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basophil activation test, which gave indications of the clinical relevance and served for the risk assessment of alpha-gal-containing drugs including vaccines. In her paper published in 2022, she provided a detailed analysis of the performance of cellular tests (basophil activation or basophil histamine release test) with different vaccines, PEGs of different molecular weights, as well as other PEGylated drugs, and highlighted the results in the context of COVID-19 vaccination of various working groups worldwide.
246:
While exploring the role of ultraviolet A1 phototherapy in the treatment of localized scleroderma, she conducted a retrospective and prospective study and proved the efficacy of UVA1 phototherapy in these patients. In addition, the efficacy of UVA1 phototherapy in more than 200 patients with various
233:
She demonstrated in a review the application of BAT as a complementary to skin tests and sIgE and has regarded basophil activation test (BAT) as a powerful tool and sensitive marker that can be used to detect clinically relevant allergies, provide information on the severity of an allergic reaction,
229:
Eberlein focused in her studies on the use of basophil activation tests for questions on insect venom allergy, in particular to identify the clinically relevant insect in unclear cases. In addition, food allergy and in particular the alpha-gal syndrome was the subject of her investigations with the
1171:
Papo, David; Eberlein-König, Bernadette; Berresheim, Hans-Walter; Huss-Marp, Johannes; Grimm, Volker; Ring, Johannes; Behrendt, Heidrun; Winneke, Gerhard (February 2006). "Chemosensory function and psychological profile in patients with multiple chemical sensitivity: Comparison with odor-sensitive
197:
substances" at the
Department of Dermatology and Allergy Biederstein in 2000. She held appointment as a Senior Physician in the photodermatological unit, the unit for soft X-ray therapy as well as in the outpatient and inpatient area in 2004, and as a professor at the Department of Dermatology and
1055:
Eberlein, B.; Gulyas, A.; Schultz, K.; Lecheler, J.; Flögel, S.; Wolfmeyer, C.; Thiessen, K.; Gass, S.; Kroiss, M.; Huss-Marp, J.; Darsow, U.; Hollweck, R.; Schuster, T.; Behrendt, H.; Ring, J. (2009). "Benefits of alpine mountain climate of
Bavaria in patients with allergic diseases and chronic
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Huss-Marp, J.; Eberlein-König, B.; Breuer, K.; Mair, S.; Ansel, A.; Darsow, U.; Krämer, U.; Mayer, E.; Ring, J.; Behrendt, H. (March 2006). "Influence of short-term exposure to airborne Der p 1 and volatile organic compounds on skin barrier function and dermal blood flow in patients with atopic
255:
Eberlein carried out experiments in environmental exposure chambers to investigate the influence of air humidity, pollutants and allergens on the physiology of human skin. Furthermore, she investigated effects of alpine mountain climate of
Bavaria on atopic diseases with Heidrun Behrendt's and
242:
In her research regarding photosensitivity, Eberlein focused on the influence of photosensitizing substances and photoprotective substances such as antioxidants (vitamins C and E). Photosensitising properties of antimicrobials, food additives, fragrances, hypolipidemics, neuroleptic drugs,
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Eberlein-König, Bernadette; Przybilla, Bernhard; Kühnl, Patricia; Golling, Gabriele; Gebefügi, Istvan; Ring, Johannes (2002). "Multiple chemical sensitivity (MCS) and others: Allergological, environmental and psychological investigations in individuals with indoor air related complaints".
458:
Eberlein, Bernadette; Krischan, Lilian; Darsow, Ulf; Ollert, Markus; Ring, Johannes (July 2012). "Double positivity to bee and wasp venom: Improved diagnostic procedure by recombinant allergen–based IgE testing and basophil activation test including data about cross-reactive carbohydrate
243:
non-steroidal anti-inflammatory drugs, proton pump inhibitors, statins etc. were characterised in more detail together with
Bernhard Przybilla's working group. In a recent review she highlightened the vemurafenib-induced photosensitivity exclusively caused by UVA irradiation.
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2013 – Almirall
Dermatology Promotional Prize for the work "Double positivity to bee and wasp venom: improved diagnostic procedure by recombinant-allergen based IgE testing and basophil activation test including data about cross- reactive carbohydrate
543:
Schmidle, Paul; Mehlich, Jana; Brockow, Knut; Darsow, Ulf; Biedermann, Tilo; Eberlein, Bernadette (2021). "Gelatin-Containing
Vaccines for Varicella, Zoster, Measles, Mumps, and Rubella Induce Basophil Activation in Patients with Alpha-Gal Syndrome".
1083:
Eberlein, B.; Huss-Marp, J.; Pfab, F.; Fischer, R.; Franz, R.; Schlich, M.; Leibl, M.; Allertseder, V.; Liptak, J.; Kriegisch, M.; Hennico, R.; Latotski, J.; Ebner von
Eschenbach, C.; Darsow, U.; Buters, J.; Behrendt, H.; Huber, R.; Ring, J. (2014).
