314:
291:
188:
213:
2752:
565:
572:
320:
219:
2797:
2767:
2782:
1610:
sites. The AQP1 monomer consists of six transmembrane alpha helices that are connected by five loops (A to E). The protein physically resembles channel proteins and is abundant in erythrocytes and renal tubes. The gene encoding this aquaporin is a possible candidate for disorders involving imbalance
29:
55:
1605:
or AQP0). This gene encodes an aquaporin which functions as both a molecular water channel protein and as a non-selective cation channel gated by cyclic guanosine monophosphate (cGMP). It is a homotetramer with six bilayer spanning domains and
2590:
van Hoek AN, Wiener MC, Verbavatz JM, Brown D, Lipniunas PH, Townsend RR, Verkman AS (February 1995). "Purification and structure-function analysis of native, PNGase F-treated, and endo-beta-galactosidase-treated CHIP28 water channels".
2106:
Mitra, Alok K.; Ren, Gang; Reddy, Vijay S.; Cheng, Anchi; Froger, Alexandrine (2008). "The
Architecture of a Water-Selective Pore in the Lipid Bilayer Visualized by Electron Crystallography in Vitreous Ice".
3621:
4531:
2134:
Ripoche P, Goossens D, Devuyst O, Gane P, Colin Y, Verkman AS, Cartron JP (2006). "Role of RhAG and AQP1 in NH3 and CO2 gas transport in red cell ghosts: a stopped-flow analysis".
4266:
3518:
3451:
2510:
Preston GM, Smith BL, Zeidel ML, Moulds JJ, Agre P (September 1994). "Mutations in aquaporin-1 in phenotypically normal humans without functional CHIP water channels".
327:
226:
2751:
2699:
1220:
149:
52:
1201:
4462:
4445:
4440:
4435:
4430:
4467:
3565:
2837:
2298:"Identification, purification, and partial characterization of a novel Mr 28,000 integral membrane protein from erythrocytes and renal tubules"
2163:
Preston GM, Carroll TP, Guggino WB, Agre P (April 1992). "Appearance of water channels in
Xenopus oocytes expressing red cell CHIP28 protein".
2731:
2124:
1705:
5068:
4519:
3700:
1687:
5073:
4417:
3438:
2854:
2331:
Zelinski T, Kaita H, Lewis M, Coghlan G, Philipps S, Belcher E, et al. (1988). "The Colton blood group locus. A linkage analysis".
313:
4203:
2678:
1452:
2796:
1459:
290:
2766:
1931:
4796:
3795:
3573:
2889:
1674:
1653:
4818:
1670:
212:
187:
5027:
2938:
2684:
1553:
2781:
1649:
4393:
3305:
2210:"Isolation of the cDNA for erythrocyte integral membrane protein of 28 kilodaltons: member of an ancient channel family"
129:
1823:"Single amino acids in the carboxyl terminal domain of aquaporin-1 contribute to cGMP-dependent ion channel activation"
4668:
2622:"Localization of the aquaporin 1 (AQP1) gene within a YAC contig containing the polymorphic markers D7S632 and D7S526"
326:
225:
2846:
2830:
5022:
3232:
2724:
319:
218:
2003:
Borgnia M, Nielsen S, Engel A, Agre P (2000). "Cellular and molecular biology of the aquaporin water channels".
5012:
3273:
3149:
2664:
2370:"Membrane topology of aquaporin CHIP. Analysis of functional epitope-scanning mutants by vectorial proteolysis"
1265:
137:
5017:
1246:
2263:"Erythrocyte Mr 28,000 transmembrane protein exists as a multisubunit oligomer similar to channel proteins"
5048:
3040:
3027:
3014:
2994:
2981:
2946:
1577:
1565:
2823:
1625:
2921:
2717:
2549:"Human red cell aquaporin CHIP. I. Molecular characterization of ABH and Colton blood group antigens"
2519:
2221:
2172:
1963:
1885:
1541:
201:
2069:
Yool AJ, Weinstein AM (April 2002). "New roles for old holes: ion channel function in aquaporin-1".
2815:
2690:
1410:
1363:
1353:
1349:
1345:
116:
4388:
3264:
2911:
2356:
2196:
2094:
2057:
161:
2405:"Biogenesis and transmembrane topology of the CHIP28 water channel at the endoplasmic reticulum"
1435:
1414:
1384:
1341:
1337:
3426:
2641:
2608:
2578:
2535:
2498:
2455:
2434:
2391:
2348:
2319:
2284:
2249:
2188:
2151:
2120:
2086:
2049:
2020:
1991:
1913:
1854:
1803:
1754:
109:
45:
4195:
3176:
2633:
2600:
2568:
2560:
2527:
2488:
2480:
2424:
2416:
2381:
2340:
2309:
2274:
2239:
2229:
2180:
2143:
2112:
2078:
2041:
2012:
1981:
1971:
1903:
1893:
1844:
1834:
1793:
1785:
1744:
1736:
564:
406:
337:
281:
236:
2344:
4731:
2871:
1607:
1557:
571:
381:
157:
2670:
1601:
are a family of small integral membrane proteins related to the major intrinsic protein (
921:
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
2523:
2225:
2176:
1967:
1889:
4527:
3214:
2660:
2620:
Keen TJ, Inglehearn CF, Patel RJ, Green ED, Peluso DC, Bhattacharya SS (January 1995).
2484:
2429:
2404:
1798:
1773:
1749:
1724:
2573:
2548:
2493:
2468:
2386:
2369:
2314:
2297:
2279:
2262:
1849:
1822:
1774:"Vasopressin V1a Receptors Regulate Cerebral Aquaporin 1 after Traumatic Brain Injury"
1135:
1130:
1125:
1120:
1115:
1110:
1105:
1100:
1095:
1090:
1085:
1080:
1075:
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1005:
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985:
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965:
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950:
945:
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935:
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920:
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905:
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865:
860:
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845:
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835:
830:
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815:
810:
794:
789:
784:
779:
774:
769:
764:
759:
754:
749:
744:
739:
734:
729:
724:
719:
714:
709:
704:
699:
683:
678:
673:
668:
663:
658:
653:
648:
643:
638:
633:
628:
623:
618:
613:
5062:
4481:
4154:
2703:
2637:
2244:
2209:
2045:
2016:
1986:
1951:
1908:
1873:
1549:
600:
2360:
2098:
2061:
4834:
4225:
2200:
1569:
399:
178:
141:
2184:
2147:
165:
4764:
4759:
4754:
4749:
4636:
4475:
2850:
2446:
Li X, Yu H, Koide SS (February 1994). "The water channel gene in human uterus".
1710:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1692:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1584:
1561:
2214:
Proceedings of the
National Academy of Sciences of the United States of America
1956:
Proceedings of the
National Academy of Sciences of the United States of America
1878:
Proceedings of the
National Academy of Sciences of the United States of America
1740:
482:
4744:
4110:
3478:
3446:
1602:
298:
195:
145:
2403:
Skach WR, Shi LB, Calayag MC, Frigeri A, Lingappa VR, Verkman AS (May 1994).
