hair of the dog 4023: 3939:Adverse effects 3934: 3903: 3853: 3799: 3743: 3742:Alcohol-related 3733: 3725: 3720: 3690: 3685: 3648:Benzodiazepines 3635: 3616: 3529: 3510: 3489: 3400: 3389: 3345: 3338:drug dependence 3334: 3304: 3299: 3281: 3277:Sober companion 3207: 3161:Reagent testing 3137: 3116: 3060: 3054: 3005: 2999: 2974: 2972: 2961: 2890: 2846: 2733:Transcriptional 2725: 2719: 2646: 2632:Methylphenidate 2627:Methamphetamine 2591: 2578: 2548: 2543: 2512: 2473: 2466: 2427: 2345: 2336: 2296:Opioid overdose 2279: 2235: 2206: 2167: 2112: 2060: 2034: 2011: 1940: 1933: 1910:system diseases 1909: 1902: 1883: 1846: 1806: 1778: 1772: 1749:Substance abuse 1692: 1684: 1635:Wayback Machine 1619: 1614: 1613: 1567: 1553: 1548: 1547: 1540: 1536: 1531: 1527: 1517: 1515: 1513: 1498: 1497: 1493: 1484: 1482: 1461: 1460: 1456: 1422: 1421: 1417: 1408: 1407: 1403: 1373: 1372: 1368: 1334: 1333: 1329: 1320: 1318: 1310: 1309: 1305: 1295: 1293: 1284: 1283: 1279: 1269: 1267: 1262: 1261: 1257: 1247: 1245: 1232: 1231: 1227: 1193: 1192: 1188: 1144: 1143: 1139: 1130: 1128: 1115: 1114: 1110: 1100: 1098: 1094: 1083: 1079: 1078: 1074: 1064: 1062: 1053: 1052: 1048: 1038: 1036: 1028: 1027: 1023: 1018: 1014: 1001: 1000: 996: 988: 945: 944: 940: 900: 899: 895: 888: 875: 874: 870: 860: 858: 857:. November 2013 853: 852: 848: 843: 803:Alcoholic drink 794: 773: 764: 762:Genetic factors 744: 729:Al-Anon/Alateen 723:Social services 622: 541: 504:Rapid heartbeat 491: 462: 450: 431: 419: 407: 401: 341: 303: 298: 288: 279: 179:drug withdrawal 137:biopsychosocial 118: 84:psychologically 74:is a previous ( 28: 23: 22: 15: 12: 11: 5: 5135: 5133: 5125: 5124: 5119: 5114: 5104: 5103: 5097: 5096: 5094: 5093: 5082: 5079: 5078: 5076: 5075: 5073:French paradox 5070: 5065: 5060: 5055: 5050: 5045: 5040: 5035: 5029: 5027: 5023: 5022: 5019: 5018: 5016: 5015: 5010: 5005: 5000: 4995: 4983: 4981: 4977: 4976: 4974: 4973: 4968: 4967: 4966: 4955: 4953: 4947: 4946: 4944: 4943: 4942: 4941: 4936: 4929:Sulfonic acids 4926: 4925: 4924: 4914: 4913: 4912: 4907: 4902: 4892: 4891: 4890: 4879: 4877: 4871: 4870: 4868: 4867: 4866: 4865: 4863:Standard drink 4860: 4852: 4851: 4850: 4845: 4840: 4835: 4827: 4825:Liquor license 4822: 4821: 4820: 4812: 4807: 4802: 4797: 4796: 4795: 4790: 4782: 4777: 4772: 4767: 4761: 4759: 4755: 4754: 4752: 4751: 4746: 4741: 4736: 4731: 4726: 4721: 4720: 4719: 4713: 4707: 4697: 4692: 4690:Temperance bar 4687: 4682: 4681: 4680: 4675: 4670: 4665: 4655: 4650: 4645: 4640: 4635: 4630: 4629: 4628: 4623: 4613: 4607: 4605: 4599: 4598: 4596: 4595: 4590: 4585: 4579: 4577: 4571: 4570: 4568: 4567: 4562: 4561: 4560: 4555: 4545: 4540: 4539: 4538: 4528: 4527: 4526: 4521: 4516: 4511: 4501: 4496: 4491: 4490: 4489: 4479: 4472: 4470: 4461: 4455: 4454: 4451: 4450: 4448: 4447: 4446: 4445: 4437: 4432: 4431: 4430: 4420: 4415: 4410: 4409: 4408: 4407: 4406: 4396: 4391: 4381: 4380: 4379: 4374: 4369: 4364: 4356: 4350: 4348: 4344: 4343: 4341: 4340: 4335: 4330: 4325: 4320: 4315: 4310: 4305: 4300: 4295: 4290: 4285: 4279: 4277: 4273: 4272: 4270: 4269: 4264: 4263: 4262: 4257: 4252: 4244: 4243: 4242: 4237: 4229: 4224: 4219: 4214: 4207: 4202: 4197: 4192: 4187: 4182: 4177: 4172: 4167: 4166: 4165: 4160: 4150: 4145: 4140: 4139: 4138: 4133: 4128: 4123: 4118: 4111:Binge drinking 4108: 4103: 4101:Alcohol