312:
289:
186:
211:
2042:
2027:
2057:
563:
318:
217:
2568:
31:
57:
2097:
1213:
Ouahchi K, Arita M, Kayden H, Hentati F, Ben Hamida M, Sokol R, Arai H, Inoue K, Mandel JL, Koenig M (1995). "Ataxia with isolated vitamin E deficiency is caused by mutations in the alpha-tocopherol transfer protein".
1844:
Klein RL, Semler AJ, Baynes JW, et al. (2005). "Glycation does not alter LDL-induced secretion of tissue plasminogen activator and plasminogen activator inhibitor-1 from human aortic endothelial cells".
1691:
MΓΌller-Schmehl K, Beninde J, Finckh B, et al. (2004). "Localization of alpha-tocopherol transfer protein in trophoblast, fetal capillaries' endothelium and amnion epithelium of human term placenta".
2090:
1729:
Mariotti C, Gellera C, Rimoldi M, et al. (2004). "Ataxia with isolated vitamin E deficiency: neurological phenotype, clinical follow-up and novel mutations in TTPA gene in
Italian families".
2083:
2041:
2026:
1360:
Ben Hamida C, Doerflinger N, Belal S, et al. (1994). "Localization of
Friedreich ataxia phenotype with selective vitamin E deficiency to chromosome 8q by homozygosity mapping".
2056:
325:
224:
1477:
Schuelke M, Mayatepek E, Inter M, et al. (1999). "Treatment of ataxia in isolated vitamin E deficiency caused by alpha-tocopherol transfer protein deficiency".
1588:
Meier R, Tomizaki T, Schulze-Briese C, et al. (2003). "The molecular basis of vitamin E retention: structure of human alpha-tocopherol transfer protein".
1397:
Hentati A, Deng HX, Hung WY, et al. (1996). "Human alpha-tocopherol transfer protein: gene structure and mutations in familial vitamin E deficiency".
821:
147:
802:
1919:
Attia J, Thakkinstian A, Wang Y, et al. (2007). "The PAI-1 4G/5G gene polymorphism and ischemic stroke: an association study and meta-analysis".
2187:
1506:
Cellini E, Piacentini S, Nacmias B, et al. (2003). "A family with spinocerebellar ataxia type 8 expansion and vitamin E deficiency ataxia".
2637:
1768:"The t-PA -7351C>T enhancer polymorphism decreases Sp1 and Sp3 protein binding affinity and transcriptional responsiveness to retinoic acid"
1115:
2613:
2006:
1195:
1177:
2632:
2478:
2359:
311:
1966:
1619:"Crystal structure of human alpha-tocopherol transfer protein bound to its ligand: implications for ataxia with vitamin E deficiency"
1029:
1036:
288:
1306:
1890:
Qian J, Atkinson J, Manor D (2006). "Biochemical consequences of heritable mutations in the alpha-tocopherol transfer protein".
1436:"Ataxia with isolated vitamin E deficiency: heterogeneity of mutations and phenotypic variability in a large number of families"
2346:
1164:
1143:
1160:
210:
185:
54:
1972:
1139:
127:
2281:
2224:
1327:"Adult-onset spinocerebellar dysfunction caused by a mutation in the gene for the alpha-tocopherol-transfer protein"
324:
223:
1662:
Morley S, Panagabko C, Shineman D, et al. (2004). "Molecular determinants of heritable vitamin E deficiency".
