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Bell's mania

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37: 664: 804:, paranoia and increase in body temperature. In 1934, Stauder described a series of acute onset of psychomotor agitation in young people with no history of physical or psychological disturbances. He termed this description as Lethal Catatonia. Other reasons for the manifestation of Bell's Mania, points at the use of stimulant drugs in excessive amounts and also psychiatric diseases like 755: 407: 624: 197:, which impedes the apprehension of this syndrome.  Hence at present, there is still no scientific consensus on the clinical features of Bell's mania. Researchers are currently working on varying case studies to derive common clinical characteristics. Some frequent signs and symptoms include acute onset of 1773:
Cipriani, Andrea; Barbui, Corrado; Salanti, Georgia; Rendell, Jennifer; Brown, Rachel; Stockton, Sarah; Purgato, Marianna; Spineli, Loukia M; Goodwin, Guy M; Geddes, John R (October 2011). "Comparative efficacy and acceptability of antimanic drugs in acute mania: a multiple-treatments meta-analysis".
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The first case of Bell's Mania was observed by medical examiners during the cocaine epidemic in countries like the United States of America and Canada with some other cases being related to police brutality and restraint. The term Bell's Mania was first coined to describe the clinical condition with
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and sudden death in individuals with cocaine addiction. Since the law enforcement were often called to contain violent behavior exhibited by these individuals, it was speculated that police brutality might be the underlying cause of the deaths. Upon medical review of the cases related to the use of
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In 1985, Bell's Mania was first mentioned in a definitive manner using the term Excited Delirium (EXD). Prior to that year, most cases of death by cocaine intoxication during the cocaine epidemic that happened in a sudden manner. This involved the exposure to highly toxic amounts of the drug due to
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correction. Although more research is needed in correspondence to the cause and consequences of this disease, the significance of the behavioral and physical symptoms need to be given importance to provide medical institutions as well the constabulary the necessary information to respond to Bell's
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Bell, Luther V. (October 1849). "On a Form of Disease resembling some advanced stages of mania and fever, but so contradistinguished from any ordinarily observed or described combination of symptoms, as to render it probable that it may be an overlooked and hitherto unrecorded malady: by Luther V.
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When examined, patients with Bell's mania fail to recall names, recent experiences and are poorly oriented for location, date, and time. Moreover, their blood pressure and respiratory rate are increased. Additionally, mental status examination using questionnaires and three diagnostic tests are
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Amplified excitation of the dopaminergic systems can induce extreme fear and magnify both approach and avoidance behaviors. The hyperdopaminergic state triggers aggression, agitation and psychomotor excitement. Additionally, CNS dopamine signaling is active in heart rate, respiration and body
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Bell's mania and catatonia are regarded as "overlapping syndromes", making differential diagnosis essential when catatonic signs are observed. Thus, researchers must distinguish between excited catatonia and Bell's mania, and among malignant catatonia, excited catatonia, and
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respectively. Diagnostic complications arise as these signs are also often the notable feature of Bell's mania. With the cause undetermined, Bell's mania diagnosis is usually justified with the presence of both mania and delirium regardless of the catatonic symptoms.
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Although adult data on the use of Ketamine on patients isn't readily available, a study by Strayer et al. concluded that the use of ketamine for controlling the hyperactivity was reliable and can further facilitate other management techniques with fewer side effects.
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injections have been discussed for medical professionals and individuals with the condition. Bell's mania cases are commonly reported in countries like the United States and Canada and are commonly associated with psychostimulant use and abuse.
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Nevertheless, a formal set of diagnostic criteria is required to distinguish between Bell's mania and catatonia. Failure to diagnose Bell's mania appearing as catatonia could lead to deleterious consequences and, in worse cases, death.
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Psychostimulant users and abusers, patients with drug withdrawal, undiagnosed/untreated psychiatric patients, people with severe manic episodes, sleep deprived individuals, people with medical history of neurological and physiological
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and ultimately death. In light of the clinical findings, some treatments have been described which include effective sedation, followed closely by external cooling, monitoring medical complications and the administration of
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Vilke, Gary M.; DeBard, Mark L.; Chan, Theodore C.; Ho, Jeffrey D.; Dawes, Donald M.; Hall, Christine; Curtis, Michael D.; Costello, Melissa Wysong; Mash, Deborah C.; Coffman, Stewart R.; McMullen, Mary Jo (November 2012).
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One management technique is rapid sedation in view of the unpredictable aggressive nature of the patient with Bell's Mania, especially if the symptoms that need to be handled are associated with the causes like
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Over the course of time the significance of this syndrome has been increasingly recognized in correspondence to the manner of death, specifically because the anatomic cause of death is hard to define during
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The suggestive symptoms of this disorder were first observed in the 19th century, out of which some of the most significant ones are the onset of aggression, bizarre behavior, violence, excessive shouting,
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Cordeiro, Catarina R.; Saraiva, Rodrigo; Côrte-Real, Beatriz; Pestana, Pedro Câmara; Andrade, Gabriela; Fernandes, Elsa; Castanheira, LÃ-gia; Martins, and Paulo (2020-04-09).
