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Dutt is known to have made notable contributions in the field of cancer genetics, widening our understanding of the disease and its translational possibilities. The group led by him have been engaged in the study of the progression of cancer in the lung, breast, cervical, gallbladder, head and neck
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Amit Dutt, born on 6 September 1973 in Patna, capital of the Indian state of Bihar, earned a BSc in botany from
Desbandhu College, Delhi University in 1994 and continued there to complete a post-graduate diploma in Biochemical Technology in 1995 from the Sri Venkateswara College. Moving to
1180:
Dutt A, Salvesen HB, Chen TH, Ramos AH, Onofrio RC, Hatton C, Nicoletti R, Winckler W, Grewal R, Hanna M, Wyhs N, Ziaugra L, Richter DJ, Trovik J, Engelsen IB, Stefansson IM, Fennell T, Cibulskis K, Zody MC, Akslen LA, Gabriel S, Wong KK, Sellers WR, Meyerson M, Greulich H (2008).
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Apart from a number of student fellowships, Dutt has held research fellowships, starting with the Julius Klaus
Foundation Fellowship in 2004, followed by Swiss National Science Foundation Postdoctoral fellowship of the Government of Switzerland in 2005. The
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Chandrani P, Prabhash K, Prasad R, Sethunath V, Ranjan M, Iyer P, Aich J, Dhamne H, Iyer DN, Upadhyay P, Mohanty B, Chandna P, Kumar R, Joshi A, Noronha V, Patil V, Ramaswamy A, Karpe A, Thorat R, Chaudhari P, Ingle A, Choughule A, Dutt A (2016).
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Mittra I, Samant U, Sharma S, Raghuram GV, Saha T, Tidke P, Pancholi N, Gupta D, Prasannan P, Gaikwad A, Gardi N, Chaubal R, Upadhyay P, Pal K, Rane B, Shaikh A, Salunkhe S, Dutt S, Mishra PK, Khare NK, Nair NK, Dutt A (2017).
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which assists the doctors in deciding the surgical protocol in tongue cancer patients is another contribution of Dutt, which was the result of collaborative research with Sudhir Nair of TMC. They also identified a
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led to the
Epidermal Growth Factor Receptor (EGFR) and KRAS mutation profiling of Indian lung cancer patients for the first time. The research association between the duo has also led to the development of
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Upadhyay P, Nair S, Kaur E, Aich J, Dani P, Sethunath V, Gardi N, Chandrani P, Godbole M, Sonawane K, Prasad R, Kannan S, Agarwal B, Kane S, Gupta S, Dutt S, Dutt A (2016).
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Choughule A, Sharma R, Trivedi V, Thavamani A, Noronha V, Joshi A, Desai S, Chandrani P, Sundaram P, Utture S, Jambhekar N, Gupta S, Aich J, Prabhash K, Dutt A (2014).
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to secure a PhD in plant genetics in 2000, guided by Vanga Siva Reddy of Delhi
University and Arif Ali of Jamia Millia Islamia. Subsequently, he traveled to the
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Dutt continued in Zurich to work at the
Institute of Neuropathology of the university and in 2005, he moved to join the laboratory of Matthew Meyerson at the
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500:"Progesterone suppresses the invasion and migration of breast cancer cells irrespective of their progesterone receptor status - a short report"
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457:"Genomic characterization of tobacco/nut chewing HPV-negative early stage tongue tumors identify MMP10 asa candidate to predict metastases"
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where he is the principal investigator at scientist (grade F) and heads the
Integrated Cancer Genomics Lab, popularly known as Dutt Lab.
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Dutt A, Ramos AH, Hammerman PS, Mermel C, Cho J, Sharifnia T, Chande A, Tanaka KE, Stransky N, Greulich H, Gray NS, Meyerson M (2011).
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894:"Coexistence of KRAS mutation with mutant but not wild-type EGFR predicts response to tyrosine-kinase inhibitors in human lung cancer"
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588:"Cell-free chromatin from dying cancer cells integrate into genomes of bystander healthy cells toinduce DNA damage and inflammation"
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and working under the guidance of Alex Hajnal at the
Institute of Molecular Life Sciences of the university, secured another PhD in
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Noronha V, Prabhash K, Thavamani A, Chougule A, Purandare N, Joshi A, Sharma R, Desai S, Jambekar N, Dutt A, Mulherkar R (2013).