2606:
1999:
317:
216:
2336:
2258:
866:
135:
1960:
1803:"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)"
2417:
2341:
2137:
2114:
1307:"Entrez Gene: TTPA tocopherol (alpha) transfer protein (ataxia (Friedreich-like) with vitamin E deficiency)"
847:
1955:
2483:
2599:
2473:
1992:
1854:
1548:
199:
114:
118:, ATTP, AVED, TTP1, alphaTTP, tocopherol (alpha) transfer protein, alpha tocopherol transfer protein
2461:
2309:
2075:
1978:
1008:
961:
2050:: THE MOLECULAR BASIS OF VITAMIN E RETENTION: STRUCTURE OF HUMAN ALPHA-TOCOPHEROL TRANSFER PROTEIN
2035:: THE MOLECULAR BASIS OF VITAMIN E RETENTION: STRUCTURE OF HUMAN ALPHA-TOCOPHEROL TRANSFER PROTEIN
1878:
1754:
1717:
1422:
1385:
1239:
159:
1537:"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences"
1259:"Human alpha-tocopherol transfer protein: cDNA cloning, expression and chromosomal localization"
1012:
987:
957:
936:
1932:
2440:
2268:
1936:
1907:
1870:
1832:
1789:
1746:
1709:
1679:
1650:
1605:
1576:
1523:
1494:
1465:
1414:
1377:
1348:
1288:
1231:
107:
47:
2583:
2296:
1928:
1899:
1862:
1822:
1814:
1779:
1738:
1701:
1671:
1640:
1630:
1597:
1566:
1556:
1515:
1486:
1455:
1447:
1406:
1369:
1338:
1278:
1270:
1223:
404:
335:
279:
234:
562:
379:
155:
1858:
1552:
1460:
1435:
1283:
1258:
1827:
1802:
1645:
1618:
1601:
1571:
1536:
1490:
736:
731:
726:
721:
716:
711:
706:
701:
696:
691:
686:
681:
676:
660:
655:
650:
634:
629:
624:
619:
614:
609:
604:
2626:
2520:
1257:
Arita M, Sato Y, Miyata A, Tanabe T, Takahashi E, Kayden HJ, Arai H, Inoue K (1995).
591:
1882:
1758:
1721:
1426:
1389:
1243:
139:
2579:
397:
176:
2065:: Crystal Structure of Human Alpha-Tocopherol Transfer Protein Bound to its Ligand
1705:
163:
2373:
2286:
1519:
1343:
1326:
1200:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1182:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1784:
1767:
480:
2501:
2427:
2319:
2106:
1742:
1090:
296:
193:
143:
2409:
2216:
2165:
2147:
2129:
1866:
1635:
766:
540:
418:
363:
350:
262:
249:
151:
1940:
1911:
1874:
1836:
1793:
1750:
1713:
1683:
1654:
1609:
1580:
1561:
1527:
1498:
1469:
1418:
1410:
1381:
1352:
1292:
1235:
1076:
1071:
2543:
2245:
1060:
911:
892:
2201:
2177:
2110:
1818:
1373:
1227:
1096:
878:
833:
1903:
1675:
1274:
84:
80:
76:
2399:
2394:
1044:
788:
2567:
1451:
2538:
2533:
2528:
2496:
1956:
GeneReviews/NCBI/NIH/UW entry on Ataxia with
Vitamin E Deficiency
751:
747:
2575:
2506:
2389:
2384:
1103:
131:
2079:
1988:
571:
30:
1984:
1535:
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
707:
negative regulation of establishment of blood-brain barrier
387:
2587:
1801:
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
1434:
Cavalier L, Ouahchi K, Kayden HJ, et al. (1998).
552:
2519:
2460:
2453:
2426:
2408:
2372:
2318:
2295:
2267:
2244:
2237:
2215:
2164:
2146:
2128:
2121:
1001:
980:
950:
929:
1156:
1154:
1152:
1135:
1133:
1131:
334:
233:
1961:OMIM entries on Ataxia with Vitamin E Deficiency
1325:Gotoda T, Arita M, Arai H, et al. (1995).
18:Protein-coding gene in the species Homo sapiens
1921:Journal of Stroke and Cerebrovascular Diseases
1161:GRCm38: Ensembl release 89: ENSMUSG00000073988
2607:
2091:
2000:
625:phosphatidylinositol-4,5-bisphosphate binding
615:phosphatidylinositol-3,4-bisphosphate binding
8:
1140:GRCh38: Ensembl release 89: ENSG00000137561
2614:
2600:
2466:
2457:
2329:
2241:
2125:
2098:
2084:
2076:
2007:
1993:
1985:
1933:10.1016/j.jstrokecerebrovasdis.2007.03.002
1617:Min KC, Kovall RA, Hendrickson WA (2004).
762:
587:
375:
274:
171:
65:
1826:
1783:
1644:
1634:
1570:
1560:
1459:
1342:
1282:
2022:
1127:
1116:Familial isolated vitamin E deficiency
20:
339:
300:
295:
238:
197:
192:
7:
2564:
2562:
1766:Wolf AT, Medcalf RL, Jern C (2005).
