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Aquaporin-1

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sites. The AQP1 monomer consists of six transmembrane alpha helices that are connected by five loops (A to E). The protein physically resembles channel proteins and is abundant in erythrocytes and renal tubes. The gene encoding this aquaporin is a possible candidate for disorders involving imbalance
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or AQP0). This gene encodes an aquaporin which functions as both a molecular water channel protein and as a non-selective cation channel gated by cyclic guanosine monophosphate (cGMP). It is a homotetramer with six bilayer spanning domains and
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van Hoek AN, Wiener MC, Verbavatz JM, Brown D, Lipniunas PH, Townsend RR, Verkman AS (February 1995). "Purification and structure-function analysis of native, PNGase F-treated, and endo-beta-galactosidase-treated CHIP28 water channels".
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Mitra, Alok K.; Ren, Gang; Reddy, Vijay S.; Cheng, Anchi; Froger, Alexandrine (2008). "The Architecture of a Water-Selective Pore in the Lipid Bilayer Visualized by Electron Crystallography in Vitreous Ice".
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Ripoche P, Goossens D, Devuyst O, Gane P, Colin Y, Verkman AS, Cartron JP (2006). "Role of RhAG and AQP1 in NH3 and CO2 gas transport in red cell ghosts: a stopped-flow analysis".
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Preston GM, Smith BL, Zeidel ML, Moulds JJ, Agre P (September 1994). "Mutations in aquaporin-1 in phenotypically normal humans without functional CHIP water channels".
327: 226: 2751: 2699: 1220: 149: 52: 1201: 4462: 4445: 4440: 4435: 4430: 4467: 3565: 2837: 2298:"Identification, purification, and partial characterization of a novel Mr 28,000 integral membrane protein from erythrocytes and renal tubules" 2163:
Preston GM, Carroll TP, Guggino WB, Agre P (April 1992). "Appearance of water channels in Xenopus oocytes expressing red cell CHIP28 protein".
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Zelinski T, Kaita H, Lewis M, Coghlan G, Philipps S, Belcher E, et al. (1988). "The Colton blood group locus. A linkage analysis".
313: 4203: 2678: 1452: 2796: 1459: 290: 2766: 1931: 4796: 3795: 3573: 2889: 1674: 1653: 4818: 1670: 212: 187: 5027: 2938: 2684: 1553: 2781: 1649: 4393: 3305: 2210:"Isolation of the cDNA for erythrocyte integral membrane protein of 28 kilodaltons: member of an ancient channel family" 129: 1823:"Single amino acids in the carboxyl terminal domain of aquaporin-1 contribute to cGMP-dependent ion channel activation" 4668: 2622:"Localization of the aquaporin 1 (AQP1) gene within a YAC contig containing the polymorphic markers D7S632 and D7S526" 326: 225: 2846: 2830: 5022: 3232: 2724: 319: 218: 2003:
Borgnia M, Nielsen S, Engel A, Agre P (2000). "Cellular and molecular biology of the aquaporin water channels".
5012: 3273: 3149: 2664: 2370:"Membrane topology of aquaporin CHIP. Analysis of functional epitope-scanning mutants by vectorial proteolysis" 1265: 137: 5017: 1246: 2263:"Erythrocyte Mr 28,000 transmembrane protein exists as a multisubunit oligomer similar to channel proteins" 5048: 3040: 3027: 3014: 2994: 2981: 2946: 1577: 1565: 2823: 1625: 2921: 2717: 2549:"Human red cell aquaporin CHIP. I. Molecular characterization of ABH and Colton blood group antigens" 2519: 2221: 2172: 1963: 1885: 1541: 201: 2069:
Yool AJ, Weinstein AM (April 2002). "New roles for old holes: ion channel function in aquaporin-1".
2815: 2690: 1410: 1363: 1353: 1349: 1345: 116: 4388: 3264: 2911: 2356: 2196: 2094: 2057: 161: 2405:"Biogenesis and transmembrane topology of the CHIP28 water channel at the endoplasmic reticulum" 1435: 1414: 1384: 1341: 1337: 3426: 2641: 2608: 2578: 2535: 2498: 2455: 2434: 2391: 2348: 2319: 2284: 2249: 2188: 2151: 2120: 2086: 2049: 2020: 1991: 1913: 1854: 1803: 1754: 109: 45: 4195: 3176: 2633: 2600: 2568: 2560: 2527: 2488: 2480: 2424: 2416: 2381: 2340: 2309: 2274: 2239: 2229: 2180: 2143: 2112: 2078: 2041: 2012: 1981: 1971: 1903: 1893: 1844: 1834: 1793: 1785: 1744: 1736: 564: 406: 337: 281: 236: 2344: 4731: 2871: 1607: 1557: 571: 381: 157: 2670: 1601:
are a family of small integral membrane proteins related to the major intrinsic protein (
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negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
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Keen TJ, Inglehearn CF, Patel RJ, Green ED, Peluso DC, Bhattacharya SS (January 1995).
2484: 2429: 2404: 1798: 1773: 1749: 1724: 2573: 2548: 2493: 2468: 2386: 2369: 2314: 2297: 2279: 2262: 1849: 1822: 1774:"Vasopressin V1a Receptors Regulate Cerebral Aquaporin 1 after Traumatic Brain Injury" 1135: 1130: 1125: 1120: 1115: 1110: 1105: 1100: 1095: 1090: 1085: 1080: 1075: 1070: 1065: 1060: 1055: 1050: 1045: 1040: 1035: 1030: 1025: 1020: 1015: 1010: 1005: 1000: 995: 990: 985: 980: 975: 970: 965: 960: 955: 950: 945: 940: 935: 930: 925: 920: 915: 910: 905: 900: 895: 890: 885: 880: 875: 870: 865: 860: 855: 850: 845: 840: 835: 830: 825: 820: 815: 810: 794: 789: 784: 779: 774: 769: 764: 759: 754: 749: 744: 739: 734: 729: 724: 719: 714: 709: 704: 699: 683: 678: 673: 668: 663: 658: 653: 648: 643: 638: 633: 628: 623: 618: 613: 5062: 4481: 4154: 2703: 2637: 2244: 2209: 2045: 2016: 1986: 1951: 1908: 1873: 1549: 600: 2360: 2098: 2061: 4834: 4225: 2200: 1569: 399: 178: 141: 2184: 2147: 165: 4764: 4759: 4754: 4749: 4636: 4475: 2850: 2446:
Li X, Yu H, Koide SS (February 1994). "The water channel gene in human uterus".
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National Center for Biotechnology Information, U.S. National Library of Medicine
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National Center for Biotechnology Information, U.S. National Library of Medicine
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Proceedings of the National Academy of Sciences of the United States of America
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Proceedings of the National Academy of Sciences of the United States of America
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Proceedings of the National Academy of Sciences of the United States of America
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Skach WR, Shi LB, Calayag MC, Frigeri A, Lingappa VR, Verkman AS (May 1994).
2234: 1536:, whose physiological function has been most thoroughly characterized in the 4829: 4739: 2531: 2082: 1976: 1620: 1598: 1533: 1165: 542: 420: 365: 352: 264: 251: 153: 2155: 2116: 2090: 2053: 2024: 1917: 1898: 1858: 1839: 1807: 1758: 2760:: STRUCTURE OF AQUAPORIN-1 AT 3.8 A RESOLUTION BY ELECTRON CRYSTALLOGRAPHY 2645: 2612: 2582: 2539: 2502: 2459: 2438: 2420: 2395: 2352: 2323: 2288: 2253: 2192: 1995: 1789: 1499: 1494: 4842: 4190: 3169: 3164: 3159: 3154: 3086: 3081: 2032:
Horster M (December 2000). "Embryonic epithelial membrane transporters".
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Ion Channels: From Atomic Resolution Physiology to Functional Genomics
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Smith BL, Preston GM, Spring FA, Anstee DJ, Agre P (September 1994).
