Knowledge (XXG)

Berylliosis

Source πŸ“

248: 37: 422:
criteria for chronic beryllium disease. In one study of nuclear workers, among those who were sensitized to beryllium, 66% were found to have chronic beryllium disease as well. The rate of progression from beryllium sensitization to chronic beryllium disease has been estimated to be approximately 6–8% per year. Stopping exposure to beryllium in those sensitized has not been definitively shown to stop the progression to chronic beryllium disease.
4261: 350:. Relevant occupations are those where beryllium is mined, processed or converted into metal alloys, or where machining of metals containing beryllium and recycling of scrap alloys occurs. It is associated with aerospace manufacturing, microwave semiconductor electronics, beryllium mining or manufacturing of fluorescent light bulbs (which once contained beryllium compounds in their internal phosphor coating). 4290: 326:
with elevated number of cells are considered abnormal. Those exposed persons with two abnormal BeLPT tested with peripheral blood, or one abnormal and one borderline result, are considered beryllium sensitized. Also, those with one abnormal BeLPT tested with fluid from a bronchial alveolar lavage are considered sensitized.
1002:
Balmes, John R.; Abraham, Jerrold L.; Dweik, Raed A.; Fireman, Elizabeth; Fontenot, Andrew P.; Maier, Lisa A.; Muller-Quernheim, Joachim; Ostiguy, Gaston; Pepper, Lewis D. (2014). "An Official American Thoracic Society Statement: Diagnosis and Management of Beryllium Sensitivity and Chronic Beryllium
428:
The general population is unlikely to develop acute or chronic beryllium disease because ambient air levels of beryllium are normally very low (<0.03 ng/m). However, a study found 1% of people living within 3/4 of a mile of a beryllium plant in Lorain, Ohio, had berylliosis after exposure to
325:
The beryllium lymphocyte proliferation test (BeLPT) is the standard way of determining sensitivity to beryllium. The test is performed by acquiring either peripheral blood or fluid from a bronchial alveolar lavage, and lymphocytes are cultured with beryllium sulfate. Cells are then counted and those
421:
The rate of workers becoming sensitized to beryllium varies based on genetics and exposure levels. In one study researchers found the prevalence of beryllium sensitization to range from 9–19% depending on the industry. Many workers who are found to be sensitive to beryllium also meet the diagnostic
375:
On 29 January 2009, the Los Alamos National Laboratory announced it was notifying nearly 2,000 current and former employees and visitors that they may have been exposed to beryllium in the lab and may be at risk of disease. Concern over possible exposure to the material was first raised in November
337:
have been reported. Findings on CT are also not specific to berylliosis. Findings that are common in CT scans of people with berylliosis include parenchymal nodules in early stages. One study found that ground-glass opacities were more commonly seen on CT scan in berylliosis than in sarcoidosis. In
437:
Since the 1920s, beryllium has been used in electronics, ceramics, research and development labs, aircraft, and the atomic energy and defense industry. Cases of bronchitis and pneumonia-like symptoms were reported in Germany and Russia in the 1930s among workers mining and refining beryllium. By
429:
concentrations estimated to be less than 1 milligram per cubic metre of air. In the United States the Beryllium Case Registry contained 900 records, early cases relating to extraction and fluorescent lamp manufacture, later ones coming from the aerospace, ceramics and metallurgical industries.
109:. Of note, the authors of a 2006 study suggested that beryllium inhalation was not the only form of exposure and perhaps skin exposure was also a cause, as they found that a reduction in beryllium inhalation did not result in a reduction in chronic beryllium disease or beryllium sensitization. 367:
Because it can be difficult to control industrial exposures to beryllium, it is advisable to use any methods possible to reduce airborne and surface contamination by beryllium, to minimize the use of beryllium and beryllium-containing alloys whenever possible, and to educate people about the
321:
The radiologic and pathologic features of berylliosis are very similar to sarcoidosis. Due to the strong clinical and histopathological resemblance of sarcoidosis and berylliosis, patients are sometimes misdiagnosed with sarcoidosis until the history of exposure to beryllium is elicited and
438:
1946, a cluster of cases associated with fluorescent lamp manufacturers were apparent in the United States, and the lamp industry stopped using beryllium in 1949. At that time, most construction trades and industries were unaware of the potential risks associated with beryllium exposure.
104:
With single or prolonged exposure by inhalation the lungs may become sensitized to beryllium. Berylliosis has a slow onset and progression. Some people who are sensitized to beryllium may not have symptoms. Continued exposure causes the development of small inflammatory nodules, called
456:
began screening employees using the BeLPT test in facilities where beryllium was used, to take preventive measures against beryllium exposure. Somewhat alarmingly, clerical staff who were never involved in handling the material had developed asymptomatic sensitivities.
417:
The number of workers in the United States exposed to beryllium vary but has been estimated to be as high as 800,000 during the 1960s and 1970s. A more recent study from 2004 estimated the number of exposed workers in the United States to be around 134,000.
219:
allele found that CD4 T-cells do not detect the Be+ cation itself, but instead detect surface changes in the HLA-DP2/peptide complex in which Be+ is embedded. Those researchers concluded that chronic beryllium disease is a predisposition that lies between
354:
was used in lamp manufacture because of ceramic's obvious virtues for insulation and heat resistance, and also because beryllia could be made transparent. Certain welding anodes along with other electrical contacts and even non-sparking tools are made of
2191: 2176: 3931: 3866: 448:
Beryllium sensitivity testing was first performed as a cutaneous beryllium patch test in the early 1950s, but was discontinued due to the test stimulating sensitization or aggravating existing chronic beryllium disease.
1909:
Henneberger, P. K.; Cumro, D.; Deubner, D. D.; Kent, M. S.; McCawley, M.; Kreiss, K. (2001-04-01). "Beryllium sensitization and disease among long-term and short-term workers in a beryllium ceramics plant".
3553: 683:
Freiman, D. G.; Hardy, H. L. (1970-03-01). "Beryllium disease. The relation of pulmonary pathology to clinical course and prognosis based on a study of 130 cases from the U.S. beryllium case registry".
921:
Individuals carrying the MHCII allele, HLA-DP2, are at risk for chronic beryllium disease (CBD), a debilitating inflammatory lung condition caused by the reaction of CD4 T cells to inhaled beryllium.
196:
by macrophages, the beryllium triggers macrophage apoptosis, thereby reducing beryllium clearance from the lungs and eventually resulting in secondary necrosis and lysis. Eventually, the outcome is
387:
Although the evidence that stopping exposure to beryllium decreases progression of the disease is limited, it is still considered to be an accepted approach to treatment in any stage of disease.
180:
In susceptible persons, beryllium exposure can lead to a cell-mediated immune response. The T-cells become sensitized to beryllium. Each subsequent exposure leads to an immune response involving
2717: 329:
Chest radiography findings of berylliosis are non-specific. Early in the disease radiography findings are usually normal. In later stages interstitial fibrosis, pleural irregularities, hilar
838:
Rosenman KD, Rossman M, Hertzberg V, Reilly MJ, Rice C, Kanterakis E, Monos D (2011). "HLA class II DPB1 and DRB1 polymorphisms associated with genetic susceptibility to beryllium toxicity".
390:
People with early stages of disease, without lung function abnormalities or clinical symptoms, are periodically monitored with physical exams, pulmonary function testing and radiography.
3431: 601:
Kreider, ME; Rossman, MD (2015). "Chapter 87: Chronic beryllium disease and hard-metal lung diseases". In Grippi, MA; Elias, JA; Fishman, JA; Kotloff, RM; Pack, AI; Senior, RM (eds.).
4743: 372:
preparation equipment to prevent accumulation of dry particles. Sectioning, grinding, and polishing must be performed under sufficiently vented hoods equipped with special filters.
4281: 3889: 2018: 1427:
Batich, Ray and James M. Marder. (1985) Beryllium In (Ed. 9), Metals Handbook: Metallography and Microstructures (pp. 389–391). Metals Park, Ohio: American Society for Metals.
626:
Falta, Michael T.; Pinilla, Clemencia; Mack, Douglas G.; Tinega, Alex N.; Crawford, Frances; Giulianotti, Marc; Santos, Radleigh; Clayton, Gina M.; Wang, Yuxiao (2013-07-01).
1163:
Aronchick, J. M.; Rossman, M. D.; Miller, W. T. (1987-06-01). "Chronic beryllium disease: diagnosis, radiographic findings, and correlation with pulmonary function tests".
727:
Sawyer, Richard T.; Maier, Lisa A.; Kittle, Lori A.; Newman, Lee S. (February 2002). "Chronic beryllium disease: a model interaction between innate and acquired immunity".
4075: 3860: 933: 4276: 3910: 3872: 172:
The onset of symptoms can range from weeks up to tens of years from the initial exposure. In some individuals, a single exposure to beryllium can cause berylliosis.
3920: 3816: 2336: 4181: 4753: 4328: 3884: 3834: 3181: 3424: 425:
The overall prevalence of chronic beryllium disease among workers exposed to beryllium has ranged from 1–5% depending on industry and time period of study.
203:
Several studies have shown that there is a genetic component to beryllium sensitivity. Specifically, those beryllium-exposed workers with a mutation at the
232: 322:
beryllium hypersensitivity demonstrated with specific testing. Some studies suggest that up to 6% of all cases of sarcoidosis are actually berylliosis.