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The urgency and medical severity of the condition needs to be given impetus in terms of handling patients with Bell's Mania. Due to the homologous nature of this syndrome with
348:(NMS). When catatonic features are prominent, it is diagnosed as excited catatonia and when absent or subtle, it is identified as Bell's mania. Alternatively, the presence of 500:
Dopaminergic transporters dysfunction is caused by acute mania of bipolar disorder, psychostimulant use, and environmental stress. It is suggested to be common mechanism in
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Dysfunction of dopaminergic transporters, anomalous activation of the dorsal anterior cingulate, right inferior frontal cortical regions, excited hyperdopaminergic mechanism
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Dopamine transporter regulates the reuptake of dopamine to keep the synaptic dopamine levels within normal range. Hence, the elevation of such transporter levels in the
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the bursting of cocaine packets being carried within the body by "body stuffers". In the same year a series of observations were made by Welti and Fishbain regarding
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Green, Steven M; Rothrock, Steven G; Lynch, Elizabeth L; Ho, Matthew; Harris, Troy; Hestdalen, Rodney; Hopkins, G.Alan; Garrett, Wayne; Westcott, Kelli (June 1998).
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Whilst the scope of Bell's Mania is extensively studied, there remain some significant challenges that need to be solved with respect to treatment and management.
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are susceptible.  Furthermore, this syndrome is usually precipitated from prevailing neurological and physiological conditions. Hence, those at risk include
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Hyperactivity, hyperthermia, delirium, disruption in psychomotor activities, emotional liability, fear, panic, aggression, violence, sensory dysfunction, death
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decreases neurotransmission. Genetic studies have hypothesized a relationship between low transporter protein levels and the gene for dopamine transporter in
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is recognized as the discerning factor. A difference between the two is that catatonia is viewed from a movement aspect, whereas delirium from consciousness.
306:. Patients with Bell's mania tend to make obvious mistakes in these tests, for instance drawing a clock-face with incorrect numbering or missing clock hands. 775:
in the 1850s after observing institutionalized psychiatric patients. The first clinical reports and descriptions of people with acute exhaustive mania and
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can help. Several studies also point at the increased effectiveness of combination of two or more sedatives in the treatment of hyper agitated patients.
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Manic symptoms exacerbate with increasing anterior cingulate activation, which is posited to be associated with escalating dopamine transmission in the
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Battaglia, John; Moss, Sue; Rush, John; Kang, Jasbir; Mendoza, Ricardo; Leedom, Liane; Dubin, William; McGlynn, Charles; Goodman, Lowell (July 1997).
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injections are alternative solutions that have been proposed. With an onset time of 30 seconds to 4 minutes ketamine proves to be more effective than
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users as well as individuals experiencing severe manic episodes are more prone to the manifestation of this condition. Management solutions such as
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Upon acute onset of the symptoms, an instant investigation for a toxic or systemic cause is undertaken. Prominence of thought disorder,
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a 75% mortality rate. The prevalence of this condition ranges from 15% to 25% in the society and, is not an infrequent occurrence.
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levels in the victims. Emergency personnel need to recognize these symptoms promptly to avoid the individual from spiraling into
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Richter, Diethelm W.; Mironov, Sergej L.; Büsselberg, Dietrich; Lalley, Peter M.; Bischoff, Anne M.; Wilken, Bernd (June 2000).
2279:"Haloperidol, lorazepam, or both for psychotic agitation? A multicenter, prospective, double-blind, emergency department study" 697:
Along with sedation techniques, a few other prevention and protection measures can decrease fatal outcomes, some of which are:
1091:"Fatal Excited Delirium Following Cocaine Use: Epidemiologic Findings Provide New Evidence for Mechanisms of Cocaine Toxicity" 345: 101:
Rapid sedation, intramuscular ketamine injections, electroconvulsive therapy, blood tests, regulation of body temperature.
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Ruttenber, A. James; Lawler-Heavner, Janet; Yin, Ming; Wetli, Charles V.; Hearn, W. Lee; Mash, Deborah C. (1997-01-01).
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batons, pepper sprays and restraint methods did not disclose any autonomic cause behind the death, albeit problems like
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and Bell's mania. Hence, studying bipolar patients can provide insight into the pathophysiology of this Bell's mania.
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Patients with Bell's mania may not have optimum time for the sedatives to start showing effect. Due to this fact,
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Ashok, A. H.; Marques, T. R.; Jauhar, S.; Nour, M. M.; Goodwin, G. M.; Young, A. H.; Howes, O. D. (May 2017).