2469:"The three-dimensional structure of human erythrocyte aquaporin CHIP" 1874:"Dynamic mechanisms of the membrane water channel aquaporin-1 (AQP1)" 1587: 1537: 1467: 1187: 2621: 4880: 4811: 4806: 4801: 4718: 4705: 4700: 4695: 4690: 4685: 4680: 4631: 4624: 4619: 4614: 4609: 4604: 4599: 4594: 4589: 4577: 4572: 4567: 4557: 4552: 4547: 4542: 4457: 4401: 4358: 4353: 4348: 4343: 4338: 4333: 4328: 4306: 4301: 4296: 4291: 4286: 4281: 4276: 4257: 4252: 4247: 4242: 4230: 4147: 4142: 4137: 4122: 4060: 4055: 4050: 4041: 4036: 4022: 4017: 4008: 4003: 3998: 3989: 3984: 3975: 3970: 3937: 3932: 3927: 3922: 3913: 3904: 3899: 3894: 3885: 3880: 3875: 3870: 3861: 3856: 3842: 3837: 3832: 3827: 3822: 3817: 3812: 3748: 3743: 3738: 3733: 3728: 3723: 3718: 3713: 3678: 3648: 3643: 3638: 3633: 3604: 3553: 3548: 3543: 3538: 3528: 3523: 3503: 3488: 3483: 3398: 3393: 3388: 3383: 3367: 3347: 3332: 3293: 3288: 3283: 3278: 3186: 3181: 2904: 2899: 2894: 1573: 1772:
Rauen K, Pop V, Trabold R, Badaut J, Plesnila N (February 2020).
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metanephric proximal convoluted tubule segment 2 development
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establishment or maintenance of actin cytoskeleton polarity
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Preston GM, Jung JS, Guggino WB, Agre P (January 1994).
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Denker BM, Smith BL, Kuhajda FP, Agre P (October 1988).
389: 120:, AQP-CHIP, CHIP28, CO, aquaporin 1 (Colton blood group) 554: 1932:"Entrez Gene: AQP1 aquaporin 1 (Colton blood group)" 629:
intracellular cGMP-activated cation channel activity
5003: 4827: 4716: 4512: 4410: 4386: 4188: 3794: 3699: 3564: 3437: 3304: 3263: 3225: 2937: 2882: 1428: 1403: 1377: 1336: 1952:"The aquaporin family of molecular water channels" 1666: 1664: 1662: 1645: 1643: 1641: 644:carbon dioxide transmembrane transporter activity 336: 235: 2448:Biochemistry and Molecular Biology International 2111:. Novartis Foundation Symposia. pp. 33–50. 2034:American Journal of Physiology. Renal Physiology 1106:metanephric proximal straight tubule development 1026:positive regulation of epithelial cell migration 659:potassium ion transmembrane transporter activity 2467:Walz T, Smith BL, Agre P, Engel A (July 1994). 846:positive regulation of fibroblast proliferation 624:nitric oxide transmembrane transporter activity 16:Protein-coding gene in the species Homo sapiens 1671:GRCm38: Ensembl release 89: ENSMUSG00000004655 1116:metanephric glomerulus vasculature development 2831: 2805:: Crystal Structure of the AQP1 water channel 2725: 1021:positive regulation of lamellipodium assembly 8: 1101:metanephric descending thin limb development 1650:GRCh38: Ensembl release 89: ENSG00000240583 901:cellular response to dexamethasone stimulus 664:glycerol transmembrane transporter activity 619:ammonium transmembrane transporter activity 5000: 4987: 4185: 4172: 3434: 3418: 3222: 3206: 2879: 2863: 2838: 2824: 2816: 2775:: A REFINED STRUCTURE OF HUMAN AQUAPORIN 1 2732: 2718: 2710: 2700:United States National Library of Medicine 1333: 1161: 956:multicellular organismal water homeostasis 596: 377: 276: 173: 63: 2663:at the U.S. National Library of Medicine 2572: 2492: 2428: 2385: 2313: 2278: 2243: 2233: 1985: 1975: 1907: 1897: 1848: 1838: 1797: 1748: 2698:This article incorporates text from the 896:negative regulation of apoptotic process 876:cellular response to inorganic substance 816:cellular response to mechanical stimulus 654:water transmembrane transporter activity 2747: 1637: 1552:, and in the descending portion of the 946:positive regulation of saliva secretion 2345:10.1046/j.1537-2995.1988.28588337331.x 971:cellular response to hydrogen peroxide 841:carbon dioxide transmembrane transport 18: 2553:The Journal of Clinical Investigation 1051:positive regulation of cell migration 981:potassium ion transmembrane transport 750:integral component of plasma membrane 341: 302: 297: 240: 199: 194: 7: 2208:Preston GM, Agre P (December 1991). 710:symbiont-containing vacuole membrane 4204:Calcium-activated chloride channels 2374:The Journal of Biological Chemistry 2302:The Journal of Biological Chemistry 2267:The Journal of Biological Chemistry 1725:"Aquaporin and Blood Brain Barrier" 1723:Francesca, B.; Rezzani, R. (2010). 1544:and apical plasma membranes of the 906:positive regulation of angiogenesis 3274:Amiloride-sensitive cation channel 2790:: CRYSTAL STRUCTURE OF AQUAPORIN-1 2485:10.1002/j.1460-2075.1994.tb06597.x 2136:Transfusion Clinique et Biologique 1821:Boassa D, Yool AJ (October 2003). 1425: 1400: 1374: 1309: 1282: 1256: 1237: 1211: 1192: 811:cellular response to retinoic acid 639:transmembrane transporter activity 559: 513:choroid plexus of fourth ventricle 477: 415: 394: 14: 1556:. Additionally, it is found in 1522:that in humans is encoded by the 826:cellular response to nitric oxide 2795: 2780: 2765: 2750: 2672:Gallery of Aquaporin Simulations 2046:10.1152/ajprenal.2000.279.6.F982 2017:10.1146/annurev.biochem.68.1.425 986:ammonium transmembrane transport 926:cellular response to mercury ion 871:cellular response to salt stress 570: 563: 325: 318: 312: 289: 224: 217: 211: 186: 27: 4797:Voltage-dependent anion channel 2890:Inositol trisphosphate receptor 2261:Smith BL, Agre P (April 1991). 