1823:
Kreiss, K.; Mroz, M. M.; Zhen, B.; Martyny, J. W.; Newman, L. S. (1993-10-01). "Epidemiology of beryllium sensitization and disease in nuclear workers".
1866:
Newman, Lee S.; Mroz, Margaret M.; Balkissoon, Ronald; Maier, Lisa A. (2005-01-01). "Beryllium Sensitization Progresses to Chronic Beryllium Disease".
2936: 4265: 4054: 3417: 2960: 2732: 2253: 4294: 4241: 4100: 3513: 2707: 2305: 1980: 1360: 1065:
Cheva, Angeliki; Kilmpasani, Maria; Stathakis, Eustathios; Dimitriadis, Ioannis; Mpikos, Vasileios; Papaemmanouil, Styliani (November 2016).
610: 1969:
National Research Council (U.S.). Committee on Beryllium Alloy Exposures, National Research Council (U.S.). Committee on Toxicology (2007).
4221: 881:
Clayton GM, Wang Y, Crawford F, Novikov A, Wimberly BT, Kieft JS, Falta MT, Bowerman NA, Marrack P, Fontenot AP, Dai S, Kappler JW (2014).
302:
Diagnosis of berylliosis is based on history of beryllium exposures, documented beryllium sensitivity, and granulomatous inflammation on
3503: 3393: 3176: 2931: 2329: 4171: 3186: 2982: 2268: 453: 188:
accumulating in the lungs. As this response continues macrophages, CD4+ T-lymphocytes and plasma cells aggregate together to form the
1705:"Industries in the United States with Airborne Beryllium Exposure and Estimates of the Number of Current Workers Potentially Exposed" 207:
Glu position have increased prevalence of beryllium sensitization and chronic beryllium disease. The HLA-DPB1 gene is important for
4094: 4084: 3839: 3383: 3163: 2663: 2358: 2353: 2022: 2004: 306:. Given the invasive nature of a lung biopsy, diagnosis can also be based on clinical history consistent with berylliosis, abnormal 279: 236: 4519: 3127: 1262:
since 1949 GE lamps used relatively inert phosphates found to be safe in ordinary handling of either the intact or broken lamp.
550:
Day, GA; Stefaniak, AB; Weston, A; Tinkle, SS (February 2006). "Beryllium exposure: dermal and immunological considerations".
4758: 4414: 4271: 4136: 3791: 3440: 3398: 2322: 393:
Once clinical symptoms or significant abnormalities in pulmonary function testing appear, treatments include oxygen and oral
3528: 2864: 1970: 4692: 4007: 3760: 2972: 286: 4314: 4049: 3982: 3735: 3523: 3171: 3122: 2955: 2893: 291: 4321: 4748: 4186: 3878: 3786: 3750: 3588: 3132: 247: 384:
There is no cure for berylliosis; the goals of treatment are to reduce symptoms and slow the progression of disease.
4717: 4246: 4151: 3925: 3628: 3318: 2277: 1437: 315: 4572: 3844: 3755: 3740: 3598: 3573: 3191: 2816: 2790: 2515: 2416: 2259:
CDC – Research on Beryllium Sensitization and Chronic Beryllium Disease – NIOSH Workplace Safety and Health Topic
90: 86: 2967: 2273: 1668:
Cullen, Mark; Cherniack, Martin; Kominsky, John (1986-01-01). "Chronic Beryllium Disease in the United States".
4161: 4141: 4034: 3648: 2795: 2780: 2773: 2678: 2639: 2586: 2564: 2522: 2450: 2206: 1510:
Seidler, A.; Euler, U.; MΓΌller-Quernheim, J.; Gaede, K. I.; Latza, U.; Groneberg, D.; Letzel, S. (2012-10-01).
128: 4236: 3658: 3623: 2946: 2043:
Welch, L (2013). "Beryllium Disease Among Construction Trade Workers at Department of Energy Nuclear Sites".
4206: 3992: 3095: 2737: 2653: 2528: 212: 1324:
Hardy, HL; Tabershaw, IR (1946). "Delayed chemical pneumonitis in workers exposed to beryllium compounds".
4584: 3801: 3781: 3568: 3538: 3221: 3074: 3035: 2950: 2903: 2602: 2445: 4524: 4399: 3796: 2483: 2455: 2258: 927: 628:"Identification of beryllium-dependent peptides recognized by CD4+ T cells in chronic beryllium disease" 368:
potential hazards if they are likely to encounter beryllium dust or fumes. It is important to damp wipe
1703:
Henneberger, Paul K.; Goe, Sandra K.; Miller, William E.; Doney, Brent; Groce, Dennis W. (2004-10-01).
89:, which became rare following occupational exposure limits established around 1950. Berylliosis is an 4697: 4409: 4369: 4359: 4354: 3997: 3972: 3776: 3693: 3543: 3533: 3493: 3448: 3100: 3052: 3040: 2854: 2812: 2411: 1919: 1129: 1038:
Rossman, MD; Kreider, ME (June 2003). "Is chronic beryllium disease sarcoidosis of known etiology?".
559: 347: 334: 1765:"Risks of beryllium disease related to work processes at a metal, alloy, and oxide production plant" 376:
2008, when a box containing beryllium was received at the laboratory's short-term storage facility.
36: 4567: 4534: 4494: 4394: 4131: 4014: 4002: 3967: 3745: 3730: 3723: 3703: 3473: 3455: 3368: 3335: 3081: 3030: 2658: 2478: 2345: 2195: 883:"Structural Basis of Chronic Beryllium Disease: Linking Allergic Hypersensitivity and Autoimmunity" 442: 143: 82: 1116:
Frome, Edward L; Newman, Lee S; Cragle, Donna L; Colyer, Shirley P; Wambach, Paul F (2003-02-01).
251:
X-ray image of a 54-year-old man working in the aerospace manufacturing industry with berylliosis
4738: 4702: 4661: 4486: 4364: 4166: 4070: 3987: 3806: 3226: 3091: 3047: 2879: 2800: 2727: 2597: 2140: 1951: 1740: 1685: 1632: 863: 583: 398: 132: 2103: 4671: 4641: 4609: 4604: 4589: 4562: 4509: 4499: 4404: 4384: 4379: 4349: 4216: 4029: 3708: 3683: 3578: 3563: 3348: 2592: 2421: 2382: 2301: 2297: 2290: 2285: 2132: 2060: 2000: 1976: 1943: 1935: 1891: 1883: 1848: 1840: 1802: 1784: 1732: 1724: 1650: 1593: 1541: 1533: 1487: 1410: 1356: 1333: 1306: 1226: 1188: 1180: 1145: 1088: 1047: 1020: 977: 912: 855: 801: 793: 752: 744: 709: 701: 665: 647: 606: 575: 532: 49: 968:
Newman, LS (March 1995). "Beryllium disease and sarcoidosis: clinical and laboratory links".
515:
Kriebel, D; Brain, JD; Sprince, NL; Kazemi, H (1988). "The pulmonary toxicity of beryllium".
216: 4636: 4594: 3957: 3952: 3618: 3558: 3291: 3284: 3148: 3069: 2908: 2844: 2693: 2124: 2052: 1927: 1875: 1832: 1792: 1776: 1716: 1677: 1640: 1624: 1583: 1575: 1523: 1477: 1469: 1400: 1392: 1296: 1286: 1218: 1172: 1137: 1096: 1078: 1012: 902: 894: 847: 783: 736: 693: 655: 639: 567: 524: 356: 338:
later stages hilar lymphadenopathy, interstitial pulmonary fibrosis and pleural thickening.
307: 947: 4707: 4599: 4539: 4504: 4389: 4374: 4231: 4211: 4039: 3718: 3713: 3313: 3265: 3153: 3104: 3025: 2941: 2749: 330: 3668: 1209:
Sharma, Nidhi; Patel, Jeet; Mohammed, Tan-Lucien H. (2010). "Chronic Beryllium Disease".
494: 480: 1923: 1512:"Systematic review: progression of beryllium sensitization to chronic beryllium disease" 1133: 563: 4651: 4646: 4631: 4619: 4196: 4156: 4044: 4024: 4019: 3638: 3603: 3518: 3251: 2913: 2824: 2744: 2554: 2549: 2078: 1797: 1764: 1645: 1612: 1588: 1563: 1482: 1457: 1405: 1380: 1301: 1274: 1101: 1066: 907: 882: 772:"Immunogenetic basis of environmental lung disease: lessons from the berylliosis model" 660: 627: 394: 369: 273: 1141: 740: 697: 359:
alloy and the subsequent machining of such materials would cause the disease as well.
4732: 4712: 4676: 4666: 4624: 4614: 4201: 3962: 3663: 3608: 3343: 3057: 2768: 2314: 1244: 181: 2200: 2144: 1955: 1836: 1744: 1689: 1176: 867: 823:
Beryllium Toxicity: How Should Patients Exposed to Beryllium Be Treated and Managed?
587: 4529: 4116: 4090: 4080: 3673: 3613: 3583: 3280: 3233: 2618: 2570: 2439: 770:
Saltini, C.; Amicosante, M.; Franchi, A.; Lombardi, G.; Richeldi, L. (1998-12-01).
267: 225: 208: 193: 113: 2235: 2128: 1067:"AB042. Sarcoidosis or Berylliosis? Two diseases with similar histologic findings" 3409: 2211: 1222: 788: 771: 4514: 4126: 3593: 3488: 3378: 3325: 3308: 3303: 3256: 3211: 3062: 3010: 2977: 2578: 2510: 2473: 2428: 2363: 2099: 303: 259: 155: 151: 117: 54: 2115:
Marshall, E (1999). "Science News: Beryllium screening raises ethical issues".