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Andres, C.; Kollmar, A.; Mempel, M.; Hein, R.; Ring, J.; Eberlein, B. (February 2010). "Successful ultraviolet A1 phototherapy in the treatment of localized scleroderma: a retrospective and prospective study: UVA1 therapy in localized scleroderma".
381:
687:
Eberlein-König, Bernadette; Placzek, Marianne; Przybilla, Bernhard (January 1998). "Protective effect against sunburn of combined systemic ascorbic acid (vitamin C) and d-α-tocopherol (vitamin E)".
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431:
Eberlein-König, B.; Rakoski, J.; Behrendt, H.; Ring, J. (2004). "Use of CD63 expression as marker of in vitro basophil activation in identifying the culprit in insect venom allergy".
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1086:"Influence of alpine mountain climate of Bavaria on patients with atopic diseases: studies at the Environmental Research Station Schneefernerhaus (UFS - Zugspitze) – a pilot study"
202:
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Rombold, S.; Lobisch, K.; Katzer, K.; Grazziotin, T. C.; Ring, J.; Eberlein, B. (February 2008). "Efficacy of UVA1 phototherapy in 230 patients with various skin diseases".
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Mehlich, J.; Fischer, J.; Hilger, C.; Swiontek, K.; Morisset, M.; Codreanu-Morel, F.; Schiener, M.; Blank, S.; Ollert, M.; Darsow, U.; Biedermann, T.; Eberlein, B. (2019).
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2018 – DGAKI Young Talent Award for the work "The basophil activation test differentiates between patients with alpha-gal syndrome and asymptomatic alpha-gal sensitization"
279:
sponsorship award "Skin and
Environment" for the work "Ultraviolet-A radiation induces adhesion molecule expression on human dermal microvascular endothelial cells."
972:"Influence of airborne nitrogen dioxide or formaldehyde on parameters of skin function and cellular activation in patients with atopic eczema and control subjects"
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Eberlein was chair (2019-2021), secretary (2017-2019) and board member (2015-2017) of the
Interest Group of Allergy Diagnosis & Systems Medicine (IGAD) at
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Parameter der UVB-Strahlungsempfindlichkeit des
Menschen: In-vitro- und In-vivo-Modelle zur PrĂĽfung photosensibilisierender und photoprotektiver Substanzen
272:
1991 – Grünenthal sponsorship award "Skin and Environment" for the work "Evidence of increased UV sensitivity in patients with malignant melanoma"
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1996 – Heinz Maurer Prize for Dermatological Research for the work "Change of skin roughness due to lowering air humidity in a climate chamber"
176:
146:
77:
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with a study scholarship of the Bavarian scholarship programme for gifted students, and completed her Study of medicine in 1989, and her
382:"eberlein b (munich or münchen or erlangen-nürnberg) or eberlein-koenig or eberlein-konig or eberlein-könig - Search Results - PubMed"
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496:"The basophil activation test differentiates between patients with alpha-gal syndrome and asymptomatic alpha-gal sensitization"
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125:
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332:"Bernadette Eberlein - Head of Dermatology, Pediatrics Allergy and Immunology in Munich, Bavaria, Germany | eMedEvents"
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Eberlein, Bernadette; Mathes, Sonja; Fischer, Jörg; Darsow, Ulf; Biedermann, Tilo; Brockow, Knut (October 2022).
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diagnostics, photodermatology, earlier in skin-physiological investigations, and environmental health disorders.
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in 1990, and then worked as a Doctor in Internship and Assistant Doctor in the Department of Dermatology of the
256:
Johannes Ring's working group. Patients with environmental health disorders were characterized in more detail.
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from 1992 to 1996. Later she was an assistant doctor at the Department of Dermatology and Allergy Biederstein,
413:
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diagnostics, photodermatology, skin-physiological investigations, and several environmental health disorders.
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970:
Eberlein-König, B.; Przybilla, B.; Kühnl, P.; Pechak, J.; Gebefügi, I.; Kleinschmidt, J.; Ring, J. (1998).
1241:
589:"Do basophil activation tests help elucidate allergic reactions to the ingredients in COVID-19 vaccines?"
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from 1996 to 2003 and completed her habilitation on "Parameters of UVB radiation sensitivity in humans:
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at the Department of Dermatology of the university in 1990. Her dissertation was titled "Influence of
1246:
171:
Eberlein started her post-doctoral training in the Institute for Clinical and Molecular Virology at
131:
Eberlein has authored over 100 publications in medical journals. She led research aimed at cellular
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1990 – Clemens von Pirquet grant for the dissertation: "Influence of ultraviolet radiation on the
205:. She was lead organizer of the EUROBAT meetings in the years 2010, 2014, 2016, 2018, 2020, 2022.