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Chougule A, Prabhash K, Noronha V, Joshi A, Thavamani A, Chandrani P, Upadhyay P, Utture S, Desai S, Jambhekar N, Dutt A (2013).
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signature which associated tobacco chewing with oral cancer. His studies have been documented by way of a number of articles and
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Chandrani P, Upadhyay P, Iyer P, Tanna M, Shetty M, Raghuram GV, Oak N, Singh A, Chaubal R, Ramteke M, Gupta S, Dutt A (2015).
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631:"MYOD1 (L122R) mutations are associated with spindle cell and sclerosing rhabdomyosarcomas with aggressive clinical outcomes"
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398:/ DBT India Alliance Intermediate Fellow in 2011. The Council of Scientific and Industrial Research awarded Dutt the
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Upadhyay P, Gardi N, Desai S, Sahoo B, Singh A, Togar T, Iyer P, Prasad R, Chandrani P, Gupta S, Dutt A (2016).
414:"miR-129-2 mediates down-regulation of progesterone receptor in response to progesterone in breast cancer cells"
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851:"NGS-based approach to determine the presence of HPV and their sites of integration in human cancer genome"
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1033:"EGFR mutations in Indian lung cancer patients: clinical correlation and outcome to EGFR targeted therapy"
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Upadhyay P, Gardi N, Desai S, Chandrani P, Joshi A, Dharavath B, Arora P, Bal M, Nair S, Dutt A (2017).
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and pathogen discovery. It is reported that the research collaboration Dutt had with Kumar
Prabhash of
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Chandrani P, Kulkarni V, Iyer P, Upadhyay P, Chaubal R, Das P, Mulherkar R, Singh R, Dutt A (2015).
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674:"Notch pathway activation is essential for maintenance of stem-like cells in early tongue cancer"
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Godbole M, Chandrani P, Gardi N, Dhamne H, Patel K, Yadav N, Gupta S, Badwe R, Dutt A (2017).
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806:"Integrated genomics approach to identify biologically relevant alterations in fewer samples"
219:(born 6 September 1973) is an Indian scientist, geneticist and the principal investigator at
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1139:"Somatic mutations are present in all members of the AKT family in endometrial carcinoma"
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Iyer P, Barreto SG, Sahoo B, Chandrani P, Ramadwar MR, Shrikhande SV, Dutt A (2016).
980:"Frequency of EGFR mutations in 907 lung adenocarcioma patients of Indian ethnicity"
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717:"TMC-SNPdb: an Indian germline variant database derived from whole exome sequences"
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1593:. Council of Scientific and Industrial Research. 17 October 2017. Archived from
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Dutt A, Salvesen HB, Greulich H, Sellers WR, Beroukhim R, Meyerson M (2009).
1086:"Inhibitor-sensitive FGFR1 amplification in human non-small cell lung cancer"
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937:"A genetic model for gallbladder carcinogenesis and its dissemination"
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Recipients of the Shanti Swarup
Bhatnagar Award in Medical Science
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as a research associate and worked there till 2010, stationing at
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Advanced Centre for Treatment, Research and Education in Cancer
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International Centre for Genetic Engineering and Biotechnology
761:"Non-typhoidal Salmonella DNA traces in gallbladder cancer"
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Dutt A, Canevascini S, Froehli-Hoier E, Hajnal A (2004).
1183:"Drug-sensitive FGFR2 mutations in endometrial carcinoma"
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affiliate. On his return to India in Oct 2010, he joined
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Shanti Swarup Bhatnagar Prize for Science and Technology
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Shanti Swarup Bhatnagar Prize for Science and Technology
544:"Drug-sensitive FGFR3 mutations in lung adenocarcinoma"
1507:"Amit Dutt, B.Sc, Ph.D., Ph.D. Principal Investigator"
498:
Godbole M, Tiwary K, Badwe R, Gupta S, Dutt A (2017).
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and his research may be classified under three heads;
1773:"10 scientists receive Shanti Swarup Bhatnagar Prize"
402:, one of the highest Indian science awards in 2017.
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2009:
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1588:"Handbook of Shanti Swarup Bhatnagar Prize Winners"
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Long link - please select award year to see details
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1385:. Shanti Swarup Bhatnagar Prize. 11 November 2017
1349:Curriculum vitae available in downloadable format
1568:. Shanti Swarup Bhatnagar Prize. 21 October 2017
629:Rekhi B, Upadhyay P, Ramteke MP, Dutt A (2016).