961:transepithelial water transport 821:cellular response to copper ion 4819:General bacterial porin family 2071:News in Physiological Sciences 1872:Kong Y, Ma J (December 2001). 1583:Neural AQP-1 are regulated by 1071:hyperosmotic salinity response 1061:secretory granule organization 991:cation transmembrane transport 936:cellular hyperosmotic response 730:integral component of membrane 581:More reference expression data 543:More reference expression data 1: 2387:10.1016/S0021-9258(17)42079-5 2315:10.1016/S0021-9258(19)37635-5 2280:10.1016/S0021-9258(18)38133-X 2005:Annual Review of Biochemistry 1548:, the descending limb of the 1086:camera-type eye morphogenesis 1041:lateral ventricle development 976:cerebrospinal fluid secretion 310: 209: 2638:10.1016/0888-7543(95)80070-3 2185:10.1126/science.256.5055.385 2148:10.1016/j.tracli.2006.03.004 1532:AQP-1 is a widely expressed 831:cellular response to hypoxia 5069:Genes on human chromosome 7 2409:The Journal of Cell Biology 1131:ion transmembrane transport 866:cellular response to stress 775:symbiont-containing vacuole 760:basolateral plasma membrane 5090: 5074:Integral membrane proteins 4238:Chloride Channel Accessory 2847:Membrane transport protein 2689:gene details page in the 1741:10.2174/157015910791233132 1611:in ocular fluid movement. 1036:sensory perception of pain 856:pancreatic juice secretion 634:potassium channel activity 5044: 4999: 4986: 4184: 4171: 3433: 3417: 3233:Epithelial sodium channel 3221: 3205: 2878: 2862: 2745: 1729:Current Neuropharmacology 1706:"Mouse PubMed Reference:" 1688:"Human PubMed Reference:" 1498: 1493: 1489: 1482: 1466: 1447: 1432: 1407: 1396: 1381: 1360: 1329: 1316: 1312: 1289: 1285: 1276: 1263: 1259: 1244: 1240: 1231: 1218: 1214: 1199: 1195: 1186: 1171: 1164: 1160: 1144: 861:cGMP biosynthetic process 836:cellular response to cAMP 679:identical protein binding 599: 595: 578: 562: 553: 540: 489: 480: 431:Descending thoracic aorta 427: 418: 388: 380: 376: 359: 346: 309: 288: 279: 275: 258: 245: 208: 185: 176: 172: 127: 124: 114: 107: 102: 71: 66: 49: 44: 39: 35: 26: 21: 3150:Cation channels of sperm 2665:Medical Subject Headings 2235:10.1073/pnas.88.24.11110 1950:Knepper MA (July 1994). 966:carbon dioxide transport 443:tendon of biceps brachii 2532:10.1126/science.7521540 2083:10.1152/nips.01372.2001 1977:10.1073/pnas.91.14.6255 1460:Chr 6: 55.31 – 55.33 Mb 1453:Chr 7: 30.91 – 30.93 Mb 1136:transmembrane transport 1126:cGMP-mediated signaling 1091:corticotropin secretion 1001:potassium ion transport 951:renal water homeostasis 886:cellular response to UV 881:cell volume homeostasis 674:ephrin receptor binding 447:upper lobe of left lung 2117:10.1002/0470868759.ch4 1899:10.1073/pnas.251507998 1840:10.1186/1472-6793-3-12 1778:Journal of Neurotrauma 1578:central nervous system 1566:gastrointestinal tract 1540:. It is found in the 1096:renal water absorption 931:nitric oxide transport 725:apical plasma membrane 669:water channel activity 3226:Constitutively active 2421:10.1083/jcb.125.4.803 1790:10.1089/neu.2019.6653 1626:Colton antigen system 1011:hyperosmotic response 996:glomerular filtration 941:bicarbonate transport 916:renal water transport 795:extracellular exosome 755:brush border membrane 745:basal plasma membrane 451:right coronary artery 2683:genome location and 1076:response to estrogen 851:cellular homeostasis 614:transporter activity 343:6 B3|6 27.38 cM 304:Chromosome 6 (mouse) 202:Chromosome 7 (human) 67:List of PDB id codes 40:Available structures 4993:By gating mechanism 2691:UCSC Genome Browser 2605:10.1021/bi00007a015 2524:1994Sci...265.1585P 2226:1991PNAS...8811110P 2177:1992Sci...256..385P 1968:1994PNAS...91.6255K 1890:2001PNAS...9814345K 1590:receptor activity. 1016:response to hormone 740:apical part of cell 4520:TRP cation channel 4418:CNG cation channel 3701:Tandem pore domain 2912:Ryanodine receptor 2702:, which is in the 1266:ENSMUSG00000004655 1031:glycerol transport 804:Biological process 693:Cellular component 607:Molecular function 501:tibiofemoral joint 467:lower lobe of lung 5056: 5055: 5040: 5039: 5036: 5035: 5028:Stretch-activated 5005:Ion channel class 4982: 4981: 4978: 4977: 4167: 4166: 4163: 4162: 3439:Calcium-activated 3427:Potassium channel 3413: 3412: 3409: 3408: 3201: 3200: 3197: 3196: 2813: 2812: 2565:10.1172/JCI117418 2126:978-0-470-84375-8 1509: 1508: 1505: 1504: 1478: 1477: 1443: 1442: 1422: 1421: 1392: 1391: 1371: 1370: 1325: 1324: 1306: 1305: 1272: 1271: 1253: 1252: 1227: 1226: 1208: 1207: 1156: 1155: 1056:secretion by cell 1046:water homeostasis 785:neuron projection 591: 590: 587: 586: 549: 548: 536: 535: 474: 473: 372: 371: 271: 270: 98: 97: 94: 93: 50:Ortholog search: 5081: 5001: 4988: 4196:Chloride channel 4186: 4173: 3566:Inward-rectifier 3435: 3419: 3223: 3207: 3177:Two-pore channel 2880: 2864: 2840: 2833: 2826: 2817: 2799: 2784: 2769: 2754: 2734: 2727: 2720: 2711: 2649: 2616: 2586: 2576: 2543: 2518:(5178): 1585–7. 2506: 2496: 2473:The EMBO Journal 2463: 2442: 2432: 2399: 2389: 2364: 2327: 2317: 2308:(30): 15634–42. 