2234:
1536:, whose physiological function has been most thoroughly characterized in the
4829:
4739:
2531:
2082:
1976:
1620:
1598:
1533:
1165:
542:
420:
365:
352:
264:
251:
153:
2155:
2116:
2090:
2053:
2024:
1917:
1898:
1858:
1839:
1807:
1758:
2760:: STRUCTURE OF AQUAPORIN-1 AT 3.8 A RESOLUTION BY ELECTRON CRYSTALLOGRAPHY
2645:
2612:
2582:
2539:
2502:
2459:
2438:
2420:
2395:
2352:
2323:
2288:
2253:
2192:
1995:
1789:
1499:
1494:
4842:
4190:
3169:
3164:
3159:
3154:
3086:
3081:
2032:
Horster M (December 2000). "Embryonic epithelial membrane transporters".
1483:
1318:
1299:
1295:
1291:
2604:
4969:
4726:
4562:
3063:
3058:
3053:
1545:
1519:
1277:
1232:
2564:
2109:
Ion
Channels: From Atomic Resolution Physiology to Functional Genomics
86:
82:
78:
74:
4646:
4641:
4375:
4370:
4316:
4311:
4127:
4115:
4105:
4100:
4088:
4083:
4078:
3965:
3960:
3955:
3847:
3783:
3778:
3773:
3768:
3763:
3758:
3753:
3688:
3683:
3673:
3668:
3663:
3614:
3609:
3599:
3594:
3471:
3466:
3461:
3456:
3362:
3357:
3352:
3342:
3337:
3327:
3322:
3252:
3247:
3242:
3237:
3140:
3135:
3130:
3125:
3113:
3108:
3103:
3098:
3007:
2974:
2969:
2964:
2959:
2547:
Smith BL, Preston GM, Spring FA, Anstee DJ, Agre P (September 1994).
2469:"The three-dimensional structure of human erythrocyte aquaporin CHIP"
1874:"Dynamic mechanisms of the membrane water channel aquaporin-1 (AQP1)"
1587:
1537:
1467:
1187:
2621:
4880:
4811:
4806:
4801:
4718:
4705:
4700:
4695:
4690:
4685:
4680:
4631:
4624:
4619:
4614:
4609:
4604:
4599:
4594:
4589:
4577:
4572:
4567:
4557:
4552:
4547:
4542:
4457:
4401:
4358:
4353:
4348:
4343:
4338:
4333:
4328:
4306:
4301:
4296:
4291:
4286:
4281:
4276:
4257:
4252:
4247:
4242:
4230:
4147:
4142:
4137:
4122:
4060:
4055:
4050:
4041:
4036:
4022:
4017:
4008:
4003:
3998:
3989:
3984:
3975:
3970:
3937:
3932:
3927:
3922:
3913:
3904:
3899:
3894:
3885:
3880:
3875:
3870:
3861:
3856:
3842:
3837:
3832:
3827:
3822:
3817:
3812:
3748:
3743:
3738:
3733:
3728:
3723:
3718:
3713:
3678:
3648:
3643:
3638:
3633:
3604:
3553:
3548:
3543:
3538:
3528:
3523:
3503:
3488:
3483:
3398:
3393:
3388:
3383:
3367:
3347:
3332:
3293:
3288:
3283:
3278:
3186:
3181:
2904:
2899:
2894:
1573:
1772:
Rauen K, Pop V, Trabold R, Badaut J, Plesnila N (February 2020).
1150:
1146:
4960:
4955:
4950:
4940:
4935:
4930:
4920:
4915:
4910:
4905:
4900:
4895:
4890:
4875:
4870:
4865:
4860:
4855:
4850:
4789:
4784:
4779:
4774:
4769:
4675:
4663:
4658:
4653:
4584:
4537:
4501:
4496:
4491:
4486:
4213:
4031:
3589:
2926:
2916:
1526:
133:
4990:
4175:
3421:
3209:
2866:
2819:
2713:
28:
4514:
4412:
3533:
3493:
2709:
580:
1111:
metanephric proximal convoluted tubule segment 2 development
891:
establishment or maintenance of actin cytoskeleton polarity
2368:
Preston GM, Jung JS, Guggino WB, Agre P (January 1994).
2296:
Denker BM, Smith BL, Kuhajda FP, Agre P (October 1988).
389:
120:, AQP-CHIP, CHIP28, CO, aquaporin 1 (Colton blood group)
554:
1932:"Entrez Gene: AQP1 aquaporin 1 (Colton blood group)"
629:
intracellular cGMP-activated cation channel activity
5003:
4827:
4716:
4512:
4410:
4386:
4188:
3794:
3699:
3564:
3437:
3304:
3263:
3225:
2937:
2882:
1428:
1403:
1377:
1336:
1952:"The aquaporin family of molecular water channels"
1666:
1664:
1662:
1645:
1643:
1641:
644:carbon dioxide transmembrane transporter activity
336:
235:
2448:Biochemistry and Molecular Biology International
2111:. Novartis Foundation Symposia. pp. 33–50.
2034:American Journal of Physiology. Renal Physiology
1106:metanephric proximal straight tubule development
1026:positive regulation of epithelial cell migration
659:potassium ion transmembrane transporter activity
2467:Walz T, Smith BL, Agre P, Engel A (July 1994).
846:positive regulation of fibroblast proliferation
624:nitric oxide transmembrane transporter activity
16:Protein-coding gene in the species Homo sapiens
1671:GRCm38: Ensembl release 89: ENSMUSG00000004655
1116:metanephric glomerulus vasculature development
2831:
2805:: Crystal Structure of the AQP1 water channel
2725:
1021:positive regulation of lamellipodium assembly
8:
1101:metanephric descending thin limb development
1650:GRCh38: Ensembl release 89: ENSG00000240583
901:cellular response to dexamethasone stimulus
664:glycerol transmembrane transporter activity
619:ammonium transmembrane transporter activity
5000:
4987:
4185:
4172:
3434:
3418:
3222:
3206:
2879:
2863:
2838:
2824:
2816:
2775:: A REFINED STRUCTURE OF HUMAN AQUAPORIN 1
2732:
2718:
2710:
2700:United States National Library of Medicine
1333:
1161:
956:multicellular organismal water homeostasis
596:
377:
276:
173:
63:
2663:at the U.S. National Library of Medicine
2572:
2492:
2428:
2385:
2313:
2278:
2243:
2233:
1985:
1975:
1907:
1897:
1848:
1838:
1797:
1748:
2698:This article incorporates text from the
896:negative regulation of apoptotic process
876:cellular response to inorganic substance
816:cellular response to mechanical stimulus
654:water transmembrane transporter activity
2747:
1637:
1552:, and in the descending portion of the
946:positive regulation of saliva secretion
2345:10.1046/j.1537-2995.1988.28588337331.x
971:cellular response to hydrogen peroxide
841:carbon dioxide transmembrane transport
18:
2553:The Journal of Clinical Investigation
1051:positive regulation of cell migration
981:potassium ion transmembrane transport
750:integral component of plasma membrane
341:
302:
297:
240:
199:
194:
7:
2208:Preston GM, Agre P (December 1991).