1016: 528: 4465: 4226: 4176: 4146: 4121: 3643: 3633: 3508: 3498: 3478: 3468: 3298: 2898: 2884: 2859: 2834: 2829: 2763: 2712: 2634: 2610: 2559: 2433: 2398: 2373: 2185: 1879: 1720: 1613:"The natural history of beryllium sensitization and chronic beryllium disease" 1473: 571: 185: 147: 106: 1939: 1887: 1844: 1788: 1728: 1537: 1184: 1092: 797: 748: 705: 651: 215:. A study of the immune response to beryllium in individuals who express the 3947: 3915: 3653: 3463: 3373: 3005: 2874: 2869: 2839: 2390: 2230: 1528: 1511: 1291: 1083: 851: 189: 121: 78: 2249: 2136: 2064: 1947: 1895: 1736: 1681: 1579: 1545: 1491: 1337: 1310: 1230: 1149: 1051: 1024: 916: 898: 859: 822: 756: 669: 579: 1931: 1852: 1806: 1763:
Kreiss, K.; Mroz, M. M.; Zhen, B.; Wiedemann, H.; Barna, B. (1997-08-01).
1654: 1597: 1414: 1192: 981: 805: 713: 536: 4656: 4549: 4457: 4441: 4191: 3678: 3548: 3388: 3273: 2673: 2406: 1780: 1396: 643: 351: 204: 197: 441:
It occasionally killed early workers in nuclear weapons design, such as
4557: 2626: 2502: 2292:
Dying for work: workers' safety and health in twentieth-century America
2056: 1636: 1118:"Identification of an abnormal beryllium lymphocyte proliferation test" 311: 221: 74: 4306: 3867:
Istituto nazionale per l'assicurazione contro gli infortuni sul lavoro
2263: 2168: 4473: 4449: 4433: 4424: 3977: 2723: 2536: 2465: 2180: 2081:. Office of Public Affairs, Argonne National Laboratory. 19 June 2006 296: 1704: 1628: 1117: 1351:
Cayless, M A; Marsden, A M, eds. (1983). "7.2.1 Optical ceramics".
2544: 246: 166: 159: 139: 2098:
Agency for Toxic Substances and Disease Registry. September 2002
124:, and so distinction between the two processes can be difficult. 2493: 2250:
ATSDR Case Studies in Environmental Medicine: Beryllium Toxicity
4310: 3413: 2318: 1912:
International Archives of Occupational and Environmental Health
552:
International Archives of Occupational and Environmental Health
821:
Agency for Toxic Substances and Disease Registry via the CDC.
165:
Rarely, one can get granulomas in other organs including the
73:), is a chronic allergic-type lung response and chronic lung 1438:"Nearly 2,000 people warned of possible beryllium exposure" 2280:
examining the molecular basis of chronic beryllium disease
1868:
American Journal of Respiratory and Critical Care Medicine
1005:
American Journal of Respiratory and Critical Care Medicine
1279:
Indian Journal of Occupational and Environmental Medicine
2286:"Ch. 7: Salem Sarcoid:The Origins of Beryllium Disease" 1557: 1555: 44:
Peribronchal non-necrotizing granuloma from berylliosis
112:
Granuloma formation is seen in other diseases such as
3890:
National Institute for Occupational Safety and Health
2284:
Rosner, David; Markowitz, Gerald E. (February 1987).
1564:"Chronic beryllium disease: diagnosis and management" 1275:"The uses and adverse effects of beryllium on health" 255:
The differential diagnosis for berylliosis includes:
2158: 1273:
Cooper, Ross G.; Harrison, Adrian P. (August 2009).
239:; they are carcinogenic to both animals and humans. 4685: 4548: 4485: 4423: 4342: 4109: 4063: 3940: 3903: 3853: 3827: 3815: 3769: 3692: 3447: 3361: 3334: 3264: 3250: 3204: 3162: 3141: 3115: 3018: 3004: 2995: 2924: 2809: 2789: 2672: 2652: 2492: 2372: 2352: 2221: 2162: 950:. International Agency for Research on Cancer. 1993 475: 473: 471: 469: 48: 26: 21: 4076:Occupational Safety and Health Act (United States) 3861:Canadian Centre for Occupational Health and Safety 2289: 1670:Seminars in Respiratory and Critical Care Medicine 817: 815: 1709:Journal of Occupational and Environmental Hygiene 1462:Journal of Occupational and Environmental Hygiene 1040:Sarcoidosis, Vasculitis and Diffuse Lung Diseases 96:While there is no cure, symptoms can be treated. 3873:National Institute for Safety and Health at Work 2079:"Photograph of Chicago Pile One Scientists 1946" 1458:"Current Treatment of Chronic Beryllium Disease" 3921:Occupational Safety and Health Convention, 1981 120:. Sarcoidosis, like berylliosis, also produces 833: 831: 4744:Biology and pharmacology of chemical elements 4322: 3885:Occupational Safety and Health Administration 3835:European Agency for Safety and Health at Work 3425: 2330: 932:: CS1 maint: DOI inactive as of April 2024 ( 8: 1355:(3rd ed.). Edward Arnold. p. 127. 1326:Journal of Industrial Hygiene and Toxicology 233:International Agency for Research on Cancer 4329: 4315: 4307: 3824: 3529:Coalworker's pneumoconiosis ("black lung") 3432: 3418: 3410: 3261: 3015: 3001: 2806: 2669: 2369: 2337: 2323: 2315: 2159: 1825:The American Review of Respiratory Disease 1818: 1816: 1611:Newman, LS; Lloyd, J; Daniloff, E (1996). 1505: 1503: 1501: 603:Fishman's Pulmonary Diseases and Disorders 517:The American Review of Respiratory Disease 35: 18: 2937:Combined pulmonary fibrosis and emphysema 1796: 1758: 1756: 1754: 1644: 1587: 1527: 1481: 1404: 1300: 1290: 1204: 1202: 1100: 1082: 906: 787: 659: 495:"Berylliosis: Treatment & Medication" 1975:. National Academies Press. p. 11. 235:, beryllium and beryllium compounds are 4055:Immediately dangerous to life or health 2961:Allergic bronchopulmonary aspergillosis 2254:Department of Health and Human Services 2045:American Journal of Industrial Medicine 1769:Occupational and Environmental Medicine 1451: 1449: 1447: 1374: 1372: 1211:Journal of Computer Assisted Tomography 465: 4242:Workplace hazard controls for COVID-19 3514:Chronic solvent-induced encephalopathy 1995:David Geraint James, Alimuddin Zumla, 997: 995: 993: 991: 925: 2296:. Indiana University Press. pp.  7: 4754:Lung diseases due to external agents 4289: 3932:Working Environment Convention, 1977 1999:, Cambridge University Press, 1999, 1972:Health effects of beryllium exposure 632:The Journal of Experimental Medicine 138:The earliest symptoms are typically 4427: (Core six elements) 4101:Workers' right to access the toilet 3394:Idiopathic pulmonary haemosiderosis 409:Overall mortality rates are 5–38%. 4172:International Chemical Safety Card 2983:Vaping-associated pulmonary injury 2346:Diseases of the respiratory system 127:Ultimately, this process leads to 122:granulomas without a necrotic core 14: 4182:National Day of Mourning (Canada) 3840:International Labour Organization 2017:Brown University Medical School. 1617:Environmental Health Perspectives 1568:Environmental Health Perspectives 1385:Environmental Health Perspectives 1260:, Dec. 1978, says on pg. 23 that 4288: 4260: 4259: 2100:Toxicological Profile: Beryllium 1071:Annals of Translational Medicine 729:International Immunopharmacology 280:Granulomatosis with polyangiitis 1379:Lang, Leslie (June–July 1994). 