2292: 2282: 2257: 2247: 2237: 2204: 2159: 2130: 2102: 2065: 2028: 1999: 1989: 1979: 1936: 1935: 1928: 1922: 1921: 1911: 1901: 1869: 1863: 1862: 1852: 1842: 1818: 1812: 1811: 1801: 1769: 1763: 1762: 1752: 1720: 1714: 1713: 1702: 1696: 1695: 1684: 1678: 1668: 1657: 1647: 1546:proximal tubules 1491: 1490: 1462: 1455: 1438: 1426: 1417: 1401: 1397:RefSeq (protein) 1387: 1375: 1366: 1334: 1310: 1283: 1257: 1238: 1212: 1193: 1162: 705:nuclear membrane 684:channel activity 597: 583: 574: 567: 560: 545: 509:fourth ventricle 485: 483:Top expressed in 478: 423: 421:Top expressed in 416: 395: 378: 368: 355: 344: 329: 322: 316: 305: 293: 277: 267: 254: 243: 228: 221: 215: 204: 190: 174: 168: 166:AQP1 - orthologs 119: 112: 89: 64: 58: 37: 36: 31: 19: 5089: 5088: 5084: 5083: 5082: 5080: 5079: 5078: 5059: 5058: 5057: 5052: 5032: 4995: 4974: 4823: 4722: 4712: 4508: 4406: 4382: 4180: 4159: 4073: 3950: 3807: 3790: 3695: 3659: 3629: 3585: 3577: 3560: 3514: 3429: 3405: 3378: 3317: 3300: 3259: 3217: 3193: 3076: 3048: 3035: 3022: 3002: 2989: 2954: 2933: 2874: 2872:Calcium channel 2858: 2844: 2814: 2809: 2806: 2800: 2791: 2785: 2776: 2770: 2761: 2755: 2741: 2738: 2657: 2652: 2619: 2589: 2546: 2509: 2479:(13): 2985–93. 2466: 2445: 2402: 2367: 2330: 2295: 2273:(10): 6407–15. 2260: 2220:(24): 11110–4. 2207: 2171:(5055): 385–7. 2162: 2142:(1–2): 117–22. 2133: 2127: 2105: 2068: 2031: 2002: 1949: 1945: 1943:Further reading 1940: 1939: 1930: 1929: 1925: 1884:(25): 14345–9. 1871: 1870: 1866: 1820: 1819: 1815: 1771: 1770: 1766: 1722: 1721: 1717: 1704: 1703: 1699: 1686: 1685: 1681: 1669: 1660: 1648: 1639: 1634: 1617: 1608:N-glycosylation 1596: 1558:red blood cells 1500:View/Edit Mouse 1495:View/Edit Human 1458: 1451: 1448:Location (UCSC) 1434: 1413: 1409: 1383: 1362: 1356: 1352: 1348: 1344: 1340: 1298: 1294: 1247:ENSG00000240583 1140: 1081:lipid digestion 1006:water transport 799: 735:plasma membrane 688: 649:protein binding 579: 569: 568: 541: 532: 527: 523: 519: 515: 511: 507: 503: 499: 497:right lung lobe 495: 481: 470: 465: 461: 457: 453: 449: 445: 441: 437: 435:ascending aorta 433: 419: 363: 350: 342: 332: 331: 330: 323: 303: 280:Gene location ( 262: 249: 241: 231: 230: 229: 222: 200: 177:Gene location ( 128: 115: 108: 73: 51: 17: 12: 11: 5: 5087: 5085: 5077: 5076: 5071: 5061: 5060: 5054: 5053: 5045: 5042: 5041: 5038: 5037: 5034: 5033: 5031: 5030: 5025: 5020: 5015: 5009: 5007: 4997: 4996: 4991: 4984: 4983: 4980: 4979: 4976: 4975: 4973: 4972: 4967: 4966: 4965: 4964: 4963: 4958: 4953: 4945: 4944: 4943: 4938: 4933: 4925: 4924: 4923: 4918: 4913: 4908: 4903: 4898: 4893: 4885: 4884: 4883: 4878: 4873: 4868: 4863: 4858: 4853: 4839: 4837: 4825: 4824: 4822: 4821: 4816: 4815: 4814: 4809: 4804: 4794: 4793: 4792: 4787: 4782: 4777: 4772: 4767: 4762: 4757: 4752: 4747: 4736: 4734: 4720: 4714: 4713: 4711: 4710: 4709: 4708: 4703: 4698: 4693: 4688: 4683: 4673: 4672: 4671: 4666: 4656: 4651: 4650: 4649: 4644: 4639: 4629: 4628: 4627: 4622: 4617: 4612: 4607: 4602: 4597: 4592: 4582: 4581: 4580: 4575: 4570: 4565: 4560: 4555: 4550: 4545: 4535: 4524: 4522: 4510: 4509: 4507: 4506: 4505: 4504: 4499: 4494: 4489: 4484: 4472: 4471: 4470: 4465: 4460: 4450: 4449: 4448: 4443: 4438: 4433: 4422: 4420: 4408: 4407: 4405: 4404: 4398: 4396: 4394:Proton channel 4384: 4383: 4381: 4380: 4379: 4378: 4373: 4363: 4362: 4361: 4356: 4351: 4346: 4341: 4336: 4331: 4321: 4320: 4319: 4314: 4309: 4304: 4299: 4294: 4289: 4284: 4279: 4269: 4264: 4263: 4262: 4261: 4260: 4255: 4250: 4245: 4235: 4234: 4233: 4228: 4218: 4217: 4216: 4200: 4198: 4182: 4181: 4176: 4169: 4168: 4165: 4164: 4161: 4160: 4158: 4157: 4152: 4151: 4150: 4145: 4140: 4130: 4125: 4120: 4119: 4118: 4113: 4108: 4103: 4093: 4092: 4091: 4086: 4081: 4071: 4066: 4065: 4064: 4063: 4058: 4053: 4046: 4045: 4044: 4039: 4034: 4027: 4026: 4025: 4020: 4013: 4012: 4011: 4006: 4001: 3994: 3993: 3992: 3987: 3980: 3979: 3978: 3973: 3968: 3963: 3958: 3948: 3943: 3942: 3941: 3940: 3935: 3930: 3925: 3918: 3917: 3916: 3909: 3908: 3907: 3902: 3897: 3890: 3889: 3888: 3883: 3878: 3873: 3866: 3865: 3864: 3859: 3852: 3851: 3850: 3845: 3840: 3835: 3830: 3825: 3820: 3815: 3805: 3800: 3798: 3792: 3791: 3789: 3788: 3787: 3786: 3781: 3776: 3771: 3766: 3761: 3756: 3751: 3746: 3741: 3736: 3731: 3726: 3721: 3716: 3705: 3703: 3697: 3696: 3694: 3693: 3692: 3691: 3686: 3681: 3676: 3671: 3666: 3657: 3653: 3652: 3651: 3646: 3641: 3636: 3627: 3619: 3618: 3617: 3612: 3607: 3602: 3597: 3592: 3583: 3579: 3575: 3570: 3568: 3562: 3561: 3559: 3558: 3557: 3556: 3551: 3546: 3541: 3536: 3531: 3526: 3521: 3512: 3508: 3507: 3506: 3498: 3497: 3496: 3491: 3486: 3476: 3475: 3474: 3469: 3464: 3459: 3454: 3443: 3441: 3431: 3430: 3422: 3415: 3414: 3411: 3410: 3407: 3406: 3404: 3403: 3402: 3401: 3396: 3391: 3386: 3376: 3372: 3371: 3370: 3365: 3360: 3355: 3350: 3345: 3340: 3335: 3330: 3325: 3315: 3310: 3308: 3302: 3301: 3299: 3298: 3297: 3296: 3291: 3286: 3281: 3270: 3268: 3261: 3260: 3258: 3257: 3256: 3255: 3250: 3245: 3240: 3229: 3227: 3219: 3218: 3215:Sodium channel 3210: 3203: 3202: 3199: 3198: 3195: 3194: 3192: 3191: 3190: 3189: 3184: 3174: 3173: 3172: 3167: 3162: 3157: 3146: 3145: 3144: 3143: 3138: 3133: 3128: 3118: 3117: 3116: 3111: 3106: 3101: 3091: 3090: 3089: 3084: 3074: 3069: 3068: 3067: 3066: 3061: 3056: 3046: 3038: 3033: 3025: 3020: 3012: 3011: 3010: 3000: 2992: 2987: 2979: 2978: 2977: 2972: 2967: 2962: 2952: 2943: 2941: 2935: 2934: 2932: 2931: 2930: 2929: 2924: 2919: 2909: 2908: 2907: 2902: 2897: 2886: 2884: 2876: 2875: 2867: 2860: 2859: 2845: 2843: 2842: 2835: 2828: 2820: 2811: 2810: 2808: 2807: 2801: 2794: 2792: 2786: 2779: 2777: 2771: 2764: 2762: 2756: 2749: 2746: 2743: 2742: 2739: 2737: 2736: 2729: 2722: 2714: 2695: 2694: 2675: 2668: 2656: 2655:External links 2653: 2651: 2650: 2632:(2): 599–600. 