710:symbiont-containing vacuole membrane
4204:Calcium-activated chloride channels
2374:The Journal of Biological Chemistry
2302:The Journal of Biological Chemistry
2267:The Journal of Biological Chemistry
1725:"Aquaporin and Blood Brain Barrier"
1723:Francesca, B.; Rezzani, R. (2010).
1544:and apical plasma membranes of the
906:positive regulation of angiogenesis
3274:Amiloride-sensitive cation channel
2790:: CRYSTAL STRUCTURE OF AQUAPORIN-1
2485:10.1002/j.1460-2075.1994.tb06597.x
2136:Transfusion Clinique et Biologique
1821:Boassa D, Yool AJ (October 2003).
1425:
1400:
1374:
1309:
1282:
1256:
1237:
1211:
1192:
811:cellular response to retinoic acid
639:transmembrane transporter activity
559:
513:choroid plexus of fourth ventricle
477:
415:
394:
14:
1556:. Additionally, it is found in
1522:that in humans is encoded by the
826:cellular response to nitric oxide
2795:
2780:
2765:
2750:
2672:Gallery of Aquaporin Simulations
2046:10.1152/ajprenal.2000.279.6.F982
2017:10.1146/annurev.biochem.68.1.425
986:ammonium transmembrane transport
926:cellular response to mercury ion
871:cellular response to salt stress
570:
563:
325:
318:
312:
289:
224:
217:
211:
186:
27:
4797:Voltage-dependent anion channel
2890:Inositol trisphosphate receptor
2261:Smith BL, Agre P (April 1991).
961:transepithelial water transport
821:cellular response to copper ion
4819:General bacterial porin family
2071:News in Physiological Sciences
1872:Kong Y, Ma J (December 2001).
1583:Neural AQP-1 are regulated by
1071:hyperosmotic salinity response
1061:secretory granule organization
991:cation transmembrane transport
936:cellular hyperosmotic response
730:integral component of membrane
581:More reference expression data
543:More reference expression data
1:
2387:10.1016/S0021-9258(17)42079-5
2315:10.1016/S0021-9258(19)37635-5
2280:10.1016/S0021-9258(18)38133-X
2005:Annual Review of Biochemistry
1548:, the descending limb of the
1086:camera-type eye morphogenesis
1041:lateral ventricle development
976:cerebrospinal fluid secretion
310:
209:
2638:10.1016/0888-7543(95)80070-3
2185:10.1126/science.256.5055.385
2148:10.1016/j.tracli.2006.03.004
1532:AQP-1 is a widely expressed
831:cellular response to hypoxia
5069:Genes on human chromosome 7
2409:The Journal of Cell Biology
1131:ion transmembrane transport
866:cellular response to stress
775:symbiont-containing vacuole
760:basolateral plasma membrane
5090:
5074:Integral membrane proteins
4238:Chloride Channel Accessory
2847:Membrane transport protein
2689:gene details page in the
1741:10.2174/157015910791233132
1611:in ocular fluid movement.
1036:sensory perception of pain
856:pancreatic juice secretion
634:potassium channel activity
5044:
4999:
4986:
4184:
4171:
3433:
3417:
3233:Epithelial sodium channel
3221:
3205:
2878:
2862:
2745:
1729:Current Neuropharmacology
1706:"Mouse PubMed Reference:"
1688:"Human PubMed Reference:"
1498:
1493:
1489:
1482:
1466:
1447:
1432:
1407:
1396:
1381:
1360:
1329:
1316:
1312:
1289:
1285:
1276:
1263:
1259:
1244:
1240:
1231:
1218:
1214:
1199:
1195:
1186:
1171:
1164:
1160:
1144:
861:cGMP biosynthetic process
836:cellular response to cAMP
679:identical protein binding
599:
595:
578:
562:
553:
540:
489:
480:
431:Descending thoracic aorta
427:
418:
388:
380:
376:
359:
346:
309:
288:
279:
275:
258:
245:
208:
185:
176:
172:
127:
124:
114:
107:
102:
71:
66:
49:
44:
39:
35:
26:
21:
3150:Cation channels of sperm
2665:Medical Subject Headings
2235:10.1073/pnas.88.24.11110
1950:Knepper MA (July 1994).
966:carbon dioxide transport
443:tendon of biceps brachii
2532:10.1126/science.7521540
2083:10.1152/nips.01372.2001
1977:10.1073/pnas.91.14.6255
1460:Chr 6: 55.31 – 55.33 Mb
1453:Chr 7: 30.91 – 30.93 Mb
1136:transmembrane transport
1126:cGMP-mediated signaling
1091:corticotropin secretion
1001:potassium ion transport
951:renal water homeostasis
886:cellular response to UV
881:cell volume homeostasis
674:ephrin receptor binding
447:upper lobe of left lung
2117:10.1002/0470868759.ch4
1899:10.1073/pnas.251507998
1840:10.1186/1472-6793-3-12
1778:Journal of Neurotrauma
1578:central nervous system
1566:gastrointestinal tract
1540:. It is found in the
1096:renal water absorption
931:nitric oxide transport
725:apical plasma membrane
669:water channel activity
3226:Constitutively active
2421:10.1083/jcb.125.4.803
1790:10.1089/neu.2019.6653
1626:Colton antigen system
1011:hyperosmotic response
996:glomerular filtration
941:bicarbonate transport
916:renal water transport
795:extracellular exosome
755:brush border membrane
745:basal plasma membrane
451:right coronary artery
2683:genome location and
1076:response to estrogen
851:cellular homeostasis
614:transporter activity
343:6 B3|6 27.38 cM
304:Chromosome 6 (mouse)
202:Chromosome 7 (human)
67:List of PDB id codes
40:Available structures
4993:By gating mechanism
2691:UCSC Genome Browser
2605:10.1021/bi00007a015
2524:1994Sci...265.1585P
2226:1991PNAS...8811110P
2177:1992Sci...256..385P
1968:1994PNAS...91.6255K
1890:2001PNAS...9814345K
1590:receptor activity.