1177:10.1148/radiology.163.3.3575713 825:Page last updated: May 23, 2008 314:findings, and abnormalities in 30:Chronic beryllium disease (CBD) 4415:Biological aspects of fluorine 4137:Environment, health and safety 3792:Occupational health psychology 3441:Occupational safety and health 3399:Pulmonary alveolar proteinosis 1381:"Beryllium: A Chronic Problem" 1: 4693:Composition of the human body 4008:Personal protective equipment 3761:Workplace health surveillance 2973:Idiopathic pulmonary fibrosis 2129:10.1126/science.285.5425.178b 1837:10.1164/ajrccm/148.4_Pt_1.985 1142:10.1016/S0300-483X(02)00439-0 741:10.1016/S1567-5769(01)00177-1 698:10.1016/S0046-8177(70)80003-X 605:(5th ed.). McGraw-Hill. 287:Idiopathic pulmonary fibrosis 81:and its compounds, a form of 4050:Standard operating procedure 3983:Hierarchy of hazard controls 3736:Hierarchy of hazard controls 2956:Respiratory hypersensitivity 2894:Hypersensitivity pneumonitis 1223:10.1097/rct.0b013e3181ef214e 789:10.1183/09031936.98.12061463 776:European Respiratory Journal 493:Dweik, Raed A (2008-11-19). 483:Page accessed March 29, 2016 292:Hypersensitivity pneumonitis 264:Granulomatous lung diseases 4703:Mineral (Essential element) 4187:NIOSH air filtration rating 3879:Health and Safety Executive 3787:Occupational health nursing 3751:Occupational exposure limit 3589:Hospital-acquired infection 3554:Exposure to human nail dust 2865:Coalworker's pneumoconiosis 1997:The granulomatous disorders 948:"IARC Monograph, Volume 58" 4775: 4718:Uranium in the environment 4247:Workplace health promotion 4152:Hawks Nest Tunnel disaster 3926:Worker Protection Standard 3629:Noise-induced hearing loss 2718:Acute exacerbation of COPD 2278:Royal Society of Chemistry 1017:10.1164/rccm.201409-1722st 4573:Acute beryllium poisoning 4255: 3845:World Health Organization 3756:Occupational epidemiology 3741:Prevention through design 3599:Laboratory animal allergy 3524:Chimney sweeps' carcinoma 3499:Byssinosis ("brown lung") 1880:10.1164/rccm.200402-190OC 1721:10.1080/15459620490502233 1474:10.1080/15459620903158698 1258:Fluorescent Lamps TP 111R 572:10.1007/s00420-005-0024-0 272:Fungal infections (e.g., 222:allergic hypersensitivity 182:CD4+ helper T-lymphocytes 146:. Other symptoms include 91:occupational lung disease 87:acute beryllium poisoning 67:chronic beryllium disease 43: 34: 4162:Hostile work environment 4142:Environmental toxicology 4035:Redundancy (engineering) 3649:Repetitive strain injury 2781:Diffuse panbronchiolitis 2774:Bronchiolitis obliterans 2640:Laryngotracheal stenosis 2587:Laryngopharyngeal reflux 2565:Laryngopharyngeal reflux 2523:Laryngopharyngeal reflux 2451:Nasal septum perforation 529:10.1164/ajrccm/137.2.464 481:Beryllium Health Effects 316:pulmonary function tests 213:antigen presenting cells 129:restrictive lung disease 4207:Quality of working life 3993:Administrative controls 2529:Retropharyngeal abscess 1440:. CNN. 29 January 2009. 1292:10.4103/0019-5278.55122 1084:10.21037/atm.2016.AB042 901:(inactive 2024-04-15). 852:10.1136/oem.2010.055046 190:noncaseating granulomas 4585:Chlorine gas poisoning 3802:Occupational therapist 3782:Industrial engineering 3574:Glassblower's cataract 3539:Decompression sickness 3222:Pulmonary hypertension 2951:Eosinophilic pneumonia 2603:Vocal cord dysfunction 2446:Nasal septum deviation 1682:10.1055/s-2007-1012616 1580:10.1289/ehp.96104s5945 1245:ToxGuide for Beryllium 899:10.1016/j.cell.2014.04 335:ground-glass opacities 252: 237:Category 1 carcinogens 85:. It is distinct from 77:caused by exposure to 4759:Occupational diseases 4558:Argyria (Silver) 4400:Molybdenum in biology 4272:Occupational diseases 4237:Workers' compensation 3797:Occupational medicine 3659:Silo-filler's disease 3624:Mule spinners' cancer 3349:Mediastinal emphysema 3128:Healthcare-associated 3058:Legionnaires' disease 2484:Peritonsillar abscess 2456:Nasal septal hematoma 1932:10.1007/s004200100237 1529:10.1093/occmed/kqs069 1516:Occupational Medicine 1456:Sood, Akshay (2009). 250: 211:molecule function on 4698:Lithium (medication) 4410:Arsenic biochemistry 4370:Manganese in biology 4360:Potassium in biology 4355:Magnesium in biology 3998:Engineering controls 3973:Emergency evacuation 3777:Environmental health 3544:De Quervain syndrome 3534:Concussions in sport 3096:Mendelson's syndrome 2968:Hamman–Rich syndrome 1781:10.1136/oem.54.8.605 1574:(Suppl 5): 945–947. 1397:10.1289/ehp.94102526 644:10.1084/jem.20122426 348:occupational disease 192:. When beryllium is 4568:Beryllium poisoning 4395:Selenium in biology 4337:Elements in biology 4132:Effects of overtime 4015:Job safety analysis 4003:Hazard substitution 3968:Emergency procedure 3746:Exposure assessment 3731:Occupational stress 3724:Psychosocial hazard 3704:Occupational hazard 3569:Flock worker's lung 3369:Respiratory failure 3336:Mediastinal disease 2904:Bird fancier's lung 2479:Adenoid hypertrophy 1924:2001IAOEH..74..167H 1831:(4 Pt 1): 985–991. 1623:(Suppl 5): 937–43. 1562:Rossman, M (1996). 1134:2003Toxgy.183...39F 564:2006IAOEH..79..161D 443:Herbert L. Anderson 144:shortness of breath 83:beryllium poisoning 4749:Element toxicology 4662:Thallium poisoning 4365:Calcium in biology 4167:Indoor air quality 4071:Diving regulations 3988:Hazard elimination 3807:Safety engineering 3274:Pleuritis/pleurisy 3227:Pulmonary embolism 3123:Community-acquired 3048:Atypical bacterial 2947:LΓΆffler's syndrome 2728:Status asthmaticus 2713:Chronic bronchitis 2598:Vocal fold paresis 2412:Vasomotor rhinitis 2222:External resources 2057:10.1002/ajim.22202 1353:Lamps and Lighting 452:In the 1990s, the 399:supportive therapy 346:Berylliosis is an 253: 133:diffusion capacity 100:Signs and symptoms 4726: 4725: 4672:Toxic heavy metal 4657:Selenium toxicity 4642:Mercury poisoning 4610:Fluoride toxicity 4605:Cadmium poisoning 4590:Chromium toxicity 4563:Arsenic poisoning 4405:Iodine in biology 4385:Copper in biology 4380:Cobalt in biology 4350:Sodium in biology 4304: 4303: 4217:Safety data sheet 4030:Operations manual 3911:Bangladesh Accord 3899: 3898: 3709:Biological hazard 3407: 3406: 3357: 3356: 3314:Empyema/pyothorax 3246: 3245: 3242: 3241: 3200: 3199: 3133:Hospital-acquired 2991: 2990: 2855:Caplan's syndrome 2648: 2647: 2593:Vocal fold nodule 2417:Atrophic rhinitis 2307:978-0-253-31825-1 2264:Beryllium Network 2245: 2244: 2123:(5425): 178–179. 2051:(10): 1125–1136. 