314:
291:
188:
213:
565:
320:
219:
29:
1099:
who were also affected by breast cancer are positive for autoantibodies against this protein. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences have not been determined.
55:
1799:
Yamamoto R, Li X, Winter S, Francke U, Kilimann MW (February 1995). "Primary structure of human amphiphysin, the dominant autoantigen of paraneoplastic stiff-man syndrome, and mapping of its gene (AMPH) to chromosome 7p13-p14".
1962:"Amphiphysin II (SH3P9; BIN1), a member of the amphiphysin/Rvs family, is concentrated in the cortical cytomatrix of axon initial segments and nodes of ranvier in brain and around T tubules in skeletal muscle"
2581:
Zelhof AC, Bao H, Hardy RW, Razzaq A, Zhang B, Doe CQ (December 2001). "Drosophila
Amphiphysin is implicated in protein localization and membrane morphogenesis but not in synaptic vesicle endocytosis".
1146:
and is involved in the formation and stabilization of the T-tubule network. In other tissues amphiphysin is likely involved in other membrane bending and curvature stabilization events.
1831:"Autoimmunity in stiff-Man syndrome with breast cancer is targeted to the C-terminal region of human amphiphysin, a protein similar to the yeast proteins, Rvs167 and Rvs161"
327:
226:
2327:"Tandem arrangement of the clathrin and AP-2 binding domains in amphiphysin 1 and disruption of clathrin coat function by amphiphysin fragments comprising these sites"
2292:"The SH3 domains of endophilin and amphiphysin bind to the proline-rich region of synaptojanin 1 at distinct sites that display an unconventional binding specificity"
2789:"Amphiphysin is necessary for organization of the excitation-contraction coupling machinery of muscles, but not for synaptic vesicle endocytosis in Drosophila"
1712:"Characterization of Endophilin B1b, a brain-specific membrane-associated lysophosphatidic acid acyl transferase with properties distinct from endophilin A1"
2253:
Slepnev VI, Ochoa GC, Butler MH, Grabs D, De
Camilli P (August 1998). "Role of phosphorylation in regulation of the assembly of endocytic coat complexes".
798:
149:
779:
2656:
Takei K, Slepnev VI, Haucke V, De
Camilli P (May 1999). "Functional partnership between amphiphysin and dynamin in clathrin-mediated endocytosis".
1276:
2543:
Zhang B, Zelhof AC (July 2002). "Amphiphysins: raising the BAR for synaptic vesicle recycling and membrane dynamics. Bin-Amphiphysin-Rvsp".
2871:
1927:"The SH3 domain of amphiphysin binds the proline-rich domain of dynamin at a single site that defines a new SH3 binding consensus sequence"
1545:"The SH3 domain of amphiphysin binds the proline-rich domain of dynamin at a single site that defines a new SH3 binding consensus sequence"
1258:
313:
52:
2212:"Multiple amphiphysin II splice variants display differential clathrin binding: identification of two distinct clathrin-binding sites"
2843:
2837:
1021:
1014:
290:
2290:
Cestra G, Castagnoli L, Dente L, Minenkova O, Petrelli A, Migone N, Hoffmüller U, Schneider-Mergener J, Cesareni G (November 1999).
2612:
1346:
1245:
1224:
1123:
and adaptor binding domain and a C-terminal SH3 domain. In the brain, its primary function is thought to be the recruitment of
1241:
212:
187:
2849:
1220:
1296:"The synaptic vesicle-associated protein amphiphysin is the 128-kD autoantigen of Stiff-Man syndrome with breast cancer"
129:
2467:"Amphiphysin 1 binds the cyclin-dependent kinase (cdk) 5 regulatory subunit p35 and is phosphorylated by cdk5 and cdc2"
2395:
Onofri F, Giovedi S, Kao HT, Valtorta F, Bongiorno
Borbone L, De Camilli P, Greengard P, Benfenati F (September 2000).
1630:"Amphiphysin 1 binds the cyclin-dependent kinase (cdk) 5 regulatory subunit p35 and is phosphorylated by cdk5 and cdc2"
1155:
2746:"Amphiphysin is a component of clathrin coats formed during synaptic vesicle recycling at the lamprey giant synapse"
1294:
De
Camilli P, Thomas A, Cofiell R, Folli F, Lichte B, Piccolo G, Meinck HM, Austoni M, et al. (December 1993).
1095:
This gene encodes a protein associated with the cytoplasmic surface of synaptic vesicles. A subset of patients with
326:
225:
2167:
Floyd S, Butler MH, Cremona O, David C, Freyberg Z, Zhang X, Solimena M, Tokunaga A, et al. (January 1998).
319:
218:
2787:
Razzaq A, Robinson IM, McMahon HT, Skepper JN, Su Y, Zelhof AC, Jackson AP, Gay NJ, O'Kane CJ (November 2001).
