Knowledge (XXG)

Ampoule

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351:. This standard dictates three standardized forms: B, cut/straight-form; C, open-funnel; and D, sealed. (The "A" form is no longer used in the pharmaceutical industry and is not included in the updated version.) ISO 9187-1:2010 addresses what materials should be used in their manufacture, what the dimensions should be, what capacities they should have, how they should perform, and how they should be packaged. Characteristics such as 128: 2417: 340: 120: 39: 316: 331:, such as intravenously under hospital care, at greater risk of receiving glass particulates when medication is aspirated. A 2016 study of 180 ampoules found 19,473 glass particles in aspirated fluids, with filtering only reducing the mean by 114 to 89 particles per ampoule. Glass particle contamination of an ampule occurred with all intravenous injection methods. 307:, various silver salts and so on can be packaged in ampoules of smoked glass, glass with chemicals added in manufacturing that filter out ultraviolet and other types of light, or be made with an opaque top and bottom (usually painted with opaque paint) and the rest of the ampoule wrapped in thick paper. 370:
around their necks that are meant to identify the substance inside the ampoule. The rings are machine-readable and allow for accurate handling of the substance for the purposes of storage, labeling, and secondary packaging. Color coding of modern ampoules is done during the manufacturing process. A
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Ampoules are opened by scoring the neck and snapping the top off. In the "one point cut" (OPC) ampoules a dot above the neck identifies the correct thumb placement that aligns the thumb with a pre-made micro-score in the ampoule. If properly done, this last operation creates a clean break without
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The filling and sealing of ampoules may be done by automated machinery on an industrial scale, or by hand in small-scale industries and laboratory. Ampoule-filling machines can be categorized in three categories called automatic machine, semi automatic machine, and manual (hand-operated) machines.
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Glass ampoules are more expensive than bottles and other simple containers, but there are many situations where their superior imperviousness to gases and liquids and all-glass interior surface are worth the extra cost. Examples of chemicals sold in ampoules are
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may be used for sealing under inert atmospheres. There is procedure of purging nitrogen before and after filling liquid into ampoules in order to remove atmospheric air available inside the ampoules.
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less than half a week) and special thick-walled quartz and fluorite ampoules under high pressure containing fluorine and chlorine liquefied by the high pressure.
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Ampoules can be pressurised, have air evacuated from them, and have the air in the ampoule replaced with other gasses, often inert ones. The radio-pharmaceutical
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often is packaged in glass ampoules and specially-shaped glass ampoules have long been used for samples of gaseous elements, such as all of the
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by melting the thin top with an open flame, and usually opened by snapping off the neck. The space above the chemical may be filled with an
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Historically, ampoules were used to contain a small sample of a person's blood after death, which was entombed alongside them in many
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Swift, Robert; Schaut, Robert; Flynn, Carol Rea; Asselta, Roger (19 July 2019), Nema, Sandeep; Ludwig, John D. (eds.),
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the metal by rapidly forming a layer of a new inert compound on the metal surface reliably and predictably or at all.
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which is used to contain and preserve a sample, usually a solid or liquid. Ampoules are usually made of glass.
