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InChI=1S/C24H34O4/c1-22-10-7-17(25)13-16(22)4-5-20-19(22)8-11-23(2)18(9-12-24(20,23)27)15-3-6-21(26)28-14-15/h3,6,14,16-20,25,27H,4-5,7-13H2,1-2H3/t16-,17+,18-,19+,20-,22+,23-,24+/m1/s1
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A Dasgupta, P Datta (1998). "Rapid detection of cardioactive bufalin toxicity using fluorescence polarization immunoassay for digitoxin".
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Wu SH (2014). "Bufalin induces cell death in human lung cancer cells through disruption of DNA damage response pathways".
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600:"Pharmacology of the principles isolated from Senso (Ch'an Su) the dried venom of the Chinese toad (IV)"
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628:"Bufalin attenuates the stage and metastatic potential of hepatocellular carcinoma in nude mice"
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Ma H (Jul 2012). "The novel antidote Bezoar Bovis prevents the cardiotoxicity of Toad (
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Except where otherwise noted, data are given for materials in their
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Okada, Masahiro; Suga, Toshiro; et al. (April 1960).
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513:antitumor effects against various malignant
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525:, its potential use is hampered by its
491:toxin originally isolated from Chinese
307:C12CC(C1CC32CC4(3(CC4c5ccc(=O)oc5)O)C)O
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40:3β,14-Dihydroxy-5β-bufa-20,22-dienolide
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286:Key: QEEBRPGZBVVINN-BMPKRDENSA-N
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7:
517:, including hepatocellular and lung
582:"Datasheet: Bufotalin sc-sc-200136"
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587:. Santa Cruz Biotechnology, Inc.
560:10.1097/00007691-199802000-00019
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495:, which is a component of some
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425:Precautionary statements
716:Canto) Venom in mice".
645:10.1186/1479-5876-12-57
714:Bufo bufo gargarizans
626:Zhang ZJ (Feb 2014).
608:Asian Medical Journal
51:4-phenanthren-1-yl]-2
47:Systematic IUPAC name
358: g·mol
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763:Cardiac stimulants
718:Exp Toxicol Pathol
470:Infobox references
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478:Chemical compound
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411:Hazard statements
239:CompTox Dashboard
103:Interactive image
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554:(1): 104–108.
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507:Bufalin has
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143:ChEMBL399680
123:CHEBI:517248
62:Identifiers
55:-pyran-2-one
52:
758:Bufanolides
486:cardiotonic
397:Signal word
316:Properties
181:100.150.073
752:Categories
533:References
515:cell lines
493:toad venom
381:Pictograms
351:Molar mass
227:U549S98QLW
154:ChemSpider
90:3D model (
69:CAS Number
37:IUPAC name
519:carcinoma
439:P301+P310
372:labelling
738:21084181
699:24871662
664:24581171
510:in vitro
503:Research
363:Hazards
79:465-21-4
17:Bufalin
655:4015709
568:9485564
489:steroid
482:Bufalin
356:386.532
207:9547215
194:PubChem
163:7826155
768:Toxins
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662:
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638:: 57.
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403:Danger
300:SMILES
134:ChEMBL
31:Names
603:(PDF)
585:(PDF)
484:is a
275:InChI
114:ChEBI
92:JSmol
734:PMID
695:PMID
660:PMID
564:PMID
455:P501
451:P405
447:P330
443:P321
435:P270
431:P264
417:H300
218:UNII
726:doi
687:doi
650:PMC
640:doi
556:doi
370:GHS
244:EPA
197:CID
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613:3
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558::
344:4
341:O
335:H
329:C
246:)
242:(
94:)
53:H
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