1365:"Synaptojanin forms two separate complexes in the nerve terminal. Interactions with endophilin and amphiphysin"
843:
137:
1874:"A role of amphiphysin in synaptic vesicle endocytosis suggested by its binding to dynamin in nerve terminals"
2744:
Evergren E, Marcucci M, Tomilin N, Löw P, Slepnev V, Andersson F, Gad H, Brodin L, et al. (July 2004).
824:
2169:"Expression of amphiphysin I, an autoantigen of paraneoplastic neurological syndromes, in breast cancer"
1096:
2502:"Drosophila Amphiphysin is a post-synaptic protein required for normal locomotion but not endocytosis"
2706:
2262:
1885:
201:
2855:
1960:
Butler MH, David C, Ochoa GC, Freyberg Z, Daniell L, Grabs D, Cremona O, De
Camilli P (June 1997).
993:
942:
116:
2775:
2732:
2681:
2568:
2531:
2241:
2112:
2069:
1860:
1484:
1131:. There are 2 mammalian amphiphysins with similar overall structure. A ubiquitous splice form of
161:
997:
972:
968:
938:
917:
913:
2876:
2818:
2767:
2724:
2673:
2644:
2599:
2560:
2523:
2488:
2453:
2432:"The calcineurin-binding protein cain is a negative regulator of synaptic vesicle endocytosis"
2418:
2383:
2348:
2313:
2278:
2233:
2198:
2155:
2104:
2061:
2026:
1991:
1948:
1913:
1852:
1817:
1787:
1733:
1692:
1671:"The calcineurin-binding protein cain is a negative regulator of synaptic vesicle endocytosis"
1651:
1610:
1566:
1525:
1476:
1435:
1386:
1325:
1143:
109:
45:
2808:
2800:
2757:
2714:
2665:
2634:
2624:
2591:
2552:
2513:
2478:
2443:
2408:
2373:
2338:
2303:
2270:
2223:
2188:
2180:
2145:
2137:
2094:
2051:
2016:
1981:
1973:
1938:
1903:
1893:
1842:
1809:
1777:
1769:
1723:
1682:
1641:
1600:
1556:
1515:
1466:
1425:
1417:
1376:
1315:
1307:
1163:
564:
406:
337:
281:
236:
1347:"Entrez Gene: AMPH amphiphysin (Stiff-Man syndrome with breast cancer 128kDa autoantigen)"
381:
157:
2710:
2266:
2228:
2211:
1925:
Grabs D, Slepnev VI, Songyang Z, David C, Lynch M, Cantley LC, De
Camilli P (May 1997).
1889:
1543:
Grabs D, Slepnev VI, Songyang Z, David C, Lynch M, Cantley LC, De
Camilli P (May 1997).
2693:
Peter BJ, Kent HM, Mills IG, Vallis Y, Butler PJ, Evans PR, McMahon HT (January 2004).
2639:
2629:
2193:
2168:
1986:
1961:
1773:
1320:
1295:
2813:
2788:
2500:
Leventis PA, Chow BM, Stewart BA, Iyengar B, Campos AR, Boulianne GL (November 2001).
2099:
2082:
2056:
2039:
2005:"Identification and characterization of a nerve terminal-enriched amphiphysin isoform"
1782:
1757:
1471:
1454:
713:
708:
703:
698:
682:
677:
672:
667:
662:
657:
652:
647:
642:
637:
632:
627:
611:
606:
2865:
2762:
2745:
2556:
2518:
2501:
2150:
2125:
1908:
1873:
1847:
1830:
1430:
1405:
1112:
593:
2779:
2572:
2535:
2245:
2116:
2073:
1488:
2736:
2685:
2124:
Wigge P, Köhler K, Vallis Y, Doyle CA, Owen D, Hunt SP, McMahon HT (October 1997).
1404:
Wigge P, Köhler K, Vallis Y, Doyle CA, Owen D, Hunt SP, McMahon HT (October 1997).
399:
178:
141:
1864:
2274:
1504:"Dynamin is a minibrain kinase/dual specificity Yak1-related kinase 1A substrate"
165:
2613:"Drosophila amphiphysin functions during synaptic Fasciclin II membrane cycling"
1281:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1263:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1139:) that does not contain clathrin or adaptor interactions is highly expressed in
1128:
1878:
Proceedings of the National Academy of Sciences of the United States of America
482:
2465:
Floyd SR, Porro EB, Slepnev VI, Ochoa GC, Tsai LH, De Camilli P (March 2001).
2040:"Clathrin interacts specifically with amphiphysin and is displaced by dynamin"
1628:
Floyd SR, Porro EB, Slepnev VI, Ochoa GC, Tsai LH, De Camilli P (March 2001).