2617: 2587: 2544: 2507: 2464: 2443: 2400: 2380:(3): 1668–73. 2365: 2328: 2293: 2258: 2205: 2160: 2131: 2125: 2103: 2066: 2040:(6): F982-96. 2029: 2000: 1962:(14): 6255–8. 1946: 1944: 1941: 1938: 1937: 1923: 1864: 1827:BMC Physiology 1813: 1784:(4): 665–674. 1764: 1715: 1697: 1679: 1658: 1636: 1635: 1633: 1630: 1629: 1628: 1623: 1616: 1613: 1595: 1592: 1507: 1506: 1503: 1502: 1497: 1487: 1486: 1480: 1479: 1476: 1475: 1473: 1471: 1464: 1463: 1456: 1449: 1445: 1444: 1441: 1440: 1430: 1429: 1423: 1420: 1419: 1405: 1404: 1398: 1394: 1393: 1390: 1389: 1379: 1378: 1372: 1369: 1368: 1358: 1357: 1331: 1327: 1326: 1323: 1322: 1314: 1313: 1307: 1304: 1303: 1287: 1286: 1280: 1274: 1273: 1270: 1269: 1261: 1260: 1254: 1251: 1250: 1242: 1241: 1235: 1229: 1228: 1225: 1224: 1216: 1215: 1209: 1206: 1205: 1197: 1196: 1190: 1184: 1183: 1178: 1173: 1169: 1168: 1158: 1157: 1154: 1153: 1142: 1141: 1139: 1138: 1133: 1128: 1123: 1118: 1113: 1108: 1103: 1098: 1093: 1088: 1083: 1078: 1073: 1068: 1063: 1058: 1053: 1048: 1043: 1038: 1033: 1028: 1023: 1018: 1013: 1008: 1003: 998: 993: 988: 983: 978: 973: 968: 963: 958: 953: 948: 943: 938: 933: 928: 923: 918: 913: 908: 903: 898: 893: 888: 883: 878: 873: 868: 863: 858: 853: 848: 843: 838: 833: 828: 823: 818: 813: 807: 805: 801: 800: 798: 797: 792: 787: 782: 777: 772: 767: 762: 757: 752: 747: 742: 737: 732: 727: 722: 717: 712: 707: 702: 696: 694: 690: 689: 687: 686: 681: 676: 671: 666: 661: 656: 651: 646: 641: 636: 631: 626: 621: 616: 610: 608: 604: 603: 593: 592: 589: 588: 585: 584: 576: 575: 557: 551: 550: 547: 546: 538: 537: 534: 533: 531: 530: 526: 522: 518: 514: 510: 506: 502: 498: 494: 490: 487: 486: 475: 472: 471: 469: 468: 464: 460: 456: 452: 448: 444: 440: 436: 432: 428: 425: 424: 412: 411: 403: 392: 386: 385: 382:RNA expression 374: 373: 370: 369: 361: 357: 356: 348: 345: 340: 334: 333: 324: 317: 311: 307: 306: 301: 295: 294: 286: 285: 273: 272: 269: 268: 260: 256: 255: 247: 244: 239: 233: 232: 223: 216: 210: 206: 205: 198: 192: 191: 183: 182: 170: 169: 126: 122: 121: 113: 105: 104: 100: 99: 96: 95: 92: 91: 69: 68: 60: 59: 48: 42: 41: 33: 32: 24: 23: 15: 13: 10: 9: 6: 4: 3: 2: 5086: 5075: 5072: 5070: 5067: 5066: 5064: 5051: 5050: 5043: 5029: 5026: 5024: 5023:Voltage-gated 5021: 5019: 5016: 5014: 5011: 5010: 5008: 5006: 5002: 4998: 4994: 4989: 4985: 4971: 4968: 4962: 4959: 4957: 4954: 4952: 4949: 4948: 4946: 4942: 4939: 4937: 4934: 4932: 4929: 4928: 4926: 4922: 4919: 4917: 4914: 4912: 4909: 4907: 4904: 4902: 4899: 4897: 4894: 4892: 4889: 4888: 4886: 4882: 4879: 4877: 4874: 4872: 4869: 4867: 4864: 4862: 4859: 4857: 4854: 4852: 4849: 4848: 4846: 4845: 4844: 4841: 4840: 4838: 4836: 4833: 4831: 4826: 4820: 4817: 4813: 4810: 4808: 4805: 4803: 4800: 4799: 4798: 4795: 4791: 4788: 4786: 4783: 4781: 4778: 4776: 4773: 4771: 4768: 4766: 4763: 4761: 4758: 4756: 4753: 4751: 4748: 4746: 4743: 4742: 4741: 4738: 4737: 4735: 4733: 4730: 4728: 4724: 4715: 4707: 4704: 4702: 4699: 4697: 4694: 4692: 4689: 4687: 4684: 4682: 4679: 4678: 4677: 4674: 4670: 4667: 4665: 4662: 4661: 4660: 4657: 4655: 4652: 4648: 4645: 4643: 4640: 4638: 4635: 4634: 4633: 4630: 4626: 4623: 4621: 4618: 4616: 4613: 4611: 4608: 4606: 4603: 4601: 4598: 4596: 4593: 4591: 4588: 4587: 4586: 4583: 4579: 4576: 4574: 4571: 4569: 4566: 4564: 4561: 4559: 4556: 4554: 4551: 4549: 4546: 4544: 4541: 4540: 4539: 4536: 4533: 4529: 4526: 4525: 4523: 4521: 4518: 4516: 4511: 4503: 4500: 4498: 4495: 4493: 4490: 4488: 4485: 4483: 4480: 4479: 4478: 4477: 4473: 4469: 4466: 4464: 4461: 4459: 4456: 4455: 4454: 4451: 4447: 4444: 4442: 4439: 4437: 4434: 4432: 4429: 4428: 4427: 4424: 4423: 4421: 4419: 4416: 4414: 4409: 4403: 4400: 4399: 4397: 4395: 4392: 4390: 4385: 4377: 4374: 4372: 4369: 4368: 4367: 4364: 4360: 4357: 4355: 4352: 4350: 4347: 4345: 4342: 4340: 4337: 4335: 4332: 4330: 4327: 4326: 4325: 4322: 4318: 4315: 4313: 4310: 4308: 4305: 4303: 4300: 4298: 4295: 4293: 4290: 4288: 4285: 4283: 4280: 4278: 4275: 4274: 4273: 4270: 4268: 4265: 4259: 4256: 4254: 4251: 4249: 4246: 4244: 4241: 4240: 4239: 4236: 4232: 4229: 4227: 4224: 4223: 4222: 4219: 4215: 4212: 4211: 4210: 4207: 4206: 4205: 4202: 4201: 4199: 4197: 4194: 4192: 4187: 4183: 4179: 4178:Miscellaneous 4174: 4170: 4156: 4155:Shaker (gene) 4153: 4149: 4146: 4144: 4141: 4139: 4136: 4135: 4134: 4131: 4129: 4128:minK/ISK-like 4126: 4124: 4121: 4117: 4114: 4112: 4109: 4107: 4104: 4102: 4099: 4098: 4097: 4094: 4090: 4087: 4085: 4082: 4080: 4077: 4076: 4075: 4068: 4067: 4062: 4059: 4057: 4054: 4052: 4049: 4048: 4047: 4043: 4040: 4038: 4035: 4033: 4030: 4029: 4028: 4024: 4021: 4019: 4016: 4015: 4014: 4010: 4007: 4005: 4002: 4000: 3997: 3996: 3995: 3991: 3988: 3986: 3983: 3982: 3981: 3977: 3974: 3972: 3969: 