powder 4098: 4093: 4091:Alcohol myopia 4088: 4087: 4086: 4076: 4075: 4074: 4064: 4059: 4058: 4057: 4052: 4042: 4033: 4031: 4025: 4024: 4022: 4021: 4020: 4019: 4013: 4004: 3999: 3990: 3985: 3980: 3975: 3970: 3969: 3968: 3958: 3953: 3948: 3942: 3940: 3936: 3935: 3933: 3932: 3927: 3922: 3917: 3911: 3909: 3905: 3904: 3902: 3901: 3899:Wine chemistry 3896: 3891: 3890: 3889: 3879: 3878: 3877: 3867: 3865:Beer chemistry 3861: 3859: 3855: 3854: 3852: 3851: 3846: 3840: 3835: 3830: 3825: 3820: 3815: 3809: 3807: 3801: 3800: 3798: 3797: 3792: 3787: 3782: 3777: 3772: 3771: 3770: 3760: 3754: 3748: 3746: 3735: 3727: 3726: 3721: 3719: 3718: 3711: 3704: 3696: 3687: 3686: 3684: 3683: 3671: 3665: 3660: 3655: 3644: 3626: 3624: 3618: 3617: 3615: 3614: 3608: 3597: 3596: 3595: 3590: 3585: 3580: 3578:Dihydrocodeine 3575: 3570: 3565: 3548: 3543: 3537: 3520: 3518: 3512: 3511: 3509: 3508: 3503: 3498: 3481: 3476: 3475: 3474: 3469: 3457: 3456: 3455: 3443: 3442: 3441: 3436: 3431: 3426: 3410: 3408: 3402: 3401: 3399: 3398: 3381: 3376: 3371: 3366: 3361: 3355: 3353: 3347: 3346: 3335: 3333: 3332: 3325: 3318: 3310: 3301: 3300: 3298: 3297: 3286: 3283: 3282: 3280: 3279: 3274: 3273: 3272: 3262: 3261: 3260: 3250: 3245: 3240: 3235: 3230: 3225: 3219: 3217: 3213: 3212: 3209: 3208: 3206: 3205: 3200: 3195: 3190: 3185: 3180: 3175: 3170: 3165: 3164: 3163: 3153: 3147: 3145: 3143:Harm reduction 3139: 3138: 3136: 3135: 3130: 3124: 3122: 3121:Support groups 3118: 3117: 3115: 3114: 3109: 3108: 3107: 3102: 3092: 3087: 3082: 3077: 3076: 3075: 3064: 3062: 3056: 3055: 3053: 3052: 3047: 3042: 3037: 3032: 3027: 3026: 3025: 3020: 3009: 3007: 3001: 3000: 2998: 2997: 2992: 2986: 2984: 2983:Detoxification 2977: 2967: 2966: 2963: 2962: 2960: 2959: 2958: 2957: 2949: 2948: 2947: 2942: 2937: 2932: 2927: 2922: 2920:Benzodiazepine 2917: 2912: 2907: 2898: 2896: 2892: 2891: 2889: 2888: 2883: 2878: 2873: 2867: 2865: 2858: 2852: 2851: 2848: 2847: 2845: 2844: 2843: 2842: 2839: 2834: 2829: 2824: 2819: 2814: 2809: 2802: 2795: 2788: 2783: 2770: 2769: 2768: 2767: 2762: 2757: 2752: 2747: 2742: 2729: 2727: 2721: 2720: 2718: 2717: 2712: 2707: 2706: 2705: 2700: 2692: 2691: 2690: 2685: 2677: 2675:Palatable food 2672: 2671: 2670: 2665: 2656: 2654: 2648: 2647: 2645: 2644: 2639: 2634: 2629: 2624: 2619: 2614: 2608: 2606: 2599: 2593: 2592: 2579: 2577: 2576: 2569: 2562: 2554: 2545: 2544: 2542: 2541: 2536: 2535: 2534: 2520: 2518: 2514: 2513: 2511: 2510: 2509: 2508: 2506:Inhalant abuse 2503: 2495: 2494: 2493: 2488: 2478: 2476: 2468: 2467: 2465: 2464: 2463: 2462: 2448: 2447: 2446: 2437: 2435: 2429: 2428: 2426: 2425: 2424: 2423: 2415: 2414: 2413: 2399: 2398: 2397: 2392: 2383: 2382: 2381: 2376: 2366:benzodiazepine 2362: 2361: 2360: 2351: 2349: 2338: 2337: 2335: 2334: 2333: 2332: 2323: 2322: 2321: 2315: 2309: 2303: 2298: 2289: 2287: 2281: 2280: 2278: 2277: 2276: 2275: 2267: 2266: 2265: 2260: 2255: 2245: 2243: 2237: 2236: 2234: 2233: 2232: 2231: 2225: 2216: 2214: 2208: 2207: 2205: 2204: 2203: 2202: 2194: 2193: 2192: 2186: 2177: 2175: 2169: 2168: 2166: 2165: 2164: 2163: 2158: 2152: 2144: 2143: 2142: 2137: 2131: 2122: 2120: 2114: 2113: 2111: 2110: 2109: 2108: 2100: 2099: 2098: 2093: 2088: 2083: 2074: 2072: 2066: 2065: 2062: 2061: 2059: 2058: 2056:Binge drinking 2053: 2046: 2044: 2040: 2039: 2036: 2035: 2033: 