1455:"Clathrin interacts specifically with amphiphysin and is displaced by dynamin"
1116:
298:
195:
145:
2695:"BAR domains as sensors of membrane curvature: the amphiphysin BAR structure"
2308:
2291:
2021:
2004:
1943:
1926:
1561:
1544:
1381:
1364:
2719:
2694:
2595:
743:
542:
420:
365:
352:
264:
251:
153:
2822:
2771:
2728:
2677:
2648:
2603:
2564:
2527:
2492:
2483:
2466:
2457:
2448:
2431:
2422:
2413:
2396:
2387:
2378:
2361:
2352:
2343:
2326:
2317:
2126:"Amphiphysin heterodimers: potential role in clathrin-mediated endocytosis"
1977:
1737:
1728:
1711:
1696:
1687:
1670:
1655:
1646:
1629:
1614:
1605:
1588:
1529:
1520:
1503:
1406:"Amphiphysin heterodimers: potential role in clathrin-mediated endocytosis"
1311:
2282:
2237:
2202:
2159:
2141:
2108:
2065:
2030:
1995:
1952:
1917:
1898:
1856:
1821:
1813:
1791:
1710:
Modregger J, Schmidt AA, Ritter B, Huttner WB, Plomann M (February 2003).
1570:
1480:
1439:
1421:
1390:
1329:
1061:
1056:
28:
1120:
1045:
888:
869:
2804:
2360:
Lee C, Kim SR, Chung JK, Frohman MA, Kilimann MW, Rhee SG (June 2000).
2184:
1587:
Lee C, Kim SR, Chung JK, Frohman MA, Kilimann MW, Rhee SG (June 2000).
1124:
1104:
1077:
855:
810:
86:
82:
78:
74:
1179:
1175:
1167:
1140:
1029:
765:
2397:"Specificity of the binding of synapsin I to Src homology 3 domains"
2083:"SH3 domain-dependent interactions of endophilin with amphiphysin"
1196:
1191:
1108:
2669:
728:
724:
2430:
Lai MM, Luo HR, Burnett PE, Hong JJ, Snyder SH (November 2000).
1758:"Amphiphysin, a novel protein associated with synaptic vesicles"
1669:
Lai MM, Luo HR, Burnett PE, Hong JJ, Snyder SH (November 2000).
1171:
1159:
1136:
1084:
133:
2081:
Micheva KD, Ramjaun AR, Kay BK, McPherson PS (September 1997).
2003:
Ramjaun AR, Micheva KD, Bouchelet I, McPherson PS (June 1997).
1872:
David C, McPherson PS, Mundigl O, de Camilli P (January 1996).
573:
2325:
Slepnev VI, Ochoa GC, Butler MH, De Camilli P (June 2000).
1502:
Chen-Hwang MC, Chen HR, Elzinga M, Hwang YW (May 2002).
389:
2838:
Bringing your curves to the bar, amphiphysin home page
1756:
Lichte B, Veh RW, Meyer HE, Kilimann MW (July 1992).
554:
986:
961:
931:
906:
525:
dentate gyrus of hippocampal formation granule cell
1237:
1235:
1233:
1216:
1214:
1212:
1829:David C, Solimena M, De Camilli P (August 1994).
1363:Micheva KD, Kay BK, McPherson PS (October 1997).
336:
235:
2611:Mathew D, Popescu A, Budnik V (November 2003).
2362:"Inhibition of phospholipase D by amphiphysins"
1589:"Inhibition of phospholipase D by amphiphysins"
1582:
1580:
16:Protein-coding gene in the species Homo sapiens
1242:GRCm38: Ensembl release 89: ENSMUSG00000021314
1358:
1356:
8:
2038:McMahon HT, Wigge P, Smith C (August 1997).
1453:McMahon HT, Wigge P, Smith C (August 1997).
1221:GRCh38: Ensembl release 89: ENSG00000078053
739:
589:
377:
276:
173:
63:
2812:
2761:
2718:
2638:
2628:
2517:
2482:
2447:
2412:
2377:
2342:
2307:
2227:
2192:
2149:
2098:
2055:
2020:
1985:
1942:
1907:
1897:
1846:
1781:
1727:
1686:
1645:
1604:
1560:
1519:
1470:
1429:
1380:
1319:
1341:
1339:
1208:
2210:Ramjaun AR, McPherson PS (June 1998).