1982:978-0-309-11167-6 1362:978-0-7131-3487-2 1256:General Electric 840:Occup Environ Med 612:978-0-07-179672-9 231:According to the 60: 59: 16:Medical condition 4766: 4637:Lithium toxicity 4595:Cobalt poisoning 4331: 4324: 4317: 4308: 4292: 4291: 4263: 4262: 3958:Contingency plan 3953:Code of practice 3825: 3619:Metal fume fever 3434: 3427: 3420: 3411: 3292:Pleural effusion 3285:Hemopneumothorax 3262: 3016: 3002: 2845:Bauxite fibrosis 2810:External agents/ 2807: 2738:Exercise-induced 2694:Acute bronchitis 2670: 2370: 2339: 2332: 2325: 2316: 2311: 2295: 2269:Health-cares.net 2160: 2149: 2148: 2112: 2106: 2096: 2090: 2089: 2087: 2086: 2075: 2069: 2068: 2040: 2034: 2033: 2031: 2030: 2021:. Archived from 2014: 2008: 1993: 1987: 1986: 1966: 1960: 1959: 1906: 1900: 1899: 1863: 1857: 1856: 1820: 1811: 1810: 1800: 1760: 1749: 1748: 1700: 1694: 1693: 1665: 1659: 1658: 1648: 1608: 1602: 1601: 1591: 1559: 1550: 1549: 1531: 1507: 1496: 1495: 1485: 1453: 1442: 1441: 1434: 1428: 1425: 1419: 1418: 1408: 1376: 1367: 1366: 1348: 1342: 1341: 1321: 1315: 1314: 1304: 1294: 1270: 1264: 1254: 1248: 1241: 1235: 1234: 1206: 1197: 1196: 1160: 1154: 1153: 1113: 1107: 1106: 1104: 1086: 1062: 1056: 1055: 1035: 1029: 1028: 999: 986: 985: 965: 959: 958: 956: 955: 944: 938: 937: 931: 923: 910: 878: 872: 871: 835: 826: 819: 810: 809: 791: 782:(6): 1463–1475. 767: 761: 760: 735:(2–3): 249–261. 724: 718: 717: 680: 674: 673: 663: 638:(7): 1403–1418. 623: 617: 616: 598: 592: 591: 547: 541: 540: 512: 506: 505: 503: 502: 490: 484: 477: 357:beryllium copper 39: 19: 4774: 4773: 4769: 4768: 4767: 4765: 4764: 4763: 4729: 4728: 4727: 4722: 4708:Oxygen toxicity 4681: 4600:Copper toxicity 4544: 4481: 4419: 4390:Zinc in biology 4375:Iron in biology 4338: 4335: 4305: 4300: 4251: 4232:Toxic workplace 4212:Risk management 4105: 4059: 4040:Risk assessment 3936: 3895: 3849: 3820: 3811: 3765: 3719:Physical hazard 3714:Chemical hazard 3695: 3688: 3453: 3450: 3443: 3438: 3408: 3403: 3353: 3330: 3266:Pleural disease 3255: 3238: 3196: 3158: 3142:By distribution 3137: 3116:By vector/route 3111: 3009: 2997: 2987: 2942:Pulmonary edema 2920: 2815: 2811: 2798: 2794: 2785: 2750:Cystic fibrosis 2677: 2661: 2657: 2644: 2488: 2362: 2356: 2348: 2343: 2308: 2283: 2274:Instant insight 2246: 2241: 2240: 2217: 2216: 2171: 2157: 2152: 2114: 2113: 2109: 2097: 2093: 2084: 2082: 2077: 2076: 2072: 2042: 2041: 2037: 2028: 2026: 2016: 2015: 2011: 2007:, pages 336–337 1994: 1990: 1983: 1968: 1967: 1963: 1908: 1907: 1903: 1865: 1864: 1860: 1822: 1821: 1814: 1762: 1761: 1752: 1715:(10): 648–659. 1702: 1701: 1697: 1667: 1666: 1662: 1629:10.2307/3433014 1610: 1609: 1605: 1561: 1560: 1553: 1509: 1508: 1499: 1468:(12): 762–765. 1455: 1454: 1445: 1436: 1435: 1431: 1426: 1422: 1391:(6–7): 526–31. 1378: 1377: 1370: 1363: 1350: 1349: 1345: 1323: 1322: 1318: 1272: 1271: 1267: 1255: 1251: 1242: 1238: 1208: 1207: 1200: 1162: 1161: 1157: 1115: 1114: 1110: 1064: 1063: 1059: 1037: 1036: 1032: 1011:(10): e34–e59. 1001: 1000: 989: 967: 966: 962: 953: 951: 946: 945: 941: 924: 880: 879: 875: 837: 836: 829: 820: 813: 769: 768: 764: 726: 725: 721: 686:Human Pathology 682: 681: 677: 625: 624: 620: 613: 600: 599: 595: 549: 548: 544: 514: 513: 509: 500: 498: 492: 491: 487: 478: 467: 463: 435: 415: 407: 395:corticosteroids 382: 365: 344: 331:lymphadenopathy 245: 178: 131:(a decrease in 102: 17: 12: 11: 5: 4772: 4770: 4762: 4761: 4756: 4751: 4746: 4741: 4731: 4730: 4724: 4723: 4721: 4720: 4715: 4710: 4705: 4700: 4695: 4689: 4687: 4683: 4682: 4680: 4679: 4674: 4669: 4664: 4659: 4654: 4652:Nickel allergy 4649: 4647:Metal toxicity 4644: 4639: 4634: 4632:Lead poisoning 4629: 4628: 4627: 4620:Iron poisoning 4617: 4612: 4607: 4602: 4597: 4592: 4587: 4582: 4581: 4580: 4575: 4565: 4560: 4554: 4552: 4546: 4545: 4543: 4542: 4537: 4532: 4527: 4522: 4517: 4512: 4507: 4502: 4497: 4491: 4489: 4483: 4482: 4480: 4479: 4471: 4463: 4455: 4447: 4439: 4430: 4428: 4421: 4420: 4418: 4417: 4412: 4407: 4402: 4397: 4392: 4387: 4382: 4377: 4372: 4367: 4362: 4357: 4352: 4346: 4344: 4340: 4339: 4336: 4334: 4333: 4326: 4319: 4311: 4302: 4301: 4299: 4298: 4286: 4285: 4284: 4279: 4274: 4256: 4253: 4252: 4250: 4249: 4244: 4239: 4234: 4229: 4224: 4222:Source control 4219: 4214: 4209: 4204: 4199: 4197:Process safety 4194: 4189: 4184: 4179: 4174: 4169: 4164: 4159: 4157:Health physics 4154: 4149: 4144: 4139: 4134: 4129: 4124: 4119: 4113: 4111: 4107: 4106: 4104: 4103: 4098: 4088: 4078: 4073: 4067: 4065: 4061: 4060: 4058: 4057: 4052: 4047: 4045:Safety culture 4042: 4037: 4032: 4027: 4025:Permit To Work 4022: 4020:Lockout-tagout 4017: 4012: 4011: 4010: 4005: 4000: 3995: 3990: 3980: 3975: 3970: 3965: 3960: 3955: 3950: 3944: 3942: 3938: 3937: 3935: 3934: 3929: 3923: 3918: 3913: 3907: 3905: 3901: 3900: 3897: 3896: 3894: 3893: 3887: 3882: 3876: 3870: 3864: 3857: 3855: 3851: 3850: 3848: 3847: 3842: 3837: 3831: 3829: 3822: 3813: 3812: 3810: 3809: 3804: 3799: 3794: 3789: 3784: 3779: 3773: 3771: 3767: 3766: 3764: 3763: 3758: 3753: 3748: 3743: 3738: 3733: 3728: 3727: 3726: 3721: 3716: 3711: 3700: 3698: 3690: 3689: 3687: 3686: 3684:Writer's cramp 3681: 3676: 3671: 3666: 3661: 3656: 3651: 3646: 3641: 3639:Pneumoconiosis 3636: 3631: 3626: 3621: 3616: 3611: 3606: 3604:Lead poisoning 3601: 3596: 3591: 3586: 3581: 3579:Golfer's elbow 3576: 3571: 3566: 3564:Fiddler's neck 3561: 3556: 3551: 3546: 3541: 3536: 3531: 3526: 3521: 3519:Chronic stress 3516: 3511: 3506: 3504:Cardiovascular 3501: 3496: 3491: 3486: 3481: 3476: 3471: 3466: 3460: 3458: 3445: 3444: 3439: 3437: 3436: 3429: 3422: 3414: 3405: 3404: 3402: 3401: 3396: 3391: 3386: 3381: 3376: 3371: 3365: 3363: 3359: 3358: 3355: 3354: 3352: 3351: 3346: 3340: 3338: 3332: 3331: 3329: 3328: 3322: 3321: 3316: 3311: 3306: 3301: 3296: 3294: 3288: 3287: 3277: 3276: 3270: 3268: 3259: 3252:Pleural cavity 3248: 3247: 3244: 3243: 3240: 3239: 3237: 3236: 3231: 3230: 3229: 3224: 3214: 3208: 3206: 3202: 3201: 3198: 3197: 3195: 3194: 3189: 3184: 3179: 3174: 3168: 3166: 3160: 3159: 3157: 3156: 3151: 3145: 3143: 3139: 3138: 3136: 3135: 3130: 3125: 3119: 3117: 3113: 3112: 3110: 3109: 3108: 3107: 3098: 3084: 3079: 3078: 3077: 3067: 3066: 3065: 3060: 3055: 3045: 3044: 3043: 3038: 3028: 3022: 3020: 3013: 2999: 2993: 2992: 2989: 2988: 2986: 2985: 2980: 2975: 2970: 2965: 2964: 2963: 2953: 2944: 2939: 2934: 2928: 2926: 2922: 2921: 2919: 2918: 2917: 2916: 2914:Lycoperdonosis 2911: 2906: 2901: 2890: 2889: 2888: 2887: 2882: 2877: 2872: 2867: 2862: 2857: 2852: 2847: 2842: 2837: 2832: 2825:Pneumoconiosis 2821: 2819: 2804: 2787: 2786: 2784: 2783: 2778: 2777: 2776: 2766: 2761: 2759: 2753: 2752: 2747: 2745:Bronchiectasis 2742: 2741: 2740: 2735: 2730: 2721: 2715: 2705: 2703: 2697: 2696: 2691: 2689: 2683: 2681: 2667: 2650: 2649: 2646: 2645: 2643: 2642: 2637: 2632: 2630: 2622: 2621: 2616: 2614: 2606: 2605: 2600: 2595: 2590: 2584: 2582: 2574: 2573: 2568: 2562: 2557: 2555:Laryngeal cyst 2552: 2550:Laryngomalacia 2547: 2542: 2540: 2532: 2531: 2526: 2520: 2519: 2518: 2508: 2506: 2498: 2496: 2490: 2489: 2487: 2486: 2481: 2476: 2471: 2469: 2461: 2460: 2459: 2458: 2453: 2448: 2436: 2431: 2426: 2425: 2424: 2419: 2414: 2404: 2402: 2394: 2393: 2388: 2386: 2378: 2376: 2367: 2350: 2349: 2344: 2342: 2341: 2334: 2327: 2319: 2313: 2312: 2306: 2281: 2271: 2266: 2261: 2256: 2243: 2242: 2239: 2238: 2226: 2225: 2223: 2219: 2218: 2215: 2214: 2203: 2188: 2172: 2167: 2166: 2164: 2163:Classification 2156: 2155:External links 2153: 2151: 2150: 2107: 2091: 2070: 2035: 2009: 1988: 1981: 1961: 1918:(3): 167–176. 