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Blank ampoules can be purchased from scientific glass supply houses and sealed with a small gas torch. A
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Ecology and Behaviour of Free-Ranging Animals Studied by Advanced Data-Logging and Tracking Techniques
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Wassmer, Thomas; Murray, Dennis; Boutin, Stan; Fahlman, Andreas; Jensen, Frants Havmand, eds. (2020).
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any extra glass shards or slivers, but the liquid or solution may be filtered for greater assurance.
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Veal, N. (1 June 1965). "The handling and dispensing of xenon-133: Gas shipments for clinical use".
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were given this burial treatment, though it is suspected to have been a widely practiced tradition.
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An ampere cutter that cuts the neck to open the ampoule. Not required for "one point cut ampoule"
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before sealing. The walls of glass ampoules are usually sufficiently strong to be brought into a
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Glass-particle contamination is of ongoing concern, with patients who receive medication
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The production and packaging of ampoules are largely standardized by ISO 9187-1:2010
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Containment Technology: Progress in the Pharmaceutical and Food Processing Industry.
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ampoules have been developed, based on the concept of the Teflon jug for high-
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and chemicals that must be protected from air and contaminants. They are
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Viaggio nelle catacombe di Roma di un membro dell'Accademia di Cortona
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Injection equipment for medical use — Part 1: Ampoules for injectables
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Modern glass ampoules are produced industrially from short lengths of
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Joo, Ga Eul; Sohng, Kyeong-Yae; Park, Michael Yong (6 January 2016).
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machine applies colored rings on the ampoule between the two ovens.
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Photosensitive chemicals like many 14-dihydromorphinone opioids like
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An ampoule allegedly dating back to the year 305 and filled with the
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A large ampoule containing 1.4 kg (3.1 lb) of high-purity
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International Organization for Standardization (October 2010).
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monarchs. The oil was allegedly passed down from the time of
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Ampoules are common practice as containers of low-frequency
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The International Journal of Applied Radiation and Isotopes
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Pages displaying wikidata descriptions as a fallback
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Diagram of an ampoule showing color-coded neck rings
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It was originally believed that only 97:tetrakis(triphenylphosphine)palladium(0) 408: 362:Ampoules often have colored rings of 174:, has been kept for centuries in the 7: 1318:Flexible intermediate bulk container 667: 665: 620: 618: 248:techniques are usually employed for 359:are specified for all three forms. 