18:
341:
302:
297:
240:
199:
194:
7:
1300:The Journal of Experimental Medicine
2471:The Journal of Biological Chemistry
2436:The Journal of Biological Chemistry
2401:The Journal of Biological Chemistry
2366:The Journal of Biological Chemistry
2331:The Journal of Biological Chemistry
2296:The Journal of Biological Chemistry
2229:10.1046/j.1471-4159.1998.70062369.x
2009:The Journal of Biological Chemistry
1931:The Journal of Biological Chemistry
1716:The Journal of Biological Chemistry
1675:The Journal of Biological Chemistry
1634:The Journal of Biological Chemistry
1593:The Journal of Biological Chemistry
1549:The Journal of Biological Chemistry
1508:The Journal of Biological Chemistry
1369:The Journal of Biological Chemistry
2630:10.1523/JNEUROSCI.23-33-10710.2003
1774:10.1002/j.1460-2075.1992.tb05317.x
983:
958:
928:
903:
879:
860:
834:
815:
789:
770:
559:
477:
415:
394:
14:
1080:that in humans is encoded by the
2763:10.1111/j.1398-9219.2004.00198.x
2557:10.1034/j.1600-0854.2002.30702.x
2519:10.1034/j.1600-0854.2001.21113.x
1103:Amphiphysin is a brain-enriched
563:
325:
318:
312:
289:
224:
217:
211:
186:
27:
1154:Amphiphysin has been shown to
1127:to sites of clathrin-mediated
1111:interaction, dimerisation and
704:chemical synaptic transmission
574:More reference expression data
543:More reference expression data
1:
2130:Molecular Biology of the Cell
2100:10.1016/S0014-5793(97)01016-8
2057:10.1016/S0014-5793(97)00928-9
1472:10.1016/S0014-5793(97)00928-9
1410:Molecular Biology of the Cell
310:
209:
2275:10.1126/science.281.5378.821
1848:10.1016/0014-5793(94)00826-4
714:synaptic vesicle endocytosis
2872:Genes on human chromosome 7
2617:The Journal of Neuroscience
1966:The Journal of Cell Biology
443:paraflocculus of cerebellum
2893:
2854:gene details page in the
2216:Journal of Neurochemistry
1277:"Mouse PubMed Reference:"
1259:"Human PubMed Reference:"
1060:
1055:
1051:
1044:
1028:
1009:
990:
965:
954:
935:
910:
899:
886:
882:
867:
863:
854:
841:
837:
822:
818:
809:
796:
792:
777:
773:
764:
749:
742:
738:
722:
648:synaptic vesicle membrane
592:
588:
571:
562:
553:
540:
489:
480:
427:
418:
388:
380:
376:
359:
346:
309:
288:
279:
275:
258:
245:
208:
185:
176:
172:
127:
124:
114:
107:
102:
71:
66:
49:
44:
39:
35:
26:
21:
2309:10.1074/jbc.274.45.32001
2022:10.1074/jbc.272.26.16700
1944:10.1074/jbc.272.20.13419
1802:Human Molecular Genetics
1562:10.1074/jbc.272.20.13419
1382:10.1074/jbc.272.43.27239
1022:Chr 13: 19.13 – 19.34 Mb
2793:Genes & Development
2720:10.1126/science.1092586
2596:10.1242/dev.128.24.5005
1015:Chr 7: 38.38 – 38.63 Mb
2484:10.1074/jbc.M008932200
2449:10.1074/jbc.C000429200
2414:10.1074/jbc.M006018200
2379:10.1074/jbc.M001695200
2344:10.1074/jbc.M910430199
1978:10.1083/jcb.137.6.1355
1729:10.1074/jbc.M208568200
1688:10.1074/jbc.C000429200
1647:10.1074/jbc.M008932200
1606:10.1074/jbc.M001695200
1521:10.1074/jbc.M111101200
1312:10.1084/jem.178.6.2219
467:superior frontal gyrus
2142:10.1091/mbc.8.10.2003
1899:10.1073/pnas.93.1.331
1422:10.1091/mbc.8.10.2003
1097:stiff person syndrome
709:membrane organization
673:leading edge membrane
431:middle temporal gyrus
343:13 A2|13 6.89 cM
304:Chromosome 13 (mouse)
2848:genome location and
612:phospholipid binding
459:orbitofrontal cortex
202:Chromosome 7 (human)
120:, AMPH1, amphiphysin
67:List of PDB id codes
40:Available structures
2856:UCSC Genome Browser
2711:2004Sci...303..495P
2658:Nature Cell Biology
2267:1998Sci...281..821S
1890:1996PNAS...93..331D
1814:10.1093/hmg/4.2.265
1107:with an N-terminal
663:cytoplasmic vesicle
2805:10.1101/gad.207801
2185:10.1007/BF03401727
2173:Molecular Medicine
844:ENSMUSG00000021314
692:Biological process
628:actin cytoskeleton
621:Cellular component
600:Molecular function
513:hippocampus proper
1514:(20): 17597–604.
1071:
1070:
1067:
1066:
1040:
1039:
1005:
1004:
980:
979:
950:
949:
925:
924:
895:
894:
876:
875:
850:
849:
831:
830:
805:
804:
786:
785:
734:
733:
584:
583:
580:
579:
549:
548:
536:
535:
474:
473:
455:cerebellar vermis
372:
371:
271:
270:
98:
97:
94:
93:
50:Ortholog search:
2884:
2826:
2816:
2783:
2765:
2740:
2722:
2689:
2652:
2642:
2632:
2607:
2576:
2539:
2521:
2496:
2486:
2461:
2451:
2442:(44): 34017–20.
2426:
2416:
2407:(38): 29857–67.
2391:
2381:
2356:
2346:
2321:
2311:
2286:
2249:
2231:
2206:
2196:
2163:
2153:
2120:
2102:
2077:
2059:
2034:
2024:
1999:
1989:
1956:
1946:
1937:(20): 13419–25.