2032: 2027: 2021: 2019: 2013: 2012: 2010: 2009: 2003: 1997: 1991: 1986: 1980: 1979: 1978: 1972: 1961: 1956: 1951: 1945: 1943: 1935: 1934: 1932: 1931: 1926: 1921: 1914: 1912: 1904: 1903: 1901: 1900: 1893: 1891: 1885: 1884: 1882: 1881: 1875: 1874: 1873: 1868: 1856: 1854: 1848: 1847: 1845: 1844: 1838: 1832: 1830: 1821: 1814: 1808: 1807: 1805: 1804: 1803: 1802: 1793: 1792: 1791: 1782: 1780: 1774: 1773: 1771: 1770: 1769: 1768: 1755: 1741: 1740: 1739: 1738: 1737: 1731: 1720: 1715: 1700: 1698: 1694: 1693: 1685: 1683: 1682: 1675: 1668: 1660: 1654: 1653: 1641:R.R.Garifullin 1638: 1625: 1616: 1615: 1612: 1611: 1600: 1585: 1568: 1563: 1562: 1560: 1559:Classification 1552: 1551:External links 1549: 1546: 1545: 1534: 1525: 1511: 1491: 1454: 1435:(5): 347–353. 1415: 1401: 1366: 1327: 1303: 1292:on 19 May 2012 1277: 1255: 1238:ICAP Blue Book 1225: 1186: 1157:(4): 348–361. 1137: 1108: 1072: 1046: 1021: 1012: 1009:on 2005-03-24. 994: 958:(4): 363–371. 938: 913:(4): 431–443. 893: 886: 868: 845: 844: 842: 839: 836: 835: 830: 825: 820: 815: 810: 805: 800: 793: 790: 772: 769: 763: 760: 743: 740: 735: 734: 731: 726: 720: 717: 712: 698: 695: 637:, and setting 631:support groups 621: 618: 602: 601: 598: 595: 589: 583: 578: 573: 571:Hallucinations 564: 558: 553: 540: 537: 536: 535: 532: 529: 516: 513: 508: 505: 502: 497: 490: 487: 461: 458: 449: 446: 445: 444: 430: 427: 418: 415: 400: 397: 396: 395: 392: 389: 386: 383: 380: 377: 370: 369: 365: 340: 337: 336: 335: 332: 329: 326: 323: 320: 314: 302: 299: 287: 284: 281: 280: 278: 277: 270: 263: 255: 252: 251: 250: 249: 241: 233: 225: 216: 207: 199: 183: 175: 163: 155: 153:reward systems 148:addictive drug 144: 125: 124: 117: 114: 47: 46: 41: 35: 34: 26: 24: 14: 13: 10: 9: 6: 4: 3: 2: 5134: 5123: 5120: 5118: 5117:Alcohol abuse 5115: 5113: 5110: 5109: 5107: 5092: 5084: 5083: 5080: 5074: 5071: 5069: 5066: 5064: 5061: 5059: 5056: 5054: 5051: 5049: 5048:Mood disorder 5046: 5044: 5041: 5039: 5036: 5034: 5031: 5030: 5028: 5024: 5014: 5011: 5009: 5006: 5004: 5001: 4999: 4996: 4994: 4993: 4989: 4985: 4984: 4982: 4978: 4972: 4969: 4965: 4962: 4961: 4960: 4957: 4956: 4954: 4952: 4948: 4940: 4937: 4935: 4932: 4931: 4930: 4927: 4923: 4922:Nitrous oxide 4920: 4919: 4918: 4915: 4911: 4908: 4906: 4903: 4901: 4898: 4897: 4896: 4893: 4889: 4886: 4885: 4884: 4881: 4880: 4878: 4876: 4872: 4864: 4861: 4859: 4856: 4855: 4853: 4849: 4846: 4844: 4841: 4839: 4836: 4834: 4833:Fermented tea 4831: 4830: 4828: 4826: 4823: 4819: 4816: 4815: 4813: 4811: 4808: 4806: 4803: 4801: 4798: 4794: 4791: 4789: 4786: 4785: 4783: 4781: 4778: 4776: 4773: 4771: 4768: 4766: 4763: 4762: 4760: 4756: 4750: 4747: 4745: 4742: 4740: 4737: 4735: 4732: 4730: 4729:Sober curious 4727: 4725: 4722: 4717: 4714: 4711: 4708: 4706: 4703: 4702: 4701: 4698: 4696: 4693: 4691: 4688: 4686: 4683: 4679: 4676: 4674: 4671: 4669: 4666: 4664: 4661: 4660: 4659: 4656: 4654: 4651: 4649: 4646: 4644: 4641: 4639: 4636: 4634: 4631: 4627: 4624: 4622: 4619: 4618: 4617: 4614: 4612: 4609: 4608: 4606: 4604: 4600: 4594: 4591: 4589: 4586: 4584: 4581: 4580: 4578: 4576: 4572: 4566: 4563: 4559: 4556: 4554: 4551: 4550: 4549: 4546: 4544: 4541: 4537: 4534: 4533: 4532: 4529: 4525: 4522: 4520: 4517: 4515: 4512: 4510: 4507: 4506: 4505: 4502: 4500: 4497: 4495: 4492: 4488: 4485: 4484: 4483: 