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Benzene in soft drinks

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145: 2205: 2216: 416:, the federal drinking water limit) while four drinks contained amounts above the standard. Two of these drinks contained amounts 15-18 times above the drinking water standard. Many of the products showed large variations in the amount of benzene they contained. The FDA stated that it is working with manufacturers to reformulate products that contain benzene above the federal drinking water standard. 2236: 2246: 2195: 2226: 259:
Air: A European study found that people breathe in 220 μg of benzene every day due to general atmospheric pollution. A motorist refilling a fuel tank for three minutes would inhale a further 32 μg. The estimated daily exposure from "automobile-related activities" is 49 μg and for driving for one hour
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Benzene in soft drinks has to be seen in the context of other environmental exposure. Taking the worst example found to date of a soft drink containing 87.9 ppb benzene, someone drinking a 350 ml (12 oz) can would ingest 31 μg (micrograms) of benzene, almost equivalent to the benzene inhaled by
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The UK Food Standards Agency has stated that people would need to drink at least 20 litres (5.5 gal) per day of a drink containing benzene at 10 μg to equal the amount of benzene they would breathe from city air every day. Daily personal exposure to benzene is determined by adding exposure from all
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released its study results of benzene levels in beverages. Four products out of 118 had levels above the Canadian guideline of five micrograms per liter for benzene in drinking water (average range 6.0 to 23.0 μg/L). The follow-up study the next year found only three samples with marginally
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a motorist refilling a fuel tank for three minutes. While there are alternatives to using sodium benzoate as a preservative, the casual consumption of such a drink is unlikely to pose a significant health hazard to a particular individual (see, for example, the EPA IRIS document on benzene).
1825: 1040: 405:. It said the detected amount of benzene – ranging from 5.7 to 87.8 ppb – was not harmful to humans but advised manufacturers of beverages containing more than 10 ppb of benzene to voluntarily recall their products. 57:, especially under heat and light. Hot peppers naturally contain vitamin C ("nearly as much as in one orange") so the observation about soft drinks applies to pepper sauces containing sodium benzoate, like 315:
In the summer of 1998, a number of well known soft drinks manufacturers had to withdraw large quantities of their products from sale after benzene contamination in some production plants was discovered.
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These test results are both lower and more accurate than a previous long-term study by the FDA. In the Total Diet Study that FDA conducted from 1996 - 2001 to determine the amounts of
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Smoking: For smokers, cigarette smoking is the main source of exposure to benzene. Estimates are 7900 μg per day (smoking 20 cigarettes per day), 1820 μg/day, and 1800 μg/day.
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concern and has caused significant outcry among environmental and health advocates. Benzene levels are regulated in drinking water nationally and internationally, and in
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Gardner, L.K.; Lawrence, G.D. (May 1993). "Benzene Production from Decarboxylation of Benzoic Acid in the Presence of Ascorbic Acid and a Transition-Metal Catalyst".
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formation in soft drinks. Following testing, FDA asked manufacturers to voluntarily reformulate. By 1993, FDA determined that most drinks had little
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Monitoring the Benzene Contents in Soft Drinks Using Headspace Gas Chromatography−Mass Spectrometry: A Survey of the Situation on the Belgian Market
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released results on March 31, 2006 for 150 beverages. Its results showed 43 beverages contained benzene, four of which contained levels above the
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Other factors that affect the formation of benzene are heat and light. Storing soft drinks in warm conditions speeds up the formation of benzene.
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is not thought to induce significant benzene production in combination with benzoic acid, but some evidence suggests that in the presence of
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released preliminary results in May 2006 for 100 beverages showing that many soft drinks contained low levels of benzene (less than 5
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United States Food and Drug Administration: Questions and Answers on the Occurrence of Benzene in Soft Drinks and Other Beverages
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to reveal exactly which amounts of benzene, if any, were present, with several other organizations awaiting their findings.
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received test results conducted by private citizens that benzene was forming at low levels in several types of beverages.
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The International Council of Beverages Associations (ICBA) has produced advice to prevent or minimize benzene formation.
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Hildeman, Bette. "Dispute Over Benzene In Drinks", Chemical and Engineering News, April 24, , Vol. 84, pg 10.
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Various authorities have set limits on benzene content in drinking water. The following limits are given in
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and pose no risk to consumers. Furthermore, there are no standards for beverages beyond drinking and
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Council Directive 98/83/EC of 3 November 1998 on the quality of water intended for human consumption
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Food and Drug Administration, U.S. Public Health Service, Department of Health and Human Services
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HEXPOC Human Exposure Characterization of chemical substances; quantification of exposure routes
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In 1993, research showed how benzene can form from benzoic acid in the presence of vitamin C.