1189:"Excited Delirium and Sudden Death: A Syndromal Disorder at the Extreme End of the Neuropsychiatric Continuum" 2224:"A Double-Blind Study of Lorazepam versus the Combination of Haloperidol and Lorazepam in Managing Agitation" 2552: 1819:"The dopamine hypothesis of bipolar affective disorder: the state of the art and implications for treatment" 631: 1931:"Time course of extracellular dopamine and behavioral sensitization to cocaine. I. Dopamine axon terminals" 1540: 2326:"Intramuscular Ketamine for Pediatric Sedation in the Emergency Department: Safety Profile in 1,022 Cases" 826: 88: 44:
The hypothesized cause of Bell's mania is said to be abnormally elevated levels of extracellular dopamine.
2898: 485: 396: 194: 124:, refers to an acute neurobehavioral syndrome. This is usually characterized by an expeditious onset of 2670:
Pollanen, Michael S; Smith, Charles R; Chiasson, David A; Cairns, James T; Young, James (April 2002).
1416: 492:. This phenomenon is not distinct to drug abuse but also other psychomotor stimulants such as stress. 273:
This condition is currently not recognized as a diagnosable issue by psychiatric journals such as the
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neurotransmitters in the brain. It helps in bringing extreme agitation and catatonia under control.
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Bell, M. D., Physician and Superintendent of the McLean Asylum for the Insane, Somerville, Mass".
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The use of Intramuscular Ketamine Injections is a popular method in the treatment of Bell's Mania.
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is postulated to be the underlying mechanism of Bell's Mania, people prone to dopamine imbalance,
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are additional symptoms that follow. There are shifts from having loud and disorganized speech to
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are a type of tranquilizers used in the treatment of Bell's Mania that take effect by acting on
612: 604: 481: 214: 141: 59: 1591:"Delirious Mania: Can We Get Away with This Concept? A Case Report and Review of the Literature" 2222:
Bieniek, Sherrie A.; Ownby, Raymond L.; Penalver, Alberto; Dominguez, Roberto A. (1998-01-02).
2877: 2837: 2798: 2790: 2746: 2738: 2699: 2691: 2644: 2605: 2597: 2578:"Factors associated with sudden death of individuals requiring restraint for excited delirium" 2526: 2518: 2447: 2439: 2400: 2392: 2353: 2345: 2306: 2298: 2251: 2243: 2204: 2196: 2149: 2110: 2070: 2062: 2015: 2007: 1968: 1950: 1903: 1895: 1856: 1838: 1791: 1755: 1747: 1705: 1697: 1659: 1622: 1568: 1560: 1490: 1444: 1436: 1385: 1342: 1334: 1290: 1272: 1228: 1210: 1118: 1110: 1068: 1060: 1014: 996: 908: 900: 805: 480:
like cocaine. These substances provoke behavioral changes similar to mania. In chronic users,
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occurs which induces increased neurotransmission and modified protein expression within the
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Patients who are drug withdrawal states or are non-compliant with psychotropic drugs  
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Melamed, Eitan; Oron, Yahav; Ben-Avraham, Ron; Blumenfeld, Amir; Lin, Guy (October 2007).
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symptoms and other signs, including fluctuations in body temperatures and fear. Increased
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Stratton, Samuel J.; Rogers, Christopher; Brickett, Karen; Gruzinski, Ginger (May 2001).
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were provided by a few psychiatrists in the United States of America, France and the
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due to the presence of overlapping symptoms. Pathophysiology studies reveal elevated
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dopamine neurons. Adaptations in dopamine transporters is further triggered causing
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are often present. Impaired concentration, memory loss, disorientation, insomnia,
2474:"Neuroleptic Malignant Syndrome: A Rare, Dangerous Effect of Antipsychotic Drugs" 2435: 2003: 2372: 2091:"Excited Delirium Syndrome (ExDS): Defining Based on a Review of the Literature" 758:
Luther Vose Bell (1806-1862) was the first person to coin the term Bell's Mania.
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International Statistical Classification of Diseases and Related Health Problems
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Penders, Thomas M.; Gestring, Richard E.; Vilensky, Dmitry A. (November 2012).
1686:"The face-hand test: a useful addition to the psychiatric physical examination" 1875: 1432: 895: 878: 729: 707: 238: 226: 106: 2881: 2794: 2742: 2695: 2648: 2601: 2577: 2522: 2443: 2396: 2349: 2302: 2247: 2200: 2153: 2066: 2011: 1954: 1899: 1842: 1751: 1701: 1564: 1440: 1338: 1276: 1214: 1205: 1114: 1064: 1000: 904: 2817: 2593: 1267: 817: 754: 552: 427: 384: 331: 234: 222: 206: 169: 157: 133: 2703: 2609: 2530: 2451: 2404: 2373:"Adverse events associated with ketamine for procedural sedation in adults" 2208: 2114: 2058: 2019: 1860: 1795: 1759: 1685: 1626: 1572: 1494: 1448: 1346: 1313:
JACOBOWSKI, NATALIE L.; HECKERS, STEPHAN; BOBO, WILLIAM V. (January 2013).
