429:. This protein is also trimeric and remains in the cytoplasm. It is covalently modified by a U/U deuridylylated group at Y51. The hydrolyzed product, adenosine 5'-diphosphate, orients the surface of GlnK for AmtB blockade. When nitrogen levels outside the cell rise, the ammonia channel must be deactivated to prevent excessive ammonia entering the cell (where ammonia would be combined with glutamate to make glutamine, utilizing
433:
and thereby depleting the cell's ATP reserves). This deactivation is achieved by deuridylylation of the GlnK protein which then binds to the cytoplasmic face of AmtB and inserts a loop into the ammonia conducting pore. At the tip of this loop is an
266:
subunits in which RhD and RhCE might play roles in anchoring the ammonia-conducting RhAG subunit to the cytoskeleton. Based on reconstitution experiments, purified RhCG subunits alone can function to transport ammonia. RhCG is required for normal
1556:
26:
298:
While prokaryotic ammonia channel proteins have an N-terminal region which acts as a signal sequence and is cleaved in the mature protein, the Rhesus glycoproteins retain this as a 12th transmembrane helix in the mature protein.
380:. This electronic density was initially only observed when crystals were grown in the presence of ammonium, and was thus attributed to ammonia molecules. The Amt/Rh protein mechanism might involve the single-file diffusion of NH
307:
Most functionally characterized members of the family are ammonium uptake transporters. Some, but not other Amt proteins also transport methylammonium. Detailed phylogenetic analyses of plant homologues have been published. In
845:
Biver S, Belge H, Bourgeois S, Van Vooren P, Nowik M, Scohy S, Houillier P, Szpirer J, Szpirer C, Wagner CA, Devuyst O, Marini AM (Nov 2008). "A role for Rhesus factor Rhcg in renal ammonium excretion and male fertility".
384:
molecules. However, the pore could also be filled with water molecules. The possible presence of water molecules in the pore lumen calls for a reassessment of the notion that Amt/Rh proteins work as plain
1560:
389:
channels. Indeed, functional experiments on plant ammonium transporters and Rh proteins suggest a variety of permeation mechanisms including the passive diffusion of NH
149:
588:
Khademi S, O'Connell J, Remis J, Robles-Colmenares Y, Miercke LJ, Stroud RM (Sep 2004). "Mechanism of ammonia transport by Amt/MEP/Rh: structure of AmtB at 1.35 A".
1588:
105:
93:
4609:
291:, was, at the time of its publication, the highest resolution structure of any integral membrane protein. It shows a trimer of subunits, each made up of 11
2968:
1307:
Ishikita, Hiroshi; Knapp, Ernst-Walter (2007-02-07). "Protonation states of ammonia/ammonium in the hydrophobic pore of ammonia transporter protein AmtB".
4009:
425:
the AmtB gene is expressed only under limiting nitrogen levels to yield the AmtB protein. It is co-expressed with the GlnK gene which encodes a
2874:
804:
4404:
3930:
1444:"In vitro analysis of the Escherichia coli AmtB-GlnK complex reveals a stoichiometric interaction and sensitivity to ATP and 2-oxoglutarate"
4262:
2130:
1799:
1566:
3272:
2766:
1692:
1687:
1612:
1581:
1399:
Lamoureux, G.; Javelle, A.; Baday, S.; Wang, S.; Bernèche, S. (2010-09-01). "Transport mechanisms in the ammonium transporter family".
254:
channel. The human RhCG ammonia transporter was found to have a similar ammonia-conducting channel structure. It was proposed that the
744:
Mouro-Chanteloup I, Cochet S, Chami M, Genetet S, Zidi-Yahiaoui N, Engel A, Colin Y, Bertrand O, Ripoche P (2010). Fatouros D (ed.).
485:
Gruswitz, F.; Chaudhary, S.; Ho, J. D.; Schlessinger, A.; Pezeshki, B.; Ho, C. -M.; Sali, A.; Westhoff, C. M.; Stroud, R. M. (2010).
4658:
4559:
3726:
2688:
1986:
1900:
1657:
2490:
426:
1242:"The W148L substitution in the Escherichia coli ammonium channel AmtB increases flux and indicates that the substrate is an ion"
2751:
1827:
1672:
372:
The X-ray structures have revealed that the pore of the Amt and Rh proteins is characterized by a hydrophobic portion about 12
4599:
2226:
4678:
4579:
4574:
4545:
3086:
2650:
2452:
2447:
1574:
987:
Soupene, Eric; King, Natalie; Feild, Eithne; Liu, Phillip; Niyogi, Krishna K.; Huang, Cheng-Han; Kustu, Sydney (2002-05-28).
536:
Nakhoul NL, Hamm LL (Feb 2004). "Non-erythroid Rh glycoproteins: a putative new family of mammalian ammonium transporters".
169:
2645:
2640:
2635:
2620:
2615:
2610:
2605:
2395:
3971:
3773:
3573:
709:
Khademi S, Stroud RM (Dec 2006). "The Amt/MEP/Rh family: structure of AmtB and the mechanism of ammonia gas conduction".
4569:
948:"The ammonia channel protein AmtB from Escherichia coli is a polytopic membrane protein with a cleavable signal peptide"
2561:
3541:
3420:
3124:
3493:
1996:
1605:
189:
4150:
3806:
2299:
295:(TMSs) and containing a pseudo two-fold symmetry. Each monomer contains a hydrophobic ammonia conducting channel.
4554:
2442:
4338:
1491:"The crystal structure of the Escherichia coli AmtB-GlnK complex reveals how GlnK regulates the ammonia channel"
4604:
2426:
2193:
4295:
157:
2822:
4564:
4196:
1925:
1350:
Javelle, Arnaud; Lupo, Domenico; Zheng, Lei; Li, Xiao-Dan; Winkler, Fritz K.; Merrick, Mike (2006-12-22).
597:
430:
268:
4540:
4376:
4062:
3247:
3172:
2566:
2437:
2432:
2006:
1608:
1352:"An unusual twin-his arrangement in the pore of ammonia channels is essential for substrate conductance"
247:
237:
225:
153:
1240:
Fong, Rebecca N.; Kim, Kwang-Seo; Yoshihara, Corinne; Inwood, William B.; Kustu, Sydney (2007-11-20).
897:
Conroy MJ, Jamieson SJ, Blakey D, Kaufmann T, Engel A, Fotiadis D, Merrick M, Bullough PA (Dec 2004).
4637:
4632:
2599:
2001:
1502:
1253:
1067:
1000:
855:
757:
663:
292:
602:
1935:
1710:
805:"The rhesus protein RhCG: a new perspective in ammonium transport and distal urinary acidification"
1178:
von
Wittgenstein, Neil J. J. B.; Le, Cuong H.; Hawkins, Barbara J.; Ehlting, Jürgen (2014-01-01).
1991:
1160:
879:
623:
561:
413:
discuss these mechanisms in light of functional and simulation studies on the AmtB transporter.