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root beer still contained benzoate (added as potassium salt and sodium salt respectively).
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announced that it would be phasing out sodium benzoate from many of its drinks, but not
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ICBA Guidance Document to Mitigate the Potential for Benzene Formation in Beverages
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in the United States, but only informally in soft drinks. The benzene forms from
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Coca-Cola to phase out use of controversial additive after DNA damage claim
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Indications of the possible formation of benzene from benzoic acid in foods
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procedure that caused more benzene to form in the drinks during the test.
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and sugars have been shown to inhibit benzene production in soft drinks.
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for sale in the United States, resulting in a voluntary product recall.
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and benzoic acid, citric acid may accelerate the production of benzene.
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may play an important role in the formation of benzene in soft drinks.
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Perrier Recalls Its Water in U.S. After Benzene Is Found in Bottles
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On 24 August 2006, two soft drink manufacturers agreed to settle a
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may be created as part of a chemical reaction during production of
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New Zealand Food Safety Authority / Te Pou Oranga kai O Aotearoa
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In the early 1990s, the soft drink industry initially approached
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have set public health goals for benzene of 0 ppb and 0.15 ppb.
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A Follow-up survey of benzene in soft drinks and other products
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higher levels and concluded the average levels were quite low.
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flavor. Full-scale investigations immediately started at the
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Coca-Cola agrees to take carcinogenic benzene out of soda
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lawsuit that had been filed by a group of parents in the
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emphasized that most beverages contain levels below 5
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2024 United Kingdom Shigatoxigenic E. coli outbreak
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This contamination is a 272:Diet and drinking water: 0.2 to 3.1 μg per day. 887:"UK, Germany checking soft drinks for benzene" 779:Letter Regarding Benzene Levels in Soft Drinks 1114: 8: 2129:Spanish Agency for Food Safety and Nutrition 1944:2017–2018 South African listeriosis outbreak 1843:1985 Austrian diethylene glycol wine scandal 692: 690: 688: 2067:United Kingdom food information regulations 721:European Commission Joint Research Centre, 645:Integrated Risk Information System: Benzene 1121: 1107: 1099: 824: 822: 459:Superior Court of the District of Columbia 335:'s Federal Institute for Risk Assessment ( 1905:2008 United States salmonellosis outbreak 905:"Survey of benzene levels in soft drinks" 1949:2018 Australian strawberry contamination 1811:Morinaga Milk arsenic poisoning incident 1018:Soft Drink Companies Settle Benzene Case 589: 