1921:
1911:
1901:
1868:
1850:
1825:
1795:
1785:
1762:The EMBO Journal
1742:
1741:
1731:
1707:
1701:
1700:
1690:
1681:(44): 34017–20.
1666:
1660:
1659:
1649:
1625:
1619:
1618:
1608:
1584:
1575:
1574:
1564:
1555:(20): 13419–25.
1540:
1534:
1533:
1523:
1499:
1493:
1492:
1474:
1450:
1444:
1443:
1433:
1401:
1395:
1394:
1384:
1375:(43): 27239–45.
1360:
1351:
1350:
1343:
1334:
1333:
1323:
1291:
1285:
1284:
1273:
1267:
1266:
1255:
1249:
1239:
1228:
1218:
1164:Phospholipase D1
1053:
1052:
1024:
1017:
1000:
984:
975:
959:
955:RefSeq (protein)
945:
929:
920:
904:
880:
861:
835:
816:
790:
771:
740:
668:synaptic vesicle
590:
576:
567:
560:
545:
485:
483:Top expressed in
478:
463:Brodmann area 46
451:Brodmann area 10
435:endothelial cell
423:
421:Top expressed in
416:
395:
378:
368:
355:
344:
329:
322:
316:
305:
293:
277:
267:
254:
243:
228:
221:
215:
204:
190:
174:
168:
166:AMPH - orthologs
119:
112:
89:
64:
58:
37:
36:
31:
19:
2892:
2891:
2887:
2886:
2885:
2883:
2882:
2881:
2862:
2861:
2834:
2829:
2799:(22): 2967–79.
2786:
2743:
2705:(5657): 495–9.
2692:
2655:
2623:(33): 10710–6.
2610:
2590:(24): 5005–15.
2580:
2542:
2499:
2477:(11): 8104–10.
2464:
2429:
2394:
2372:(25): 18751–8.
2359:
2337:(23): 17583–9.
2324:
2302:(45): 32001–7.
2289:
2261:(5378): 821–4.
2252:
2209:
2166:
2136:(10): 2003–15.
2123:
2080:
2037:
2015:(26): 16700–6.
2002:
1959:
1924:
1871:
1828:
1798:
1755:
1751:
1749:Further reading
1746:
1745:
1709:
1708:
1704:
1668:
1667:
1663:
1640:(11): 8104–10.
1627:
1626:
1622:
1599:(25): 18751–8.
1586:
1585:
1578:
1542:
1541:
1537:
1501:
1500:
1496:
1452:
1451:
1447:
1416:(10): 2003–15.
1403:
1402:
1398:
1362:
1361:
1354:
1345:
1344:
1337:
1293:
1292:
1288:
1275:
1274:
1270:
1257:
1256:
1252:
1240:
1231:
1219:
1210:
1205:
1188:
1152:
1093:
1062:View/Edit Mouse
1057:View/Edit Human
1020:
1013:
1010:Location (UCSC)
996:
992:
971:
967:
941:
937:
916:
912:
825:ENSG00000078053
718:
687:
683:plasma membrane
616:
607:protein binding
572:
541:
532:
527:
523:
519:
515:
511:
507:
505:piriform cortex
503:
499:
495:
481:
470:
465:
461:
457:
453:
449:
445:
441:
437:
433:
419:
363:
350:
342:
332:
331:
330:
323:
303:
280:Gene location (
262:
249:
241:
231:
230:
229:
222:
200:
177:Gene location (
128:
115:
108:
73:
51:
17:
12:
11:
5:
2890:
2888:
2880:
2879:
2874:
2864:
2863:
2860:
2859:
2840:
2833:
2832:External links
2830:
2828:
2827:
2784:
2741:
2690:
2653:
2608:
2578:
2540:
2512:(11): 839–50.
2497:
2462:
2427:
2392:
2357:
2322:
2287:
2250:
2222:(6): 2369–76.
2207:
2164:
2121:
2078:
2035:
2000:
1972:(6): 1355–67.
1957:
1922:
1869:
1826:
1796:
1768:(7): 2521–30.
1752:
1750:
1747:
1744:
1743:
1702:
1661:
1620:
1576:
1535:
1494:
1445:
1396:
1352:
1335:
1306:(6): 2219–23.