1016:response to hormone
740:apical part of cell
4520:TRP cation channel
4418:CNG cation channel
3701:Tandem pore domain
2912:Ryanodine receptor
2702:, which is in the
1266:ENSMUSG00000004655
1031:glycerol transport
804:Biological process
693:Cellular component
607:Molecular function
501:tibiofemoral joint
467:lower lobe of lung
5056:
5055:
5040:
5039:
5036:
5035:
5028:Stretch-activated
5005:Ion channel class
4982:
4981:
4978:
4977:
4167:
4166:
4163:
4162:
3439:Calcium-activated
3427:Potassium channel
3413:
3412:
3409:
3408:
3201:
3200:
3197:
3196:
2813:
2812:
2565:10.1172/JCI117418
2126:978-0-470-84375-8
1509:
1508:
1505:
1504:
1478:
1477:
1443:
1442:
1422:
1421:
1392:
1391:
1371:
1370:
1325:
1324:
1306:
1305:
1272:
1271:
1253:
1252:
1227:
1226:
1208:
1207:
1156:
1155:
1056:secretion by cell
1046:water homeostasis
785:neuron projection
591:
590:
587:
586:
549:
548:
536:
535:
474:
473:
372:
371:
271:
270:
98:
97:
94:
93:
50:Ortholog search:
5081:
5001:
4988:
4196:Chloride channel
4186:
4173:
3566:Inward-rectifier
3435:
3419:
3223:
3207:
3177:Two-pore channel
2880:
2864:
2840:
2833:
2826:
2817:
2799:
2784:
2769:
2754:
2734:
2727:
2720:
2711:
2649:
2616:
2586:
2576:
2543:
2518:(5178): 1585–7.
2506:
2496:
2473:The EMBO Journal
2463:
2442:
2432:
2399:
2389:
2364:
2327:
2317:
2308:(30): 15634–42.
2292:
2282:
2257:
2247:
2237:
2204:
2159:
2130:
2102:
2065:
2028:
1999:
1989:
1979:
1936:
1935:
1928:
1922:
1921:
1911:
1901:
1869:
1863:
1862:
1852:
1842:
1818:
1812:
1811:
1801:
1769:
1763:
1762:
1752:
1720:
1714:
1713:
1702:
1696:
1695:
1684:
1678:
1668:
1657:
1647:
1546:proximal tubules
1491:
1490:
1462:
1455:
1438:
1426:
1417:
1401:
1397:RefSeq (protein)
1387:
1375:
1366:
1334:
1310:
1283:
1257:
1238:
1212:
1193:
1162:
705:nuclear membrane
684:channel activity
597:
583:
574:
567:
560:
545:
509:fourth ventricle
485:
483:Top expressed in
478:
423:
421:Top expressed in
416:
395:
378:
368:
355:
344:
329:
322:
316:
305:
293:
277:
267:
254:
243:
228:
221:
215:
204:
190:
174:
168:
166:AQP1 - orthologs
119:
112:
89:
64:
58:
37:
36:
31:
19:
5089:
5088:
5084:
5083:
5082:
5080:
5079:
5078:
5059:
5058:
5057:
5052:
5032:
4995:
4974:
4823:
4722:
4712:
4508:
4406:
4382:
4180:
4159:
4073:
3950:
3807:
3790:
3695:
3659:
3629:
3585:
3577:
3560:
3514:
3429:
3405:
3378:
3317:
3300:
3259:
3217:
3193:
3076:
3048:
3035:
3022:
3002:
2989:
2954:
2933:
2874:
2872:Calcium channel
2858:
2844:
2814:
2809:
2806:
2800:
2791:
2785:
2776:
2770:
2761:
2755:
2741:
2738:
2657:
2652:
2619:
2589:
2546:
2509:
2479:(13): 2985–93.
2466:
2445:
2402:
2367:
2330:
2295:
2273:(10): 6407–15.
2260:
2220:(24): 11110–4.
2207:
2171:(5055): 385–7.
2162:
2142:(1–2): 117–22.
2133:
2127:
2105:
2068:
2031:
2002:
1949:
1945:
1943:Further reading
1940:
1939:
1930:
1929:
1925:
1884:(25): 14345–9.
1871:
1870:
1866:
1820:
1819:
1815:
1771:
1770:
1766:
1722:
1721:
1717:
1704:
1703:
1699:
1686:
1685:
1681:
1669:
1660:
1648:
1639:
1634:
1617:
1608:N-glycosylation
1596:
1558:red blood cells
1500:View/Edit Mouse
1495:View/Edit Human
1458:
1451:
1448:Location (UCSC)
1434:
1413:
1409:
1383:
1362:
1356:
1352:
1348:
1344:
1340:
1298:
1294:
1247:ENSG00000240583
1140:
1081:lipid digestion
1006:water transport
799:
735:plasma membrane
688:
649:protein binding
579:
569:
568:
541:
532:
527:
523:
519:
515:
511:
507:
503:
499:
497:right lung lobe
495:
481:
470:
465:
461:
457:
453:
449:
445:
441:
437:
435:ascending aorta
433:
419:
363:
350:
342:
332:
331:
330:
323:
303:
280:Gene location (
262:
249:
241:
231:
230:
229:
222:
200:
177:Gene location (
128:
115:
108:
73:
51:
17:
12:
11:
5:
5087:
5085:
5077:
5076:
5071:
5061:
5060:
5054:
5053:
5045:
5042:
5041:
5038:
5037:
5034:
5033:
5031:
5030:
5025:
5020:
5015:
5009:
5007:
4997:
4996:
4991:
4984:
4983:
4980:
4979:
4976:
4975:
4973:
4972:
4967:
4966:
4965:
4964:
4963:
4958:
4953:
4945:
4944:
4943:
4938:
4933:
4925:
4924:
4923:
4918:
4913:
4908:
4903:
4898:
4893:
4885:
4884:
4883:
4878:
4873:
4868:
4863:
4858:
4853:
4839:
4837:
4825:
4824:
4822:
4821:
4816:
4815:
4814:
4809:
4804:
4794:
4793:
4792:
4787:
4782:
4777:
4772:
4767:
4762:
4757:
4752:
4747:
4736:
4734:
4720:
4714:
4713:
4711:
4710:
4709:
4708:
4703:
4698:
4693:
4688:
4683:
4673:
4672:
4671:
4666:
4656:
4651:
4650:
4649:
4644:
4639:
4629:
4628:
4627:
4622:
4617:
4612:
4607:
4602:
4597:
4592:
4582:
4581:
4580:
4575:
4570:
4565:
4560:
4555:
4550:
4545:
4535:
4524:
4522:
4510:
4509:
4507:
4506:
4505:
4504:
4499:
4494:
4489:
4484:
4472:
4471:
4470:
4465:
4460:
4450:
4449:
4448:
4443:
4438:
4433:
4422:
4420:
4408:
4407:
4405:
4404:
4398:
4396:
4394:Proton channel
4384:
4383:
4381:
4380:
4379:
4378:
4373:
4363:
4362:
4361:
4356:
4351:
4346:
4341:
4336:
4331:
4321:
4320:
4319:
4314:
4309:
4304:
4299:
4294:
4289:
4284:
4279:
4269:
4264:
4263:
4262:
4261:
4260:
4255:
4250:
4245:
4235:
4234:
4233:
4228:
4218:
4217:
4216:
4200:
4198:
4182:
4181:
4176:
4169:
4168:
4165:
4164:
4161:
4160:
4158:
4157:
4152:
4151:
4150:
4145:
4140:
4130:
4125:
4120:
4119:
4118:
4113:
4108:
4103:
4093:
4092:
4091:
4086:
4081:
4071:
4066:
4065:
4064:
4063:
4058:
4053:
4046:
4045:
4044:
4039:
4034:
4027:
4026:
4025:
4020:
4013:
4012:
4011:
4006:
4001:
3994:
3993:
3992:
3987:
3980:
3979:
3978:
3973:
3968:
3963:
3958:
3948:
3943:
3942:
3941:
3940:
3935:
3930:
3925:
3918:
3917:
3916:
3909:
3908:
3907:
3902:
3897:
3890:
3889:
3888:
3883:
3878:
3873:
3866:
3865:
3864:
3859:
3852:
3851:
3850:
3845:
3840:
3835:
3830:
3825:
3820:
3815:
3805:
3800:
3798:
3792:
3791:
3789:
3788:
3787:
3786:
3781:
3776:
3771:
3766:
3761:
3756:
3751:
3746:
3741:
3736:
3731:
3726:
3721:
3716:
3705:
3703:
3697:
3696:
3694:
3693:
3692:
3691:
3686:
3681:
3676:
3671:
3666:
3657:
3653:
3652:
3651:
3646:
3641:
3636:
3627:
3619:
3618:
3617:
3612:
3607:
3602:
3597:
3592:
3583:
3579:
3575:
3570:
3568:
3562:
3561:
3559:
3558:
3557:
3556:
3551:
3546:
3541:
3536:
3531:
3526:
3521:
3512:
3508:
3507:
3506:
3498:
3497:
3496:
3491:
3486:
3476:
3475:
3474:
3469:
3464:
3459:
3454:
3443:
3441:
3431:
3430:
3422:
3415:
3414:
3411:
3410:
3407:
3406:
3404:
3403:
3402:
3401:
3396:
3391:
3386:
3376:
3372:
3371:
3370:
3365:
3360:
3355:
3350:
3345:
3340:
3335:
3330:
3325:
3315:
3310:
3308:
3302:
3301:
3299:
3298:
3297:
3296:
3291:
3286:
3281:
3270:
3268:
3261:
3260:
3258:
3257:
3256:
3255:
3250:
3245:
3240:
3229:
3227:
3219:
3218:
3215:Sodium channel
3210:
3203:
3202:
3199:
3198:
3195:
3194:
3192:
3191:
3190:
3189:
3184:
3174:
3173:
3172:
3167:
3162:
3157:
3146:
3145:
3144:
3143:
3138:
3133:
3128:
3118:
3117:
3116:
3111:
3106:
3101:
3091:
3090:
3089:
3084:
3074:
3069:
3068:
3067:
3066:
3061:
3056:
3046:
3038:
3033:
3025:
3020:
3012:
3011:
3010:
3000:
2992:
2987:
2979:
2978:
2977:
2972:
2967:
2962:
2952:
2943:
2941:
2935:
2934:
2932:
2931:
2930:
2929:
2924:
2919:
2909:
2908:
2907:
2902:
2897:
2886:
2884:
2876:
2875:
2867:
2860:
2859:
2845:
2843:
2842:
2835:
2828:
2820:
2811:
2810:
2808:
2807:
2801:
2794:
2792:
2786:
2779:
2777:
2771:
2764:
2762:
2756:
2749:
2746:
2743:
2742:
2739:
2737:
2736:
2729:
2722:
2714:
2695:
2694:
2675:
2668:
2656:
2655:External links
2653:
2651:
2650:
2632:(2): 599–600.
2617:
2587:
2544:
2507:
2464:
2443:
2400:
2380:(3): 1668–73.
2365:
2328:
2293:
2258:
2205:
2160:
2131:
2125:
2103:
2066:
2040:(6): F982-96.
2029:
2000:
1962:(14): 6255–8.
1946:
1944:
1941:
1938:
1937:
1923:
1864:
1827:BMC Physiology
1813:
1784:(4): 665–674.
1764:
1715:
1697:
1679:
1658:
1636:
1635:
1633:
1630:
1629:
1628:
1623:
1616:
1613:
1595:
1592:
1507:
1506:
1503:
1502:
1497:
1487:
1486:
1480:
1479:
1476:
1475:
1473:
1471:
1464:
1463:
1456:
1449:
1445:
1444:
1441:
1440:
1430:
1429:
1423:
1420:
1419:
1405:
1404:
1398:
1394:
1393:
1390:
1389:
1379:
1378:
1372:
1369:
1368:
1358:
1357:
1331:
1327:
1326:
1323:
1322:
1314:
1313:
1307:
1304:
1303:
1287:
1286:
1280:
1274:
1273:
1270:
1269:
1261:
1260:
1254:
1251:
1250:
1242:
1241:
1235:
1229:
1228:
1225:
1224:
1216:
1215:
1209:
1206:
1205:
1197:
1196:
1190:
1184:
1183:
1178:
1173:
1169:
1168:
1158:
1157:
1154:
1153:
1142:
1141:
1139:
1138:
1133:
1128:
1123:
1118:
1113:
1108:
1103:
1098:
1093:
1088:
1083:
1078:
1073:
1068:
1063:
1058:
1053:
1048:
1043:
1038:
1033:
1028:
1023:
1018:
1013:
1008:
1003:
998:
993:
988:
983:
978:
973:
968:
963:
958:
953:
948:
943:
938:
933:
928:
923:
918:
913:
908:
903:
898:
893:
888:
883:
878:
873:
868:
863:
858:
853:
848:
843:
838:
833:
828:
823:
818:
813:
807:
805:
801:
800:
798:
797:
792:
787:
782:
777:
772:
767:
762:
757:
752:
747:
742:
737:
732:
727:
722:
717:
712:
707:
702:
696:
694:
690:
689:
687:
686:
681:
676:
671:
666:
661:
656:
651:
646:
641:
636:
631:
626:
621:
616:
610:
608:
604:
603:
593:
592:
589:
588:
585:
584:
576:
575:
557:
551:
550:
547:
546:
538:
537:
534:
533:
531:
530:
526:
522:
518:
514:
510:
506:
502:
498:
494:
490:
487:
486:
475:
472:
471:
469:
468:
464:
460:
456:
452:
448:
444:
440:
436:
432:
428:
425:
424:
412:
411:
403:
392:
386:
385:
382:RNA expression
374:
373:
370:
369:
361:
357:
356:
348:
345:
340:
334:
333:
324:
317:
311:
307:
306:
301:
295:
294:
286:
285:
273:
272:
269:
268:
260:
256:
255:
247:
244:
239:
233:
232:
223:
216:
210:
206:
205:
198:
192:
191:
183:
182:
170:
169:
126:
122:
121:
113:
105:
104:
100:
99:
96:
95:
92:
91:
69:
68:
60:
59:
48:
42:
41:
33:
32:
24:
23:
15:
13:
10:
9:
6:
4:
3:
2:
5086:
5075:
5072:
5070:
5067:
5066:
5064:
5051:
5050:
5043:
5029:
5026:
5024:
5023:Voltage-gated
5021:
5019:
5016:
5014:
5011:
5010:
5008:
5006:
5002:
4998:
4994:
4989:
4985:
4971:
4968:
4962:
4959:
4957:
4954:
4952:
4949:
4948:
4946:
4942:
4939:
4937:
4934:
4932:
4929:
4928:
4926:
4922:
4919:
4917:
4914:
4912:
4909:
4907:
4904:
4902:
4899:
4897:
4894:
4892:
4889:
4888:
4886:
4882:
4879:
4877:
4874:
4872:
4869:
4867:
4864:
4862:
4859:
4857:
4854:
4852:
4849:
4848:
4846:
4845:
4844:
4841:
4840:
4838:
4836:
4833:
4831:
4826:
4820:
4817:
4813:
4810:
4808:
4805:
4803:
4800:
4799:
4798:
4795:
4791:
4788:
4786:
4783:
4781:
4778:
4776:
4773:
4771:
4768:
4766:
4763:
4761:
4758:
4756:
4753:
4751:
4748:
4746:
4743:
4742:
4741:
4738:
4737:
4735:
4733:
4730:
4728:
4724:
4715:
4707:
4704:
4702:
4699:
4697:
4694:
4692:
4689:
4687:
4684:
4682:
4679:
4678:
4677:
4674:
4670:
4667:
4665:
4662:
4661:
4660:
4657:
4655:
4652:
4648:
4645:
4643:
4640:
4638:
4635:
4634:
4633:
4630:
4626:
4623:
4621:
4618:
4616:
4613:
4611:
4608:
4606:
4603:
4601:
4598:
4596:
4593:
4591:
4588:
4587:
4586:
4583:
4579:
4576:
4574:
4571:
4569:
4566:
4564:
4561:
4559:
4556:
4554:
4551:
4549:
4546:
4544:
4541:
4540:
4539:
4536:
4533:
4529:
4526:
4525:
4523:
4521:
4518:
4516:
4511:
4503:
4500:
4498:
4495:
4493:
4490:
4488:
4485:
4483:
4480:
4479:
4478:
4477:
4473:
4469:
4466:
4464:
4461:
4459:
4456:
4455:
4454:
4451:
4447:
4444:
4442:
4439:
4437:
4434:
4432:
4429:
4428:
4427:
4424:
4423:
4421:
4419:
4416:
4414:
4409:
4403:
4400:
4399:
4397:
4395:
4392:
4390:
4385:
4377:
4374:
4372:
4369:
4368:
4367:
4364:
4360:
4357:
4355:
4352:
4350:
4347:
4345:
4342:
4340:
4337:
4335:
4332:
4330:
4327:
4326:
4325:
4322:
4318:
4315:
4313:
4310:
4308:
4305:
4303:
4300:
4298:
4295:
4293:
4290:
4288:
4285:
4283:
4280:
4278:
4275:
4274:
4273:
4270:
4268:
4265:
4259:
4256:
4254:
4251:
4249:
4246:
4244:
4241:
4240:
4239:
4236:
4232:
4229:
4227:
4224:
4223:
4222:
4219:
4215:
4212:
4211:
4210:
4207:
4206:
4205:
4202:
4201:
4199:
4197:
4194:
4192:
4187:
4183:
4179:
4178:Miscellaneous
4174:
4170:
4156:
4155:Shaker (gene)
4153:
4149:
4146:
4144:
4141:
4139:
4136:
4135:
4134:
4131:
4129:
4128:minK/ISK-like
4126:
4124:
4121:
4117:
4114:
4112:
4109:
4107:
4104:
4102:
4099:
4098:
4097:
4094:
4090:
4087:
4085:
4082:
4080:
4077:
4076:
4075:
4068:
4067:
4062:
4059:
4057:
4054:
4052:
4049:
4048:
4047:
4043:
4040:
4038:
4035:
4033:
4030:
4029:
4028:
4024:
4021:
4019:
4016:
4015:
4014:
4010:
4007:
4005:
4002:
4000:
3997:
3996:
3995:
3991:
3988:
3986:
3983:
3982:
3981:
3977:
3974:
3972:
3969:
3967:
3964:
3962:
3959:
3957:
3954:
3953:
3952:
3945:
3944:
3939:
3936:
3934:
3931:
3929:
3926:
3924:
3921:
3920:
3919:
3915:
3912:
3911:
3910:
3906:
3903:
3901:
3898:
3896:
3893:
3892:
3891:
3887:
3884:
3882:
3879:
3877:
3874:
3872:
3869:
3868:
3867:
3863:
3860:
3858:
3855:
3854:
3853:
3849:
3846:
3844:
3841:
3839:
3836:
3834:
3831:
3829:
3826:
3824:
3821:
3819:
3816:
3814:
3811:
3810:
3809:
3802:
3801:
3799:
3797:
3796:Voltage-gated
3793:
3785:
3782:
3780:
3777:
3775:
3772:
3770:
3767:
3765:
3762:
3760:
3757:
3755:
3752:
3750:
3747:
3745:
3742:
3740:
3737:
3735:
3732:
3730:
3727:
3725:
3722:
3720:
3717:
3715:
3712:
3711:
3710:
3707:
3706:
3704:
3702:
3698:
3690:
3687:
3685:
3682:
3680:
3677:
3675:
3672:
3670:
3667:
3665:
3662:
3661:
3660:
3654:
3650:
3647:
3645:
3642:
3640:
3637:
3635:
3632:
3631:
3630:
3623:
3620:
3616:
3613:
3611:
3608:
3606:
3603:
3601:
3598:
3596:
3593:
3591:
3588:
3587:
3586:
3580:
3578:
3572:
3571:
3569:
3567:
3563:
3555:
3552:
3550:
3547:
3545:
3542:
3540:
3537:
3535:
3532:
3530:
3527:
3525:
3522:
3520:
3517:
3516:
3515:
3509:
3505:
3502:
3501:
3499:
3495:
3492:
3490:
3487:
3485:
3482:
3481:
3480:
3477:
3473:
3470:
3468:
3465:
3463:
3460:
3458:
3455:
3453:
3450:
3449:
3448:
3445:
3444:
3442:
3440:
3436:
3432:
3428:
3425:
3420:
3416:
3400:
3397:
3395:
3392:
3390:
3387:
3385:
3382:
3381:
3380:
3373:
3369:
3366:
3364:
3361:
3359:
3356:
3354:
3351:
3349:
3346:
3344:
3341:
3339:
3336:
3334:
3331:
3329:
3326:
3324:
3321:
3320:
3319:
3312:
3311:
3309:
3307:
3306:Voltage-gated
3303:
3295:
3292:
3290:
3287:
3285:
3282:
3280:
3277:
3276:
3275:
3272:
3271:
3269:
3266:
3262:
3254:
3251:
3249:
3246:
3244:
3241:
3239:
3236:
3235:
3234:
3231:
3230:
3228:
3224:
3220:
3216:
3213:
3208:
3204:
3188:
3185:
3183:
3180:
3179:
3178:
3175:
3171:
3168:
3166:
3163:
3161:
3158:
3156:
3153:
3152:
3151:
3148:
3147:
3142:
3139:
3137:
3134:
3132:
3129:
3127:
3124:
3123:
3122:
3119:
3115:
3112:
3110:
3107:
3105:
3102:
3100:
3097:
3096:
3095:
3092:
3088:
3085:
3083:
3080:
3079:
3078:
3071:
3070:
3065:
3062:
3060:
3057:
3055:
3052:
3051:
3050:
3042:
3039:
3037:
3029:
3026:
3024:
3016:
3013:
3009:
3006:
3005:
3004:
2996:
2993:
2991:
2983:
2980:
2976:
2973:
2971:
2968:
2966:
2963:
2961:
2958:
2957:
2956:
2948:
2945:
2944:
2942:
2940:
2939:Voltage-gated
2936:
2928:
2925:
2923:
2920:
2918:
2915:
2914:
2913:
2910:
2906:
2903:
2901:
2898:
2896:
2893:
2892:
2891:
2888:
2887:
2885:
2881:
2877:
2873:
2870:
2865:
2861:
2856:
2852:
2848:
2841:
2836:
2834:
2829:
2827:
2822:
2821:
2818:
2804:
2798:
2793:
2789:
2783:
2778:
2774:
2768:
2763:
2759:
2753:
2748:
2744:
2735:
2730:
2728:
2723:
2721:
2716:
2715:
2712:
2708:
2707:
2705:
2704:public domain
2701:
2692:
2688:
2687:
2682:
2681:
2676:
2674:
2673:
2669:
2666:
2662:
2659:
2658:
2654:
2647:
2643:
2639:
2635:
2631:
2627:
2623:
2618:
2614:
2610:
2606:
2602:
2599:(7): 2212–9.