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1208:"ALMIRALL FÖRDERPREIS DERMATOLOLOGIE 2013 – NEUE KONZEPTE IN DIAGNOSTIK UND THERAPIE"
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638:"Basophil Activation as Marker of Clinically Relevant Allergy and Therapy Outcome"
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Eberlein, Bernadette; Biedermann, Tilo; Hein, RĂĽdiger; Posch, Christian (2020).
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746:"Association between Actinic Keratoses and Potentially Photosensitizing Drugs"
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Placzek, Marianne; Eberlein-König, Bernadette; Przybilla, Bernhard (1999).
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923:"Change of skin roughness due to lowering air humidity in climate chamber"
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361:"Dermatologie am Biederstein - Prof. Dr. med. Bernadette Eberlein"
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Journal of Investigational Allergology & Clinical Immunology
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Journal of Investigational Allergology & Clinical Immunology
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obstructive pulmonary disease: results from the AURA* study".
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International Journal of Hygiene and Environmental Health
791:
JDDG: Journal der Deutschen Dermatologischen Gesellschaft
414:"FAAM-EUROBAT Digital 2020 - Committees | EAACI.org"
269:
histamine release of peripheral mononuclear leukocytes"
921:
Eberlein-König, B.; Spiegl, A.; Przybilla, B. (1996).
880:
Photodermatology, Photoimmunology & Photomedicine
213:
Eberlein's research is primarily focused on cellular
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Academic staff of the Technical University of Munich
203:
European Academy of Allergy and Clinical Immunology
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83:
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39:
25:
18:
546:International Archives of Allergy and Immunology
247:skin diseases was retrospectively investigated.
173:Friedrich-Alexander-University Erlangen-NĂĽrnberg
976:The Journal of Allergy and Clinical Immunology
689:Journal of the American Academy of Dermatology
500:The Journal of Allergy and Clinical Immunology
116:, academic, and researcher. She is the Senior
1272:Ludwig Maximilian University of Munich alumni
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400:"Bernadette Eberlein - ResearchGate Profile"
461:Journal of Allergy and Clinical Immunology
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124:unit, the unit for Soft X-Ray Therapy at
193:models for testing photosensitizing and
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147:Ludwig-Maximilians-University in Munich
787:"Vemurafenib-related photosensitivity"
120:of the private outpatient clinic, the
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1222:"Wissenschaftspreise und Stipendien"
177:Ludwig-Maximilians-University Munich
78:Ludwig-Maximilians-University Munich
1014:Clinical & Experimental Allergy
1090:Clinical and Translational Allergy
164:release of peripheral mononuclear
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1174:Journal of Psychosomatic Research
1012:eczema and healthy individuals".
1186:10.1016/j.jpsychores.2005.06.075
1026:10.1111/j.1365-2222.2006.02448.x
892:10.1111/j.1600-0781.2008.00328.x
849:10.1111/j.1365-2133.2009.09438.x
198:Allergy in Biederstein in 2007.
750:New England Journal of Medicine
837:British Journal of Dermatology
126:Technical University of Munich
93:Technical University of Munich
1:
989:10.1016/S0091-6749(98)70212-X
701:10.1016/s0190-9622(98)70537-7
365:www.derma-allergie.med.tum.de
1172:and asymptomatic controls".
763:10.1056/NEJM199911043411915
181:Technical University Munich
1288:
927:Acta Dermato-Venereologica
513:10.1016/j.jaci.2018.06.049
473:10.1016/j.jaci.2012.02.008
58:, academic, and researcher
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940:10.2340/0001555576447449
655:10.3389/fimmu.2020.01815
1262:Physicians from Bavaria
1150:10.1078/1438-4639-00150
642:Frontiers in Immunology
234:and monitor therapies.
1103:10.1186/2045-7022-4-17
1252:German dermatologists
636:Eberlein, B. (2020).
251:Environmental health
145:Eberlein studied at
141:Education and career
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106:Bernadette Eberlein
67:Academic background
20:Bernadette Eberlein
1210:. 12 August 2013.
804:10.1111/ddg.14140
797:(10): 1079–1083.
756:(19): 1474–1475.
605:10.1111/all.15278
599:(10): 2924–2936.
558:10.1159/000514263
260:Awards and honors
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89:Institutions
1247:1964 births
225:diagnostics
155:ultraviolet
40:Nationality
1236:Categories
731:383221173X
341:2022-10-11
317:2022-10-11
294:References
277:GrĂĽnenthal
166:leukocytes
73:Alma mater
821:219901899
574:232304021
312:orcid.org
221:Cellular
162:histamine
151:Doctorate
118:Physician
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1158:12046597
1122:26085923
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1042:23522130
1034:16499645
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648:: 1815.
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566:33735861
530:52052530
522:30125663
481:22421265
445:15160437
267:in vitro
223:in vitro
215:in vitro
209:Research
185:in vitro
159:in vitro
134:in vitro
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998:9449520
949:8982408
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