587: 585: 552: 550: 480:. As of August 2012, Coca-Cola Zero and 394:). These four were withdrawn from sale. 202:: federal limit: 5 ppb; state limits in 1919:2011 United States listeriosis outbreak 967:"FDA Statement: Benzene in Soft Drinks" 499: 286:In 1990, a study reported having found 1934:2015 Mozambique funeral beer poisoning 1511:Ethylenediaminetetraacetic acid (EDTA) 668: 666: 664: 662: 660: 16:Concern due to possible contamination 7: 2225: 2113:Institute for Food Safety and Health 1853:Australian meat substitution scandal 1821:Moroccan oil poisoning disaster 1959 1597:Arsenic contamination of groundwater 508:"Is hot sauce good for your health?" 399:Korea Food & Drug Administration 347:In February 2006, an unnamed former 2245: 2101:Food Information and Control Agency 124:The proposed mechanism begins with 26:is of potential concern due to the 351:at the FDA publicly revealed that 337:Bundesinstitut für Risikobewertung 246:Benzene § Exposure to benzene 132:, which itself is produced by the 14: 2118:International Food Safety Network 2042:International Food Safety Network 1763:Variant Creutzfeldt–Jakob disease 1713:Acid-hydrolyzed vegetable protein 1440:Shigatoxigenic and verotoxigenic 1094:Soft Drinks and Benzene: A Primer 791:"Cancer chemical found in drinks" 702:"Survey of Benzene in Soft Drinks 643:Environmental Protection Agency. 240:Environmental exposure to benzene 164:Limit standards in drinking water 2244: 2234: 2224: 2215: 2214: 2203: 2193: 2123:Ministry of Food and Drug Safety 1959:Kobayashi red yeast rice scandal 1890:2008 Canada listeriosis outbreak 1885:ICA meat repackaging controversy 143: 2062:Quality Assurance International 1969:Food safety incidents in Taiwan 1939:2017 Brazil Operation Weak Meat 1833:1971 Iraq poison grain disaster 1748:Polycyclic aromatic hydrocarbon 359:, particularly those having an 2091:European Food Safety Authority 1964:Food safety incidents in China 1801:1858 Bradford sweets poisoning 1768:Water fluoridation controversy 423:in various foods, FDA used an 93:is often added to drinks as a 1: 654:Accessed on November 27, 2006 626:Consumer Factsheet on Benzene 390:drinking water standards (10 2096:Food and Drug Administration 1778:Food contamination incidents 963:Food and Drug Administration 948:Food and Drug Administration 733:, pp36–59, 2005, EU 21501 EN 2150:Food and drink prohibitions 1924:Bihar school meal poisoning 1848:United Kingdom BSE outbreak 1806:1900 English beer poisoning 1160:Antibiotic use in livestock 1077:Christof van Poucke et al. 892:September 27, 2007, at the 869:September 27, 2007, at the 674:Benzene in flavoured drinks 650:September 14, 2015, at the 487:A Belgian study found that 2302: 2145:Curing (food preservation) 1218:Monosodium glutamate (MSG) 965:(US FDA). April 13, 2006, 935:September 7, 2008, at the 421:volatile organic compounds 243: 2188: 2175:Genetically modified food 2027:Food labeling regulations 1895:2008 Chinese milk scandal 1023:January 14, 2009, at the 1004:December 2, 2016, at the 910:February 4, 2012, at the 388:World Health Organization 181:World Health Organization 97:in the form of its salts 89:of ascorbic acid, E315). 2037:Food safety in Australia 1233:High-fructose corn syrup 707:October 9, 2014, at the 136:-catalysed reduction of 65:Formation in soft drinks 2017:Acceptable daily intake 1929:2013 horse meat scandal 1370:Clostridium perfringens 1043:April 23, 2010, at the 749:April 18, 2008, at the 679:April 23, 2007, at the 631:April 13, 2006, at the 599:April 11, 2008, at the 576:April 17, 2016, at the 2085:Centre for Food Safety 1900:2008 Irish pork crisis 1602:Benzene in soft drinks 846:July 19, 2011, at the 813:July 23, 2008, at the 767:FDA Enforcement Report 324:In November 2005, the 2276:Medical controversies 2107:Food Standards Agency 2057:Organic certification 2052:Nutrition facts