2598:
2594:
2588:
2584:
2580:
2575:
2570:
2566:
2562:
2559:(3): 1043–9.
2558:
2554:
2550:
2545:
2541:
2537:
2533:
2529:
2525:
2521:
2517:
2513:
2508:
2504:
2500:
2495:
2490:
2486:
2482:
2478:
2474:
2470:
2465:
2461:
2457:
2453:
2449:
2444:
2440:
2436:
2431:
2426:
2422:
2418:
2415:(4): 803–15.
2414:
2410:
2406:
2401:
2397:
2393:
2388:
2383:
2379:
2375:
2371:
2366:
2362:
2358:
2354:
2350:
2346:
2342:
2338:
2334:
2329:
2325:
2321:
2316:
2311:
2307:
2303:
2299:
2294:
2290:
2286:
2281:
2276:
2272:
2268:
2264:
2259:
2255:
2251:
2246:
2241:
2236:
2231:
2227:
2223:
2219:
2215:
2211:
2206:
2202:
2198:
2194:
2190:
2186:
2182:
2178:
2174:
2170:
2166:
2161:
2157:
2153:
2149:
2145:
2141:
2137:
2132:
2128:
2122:
2118:
2114:
2110:
2104:
2100:
2096:
2092:
2088:
2084:
2080:
2076:
2072:
2067:
2063:
2059:
2055:
2051:
2047:
2043:
2039:
2035:
2030:
2026:
2022:
2018:
2014:
2010:
2006:
2001:
1997:
1993:
1988:
1983:
1978:
1973:
1969:
1965:
1961:
1957:
1953:
1948:
1947:
1942:
1933:
1927:
1924:
1919:
1915:
1910:
1905:
1900:
1895:
1891:
1887:
1883:
1879:
1875:
1868:
1865:
1860:
1856:
1851:
1846:
1841:
1836:
1832:
1828:
1824:
1817:
1814:
1809:
1805:
1800:
1795:
1791:
1787:
1783:
1779:
1775:
1768:
1765:
1760:
1756:
1751:
1746:
1742:
1738:
1734:
1730:
1726:
1719:
1716:
1711:
1707:
1701:
1698:
1693:
1689:
1683:
1680:
1676:
1672:
1667:
1665:
1663:
1659:
1655:
1651:
1646:
1644:
1642:
1638:
1631:
1627:
1624:
1622:
1619:
1618:
1614:
1612:
1609:
1604:
1600:
1593:
1591:
1589:
1586:
1581:
1579:
1575:
1571:
1567:
1563:
1559:
1555:
1551:
1550:loop of Henle
1547:
1543:
1539:
1535:
1534:water channel
1530:
1528:
1525:
1521:
1517:
1513:
1501:
1496:
1492:
1488:
1485:
1481:
1474:
1472:
1469:
1465:
1461:
1457:
1454:
1450:
1446:
1439:
1437:
1431:
1427:
1424:
1418:
1416:
1412:
1406:
1402:
1399:
1395:
1388:
1386:
1380:
1376:
1373:
1367:
1365:
1359:
1355:
1351:
1347:
1343:
1339:
1335:
1332:
1330:RefSeq (mRNA)
1328:
1321:
1320:
1315:
1311:
1308:
1302:
1301:
1297:
1293:
1288:
1284:
1281:
1279:
1275:
1268:
1267:
1262:
1258:
1255:
1249:
1248:
1243:
1239:
1236:
1234:
1230:
1223:
1222:
1217:
1213:
1210:
1204:
1203:
1198:
1194:
1191:
1189:
1185:
1182:
1179:
1177:
1174:
1170:
1167:
1163:
1159:
1152:
1148:
1143:
1137:
1134:
1132:
1129:
1127:
1124:
1122:
1119:
1117:
1114:
1112:
1109:
1107:
1104:
1102:
1099:
1097:
1094:
1092:
1089:
1087:
1084:
1082:
1079:
1077:
1074:
1072:
1069:
1067:
1066:wound healing
1064:
1062:
1059:
1057:
1054:
1052:
1049:
1047:
1044:
1042:
1039:
1037:
1034:
1032:
1029:
1027:
1024:
1022:
1019:
1017:
1014:
1012:
1009:
1007:
1004:
1002:
999:
997:
994:
992:
989:
987:
984:
982:
979:
977:
974:
972:
969:
967:
964:
962:
959:
957:
954:
952:
949:
947:
944:
942:
939:
937:
934:
932:
929:
927:
924:
922:
919:
917:
914:
912:
911:odontogenesis
909:
907:
904:
902:
899:
897:
894:
892:
889:
887:
884:
882:
879:
877:
874:
872:
869:
867:
864:
862:
859:
857:
854:
852:
849:
847:
844:
842:
839:
837:
834:
832:
829:
827:
824:
822:
819:
817:
814:
812:
809:
808:
806:
803:
802:
796:
793:
791:
790:axon terminus
788:
786:
783:
781:
778:
776:
773:
771:
768:
766:
763:
761:
758:
756:
753:
751:
748:
746:
743:
741:
738:
736:
733:
731:
728:
726:
723:
721:
718:
716:
713:
711:
708:
706:
703:
701:
698:
697:
695:
692:
691:
685:
682:
680:
677:
675:
672:
670:
667:
665:
662:
660:
657:
655:
652:
650:
647:
645:
642:
640:
637:
635:
632:
630:
627:
625:
622:
620:
617:
615:
612:
611:
609:
606:
605:
602:
601:Gene ontology
598:
594:
582:
577:
573:
566:
561:
558:
556:
552:
544:
539:
529:body of femur
528:
524:
520:
516:
512:
508:
504:
500:
496:
492:
491:
488:
484:
479:
476:
466:
463:apex of heart
462:
458:
454:
450:
446:
442:
438:
434:
430:
429:
426:
422:
417:
414:
413:
410:
408:
404:
402:
401:
397:
396:
393:
391:
387:
383:
379:
375:
367:
362:
358:
354:
349:
339:
335:
328:
321:
315:
308:
300:
296:
292:
287:
283:
278:
274:
266:
261:
257:
253:
248:
238:
234:
227:
220:
214:
207:
203:
197:
193:
189:
184:
180:
175:
171:
167:
163:
159:
155:
151:
147:
143:
139:
135:
131:
123:
118:
111:
106:
101:
90:
88:
84:
80:
76:
70:
65:
62:
61:
57:
54:
47:
43:
38:
34:
30:
25:
20:
5046:
5013:Ligand-gated
5004:
4992:
4835:Gap junction
4828:
4717:
4513:
4474:
4452:
4425:
4411:
4387:
4365:
4323:
4271:
4237:
4220:
4208:
4189:
4177:
4132:
4095:
4069:
3946:
3803:
3708:
3655:
3625:
3581:
3510:
3423:
3374:
3313:
3211:
3120:
3093:
3072:
3044:
3031:
3018:
2998:
2985:
2950:
2883:Ligand-gated
2868:
2851:ion channels
2802:
2787:
2772:
2757:
2697:
2696:
2685:
2679:
2671:
2629:
2625:
2596:
2593:Biochemistry
2592:
2556:
2552:
2515:
2511:
2476:
2472:
2454:(2): 371–7.