4480: 4477: 4474: 4473: 4471: 4469: 4465: 4462: 4456: 4444: 4441: 4440: 4438: 4436: 4433: 4429: 4426: 4425: 4424: 4421: 4419: 4418:Ladies' night 4416: 4414: 4411: 4405: 4402: 4401: 4400: 4397: 4395: 4392: 4390: 4387: 4386: 4385: 4382: 4378: 4375: 4373: 4370: 4368: 4365: 4363: 4360: 4359: 4357: 4355: 4352: 4351: 4349: 4345: 4339: 4336: 4334: 4331: 4329: 4326: 4324: 4321: 4319: 4318:Rum Rebellion 4316: 4314: 4311: 4309: 4306: 4304: 4301: 4299: 4296: 4294: 4291: 4289: 4286: 4284: 4281: 4280: 4278: 4274: 4268: 4265: 4261: 4258: 4256: 4253: 4251: 4250:Alcohol enema 4248: 4247: 4245: 4241: 4238: 4236: 4233: 4232: 4230: 4228: 4225: 4223: 4220: 4218: 4215: 4213: 4212: 4208: 4206: 4203: 4201: 4200:Flaming drink 4198: 4196: 4195:Dutch courage 4193: 4191: 4188: 4186: 4183: 4181: 4180:Drunk walking 4178: 4176: 4175:Drunk dialing 4173: 4171: 4168: 4164: 4161: 4159: 4156: 4155: 4154: 4153:Drinking game 4151: 4149: 4146: 4144: 4141: 4137: 4134: 4132: 4129: 4127: 4124: 4122: 4119: 4117: 4114: 4113: 4112: 4109: 4107: 4104: 4102: 4099: 4097: 4094: 4092: 4089: 4085: 4082: 4081: 4080: 4077: 4073: 4070: 4069: 4068: 4065: 4063: 4062:Alcohol abuse 4060: 4056: 4053: 4050: 4046: 4043: 4041: 4038: 4037: 4035: 4034: 4032: 4030: 4029:Social issues 4026: 4018: 4014: 4012: 4008: 4007: 4005: 4003: 4000: 3998: 3994: 3991: 3989: 3986: 3984: 3981: 3979: 3976: 3974: 3971: 3967: 3966:breast cancer 3964: 3963: 3962: 3959: 3957: 3954: 3952: 3949: 3947: 3944: 3943: 3941: 3937: 3931: 3928: 3926: 3923: 3921: 3918: 3916: 3913: 3912: 3910: 3906: 3900: 3897: 3895: 3894:Fusel alcohol 3892: 3888: 3885: 3884: 3883: 3880: 3876: 3873: 3872: 3871: 3868: 3866: 3863: 3862: 3860: 3856: 3850: 3847: 3844: 3841: 3839: 3836: 3834: 3831: 3829: 3826: 3824: 3821: 3819: 3816: 3814: 3811: 3810: 3808: 3806: 3802: 3796: 3793: 3791: 3788: 3786: 3783: 3781: 3778: 3776: 3773: 3769: 3766: 3765: 3764: 3763:Drunk driving 3761: 3758: 3755: 3753: 3750: 3749: 3747: 3745: 3739: 3736: 3732: 3728: 3724: 3717: 3712: 3710: 3705: 3703: 3698: 3697: 3694: 3681: 3680:Phenobarbital 3677: 3676: 3672: 3669: 3666: 3664: 3661: 3659: 3656: 3654: 3650: 3649: 3645: 3642: 3638: 3634: 3628: 3627: 3625: 3623: 3619: 3612: 3609: 3607: 3603: 3602: 3598: 3594: 3591: 3589: 3586: 3584: 3581: 3579: 3576: 3574: 3571: 3569: 3566: 3563: 3559: 3558:Buprenorphine 3556: 3555: 3554: 3553: 3549: 3547: 3544: 3541: 3538: 3536: 3532: 3528: 3522: 3521: 3519: 3517: 3513: 3507: 3504: 3502: 3499: 3496: 3492: 3488: 3482: 3480: 3477: 3473: 3470: 3468: 3465: 3464: 3463: 3462: 3458: 3454: 3453:Nitrous oxide 3451: 3450: 3449: 3448: 3444: 3440: 3437: 3435: 3432: 3430: 3427: 3425: 3422: 3421: 3420: 3419: 3412: 3411: 3409: 3407: 3403: 3396: 3392: 3388: 3382: 3380: 3377: 3375: 3372: 3370: 3367: 3365: 3362: 3360: 3357: 3356: 3354: 3352: 3348: 3343: 3339: 3336:Treatment of 3331: 3326: 3324: 3319: 3317: 3312: 3311: 3308: 3296: 3288: 3287: 3284: 3278: 3275: 3271: 3268: 3267: 3266: 3263: 3259: 3256: 3255: 3254: 3251: 3249: 3246: 3244: 3241: 3239: 3236: 3234: 3231: 3229: 3226: 3224: 3221: 3220: 3218: 3214: 3204: 3201: 3199: 3196: 3194: 3191: 3189: 3186: 3184: 3181: 3179: 3176: 3174: 3171: 3169: 3166: 3162: 3159: 3158: 3157: 3156:Drug checking 3154: 3152: 3149: 3148: 3146: 3144: 3140: 3134: 3131: 3129: 3126: 3125: 3123: 3119: 3113: 3110: 3106: 