1294: 1232: 1018: 912: 299: 2841: 2818:"Cocaine-Induced Psychosis and Sudden Death in Recreational Cocaine Users" 2802: 2750: 2420:"The combative multitrauma patient: a protocol for prehospital management" 2357: 2310: 2255: 2176: 1972: 1907: 1709: 1607: 1249:
Lee, Bo-Shyan; Huang, Si-Sheng; Hsu, Wen-Yu; Chiu, Nan-Ying (2012-06-21).
1122: 1072: 1041:"Cocaine-Induced Psychosis and Sudden Death in Recreational Cocaine Users" 410:
Sagittal cross-section of the brain illustrating the dopaminergic pathway.
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dopamine levels can be caused by low levels of dopaminergic transporters,
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Benzodiazepines, antipsychotic medication, ketamine injections, dantrolene
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People with medical history of neurological and physiological conditions
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Sleep deprivation which can trigger and even worsen acute manic episodes
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Takeuchi, Asia; Ahern, Terence L.; Henderson, Sean O. (February 2011).
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Silverstone, Trevor; Wells, Brian; Trenchard, Esther (February 1983).
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Bobo, William V.; Murphy, Michael J.; Heckers, Stephan H. (May 2009).
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cascade and rapidly sedating the patient using several sedatives like
2553:"The Crack Epidemic - The History of Crack Cocaine - Drug-Free World" 595:. Recent studies have elicited neurochemical imbalances resulting in 277:
by the American Psychiatric Association or the tenth revision of the
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Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy
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Seitz, Dallas P.; Gill, Sudeep S.; van Zyl, Louis T. (2007-01-15).
1728:"Figure-Ground Discrimination After Induced Altered Brain Function" 936: 879:"Recurring episodes of Bell's mania after cerebrovascular accident" 1415:
Karmacharya, Rakesh; England, Mary Lou; Öngür, Dost (2008-08-01).
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temperature regulation. Dopamine imbalance can hence result in
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The majority of Bell's mania cases studied are triggered by
1417:"Delirious mania: Clinical features and treatment response" 93:
Bipolar disorder, acute schizophrenia, catatonia, delirium
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of manic patients illustrate anomalous activation of the
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Diagnostic and Statistical Manual of Mental Disorders-IV
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The American Journal of Forensic Medicine and Pathology
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KAHN, ROBERT L.; POLLACK, MAX; FINK, MAX (1960-05-01).
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and trauma was excluded from the extensive evaluation.
322:, and catatonic signs indicates the diagnosis of acute 2717:
Fishbain, David A.; Wetli, Charles V. (October 1981).
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Strayer, Reuben J.; Nelson, Lewis S. (November 2008).
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is also a probable treatment route owing to its swift
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Wetli, Charles V.; Fishbain, David A. (1985-07-01).
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Wetli, Charles V.; Fishbain, David A. (1985-07-01).
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Sensitization of postsynaptic dopaminergic receptors