652:"The mechanism of ammonia transport based on the crystal structure of AmtB of Escherichia coli"
351:
The generalized transport reaction catalyzed by members of the Amt family are suggested to be:
4132:
4127:
3475:
3470:
3397:
3392:
3387:
3382:
3377:
3372:
3352:
3347:
3342:
3337:
3322:
3312:
3302:
3297:
3287:
3262:
3068:
3053:
3048:
2670:
2665:
2660:
1530:
1465:
1424:
1416:
1381:
1373:
1332:
1324:
1289:
1271:
1219:
1201:
1152:
1144:
1103:
1085:
1036:
1018:
969:
928:
871:
827:
785:
726:
691:
615:
553:
518:
144:
31:
4386:
4353:
4320:
4310:
4277:
4272:
4206:
4087:
4039:
4029:
3986:
3950:
3945:
3912:
3907:
3902:
3897:
3888:
3883:
3878:
3850:
3840:
3831:
3826:
3821:
3656:
3641:
3636:
3621:
3588:
3555:
3465:
3425:
3182:
3154:
3139:
3134:
3129:
3106:
3101:
2949:
2945:
2936:
2894:
2718:
2708:
2698:
2630:
2576:
2510:
2495:
2329:
2324:
2319:
2170:
2071:
2066:
2036:
1960:
1955:
1950:
1877:
4432:
2533:
2271:
2261:
2246:
2208:
2203:
2021:
1945:
1872:
1597:
1520:
1510:
1455:
1408:
1363:
1316:
1279:
1261:
1209:
1191:
1134:
1093:
1075:
1026:
1008:
959:
918:
910:
863:
819:
775:
765:
718:
681:
671:
607:
545:
508:
498:
402:
242:
1180:"Evolutionary classification of ammonium, nitrate, and peptide transporters in land plants"
136:
4516:
1601:
376:
long, in which electronic density was observed in the crystallographic study of AmtB from
1506:
1257:
1071:
1004:
859:
761:
667:
1525:
1490:
1284:
1241:
1214:
1179:
1098:
1055:
923:
898:
780:
745:
513:
486:
1031:
988:
686:
651:
98:
4672:
4532:
964:
947:
883:
1164:
627:
565:
62:
1489:
Conroy MJ, Durand A, Lupo D, Li XD, Bullough PA, Winkler FK, Merrick M (Jan 2007).
1054:
Musa-Aziz, Raif; Chen, Li-Ming; Pelletier, Marc F.; Boron, Walter F. (2009-03-31).
132:
1551:
185:
110:
86:
1412:
770:
746:"Functional reconstitution into liposomes of purified human RhCG ammonia channel"
74:
4155:
3611:
3207:
2408:
899:"Electron and atomic force microscopy of the trimeric ammonium transporter AmtB"
454:
263:
255:
233:
1495:
Proceedings of the
National Academy of Sciences of the United States of America
1246:
Proceedings of the
National Academy of Sciences of the United States of America
1060:
Proceedings of the
National Academy of Sciences of the United States of America
993:
Proceedings of the
National Academy of Sciences of the United States of America
722:
656:
Proceedings of the
National Academy of Sciences of the United States of America
4591:
3749:
1139:
1122:
549:
462:
332:
328:
276:
259:
229:
1420:
1377:
1328:
1275:
1205:
1148:
1089:
1022:
914:
240:. The three-dimensional structure of the ammonia transport protein AmtB from
4528:
1515:
1483:
1266:
1196:
1080:
676:
644:
611:
582:
503:
35:
1534:
1469:
1460:
1443:
1428:
1385:
1368:
1351:
1336:
1293:
1223:
1156:
1107:
1040:
1013:
973:
932:
875:
831:
789:
730:
695:
619:
557:
522:
4122:
4117:
4112:
4044:
3661:
3402:
3367:
3362:
3357:
3332:
3327:
3317:
3307:
3292:
3282:
3277:
3267:
3257:
3252:
3242:
3232:
3227:
3222:
3063:
3058:
3043:
3038:
3033:
3028:
3023:
3018:
2788:
2655:
1982:
435:
313:
209:
197:
69:
867:
823:
4489:
4484:
4479:
4474:
4469:
4464:
4414:
4409:
4381:
4358:
4348:
4343:
4315:
4305:
4300:
4267:
4211:
4201:
4107:
4102:
4097:
4092:
4082:
4077:
4072:
4067:
4034:
4024:
4019:
4014:
3991:
3981:
3976:
3953:
3940:
3935:
3869:
3864:
3855:
3845:
3816:
3811:
3788:
3783:
3778:
3755:
3731:
3708:
3651:
3646:
3631:
3626:
3616:
3593:
3583:
3578:
3550:
3545:
3523:
3518:
3513:
3508:
3503:
3498:
3460:
3455:
3450:
3445:
3440:
3435:
3430:
3217:
3212:
3202:
3197:
3192:
3187:
3177:
3149:
3144:
3096:
3091:
3013:
3008:
3003:
2998:
2993:
2988:
2983:
2978:
2973:
2931:
2922:
2913:
2908:
2899:
2889:
2884:
2879:
2833:
2828:
2804:
2799:
2794:
2733:
2728:
2723:
2713:
2703:
2693:
2625:
2581:
2571:
2543:
2538:
2515:
2505:
2500:
2472:
2467:
2462:
2457:
2405:
2400:
2356:
2351:
2346:
2341:
2334:
2314:
2309:
2304:
2281:
2276:
2175:
2165:
2160:
2086:
2081:
2076:
2061:
2056:
2051:
2046:
2041:
1882:
1780:
1775:
1770:
1765:
1760:
251:
1320:
25:
4613:
3702:
3237:
2784:
2266:
2256:
2251:
2241:
2236:
2231:
2198:
2155:
2150:
2145:
2140:
2122:
2117:
2112:
2107:
2031:
2026:
2016:
2011:
1978:
1940:
1930:
1920:
1915:
1905:
1867:
1862:
1857:
1852:
1847:
1842:
1837:
1832:
1809:
1804:
1755:
1745:
1740:
1682:
1677:
1667:
1662:
272:
201:
164:
1056:"Relative CO2/NH3 selectivities of AQP1, AQP4, AQP5, AmtB, and RhAG"
803:
Wagner CA, Devuyst O, Belge H, Bourgeois S, Houillier P (Jan 2011).
323:, may be the substrate of AmtB, but controversy still exists. If NH
2761:
2756:
1910:
1750:
1735:
1730:
1725:
1720:
1715:
205:
335:
process with K, and that one histidine removes a proton off of NH
4244:
4239:
4234:
2135:
458:
450:
446:
373:
221:
217:
213:
126:
81:
57:
4514:
4453:
4178:
4010:
System A & N, sodium-coupled neutral amino-acid transporter
3684:
2856:
2377:
1639:
1624:
1570:
650:
Zheng L, Kostrewa D, Bernèche S, Winkler FK, Li XD (Dec 2004).
1557:
Creative
Commons Attribution-ShareAlike 3.0 Unported License
1658:
high affinity glutamate and neutral amino-acid transporter
1555:, which is licensed in a way that permits reuse under the
487:"Function of human Rh based on structure of RhCG at 2.1 A"
989:"Rhesus expression in a green alga is regulated by CO(2)"
2104:
cationic amino-acid transporter/glycoprotein-associated
2129:
glycoprotein-associated/light or catalytic subunits of
1546:
946:
Thornton J, Blakey D, Scanlon E, Merrick M (May 2006).
1552:"1.A.11 The Ammonium Channel Transporter (Amt) Family"
1123:"The Amt/Mep/Rh family of ammonium transport proteins"
4263:
Na-independent, system-L like amino-acid transporter
1121:
Andrade, Susana L. A.; Einsle, Oliver (2007-12-01).