1286:
1268:
1250:
1229:
1207:
1206:
1204:
1201:
1200:
1199:
1194:
1187:
1184:
1151:
1148:
1092:
1089:
1069:
1068:
1065:
1064:
1059:
1049:
1048:
1042:
1041:
1038:
1037:
1035:
1033:
1026:
1025:
1018:
1011:
1007:
1006:
1003:
1002:
988:
987:
981:
978:
977:
963:
962:
956:
952:
951:
948:
947:
933:
932:
926:
923:
922:
908:
907:
901:
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893:
892:
884:
883:
877:
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873:
865:
864:
858:
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851:
848:
847:
839:
838:
832:
829:
828:
820:
819:
813:
807:
806:
803:
802:
794:
793:
787:
784:
783:
775:
774:
768:
762:
761:
756:
751:
747:
746:
736:
735:
732:
731:
720:
719:
717:
716:
711:
706:
701:
695:
693:
689:
688:
686:
685:
680:
675:
670:
665:
660:
655:
650:
645:
640:
635:
630:
624:
622:
618:
617:
615:
614:
609:
603:
601:
597:
596:
586:
585:
582:
581:
578:
577:
569:
568:
557:
551:
550:
547:
546:
538:
537:
534:
533:
531:
530:
526:
522:
518:
517:pontine nuclei
514:
510:
506:
502:
498:
494:
490:
487:
486:
475:
472:
471:
469:
468:
464:
460:
456:
452:
448:
444:
440:
436:
432:
428:
425:
424:
412:
411:
403:
392:
386:
385:
382:RNA expression
374:
373:
370:
369:
361:
357:
356:
348:
345:
340:
334:
333:
324:
317:
311:
307:
306:
301:
295:
294:
286:
285:
273:
272:
269:
268:
260:
256:
255:
247:
244:
239:
233:
232:
223:
216:
210:
206:
205:
198:
192:
191:
183:
182:
170:
169:
126:
122:
121:
113:
105:
104:
100:
99:
96:
95:
92:
91:
69:
68:
60:
59:
48:
42:
41:
33:
32:
24:
23:
15:
13:
10:
9:
6:
4:
3:
2:
2889:
2878:
2875:
2873:
2870:
2869:
2867:
2857:
2853:
2852:
2847:
2846:
2841:
2839:
2836:
2835:
2831:
2824:
2820:
2815:
2810:
2806:
2802:
2798:
2794:
2790:
2785:
2781:
2777:
2773:
2769:
2764:
2759:
2756:(7): 514–28.
2755:
2751:
2747:
2742:
2738:
2734:
2730:
2726:
2721:
2716:
2712:
2708:
2704:
2700:
2696:
2691:
2687:
2683:
2679:
2675:
2671:
2667:
2663:
2659:
2654:
2650:
2646:
2641:
2636:
2631:
2626:
2622:
2618:
2614:
2609:
2605:
2601:
2597:
2593:
2589:
2585:
2579:
2574:
2570:
2566:
2562:
2558:
2554:
2551:(7): 452–60.
2550:
2546:
2541:
2537:
2533:
2529:
2525:
2520:
2515:
2511:
2507:
2503:
2498:
2494:
2490:
2485:
2480:
2476:
2472:
2468:
2463:
2459:
2455:
2450:
2445:
2441:
2437:
2433:
2428:
2424:
2420:
2415:
2410:
2406:
2402:
2398:
2393:
2389:
2385:
2380:
2375:
2371:
2367:
2363:
2358:
2354:
2350:
2345:
2340:
2336:
2332:
2328:
2323:
2319:
2315:
2310:
2305:
2301:
2297:
2293:
2288:
2284:
2280:
2276:
2272:
2268:
2264:
2260:
2256:
2251:
2247:
2243:
2239:
2235:
2230:
2225:
2221:
2217:
2213:
2208:
2204:
2200:
2195:
2190:
2186:
2182:
2178:
2174:
2170:
2165:
2161:
2157:
2152:
2147:
2143:
2139:
2135:
2131:
2127:
2122:
2118:
2114:
2110:
2106:
2101:
2096:
2093:(2): 308–12.
2092:
2088:
2084:
2079:
2075:
2071:
2067:
2063:
2058:
2053:
2050:(2): 319–22.
2049:
2045:
2041:
2036:
2032:
2028:
2023:
2018:
2014:
2010:
2006:
2001:
1997:
1993:
1988:
1983:
1979:
1975:
1971:
1967:
1963:
1958:
1954:
1950:
1945:
1940:
1936:
1932:
1928:
1923:
1919:
1915:
1910:
1905:
1900:
1895:
1891:
1887:
1883:
1879:
1875:
1870:
1866:
1862:
1858:
1854:
1849:
1844:
1840:
1836:
1832:
1827:
1823:
1819:
1815:
1811:
1807:
1803:
1797:
1793:
1789:
1784:
1779:
1775:
1771:
1767:
1763:
1759:
1754:
1753:
1748:
1739:
1735:
1730:
1725:
1722:(6): 4160–7.
1721:
1717:
1713:
1706:
1703:
1698:
1694:
1689:
1684:
1680:
1676:
1672:
1665:
1662:
1657:
1653:
1648:
1643:
1639:
1635:
1631:
1624:
1621:
1616:
1612:
1607:
1602:
1598:
1594:
1590:
1583:
1581:
1577:
1572:
1568:
1563:
1558:
1554:
1550:
1546:
1539:
1536:
1531:
1527:
1522:
1517:
1513:
1509:
1505:
1498:
1495:
1490:
1486:
1482:
1478:
1473:
1468:
1465:(2): 319–22.