2479:6-pyruvoyltetrahydropterin synthase
2360:Methylenetetrahydrofolate reductase
2586:. You can help Knowledge (XXG) by
998:
977:
947:
926:
902:
883:
857:
838:
812:
793:
557:
475:
413:
392:
14:
2156:Alpha-tocopherol transfer protein
1099:that in humans is encoded by the
702:negative regulation of cell death
2566:
2178:Sterol 27-hydroxylase or CYP27A1
2055:
2040:
2025:
561:
503:lumbar subsegment of spinal cord
323:
316:
310:
287:
222:
215:
209:
184:
29:
2347:Serine hydroxymethyltransferase
2192:1-alpha-hydroxylase or CYP27B1
697:embryonic placenta development
572:More reference expression data
541:More reference expression data
1:
2638:Human chromosome 8 gene stubs
1602:10.1016/S0022-2836(03)00724-1
1491:10.1016/S0022-3476(99)70424-5
308:
207:
1706:10.1080/10715760310001659611
1623:Proc. Natl. Acad. Sci. U.S.A
1541:Proc. Natl. Acad. Sci. U.S.A
732:intermembrane lipid transfer
2633:Genes on human chromosome 8
2282:Indoleamine 2,3-dioxygenase
2225:Vitamin K epoxide reductase
1520:10.1001/archneur.59.12.1952
1344:10.1056/NEJM199511163332003
727:vitamin E metabolic process
722:response to toxic substance
2654:
2561:
1977:gene details page in the
1785:10.1182/blood-2003-12-4383
677:intracellular pH reduction
523:sexually immature organism
465:mucosa of transverse colon
2492:
2469:
2355:
2332:
2206:24-hydroxylase or CYP24A1
2020:
1743:10.1007/s10072-004-0246-z
1196:"Mouse PubMed Reference:"
1178:"Human PubMed Reference:"
1075:
1070:
1066:
1059:
1043:
1024:
1005:
984:
973:
954:
933:
922:
909:
905:
890:
886:
877:
864:
860:
845:
841:
832:
819:
815:
800:
796:
787:
772:
765:
761:
745:
590:
586:
569:
560:
551:
538:
487:
478:
425:
416:
386:
378:
374:
357:
344:
307:
286:
277:
273:
256:
243:
206:
183:
174:
170:
125:
122:
112:
105:
100:
73:
68:
51:
46:
41:
37:
28:
23:
2337:Dihydropteroate synthase
2259:Thiamine diphosphokinase
2418:L-gulonolactone oxidase
2342:Dihydrofolate reductase
2202:1,25-Dihydroxyvitamin D
2138:Retinol binding protein
1867:10.1196/annals.1333.044
1636:10.1073/pnas.2136684100
1037:Chr 4: 20.01 β 20.03 Mb
1030:Chr 8: 63.05 β 63.09 Mb
635:lipid transfer activity
2238:Water soluble vitamins
1562:10.1073/pnas.242603899
2484:Sepiapterin reductase
1411:10.1002/ana.410390305
737:developmental process
2474:GTP cyclohydrolase I
2454:Nonvitamin cofactors
2122:Fat soluble vitamins
1971:genome location and
1847:Ann. N. Y. Acad. Sci
687:placenta development
682:response to nutrient
302:Chromosome 4 (mouse)
200:Chromosome 8 (human)
69:List of PDB id codes
42:Available structures
2462:Tetrahydrobiopterin
2310:Pantothenate kinase
2188:25-Hydroxyvitamin D
1979:UCSC Genome Browser
1859:2005NYASA1043..379K
1553:2002PNAS...9916899M
499:submandibular gland
429:right lobe of liver
341:4 A3|4 7.76 cM
2574:This article on a
1819:10.1101/gr.2596504
1374:10.1038/ng1093-195
1228:10.1038/ng0295-141
867:ENSMUSG00000073988
670:Biological process
644:Cellular component
598:Molecular function
491:left lobe of liver
433:buccal mucosa cell
2595:
2594:
2556:
2555:
2552:
2551:
2515:
2514:
2449:
2448:
2441:Riboflavin kinase
2368:
2367:
2233:
2232:
2113:, coenzymes, and
2073:
2072:
1904:10.1021/bi060522c
1676:10.1021/bi0363073
1547:(26): 16899β903.