2302:Vertical form fill sealing machine 189:Another well-known ampoule is the 25: 2272:Rotary wheel blow molding systems 1120:Purdue Improved Crop Storage bags 541:10.1046/j.1365-2044.2003.296812.x 2416: 2415: 2242:Mechanical brake stretch wrapper 123:A collection of ancient ampoules 1976:Electronic article surveillance 1830:Shock and vibration data logger 1675:Linear low-density polyethylene 2081:Radio-frequency identification 222:Cathedral of Notre-Dame, Reims 95:, air-sensitive reagents like 27:Hermetically-sealed glass vial 1: 2192:Extended core stretch wrapper 1145:Single-serve coffee container 426:, Milano, G. Silvestri, 1835. 355:, hydrolytic resistance, and 109:trifluoromethanesulfonic acid 1348:Insulated shipping container 469:10.1016/0020-708X(65)90023-2 111:, and analytical standards. 2448:Medicine storage containers 2237:Material-handling equipment 2121:Verification and validation 1353:Intermediate bulk container 1135:Self-heating food packaging 2469: 1880:Time temperature indicator 436:Thurston, Herbert (1910). 2413: 2335:Environmental engineering 2297:Turntable stretch wrapper 2227:Lineshaft roller conveyor 2217:Injection molding machine 1155:Toothpaste pump dispenser 1015:Disposable food packaging 857:Child-resistant packaging 763:10.3389/978-2-88963-792-8 590:10.1186/s40064-015-1632-0 240:, shaped by heating with 2222:Label printer applicator 2091:Shearing (manufacturing) 1690:Low-density polyethylene 1110:Pharmaceutical packaging 1080:Low plastic water bottle 970:Alternative wine closure 639:10.1201/9780429201400-25 84:without any difficulty. 2453:Single-serve containers 2252:Orbital stretch wrapper 1875:Temperature data logger 1795:Pressure-sensitive tape 1655:Humidity indicator card 1183:Aerosol spray dispenser 794:Springer, Berlin 2013, 226:coronation of Charles X 1971:Die forming (plastics) 1680:Liquid packaging board 1383:Multilayered packaging 1115:Plastic milk container 1095:Optical disc packaging 631:Parenteral Medications 344: 320: 144: 124: 46: 35: 2400:Sustainable packaging 2350:Life-cycle assessment 2330:Closed-loop box reuse 2277:Seed-counting machine 1610:Corrugated fiberboard 1560:Biodegradable plastic 1283:Corrugated box design 937:Sustainable packaging 927:Shelf-ready packaging 902:Packaging engineering 696:"Let's make ampoules" 442:Catholic Encyclopedia 342: 318: 224:. It was used at the 130: 122: 61:) is a small sealed 41: 33: 2370:PET bottle recycling 2232:Logistics automation 1760:Plastic-coated paper 907:Resealable packaging 418:Seroux d'Agincourt, 184:Feast of San Gennaro 2422:Category: Packaging 2257:Packaging machinery 2066:Product development 1865:Tamper-evident band 1705:Modified atmosphere 1045:Foam food container 509:the chronicle flask 149:Christian catacombs 105:deuterated solvents 74:hermetically sealed 2385:Reusable packaging 2345:Industrial ecology 2106:Ultrasonic welding 2071:Production control 2021:Injection moulding 1906:Aseptic processing 1615:Corrugated plastic 1485:Steel and tin cans 1455:Shipping container 1393:Packet (container) 1130:Seasonal packaging 1030:Evidence packaging 1010:Currency packaging 1005:Cosmetic packaging 912:Reusable packaging 345: 321: 145: 125: 47: 36: 2428: 2427: 2390:Reverse logistics 2375:Plastic recycling 2247:Multihead weigher 2167:Cartoning machine 2162:Cap torque tester 2076:Quality assurance 2051:Plastic extrusion 2016:Induction sealing 1986:Extrusion coating 1845:Staple (fastener) 1815:Security printing 1650:Hot-melt adhesive 1223:Biodegradable bag 1065:Glass milk bottle 947:Tamper resistance 887:Package pilferage 862:Contract packager 648:978-0-429-20140-0 438:"Saint Januarius" 357:annealing quality 290:hydrofluoric acid 220:and later in the 197:) which held the 16:(Redirected from 2460: 2419: 2418: 2405:Waste management 2395:Source reduction 2212:Industrial robot 2116:Vacuum packaging 2041:Package tracking 1996:Glass production 1956:Corona treatment 1946:Containerization 1810:Screw cap (wine) 1725:Oxygen scavenger 1188:Aluminium bottle 1140:Screw cap (wine) 1085:Luxury packaging 917:Reuse of bottles 882:Package delivery 867:Edible packaging 852:Active packaging 829: 822: 815: 806: 778: 777: 765: 747: 741: 740: 738: 736: 731:on 12 March 2013 727:. 