4590:
4527:
4425:
4397:
4369:
4331:
4288:
4255:
4222:
4189:
4143:
4055:
4002:
3964:
3923:
3799:
3766:
3742:
3719:
3695:
3604:
3566:
3534:
3486:
3413:
3165:
3117:
3079:
2961:
2867:
2815:
2777:
2744:
2681:
2592:
2554:
2526:
2483:
2419:
2388:
2292:
2219:
2186:
2097:
1971:
1893:
1820:
1791:
1703:
1650:
163:
143:
125:
120:
104:
92:
80:
68:
56:
48:
43:
18:
491:Proceedings of the National Academy of Sciences
639:
637:
577:
575:
204:, methylammonium/ammonium permeases (MEPs) in
1582:
438:residue which sterically blocks the channel.
8:
480:
478:
476:
2969:organic cation/anion/zwitterion transporter
4524:
4511:
4450:
4186:
4175:
3692:
3681:
2864:
2853:
2491:human Na-sulfate/carboxylate cotransporter
2385:
2374:
1647:
1636:
1632:
1621:
1589:
1575:
1567:
442:Human ammonia transporter-related proteins
287:The structure of the ammonia channel from
117:
24:
1524:
1514:
1459:
1367:
1283:
1265:
1213:
1195:
1138:
1097:
1079:
1030:
1012:
963:
922:
779:
769:
685:
675:
601:
512:
502:
1309:Journal of the American Chemical Society
3087:Na+-dependent ascorbic acid transporter
472:
327:is transported, K possibly serves as a
2875:Organic anion-transporting polypeptide
1563:. All relevant terms must be followed.
258:Rh complex is a heterotrimer of RhAG,
15:
3931:proton-coupled amino-acid transporter
2131:heterodimeric amino-acid transporters
1800:heterodimeric amino-acid transporters
1235:
1233:
7:
2396:proton coupled metal ion transporter
3972:sugar-phosphate/phosphate exchanger
3574:facilitative nucleoside transporter
1448:The Journal of Biological Chemistry
1356:The Journal of Biological Chemistry
3774:type II Na-phosphate cotransporter
1987:sodium:neurotransmitter symporters
1401:Transfusion Clinique et Biologique
14:
3727:Vesicular glutamate transporter 1
2689:Vesicular glutamate transporter 1
2562:proton oligopeptide cotransporter
1549:, this article uses content from
1442:Durand A, Merrick M (Oct 2006).
965:10.1111/j.1574-6968.2006.00202.x
3542:Na-coupled nucleoside transport
3421:multifunctional anion exchanger
2752:vesicular monoamine transporter
1:
4405:multidrug and toxin extrusion
3494:fatty acid transport proteins
1711:facilitative GLUT transporter
208:, or Rhesus (Rh) proteins in
121:Available protein structures:
30:Human Rhesus C Glycoprotein.
4151:basolateral iron transporter
3807:nucleoside-sugar transporter
2300:sodium bile salt cotransport
1901:sodium glucose cotransporter
1413:10.1016/j.tracli.2010.06.004
771:10.1371/journal.pone.0008921
1606:membrane transport proteins
224:Rhesus proteins constitute
190:membrane transport proteins
188:) are structurally related
4695:
4339:Putative sugar transporter
1127:Molecular Membrane Biology
723:10.1152/physiol.00051.2005
196:(ammonia transporters) in
4654:
4523:
4510:
4460:
4449:
4185:
4174:
3691:
3680:
2863:
2852:
2384:
2373:
1646:
1635:
1631:
1620:
1140:10.1080/09687680701388423
952:FEMS Microbiology Letters
550:10.1007/s00424-003-1142-8
116:
23:
4659:solute carrier disorders
4296:Choline-like transporter
2427:electroneutral cation-Cl
1184:BMC Evolutionary Biology
915:10.1038/sj.embor.7400296
250:revealing a hydrophobic
4197:Magnesium transporter E
1828:bicarbonate transporter
1516:10.1073/pnas.0610348104
1267:10.1073/pnas.0709267104
1197:10.1186/1471-2148-14-11
1081:10.1073/pnas.0813231106
677:10.1073/pnas.0406475101
612:10.1126/science.1101952
504:10.1073/pnas.1003587107
397:/H, the transport of NH
246:has been determined by
4592:Antiporter (exchanger)
1461:10.1074/jbc.M602477200
1369:10.1074/jbc.M608325200
1014:10.1073/pnas.112225599
293:transmembrane segments
4679:Solute carrier family
4063:metal ion transporter
3173:mitochondrial carrier
2823:type III Na-phosphate
303:Substrate specificity
248:x-ray crystallography
238:Rh blood group system
226:solute carrier family
1559:, but not under the
812:Kidney International
393:, the antiport of NH
182:Ammonia transporters
4230:Ammonia transporter
3125:Na/(Ca-K) exchanger
1507:2007PNAS..104.1213C
1362:(51): 39492–39498.
1258:2007PNAS..10418706F
1252:(47): 18706–18711.
1072:2009PNAS..106.5406M
1005:2002PNAS...99.7769S
868:10.1038/nature07518
860:2008Natur.456..339B
824:10.1038/ki.2010.386
762:2010PLoSO...5.8921M
668:2004PNAS..10117090Z
19:Ammonia transporter
4377:Folate transporter
1798:heavy subunits of
347:Transport reaction
4666:
4665:
4650:
4649:
4646:
4645:
4506:
4505:
4502:
4501:
4498:
4497:
4445:
4444:
4441:
4440:
4170:
4169:
4166:
4165:
3676:
3675:
3672:
3671:
2848:
2847:
2844:
2843:
2369:
2368:
2365:
2364:
1598:Membrane proteins
1321:10.1021/ja066208n
1066:(13): 5406–5411.
999:(11): 7769–7773.
596:(5690): 1587–94.
497:(21): 9638–9643.
212:. In humans, the
179:
178:
175:
174:
170:structure summary
4686:
4625:
4624:
4623:
4525:
4512:
4451:
4433:Heme transporter
4187:
4176:
3693:
3682:
2865:
2854:
2534:urea transporter
2386:
2375:
1648:
1637:
1633:
1622:
1602:carrier proteins
1591:
1584:
1577:
1568:
1539:
1538:
1528:
1518:
1486:
1480:
1474:
1473:
1463:
1454:(40): 29558–67.
1439:
1433:
1432:
1396:
1390:
1389:
1371:
1347:
1341:
1340:
1315:(5): 1210–1215.
1304:
1298:
1297:
1287:
1269:
1237:
1228:
1227:
1217:
1199:
1175:
1169:
1168:
1142:
1133:(5–6): 357–365.
1118:
1112:
1111:
1101:
1083:
1051:
1045:
1044:
1034:
1016:
984:
978:
977:
967:
943:
937:
936:
926:
894:
888:
887:
854:(7220): 339–43.