2451:
2447:
2412:
2408:
2377:
2373:
2339:(5): 435–8.
2336:
2332:
2305:
2301:
2270:
2266:
2217:
2213:
2168:
2164:
2139:
2135:
2108:
2077:(2): 68–72.
2074:
2070:
2037:
2033:
2008:
2004:
1959:
1955:
1926:
1881:
1877:
1867:
1830:
1826:
1816:
1781:
1777:
1767:
1735:(2): 92–96.
1732:
1728:
1718:
1709:
1700:
1691:
1682:
1597:
1582:
1570:sweat glands
1531:
1523:
1515:
1511:
1510:
1433:
1411:NP_001316801
1408:
1382:
1364:NM_001329872
1361:
1354:NM_001185062
1350:NM_001185061
1346:NM_001185060
1317:
1290:
1264:
1245:
1219:
1200:
1180:
1175:
770:brush border
525:human kidney
459:human kidney
405:
398:
125:External IDs
72:
5018:Light-gated
3500:IK channel
2740:PDB gallery
2661:Aquaporin+1
2333:Transfusion
1585:vasopressin
1562:endothelium
1560:, vascular
1542:basolateral
1512:Aquaporin 1
455:pericardium
364:55,325,540
351:55,313,417
263:30,925,517
250:30,911,853
103:Identifiers
5063:Categories
4221:Bestrophin
3479:SK channel
3447:BK channel
3121:γ-subunits
3094:β-subunits
3077:δ-subunits
2011:: 425–58.
1677:, May 2017
1656:, May 2017
1632:References
1599:Aquaporins
1576:, and the
1554:vasa recta
765:sarcolemma
493:right lung
439:right lung
409:(ortholog)
146:HomoloGene
5049:disorders
5047:see also
4830:Cytoplasm
4740:Aquaporin
4209:Anoctamin
4032:11.1/hERG
1621:Aquaporin
1436:NP_031498
1415:NP_932766
1385:NM_007472
1342:NM_000385
1338:NM_198098
1166:Orthologs
1121:transport
700:cytoplasm
517:left lung
154:GeneCards
4843:Connexin
4123:minK/ISK
2626:Genomics
2361:35893178
2156:16574458
2099:36525343
2091:11909995
2062:33398595
2054:11097616
2025:10872456
1918:11717407
1859:14561230
1808:31547764
1759:21119879
1673:–
1652:–
1615:See also
1594:Function
1484:Wikidata
1145:Sources:
715:membrane
4970:Innexin
4727:solutes
2646:7540589
2613:7532004
2583:7521882
2540:7521540
2520:Bibcode
2512:Science
2503:7518771
2460:7517253
2439:7514605
2430:2120064
2396:7507481
2353:3166547
2324:3049610
2289:2007592
2254:1722319
2222:Bibcode
2201:8550043
2193:1373524
2173:Bibcode
2165:Science
1996:7517546
1964:Bibcode
1886:Bibcode
1799:7045352
1750:2923372
1675:Ensembl
1654:Ensembl
1520:protein
1518:) is a
1278:UniProt
1233:Ensembl
1172:Species
1151:QuickGO
720:nucleus
384:pattern
110:Aliases
3267:-gated
3265:Proton
3041:T-type
3028:R-type
3015:Q-type
2995:P-type
2982:N-type
2947:L-type
2677:Human
2667:(MeSH)
2644:
2611:
2581:
2574:295159
2571:
2538:
2501:
2494:395186
2491:
2458:
2437:
2427:
2394:
2359:
2351:
2322:
2287:
2252:
2242:
2199:
2191:
2154:
2123:
2097:
2089:
2060:
2052:
2023:
1994:
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1857:
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1296:Q6JSD8
1292:P29972
1188:Entrez
555:BioGPS
242:7p14.3
142:103201
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2245:53083
2197:S2CID
2095:S2CID
2058:S2CID
1987:44179
1909:64684
1574:lungs
1516:AQP-1
1221:11826
1181:Mouse
1176:Human
1147:Amigo
505:ankle
407:Mouse
400:Human
347:Start
282:Mouse
246:Start
179:Human
150:68051
4961:GJD4
4956:GJD3
4951:GJD2
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4851:GJA1
4676:TRPV
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4654:TRPN
4585:TRPM
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4324:CLIC
4272:CLCN
4267:CFTR
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4133:MiRP
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4056:12.2
4051:12.1
4042:11.3
4037:11.2
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3036:α2.3
3023:α2.1
2990:α2.2
2803:1j4n
2788:1ih5
2773:1h6i
2758:1fqy
2686:AQP1
2680:AQP1
2642:PMID
2609:PMID
2579:PMID
2536:PMID
2499:PMID
2456:PMID
2435:PMID
2392:PMID
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2250:PMID
2189:PMID
2152:PMID
2121:ISBN
2087:PMID
2050:PMID
2021:PMID
1992:PMID
1914:PMID
1855:PMID
1804:PMID
1755:PMID
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780:axon
390:Bgee
338:Band
299:Chr.
237:Band
196:Chr.
158:AQP1
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