label 1796:Esing Bakery incident 1584:environment pollution 1065:May 19, 2016, at the 885:, February 20, 2006, 883:Food Production Daily 862:, February 15, 2006, 860:Food Production Daily 697:Food Standards Agency 384:Food Standards Agency 365:Food Standards Agency 81:(vitamin C, E300) or 1876:2006 North American 1534:Acesulfame potassium 1363:Campylobacter jejuni 1257:Intestinal parasites 1130:Consumer food safety 1060:Retrieved 2014-10-12 529:J. Agric. Food Chem. 301:with concerns about 126:hydrogen abstraction 2180:Conspiracy theories 1733:Heterocyclic amines 1637:Shellfish poisoning 828:FDA. May 19, 2006, 541:10.1021/jf00029a001 397:In April 2006, the 186:Republic of Korea ( 77:in the presence of 49:in the presence of 1838:Toxic oil syndrome 1791:Swill milk scandal 1617:Diethylstilbestrol 1289:Diphyllobothriasis 952:"Total Diet Study" 922:Elliott, Valerie, 754:The New York Times 510:. 4 November 2016. 331:In December 2005, 140:by ascorbic acid: 103:potassium benzoate 2258: 2257: 2165:Food preservation 1974:Foodborne illness 1526:Sugar substitutes 1279:Cryptosporidiosis 1261:parasitic disease 1175:HGH controversies 1142:food contaminants 1027:, August 24, 2006 928:, April 1, 2006, 769:February 28, 1990 756:February 10, 1990 489:plastic packaging 170:parts per billion 153:Calcium disodium 2293: 2248: 2247: 2238: 2228: 2227: 2218: 2217: 2210:Drink portal 2208: 2207: 2206: 2198: 2197: 2109:(United Kingdom) 1858:Jack in the Box 1829: 1816:Minamata disease 1728:Food irradiation 1708:4-Hydroxynonenal 1556:Sodium cyclamate 1399:Escherichia coli 1391:Escherichia coli 1123: 1116: 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1407: 1404: 1402: 1400: 1396: 1394: 1392: 1388: 1386: 1385: 1381: 1379: 1378: 1374: 1372: 1371: 1367: 1365: 1364: 1360: 1358: 1355: 1354: 1352: 1350: 1346: 1340: 1337: 1335: 1332: 1330: 1329:Toxoplasmosis 1327: 1325: 1322: 1320: 1317: 1315: 1312: 1310: 1307: 1305: 1302: 1300: 1297: 1295: 1292: 1290: 1287: 1285: 1282: 1280: 1277: 1275: 1272: 1270: 1267: 1266: 1264: 1262: 1258: 1254: 1246: 1243: 1242: 1241: 1240:Vegetable oil 1238: 1234: 1231: 1230: 1229: 1226: 1224: 1221: 1219: 1216: 1214: 1211: 1210: 1208: 1206: 1202: 1196: 1193: 1191: 1188: 1186: 1183: 1181: 1178: 1176: 1173: 1171: 1168: 1166: 1163: 1161: 1158: 1156: 1153: 1151: 1148: 1147: 1145: 1143: 1139: 1135: 1131: 1124: 1119: 1117: 1112: 1110: 1105: 1104: 1101: 1095: 1092: 1091: 1087: 1080: 1074: 1071: 1068: 1064: 1061: 1056: 1053: 1049: 1046: 1042: 1039: 1033: 1030: 1026: 1022: 1019: 1013: 1010: 1007: 1003: 1000: 995: 992: 988: 983: 980: 974: 971: 968: 964: 959: 956: 953: 949: 944: 941: 938: 934: 931: 927: 926: 919: 916: 913: 909: 906: 901: 898: 895: 891: 888: 884: 878: 875: 872: 868: 865: 861: 855: 852: 849: 845: 842: 837: 834: 831: 825: 823: 819: 816: 812: 809: 804: 801: 796: 792: 786: 783: 780: 775: 772: 768: 762: 759: 755: 752: 748: 745: 742:George James 739: 736: 732: 730: 729: 725: 724: 718: 715: 711: 710: 706: 703: 698: 693: 691: 689: 685: 682: 678: 675: 669: 667: 665: 663: 661: 657: 653: 649: 646: 640: 637: 634: 630: 627: 622: 619: 615: 614: 608: 605: 602: 598: 595: 590: 588: 586: 582: 579: 575: 572: 571: 564: 561: 558: 553: 551: 547: 542: 538: 534: 531: 530: 522: 520: 518: 514: 509: 503: 500: 494: 492: 490: 485: 483: 479: 475: 471: 464: 462: 460: 456: 451: 448: 447:Health Canada 443: 441: 440:bottled water 437: 433: 428: 426: 422: 417: 415: 411: 406: 404: 400: 395: 393: 389: 385: 381: 376: 374: 370: 366: 362: 358: 354: 350: 342: 340: 338: 334: 329: 327: 319: 317: 313: 310: 308: 304: 300: 295: 293: 289: 281: 276: 271: 268: 265: 262: 258: 257: 256: 252: 247: 239: 237: 235: 231: 223: 220: 217: 213: 209: 205: 201: 200:United States 198: 195: 192: 189: 185: 182: 179: 178: 177: 175: 171: 163: 161: 158: 156: 151: 148: 146: 141: 139: 135: 131: 127: 122: 120: 116: 112: 108: 104: 100: 96: 92: 