842:
836:
835:
809:
800:
794:
793:
783:
773:
741:
735:
734:
706:
700:
699:
689:
679:
647:
641:
632:
631:
605:
585:
579:
570:
569:
533:
527:
526:
516:
506:
482:
378:Escherichia coli
319:, rather than NH
243:Escherichia coli
118:
38:
28:
16:
4694:
4693:
4689:
4688:
4687:
4685:
4684:
4683:
4669:
4668:
4667:
4662:
4642:
4622:
4619:
4618:
4617:
4615:
4586:
4549:
4519:
4494:
4456:
4437:
4421:
4393:
4365:
4327:
4284:
4251:
4218:
4181:
4162:
4139:
4051:
3998:
3960:
3919:
3795:
3762:
3738:
3715:
3687:
3668:
3600:
3562:
3530:
3482:
3409:
3161:
3113:
3075:
2957:
2859:
2840:
2811:
2773:
2740:
2677:
2600:monocarboxylate
2588:
2550:
2522:
2479:
2415:
2380:
2361:
2288:
2215:
2194:Na/Ca exchanger
2182:
2093:
1967:
1889:
1816:
1787:
1699:
1642:
1627:
1616:
1595:
1542:
1488:
1482:
1481:
1477:
1441:
1440:
1436:
1398:
1397:
1393:
1349:
1348:
1344:
1306:
1305:
1301:
1239:
1238:
1231:
1177:
1176:
1172:
1120:
1119:
1115:
1053:
1052:
1048:
986:
985:
981:
945:
944:
940:
896:
895:
891:
844:
843:
839:
807:
802:
801:
797:
743:
742:
738:
708:
707:
703:
662:(49): 17090–5.
649:
643:
642:
635:
603:10.1.1.133.6480
587:
581:
580:
573:
538:Pflügers Archiv
535:
534:
530:
484:
483:
474:
470:
444:
419:
408:
400:
396:
392:
388:
383:
370:
362:
358:
349:
342:
338:
326:
322:
317:
305:
285:
94:OPM superfamily
39:
34:
12:
11:
5:
4692:
4690:
4682:
4681:
4671:
4670:
4664:
4663:
4655:
4652:
4651:
4648:
4647:
4644:
4643:
4641:
4640:
4635:
4630:
4629:
4628:
4620:
4602:
4596:
4594:
4588:
4587:
4585:
4584:
4583:
4582:
4577:
4567:
4562:
4557:
4552:
4547:
4543:
4537:
4535:
4521:
4520:
4515:
4508:
4507:
4504:
4503:
4500:
4499:
4496:
4495:
4493:
4492:
4487:
4482:
4477:
4472:
4467:
4461:
4458:
4457:
4454:
4447:
4446:
4443:
4442:
4439:
4438:
4436:
4435:
4429:
4427:
4423:
4422:
4420:
4419:
4418:
4417:
4412:
4401:
4399:
4395:
4394:
4392:
4391:
4390:
4389:
4384:
4373:
4371:
4367:
4366:
4364:
4363:
4362:
4361:
4356:
4351:
4346:
4335:
4333:
4329:
4328:
4326:
4325:
4324:
4323:
4318:
4313:
4308:
4303:
4292:
4290:
4286:
4285:
4283:
4282:
4281:
4280:
4275:
4270:
4259:
4257:
4253:
4252:
4250:
4249:
4248:
4247:
4242:
4237:
4226:
4224:
4220:
4219:
4217:
4216:
4215:
4214:
4209:
4204:
4193:
4191:
4183:
4182:
4179:
4172:
4171:
4168:
4167:
4164:
4163:
4161:
4160:
4159:
4158:
4147:
4145:
4141:
4140:
4138:
4137:
4136:
4135:
4130:
4125:
4120:
4115:
4110:
4105:
4100:
4095:
4090:
4085:
4080:
4075:
4070:
4059:
4057:
4053:
4052:
4050:
4049:
4048:
4047:
4042:
4037:
4032:
4027:
4022:
4017:
4006:
4004:
4000:
3999:
3997:
3996:
3995:
3994:
3989:
3984:
3979:
3968:
3966:
3962:
3961:
3959:
3958:
3957:
3956:
3948:
3943:
3938:
3927:
3925:
3921:
3920:
3918:
3917:
3916:
3915:
3910:
3905:
3900:
3893:
3892:
3891:
3886:
3881:
3874:
3873:
3872:
3867:
3860:
3859:
3858:
3853:
3848:
3843:
3836:
3835:
3834:
3829:
3824:
3819:
3814:
3803:
3801:
3797:
3796:
3794:
3793:
3792:
3791:
3786:
3781:
3770:
3768:
3764:
3763:
3761:
3760:
3759:
3758:
3746:
3744:
3740:
3739:
3737:
3736:
3735:
3734:
3723:
3721:
3717:
3716:
3714:
3713:
3712:
3711:
3699:
3697:
3689:
3688:
3685:
3678:
3677:
3674:
3673:
3670:
3669:
3667:
3666:
3665:
3664:
3659:
3654:
3649:
3644:
3639:
3634:
3629:
3624:
3619:
3608:
3606:
3602:
3601:
3599:
3598:
3597:
3596:
3591:
3586:
3581:
3570:
3568:
3564:
3563:
3561:
3560:
3559:
3558:
3553:
3538:
3536:
3532:
3531:
3529:
3528:
3527:
3526:
3521:
3516:
3511:
3506:
3501:
3490:
3488:
3484:
3483:
3481:
3480:
3479:
3478:
3473:
3468:
3463:
3458:
3453:
3448:
3443:
3438:
3433:
3428:
3417:
3415:
3411:
3410:
3408:
3407:
3406:
3405:
3400:
3395:
3390:
3385:
3380:
3375:
3370:
3365:
3360:
3355:
3350:
3345:
3340:
3335:
3330:
3325:
3320:
3315:
3310:
3305:
3300:
3295:
3290:
3285:
3280:
3275:
3270:
3265:
3260:
3255:
3250:
3245:
3240:
3235:
3230:
3225:
3220:
3215:
3210:
3205:
3200:
3195:
3190:
3185:
3180:
3169:
3167:
3163:
3162:
3160:
3159:
3158:
3157:
3152:
3147:
3142:
3137:
3132:
3121:
3119:
3115:
3114:
3112:
3111:
3110:
3109:
3104:
3099:
3094:
3083:
3081:
3077:
3076:
3074:
3073:
3072:
3071:
3066:
3061:
3056:
3051:
3046:
3041:
3036:
3031:
3026:
3021:
3016:
3011:
3006:
3001:
2996:
2991:
2986:
2981:
2976:
2965:
2963:
2959:
2958:
2956:
2955:
2954:
2953:
2941:
2940:
2939:
2934:
2927:
2926:
2925:
2918:
2917:
2916:
2911:
2904:
2903:
2902:
2897:
2892:
2887:
2882:
2871:
2869:
2861:
2860:
2857:
2850:
2849:
2846:
2845:
2842:
2841:
2839:
2838:
2837:
2836:
2831:
2825:cotransporter
2819:
2817:
2813:
2812:
2810:
2809:
2808:
2807:
2802:
2797:
2781:
2779:
2775:
2774:
2772:
2771:
2770:
2769:
2764:
2759:
2748:
2746:
2742:
2741:
2739:
2738:
2737:
2736:
2731:
2726:
2721:
2716:
2711:
2706:
2701:
2696:
2685:
2683:
2679:
2678:
2676:
2675:
2674:
2673:
2668:
2663:
2658:
2653:
2648:
2643:
2638:
2633:
2628:
2623:
2618:
2613:
2608:
2596:
2594:
2590:
2589:
2587:
2586:
2585:
2584:
2579:
2574:
2569:
2558:
2556:
2552:
2551:
2549:
2548:
2547:
2546:
2541:
2530:
2528:
2524:
2523:
2521:
2520:
2519:
2518:
2513:
2508:
2503:
2498:
2487:
2485:
2481:
2480:
2478:
2477:
2476:
2475:
2470:
2465:
2460:
2455:
2450:
2445:
2440:
2435:
2429:cotransporter
2423:
2421:
2417:
2416:
2414:
2413:
2412:
2411:
2403:
2392:
2390:
2382:
2381:
2378:
2371:
2370:
2367:
2366:
2363:
2362:
2360:
2359:
2354:
2349:
2344:
2339:
2338:
2337:
2332:
2327:
2322:
2317:
2312:
2307:
2296:
2294:
2290:
2289:
2287:
2286:
2285:
2284:
2279:
2274:
2269:
2264:
2259:
2254:
2249:
2244:
2239:
2234:
2227:Na/H exchanger
2223:
2221:
2217:
2216:
2214:
2213:
2212:
2211:
2206:
2201:
2190:
2188:
2184:
2183:
2181:
2180:
2179:
2178:
2173:
2168:
2163:
2158:
2153:
2148:
2143:
2138:
2127:
2126:
2125:
2120:
2115:
2110:
2101:
2099:
2095:
2094:
2092:
2091:
2090:
2089:
2084:
2079:
2074:
2069:
2064:
2059:
2054:
2049:
2044:
2039:
2034:
2029:
2024:
2019:
2014:
2009:
2004:
1999:
1994:
1975:
1973:
1969:
1968:
1966:
1965:
1964:
1963:
1958:
1953:
1948:
1943:
1938:
1933:
1928:
1923:
1918:
1913:
1908:
1897:
1895:
1891:
1890:
1888:
1887:
1886:
1885:
1880:
1875:
1870:
1865:
1860:
1855:
1850:
1845:
1840:
1835:
1824:
1822:
1818:
1817:
1815:
1814:
1813:
1812:
1807:
1795:
1793:
1789:
1788:
1786:
1785:
1784:
1783:
1778:
1773:
1768:
1763:
1758:
1753:
1748:
1743:
1738:
1733:
1728:
1723:
1718:
1707:
1705:
1701:
1700:
1698:
1697:
1696:
1695:
1690:
1685:
1680:
1675:
1670:
1665:
1654:
1652:
1644:
1643:
1640:
1629:
1628:
1625:
1618:
1617:
1609:solute carrier
1596:
1594:
1593:
1586:
1579:
1571:
1541:
1540:
1475:
1434:
1407:(3): 168–175.
1391:
1342:
1299:
1229:
1170:
1113:
1046:
979:
938:
909:(12): 1153–8.
889:
837:
795:
736:
701:
633:
571:
528:
471:
469:
466:
443:
440:
418:
415:
409:/H. Lamoureux
406:
398:
394:
390:
386:
381:
369:
366:
365:
364:
360:
356:
348:
345:
340:
336:
324:
320:
315:
304:
301:
284:
281:
269:acid excretion
177:
176:
173:
172:
167:
161:
160:
147:
141:
140:
130:
123:
122:
114:
113:
108:
102:
101:
96:
90:
89:
84:
78:
77:
72:
66:
65:
60:
54:
53:
50:
46:
45:
41:
40:
29:
21:
20:
13:
10:
9:
6:
4:
3:
2:
4691:
4680:
4677:
4676:
4674:
4661:
4660:
4653:
4639:
4636:
4634:
4631:
4627:
4611:
4608:
4607:
4606:
4603:
4601:
4598:
4597:
4595:
4593:
4589:
4581:
4578:
4576:
4573:
4572:
4571:
4568:
4566:
4563:
4561:
4558:
4556:
4553:
4551:
4544:
4542:
4539:
4538:
4536:
4534:
4533:Cotransporter
4530:
4526:
4522:
4518:
4513:
4509:
4491:
4488:
4486:
4483:
4481:
4478:
4476:
4473:
4471:
4468:
4466:
4463:
4462:
4459:
4452:
4448:
4434:
4431:
4430:
4428:
4424:
4416:
4413:
4411:
4408:
4407:
4406:
4403:
4402:
4400:
4396:
4388:
4385:
4383:
4380:
4379:
4378:
4375:
4374:
4372:
4368:
4360:
4357:
4355:
4352:
4350:
4347:
4345:
4342:
4341:
4340:
4337:
4336:
4334:
4330:
4322:
4319:
4317:
4314:
4312:
4309:
4307:
4304:
4302:
4299:
4298:
4297:
4294:
4293:
4291:
4287:
4279:
4276:
4274:
4271:
4269:
4266:
4265:
4264:
4261:
4260:
4258:
4254:
4246:
4243:
4241:
4238:
4236:
4233:
4232:
4231:
4228:
4227:
4225:
4221:
4213:
4210:
4208:
4205:
4203:
4200:
4199:
4198:
4195:
4194:
4192:
4188:
4184:
4177:
4173:
4157:
4154:
4153:
4152:
4149:
4148:
4146:
4142:
4134:
4131:
4129:
4126:
4124:
4121:
4119:
4116:
4114:
4111:
4109:
4106:
4104:
4101:
4099:
4096:
4094:
4091:
4089:
4086:
4084:
4081:
4079:
4076:
4074:
4071:
4069:
4066:
4065:
4064:
4061:
4060:
4058:
4054:
4046:
4043:
4041:
4038:
4036:
4033:
4031:
4028:
4026:
4023:
4021:
4018:
4016:
4013:
4012:
4011:
4008:
4007:
4005:
4001:
3993:
3990:
3988:
3985:
3983:
3980:
3978:
3975:
3974:
3973:
3970:
3969:
3967:
3963:
3955:
3952:
3949:
3947:
3944:
3942:
3939:
3937:
3934:
3933:
3932:
3929:
3928:
3926:
3922:
3914:
3911:
3909:
3906:
3904:
3901:
3899:
3896:
3895:
3894:
3890:
3887:
3885:
3882:
3880:
3877:
3876:
3875:
3871:
3868:
3866:
3863:
3862:
3861:
3857:
3854:
3852:
3849:
3847:
3844:
3842:
3839:
3838:
3837:
3833:
3830:
3828:
3825:
3823:
3820:
3818:
3815:
3813:
3810:
3809:
3808:
3805:
3804:
3802:
3798:
3790:
3787:
3785:
3782:
3780:
3777:
3776:
3775:
3772:
3771:
3769:
3765:
3757:
3754:
3753:
3751:
3748:
3747:
3745:
3741:
3733:
3730:
3729:
3728:
3725:
3724:
3722:
3718:
3710:
3707:
3706:
3704:
3701:
3700:
3698:
3694:
3690:
3683:
3679:
3663:
3660:
3658:
3655:
3653:
3650:
3648:
3645:
3643:
3640:
3638:
3635:
3633:
3630:
3628:
3625:
3623:
3620:
3618:
3615:
3614:
3613:
3610:
3609:
3607:
3603:
3595:
3592:
3590:
3587:
3585:
3582:
3580:
3577:
3576:
3575:
3572:
3571:
3569:
3565:
3557:
3554:
3552:
3549:
3548:
3547:
3543:
3540:
3539:
3537:
3533:
3525:
3522:
3520:
3517:
3515:
3512:
3510:
3507:
3505:
3502:
3500:
3497:
3496:
3495:
3492:
3491:
3489:
3485:
3477:
3474:
3472:
3469:
3467:
3464:
3462:
3459:
3457:
3454:
3452:
3449:
3447:
3444:
3442:
3439:
3437:
3434:
3432:
3429:
3427:
3424:
3423:
3422:
3419:
3418:
3416:
3412:
3404:
3401:
3399:
3396:
3394:
3391:
3389:
3386:
3384:
3381:
3379:
3376:
3374:
3371:
3369:
3366:
3364:
3361:
3359:
3356:
3354:
3351:
3349:
3346:
3344:
3341:
3339:
3336:
3334:
3331:
3329:
3326:
3324:
3321:
3319:
3316:
3314:
3311:
3309:
3306:
3304:
3301:
3299:
3296:
3294:
3291:
3289:
3286:
3284:
3281:
3279:
3276:
3274:
3271:
3269:
3266:
3264:
3261:
3259:
3256:
3254:
3251:
3249:
3246:
3244:
3241:
3239:
3236:
3234:
3231:
3229:
3226:
3224:
3221:
3219:
3216:
3214:
3211:
3209:
3206:
3204:
3201:
3199:
3196:
3194:
3191:
3189:
3186:
3184:
3181:
3179:
3176:
3175:
3174:
3171:
3170:
3168:
3164:
3156:
3153:
3151:
3148:
3146:
3143:
3141:
3138:
3136:
3133:
3131:
3128:
3127:
3126:
3123:
3122:
3120:
3116:
3108:
3105:
3103:
3100:
3098:
3095:
3093:
3090:
3089:
3088:
3085:
3084:
3082:
3078:
3070:
3067:
3065:
3062:
3060:
3057:
3055:
3052:
3050:
3047:
3045:
3042:
3040:
3037:
3035:
3032:
3030:
3027:
3025:
3022:
3020:
3017:
3015:
3012:
3010:
3007:
3005:
3002:
3000:
2997:
2995:
2992:
2990:
2987:
2985:
2982:
2980:
2977:
2975:
2972:
2971:
2970:
2967:
2966:
2964:
2960:
2951:
2947:
2944:
2943:
2942:
2938:
2935:
2933:
2930:
2929:
2928:
2924:
2921:
2920:
2919:
2915:
2912:
2910:
2907:
2906:
2905:
2901:
2898:
2896:
2893:
2891:
2888:
2886:
2883:
2881:
2878:
2877:
2876:
2873:
2872:
2870:
2866:
2862:
2855:
2851:
2835:
2832:
2830:
2827:
2826:
2824:
2821:
2820:
2818:
2814:
2806:
2803:
2801:
2798:
2796:
2793:
2792:
2790:
2786:
2783:
2782:
2780:
2776:
2768:
2765:
2763:
2760:
2758:
2755:
2754:
2753:
2750:
2749:
2747:
2743:
2735:
2732:
2730:
2727:
2725:
2722:
2720:
2717:
2715:
2712:
2710:
2707:
2705:
2702:
2700:
2697:
2695:
2692:
2691:
2690:
2687:
2686:
2684:
2680:
2672:
2669:
2667:
2664:
2662:
2659:
2657:
2654:
2652:
2649:
2647:
2644:
2642:
2639:
2637:
2634:
2632:
2629:
2627:
2624:
2622:
2619:
2617:
2614:
2612:
2609:
2607:
2604:
2603:
2601:
2598:
2597:
2595:
2591:
2583:
2580:
2578:
2575:
2573:
2570:
2568:
2565:
2564:
2563:
2560:
2559:
2557:
2553:
2545:
2542:
2540:
2537:
2536:
2535:
2532:
2531:
2529:
2525:
2517:
2514:
2512:
2509:
2507:
2504:
2502:
2499:
2497:
2494:
2493:
2492:
2489:
2488:
2486:
2482:
2474:
2471:
2469:
2466:
2464:
2461:
2459:
2456:
2454:
2451:
2449:
2446:
2444:
2441:
2439:
2436:
2434:
2431:
2430:
2428:
2425:
2424:
2422:
2418:
2410:
2407:
2404:
2402:
2399:
2398:
2397:
2394:
2393:
2391:
2387:
2383:
2376:
2372:
2358:
2355:
2353:
2350:
2348:
2345:
2343:
2340:
2336:
2333:
2331:
2328:
2326:
2323:
2321:
2318:
2316:
2313:
2311:
2308:
2306:
2303:
2302:
2301:
2298:
2297:
2295:
2291:
2283:
2280:
2278:
2275:
2273:
2270:
2268:
2265:
2263:
2260:
2258:
2255:
2253:
2250:
2248:
2245:
2243:
2240:
2238:
2235:
2233:
2230:
2229:
2228:
2225:
2224:
2222:
2218:
2210:
2207:
2205:
2202:
2200:
2197:
2196:
2195:
2192:
2191:
2189:
2185:
2177:
2174:
2172:
2169:
2167:
2164:
2162:
2159:
2157:
2154:
2152:
2149:
2147:
2144:
2142:
2139:
2137:
2134:
2133:
2132:
2128:
2124:
2121:
2119:
2116:
2114:
2111:
2109:
2106:
2105:
2103:
2102:
2100:
2096:
2088:
2085:
2083:
2080:
2078:
2075:
2073:
2070:
2068:
2065:
2063:
2060:
2058:
2055:
2053:
2050:
2048:
2045:
2043:
2040:
2038:
2035:
2033:
2030:
2028:
2025:
2023:
2020:
2018:
2015:
2013:
2010:
2008:
2005:
2003:
2000:
1998:
1995:
1993:
1990:
1989:
1988:
1984:
1980:
1977:
1976:
1974:
1970:
1962:
1959:
1957:
1954:
1952:
1949:
1947:
1944:
1942:
1939:
1937:
1934:
1932:
1929:
1927:
1924:
1922:
1919:
1917:
1914:
1912:
1909:
1907:
1904:
1903:
1902:
1899:
1898:
1896:
1892:
1884:
1881:
1879:
1876:
1874:
1871:
1869:
1866:
1864:
1861:
1859:
1856:
1854:
1851:
1849:
1846:
1844:
1841:
1839:
1836:
1834:
1831:
1830:
1829:
1826:
1825:
1823:
1819:
1811:
1808:
1806:
1803:
1802:
1801:
1797:
1796:
1794:
1790:
1782:
1779:
1777:
1774:
1772:
1769:
1767:
1764:
1762:
1759:
1757:
1754:
1752:
1749:
1747:
1744:
1742:
1739:
1737:
1734:
1732:
1729:
1727:
1724:
1722:
1719:
1717:
1714:
1713:
1712:
1709:
1708:
1706:
1702:
1694:
1691:
1689:
1686:
1684:
1681:
1679:
1676:
1674:
1671:
1669:
1666:
1664:
1661:
1660:
1659:
1656:
1655:
1653:
1649:
1645:
1638:
1634:
1630:
1623:
1619:
1614:
1610:
1607:
1603:
1599:
1592:
1587:
1585:
1580:
1578:
1573:
1572:
1569:
1565:
1564:
1562:
1558:
1553:
1550:
1548:
1536:
1532:
1527:
1522:
1517:
1512:
1508:
1504:
1501:(4): 1213–8.