1901: 1858: 1812: 1775:(8): 605–612. 1750: 1695: 1676:(3): 203–209. 1660: 1603: 1551: 1522:(7): 506–513. 1497: 1443: 1429: 1420: 1368: 1361: 1343: 1316: 1265: 1249: 1247:September 2002 1236: 1217:(6): 945–948. 1198: 1171:(3): 677–682. 1155: 1128:(1–3): 39–56. 1108: 1057: 1030: 987: 960: 939: 893:(1): 132–142. 873: 827: 811: 762: 719: 675: 618: 611: 593: 542: 507: 485: 464: 462: 459: 434: 431: 414: 411: 406: 403: 381: 378: 370:metallographic 364: 361: 343: 342:Classification 340: 300: 299: 294: 289: 284: 283: 282: 277: 274:histoplasmosis 270: 262: 244: 241: 177: 174: 101: 98: 58: 57: 52: 46: 45: 41: 40: 32: 31: 28: 24: 23: 15: 13: 10: 9: 6: 4: 3: 2: 4771: 4760: 4757: 4755: 4752: 4750: 4747: 4745: 4742: 4740: 4737: 4736: 4734: 4719: 4716: 4714: 4713:Soil salinity 4711: 4709: 4706: 4704: 4701: 4699: 4696: 4694: 4691: 4690: 4688: 4684: 4678: 4677:Zinc toxicity 4675: 4673: 4670: 4668: 4667:Tin poisoning 4665: 4663: 4660: 4658: 4655: 4653: 4650: 4648: 4645: 4643: 4640: 4638: 4635: 4633: 4630: 4626: 4625:Iron overload 4623: 4622: 4621: 4618: 4616: 4615:Halotolerance 4613: 4611: 4608: 4606: 4603: 4601: 4598: 4596: 4593: 4591: 4588: 4586: 4583: 4579: 4576: 4574: 4571: 4570: 4569: 4566: 4564: 4561: 4559: 4556: 4555: 4553: 4551: 4547: 4541: 4538: 4536: 4533: 4531: 4528: 4526: 4523: 4521: 4518: 4516: 4513: 4511: 4508: 4506: 4503: 4501: 4498: 4496: 4493: 4492: 4490: 4488: 4484: 4478: 4476: 4472: 4470: 4468: 4464: 4462: 4460: 4456: 4454: 4452: 4448: 4446: 4444: 4440: 4438: 4436: 4432: 4431: 4429: 4426: 4422: 4416: 4413: 4411: 4408: 4406: 4403: 4401: 4398: 4396: 4393: 4391: 4388: 4386: 4383: 4381: 4378: 4376: 4373: 4371: 4368: 4366: 4363: 4361: 4358: 4356: 4353: 4351: 4348: 4347: 4345: 4341: 4332: 4327: 4325: 4320: 4318: 4313: 4312: 4309: 4297: 4296: 4287: 4283: 4282:Organizations 4280: 4278: 4275: 4273: 4270: 4269: 4268: 4267: 4258: 4257: 4254: 4248: 4245: 4243: 4240: 4238: 4235: 4233: 4230: 4228: 4225: 4223: 4220: 4218: 4215: 4213: 4210: 4208: 4205: 4203: 4202:Public health 4200: 4198: 4195: 4193: 4190: 4188: 4185: 4183: 4180: 4178: 4175: 4173: 4170: 4168: 4165: 4163: 4160: 4158: 4155: 4153: 4150: 4148: 4145: 4143: 4140: 4138: 4135: 4133: 4130: 4128: 4125: 4123: 4120: 4118: 4115: 4114: 4112: 4108: 4102: 4099: 4096: 4095:United States 4092: 4089: 4086: 4085:United States 4082: 4079: 4077: 4074: 4072: 4069: 4068: 4066: 4062: 4056: 4053: 4051: 4048: 4046: 4043: 4041: 4038: 4036: 4033: 4031: 4028: 4026: 4023: 4021: 4018: 4016: 4013: 4009: 4006: 4004: 4001: 3999: 3996: 3994: 3991: 3989: 3986: 3985: 3984: 3981: 3979: 3976: 3974: 3971: 3969: 3966: 3964: 3963:Diving safety 3961: 3959: 3956: 3954: 3951: 3949: 3946: 3945: 3943: 3939: 3933: 3930: 3927: 3924: 3922: 3919: 3917: 3914: 3912: 3909: 3908: 3906: 3902: 3891: 3888: 3886: 3883: 3880: 3877: 3874: 3871: 3868: 3865: 3862: 3859: 3858: 3856: 3852: 3846: 3843: 3841: 3838: 3836: 3833: 3832: 3830: 3828:International 3826: 3823: 3821:organizations 3818: 3814: 3808: 3805: 3803: 3800: 3798: 3795: 3793: 3790: 3788: 3785: 3783: 3780: 3778: 3775: 3774: 3772: 3768: 3762: 3759: 3757: 3754: 3752: 3749: 3747: 3744: 3742: 3739: 3737: 3734: 3732: 3729: 3725: 3722: 3720: 3717: 3715: 3712: 3710: 3707: 3706: 3705: 3702: 3701: 3699: 3697: 3694:Occupational 3691: 3685: 3682: 3680: 3677: 3675: 3672: 3670: 3667: 3665: 3664:Sports injury 3662: 3660: 3657: 3655: 3652: 3650: 3647: 3645: 3642: 3640: 3637: 3635: 3632: 3630: 3627: 3625: 3622: 3620: 3617: 3615: 3612: 3610: 3609:Low back pain 3607: 3605: 3602: 3600: 3597: 3595: 3592: 3590: 3587: 3585: 3582: 3580: 3577: 3575: 3572: 3570: 3567: 3565: 3562: 3560: 3559:Farmer's lung 3557: 3555: 3552: 3550: 3547: 3545: 3542: 3540: 3537: 3535: 3532: 3530: 3527: 3525: 3522: 3520: 3517: 3515: 3512: 3510: 3507: 3505: 3502: 3500: 3497: 3495: 3492: 3490: 3487: 3485: 3482: 3480: 3477: 3475: 3472: 3470: 3467: 3465: 3462: 3461: 3459: 3457: 3452: 3449:Occupational 3446: 3442: 3435: 3430: 3428: 3423: 3421: 3416: 3415: 3412: 3400: 3397: 3395: 3392: 3390: 3387: 3385: 3382: 3380: 3377: 3375: 3372: 3370: 3367: 3366: 3364: 3362:Other/general 3360: 3350: 3347: 3345: 3344:Mediastinitis 3342: 3341: 3339: 3337: 3333: 3327: 3324: 3323: 3320: 3317: 3315: 3312: 3310: 3307: 3305: 3302: 3300: 3297: 3295: 3293: 3290: 3289: 3286: 3282: 3279: 3278: 3275: 3272: 3271: 3269: 3267: 3263: 3260: 3258: 3253: 3249: 3235: 3232: 3228: 3225: 3223: 3220: 3219: 3218: 3215: 3213: 3210: 3209: 3207: 3203: 3193: 3190: 3188: 3185: 3183: 3180: 3178: 3175: 3173: 3170: 3169: 3167: 3165: 3161: 3155: 3152: 3150: 3147: 3146: 3144: 3140: 3134: 3131: 3129: 3126: 3124: 3121: 3120: 3118: 3114: 3106: 3102: 3099: 3097: 3093: 3090: 3089: 3088: 3087:noninfectious 3085: 3083: 3080: 3076: 3073: 3072: 3071: 3068: 3064: 3061: 3059: 3056: 3054: 3051: 3050: 3049: 3046: 3042: 3039: 3037: 3034: 3033: 3032: 3029: 3027: 3024: 3023: 3021: 3017: 3014: 3012: 3007: 3003: 3000: 2996:Obstructive / 2994: 2984: 2981: 2979: 2976: 2974: 2971: 2969: 2966: 2962: 2959: 2958: 2957: 2954: 2952: 2948: 2945: 2943: 2940: 2938: 2935: 2933: 2930: 2929: 2927: 2923: 2915: 2912: 2910: 2909:Farmer's lung 2907: 2905: 2902: 2900: 2897: 2896: 2895: 2892: 2891: 2886: 2883: 2881: 2878: 2876: 2873: 2871: 2868: 2866: 2863: 2861: 2858: 2856: 2853: 2851: 2848: 2846: 2843: 2841: 2838: 2836: 2833: 2831: 2828: 2827: 2826: 2823: 2822: 2820: 2818: 2814: 2808: 2805: 2802: 2797: 2792: 2788: 2782: 2779: 2775: 2772: 2771: 2770: 2769:Bronchiolitis 2767: 2765: 2762: 2760: 2758: 2755: 2754: 2751: 2748: 2746: 2743: 2739: 2736: 2734: 2731: 2729: 2725: 2722: 2719: 2716: 2714: 2711: 2710: 2709: 2706: 2704: 2702: 2699: 2698: 2695: 2692: 2690: 2688: 