1464:
1460:
1456:
1449:
1446:
1441:
1437:
1432:
1427:
1423:
1419:
1415:
1411:
1407:
1400:
1397:
1392:
1388:
1383:
1378:
1374:
1370:
1366:
1359:
1357:
1353:
1348:
1342:
1340:
1336:
1331:
1327:
1322:
1317:
1313:
1309:
1305:
1301:
1297:
1290:
1287:
1282:
1278:
1272:
1269:
1264:
1260:
1254:
1251:
1247:
1243:
1238:
1236:
1234:
1230:
1226:
1222:
1217:
1215:
1213:
1209:
1202:
1198:
1195:
1193:
1190:
1189:
1185:
1183:
1181:
1177:
1173:
1169:
1165:
1161:
1157:
1149:
1147:
1145:
1142:
1138:
1134:
1133:amphiphysin-2
1130:
1126:
1122:
1118:
1114:
1110:
1106:
1101:
1098:
1090:
1088:
1086:
1083:
1079:
1075:
1063:
1058:
1054:
1050:
1047:
1043:
1036:
1034:
1031:
1027:
1023:
1019:
1016:
1012:
1008:
1001:
999:
995:
989:
985:
982:
976:
974:
970:
964:
960:
957:
953:
946:
944:
940:
934:
930:
927:
921:
919:
915:
909:
905:
902:
900:RefSeq (mRNA)
898:
891:
890:
885:
881:
878:
872:
871:
866:
862:
859:
857:
853:
846:
845:
840:
836:
833:
827:
826:
821:
817:
814:
812:
808:
801:
800:
795:
791:
788:
782:
781:
776:
772:
769:
767:
763:
760:
757:
755:
752:
748:
745:
741:
737:
730:
726:
721:
715:
712:
710:
707:
705:
702:
700:
697:
696:
694:
691:
690:
684:
681:
679:
676:
674:
671:
669:
666:
664:
661:
659:
656:
654:
651:
649:
646:
644:
641:
639:
638:cell junction
636:
634:
631:
629:
626:
625:
623:
620:
619:
613:
610:
608:
605:
604:
602:
599:
598:
595:
594:Gene ontology
591:
587:
575:
570:
566:
561:
558:
556:
552:
544:
539:
528:
524:
521:dentate gyrus
520:
516:
512:
509:barrel cortex
508:
504:
500:
496:
492:
491:
488:
484:
479:
476:
466:
462:
458:
454:
450:
446:
442:
438:
434:
430:
429:
426:
422:
417:
414:
413:
410:
408:
404:
402:
401:
397:
396:
393:
391:
387:
383:
379:
375:
367:
362:
358:
354:
349:
339:
335:
328:
321:
315:
308:
300:
296:
292:
287:
283:
278:
274:
266:
261:
257:
253:
248:
238:
234:
227:
220:
214:
207:
203:
197:
193:
189:
184:
180:
175:
171:
167:
163:
159:
155:
151:
147:
143:
139:
135:
131:
123:
118:
111:
106:
101:
90:
88:
84:
80:
76:
70:
65:
62:
61:
57:
54:
47:
43:
38:
34:
30:
25:
20:
2850:
2844:
2796:
2792:
2753:
2749:
2702:
2698:
2670:10.1038/9004
2661:
2657:
2620:
2616:
2587:
2583:
2548:
2544:
2509:
2505:
2474:
2470:
2439:
2435:
2404:
2400:
2369:
2365:
2334:
2330:
2299:
2295:
2258:
2254:
2219:
2215:
2179:(1): 29–39.
2176:
2172:
2133:
2129:
2090:
2087:FEBS Letters
2086:
2047:
2044:FEBS Letters
2043:
2012:
2008:
1969:
1965:
1934:
1930:
1884:(1): 331–5.
1881:
1877:
1838:
1835:FEBS Letters
1834:
1808:(2): 265–8.
1805:
1801:
1765:
1761:
1719:
1715:
1705:
1678:
1674:
1664:
1637:
1633:
1623:
1596:
1592:
1552:
1548:
1538:
1511:
1507:
1497:
1462:
1459:FEBS Letters
1458:
1448:
1413:
1409:
1399:
1372:
1368:
1303:
1299:
1289:
1280:
1271:
1262:
1253:
1153:
1150:Interactions
1132:
1102:
1094:
1081:
1073:
1072:
994:NP_001276475
991:
966:
943:NM_001289546
936:
911:
887:
868:
842:
823:
797:
778:
758:
753:
653:cytoskeleton
529:otic placode
501:otic vesicle
439:frontal pole
405:
398:
125:External IDs
72:
2664:(1): 33–9.
2584:Development
1841:(1): 73–9.