3103: 3101: 3098: 3097: 3096: 3093: 3091: 3088: 3086: 3083: 3081: 3078: 3074: 3071: 3070: 3069: 3066: 3065: 3063: 3057: 3051: 3048: 3046: 3043: 3041: 3038: 3036: 3033: 3031: 3028: 3024: 3021: 3019: 3016: 3015: 3014: 3011: 3010: 3008: 3002: 2996: 2993: 2991: 2988: 2987: 2985: 2981: 2978: 2976: 2968: 2956: 2953: 2952: 2950: 2946: 2943: 2941: 2938: 2936: 2933: 2931: 2928: 2926: 2923: 2921: 2918: 2916: 2913: 2911: 2908: 2906: 2903: 2902: 2900: 2899: 2897: 2893: 2887: 2884: 2882: 2879: 2877: 2874: 2872: 2869: 2868: 2866: 2862: 2859: 2857: 2853: 2840: 2838: 2835: 2833: 2830: 2828: 2825: 2823: 2820: 2818: 2815: 2813: 2810: 2808: 2807: 2803: 2801: 2800: 2796: 2794: 2793: 2789: 2787: 2784: 2782: 2781: 2777: 2776: 2775: 2772: 2771: 2766: 2763: 2761: 2758: 2756: 2753: 2751: 2748: 2746: 2743: 2741: 2740: 2736: 2735: 2734: 2731: 2730: 2728: 2722: 2716: 2713: 2711: 2708: 2704: 2701: 2699: 2696: 2695: 2693: 2689: 2686: 2684: 2681: 2680: 2678: 2676: 2673: 2669: 2666: 2664: 2661: 2660: 2658: 2657: 2655: 2653: 2649: 2643: 2640: 2638: 2635: 2633: 2630: 2628: 2625: 2623: 2620: 2618: 2615: 2613: 2610: 2609: 2607: 2603: 2600: 2598: 2594: 2590: 2586: 2582: 2581:Reinforcement 2575: 2570: 2568: 2563: 2561: 2556: 2555: 2552: 2540: 2537: 2533: 2530: 2529: 2527: 2526: 2522: 2521: 2519: 2515: 2507: 2504: 2502: 2499: 2498: 2496: 2492: 2489: 2486: 2483: 2482: 2480: 2479: 2477: 2475: 2469: 2461: 2458: 2457: 2455: 2453: 2449: 2445: 2442: 2441: 2439: 2438: 2436: 2434: 2430: 2422: 2419: 2418: 2416: 2412: 2409: 2408: 2406: 2404: 2400: 2396: 2393: 2390: 2387: 2386: 2384: 2380: 2377: 2375: 2372: 2371: 2369: 2367: 2363: 2359: 2356: 2355: 2353: 2352: 2350: 2348: 2343: 2339: 2330: 2327: 2326: 2324: 2319: 2316: 2313: 2310: 2307: 2304: 2302: 2299: 2297: 2294: 2293: 2291: 2290: 2288: 2286: 2282: 2274: 2271: 2270: 2268: 2264: 2261: 2259: 2256: 2253: 2250: 2249: 2247: 2246: 2244: 2242: 2238: 2229: 2226: 2224: 2221: 2220: 2218: 2217: 2215: 2213: 2209: 2201: 2198: 2197: 2195: 2190: 2187: 2185: 2182: 2181: 2179: 2178: 2176: 2174: 2170: 2162: 2159: 2156: 2153: 2151: 2148: 2147: 2145: 2141: 2138: 2135: 2132: 2130: 2127: 2126: 2124: 2123: 2121: 2119: 2115: 2107: 2104: 2103: 2101: 2097: 2094: 2092: 2089: 2087: 2084: 2082: 2079: 2078: 2076: 2075: 2073: 2071: 2067: 2057: 2054: 2051: 2048: 2047: 2045: 2041: 2031: 2028: 2026: 2023: 2022: 2020: 2018: 2014: 2007: 2004: 2001: 1998: 1995: 1992: 1990: 1987: 1984: 1981: 1976: 1973: 1971: 1968: 1967: 1965: 1962: 1960: 1957: 1955: 1952: 1950: 1947: 1946: 1944: 1942: 1936: 1930: 1927: 1925: 1922: 1919: 1916: 1915: 1913: 1911: 1905: 1898: 1895: 1894: 1892: 1890: 1886: 1879: 1876: 1872: 1869: 1867: 1864: 1863: 1861: 1858: 1857: 1855: 1853: 1849: 1842: 1839: 1837: 1834: 1833: 1831: 1829: 1825: 1822: 1818: 1815: 1813: 1809: 1800: 1797: 1796: 1794: 1790: 1787: 1786: 1784: 1783: 1781: 1779:substance use 1775: 1767: 1763: 1759: 1756: 1754: 1750: 1747: 1746: 1745: 1742: 1735: 1732: 1730: 1727: 1726: 1724: 1721: 1719: 1716: 1714: 1713:Drug overdose 1710: 1707: 1706: 1705: 1702: 1701: 1699: 1695: 1691: 1688: 1681: 1676: 1674: 1669: 1667: 1662: 1661: 1658: 1652: 1651:5-222-04382-7 1648: 1645: 1642: 1639: 1636: 1632: 1629: 1626: 1624: 1621: 1620: 1610: 1606: 1605: 1601: 1599: 1595: 1594: 1590: 1586: 1583: 1579: 1578: 1574: 1570: 1569: 1566: 1561: 1557: 1550: 1543: 1538: 1535: 1529: 1526: 1514: 1508: 1504: 1503: 1495: 1492: 1481: 1477: 1473: 1469: 1465: 1458: 1455: 1450: 1446: 1442: 1438: 1434: 1430: 1426: 1419: 1416: 1411: 1405: 1402: 1397: 1393: 1389: 1385: 1382:(7): 830–42. 