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161: 156: 154: 150: 142: 138: 134: 129: 121: 115:Early history 114: 112: 110: 106: 102: 98: 94: 91: 85: 83: 79: 75: 71: 66: 64: 60: 56: 52: 45: 40: 32: 19: 2443:Dosage forms 2430: 2311:Environment, 1926:Blow molding 1855:Stretch wrap 1785:Polyethylene 1775:Plastic wrap 1765:Plastic film 1750:Paper pallet 1685:Living hinge 1590:Coated paper 1470:Spray bottle 1450:Security bag 1443:Water sachet 1433:Salvage drum 1428:Retort pouch 1333:Glass bottle 1228:Blister pack 1197: 1193:Aluminum can 1160:Water bottle 1060:Gas cylinder 1035:Field ration 932:Shelf-stable 791: 752: 745: 733:. Retrieved 729:the original 704:. Retrieved 699: 690: 678:. Retrieved 630: 580: 577:SpringerPlus 576: 566: 534:(1): 93–94. 531: 527: 517: 508: 499: 485: 460: 456: 450: 441: 431: 419: 416:(in Italian) 411: 378: 361: 348: 346: 329:parenterally 326: 322: 298: 281: 262: 258:Schlenk line 254: 238:glass tubing 235: 194: 191:Holy Ampulla 188: 167: 157: 146: 137:Holy Ampulla 86: 67: 58: 54: 50: 48: 2207:Heat sealer 2172:Case sealer 2046:Papermaking 1966:Die cutting 1931:Calendering 1835:Shrink wrap 1710:Molded pulp 1695:Meat diaper 1660:Kraft paper 1640:Foam peanut 1630:Double seam 1600:Coextrusion 1570:Bubble wrap 1550:Bail handle 1495:Thermal bag 1418:Plastic bag 1233:Boil-in-bag 1165:Wine bottle 1150:Spray paint 1105:Popcorn bag 1100:Oyster pail 985:Beer bottle 735:14 February 528:Anaesthesia 305:oxymorphone 269:noble gases 242:gas torches 168:San Gennaro 143:of Clovis I 135:brings the 101:hygroscopic 2437:Categories 2287:Staple gun 2267:Palletizer 2157:Can seamer 2026:Lamination 1951:Converting 1840:Slip sheet 1755:Paperboard 1620:Cushioning 1580:Cellophane 1555:Bioplastic 1533:components 1520:Wooden box 1490:Tetra Brik 1413:Paper sack 1388:Multi-pack 1338:Gunny sack 1208:Bag-in-box 1175:Containers 1040:Flour sack 1025:Egg carton 1000:Coffee bag 980:Banana box 922:Shelf life 700:Making.com 403:References 375:Other uses 232:Production 206:coronation 133:Holy Ghost 90:injectable 2380:Recycling 2187:Drum pump 2130:Machinery 1981:Extrusion 1899:Processes 1870:Tear tape 1860:Susceptor 1850:Strapping 1805:Screw cap 1780:Polyester 1625:Desiccant 1529:Materials 1510:Unit load 1465:Skin pack 1408:Paper bag 1278:Clamshell 1020:Drink can 952:Wrap rage 836:Packaging 657:200544220 424:pp. 200-1 381:RFID tags 335:Standards 294:passivate 277:half-life 265:Xenon-133 228:in 1825. 199:anointing 176:Cathedral 172:Benevento 78:inert gas 2313:post-use 2202:Heat gun 2152:Calender 2061:Printing 1890:Velostat 1885:Tinplate 1720:Overwrap 1645:Gel pack 1635:Flip-top 1540:Adhesive 1475:Squround 1378:Mesh bag 1363:Jerrycan 1308:Envelope 1248:Bulk box 1125:Sand bag 1090:Milk bag 1075:Juicebox 990:Box wine 963:packages 609:26759754 558:41073335 550:12492680 477:14327645 422:(1810), 387:See also 287:molarity 214:Clovis I 204:for the 139:for the 82:glovebox 2036:Molding 1941:Coating 1936:Canning 1595:Coating 1585:Closure 1343:Inhaler 1198:Ampoule 1070:Growler 961:Product 843:General 706:15 June 680:15 June 600:4703599 393:Ampulla 208:of the 153:martyrs 141:baptism 51:ampoule 44:caesium 2420:  2355:Litter 2197:Filler 1740:Pallet 1438:Sachet 1303:Endcap 1268:Carton 1263:Carboy 1238:Bottle 1218:Barrel 845:topics 798:  770:  655:  645:  607:  597:  583:: 15. 556:  548:  475:  368:enamel 283:Teflon 210:French 180:Naples 59:ampule 53:(also 18:Ampule 1745:Paper 1665:Label 1565:BoPET 1288:Crate 653:S2CID 554:S2CID 364:paint 311:Usage 273:radon 271:save 160:blood 55:ampul 1575:Bung 1515:Vial 1505:Tube 1403:Pail 1298:Drum 1273:Chub 1258:Case 1253:Cage 796:ISBN 768:ISBN 737:2013 708:2022 682:2022 643:ISBN 605:PMID 546:PMID 473:PMID 303:and 131:The 107:and 63:vial 57:and 1670:Lid 1531:and 1373:Keg 1368:Jug 1358:Jar 1243:Box 1213:Bag 758:doi 635:doi 595:PMC 585:doi 536:doi 465:doi 366:or 202:oil 178:at 162:of 49:An 2439:: 766:. 716:^ 698:. 664:^ 651:, 641:, 629:, 617:^ 603:. 593:. 579:. 575:. 552:. 544:. 532:58 530:. 526:. 507:. 471:. 461:16 459:. 440:. 252:. 99:, 828:e 821:t 814:v 776:. 760:: 739:. 710:. 684:. 637:: 611:. 587:: 581:5 560:. 538:: 493:. 479:. 467:: 444:. 193:( 166:( 20:)

Index

Ampule


caesium
vial
pharmaceuticals
hermetically sealed
inert gas
glovebox
injectable
pharmaceuticals
tetrakis(triphenylphosphine)palladium(0)
hygroscopic
deuterated solvents
trifluoromethanesulfonic acid


Holy Ghost
Holy Ampulla
baptism
Christian catacombs
martyrs
blood
Saint Januarius
Benevento
Cathedral
Naples
Feast of San Gennaro
Holy Ampulla
anointing

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