1440:Am. J. Hum. Genet
1275:10.1042/bj3060437
1086:
1085:
1082:
1081:
1055:
1054:
1020:
1019:
995:
994:
969:
968:
944:
943:
918:
917:
899:
898:
873:
872:
854:
853:
828:
827:
809:
808:
757:
756:
717:vitamin transport
610:vitamin E binding
582:
581:
578:
577:
547:
546:
534:
533:
472:
471:
453:nucleus accumbens
370:
369:
269:
268:
96:
95:
92:
91:
52:Ortholog search:
2645:
2616:
2609:
2602:
2570:
2563:
2467:
2458:
2330:
2297:Pantothenic acid
2242:
2126:
2100:
2093:
2086:
2077:
2059:
2044:
2029:
2009:
2002:
1995:
1986:
1944:
1915:
1886:
1840:
1830:
1797:
1787:
1762:
1725:
1687:
1658:
1648:
1638:
1613:
1584:
1574:
1564:
1531:
1502:
1473:
1463:
1430:
1393:
1356:
1346:
1311:
1310:
1303:
1297:
1296:
1286:
1254:
1248:
1247:
1210:
1204:
1203:
1192:
1186:
1185:
1174:
1168:
1158:
1147:
1137:
1093:transfer protein
1068:
1067:
1039:
1032:
1015:
999:
990:
978:
974:RefSeq (protein)
964:
948:
939:
927:
903:
884:
858:
839:
813:
794:
763:
692:lipid metabolism
588:
574:
565:
558:
543:
483:
481:Top expressed in
476:
449:ventricular zone
421:
419:Top expressed in
414:
393:
376:
366:
353:
342:
327:
320:
314:
303:
291:
275:
265:
252:
241:
226:
219:
213:
202:
188:
172:
166:
164:TTPA - orthologs
117:
110:
87:
66:
60:
39:
38:
33:
21:
2653:
2652:
2648:
2647:
2646:
2644:
2643:
2642:
2623:
2622:
2621:
2620:
2559:
2557:
2548:
2511:
2488:
2445:
2433:
2422:
2404:
2377:
2364:
2351:
2325:
2314:
2302:
2291:
2274:
2263:
2251:
2229:
2211:
2205:
2191:
2160:
2142:
2117:
2104:
2074:
2069:
2066:
2060:
2051:
2045:
2036:
2030:
2016:
2013:
1952:
1947:
1918:
1898:(27): 8236β42.
1889:
1843:
1813:(10B): 2121β7.
1800:
1765:
1728:
1694:Free Radic. Res
1690:
1661:
1629:(25): 14713β8.
1616:
1587:
1534:
1505:
1476:
1433:
1396:
1359:
1331:N. Engl. J. Med
1324:
1320:
1318:Further reading
1315:
1314:
1305:
1304:
1300:
1256:
1255:
1251:
1212:
1211:
1207:
1194:
1193:
1189:
1176:
1175:
1171:
1159:
1150:
1138:
1129:
1124:
1112:
1077:View/Edit Mouse
1072:View/Edit Human
1035:
1028:
1025:Location (UCSC)
1011:
1007:
986:
960:
956:
935:
848:ENSG00000137561
741:
665:
639:
620:protein binding
605:vitamin binding
570:
539:
530:
525:
521:
517:
515:proximal tubule
513:
509:
505:
501:
497:
493:
479:
468:
463:
459:
457:caudate nucleus
455:
451:
447:
443:
439:
435:
431:
417:
361:
348:
340:
330:
329:
328:
321:
301:
278:Gene location (
260:
247:
239:
229:
228:
227:
220:
198:
175:Gene location (
126:
113:
106:
75:
53:
19:
12:
11:
5:
2651:
2649:
2641:
2640:
2635:
2625:
2624:
2619:
2618:
2611:
2604:
2596:
2593:
2592:
2571:
2554:
2553:
2550:
2549:
2547:
2546:
2541:
2536:
2531:
2525:
2523:
2517:
2516:
2513:
2512:
2510:
2509:
2504:
2499:
2493:
2490:
2489:
2487:
2486:
2481:
2476:
2470:
2464:
2455:
2451:
2450:
2447:
2446:
2444:
2443:
2437:
2435:
2431:
2424:
2423:
2421:
2420:
2414:
2412:
2406:
2405:
2403:
2402:
2397:
2392:
2387:
2381:
2379:
2375:
2370:
2369:
2366:
2365:
2363:
2362:
2356:
2353:
2352:
2350:
2349:
2344:
2339:
2333:
2327:
2323:
2316:
2315:
2313:
2312:
2306:
2304:
2300:
2293:
2292:
2290:
2289:
2284:
2278:
2276:
2272:
2265:
2264:
2262:
2261:
2255:
2253:
2249:
2239:
2235:
2234:
2231:
2230:
2228:
2227:
2221:
2219:
2213:
2212:
2210:
2209:
2203:
2195:
2189:
2181:
2170:
2168:
2162:
2161:
2159:
2158:
2152:
2150:
2144:
2143:
2141:
2140:
2134:
2132:
2123:
2119:
2118:
2105:
2103:
2102:
2095:
2088:
2080:
2071:
2070:
2068:
2067:
2061:
2054:
2052:
2046:
2039:
2037:
2031:
2024:
2021:
2018:
2017:
2014:
2012:
2011:
2004:
1997:
1989:
1983:
1982:
1963:
1958:
1951:
1950:External links
1948:
1946:
1945:
1916:
1887:
1841:
1798:
1763:
1726:
1688:
1670:(14): 4143β9.