1381: 1377: 1370: 1367: 1362: 1358: 1354: 1350: 1346: 1342: 1338: 1331: 1328: 1317: 1313: 1307: 1304: 1291: 1287: 1281: 1278: 1266:. Mayo Clinic 1265: 1259: 1256: 1243: 1239: 1235: 1229: 1226: 1221: 1217: 1213: 1209: 1205: 1201: 1197: 1190: 1187: 1182: 1178: 1173: 1168: 1164: 1160: 1156: 1152: 1148: 1141: 1138: 1127:on 2017-07-07 1126: 1122: 1118: 1112: 1109: 1093: 1089: 1082: 1076: 1073: 1060: 1056: 1050: 1047: 1035: 1031: 1025: 1022: 1016: 1013: 1008: 1004: 998: 995: 991: 983: 979: 974: 969: 965: 961: 957: 953: 949: 942: 939: 935: 930: 926: 921: 916: 912: 908: 904: 897: 894: 889: 887:9780071481274 883: 879: 872: 869: 856: 850: 847: 840: 838: 834: 831: 829: 826: 824: 821: 819: 816: 814: 811: 809: 806: 804: 801: 799: 796: 795: 791: 789: 785: 783: 777: 770: 768: 761: 759: 757: 748: 741: 739: 732: 730: 727: 724: 721: 718: 716: 713: 710: 706: 703:(counseling, 702: 699: 696: 693: 692: 691: 690: 682: 678: 675: 671: 667: 663: 659: 655: 652:now calls it 651: 646: 644: 640: 636: 635:psychotherapy 632: 628: 619: 617: 615: 611: 610:tremulousness 607: 599: 596: 594: 593:mood lability 590: 587: 584: 582: 579: 577: 574: 572: 568: 565: 562: 559: 557: 554: 551: 550: 545: 538: 533: 530: 528: 524: 520: 517: 514: 512: 509: 506: 503: 501: 498: 496: 493: 492: 488: 486: 484: 480: 476: 475:environmental 472: 471:psychological 468: 467:binge drinker 459: 457: 455: 447: 443: 440: 439: 438: 436: 428: 426: 424: 416: 414: 412: 406: 398: 393: 390: 387: 384: 381: 378: 375: 374: 373: 366: 363: 362: 361: 359: 355: 351: 347: 346:alcohol abuse 338: 333: 330: 327: 324: 321: 319: 315: 312: 311: 310: 308: 300: 297: 293: 285: 276: 271: 269: 264: 262: 257: 256: 253: 247: 246: 242: 239: 238: 234: 231: 230: 229:sensitization 226: 223: 221: 217: 214: 212: 208: 205: 204: 200: 197: 193: 189: 188: 184: 181: 180: 176: 173: 169: 168: 164: 161: 160: 156: 154: 150: 149: 145: 142: 138: 134: 133: 129: 128: 126: 121: 115: 113: 111: 110:alcohol abuse 107: 103: 98: 96: 92: 88: 85: 81: 77: 73: 65: 58: 53: 45: 42: 40: 36: 31: 19: 5008:Gin Act 1751 4998:Bratt System 4991: 4987: 4854:Measurement 4788:Breathalyzer 4558:Shoulder tap 4210: 4084:Beer goggles 3675:Barbiturates 3673: 3646: 3629: 3599: 3550: 3523: 3483: 3459: 3445: 3413: 3405: 3383: 3374:Mecamylamine 2804: 2797: 2790: 2778: 2737: 2679:Sex-related 2523: 2450: 2401: 2364: 2212:Hallucinogen 1939:Neurological 1687:Psychoactive 1602: 1587: 1571: 1537: 1528: 1516:. Retrieved 1501: 1494: 1483:. Retrieved 1471: 1467: 1457: 1432: 1428: 1418: 1404: 1379: 1375: 1369: 1344: 1340: 1330: 1319:. Retrieved 1315: 1306: 1294:. Retrieved 1290:the original 1280: 1268:. Retrieved 1258: 1246:. Retrieved 1242:the original 1237: 1228: 1203: 1199: 1189: 1154: 1150: 1140: 1129:. Retrieved 1125:the original 1120: 1111: 1099:. Retrieved 1092:the original 1087: 1075: 1063:. Retrieved 1059:the original 1049: 1037:. Retrieved 1033: 1024: 1015: 1007:the original 997: 985: 955: 951: 941: 932: 910: 906: 896: 877: 871: 859:. Retrieved 849: 837: 786: 781: 778: 774: 765: 753: 742:Epidemiology 736: 688: 687: 647: 