369:and holds memberships in associations such as
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241:Council of Scientific and Industrial Research
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2429:Academic staff of the University of Zurich
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1652:"Biomarker tells of tongue cancer spread"
1625:"It's a Moment of Pride for Jamia Millia"
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935:Barreto SG, Dutt A, Chaudhary A (2014).
371:American Association for Cancer Research
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1410:"Biographical Information - Amit Dutt"
345:, an experimental tool. Discovery of
7:
1807:Wellcome Trust - DBT India Alliance
473:10.1016/j.oraloncology.2017.08.003
285:Broad Institute of Harvard and MIT
239:Alliance Intermediate Fellow. The
14:
1679:. Google Scholar. 17 October 2017
1542:. 5 November 2017. Archived from
1452:. 5 November 2017. Archived from
1419:. 3 November 2017. Archived from
229:Fibroblast growth factor receptor
101:Fibroblast growth factor receptor
1536:"Integrated Cancer Genomics Lab"
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554:(3) (published 2017): 597–603.
365:Dutt is a member of faculty of
341:(both computational tools) and
121:DBT- Tata Innovation Fellowship
1803:"Amit Dutt - Research Summary"
1566:"Brief Profile of the Awardee"
1511:India Cancer Research Database
1:
1650:Prasad, R. (23 August 2017).
430:10.1080/15384047.2017.1373216
400:Shanti Swarup Bhatnagar Prize
115:Shanti Swarup Bhatnagar Prize
1253:10.1371/journal.pbio.0020334
1111:10.1371/journal.pone.0020351
1058:10.1371/journal.pone.0061561
1005:10.1371/journal.pone.0076164
289:Dana–Farber Cancer Institute
175:Dana–Farber Cancer Institute
2424:University of Zurich alumni
2419:Jamia Millia Islamia alumni
2231:Pundi Narasimhan Rangarajan
604:10.1038/cddiscovery.2017.15
392:Department of Biotechnology
227:. Known for his studies on
16:Indian academic (born 1973)
2450:
2314:Ganesan Venkatasubramanian
1953:Uttamchand Khimchand Sheth
647:10.1038/modpathol.2016.144
1446:"Dr. Amit Dutt-Biography"
1383:"View Bhatnagar Awardees"
823:10.1186/s12864-015-2138-4
778:10.1186/s13027-016-0057-x
690:10.18632/oncotarget.10419
516:10.1007/s13402-017-0330-z
210:
129:
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2394:Indian medical academics
1292:Matrix metalloproteinase
1187:Proc Natl Acad Sci U S A
2414:Delhi University alumni
2266:K. Narayanaswamy Balaji
1208:10.1073/pnas.0803379105
733:10.1093/database/baw104
1751:Ramalingaswami Fellows
1155:10.1038/sj.bjc.6605301
316:
315:Protein MMP10 PDB 1q3a
293:Harvard Medical School
260:
2409:Scientists from Bihar
2189:Birendra Nath Mallick
1830:"Amit Dutt on PubMed"
1721:"F1000 Prime faculty"
1360:Selected bibliography
953:10.1093/annonc/mdu006
560:10.1093/annonc/mdw636
406:Selected bibliography
314:
278:Developmental Biology
258:
200:Vanga Siva Reddy (DU)
2355:Jeemon Panniyammakal
1965:Ranjit Roy Chaudhury
910:10.1038/bjc.2014.401
867:10.1038/bjc.2015.121
765:Infect Agents Cancer
592:Cell Death Discovery
330:Tata Memorial Centre
297:Tata Memorial Centre
274:University of Zurich
266:Jamia Millia Islamia
225:Tata Memorial Centre
87:University of Zurich
77:Jamia Millia Islamia
2290:Vidita Ashok Vaidya
2219:Javed Naim Agrewala
2082:Maharaj Kishan Bhan
1941:M. J. Thirumalachar
1779:. 26 September 2017
1677:"On Google Scholar"
1481:"About Fellow-Dutt"
1199:2008PNAS..105.8713D
1102:2011PLoSO...620351D
1049:2013PLoSO...861561N
996:2013PLoSO...876164C
684:(31): 50437–50449.