2685: 2684: 2682: 2680: 2675: 2671: 2668: 2665: 2660: 2655: 2651: 2641: 2638: 2636: 2633: 2631: 2629: 2628: 2624: 2623: 2620: 2617: 2615: 2613: 2612: 2608: 2607: 2604: 2601: 2599: 2596: 2594: 2591: 2588: 2585: 2583: 2581: 2580: 2576: 2575: 2572: 2569: 2566: 2563: 2561: 2558: 2556: 2553: 2551: 2548: 2546: 2543: 2541: 2539: 2538: 2534: 2533: 2530: 2527: 2524: 2521: 2517: 2514: 2513: 2512: 2509: 2507: 2505: 2504: 2500: 2499: 2497: 2495: 2491: 2485: 2482: 2480: 2477: 2475: 2472: 2470: 2468: 2467: 2463: 2462: 2457: 2454: 2452: 2449: 2447: 2444: 2443: 2442: 2441: 2437: 2435: 2432: 2430: 2427: 2423: 2420: 2418: 2415: 2413: 2410: 2409: 2408: 2405: 2403: 2401: 2400: 2396: 2395: 2392: 2389: 2387: 2385: 2384: 2380: 2379: 2377: 2375: 2371: 2368: 2365: 2360: 2355: 2351: 2347: 2340: 2335: 2333: 2328: 2326: 2321: 2320: 2317: 2309: 2303: 2299: 2294: 2293: 2287: 2282: 2279: 2275: 2272: 2270: 2267: 2265: 2262: 2260: 2257: 2255: 2251: 2248: 2247: 2237: 2233: 2232: 2228: 2227: 2224: 2220: 2213: 2209: 2208: 2204: 2202: 2198: 2197: 2193: 2189: 2187: 2183: 2182: 2178: 2174: 2173: 2170: 2165: 2161: 2154: 2146: 2142: 2138: 2134: 2130: 2126: 2122: 2118: 2111: 2108: 2105: 2104:2009 Addendum 2101: 2095: 2092: 2080: 2074: 2071: 2066: 2062: 2058: 2054: 2050: 2046: 2039: 2036: 2025:on 2017-10-04 2024: 2020: 2019:"Berylliosis" 2013: 2010: 2006: 2005:0-521-59221-6 2002: 1998: 1992: 1989: 1984: 1978: 1974: 1973: 1965: 1962: 1957: 1953: 1949: 1945: 1941: 1937: 1933: 1929: 1925: 1921: 1917: 1913: 1905: 1902: 1897: 1893: 1889: 1885: 1881: 1877: 1873: 1869: 1862: 1859: 1854: 1850: 1846: 1842: 1838: 1834: 1830: 1826: 1819: 1817: 1813: 1808: 1804: 1799: 1794: 1790: 1786: 1782: 1778: 1774: 1770: 1766: 1759: 1757: 1755: 1751: 1746: 1742: 1738: 1734: 1730: 1726: 1722: 1718: 1714: 1710: 1706: 1699: 1696: 1691: 1687: 1683: 1679: 1675: 1671: 1664: 1661: 1656: 1652: 1647: 1642: 1638: 1634: 1630: 1626: 1622: 1618: 1614: 1607: 1604: 1599: 1595: 1590: 1585: 1581: 1577: 1573: 1569: 1565: 1558: 1556: 1552: 1547: 1543: 1539: 1535: 1530: 1525: 1521: 1517: 1513: 1506: 1504: 1502: 1498: 1493: 1489: 1484: 1479: 1475: 1471: 1467: 1463: 1459: 1452: 1450: 1448: 1444: 1439: 1433: 1430: 1424: 1421: 1416: 1412: 1407: 1402: 1398: 1394: 1390: 1386: 1382: 1375: 1373: 1369: 1364: 1358: 1354: 1347: 1344: 1339: 1335: 1331: 1327: 1320: 1317: 1312: 1308: 1303: 1298: 1293: 1288: 1284: 1280: 1276: 1269: 1266: 1263: 1259: 1253: 1250: 1246: 1240: 1237: 1232: 1228: 1224: 1220: 1216: 1212: 1205: 1203: 1199: 1194: 1190: 1186: 1182: 1178: 1174: 1170: 1166: 1159: 1156: 1151: 1147: 1143: 1139: 1135: 1131: 1127: 1123: 1119: 1112: 1109: 1103: 1098: 1094: 1090: 1085: 1080: 1077:(22): AB042. 1076: 1072: 1068: 1061: 1058: 1053: 1049: 1045: 1041: 1034: 1031: 1026: 1022: 1018: 1014: 1010: 1006: 998: 996: 994: 992: 988: 983: 979: 975: 971: 964: 961: 949: 943: 940: 935: 929: 922: 918: 914: 909: 904: 900: 896: 892: 888: 884: 877: 874: 869: 865: 861: 857: 853: 849: 846:(7): 487–93. 845: 841: 834: 832: 828: 824: 818: 816: 812: 807: 803: 799: 795: 790: 785: 781: 777: 773: 766: 763: 758: 754: 750: 746: 742: 738: 734: 730: 723: 720: 715: 711: 707: 703: 699: 695: 691: 687: 679: 676: 671: 667: 662: 657: 653: 649: 645: 641: 637: 633: 629: 622: 619: 614: 608: 604: 597: 594: 589: 585: 581: 577: 573: 569: 565: 561: 557: 553: 546: 543: 538: 534: 530: 526: 523:(2): 464–73. 522: 518: 511: 508: 496: 489: 486: 482: 476: 474: 472: 470: 466: 460: 458: 455: 450: 446: 444: 439: 432: 430: 426: 423: 419: 412: 410: 404: 402: 401:is required. 400: 397:and whatever 396: 391: 388: 385: 379: 377: 373: 371: 362: 360: 358: 353: 349: 341: 339: 336: 332: 327: 323: 319: 317: 313: 309: 305: 298: 295: 293: 290: 288: 285: 281: 278: 275: 271: 269: 266: 265: 263: 261: 258: 257: 256: 249: 242: 240: 238: 234: 229: 227: 223: 218: 214: 210: 206: 201: 200:of the lung. 199: 195: 191: 187: 183: 175: 173: 170: 168: 163: 161: 157: 153: 149: 145: 141: 136: 134: 130: 125: 123: 119: 115: 110: 108: 99: 97: 94: 92: 88: 84: 80: 76: 72: 68: 64: 56: 53: 51: 47: 42: 38: 33: 29: 25: 20: 4577: 4487:Deficiencies 4474: 4466: 4458: 4450: 4442: 4434: 4293: 4264: 4091:Right to sit 4081:Potty parity 3674:Tennis elbow 3669:Surfer's ear 3614:Mesothelioma 3584:Hearing loss 3483: 3281:Pneumothorax 3234:Lung abscess 3216: 3086: 3075:Pneumocystis 3036:Pneumococcal 2849: 2817:lung disease 2813:occupational 2791:Interstitial 2756: 2700: 2686: 2659:lung disease 2625: 2619:Epiglottitis 2609: 2577: 2571:Laryngospasm 2535: 2516:Strep throat 2501: 2464: 2440:nasal septum 2438: 2397: 2381: 2291: 2229: 2205: 2190: 2175: 2120: 2116: 2110: 2094: 2083:. Retrieved 2073: 2048: 2044: 2038: 2027:. Retrieved 2023:the original 2012: 1996: 1991: 1971: 1964: 1915: 1911: 1904: 1874:(1): 54–60. 1871: 1867: 1861: 1828: 1824: 1772: 1768: 1712: 1708: 1698: 1673: 1669: 1663: 1620: 1616: 1606: 1571: 1567: 1519: 1515: 1465: 1461: 1432: 1423: 1388: 1384: 1352: 1346: 1329: 1325: 1319: 1285:(2): 65–76. 1282: 1278: 1268: 1261: 1257: 1252: 1239: 1214: 1210: 1168: 1164: 1158: 1125: 1121: 1111: 1074: 1070: 1060: 1046:(2): 104–9. 1043: 1039: 1033: 1008: 1004: 973: 969: 963: 952:. Retrieved 942: 928:cite journal 920: 890: 886: 876: 843: 839: 779: 775: 765: 732: 728: 722: 692:(1): 25–44. 689: 685: 678: 635: 631: 621: 602: 596: 558:(2): 161–4. 555: 551: 545: 520: 516: 510: 499:. Retrieved 488: 451: 447: 440: 436: 427: 424: 420: 416: 413:Epidemiology 408: 392: 389: 386: 383: 374: 366: 345: 328: 324: 320: 301: 268:Tuberculosis 254: 230: 226:autoimmunity 209:MHC class II 202: 194:phagocytized 179: 176:Pathogenesis 171: 164: 137: 126: 114:tuberculosis 111: 103: 95: 70: 66: 62: 61: 4578:Berylliosis 4127:Drug policy 4064:Legislation 3770:Professions 3594:Indium lung 3489:Brucellosis 3484:Berylliosis 3379:Common cold 3326:Fibrothorax 3309:Chylothorax 3304:Hydrothorax 3257:mediastinum 3217:circulatory 3212:Atelectasis 3019:By pathogen 3011:pneumonitis 2998:Restrictive 2978:Sarcoidosis 2850:Berylliosis 2796:restrictive 2757:unspecified 2679:obstructive 2662:(including 2579:vocal cords 2511:Pharyngitis 2474:Tonsillitis 2429:Nasal polyp 2364:common cold 2357:(including 2102:. See also 1332:: 197–211. 976:(1): 7–19. 970:Sarcoidosis 308:chest x-ray 304:lung biopsy 260:Sarcoidosis 186:macrophages 156:weight loss 152:joint aches 118:sarcoidosis 63:Berylliosis 55:Pulmonology 27:Other names 22:Berylliosis 4733:Categories 4525:Molybdenum 4227:Toxic tort 4177:Job strain 4147:Ergonomics 4122:Break room 3644:Radium jaw 3634:Phossy jaw 3509:Chalicosis 3479:Barotrauma 3469:Asbestosis 3299:Hemothorax 3101:Aspiration 3063:Chlamydiae 3053:Mycoplasma 3041:Klebsiella 2899:Bagassosis 2885:Byssinosis 2860:Chalicosis 2835:Asbestosis 2830:Aluminosis 2764:Bronchitis 2635:Tracheitis 2611:epiglottis 2560:Laryngitis 2434:Rhinorrhea 2085:2008-09-18 2029:2012-08-20 1122:Toxicology 1003:Disease". 