3967: 3964: 3962: 3959: 3957: 3954: 3953: 3952: 3945: 3944: 3939: 3936: 3934: 3931: 3929: 3926: 3924: 3921: 3920: 3919: 3915: 3912: 3911: 3910: 3906: 3903: 3901: 3898: 3896: 3893: 3892: 3891: 3887: 3884: 3882: 3879: 3877: 3874: 3872: 3869: 3868: 3867: 3863: 3860: 3858: 3855: 3854: 3853: 3849: 3846: 3844: 3841: 3839: 3836: 3834: 3831: 3829: 3826: 3824: 3821: 3819: 3816: 3814: 3811: 3810: 3809: 3802: 3801: 3799: 3797: 3796:Voltage-gated 3793: 3785: 3782: 3780: 3777: 3775: 3772: 3770: 3767: 3765: 3762: 3760: 3757: 3755: 3752: 3750: 3747: 3745: 3742: 3740: 3737: 3735: 3732: 3730: 3727: 3725: 3722: 3720: 3717: 3715: 3712: 3711: 3710: 3707: 3706: 3704: 3702: 3698: 3690: 3687: 3685: 3682: 3680: 3677: 3675: 3672: 3670: 3667: 3665: 3662: 3661: 3660: 3654: 3650: 3647: 3645: 3642: 3640: 3637: 3635: 3632: 3631: 3630: 3623: 3620: 3616: 3613: 3611: 3608: 3606: 3603: 3601: 3598: 3596: 3593: 3591: 3588: 3587: 3586: 3580: 3578: 3572: 3571: 3569: 3567: 3563: 3555: 3552: 3550: 3547: 3545: 3542: 3540: 3537: 3535: 3532: 3530: 3527: 3525: 3522: 3520: 3517: 3516: 3515: 3509: 3505: 3502: 3501: 3499: 3495: 3492: 3490: 3487: 3485: 3482: 3481: 3480: 3477: 3473: 3470: 3468: 3465: 3463: 3460: 3458: 3455: 3453: 3450: 3449: 3448: 3445: 3444: 3442: 3440: 3436: 3432: 3428: 3425: 3420: 3416: 3400: 3397: 3395: 3392: 3390: 3387: 3385: 3382: 3381: 3380: 3373: 3369: 3366: 3364: 3361: 3359: 3356: 3354: 3351: 3349: 3346: 3344: 3341: 3339: 3336: 3334: 3331: 3329: 3326: 3324: 3321: 3320: 3319: 3312: 3311: 3309: 3307: 3306:Voltage-gated 3303: 3295: 3292: 3290: 3287: 3285: 3282: 3280: 3277: 3276: 3275: 3272: 3271: 3269: 3266: 3262: 3254: 3251: 3249: 3246: 3244: 3241: 3239: 3236: 3235: 3234: 3231: 3230: 3228: 3224: 3220: 3216: 3213: 3208: 3204: 3188: 3185: 3183: 3180: 3179: 3178: 3175: 3171: 3168: 3166: 3163: 3161: 3158: 3156: 3153: 3152: 3151: 3148: 3147: 3142: 3139: 3137: 3134: 3132: 3129: 3127: 3124: 3123: 3122: 3119: 3115: 3112: 3110: 3107: 3105: 3102: 3100: 3097: 3096: 3095: 3092: 3088: 3085: 3083: 3080: 3079: 3078: 3071: 3070: 3065: 3062: 3060: 3057: 3055: 3052: 3051: 3050: 3042: 3039: 3037: 3029: 3026: 3024: 3016: 3013: 3009: 3006: 3005: 3004: 2996: 2993: 2991: 2983: 2980: 2976: 2973: 2971: 2968: 2966: 2963: 2961: 2958: 2957: 2956: 2948: 2945: 2944: 2942: 2940: 2939:Voltage-gated 2936: 2928: 2925: 2923: 2920: 2918: 2915: 2914: 2913: 2910: 2906: 2903: 2901: 2898: 2896: 2893: 2892: 2891: 2888: 2887: 2885: 2881: 2877: 2873: 2870: 2865: 2861: 2856: 2852: 2848: 2841: 2836: 2834: 2829: 2827: 2822: 2821: 2818: 2804: 2798: 2793: 2789: 2783: 2778: 2774: 2768: 2763: 2759: 2753: 2748: 2744: 2735: 2730: 2728: 2723: 2721: 2716: 2715: 2712: 2708: 2707: 2705: 2704:public domain 2701: 2692: 2688: 2687: 2682: 2681: 2676: 2674: 2673: 2669: 2666: 2662: 2659: 2658: 2654: 2647: 2643: 2639: 2635: 2631: 2627: 2623: 2618: 2614: 2610: 2606: 2602: 2599:(7): 2212–9. 2598: 2594: 2588: 2584: 2580: 2575: 2570: 2566: 2562: 2559:(3): 1043–9. 2558: 2554: 2550: 2545: 2541: 2537: 2533: 2529: 2525: 2521: 2517: 2513: 2508: 2504: 2500: 2495: 2490: 2486: 2482: 2478: 2474: 2470: 2465: 2461: 2457: 2453: 2449: 2444: 2440: 2436: 2431: 2426: 2422: 2418: 2415:(4): 803–15. 2414: 2410: 2406: 2401: 2397: 2393: 2388: 2383: 2379: 2375: 2371: 2366: 2362: 2358: 2354: 2350: 2346: 2342: 2338: 2334: 2329: 2325: 2321: 2316: 2311: 2307: 2303: 2299: 2294: 2290: 2286: 2281: 2276: 2272: 2268: 2264: 2259: 2255: 2251: 2246: 2241: 2236: 2231: 2227: 2223: 2219: 2215: 2211: 2206: 2202: 2198: 2194: 2190: 2186: 2182: 2178: 2174: 2170: 2166: 2161: 2157: 2153: 2149: 2145: 2141: 2137: 2132: 2128: 2122: 2118: 2114: 2110: 2104: 2100: 2096: 2092: 2088: 2084: 2080: 2076: 2072: 2067: 2063: 2059: 2055: 2051: 2047: 2043: 2039: 2035: 2030: 2026: 2022: 2018: 2014: 2010: 2006: 2001: 1997: 1993: 1988: 1983: 1978: 1973: 1969: 1965: 1961: 1957: 1953: 1948: 1947: 1942: 1933: 1927: 1924: 1919: 1915: 1910: 1905: 1900: 1895: 1891: 1887: 1883: 1879: 1875: 1868: 1865: 1860: 1856: 1851: 1846: 1841: 1836: 1832: 1828: 1824: 1817: 1814: 1809: 1805: 1800: 1795: 1791: 1787: 1783: 1779: 1775: 1768: 1765: 1760: 1756: 1751: 1746: 1742: 1738: 1734: 1730: 1726: 1719: 1716: 1711: 1707: 1701: 1698: 1693: 1689: 1683: 1680: 1676: 1672: 1667: 1665: 1663: 1659: 1655: 1651: 1646: 1644: 1642: 1638: 1631: 1627: 1624: 1622: 1619: 1618: 1614: 1612: 1609: 1604: 1600: 1593: 1591: 1589: 1586: 1581: 1579: 1575: 1571: 1567: 1563: 1559: 1555: 1551: 1550:loop of Henle 1547: 1543: 1539: 1535: 1534:water channel 1530: 1528: 1525: 1521: 1517: 1513: 1501: 1496: 1492: 1488: 1485: 1481: 1474: 1472: 1469: 1465: 1461: 1457: 1454: 1450: 1446: 1439: 1437: 1431: 1427: 1424: 1418: 1416: 1412: 1406: 1402: 1399: 1395: 1388: 1386: 1380: 1376: 1373: 1367: 1365: 1359: 1355: 1351: 1347: 1343: 1339: 1335: 1332: 1330:RefSeq (mRNA) 1328: 1321: 1320: 1315: 1311: 1308: 1302: 1301: 1297: 1293: 1288: 1284: 1281: 1279: 1275: 1268: 1267: 1262: 1258: 1255: 1249: 1248: 1243: 1239: 1236: 1234: 1230: 1223: 1222: 1217: 1213: 1210: 1204: 1203: 1198: 1194: 1191: 1189: 1185: 1182: 1179: 1177: 1174: 1170: 1167: 1163: 1159: 1152: 1148: 1143: 1137: 1134: 1132: 1129: 1127: 1124: 1122: 1119: 1117: 1114: 1112: 1109: 1107: 1104: 1102: 1099: 1097: 1094: 1092: 1089: 1087: 1084: 1082: 1079: 1077: 