1500:
1496:
1492:
1485:
1479:
1476:
1471:
1467:
1462:
1457:
1453:
1449:
1445:
1438:
1435:
1430:
1426:
1422:
1418:
1414:
1410:
1406:
1402:
1395:
1392:
1387:
1383:
1379:
1375:
1370:
1365:
1361:
1357:
1353:
1346:
1343:
1338:
1334:
1330:
1326:
1322:
1318:
1314:
1310:
1303:
1300:
1295:
1291:
1286:
1281:
1277:
1273:
1268:
1263:
1259:
1255:
1251:
1247:
1243:
1236:
1234:
1230:
1225:
1221:
1216:
1211:
1207:
1203:
1198:
1193:
1189:
1185:
1181:
1174:
1171:
1166:
1162:
1158:
1154:
1150:
1146:
1141:
1136:
1132:
1128:
1124:
1117:
1114:
1109:
1105:
1100:
1095:
1091:
1087:
1082:
1077:
1073:
1069:
1065:
1061:
1057:
1050:
1047:
1042:
1038:
1033:
1028:
1024:
1020:
1015:
1010:
1006:
1002:
998:
994:
990:
983:
980:
975:
971:
966:
961:
958:(1): 114–20.
957:
953:
949:
942:
939:
934:
930:
925:
920:
916:
912:
908:
904:
900:
893:
890:
885:
881:
877:
873:
869:
865:
861:
857:
853:
849:
841:
838:
833:
829:
825:
821:
818:(2): 154–61.
817:
813:
806:
799:
796:
791:
787:
782:
777:
772:
767:
763:
759:
755:
751:
747:
740:
737:
732:
728:
724:
720:
717:(6): 419–29.
716:
712:
705:
702:
697:
693:
688:
683:
678:
673:
669:
665:
661:
657:
653:
646:
640:
638:
634:
629:
625:
621:
617:
613:
609:
604:
599:
595:
591:
584:
578:
576:
572:
567:
563:
559:
555:
551:
547:
544:(5): 807–12.
543:
539:
532:
529:
524:
520:
515:
510:
505:
500:
496:
492:
488:
481:
479:
477:
473:
467:
465:
464:
460:
456:
452:
448:
441:
439:
437:
432:
428:
424:
416:
414:
412:
404:
379:
375:
367:
354:
353:
352:
346:
344:
334:
330:
318:
311:
302:
300:
296:
294:
290:
282:
280:
278:
274:
271:by the mouse
270:
265:
261:
257:
253:
249:
245:
244:
239:
235:
231:
227:
223:
219:
215:
211:
207:
203:
199:
195:
191:
187:
183:
171:
168:
166:
162:
159:
155:
151:
148:
146:
142:
138:
134:
131:
128:
124:
119:
115:
112:
109:
107:
103:
100:
97:
95:
91:
88:
85:
83:
79:
76:
73:
71:
67:
64:
61:
59:
55:
51:
47:
42:
37:
33:
27:
22:
17:
4656:
4229:
3752:transporter
3705:transporter
2791:transporter
2602:transporter
1985:- dependent
1554:
1544:
1543:
1498:
1494:
1478:
1451:
1447:
1437:
1404:
1400:
1394:
1359:
1355:
1345:
1312:
1308:
1302:
1249:
1245:
1187:
1183:
1173:
1130:
1126:
1116:
1063:
1059:
1049:
996:
992:
982:
955:
951:
941:
906:
903:EMBO Reports
902:
892:
851:
847:
840:
815:
811:
798:
756:(1): e8921.
753:
749:
739:
714:
710:
704:
659:
655:
593:
589:
541:
537:
531:
494:
490:
445:
422:
420:
410:
377:
371:
350:
309:
306:
297:
288:
286:
241:
194:Amt proteins
193:
181:
180:
3612:zinc efflux
427:PII protein
403:cotransport
339:to yield NH
329:counter ion
256:erythrocyte
106:OPM protein
44:Identifiers
4638:Cl-oxalate
4633:Cl-formate
4560:Na/glucose
3750:Acetyl-CoA
711:Physiology
468:References
417:Regulation
359:(out) ⇌ NH
277:epididymis
228:42 whilst
186:TC# 1.A.11
133:structures
4657:see also
4529:Symporter
4517:Ion pumps
1547:this edit
1421:1953-8022
1378:0021-9258
1329:0002-7863
1276:1091-6490
1206:1471-2148
1149:0968-7688
1090:1091-6490
1023:0027-8424
884:205215412
598:CiteSeerX
401:, or the
368:Mechanism
283:Structure
236:form the
210:chordates
75:IPR001905
4673:Category
4626:(Band 3)
4610:Na/(Ca-K
4180:SLC41–48
4133:SLC39A14
4128:SLC39A13
4123:SLC39A12
4118:SLC39A11
4113:SLC39A10
4045:SLC38A10
3686:SLC31–40
3662:SLC30A10
3476:SLC26A11
3471:SLC26A10
3403:SLC25A46
3398:SLC25A45
3393:SLC25A44
3388:SLC25A43
3383:SLC25A42
3378:SLC25A41
3373:SLC25A40
3368:SLC25A39
3363:SLC25A38
3358:SLC25A37
3353:SLC25A36
3348:SLC25A35
3343:SLC25A34
3338:SLC25A33
3333:SLC25A32
3328:SLC25A31
3323:SLC25A30
3318:SLC25A29
3313:SLC25A28
3308:SLC25A27
3303:SLC25A26
3298:SLC25A25
3293:SLC25A24
3288:SLC25A23
3283:SLC25A22
3278:SLC25A21
3273:SLC25A20
3268:SLC25A19
3263:SLC25A18
3258:SLC25A17
3253:SLC25A16
3248:SLC25A15
3243:SLC25A14
3238:SLC25A13
3233:SLC25A12
3228:SLC25A11
3223:SLC25A10
3069:SLC22A20
3064:SLC22A19
3059:SLC22A18
3054:SLC22A17
3049:SLC22A16
3044:SLC22A15
3039:SLC22A14
3034:SLC22A13
3029:SLC22A12
3024:SLC22A11
3019:SLC22A10
2858:SLC21–30
2789:thiamine
2671:SLC16A14
2666:SLC16A13
2661:SLC16A12
2656:SLC16A11
2651:SLC16A10
2379:SLC11–20
1983:chloride
1626:By group
1535:17220269
1470:16864585
1429:20674437
1386:17040913
1337:17263403
1294:17998534
1224:24438197
1165:41937253
1157:17710640
1108:19273840
1041:12032358
974:16630265
933:15568015
876:19020613
832:20927037
790:20126667
750:PLOS ONE
731:17119155
696:15563598
628:11436509
620:15361618
566:24601165
558:12920597
523:20457942
436:arginine
333:antiport
198:bacteria
150:RCSB PDB
70:InterPro
4541:Na/K,Cl
4455:SLCO1–4
4415:SLC47A2
4410:SLC47A1
4387:SLC46A2
4382:SLC46A1
4359:SLC45A4
4354:SLC54A3
4349:SLC45A2
4344:SLC45A1
4321:SLC44A5
4316:SLC44A4
4311:SLC44A3
4306:SLC44A2
4301:SLC44A1
4278:SLC43A3
4273:SLC43A2
4268:SLC43A1
4212:SLC41A3
4207:SLC41A2
4202:SLC41A1
4156:SLC40A1
4108:SLC39A9
4103:SLC39A8