1129:endocytosis
1119:, a middle
1074:Amphiphysin
699:endocytosis
364:19,335,091
351:19,132,375
263:38,631,420
250:38,383,704
103:Identifiers
2866:Categories
1248:, May 2017
1227:, May 2017
1203:References
1117:BAR domain
409:(ortholog)
146:HomoloGene
998:NP_778172
973:NP_647477
969:NP_001626
939:NM_175007
918:NM_139316
914:NM_001635
744:Orthologs
633:cytoplasm
154:GeneCards
2877:Proteins
2823:11711432
2780:33206924
2772:15180828
2729:14645856
2678:10559861
2649:14627656
2604:11748137
2573:37496168
2565:12047553
2536:42486176
2528:11733051
2493:11113134
2458:10931822
2423:10899172
2388:10764771
2353:10748223
2318:10542231
2246:21910795
2117:21328416
2074:42520828
1738:12456676
1697:10931822
1656:11113134
1615:10764771
1530:11877424
1489:42520828
1244:–
1223:–
1186:See also
1156:interact
1121:clathrin
1115:bending
1113:membrane
1091:Function
1046:Wikidata
723:Sources:
658:membrane
497:amygdala
2750:Traffic
2737:6104655
2707:Bibcode
2699:Science
2686:6384633
2640:6740931
2577:Review.
2545:Traffic
2506:Traffic
2283:9694653
2263:Bibcode
2255:Science
2238:9603201
2203:9513187
2194:2230265
2160:9348539
2109:9315708
2066:9280305
2031:9195986
1996:9182667
1987:2132527
1953:9148966
1918:8552632
1886:Bibcode
1857:8076697
1822:7757077
1792:1628617
1571:9148966
1481:9280305
1440:9348539
1391:9341169
1330:8245793
1321:2191289
1246:Ensembl
1225:Ensembl
1125:dynamin
1105:protein
1078:protein
856:UniProt
811:Ensembl
750:Species
729:QuickGO
678:cytosol
643:synapse
493:saccule
384:pattern
110:Aliases
2842:Human
2821:
2814:312829
2811:
2778:
2770:
2735:
2727:
2684:
2676:
2647:
2637:
2602:
2571:
2563:
2534:
2526:
2491:
2456:
2421:
2386:
2351:
2316:
2281:
2244:
2236:
2201:
2191:
2158:
2148:
2115:
2107:
2072:
2064:
2029:
1994:
1984:
1951:
1916:
1906:
1865:133561
1863:
1855:
1820:
1790:
1783:556727
1780:
1736:
1695:
1654:
1613:
1569:
1528:
1487:
1479:
1438:
1428:
1389:
1328:
1318:
1180:SH3GL2
1176:CABIN1
1168:CDK5R1
1144:tissue
1141:muscle
1032:search
1030:PubMed
889:Q7TQF7
870:P49418
799:218038
766:Entrez
555:BioGPS
242:7p14.1
150:121585
142:103574
134:600418
2776:S2CID
2733:S2CID
2682:S2CID
2569:S2CID
2532:S2CID
2242:S2CID
2151:25662
2113:S2CID
2070:S2CID
1909:40232
1861:S2CID
1485:S2CID
1431:25662
1197:Epsin
1192:AP180
1158:with
1109:lipid
1076:is a
759:Mouse
754:Human
725:Amigo
407:Mouse
400:Human
347:Start
282:Mouse
246:Start
179:Human
2851:AMPH
2845:AMPH
2819:PMID
2768:PMID
2725:PMID
2674:PMID
2645:PMID
2600:PMID
2561:PMID
2524:PMID
2489:PMID
2454:PMID
2419:PMID
2384:PMID
2349:PMID
2314:PMID
2279:PMID
2234:PMID
2199:PMID
2156:PMID
2105:PMID
2062:PMID
2027:PMID
1992:PMID
1949:PMID
1914:PMID
1853:PMID
1818:PMID
1788:PMID
1734:PMID
1693:PMID
1652:PMID
1611:PMID
1567:PMID
1526:PMID
1477:PMID
1436:PMID
1387:PMID
1326:PMID
1178:and
1172:PLD2
1160:DNM1
1137:BIN1
1085:gene
1082:AMPH
447:pons
390:Bgee
338:Band
299:Chr.
237:Band
196:Chr.
158:AMPH
130:OMIM
117:AMPH
87:4ATM
83:3SOG
79:1UTC
75:1KY7
56:RCSB
53:PDBe
22:AMPH
2809:PMC
2801:doi
2758:doi
2715:doi
2703:303
2666:doi
2635:PMC
2625:doi
2592:doi
2588:128
2553:doi
2514:doi
2479:doi
2475:276
2444:doi
2440:275
2409:doi
2405:275
2374:doi
2370:275
2339:doi
2335:275
2304:doi
2300:274
2271:doi
2259:281
2224:doi
2189:PMC
2181:doi
2146:PMC
2138:doi
2095:doi
2091:414
2052:doi
2048:413
2017:doi
2013:272
1982:PMC
1974:doi
1970:137
1939:doi
1935:272
1904:PMC
1894:doi
1843:doi
1839:351
1810:doi
1778:PMC
1770:doi
1724:doi
1720:278
1683:doi
1679:275
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