1074: 1072: 1069: 1067: 1066:wound healing 1064: 1062: 1059: 1057: 1054: 1052: 1049: 1047: 1044: 1042: 1039: 1037: 1034: 1032: 1029: 1027: 1024: 1022: 1019: 1017: 1014: 1012: 1009: 1007: 1004: 1002: 999: 997: 994: 992: 989: 987: 984: 982: 979: 977: 974: 972: 969: 967: 964: 962: 959: 957: 954: 952: 949: 947: 944: 942: 939: 937: 934: 932: 929: 927: 924: 922: 919: 917: 914: 912: 911:odontogenesis 909: 907: 904: 902: 899: 897: 894: 892: 889: 887: 884: 882: 879: 877: 874: 872: 869: 867: 864: 862: 859: 857: 854: 852: 849: 847: 844: 842: 839: 837: 834: 832: 829: 827: 824: 822: 819: 817: 814: 812: 809: 808: 806: 803: 802: 796: 793: 791: 790:axon terminus 788: 786: 783: 781: 778: 776: 773: 771: 768: 766: 763: 761: 758: 756: 753: 751: 748: 746: 743: 741: 738: 736: 733: 731: 728: 726: 723: 721: 718: 716: 713: 711: 708: 706: 703: 701: 698: 697: 695: 692: 691: 685: 682: 680: 677: 675: 672: 670: 667: 665: 662: 660: 657: 655: 652: 650: 647: 645: 642: 640: 637: 635: 632: 630: 627: 625: 622: 620: 617: 615: 612: 611: 609: 606: 605: 602: 601:Gene ontology 598: 594: 582: 577: 573: 566: 561: 558: 556: 552: 544: 539: 529:body of femur 528: 524: 520: 516: 512: 508: 504: 500: 496: 492: 491: 488: 484: 479: 476: 466: 463:apex of heart 462: 458: 454: 450: 446: 442: 438: 434: 430: 429: 426: 422: 417: 414: 413: 410: 408: 404: 402: 401: 397: 396: 393: 391: 387: 383: 379: 375: 367: 362: 358: 354: 349: 339: 335: 328: 321: 315: 308: 300: 296: 292: 287: 283: 278: 274: 266: 261: 257: 253: 248: 238: 234: 227: 220: 214: 207: 203: 197: 193: 189: 184: 180: 175: 171: 167: 163: 159: 155: 151: 147: 143: 139: 135: 131: 123: 118: 111: 106: 101: 90: 88: 84: 80: 76: 70: 65: 62: 61: 57: 54: 47: 43: 38: 34: 30: 25: 20: 5046: 5013:Ligand-gated 5004: 4992: 4835:Gap junction 4828: 4717: 4513: 4474: 4452: 4425: 4411: 4387: 4365: 4323: 4271: 4237: 4220: 4208: 4189: 4177: 4132: 4095: 4069: 3946: 3803: 3708: 3655: 3625: 3581: 3510: 3423: 3374: 3313: 3211: 3120: 3093: 3072: 3044: 3031: 3018: 2998: 2985: 2950: 2883:Ligand-gated 2868: 2851:ion channels 2802: 2787: 2772: 2757: 2697: 2696: 2685: 2679: 2671: 2629: 2625: 2596: 2593:Biochemistry 2592: 2556: 2552: 2515: 2511: 2476: 2472: 2454:(2): 371–7. 2451: 2447: 2412: 2408: 2377: 2373: 2339:(5): 435–8. 2336: 2332: 2305: 2301: 2270: 2266: 2217: 2213: 2168: 2164: 2139: 2135: 2108: 2077:(2): 68–72. 2074: 2070: 2037: 2033: 2008: 2004: 1959: 1955: 1926: 1881: 1877: 1867: 1830: 1826: 1816: 1781: 1777: 1767: 1735:(2): 92–96. 1732: 1728: 1718: 1709: 1700: 1691: 1682: 1597: 1582: 1570:sweat glands 1531: 1523: 1515: 1511: 1510: 1433: 1411:NP_001316801 1408: 1382: 1364:NM_001329872 1361: 1354:NM_001185062 1350:NM_001185061 1346:NM_001185060 1317: 1290: 1264: 1245: 1219: 1200: 1180: 1175: 770:brush border 525:human kidney 459:human kidney 405: 398: 125:External IDs 72: 5018:Light-gated 3500:IK channel 2740:PDB gallery 2661:Aquaporin+1 2333:Transfusion 1585:vasopressin 1562:endothelium 1560:, vascular 1542:basolateral 1512:Aquaporin 1 455:pericardium 364:55,325,540 351:55,313,417 263:30,925,517 250:30,911,853 103:Identifiers 5063:Categories 4221:Bestrophin 3479:SK channel 3447:BK channel 3121:γ-subunits 3094:β-subunits 3077:δ-subunits 2011:: 425–58. 1677:, May 2017 1656:, May 2017 1632:References 1599:Aquaporins 1576:, and the 1554:vasa recta 765:sarcolemma 493:right lung 439:right lung 409:(ortholog) 146:HomoloGene 5049:disorders 5047:see also 4830:Cytoplasm 4740:Aquaporin 4209:Anoctamin 4032:11.1/hERG 1621:Aquaporin 1436:NP_031498 1415:NP_932766 1385:NM_007472 1342:NM_000385 1338:NM_198098 1166:Orthologs 1121:transport 700:cytoplasm 517:left lung 154:GeneCards 4843:Connexin 4123:minK/ISK 2626:Genomics 2361:35893178 2156:16574458 2099:36525343 2091:11909995 2062:33398595 2054:11097616 2025:10872456 1918:11717407 1859:14561230 1808:31547764 1759:21119879 1673:– 1652:– 1615:See also 1594:Function 1484:Wikidata 1145:Sources: 715:membrane 4970:Innexin 4727:solutes 2646:7540589 2613:7532004 2583:7521882 2540:7521540 2520:Bibcode 2512:Science 2503:7518771 2460:7517253 2439:7514605 2430:2120064 2396:7507481 2353:3166547 2324:3049610 2289:2007592 2254:1722319 2222:Bibcode 2201:8550043 2193:1373524 2173:Bibcode 2165:Science 1996:7517546 1964:Bibcode 1886:Bibcode 1799:7045352 1750:2923372 1675:Ensembl 1654:Ensembl 1520:protein 1518:) is a 1278:UniProt 1233:Ensembl 1172:Species 1151:QuickGO 720:nucleus 384:pattern 110:Aliases 3267:-gated 3265:Proton 3041:T-type 3028:R-type 3015:Q-type 2995:P-type 2982:N-type 2947:L-type 2677:Human 2667:(MeSH) 2644:  2611:  2581:  2574:295159 2571:  2538:  2501:  2494:395186 2491:  2458:  2437:  2427:  2394:  2359:  2351:  2322:  2287:  2252:  2242:  2199:  2191:  2154:  2123:  2097:  2089:  2060:  2052:  2023:  1994:  1984:  1916:  1906:  1857:  1850:269983 1847:  1833:: 12. 