771:which was first explained by American psychiatrist 383:are postulated to be responsible for the manic and 105: 97: 87: 76: 68: 58: 48: 26: 21: 1589:Bipeta, Rajshekhar; Khan, Majeed A. (2012-11-12). 472:External sources contributing to the hypothesized 375:of Bell's mania. Elevated dopamine levels in the 339:Distinguishing between Bell's mania and catatonia 249:.  Some typical physiological signs include 1690:Psychiatric Journal of the University of Ottawa 1684:Patten, S. B.; Lamarre, C. J. (November 1989). 2499:"Cocaine-excited delirium and severe acidosis" 1992:The American Journal of Drug and Alcohol Abuse 2177:"Antipsychotics in the Treatment of Delirium" 704:basic medical monitoring of bodily functions, 8: 2629:Archiv für Psychiatrie und Nervenkrankheiten 2041:Mann, S. C.; Boger, W. P. (September 1978). 1650:, Abingdon, UK: Taylor & Francis, 2003, 1475:The Primary Care Companion for CNS Disorders 767:Bell's Mania is a syndrome with unexplained 1374:Encyclopedia of Forensic and Legal Medicine 561:Undiagnosed/ untreated psychiatric patients 2582:The American Journal of Emergency Medicine 2377:The American Journal of Emergency Medicine 2283:The American Journal of Emergency Medicine 35: 18: 2672:"Fatal child abuse-maltreatment syndrome" 1962: 1850: 1616: 1606: 1284: 1266: 1222: 1204: 1008: 894: 1648:Quick Cognitive Screening for Clinicians 753: 662: 622: 436:right inferior frontal cortical regions. 405: 860: 415:Role of genetics and signaling pathways 2497:Allam, S.; Noble, J. S. (April 2001). 2424:European Journal of Emergency Medicine 1638: 1636: 1584: 1582: 1534: 1532: 1410: 1408: 1406: 1182: 1180: 1178: 1176: 1174: 1172: 1170: 1168: 1166: 1164: 1162: 1160: 1158: 1156: 1154: 1152: 978: 976: 974: 716:rapid cooling of the body temperature. 2764: 2762: 2760: 1721: 1719: 1530: 1528: 1526: 1524: 1522: 1520: 1518: 1516: 1514: 1512: 1464: 1462: 1460: 1458: 1244: 1242: 1150: 1148: 1146: 1144: 1142: 1140: 1138: 1136: 1134: 1132: 1084: 1082: 1034: 1032: 1030: 1028: 989:Western Journal of Emergency Medicine 972: 970: 968: 966: 964: 962: 960: 958: 956: 954: 496:Dopaminergic transporters dysfunction 217:. They tend to be excited, agitated, 193:drug usage or preexisting medical or 7: 1929:Kalivas, PW; Duffy, P (1993-01-01). 1744:10.1001/archneur.1960.03840110061007 1308: 1306: 1304: 872: 870: 868: 866: 864: 795:First Appearance of Related Symptoms 726:neuroleptic malignant syndrome (NMS) 701:management of catecholamine cascade, 2515:10.1046/j.1365-2044.2001.01976-24.x 397:postsynaptic dopaminergic receptors 338: 2240:10.1002/j.1875-9114.1998.tb03827.x 2181:The Journal of Clinical Psychiatry 1947:10.1523/jneurosci.13-01-00266.1993 1331:10.1097/01.pra.0000426324.67322.06 243:auditory and visual hallucinations 14: 2095:The Journal of Emergency Medicine 672:Intramuscular Ketamine Injections 648:regulation. Turning off the 2787:10.1097/00000433-198703000-00001 2769:Wetli, Charles V. (March 1987). 2623:Stauder, K. H. (December 1934). 2557:Foundation for a Drug-Free World 1557:10.1034/j.1399-5618.1999.10112.x 528:and sleep disturbance symptoms. 54:Behavioral neurology, psychiatry 1656:10.4324/9780203427170_chapter_4 1319:Journal of Psychiatric Practice 422:is a prominent symptom of both 2862:American Journal of Psychiatry 2676:Forensic Science International 2107:10.1016/j.jemermed.2011.02.017 2047:American Journal of Psychiatry 1421:Journal of Affective Disorders 1382:10.1016/b0-12-369399-3/00311-6 1376:, Elsevier, pp. 276–281, 599:hyperactivity and increase in 346:neuroleptic malignant syndrome 1: 2735:10.1016/s0196-0644(81)80010-8 2688:10.1016/s0379-0738(02)00008-7 2342:10.1016/s0196-0644(98)70226-4 2295:10.1016/s0735-6757(97)90119-4 1788:10.1016/S0140-6736(11)60873-8 763:First mention of Bell's Mania 168:as the underlying mechanism. 2822:Journal of Forensic Sciences 2771:"Fatal Cocaine Intoxication" 2723:Annals of Emergency Medicine 2436:10.1097/mej.0b013e32823a3c9b 2330:Annals of Emergency Medicine 2004:10.3109/00952990.2012.694535 1095:Journal of Forensic Sciences 1045:Journal of Forensic Sciences 457:Stimulant elicited responses 1935:The Journal of Neuroscience 722:malignant hyperthermia (MH) 693:Other Preventative Measures 2920: 2389:10.1016/j.ajem.2007.12.005 2146:10.1177/107385840000600309 1595:Case Reports in Psychiatry 465: 451:bipolar affective patients 381:neuropsychiatric disorders 1433:10.1016/j.jad.2007.12.001 1187:Mash, Deborah C. (2016). 