326:functional genomics
2434:Indian geneticists
2326:Mohammad Javed Ali
2243:Santosh G. Honavar
1546:on 7 November 2017
1456:on 7 November 2017
1426:on 7 November 2017
504:Cell Oncol (Dordr)
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2207:Anil Kumar Mandal
2160:G. Balakrish Nair
1917:V. Ramalingaswami
1905:Bal Krishan Anand
1836:. 5 November 2017
1809:. 5 November 2017
1753:. 6 November 2017
1747:"List of Fellows"
1727:. 5 November 2017
1701:. 17 October 2017
1699:"On ResearchGate"
1513:. 5 November 2017
1487:. 5 November 2017
641:(12): 1532–1540.
385:Awards and honors
307:Legacy and honors
214:
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165:Zurich University
131:Scientific career
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2367:Dipyaman Ganguly
2361:Rohit Srivastava
2237:Ravinder Goswami
2047:B. S. Srivastava
2029:U. C. Chaturvedi
1923:J. B. Chatterjea
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259:Delhi University
197:Alex Hajnal (ZU)
190:Doctoral advisor
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2118:Y. D. Sharma
2112:K. B. Sainis
1988:O. M. Gulati
1982:J. R. Talwar
1838:. Retrieved
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1454:the original
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231:, Dutt is a
223:(ACTREC) of
216:
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153:Institutions
130:
18:
2399:1973 births
2308:Deepak Gaur
2296:Niyaz Ahmed
2272:Sandip Basu
2154:Vijay Kumar
2148:S. K. Gupta
2142:S. K. Sarin
2130:A. K. Tyagi
2124:S. K. Panda
2100:N. K. Mehra
2041:J. N. Sinha
2035:Indira Nath
2023:T. Desiraju
2017:P. R. Adiga
1994:A. K. Maiti
1911:N. K. Dutta
1899:R. B. Arora
1783:11 November
1725:F1000 Prime
1629:Okhla Times
1389:11 November
1358:Please see
1143:Br J Cancer
898:Br J Cancer
855:Br J Cancer
635:Mod. Pathol
367:F1000 Prime
349:protein, a
335:HPVDetector
301:Navi Mumbai
99:Studies on
2383:Categories
1935:A. K. Basu
1929:R.J. Vakil
1840:5 November
1813:5 November
1757:6 November
1731:5 November
1705:17 October
1683:17 October
1661:5 November
1635:5 November
1604:17 October
1572:21 October
1550:5 November
1517:5 November
1491:5 November
1460:5 November
1430:3 November
1369:References
941:Ann. Oncol
727:: baw104.
678:Oncotarget
548:Ann. Oncol
461:Oral Oncol
381:journals.
119:2023
113:2017
46:1973-09-06
2302:Amit Dutt
2201:C. S. Dey
2106:G. P. Pal
2094:U. N. Das
1777:The Hindu
1656:The Hindu
1240:PLOS Biol
598:: 17015.
467:: 56–64.
351:biomarker
339:TMC-SNPdb
280:in 2004.
251:Biography
237:DBT India
217:Amit Dutt
25:Amit Dutt
1280:See also
1272:15455032
1227:18552176
1173:19738612
1130:21666749
1090:PLOS ONE
1077:23620765
1037:PLOS ONE
1024:24124538
984:PLOS ONE
971:24705974
928:25117816
885:25973533
842:26572163
797:26941832
751:27402678
721:Database
708:27391340
665:27562493
622:28580170
578:27998968
534:28653288
491:28939077
448:28876975
379:PLoS One
2065:P. Seth
1362:section
1218:2438391
1195:Bibcode
1164:2768084
1121:3110189
1098:Bibcode
1068:3631198
1045:Bibcode
1015:3790706
992:Bibcode
962:4037856
919:4260019
876:4580395
833:4647579
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699:5226594
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613:5447133
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525:5537311
482:5628952
439:5678702
59:, India
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180:ACTREC
137:Fields
107:Awards
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2253:2010s
2176:2000s
2075:1990s
2010:1980s
1975:1970s
1892:1960s
1598:(PDF)
1591:(PDF)
1424:(PDF)
1413:(PDF)
1329:Notes
347:MMP10
160:ICGEB
82:ICGEB
57:Patna
1842:2017
1815:2017
1785:2017
1759:2017
1733:2017
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1391:2017
1268:PMID
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747:PMID
725:2016
704:PMID
661:PMID
618:PMID
574:PMID
530:PMID
487:PMID
444:PMID
377:and
337:and
291:, a
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Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