88: 84: 80: 79:ascorbic acid 76: 72: 64: 62: 60: 56: 52: 51:ascorbic acid 48: 45: 41: 37: 36:bottled water 33: 32:public health 29: 25: 21: 2170:Food quality 2077:Institutions 1911: 1877: 1868: 1859: 1743:Nitrosamines 1601: 1506:Benzoic acid 1468:Chlorpyrifos 1447: 1441: 1432: 1415: 1398: 1390: 1382: 1375: 1368: 1361: 1339:Trichuriasis 1324:Toxocariasis 1294:Enterobiasis 1170:Formaldehyde 1073: 1055: 1047: 1032: 1016:LIBBY QUAID 1012: 994: 982: 973: 958: 943: 923: 918: 900: 882: 877: 859: 854: 836: 803: 794: 785: 774: 761: 753: 738: 731: 728: 722: 717: 700: 639: 621: 611: 607: 569: 563: 532: 527: 502: 486: 468: 455:class-action 452: 444: 429: 418: 407: 396: 377: 346: 336: 330: 323: 314: 311: 296: 285: 253: 249: 227: 167: 159: 152: 149: 142: 123: 105:(E 212), or 95:preservative 91:Benzoic acid 87:diastereomer 75:benzoic acid 68: 47:benzoic acid 44:preservative 28:carcinogenic 18: 2281:Food safety 2271:Soft drinks 2250:WikiProject 2087:(Hong Kong) 1824: [ 1786:Devon colic 1660:Breast milk 1632:Nonylphenol 1607:Bisphenol A 1544:controversy 1411:Hepatitis E 1406:Hepatitis A 1384:Enterovirus 1377:Cronobacter 1334:Trichinosis 1304:Fasciolosis 1274:Anisakiasis 1245:controversy 1138:Adulterants 1050:25 May 2008 403:South Korea 357:soft drinks 208:Connecticut 188:South Korea 111:Citric acid 24:soft drinks 2265:Categories 2001:Regulation 1984:death toll 1753:Shortening 1718:Acrylamide 1647:Food fraud 1627:Mycotoxins 1460:Pesticides 1434:Salmonella 1309:Giardiasis 1269:Amoebiasis 1213:Flavorings 495:References 425:analytical 244:See also: 234:California 212:New Jersey 204:California 59:Texas Pete 2047:ISO 22000 2009:watchdogs 2005:standards 1979:outbreaks 1880:outbreaks 1758:Trans fat 1670:Olive oil 1592:Aflatoxin 1566:Sucralose 1551:Saccharin 1539:Aspartame 1483:Malathion 1428:Rotavirus 1423:Norovirus 950:(US FDA) 925:The Times 470:Coca-Cola 371:) and in 260:is 40 μg. 255:sources. 190:): 10 ppb 109:(E 213). 55:catalysts 2240:Cookbook 2220:Category 2022:E number 1914:outbreak 1871:outbreak 1862:outbreak 1612:Dieldrin 1561:Sorbitol 1417:Listeria 1357:Botulism 1185:Melamine 1155:Aldicarb 1063:Archived 1041:Archived 1021:Archived 1002:Archived 933:Archived 908:Archived 890:Archived 867:Archived 844:Archived 811:Archived 795:BBC News 747:Archived 705:Archived 677:Archived 648:Archived 629:Archived 597:Archived 574:Archived 138:dioxygen 115:ascorbic 101:(E211), 2286:Benzene 2230:Commons 2103:(Spain) 1912:E. coli 1878:E. coli 1869:E. coli 1860:E. coli 1680:Seafood 1580:poisons 1478:Lindane 1442:E. coli 1401:O157:H7 1393:O104:H4 1195:Sudan I 1165:Cyanide 373:Germany 353:benzene 349:chemist 333:Germany 307:benzene 303:benzene 292:Perrier 288:benzene 277:History 224:: 1 ppb 218:: 1 ppb 216:Florida 196:: 5 ppb 128:by the 42:of the 20:Benzene 1685:Shrimp 1622:Dioxin 1576:Toxins 1150:3-MCPD 989:, 2007 482:Barq's 478:Sprite 361:orange 214:, and 194:Canada 176:/kg). 172:(ppb; 1828:] 1675:Prawn 1655:Bread 1228:Sugar 712:(PDF) 616:(PDF) 474:Fanta 282:1990s 1223:Salt 476:and 465:2008 430:The 408:The 378:The 343:2006 320:2005 232:and 228:The 155:EDTA 1690:Tea 1665:Egg 1473:DDT 537:doi 436:ppb 432:FDA 414:ppb 410:FDA 392:ppb 382:'s 326:FDA 299:FDA 230:EPA 117:or 85:(a 73:of 22:in 2267:: 2007:, 2003:, 1826:ar 1582:, 1578:, 1259:, 1140:, 821:^ 793:. 687:^ 659:^ 584:^ 549:^ 533:41 516:^ 442:. 369:UK 210:, 206:, 174:μg 134:Cu 61:. 1122:e 1115:t 1108:v 543:. 539:: 367:(

Index

Benzene
soft drinks
carcinogenic
public health
bottled water
decarboxylation
preservative
benzoic acid
ascorbic acid
catalysts
Texas Pete
decarboxylation
benzoic acid
ascorbic acid
erythorbic acid
diastereomer
Benzoic acid
preservative
sodium benzoate
potassium benzoate
calcium benzoate
Citric acid
ascorbic
erythorbic acid
hydrogen abstraction
hydroxyl radical
Cu
dioxygen

EDTA

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