928:Emergency Medical Service 896:10.1176/appi.psy.50.3.285 678:electroconvulsive therapy 432:dorsal anterior cingulate 283:World Health Organization 43: 34: 2625:"Die tödliche Katatonie" 1644:"The Clock Drawing Test" 1206:10.3389/fphys.2016.00435 822:cardiorespiratory arrest 713:physical examination and 578:Treatment and Management 490:behavioral sensitization 225:such as grimacing, 2594:10.1053/ajem.2001.22665 1268:10.1186/1471-244X-12-65 1193:Frontiers in Physiology 618:intravenous (IV) fluids 538:hyperdopaminergic state 195:neurological conditions 2059:10.1176/ajp.135.9.1097 759: 668: 635: 411: 310:Differential diagnosis 89:Differential diagnosis 1732:Archives of Neurology 1471:"When the Bell Rings" 762: 757: 737:Mania appropriately. 666: 626: 546:dopamine transporters 466:Further information: 409: 401:dopamine transporters 2193:10.4088/jcp.v68n0102 1823:Molecular Psychiatry 1487:10.4088/PCC.19l02511 1368:Wetli, C.V. (2005), 304:Hidden figures tests 296:drawing a clock-face 289:Physical examination 1782:(9799): 1306–1315. 1608:10.1155/2012/720354 844:Stimulant Psychosis 564:People with severe 2874:10.1176/ajp.6.2.97 2641:10.1007/bf01813829 2134:The Neuroscientist 1892:10.1007/BF00427820 1880:Psychopharmacology 1835:10.1038/mp.2017.16 1539:Fink, Max (1999). 1370:"Excited Delirium" 985:"Excited Delirium" 760: 680:and Intramuscular 669: 636: 613:multiorgan failure 605:metabolic acidosis 544:and low levels of 482:drug sensitization 476:mechanism include 412: 223:Catatonic symptoms 215:emotional lability 142:emotional lability 2834:10.1520/JFS11020J 1665:978-0-203-44696-6 1545:Bipolar Disorders 1541:"Delirious mania" 1391:978-0-12-369399-0 1315:"Delirious Mania" 1107:10.1520/jfs14064j 1057:10.1520/jfs11020j 555:users and abusers 508:dopamine levels. 474:hyperdopaminergic 468:Reverse tolerance 440:nucleus accumbens 294:taken, including 185:Clinical features 115: 114: 16:Medical condition 2911: 2885: 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424:bipolar disorder 371:involved in the 369:neurotransmitter 328:bipolar disorder 263:hyperventilation 154:excited delirium 120:, also known as 39: 19: 2919: 2918: 2914: 2913: 2912: 2910: 2909: 2908: 2889: 2888: 2858: 2855: 2853:Further reading 2850: 2849: 2815: 2814: 2810: 2768: 2767: 2758: 2729:(10): 531–532. 2716: 2715: 2711: 2669: 2668: 2664: 2622: 2621: 2617: 2575: 2574: 2570: 2561: 2559: 2551: 2550: 2546: 2496: 2495: 2491: 2482: 2480: 2472: 2471: 2467: 2417: 2416: 2412: 2383:(9): 985–1028. 2370: 2369: 2365: 2323: 2322: 2318: 2276: 2275: 2271: 2221: 2220: 2216: 2174: 2173: 2169: 2127: 2126: 2122: 2087: 2086: 2082: 2040: 2039: 2035: 1985: 1984: 1980: 1928: 1927: 1923: 1873: 1872: 1868: 1816: 1815: 1811: 1772: 1771: 1767: 1725: 1724: 1717: 1683: 1682: 1678: 1670: 1668: 1666: 1642: 1641: 1634: 1588: 1587: 1580: 1538: 1537: 1510: 1468: 1467: 1456: 1414: 1413: 1404: 1396: 1394: 1392: 1367: 1366: 1362: 1312: 1311: 1302: 1248: 1247: 1240: 1186: 1185: 1130: 1088: 1087: 1080: 1038: 1037: 1026: 982: 981: 952: 925: 924: 920: 876: 875: 862: 857: 835: 797: 765: 752: 743: 695: 674: 654:Benzodiazepines 641: 628:Benzodiazepines 588: 580: 553:Psychostimulant 534: 498: 470: 464: 459: 417: 379:concerned with 373:pathophysiology 367:is the primary 362: 360:Pathophysiology 341: 318:and delusional 312: 291: 271: 191:psychostimulant 187: 170:Psychostimulant 122:delirious mania 30:Delirious mania 17: 12: 11: 5: 2917: 2915: 2907: 2906: 2901: 2891: 2890: 2887: 2886: 2854: 2851: 2848: 2847: 2828:(3): 873–880. 2808: 2756: 2709: 2682:(2): 101–104. 2662: 2635:(1): 614–634. 2615: 2588:(3): 187–191. 2568: 2544: 2509:(4): 385–386. 2489: 2465: 2430:(5): 265–268. 2410: 2363: 2336:(6): 688–697. 