1659:
1614:
1585:
1532:
1514:(12): 1952β3.
1503:
1474:
1452:10.1086/301699
1431:
1405:(3): 295β300.
1394:
1368:(2): 195β200.
1357:
1337:(20): 1313β8.
1321:
1319:
1316:
1313:
1312:
1298:
1269:(2): 437β443.
1249:
1222:(2): 141β145.
1205:
1187:
1169:
1148:
1126:
1125:
1123:
1120:
1119:
1118:
1111:
1108:
1084:
1083:
1080:
1079:
1074:
1064:
1063:
1057:
1056:
1053:
1052:
1050:
1048:
1041:
1040:
1033:
1026:
1022:
1021:
1018:
1017:
1003:
1002:
996:
993:
992:
982:
981:
975:
971:
970:
967:
966:
952:
951:
945:
942:
941:
931:
930:
924:
920:
919:
916:
915:
907:
906:
900:
897:
896:
888:
887:
881:
875:
874:
871:
870:
862:
861:
855:
852:
851:
843:
842:
836:
830:
829:
826:
825:
817:
816:
810:
807:
806:
798:
797:
791:
785:
784:
779:
774:
770:
769:
759:
758:
755:
754:
743:
742:
740:
739:
734:
729:
724:
719:
714:
712:response to pH
709:
704:
699:
694:
689:
684:
679:
673:
671:
667:
666:
664:
663:
658:
653:
647:
645:
641:
640:
638:
637:
632:
627:
622:
617:
612:
607:
601:
599:
595:
594:
584:
583:
580:
579:
576:
575:
567:
566:
555:
549:
548:
545:
544:
536:
535:
532:
531:
529:
528:
524:
520:
516:
512:
508:
504:
500:
496:
492:
488:
485:
484:
473:
470:
469:
467:
466:
462:
458:
454:
450:
446:
442:
438:
434:
430:
426:
423:
422:
410:
409:
401:
390:
384:
383:
380:RNA expression
372:
371:
368:
367:
359:
355:
354:
346:
343:
338:
332:
331:
322:
315:
309:
305:
304:
299:
293:
292:
284:
283:
271:
270:
267:
266:
258:
254:
253:
245:
242:
237:
231:
230:
221:
214:
208:
204:
203:
196:
190:
189:
181:
180:
168:
167:
124:
120:
119:
111:
103:
102:
98:
97:
94:
93:
90:
89:
71:
70:
62:
61:
50:
44:
43:
35:
34:
26:
25:
17:
13:
10:
9:
6:
4:
3:
2:
2650:
2639:
2636:
2634:
2631:
2630:
2628:
2617:
2612:
2610:
2605:
2603:
2598:
2597:
2591:
2589:
2585:
2581:
2577:
2572:
2569:
2565:
2560:
2545:
2542:
2540:
2537:
2535:
2532:
2530:
2527:
2526:
2524:
2522:
2521:Molybdopterin
2518:
2508:
2505:
2503:
2500:
2498:
2495:
2494:
2491:
2485:
2482:
2480:
2477:
2475:
2472:
2471:
2468:
2465:
2463:
2459:
2456:
2452:
2442:
2439:
2438:
2436:
2429:
2425:
2419:
2416:
2415:
2413:
2411:
2407:
2401:
2398:
2396:
2393:
2391:
2388:
2386:
2383:
2382:
2380:
2378:
2371:
2361:
2358:
2357:
2354:
2348:
2345:
2343:
2340:
2338:
2335:
2334:
2331:
2328:
2321:
2317:
2311:
2308:
2307:
2305:
2298:
2294:
2288:
2285:
2283:
2280:
2279:
2277:
2270:
2266:
2260:
2257:
2256:
2254:
2247:
2243:
2240:
2236:
2226:
2223:
2222:
2220:
2218:
2214:
2207:
2199:
2196:
2193:
2185:
2182:
2179:
2175:
2172:
2171:
2169:
2167:
2163:
2157:
2154:
2153:
2151:
2149:
2145:
2139:
2136:
2135:
2133:
2131:
2127:
2124:
2120:
2116:
2112:
2108:
2101:
2096:
2094:
2089:
2087:
2082:
2081:
2078:
2064:
2058:
2053:
2049:
2043:
2038:
2034:
2028:
2023:
2019:
2010:
2005:
2003:
1998:
1996:
1991:
1990:
1987:
1980:
1976:
1975:
1970:
1969:
1964:
1962:
1959:
1957:
1954:
1953:
1949:
1942:
1938:
1934:
1930:
1926:
1922:
1917:
1913:
1909:
1905:
1901:
1897:
1893:
1888:
1884:
1880:
1876:
1872:
1868:
1864:
1860:
1856:
1853:(1): 379β89.
1852:
1848:
1842:
1838:
1834:
1829:
1824:
1820:
1816:
1812:
1808:
1804:
1799:
1795:
1791:
1786:
1781:
1778:(3): 1060β7.
1777:
1773:
1769:
1764:
1760:
1756:
1752:
1748:
1744:
1740:
1736:
1732:
1727:
1723:
1719:
1715:
1711:
1707:
1703:
1700:(4): 413β20.
1699:
1695:
1689:
1685:
1681:
1677:
1673:
1669:
1665:
1660:
1656:
1652:
1647:
1642:
1637:
1632:
1628:
1624:
1620:
1615:
1611:
1607:
1603:
1599:
1596:(3): 725β34.
1595:
1591:
1586:
1582:
1578:
1573:
1568:
1563:
1558:
1554:
1550:
1546:
1542:
1538:
1533:
1529:
1525:
1521:
1517:
1513:
1509:
1504:
1500:
1496:
1492:
1488:
1484:
1480:
1475:
1471:
1467:
1462:
1457:
1453:
1449:
1446:(2): 301β10.
1445:
1441:
1437:
1432:
1428:
1424:
1420:
1416:
1412:
1408:
1404:
1400:
1395:
1391:
1387:
1383:
1379:
1375:
1371:
1367:
1363:
1358:
1354:
1350:
1345:
1340:
1336:
1332:
1328:
1323:
1322:
1317:
1308:
1302:
1299:
1294:
1290:
1285:
1280:
1276:
1272:
1268:
1264:
1260:
1253:
1250:
1245:
1241:
1237:
1233:
1229:
1225:
1221:
1217:
1209:
1206:
1201:
1197:
1191:
1188:
1183:
1179:
1173:
1170:
1166:
1162:
1157:
1155:
1153:
1149:
1145:
1141:
1136:
1134:
1132:
1128:
1121:
1117:
1114:
1113:
1109:
1107:
1105:
1102:
1098:
1095:(Ξ±-TTP) is a
1094:
1092:
1078:
1073:
1069:
1065:
1062:
1058:
1051:
1049:
1046:
1042:
1038:
1034:
1031:
1027:
1023:
1016:
1014:
1010:
1004:
1000:
997:
991:
989:
983:
979:
976:
972:
965:
963:
959:
953:
949:
946:
940:
938:
932:
928:
925:
923:RefSeq (mRNA)
921:
914:
913:
908:
904:
901:
895:
894:
889:
885:
882:
880:
876:
869:
868:
863:
859:
856:
850:
849:
844:
840:
837:
835:
831:
824:
823:
818:
814:
811:
805:
804:
799:
795:
792:
790:
786:
783:
780:
778:
775:
771:
768:
764:
760:
753:
749:
744:
738:
735:
733:
730:
728:
725:
723:
720:
718:
715:
713:
710:
708:
705:
703:
700:
698:
695:
693:
690:
688:
685:
683:
680:
678:
675:
674:
672:
669:
668:
662:
659:
657:
656:late endosome
654:
652:
649:
648:
646:
643:
642:
636:
633:
631:
630:lipid binding
628:
626:
623:
621:
618:
616:
613:
611:
608:
606:
603:
602:
600:
597:
596:
593:
592:Gene ontology
589:
585:
573:
568:
564:
559:
556:
554:
550:
542:
537:
526:
522:
519:mammary gland
518:
514:
511:hair follicle
510:
506:
502:
498:
495:parotid gland
494:
490:
489:
486:
482:
477:
474:
464:
460:
456:
452:
448:
444:
440:
436:
432:
428:
427:
424:
420:
415:
412:
411:
408:
406:
402:
400:
399:
395:
394:
391:
389:
385:
381:
377:
373:
365:
360:
356:
352:
347:
337:
333:
326:
319:
313:
306:
298:
294:
290:
285:
281:
276:
272:
264:
259:
255:
251:
246:
236:
232:
225:
218:
212:
205:
201:
195:
191:
187:
182:
178:
173:
169:
165:
161:
157:
153:
149:
145:
141:
137:
133:
129:
121:
116:
109:
104:
99:
88:
86:
82:
78:
72:
67:
64:
63:
59:
56:
49:
45:
40:
36:
32:
27:
22:
16:
2588:expanding it
2580:chromosome 8
2573:
2558:
2197:
2183:
2173:
2155:
2062:
2047:
2032:
1973:
1967:
1927:(4): 173β9.
1924:
1920:
1895:
1892:Biochemistry
1891:
1850:
1846:
1810:
1806:
1775:
1771:
1737:(3): 130β7.
1734:
1730:
1697:
1693:
1667:
1664:Biochemistry
1663:
1626:
1622:
1593:
1590:J. Mol. Biol
1589:
1544:
1540:
1511:
1508:Arch. Neurol
1507:
1485:(2): 240β4.
1482:
1478:
1443:
1439:
1402:
1398:
1365:
1361:
1334:
1330:
1301:
1266:
1262:
1252:
1219:
1215:
1208:
1199:
1190:
1181:
1172:
1100:
1088:
1087:
1009:NP_001304652
1006:
985:
962:NM_001317723
955:
934:
910:
891:
865:
846:
820:
801:
781:
776:
527:human kidney
507:right kidney
403:
396:
123:External IDs
74:
15:
2287:Formamidase
2198:degradation
2015:PDB gallery
1731:Neurol. Sci
1399:Ann. Neurol
362:20,030,785
349:20,007,938
261:63,086,053
248:63,048,553
101:Identifiers
2627:Categories
2428:Riboflavin
2320:Folic acid
2107:Metabolism
1807:Genome Res
1479:J. Pediatr
1362:Nat. Genet
1167:, May 2017
1146:, May 2017
1122:References
1091:tocopherol
407:(ortholog)
144:HomoloGene
2578:on human
2410:Vitamin C
2374:Vitamin B
2217:Vitamin K
2166:Vitamin D
2148:Vitamin E
2130:Vitamin A
2115:cofactors
1263:Biochem J
1216:Nat Genet
1013:NP_056582
988:NP_000361
958:NM_015767
937:NM_000370
767:Orthologs
651:cytoplasm
152:GeneCards
2544:Gephyrin
2246:Thiamine
2111:vitamins
1941:17689414
1912:16819822
1883:21239765
1875:16037259
1837:15489334
1794:15466927
1759:25567441
1751:15300460
1722:85982835
1714:15190938
1684:15065857
1655:14657365
1610:12899840
1581:12477932
1528:12470185
1427:85193347
1390:33125913
1244:24917144
1163:–
1142:–
1110:See also
1061:Wikidata
746:Sources:
461:amygdala
445:testicle
1855:Bibcode
1549:Bibcode
1499:9931538
1470:9463307
1461:1376876
1419:8602747
1382:8252047
1353:7566022
1293:7887897
1284:1136538
1236:7719340
1165:Ensembl
1144:Ensembl
1097:protein
879:UniProt
834:Ensembl
773:Species
752:QuickGO
661:cytosol
382:pattern
140:1354168
108:Aliases
2400:MMADHC
2395:MMACHC
2269:Niacin
1965:Human
1939:
1910:
1881:
1873:
1835:
1828:528928
1825:
1792:
1757:
1749:
1720:
1712:
1682:
1653:
1646:299775
1643:
1608:
1579:
1572:139241
1569:
1526:
1497:
1468:
1458:
1425:
1417:
1388:
1380:
1351:
1291:
1281:
1242:
1234:
1089:Alpha-
1047:search
1045:PubMed
912:Q8BWP5
893:P49638
789:Entrez
553:BioGPS
441:rectum
240:8q12.3
132:600415
2582:is a
2539:MOCS3
2534:MOCS2
2529:MOCS1
2497:PCBD1
2184:renal
2174:liver
1879:S2CID
1772:Blood
1755:S2CID
1718:S2CID
1423:S2CID
1386:S2CID
1240:S2CID
822:50500
782:Mouse
777:Human
748:Amigo
437:gonad
405:Mouse
398:Human
345:Start
280:Mouse
244:Start
177:Human
148:37295
2584:stub
2576:gene
2507:QDPR
2390:MMAB
2385:MMAA
2063:1r5l
2048:1oiz
2033:1oip
1974:TTPA
1968:TTPA
1937:PMID
1908:PMID
1871:PMID
1851:1043
1833:PMID
1790:PMID
1747:PMID
1710:PMID
1680:PMID
1651:PMID
1606:PMID
1577:PMID
1524:PMID
1495:PMID
1466:PMID
1415:PMID
1378:PMID
1349:PMID
1289:PMID
1232:PMID
1104:gene
1101:TTPA
803:7274
388:Bgee
336:Band
297:Chr.
235:Band
194:Chr.
156:TTPA
128:OMIM
115:TTPA
85:1R5L
81:1OIZ
77:1OIP
58:RCSB
55:PDBe
24:TTPA
2502:PTS
2109:of
1929:doi
1900:doi
1863:doi
1823:PMC
1815:doi
1780:doi
1776:105
1739:doi
1702:doi
1672:doi
1641:PMC
1631:doi
1627:100
1598:doi
1594:331
1567:PMC
1557:doi
1516:doi
1487:doi
1483:134
1456:PMC
1448:doi
1407:doi
1370:doi
1339:doi
1335:333
1279:PMC
1271:doi
1267:306
1224:doi
358:End
257:End
160:OMA
136:MGI
48:PDB
2629::
2430:(B
2376:12
2322:(B
2299:(B
2271:(B
2248:(B
1935:.
1925:16
1923:.
1906:.
1896:45
1894:.
1877:.
1869:.
1861:.
1849:.
1831:.
1821:.
1811:14
1809:.
1805:.
1788:.
1774:.
1770:.
1753:.
1745:.
1735:25
1733:.
1716:.
1708:.
1698:38
1696:.
1678:.
1668:43
1666:.
1649:.
1639:.
1625:.
1621:.
1604:.
1592:.
1575:.
1565:.
1555:.
1545:99
1543:.
1539:.
1522:.
1512:59
1510:.
1493:.
1481:.
1464:.
1454:.
1444:62
1442:.
1438:.
1421:.
1413:.
1403:39
1401:.
1384:.
1376:.
1364:.
1347:.
1333:.
1329:.
1287:.
1277:.
1265:.
1261:.
1238:.
1230:.
1218:.
1198:.
1180:.
1151:^
1130:^
1106:.
750:/
364:bp
351:bp
263:bp
250:bp
158:;
154::
150:;
146::
142:;
138::
134:;
130::
83:,
79:,
2615:e
2608:t
2601:v
2590:.
2434:)
2432:2
2326:)
2324:9
2303:)
2301:5
2275:)
2273:3
2252:)
2250:1
2208:)
2204:3
2200:(
2194:)
2190:3
2186:(
2180:)
2176:(
2099:e
2092:t
2085:v
2008:e
2001:t
1994:v
1981:.
1943:.
1931::
1914:.
1902::
1885:.
1865::
1857::
1839:.
1817::
1796:.
1782::
1761:.
1741::
1724:.
1704::
1686:.
1674::
1657:.
1633::
1612:.
1600::
1583:.
1559::
1551::
1530:.
1518::
1501:.
1489::
1472:.
1450::
1429:.
1409::
1392:.
1372::
1366:5
1355:.
1341::
1309:.
1295:.
1273::
1246:.
1226::
1220:9
1202:.
1184:.
282:)
179:)
162::
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