623: 603: 523:Irritability 463: 451: 432: 420: 408: 371: 342: 304: 243: 235: 227: 218: 209: 201: 185: 177: 171: 165: 157: 146: 130: 99: 71: 70: 4988:Beer Street 4939:Homotaurine 4934:Acamprosate 4805:Dry January 4784:Monitoring 4685:Teetotalism 4678:Malt drinks 4468:Alcohol law 4240:Yard of ale 4185:Drunkorexia 3997:intolerance 3790:Rum-running 3429:Acamprosate 3379:Varenicline 3004:Behavioral 2915:Barbiturate 2910:Amphetamine 2688:Pornography 2683:Intercourse 2617:Amphetamine 2583:disorders: 2452:amphetamine 2403:barbiturate 666:self-esteem 576:Dehydration 531:Fuzzy brain 211:reinforcing 5106:Categories 5068:Town drunk 4900:Disulfiram 4848:Small beer 4814:Campaigns 4648:Drunk tank 4621:Dry campus 4531:Dry county 4313:Rum ration 4293:Dipsomania 4222:Pantsdrunk 4015:Red wine: 3805:Alcoholism 3795:Wine fraud 3606:Naltrexone 3540:Lofexidine 3479:Topiramate 3467:Naltrexone 3424:Disulfiram 3228:Allen Carr 3068:Drug rehab 3059:Treatment 2975:management 2971:Treatment 2905:Alcoholism 2886:Withdrawal 2856:Dependence 2774:Epigenetic 2726:mechanisms 2659:Financial 2652:Behavioral 2589:dependence 2433:Stimulants 2096:Caffeinism 2050:Alcoholism 1723:Withdrawal 1485:2024-05-21 1321:2021-05-18 1312:"UpToDate" 1131:2017-09-26 1034:www.gov.uk 674:abstinence 670:confidence 658:abstinence 527:Depression 483:withdrawal 479:biological 460:Withdrawal 403:See also: 358:alcoholism 354:withdrawal 290:See also: 159:dependence 116:Definition 80:physically 44:Psychiatry 5003:Dry state 4910:Cyanamide 4744:Sobrietol 4543:Last call 4509:DWI court 4362:Beer mile 4333:Speakeasy 4303:Gin Craze 4235:Beer bong 4190:Dry drunk 4163:Pregaming 4011:Potomania 3993:Tolerance 3983:Pregnancy 3858:Chemistry 3780:Nip joint 3775:Moonshine 3658:Lorazepam 3641:Clonidine 3611:Nalmefene 3573:Methadone 3562:+naloxone 3535:Clonidine 3495:Clonidine 3472:Nalmefene 3418:inhibitor 3395:Clonidine 3359:Bupropion 3006:therapies 2895:Disorders 2597:Addiction 2585:addiction 2539:Chocolate 1941:disorders 1449:1552-4841 1353:0002-838X 1270:4 October 1212:0002-838X 1163:1535-7414 662:treatment 620:Treatment 567:Delusions 563:/ Tremors 399:Screening 350:tolerance 313:Tolerance 286:Diagnosis 245:tolerance 220:rewarding 132:addiction 87:dependent 39:Specialty 5091:Category 4992:Gin Lane 4749:Quit lit 4673:Spritzer 4603:Sobriety 4458:Alcohol 4439:Whiskey 4267:Sconcing 4217:Nightcap 4143:Blackout 3973:Cortisol 3870:Congener 3668:Oxazepam 3653:Diazepam 3546:Ibogaine 3506:Phenibut 3501:Baclofen 3369:Lobeline 3364:Cytisine 3295:Category 3216:See also 3061:programs 2940:Nicotine 2930:Cannabis 2925:Caffeine 2864:Concepts 2724:Cellular 2668:Shopping 2663:Gambling 2637:Nicotine 2472:Volatile 2347:hypnotic 2342:Sedative 2241:Nicotine 2118:Cannabis 2070:Caffeine 1929:Hangover 1777:Combined 1631:Archived 1518:16 April 1480:27311215 1396:17606817 1361:15053409 1220:15053409 1181:23584009 982:26816013 929:24459410 792:See also 606:insomnia 591:Extreme 588:/ Shakes 561:Seizures 552:Vomiting 500:Vomiting 5026:Related 4980:History 4765:0-0-1-3 4460:control 4347:General 4323:Shebeen 4276:History 3946:Anxiety 3908:Effects 3882:Ethanol 3731:Alcohol 3552:Opioids 2935:Cocaine 2622:Cocaine 2612:Alcohol 2517:Related 2474:solvent 2285:Opioids 2173:Cocaine 1966:(AWS): 1908:Nervous 1862:(ALD): 1812:Alcohol 