2316: 2289:(4): 335–340. 2269: 2214: 2167: 2140:(3): 181–198. 2120: 2101:(5): 897–905. 2080: 2033: 1998:(6): 616–617. 1978: 1941:(1): 266–275. 1921: 1866: 1829:(5): 666–679. 1809: 1765: 1738:(5): 547–551. 1715: 1696:(4): 554–556. 1676: 1664: 1632: 1578: 1508: 1454: 1427:(3): 312–316. 1402: 1390: 1360: 1300: 1255:BMC Psychiatry 1238: 1128: 1078: 1051:(3): 873–880. 1024: 950: 937:10.36740/emems 918: 889:(3): 285–288. 883:Psychosomatics 859: 858: 856: 853: 852: 851: 846: 841: 834: 831: 796: 793: 785:hallucinations 781:United Kingdom 764: 761: 751: 748: 742: 739: 718: 717: 714: 711: 705: 702: 694: 691: 673: 670: 640: 639:Rapid Sedation 637: 609:rhabdomyolysis 587: 584: 579: 576: 575: 574: 571: 568: 566:manic episodes 562: 559: 556: 533: 530: 497: 494: 463: 460: 458: 455: 416: 413: 403:dysfunction. 377:neural circuit 361: 358: 340: 337: 311: 308: 300:Face-Hand test 290: 287: 270: 267: 186: 183: 166:neural circuit 164:levels in the 136:, followed by 113: 112: 109: 103: 102: 99: 95: 94: 91: 85: 84: 80: 74: 73: 70: 66: 65: 62: 56: 55: 52: 46: 45: 41: 40: 32: 31: 28: 24: 23: 15: 13: 10: 9: 6: 4: 3: 2: 2916: 2905: 2902: 2900: 2897: 2896: 2894: 2883: 2879: 2875: 2871: 2868:(2): 97–127. 2867: 2863: 2857: 2856: 2852: 2843: 2839: 2835: 2831: 2827: 2823: 2819: 2812: 2809: 2804: 2800: 2796: 2792: 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723: 715: 712: 709: 706: 703: 700: 699: 698: 692: 690: 687: 683: 679: 671: 665: 661: 659: 655: 651: 650:catecholamine 647: 638: 633: 629: 625: 621: 619: 614: 610: 606: 602: 598: 594: 585: 583: 577: 572: 569: 567: 563: 560: 557: 554: 551: 550: 549: 547: 543: 542:sensitization 539: 531: 529: 527: 523: 519: 515: 509: 507: 506:extracellular 503: 495: 493: 491: 487: 483: 479: 475: 469: 461: 456: 454: 452: 448: 443: 441: 437: 433: 429: 425: 421: 414: 408: 404: 402: 398: 394: 393:sensitization 390: 389:extracellular 386: 382: 378: 374: 370: 366: 359: 357: 353: 351: 347: 336: 333: 329: 325: 324:schizophrenia 321: 317: 309: 307: 305: 301: 297: 288: 286: 284: 280: 276: 268: 266: 264: 260: 256: 252: 248: 244: 240: 236: 232: 228: 224: 220: 216: 212: 211:consciousness 208: 204: 200: 196: 192: 184: 182: 179: 175: 171: 167: 163: 159: 155: 151: 147: 146:consciousness 143: 139: 135: 131: 127: 123: 119: 110: 108: 104: 100: 96: 92: 90: 86: 81: 79: 75: 71: 67: 63: 61: 57: 53: 51: 47: 42: 38: 33: 29: 25: 20: 2899:Neuroscience 2865: 2861: 2825: 2821: 2811: 2778: 2774: 2726: 2722: 2712: 2679: 2675: 2665: 2632: 2628: 2618: 2585: 2581: 2571: 2560:. Retrieved 2556: 2547: 2506: 2502: 2492: 2481:. Retrieved 2477: 2468: 2427: 2423: 2413: 2380: 2376: 2366: 2333: 2329: 2319: 2286: 2282: 2272: 2234:(1): 57–62. 2231: 2227: 2217: 2187:(1): 11–21. 2184: 2180: 2170: 2137: 2133: 2123: 2098: 2094: 2083: 2050: 2046: 2036: 1995: 1991: 1981: 1938: 1934: 1924: 1883: 1879: 1869: 1826: 1822: 1812: 1779: 1775: 1768: 1735: 1731: 1693: 1689: 1679: 1669:, retrieved 1647: 1598: 1594: 1551:(1): 54–60. 1548: 1544: 1478: 1474: 1424: 1420: 1395:, retrieved 1373: 1363: 1325:(1): 15–28. 1322: 1318: 1258: 1254: 1196: 1192: 1101:(1): 25–31. 1098: 1094: 1048: 1044: 995:(1): 77–83. 992: 988: 927: 921: 886: 882: 814: 798: 766: 744: 741:Epidemiology 719: 696: 675: 658:Neuroleptics 642: 589: 581: 535: 532:Risk Factors 526:hypertension 514:hyperthermia 510: 499: 471: 444: 418: 363: 354: 342: 313: 292: 278: 274: 272: 259:hypertension 251:hyperthermia 188: 150:hyperthermia 121: 118:Bell's mania 117: 116: 78:Risk factors 22:Bell's mania 2503:Anaesthesia 773:Luther Bell 708:blood tests 586:Recognition 536:Given that 518:tachycardia 316:grandiosity 255:tachycardia 138:grandiosity 27:Other names 2893:Categories 2781:(1): 1–2. 2562:2021-05-24 2483:2021-04-10 1776:The Lancet 1671:2021-04-01 1601:: 720354. 