1806:  1796:  1757:  1747:  1588:AVPR1A 1564:, the 1538:kidney 1470:search 1468:PubMed 1319:Q02013 1300:Q6JSD7 1296:Q6JSD8 1292:P29972 1188:Entrez 555:BioGPS 242:7p14.3 142:103201 134:107776 4881:GJA10 4732:Porin 4632:TRPML 4402:HVCN1 4096:KCNIP 3951:α7-12 2855:TC 1A 2357:S2CID 2245:53083 2197:S2CID 2095:S2CID 2058:S2CID 1987:44179 1909:64684 1574:lungs 1516:AQP-1 1221:11826 1181:Mouse 1176:Human 1147:Amigo 505:ankle 407:Mouse 400:Human 347:Start 282:Mouse 246:Start 179:Human 150:68051 4961:GJD4 4956:GJD3 4951:GJD2 4941:GJC3 4936:GJC2 4931:GJC1 4921:GJB7 4916:GJB6 4911:GJB5 4906:GJB4 4901:GJB3 4896:GJB2 4891:GJB1 4876:GJA9 4871:GJA8 4866:GJA5 4861:GJA4 4856:GJA3 4851:GJA1 4676:TRPV 4659:TRPP 4654:TRPN 4585:TRPM 4538:TRPC 4528:TRPA 4366:CLNS 4324:CLIC 4272:CLCN 4267:CFTR 4214:ANO1 4133:MiRP 4061:12.3 4056:12.2 4051:12.1 4042:11.3 4037:11.2 4023:10.2 4018:10.1 3808:α1-6 3622:GIRK 3036:α2.3 3023:α2.1 2990:α2.2 2803:1j4n 2788:1ih5 2773:1h6i 2758:1fqy 2686:AQP1 2680:AQP1 2642:PMID 2609:PMID 2579:PMID 2536:PMID 2499:PMID 2456:PMID 2435:PMID 2392:PMID 2349:PMID 2320:PMID 2285:PMID 2250:PMID 2189:PMID 2152:PMID 2121:ISBN 2087:PMID 2050:PMID 2021:PMID 1992:PMID 1914:PMID 1855:PMID 1804:PMID 1755:PMID 1527:gene 1524:AQP1 780:axon 390:Bgee 338:Band 299:Chr. 237:Band 196:Chr. 158:AQP1 130:OMIM 117:AQP1 87:1IH5 83:1H6I 79:1FQY 75:4CSK 56:RCSB 53:PDBe 22:AQP1 4725:(+ 4563:4AP 4476:HCN 4009:9.3 4004:9.2 3999:9.1 3990:8.2 3985:8.1 3976:7.5 3971:7.4 3966:7.3 3961:7.2 3956:7.1 3938:6.4 3933:6.3 3928:6.2 3923:6.1 3914:5.1 3905:4.3 3900:4.2 3895:4.1 3886:3.4 3881:3.3 3876:3.2 3871:3.1 3862:2.2 3857:2.1 3848:1.8 3843:1.7 3838:1.6 3833:1.5 3828:1.4 3823:1.3 3818:1.2 3813:1.1 3709:K2P 3689:7.1 3684:6.2 3679:6.1 3674:5.1 3669:4.2 3664:4.1 3649:3.4 3644:3.3 3639:3.2 3634:3.1 3615:2.6 3610:2.4 3605:2.3 3600:2.2 3595:2.1 3590:1.1 3576:ATP 3554:5.1 3549:4.2 3544:4.1 3539:3.1 3534:2.3 3529:2.2 3524:2.1 3519:1.1 3504:IK1 3494:SK3 3489:SK2 3484:SK1 3363:1.9 3358:1.8 3353:1.7 3348:1.6 3343:1.5 3338:1.4 3333:1.3 3328:1.2 3323:1.1 3212:Na: 3064:3.3 3059:3.2 3054:3.1 3008:2.1 2975:1.4 2970:1.3 2965:1.2 2960:1.1 2869:Ca: 2634:doi 2601:doi 2569:PMC 2561:doi 2528:doi 2516:265 2489:PMC 2481:doi 2425:PMC 2417:doi 2413:125 2382:doi 2378:269 2341:doi 2310:doi 2306:263 2275:doi 2271:266 2240:PMC 2230:doi 2181:doi 2169:256 2144:doi 2113:doi 2079:doi 2042:doi 2038:279 2013:doi 1982:PMC 1972:doi 1904:PMC 1894:doi 1845:PMC 1835:doi 1794:PMC 1786:doi 1745:PMC 1737:doi 1603:MIP 1202:358 521:rib 360:End 259:End 162:OMA 138:MGI 46:PDB 5065:: 4947:D 4927:C 4887:B 4847:A 4729:): 4482:FC 4376:1B 4371:1A 4359:L1 4317:KB 4312:KA 4191:Cl 3784:18 3779:17 3774:16 3769:15 3764:13 3759:12 3754:10 3658:ir 3628:ir 3584:ir 3513:Ca 3472:β4 3467:β3 3462:β2 3457:β1 3452:α1 3424:K: 3375:Na 3368:7A 3314:Na 3141:γ4 3136:γ3 3131:γ2 3126:γ1 3114:β4 3109:β3 3104:β2 3099:β1 3045:Ca 3032:Ca 3019:Ca 2999:Ca 2986:Ca 2951:Ca 2849:: 2640:. 2630:25 2628:. 2624:. 2607:. 2597:34 2595:. 2577:. 2567:. 2557:94 2555:. 2551:. 2534:. 2526:. 2514:. 2497:. 2487:. 2477:13 2475:. 2471:. 2452:32 2450:. 2433:. 2423:. 2411:. 2407:. 2390:. 2376:. 2372:. 2355:. 2347:. 2337:28 2335:. 2318:. 2304:. 2300:. 2283:. 2269:. 2265:. 2248:. 2238:. 2228:. 2218:88 2216:. 2212:. 2195:. 2187:. 2179:. 2167:. 2150:. 2140:13 2138:. 2119:. 2093:. 2085:. 2075:17 2073:. 2056:. 2048:. 2036:. 2019:. 2009:68 2007:. 1990:. 1980:. 1970:. 1960:91 1958:. 1954:. 1912:. 1902:. 1892:. 1882:98 1880:. 1876:. 1853:. 1843:. 1829:. 1825:. 1802:. 1792:. 1782:37 1780:. 1776:. 1753:. 1743:. 1731:. 1727:. 1708:. 1690:. 1661:^ 1640:^ 1580:. 1572:, 1568:, 1529:. 1149:/ 366:bp 353:bp 265:bp 252:bp 160:; 156:: 152:; 148:: 144:; 140:: 136:; 132:: 85:, 81:, 77:, 4832:: 4812:3 4807:2 4802:1 4790:9 4785:8 4780:7 4775:6 4770:5 4765:4 4760:3 4755:2 4750:1 4745:0 4723:O 4721:2 4719:H 4706:6 4701:5 4696:4 4691:3 4686:2 4681:1 4669:2 4664:1 4647:3 4642:2 4637:1 4625:8 4620:7 4615:6 4610:5 4605:4 4600:3 4595:2 4590:1 4578:7 4573:6 4568:5 4558:4 4553:3 4548:2 4543:1 4534:) 4532:1 4530:( 4517:: 4515:M 4502:4 4497:3 4492:2 4487:1 4468:3 4463:2 4458:1 4453:β 4446:4 4441:3 4436:2 4431:1 4426:α 4415:: 4413:M 4391:: 4389:H 4354:6 4349:5 4344:4 4339:3 4334:2 4329:1 4307:7 4302:6 4297:5 4292:4 4287:3 4282:2 4277:1 4258:4 4253:3 4248:2 4243:1 4231:2 4226:1 4193:: 4148:3 4143:2 4138:1 4116:4 4111:3 4106:2 4101:1 4089:3 4084:2 4079:1 4074:β 4072:v 4070:K 3949:v 3947:K 3806:v 3804:K 3749:9 3744:7 3739:6 3734:5 3729:4 3724:3 3719:2 3714:1 3656:K 3626:K 3624:/ 3582:K 3574:K 3511:K 3399:4 3394:3 3389:2 3384:1 3379:β 3377:v 3318:α 3316:v 3294:4 3289:3 3284:2 3279:1 3253:δ 3248:γ 3243:β 3238:α 3187:2 3182:1 3170:4 3165:3 3160:2 3155:1 3087:2 3082:1 3075:2 3073:α 3049:α 3047:v 3043:/ 3034:v 3030:/ 3021:v 3017:/ 3003:α 3001:v 2997:/ 2988:v 2984:/ 2955:α 2953:v 2949:/ 2927:3 2922:2 2917:1 2905:3 2900:2 2895:1 2857:) 2853:( 2839:e 2832:t 2825:v 2733:e 2726:t 2719:v 2706:. 2693:. 2648:. 2636:: 2615:. 2603:: 2585:. 2563:: 2542:. 2530:: 2522:: 2505:. 2483:: 2462:. 2441:. 2419:: 2398:. 2384:: 2363:. 2343:: 2326:. 2312:: 2291:. 2277:: 2256:. 2232:: 2224:: 2203:. 2183:: 2175:: 2158:. 2146:: 2129:. 2115:: 2101:. 2081:: 2064:. 2044:: 2027:. 2015:: 1998:. 1974:: 1966:: 1934:. 1920:. 1896:: 1888:: 1861:. 1837:: 1831:3 1810:. 1788:: 1761:. 1739:: 1733:8 1712:. 1694:. 1514:( 284:) 181:) 164::

Index


PDB
PDBe
RCSB
4CSK
1FQY
1H6I
1IH5
Aliases
AQP1
OMIM
107776
MGI
103201
HomoloGene
68051
GeneCards
AQP1
OMA
AQP1 - orthologs
Human
Chromosome 7 (human)
Chr.
Chromosome 7 (human)
Chromosome 7 (human)
Genomic location for AQP1
Genomic location for AQP1
Band
bp
bp

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