954:2008-09-18 501:2009-08-21 497:. Medscape 461:References 363:Prevention 148:chest pain 107:granulomas 4739:Beryllium 4520:Manganese 4515:Potassium 4469:hosphorus 3948:Checklist 3916:ISO 45001 3904:Standards 3654:Silicosis 3464:Acrodynia 3374:Influenza 3319:Malignant 3082:Parasitic 3031:Bacterial 3006:Pneumonia 2875:Silicosis 2870:Siderosis 2840:Baritosis 2674:Bronchial 2422:Hay fever 2391:Sinusitis 2276:from the 2231:eMedicine 1940:0340-0131 1888:1073-449X 1845:0003-0805 1789:1470-7926 1729:1545-9624 1538:0962-7480 1185:0033-8419 1165:Radiology 1093:2305-5839 798:0903-1936 749:1567-5769 706:0046-8177 652:0022-1007 380:Treatment 243:Diagnosis 79:beryllium 50:Specialty 4550:Toxicity 4535:Selenium 4495:Chromium 4343:Elements 4277:Journals 4266:Category 4192:Overwork 4110:See also 3863:(Canada) 3854:National 3817:Agencies 3679:Tinnitus 3549:Erethism 3456:injuries 3451:diseases 3389:COVID-19 3182:BOOP-COP 3149:Broncho- 3092:Chemical 2880:Talcosis 2801:fibrosis 2654:Lower RT 2407:Rhinitis 2354:Upper RT 2145:11215967 2137:10428708 2065:23794247 1956:39949745 1948:11355290 1896:15374840 1745:19773286 1737:15631056 1690:72430473 1546:22705916 1492:19894178 1338:21000285 1311:20386622 1231:21084914 1150:12504341 1052:12870719 1025:25398119 917:24995984 868:27610317 860:21186201 757:11811929 670:23797096 588:41564437 580:16231190 405:Outcomes 352:Beryllia 205:HLA-DPB1 198:fibrosis 4686:Related 4461:itrogen 4445:ydrogen 4295:Commons 3875:(Spain) 3869:(Italy) 3696:hygiene 3494:Burnout 2701:chronic 2627:trachea 2503:pharynx 2383:sinuses 2236:med/222 2212:D001607 2117:Science 1920:Bibcode 1853:8214955 1807:9326165 1798:1128986 1655:8933038 1646:1469683 1637:3433014 1598:8933039 1589:1469698 1483:2774897 1415:9679108 1406:1569745 1302:2847329 1243:ATSDR. 1193:3575713 1130:Bibcode 1102:5159372 982:7617981 908:4269484 806:9877510 714:5521721 661:3698527 560:Bibcode 537:3277503 433:History 312:CT scan 217:HLA-DP2 75:disease 4530:Sodium 4510:Iodine 4500:Copper 4425:CHONPS 3978:Hazard 3941:Safety 3474:Asthma 3070:Fungal 2724:Asthma 2537:larynx 2466:tonsil 2304:  2143:  2135:  2063:  2003:  1979:  1954:  1946:  1938:  1894:  1886:  1851:  1843:  1805:  1795:  1787:  1743:  1735:  1727:  1688:  1653:  1643:  1635:  1596:  1586:  1544:  1536:  1490:  1480:  1413:  1403:  1359:  1336:  1309:  1299:  1229:  1191:  1183:  1148:  1099:  1091:  1050:  1023:  980:  915:  905:  866:  858:  804:  796:  755:  747:  712:  704:  668:  658:  650:  609:  586:  578:  535:  297:Asthma 158:, and 4477:ulfur 4453:xygen 4437:arbon 4117:Break 3205:Other 3154:Lobar 3105:Lipid 3026:Viral 2925:Other 2687:acute 2664:LRTIs 2589:(LPR) 2567:(LPR) 2545:Croup 2525:(LPR) 2359:URTIs 2252:U.S. 2186:J63.2 2141:S2CID 1952:S2CID 1741:S2CID 1686:S2CID 1633:JSTOR 864:S2CID 584:S2CID 479:OSHA 167:liver 160:fever 140:cough 65:, or 4540:Zinc 4505:Iron 3928:(US) 3892:(US) 3881:(UK) 3819:and 3454:and 3384:SARS 3187:NSIP 2932:ARDS 2733:AERD 2708:COPD 2494:Neck 2399:nose 2374:Head 2302:ISBN 2298:103– 2207:MeSH 2196:9-CM 2133:PMID 2061:PMID 2001:ISBN 1977:ISBN 1944:PMID 1936:ISSN 1892:PMID 1884:ISSN 1849:PMID 1841:ISSN 1803:PMID 1785:ISSN 1733:PMID 1725:ISSN 1651:PMID 1594:PMID 1542:PMID 1534:ISSN 1488:PMID 1411:PMID 1357:ISBN 1334:PMID 1307:PMID 1227:PMID 1189:PMID 1181:ISSN 1146:PMID 1089:ISSN 1048:PMID 1021:PMID 978:PMID 934:link 913:PMID 887:Cell 856:PMID 802:PMID 794:ISSN 753:PMID 745:ISSN 710:PMID 702:ISSN 666:PMID 648:ISSN 607:ISBN 576:PMID 533:PMID 333:and 228:." 224:and 184:and 142:and 116:and 3177:DIP 3172:UIP 3164:IIP 2201:503 2192:ICD 2177:ICD 2125:doi 2121:285 2053:doi 1928:doi 1876:doi 1872:171 1833:doi 1829:148 1793:PMC 1777:doi 1717:doi 1678:doi 1641:PMC 1625:doi 1621:104 1584:PMC 1576:doi 1572:104 1524:doi 1478:PMC 1470:doi 1401:PMC 1393:doi 1389:102 1297:PMC 1287:doi 1219:doi 1173:doi 1169:163 1138:doi 1126:183 1097:PMC 1079:doi 1013:doi 1009:190 903:PMC 895:doi 891:158 848:doi 784:doi 737:doi 694:doi 656:PMC 640:doi 636:210 568:doi 525:doi 521:137 454:DOE 310:or 135:). 71:CBD 4735:: 3192:RB 2300:. 2288:. 2234:: 2210:: 2199:: 2184:: 2181:10 2139:. 2131:. 2119:. 2059:. 2049:56 2047:. 1950:. 1942:. 1934:. 1926:. 1916:74 1914:. 1890:. 1882:. 1870:. 1847:. 1839:. 1827:. 1815:^ 1801:. 1791:. 1783:. 1773:54 1771:. 1767:. 1753:^ 1739:. 1731:. 1723:. 1711:. 1707:. 1684:. 1672:. 1649:. 1639:. 1631:. 1619:. 1615:. 1592:. 1582:. 1570:. 1566:. 1554:^ 1540:. 1532:. 1520:62 1518:. 1514:. 1500:^ 1486:. 1476:. 1464:. 1460:. 1446:^ 1409:. 1399:. 1387:. 1383:. 1371:^ 1330:28 1328:. 1305:. 1295:. 1283:13 1281:. 1277:. 1225:. 1215:34 1213:. 1201:^ 1187:. 1179:. 1167:. 1144:. 1136:. 1124:. 1120:. 1095:. 1087:. 1073:. 1069:. 1044:20 1042:. 1019:. 1007:. 990:^ 974:12 972:. 930:}} 926:{{ 919:. 911:. 889:. 885:. 862:. 854:. 844:68 842:. 830:^ 814:^ 800:. 792:. 780:12 778:. 774:. 751:. 743:. 731:. 708:. 700:. 688:. 664:. 654:. 646:. 634:. 630:. 582:. 574:. 566:. 556:79 554:. 531:. 519:. 468:^ 445:. 318:. 169:. 162:. 154:, 150:, 93:. 4475:S 4467:P 4459:N 4451:O 4443:H 4435:C 4330:e 4323:t 4316:v 4097:) 4093:( 4087:) 4083:( 3433:e 3426:t 3419:v 3283:/ 3254:/ 3103:/ 3094:/ 3008:/ 2949:/ 2803:) 2799:( 2793:/ 2726:( 2720:) 2676:/ 2666:) 2656:/ 2366:) 2361:, 2338:e 2331:t 2324:v 2310:. 2194:- 2179:- 2169:D 2147:. 2127:: 2088:. 2067:. 2055:: 2032:. 1985:. 1958:. 1930:: 1922:: 1898:. 1878:: 1855:. 1835:: 1809:. 1779:: 1747:. 1719:: 1713:1 1692:. 1680:: 1674:7 1657:. 1627:: 1600:. 1578:: 1548:. 1526:: 1494:. 1472:: 1466:6 1417:. 1395:: 1365:. 1340:. 1313:. 1289:: 1233:. 1221:: 1195:. 1175:: 1152:. 1140:: 1132:: 1105:. 1081:: 1075:4 1054:. 1027:. 1015:: 984:. 957:. 936:) 897:: 870:. 850:: 808:. 786:: 759:. 739:: 733:2 716:. 696:: 690:1 672:. 642:: 615:. 590:. 570:: 562:: 539:. 527:: 504:. 276:) 220:" 69:(

Index


Specialty
Pulmonology
disease
beryllium
beryllium poisoning
acute beryllium poisoning
occupational lung disease
granulomas
tuberculosis
sarcoidosis
granulomas without a necrotic core
restrictive lung disease
diffusion capacity
cough
shortness of breath
chest pain
joint aches
weight loss
fever
liver
CD4+ helper T-lymphocytes
macrophages
noncaseating granulomas
phagocytized
fibrosis
HLA-DPB1
MHC class II
antigen presenting cells
HLA-DP2

Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.

↑