1397:2021-04-01 855:References 806:depression 730:Dantrolene 486:mesolimbic 239:stereotypy 231:negativism 227:echopraxia 144:, altered 107:Medication 83:conditions 2904:Neurology 2882:0002-953X 2795:0195-7910 2743:0196-0644 2696:0379-0738 2649:0003-9373 2602:0735-6757 2523:0003-2409 2444:0969-9546 2397:0735-6757 2350:0196-0644 2303:0735-6757 2248:0277-0008 2201:0160-6689 2154:1073-8584 2067:0002-953X 2028:207428569 2012:0095-2990 1955:0270-6474 1900:0033-3158 1843:1476-5578 1752:0375-8540 1702:0702-8466 1565:1399-5618 1503:215758935 1441:0165-0327 1339:1538-1145 1277:1471-244X 1215:1664-042X 1115:0022-1198 1065:0022-1198 1001:1936-900X 931:. ALUNA. 905:1545-7206 818:psychosis 597:autonomic 428:PET scans 385:psychosis 332:catatonia 269:Diagnosis 235:echolalia 207:psychosis 158:catatonia 156:(EXD) or 134:psychosis 98:Treatment 50:Specialty 2704:12084484 2657:38213417 2610:11326341 2539:35080299 2531:11284850 2452:17823561 2405:19091264 2264:24505811 2209:17284125 2162:85237863 2115:21440403 2020:22783894 1916:22272809 1861:28289283 1804:25512763 1796:21851976 1760:14404003 1627:23198239 1573:11256658 1495:32286746 1449:18191210 1355:10286031 1347:23334676 1295:22716018 1233:27790150 1019:21691475 913:19567770 833:See also 789:delirium 777:delirium 769:etiology 734:acidosis 682:Ketamine 656:or  646:dopamine 601:dopamine 447:striatum 365:Dopamine 350:delirium 320:ideation 219:paranoid 199:delirium 178:ketamine 174:sedation 162:dopamine 126:delirium 60:Symptoms 2842:4031813 2803:3578198 2751:7283219 2460:1197543 2358:9624307 2311:9217519 2256:9469682 1973:8423473 1964:6576317 1908:6405435 1852:5401767 1710:2813636 1618:3502817 1286:3503657 1224:5061757 1199:: 435. 1123:8988571 1073:4031813 1010:3088378 945:7546377 750:History 593:autopsy 285:(WHO). 2880:  2840:  2801:  2793:  2749:  2741:  2702:  2694:  2655:  2647:  2608:  2600:  2537:  2529:  2521:  2458:  2450:  2442:  2403:  2395:  2356:  2348:  2309:  2301:  2262:  2254:  2246:  2207:  2199:  2160:  2152:  2113:  2073:  2065:  2026:  2018:  2010:  1971:  1961:  1953:  1914:  1906:  1898:  1859:  1849:  1841:  1802:  1794:  1758:  1750:  1708:  1700:  1662:  1625:  1615:  1571:  1563:  1501:  1493:  1447:  1439:  1388:  1353:  1345:  1337:  1293:  1283:  1275:  1261:: 65. 1231:  1221:  1213:  1121:  1113:  1071:  1063:  1017:  1007:  999:  943:  911:  903:  399:, and 298:, The 261:, and 247:mutism 69:Causes 2653:S2CID 2535:S2CID 2478:WebMD 2456:S2CID 2260:S2CID 2158:S2CID 2075:29501 2024:S2CID 1912:S2CID 1800:S2CID 1499:S2CID 1481:(2). 1351:S2CID 941:S2CID 802:panic 420:Mania 203:mania 130:mania 2878:ISSN 2838:PMID 2799:PMID 2791:ISSN 2747:PMID 2739:ISSN 2700:PMID 2692:ISSN 2645:ISSN 2606:PMID 2598:ISSN 2527:PMID 2519:ISSN 2448:PMID 2440:ISSN 2401:PMID 2393:ISSN 2354:PMID 2346:ISSN 2307:PMID 2299:ISSN 2252:PMID 2244:ISSN 2205:PMID 2197:ISSN 2150:ISSN 2111:PMID 2071:PMID 2063:ISSN 2016:PMID 2008:ISSN 1969:PMID 1951:ISSN 1904:PMID 1896:ISSN 1857:PMID 1839:ISSN 1792:PMID 1756:PMID 1748:ISSN 1706:PMID 1698:ISSN 1660:ISBN 1623:PMID 1599:2012 1569:PMID 1561:ISSN 1491:PMID 1445:PMID 1437:ISSN 1386:ISBN 1343:PMID 1335:ISSN 1291:PMID 1273:ISSN 1229:PMID 1211:ISSN 1119:PMID 1111:ISSN 1069:PMID 1061:ISSN 1015:PMID 997:ISSN 909:PMID 901:ISSN 787:and 724:and 632:GABA 330:and 302:and 237:and 213:and 176:and 2870:doi 2830:doi 2783:doi 2731:doi 2684:doi 2680:126 2637:doi 2633:102 2590:doi 2511:doi 2432:doi 2385:doi 2338:doi 2291:doi 2236:doi 2189:doi 2142:doi 2103:doi 2055:doi 2051:135 2000:doi 1959:PMC 1943:doi 1888:doi 1847:PMC 1831:doi 1784:doi 1780:378 1740:doi 1652:doi 1613:PMC 1603:doi 1553:doi 1483:doi 1429:doi 1425:109 1378:doi 1327:doi 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Index

A neurobehavioral syndromic disorder
Specialty
Symptoms
Risk factors
Differential diagnosis
Medication
delirium
mania
psychosis
grandiosity
emotional lability
consciousness
hyperthermia
excited delirium
catatonia
dopamine
neural circuit
Psychostimulant
sedation
ketamine
psychostimulant
neurological conditions
delirium
mania
psychosis
consciousness
emotional lability
paranoid
Catatonic symptoms
echopraxia

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