1697:General 1172:3860472 1101:8 April 1039:8 April 973:6135257 920:3898681 771:History 519:Anxiety 511:Fatigue 222:stimuli 213:stimuli 192:somatic 141:alcohol 95:ethanol 91:alcohol 4800:FRAMES 4009:Beer: 4002:Weight 3978:Memory 3961:Cancer 3744:crimes 2945:Opioid 2901:Drugs 2827:HDAC10 2642:Opioid 2528:: SUD 2487:(SSDS) 2230:(HPPD) 1985:(FASD) 1736:(PAWS) 1649:  1609:103780 1509:  1478:  1447:  1394:  1359:  1351:  1296:2 June 1248:2 June 1218:  1210:  1179:  1169:  1161:  1065:3 June 980:  970:  927:  917:  884:  641:. The 586:Chills 539:Severe 495:Nausea 477:, and 307:DSM-IV 294:, and 76:DSM-IV 5063:Spins 4718:(ACA) 4712:(AA): 4478:(ALS) 4358:Beer 4136:Zapoy 3988:Sleep 3956:Brain 3951:Aging 3845:(HFA) 3759:(DUI) 2837:SIRT2 2832:SIRT1 2822:HDAC9 2817:HDAC5 2812:HDAC4 2806:HDAC3 2799:HDAC2 2792:HDAC1 2765:NF-ÎşB 2760:GluR2 2745:c-Fos 2739:ΔFosB 2391:(BUD) 2331:(OUD) 2320:(OIC) 2314:(OIE) 2308:(OIH) 2254:(GTS) 2191:(PCE) 2157:(CUD) 2136:(CHS) 1996:(PAN) 1977:(DTs) 1920:(ARD) 1899:(AKA) 1880:(ABS) 1843:(AFR) 1801:(CDI) 1095:(PDF) 1084:(PDF) 861:9 May 841:Notes 650:DSM-5 581:Fever 417:AUDIT 106:DSM-5 89:upon 4990:and 4158:list 3342:N07B 2973:and 2755:CREB 2750:Cdk5 2605:Drug 2587:and 2497:SUD 2481:SID 2456:SUD 2440:SID 2417:SUD 2407:SID 2385:SUD 2370:SID 2354:SID 2325:SUD 2292:SID 2269:SUD 2248:SID 2219:SID 2196:SUD 2180:SID 2146:SUD 2125:SID 2102:SUD 2077:SID 2008:(WE) 1795:SID 1785:SUD 1647:ISBN 1604:OMIM 1593:9-CM 1520:2010 1507:ISBN 1476:PMID 1445:ISSN 1392:PMID 1357:PMID 1349:ISSN 1298:2012 1272:2020 1250:2012 1216:PMID 1208:ISSN 1177:PMID 1159:ISSN 1103:2018 1067:2012 1041:2018 978:PMID 925:PMID 882:ISBN 863:2015 668:and 608:and 489:Mild 452:The 448:SADQ 433:The 429:CAGE 421:The 352:and 135:– a 4079:Sex 3734:use 2841:... 2780:G9a 2043:SUD 1820:SID 1744:SUD 1704:SID 1598:303 1589:ICD 1582:F10 1573:ICD 1472:113 1437:doi 1433:168 1384:doi 1167:PMC 968:PMC 960:doi 956:374 915:PMC 756:NHS 705:CBT 170:or 104:in 97:). 82:or 5108:: 3632:AA 3526:AA 3486:AA 3416:AD 3386:AA 1764:/ 1760:/ 1751:/ 1725:: 1711:/ 1607:: 1596:: 1584:.2 1580:: 1577:10 1470:. 1466:. 1443:. 1431:. 1427:. 1390:. 1380:64 1378:. 1355:. 1345:69 1343:. 1339:. 1314:. 1236:. 1214:. 1204:69 1202:. 1198:. 1175:. 1165:. 1155:31 1153:. 1149:. 1119:. 1086:. 1032:. 984:. 976:. 966:. 954:. 950:. 931:. 923:. 911:15 909:. 905:. 784:. 633:, 629:, 569:/ 525:/ 521:/ 473:, 4051:) 4047:( 3995:/ 3715:e 3708:t 3701:v 3682:) 3678:( 3670:) 3651:( 3643:) 3639:( 3613:) 3604:( 3564:) 3560:( 3542:) 3533:( 3497:) 3493:( 3397:) 3393:( 3344:) 3340:( 3329:e 3322:t 3315:v 2573:e 2566:t 2559:v 2454:: 2405:: 2368:: 2344:/ 1679:e 1672:t 1665:v 1591:- 1575:- 1565:D 1522:. 1488:. 1451:. 1439:: 1412:. 1398:. 1386:: 1363:. 1324:. 1300:. 1274:. 1252:. 1222:. 1183:. 1134:. 1105:. 1069:. 1043:. 962:: 890:. 865:. 711:) 274:e 267:t 260:v 198:) 59:. 20:)

Index

Alcohol dependency
Specialty
Psychiatry

fetal alcohol spectrum disorder

DSM-IV
physically
psychologically
dependent
alcohol
ethanol
alcohol use disorder
DSM-5
alcohol abuse
addiction
biopsychosocial
alcohol
addictive drug
reward systems
dependence
drug sensitization
drug withdrawal
physical dependence
somatic
delirium tremens
psychological dependence
reinforcing
rewarding
sensitization

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