4098:SLC39A7
4093:SLC39A6
4088:SLC39A5
4083:SLC39A4
4078:SLC39A3
4073:SLC39A2
4068:SLC39A1
4040:SLC38A6
4035:SLC38A5
4030:SLC38A4
4025:SLC38A3
4020:SLC38A2
4015:SLC38A1
3992:SLC37A4
3987:SLC37A3
3982:SLC37A2
3977:SLC37A1
3951:SLC36A4
3946:SLC36A3
3941:SLC36A2
3936:SLC36A1
3913:SLC35E4
3908:SLC35E3
3903:SLC35E2
3898:SLC35E1
3889:SLC35D3
3884:SLC35D2
3879:SLC35D1
3870:SLC35C2
3865:SLC35C1
3856:SLC35B4
3851:SLC35B3
3846:SLC35B2
3841:SLC35B1
3832:SLC35A5
3827:SLC35A4
3822:SLC35A3
3817:SLC35A2
3812:SLC35A1
3789:SLC34A3
3784:SLC34A2
3779:SLC34A1
3756:SLC33A1
3732:SLC32A1
3709:SLC31A1
3657:SLC30A9
3652:SLC30A8
3647:SLC30A7
3642:SLC30A6
3637:SLC30A5
3632:SLC30A4
3627:SLC30A3
3622:SLC30A2
3617:SLC30A1
3594:SLC29A4
3589:SLC29A3
3584:SLC29A2
3579:SLC29A1
3556:SLC28A3
3551:SLC28A2
3546:SLC28A1
3524:SLC27A6
3519:SLC27A5
3514:SLC27A4
3509:SLC27A3
3504:SLC27A2
3499:SLC27A1
3466:SLC26A9
3461:SLC26A8
3456:SLC26A7
3451:SLC26A6
3446:SLC26A5
3441:SLC26A4
3436:SLC26A3
3431:SLC26A2
3426:SLC26A1
3218:SLC25A9
3213:SLC25A8
3208:SLC25A7
3203:SLC25A6
3198:SLC25A5
3193:SLC25A4
3188:SLC25A3
3183:SLC25A2
3178:SLC25A1
3155:SLC24A6
3150:SLC24A5
3145:SLC24A4
3140:SLC24A3
3135:SLC24A2
3130:SLC24A1
3107:SLC23A4
3102:SLC23A3
3097:SLC23A2
3092:SLC23A1
3014:SLC22A9
3009:SLC22A8
3004:SLC22A7
2999:SLC22A6
2994:SLC22A5
2989:SLC22A4
2984:SLC22A3
2979:SLC22A2
2974:SLC22A1
2950:SLCO6A1
2946:SLCO5A1
2937:SLCO4C1
2932:SLCO4A1
2923:SLCO3A1
2914:SLCO2B1
2909:SLCO2A1
2900:SLCO1C1
2895:SLCO1B4
2890:SLCO1B3
2885:SLCO1B1
2880:SLCO1A2
2834:SLC20A2
2829:SLC20A1
2805:SLC19A3
2800:SLC19A2
2795:SLC19A1
2767:SLC18A3
2762:SLC18A2
2757:SLC18A1
2734:SLC17A9
2729:SLC17A8
2724:SLC17A7
2719:SLC17A6
2714:SLC17A5
2709:SLC17A4
2704:SLC17A3
2699:SLC17A2
2694:SLC17A1
2646:SLC16A9
2641:SLC16A8
2636:SLC16A7
2631:SLC16A6
2626:SLC16A5
2621:SLC16A4
2616:SLC16A3
2611:SLC16A2
2606:SLC16A1
2582:SLC15A4
2577:SLC15A3
2572:SLC15A2
2567:SLC15A1
2544:SLC14A2
2539:SLC14A1
2516:SLC13A5
2511:SLC13A4
2506:SLC13A3
2501:SLC13A2
2496:SLC13A1
2473:SLC12A9
2468:SLC12A8
2463:SLC12A7
2458:SLC12A6
2453:SLC12A5
2448:SLC12A4
2443:SLC12A3
2438:SLC12A2
2433:SLC12A1
2406:SLC11A2
2401:SLC11A1
2335:SLC10A7
2330:SLC10A6
2325:SLC10A5
2320:SLC10A4
2315:SLC10A3
2310:SLC10A2
2305:SLC10A1
2282:SLC9A11
2277:SLC9A10
2176:SLC7A14
2171:SLC7A13
2166:SLC7A11
2161:SLC7A10
2087:SLC6A20
2082:SLC6A19
2077:SLC6A18
2072:SLC6A17
2067:SLC6A16
2062:SLC6A15
2057:SLC6A14
2052:SLC6A13
2047:SLC6A12
2042:SLC6A11
2037:SLC6A10
1641:SLC1–10
1526:1783118
1503:Bibcode
1285:2141841
1254:Bibcode
1215:3922906
1099:2664022
1068:Bibcode
1001:Bibcode
924:1299191
856:Bibcode
781:2812482
758:Bibcode
664:Bibcode
590:Science
514:2906887
423:E. coli
310:E. coli
289:E. coli
252:ammonia
192:called
63:PF00909
3703:copper
2785:folate
2272:SLC9A9
2267:SLC9A8
2262:SLC9A7
2257:SLC9A6
2252:SLC9A5
2247:SLC9A4
2242:SLC9A3
2237:SLC9A2
2232:SLC9A1
2209:SLC8A3
2204:SLC8A2
2199:SLC8A1
2156:SLC7A9
2151:SLC7A8
2146:SLC7A7
2141:SLC7A6
2136:SLC7A5
2123:SLC7A4
2118:SLC7A3
2113:SLC7A2
2108:SLC7A1
2032:SLC6A9
2027:SLC6A8
2022:SLC6A7
2017:SLC6A6
2012:SLC6A5
2007:SLC6A4
2002:SLC6A3
1997:SLC6A2
1992:SLC6A1
1981:- and
1979:sodium
1906:SLC5A1
1833:SLC4A1
1805:SLC3A1
1716:SLC2A1
1663:SLC1A1
1545:As of
1533:
1523:
1468:
1427:
1419:
1384:
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1292:
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1222:
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411:et al.
331:in an
273:kidney
262:, and
220:, and
202:plants
165:PDBsum
139:
129:
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49:Symbol
4605:Na/Ca
4555:Na/Cl
4426:(48):
4398:(47):
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4256:(43):
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880:S2CID
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624:S2CID
562:S2CID
405:of NH
206:yeast
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4565:Na/I
4546:Na/P
4490:O4A1
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4470:O1B1
4465:O1A2
4245:RhCG
4240:RhBG
4235:RhAG
3954:36A2
2409:11A3
2357:10A7
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2347:10A2
2342:10A1
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1333:PMID
1325:ISSN
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1019:ISSN
970:PMID
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727:PMID
692:PMID
645:2u7c
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519:PMID
459:RHCG
455:RHCE
451:RHBG
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363:(in)
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234:RhCE
232:and
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218:RhBG
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200:and
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